Psychological Factors Associated with Phantom Limb Pain. A Review of Recent Findings

Fuchs, Xaver; Flor, Herta; Bekrater-Bodmann, Robin

Psychological Factors Associated with Phantom Limb Pain. A Review of Recent Findings

Fuchs X, Flor H, Bekrater-Bodmann R (2018)
Pain Research and Management 2018(Special Issue): 5080123.

Zeitschriftenaufsatz | Veröffentlicht | Englisch

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5080123.fuchs.pdf 1.56 MB

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https://www.hindawi.com/journals/prm/2018/5080123/

DOI

https://doi.org/10.1155/2018/5080123

URN

urn:nbn:de:0070-pub-29207787

Autor*in

Fuchs, Xaver^UniBi ; Flor, Herta; Bekrater-Bodmann, Robin

Einrichtung

Fakultät für Psychologie und Sportwissenschaft > Abteilung für Psychologie > Arbeitseinheit 14 - Biopsychologie und Kognitive Neurowissenschaften

Abstract / Bemerkung

Phantom limb pain (PLP) is a common phenomenon occurring after the amputation of a limb and can be accompanied by serious suffering. Psychological factors have been shown to play an important role in other types of chronic pain, where they are pivotal in the acquisition and maintenance of pain symptoms. For PLP, however, the interaction between pain and psychological variables is less well documented. In this review, we summarize research on the role of emotional, motivational, cognitive, and perceptual factors in PLP. The reported findings indicate that emotional factors modulate PLP but might be less important compared to other types of chronic pain. Additional factors such as the amount of disability and adjustment to the amputation appear to also play a role. Bidirectional relationships between stress and PLP have been shown quite consistently, and the potential of stress and tension reduction in PLP treatment could be further exploited. Little is known about the role of cognitive variables such as attention or expectation. Catastrophizing seems to aggravate PLP and could be targeted in treatment. Body perception is altered in PLP and poses a potential target for novel mechanistic treatments. More research on psychological factors and their interactions in PLP is needed.

Erscheinungsjahr

2018

Zeitschriftentitel

Pain Research and Management

Band

2018

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Special Issue

Art.-Nr.

5080123

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Creative Commons Namensnennung 4.0 International Public License (CC-BY 4.0)

ISSN

1203-6765

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Open-Access-Publikationskosten wurden durch die Deutsche Forschungsgemeinschaft und die Universität Bielefeld gefördert.

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https://pub.uni-bielefeld.de/record/2920778

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Fuchs X, Flor H, Bekrater-Bodmann R. Psychological Factors Associated with Phantom Limb Pain. A Review of Recent Findings. Pain Research and Management. 2018;2018(Special Issue): 5080123.

Fuchs, X., Flor, H., & Bekrater-Bodmann, R. (2018). Psychological Factors Associated with Phantom Limb Pain. A Review of Recent Findings. Pain Research and Management, 2018(Special Issue), 5080123. doi:10.1155/2018/5080123

Fuchs, Xaver, Flor, Herta, and Bekrater-Bodmann, Robin. 2018. “Psychological Factors Associated with Phantom Limb Pain. A Review of Recent Findings”. Pain Research and Management 2018 (Special Issue): 5080123.

Fuchs, X., Flor, H., and Bekrater-Bodmann, R. (2018). Psychological Factors Associated with Phantom Limb Pain. A Review of Recent Findings. Pain Research and Management 2018:5080123.

Fuchs, X., Flor, H., & Bekrater-Bodmann, R., 2018. Psychological Factors Associated with Phantom Limb Pain. A Review of Recent Findings. Pain Research and Management, 2018(Special Issue): 5080123.

X. Fuchs, H. Flor, and R. Bekrater-Bodmann, “Psychological Factors Associated with Phantom Limb Pain. A Review of Recent Findings”, Pain Research and Management, vol. 2018, 2018, : 5080123.

