article
Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics
published
yes
Sangeeta
Bhatia
author
Pedro
Feijão
author 38801322
Andrew R.
Francis
author
66100
department
Modellers of large-scale genome rearrangement events, in which segments of DNA are inverted, moved, swapped, or even inserted or deleted, have found a natural syntax in the language of permutations. Despite this, there has been a wide range of modelling choices, assumptions and interpretations that make navigating the literature a significant challenge. Indeed, even authors of papers that use permutations to model genome rearrangement can struggle to interpret each others' work, because of subtle differences in basic assumptions that are often deeply ingrained (and consequently sometimes not even mentioned). In this paper, we describe the different ways in which permutations have been used to model genomes and genome rearrangement events, presenting some features and limitations of each approach, and show how the various models are related. This paper will help researchers navigate the landscape of permutation-based genome rearrangement models and make it easier for authors to present clear and consistent models.
Springer2018
eng
Genome rearrangementPermutationSymmetric groupDouble cut and joinInversion
BULLETIN OF MATHEMATICAL BIOLOGY
0092-8240
1522-9602
30288640
00045008010001010.1007/s11538-018-0514-3
80123227-3246
Bhatia S, Feijão P, Francis AR (2018) <br />Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics.<br />BULLETIN OF MATHEMATICAL BIOLOGY 80(12): 3227-3246.
Bhatia S, Feijão P, Francis AR. Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics. <em>BULLETIN OF MATHEMATICAL BIOLOGY</em>. 2018;80(12):3227-3246.
<div style="text-indent:-25px; padding-left:25px;padding-bottom:0px;">Bhatia, S., Feijão, P., & Francis, A. R. (2018). Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics. <em>BULLETIN OF MATHEMATICAL BIOLOGY</em>, <em>80</em>(12), 3227-3246. doi:10.1007/s11538-018-0514-3</div>
S. Bhatia, P. Feijão, and A.R. Francis, “Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics”, <em>BULLETIN OF MATHEMATICAL BIOLOGY</em>, vol. 80, 2018, pp. 3227-3246.
<div style="text-indent:-25px; padding-left:25px;padding-bottom:0px;">Bhatia, Sangeeta, Feijão, Pedro, and Francis, Andrew R. 2018. “Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics”. <em>BULLETIN OF MATHEMATICAL BIOLOGY</em> 80 (12): 3227-3246.</div>
Bhatia S, Feijão P, Francis AR (2018) <br /><em>BULLETIN OF MATHEMATICAL BIOLOGY</em> 80(12): 3227-3246.
Bhatia, Sangeeta, Feijão, Pedro, and Francis, Andrew R. “Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics”. <em>BULLETIN OF MATHEMATICAL BIOLOGY</em> 80.12 (2018): 3227-3246.
<div style="text-indent:-25px; padding-left:25px;padding-bottom:0px;">Bhatia, S., Feijão, P. & Francis, A.R. (2018). Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics. <em>BULLETIN OF MATHEMATICAL BIOLOGY</em>, <em>80</em>(12), 3227-3246. Springer. doi:10.1007/s11538-018-0514-3.</div>
S. Bhatia, P. Feijão, and A. R. Francis, “Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics”, <em>BULLETIN OF MATHEMATICAL BIOLOGY</em>, <strong>2018</strong>, <em>80</em>, 3227-3246.
Bhatia, S., Feijão, P., & Francis, A. R. (2018). Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics. <em>BULLETIN OF MATHEMATICAL BIOLOGY</em>, <em>80</em>(12), 3227-3246. doi:10.1007/s11538-018-0514-3
Bhatia, S., Feijão, P., & Francis, A.R., 2018. Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics. <em>BULLETIN OF MATHEMATICAL BIOLOGY</em>, 80(12), p 3227-3246.
Bhatia, S.; Feijão, P.; Francis, A. R. (2018): Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics <em>BULLETIN OF MATHEMATICAL BIOLOGY</em>,80:(12): 3227-3246.
Bhatia, S., Feijão, P., and Francis, A. R. (2018). Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics. <em>BULLETIN OF MATHEMATICAL BIOLOGY</em> 80, 3227-3246.
Bhatia, S., Feijão, P., Francis, A.R.: Position and Content Paradigms in Genome Rearrangements. The Wild and Crazy World of Permutations in Genomics. BULLETIN OF MATHEMATICAL BIOLOGY. 80, 3227-3246 (2018).
29327542018-12-18T15:09:31Z2018-12-21T14:47:24Z