Isoshamixanthone: a new pyrano xanthone from endophytic Aspergillus sp. ASCLA and absolute configuration of epiisoshamixanthone.
Kamel RA, Abdel-Razek AS, Hamed A, Ibrahim RR, Stammler H-G, Frese M, Sewald N, Shaaban M (2019)
Natural product research: 1-11.
Zeitschriftenaufsatz
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Autor*in
Kamel, Reem A;
Abdel-Razek, Ahmed S;
Hamed, Abdelaaty;
Ibrahim, Reham R;
Stammler, Hans-GeorgUniBi;
Frese, MarcelUniBi
;
Sewald, NorbertUniBi
;
Shaaban, Mohamed
![](https://pub.uni-bielefeld.de/images/icon_orcid.png)
![](https://pub.uni-bielefeld.de/images/icon_orcid.png)
Einrichtung
Abstract / Bemerkung
Isoshamixanthone (1), a new stereoisomeric pyrano xanthone together with the previously known fungal metabolites, epiisoshamixanthone (2), sterigmatocystin (3), arugosin C (4), norlichexanthone (5), diorcinol (6), ergosterol and methyllinoleate, were obtained from the endophytic fungal strain Aspergillus sp. ASCLA isolated from leaf tissues of the medicinal plant Callistemon subulatus. The chemical structure of the new xanthone (1) was elucidated by extensive 1D, 2D NMR, and ESI HR mass measurements, and by comparison with literature data. The constitutions and absolute configurations of 1 and epiisoshamixanthone (2) were additionally confirmed by X-ray crystallography. Compounds 1,2 were evaluated for their potential anticancer activity using the human cervix carcinoma cell line (KB-3-1). The antimicrobial activities of the fungal extract and compounds 1,2 were studied using a panel of pathogenic microorganisms as well.
Erscheinungsjahr
2019
Zeitschriftentitel
Natural product research
Seite(n)
1-11
eISBN
1478-6427
ISSN
1478-6419
Page URI
https://pub.uni-bielefeld.de/record/2933690
Zitieren
Kamel RA, Abdel-Razek AS, Hamed A, et al. Isoshamixanthone: a new pyrano xanthone from endophytic Aspergillus sp. ASCLA and absolute configuration of epiisoshamixanthone. Natural product research. 2019:1-11.
Kamel, R. A., Abdel-Razek, A. S., Hamed, A., Ibrahim, R. R., Stammler, H. - G., Frese, M., Sewald, N., et al. (2019). Isoshamixanthone: a new pyrano xanthone from endophytic Aspergillus sp. ASCLA and absolute configuration of epiisoshamixanthone. Natural product research, 1-11. doi:10.1080/14786419.2018.1548458
Kamel, Reem A, Abdel-Razek, Ahmed S, Hamed, Abdelaaty, Ibrahim, Reham R, Stammler, Hans-Georg, Frese, Marcel, Sewald, Norbert, and Shaaban, Mohamed. 2019. “Isoshamixanthone: a new pyrano xanthone from endophytic Aspergillus sp. ASCLA and absolute configuration of epiisoshamixanthone.”. Natural product research, 1-11.
Kamel, R. A., Abdel-Razek, A. S., Hamed, A., Ibrahim, R. R., Stammler, H. - G., Frese, M., Sewald, N., and Shaaban, M. (2019). Isoshamixanthone: a new pyrano xanthone from endophytic Aspergillus sp. ASCLA and absolute configuration of epiisoshamixanthone. Natural product research, 1-11.
Kamel, R.A., et al., 2019. Isoshamixanthone: a new pyrano xanthone from endophytic Aspergillus sp. ASCLA and absolute configuration of epiisoshamixanthone. Natural product research, , p 1-11.
R.A. Kamel, et al., “Isoshamixanthone: a new pyrano xanthone from endophytic Aspergillus sp. ASCLA and absolute configuration of epiisoshamixanthone.”, Natural product research, 2019, pp. 1-11.
Kamel, R.A., Abdel-Razek, A.S., Hamed, A., Ibrahim, R.R., Stammler, H.-G., Frese, M., Sewald, N., Shaaban, M.: Isoshamixanthone: a new pyrano xanthone from endophytic Aspergillus sp. ASCLA and absolute configuration of epiisoshamixanthone. Natural product research. 1-11 (2019).
Kamel, Reem A, Abdel-Razek, Ahmed S, Hamed, Abdelaaty, Ibrahim, Reham R, Stammler, Hans-Georg, Frese, Marcel, Sewald, Norbert, and Shaaban, Mohamed. “Isoshamixanthone: a new pyrano xanthone from endophytic Aspergillus sp. ASCLA and absolute configuration of epiisoshamixanthone.”. Natural product research (2019): 1-11.
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