Fuchs, X., Flor, H., Bekrater-Bodmann, R.: Psychological Factors Associated with Phantom Limb Pain. A Review of Recent Findings. Pain Research and Management. 2018, : 5080123 (2018).

Fuchs, Xaver, Flor, Herta, and Bekrater-Bodmann, Robin. “Psychological Factors Associated with Phantom Limb Pain. A Review of Recent Findings”. Pain Research and Management 2018.Special Issue (2018): 5080123.

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258 References

Daten bereitgestellt von Europe PubMed Central.

EMDR in the treatment of chronic phantom limb pain.
Schneider J, Hofmann A, Rost C, Shapiro F., Pain Med 9(1), 2008
PMID: 18254770

Catastrophizing-a prognostic factor for outcome in patients with low back pain: a systematic review.
Wertli MM, Eugster R, Held U, Steurer J, Kofmehl R, Weiser S., Spine J 14(11), 2014
PMID: 24607845

Does use of a myoelectric prosthesis prevent cortical reorganization and phantom limb pain?
Lotze M, Grodd W, Birbaumer N, Erb M, Huse E, Flor H., Nat. Neurosci. 2(6), 1999
PMID: 10448212

Memory impairment in chronic pain patients and the related neuropsychological mechanisms: a review.
Liu X, Li L, Tang F, Wu S, Hu Y., Acta Neuropsychiatr 26(4), 2014
PMID: 25279415

Phantom limb pain: a case of maladaptive CNS plasticity?
Flor H, Nikolajsen L, Staehelin Jensen T., Nat. Rev. Neurosci. 7(11), 2006
PMID: 17053811

A comprehensive literature review of chronic pain and memory.
Mazza S, Frot M, Rey AE., Prog. Neuropsychopharmacol. Biol. Psychiatry 87(Pt B), 2017
PMID: 28797640

Mirror therapy for phantom limb pain.
Chan BL, Witt R, Charrow AP, Magee A, Howard R, Pasquina PF, Heilman KM, Tsao JW., N. Engl. J. Med. 357(21), 2007
PMID: 18032777

Neurophysiology of hypnosis.
Vanhaudenhuyse A, Laureys S, Faymonville ME., Neurophysiol Clin 44(4), 2013
PMID: 25306075

Phantom limb pain: a review of the literature on attributes and potential mechanisms.
Hill A., J Pain Symptom Manage 17(2), 1999
PMID: 10069153

Phantom limb pain: an energy/trauma model.
Leskowitz E., Explore (NY) 10(6), 2014
PMID: 25264368

Neuronal plasticity: increasing the gain in pain.
Woolf CJ, Salter MW., Science 288(5472), 2000
PMID: 10846153

The use of pain coping strategies by patients with phantom limb pain.
Hill A., Pain 55(3), 1993
PMID: 8121696

Phantom-limb pain: characteristics, causes, and treatment.
Flor H., Lancet Neurol 1(3), 2002
PMID: 12849487

Cognitive-emotional sensitization contributes to wind-up-like pain in phantom limb pain patients.
Vase L, Nikolajsen L, Christensen B, Egsgaard LL, Arendt-Nielsen L, Svensson P, Staehelin Jensen T., Pain 152(1), 2010
PMID: 21067864

Pain site and impairment in individuals with amputation pain.
Marshall HM, Jensen MP, Ehde DM, Campbell KM., Arch Phys Med Rehabil 83(8), 2002
PMID: 12161833

Phantom limb pain--a phenomenon of proprioceptive memory?
Anderson-Barnes VC, McAuliffe C, Swanberg KM, Tsao JW., Med. Hypotheses 73(4), 2009
PMID: 19556069

Bodily illusions in health and disease: physiological and clinical perspectives and the concept of a cortical 'body matrix'.
Moseley GL, Gallace A, Spence C., Neurosci Biobehav Rev 36(1), 2011
PMID: 21477616

DSM-IV pain disorder in the general population. An exploration of the structure and threshold of medically unexplained pain symptoms.
Frohlich C, Jacobi F, Wittchen HU., Eur Arch Psychiatry Clin Neurosci 256(3), 2005
PMID: 16328107

Psychological distress in amputees with phantom limb pain.
Whyte AS, Niven CA., J Pain Symptom Manage 22(5), 2001
PMID: 11728797

Disability and depression in rheumatoid arthritis. A multi-trait, multi-method investigation.
Peck JR, Smith TW, Ward JR, Milano R., Arthritis Rheum. 32(9), 1989
PMID: 2528352

Left is where the L is right. Significantly delayed reaction time in limb laterality recognition in both CRPS and phantom limb pain patients.
Reinersmann A, Haarmeyer GS, Blankenburg M, Frettloh J, Krumova EK, Ocklenburg S, Maier C., Neurosci. Lett. 486(3), 2010
PMID: 20887773

Cognitive and emotional control of pain and its disruption in chronic pain.
Bushnell MC, Ceko M, Low LA., Nat. Rev. Neurosci. 14(7), 2013
PMID: 23719569

Internal consistencies of the original and revised Beck Depression Inventory.
Beck AT, Steer RA., J Clin Psychol 40(6), 1984
PMID: 6511949

Predicting transition to chronic pain.
Apkarian AV, Baliki MN, Farmer MA., Curr. Opin. Neurol. 26(4), 2013
PMID: 23823463

Anxiety and depression in patients with amputated limbs suffering from phantom pain: a comparative study with non-phantom chronic pain.
Kazemi H, Ghassemi S, Fereshtehnejad SM, Amini A, Kolivand PH, Doroudi T., Int J Prev Med 4(2), 2013
PMID: 23543814

[Prevalence and risk factors of phantom limb pain and phantom limb sensations in Germany. A nationwide field survey].
Kern U, Busch V, Rockland M, Kohl M, Birklein F., Schmerz 23(5), 2009
PMID: 19322592

Treatment of chronic phantom limb pain using a trauma-focused psychological approach.
de Roos C, Veenstra AC, de Jongh A, den Hollander-Gijsman M, van der Wee NJ, Zitman FG, van Rood YR., Pain Res Manag 15(2), 2010
PMID: 20458374

Post-amputation pain is associated with the recall of an impaired body representation in dreams-results from a nation-wide survey on limb amputees.
Bekrater-Bodmann R, Schredl M, Diers M, Reinhard I, Foell J, Trojan J, Fuchs X, Flor H., PLoS ONE 10(3), 2015
PMID: 25742626

The role of coping in adjustment to phantom limb pain.
Hill A, Niven CA, Knussen C., Pain 62(1), 1995
PMID: 7478711

Positive affect protects against deficient safety learning during extinction of fear of movement-related pain in healthy individuals scoring relatively high on trait anxiety.
Meulders A, Meulders M, Vlaeyen JW., J Pain 15(6), 2014
PMID: 24650796

Physiological properties of unmyelinated fiber projection to the spinal cord.
Mendell LM., Exp. Neurol. 16(3), 1966
PMID: 5928985

Evidence for working memory deficits in chronic pain: a systematic review and meta-analysis.
Berryman C, Stanton TR, Jane Bowering K, Tabor A, McFarlane A, Lorimer Moseley G., Pain 154(8), 2013
PMID: 23707355

Limb Laterality Recognition Score: A Reliable Clinical Measure Related to Phantom Limb Pain.
Wong CK, Wong CK., Pain Med 19(4), 2018
PMID: 29024959

Phantom motor execution facilitated by machine learning and augmented reality as treatment for phantom limb pain: a single group, clinical trial in patients with chronic intractable phantom limb pain.
Ortiz-Catalan M, Guðmundsdottir RA, Kristoffersen MB, Zepeda-Echavarria A, Caine-Winterberger K, Kulbacka-Ortiz K, Widehammar C, Eriksson K, Stockselius A, Ragno C, Pihlar Z, Burger H, Hermansson L., Lancet 388(10062), 2016
PMID: 27916234

Amputation, phantom pain and subjective well-being: a qualitative study.
Bosmans JC, Suurmeijer TP, Hulsink M, van der Schans CP, Geertzen JH, Dijkstra PU., Int J Rehabil Res 30(1), 2007
PMID: 17293714

Chronic pain associated with upper-limb loss.
Hanley MA, Ehde DM, Jensen M, Czerniecki J, Smith DG, Robinson LR., Am J Phys Med Rehabil 88(9), 2009
PMID: 19692791

Depressive symptoms and mental health service utilization among persons with limb loss: results of a national survey.
Darnall BD, Ephraim P, Wegener ST, Dillingham T, Pezzin L, Rossbach P, MacKenzie EJ., Arch Phys Med Rehabil 86(4), 2005
PMID: 15827913

Psychophysical measures of sensitization to tonic heat discriminate chronic pain patients.
Kleinbohl D, Holzl R, Moltner A, Rommel C, Weber C, Osswald PM., Pain 81(1-2), 1999
PMID: 10353491

Sex differences in pain and psychological functioning in persons with limb loss.
Hirsh AT, Dillworth TM, Ehde DM, Jensen MP., J Pain 11(1), 2009
PMID: 19734105

The role of psychological factors in chronic pain.
Turk DC., Acta Anaesthesiol Scand 43(9), 1999
PMID: 10522734

A psychiatric study of amputees.
Shukla GD, Sahu SC, Tripathi RP, Gupta DK., Br J Psychiatry 141(), 1982
PMID: 7116072

Chronic pain and distorted body image: Implications for multisensory feedback interventions.
Senkowski D, Heinz A., Neurosci Biobehav Rev 69(), 2016
PMID: 27524638

Evidence for a change in neural processing in phantom limb pain patients.
Larbig W, Montoya P, Flor H, Bilow H, Weller S, Birbaumer N., Pain 67(2-3), 1996
PMID: 8951921

Hypnotherapy: a forgotten modality in managing chronic post-traumatic upper limb pain.
Mack P, Yam AK, Chin AY., Ann. Acad. Med. Singap. 42(7), 2013
PMID: 23949268

Psychophysical correlates of phantom limb experience.
Katz J., J. Neurol. Neurosurg. Psychiatry 55(9), 1992
PMID: 1402973

A prospective study of factors associated with the presence of phantom limb pain six months after major lower limb amputation in patients with peripheral vascular disease.
Richardson C, Glenn S, Horgan M, Nurmikko T., J Pain 8(10), 2007
PMID: 17631056

Chronic pain-associated depression: antecedent or consequence of chronic pain? A review.
Fishbain DA, Cutler R, Rosomoff HL, Rosomoff RS., Clin J Pain 13(2), 1997
PMID: 9186019

A diathesis-stress model of chronic pain and disability following traumatic injury.
Turk DC., Pain Res Manag 7(1), 2002
PMID: 16231063

Coping with amputation and phantom limb pain.
Pucher I, Kickinger W, Frischenschlager O., J Psychosom Res 46(4), 1999
PMID: 10340237

The relationship of perceptual phenomena and cortical reorganization in upper extremity amputees.
Grusser SM, Winter C, Muhlnickel W, Denke C, Karl A, Villringer K, Flor H., Neuroscience 102(2), 2001
PMID: 11166112

Phantom limbs: pain, embodiment, and scientific advances in integrative therapies.
Lenggenhager B, Arnold CA, Giummarra MJ., Wiley Interdiscip Rev Cogn Sci 5(2), 2014
PMID: 26304309

Pain catastrophizing and cortical responses in amputees with varying levels of phantom limb pain: a high-density EEG brain-mapping study.
Vase L, Egsgaard LL, Nikolajsen L, Svensson P, Jensen TS, Arendt-Nielsen L., Exp Brain Res 218(3), 2012
PMID: 22349560

Beyond the body image: a qualitative study on how adults experience lower limb amputation.
Senra H, Oliveira RA, Leal I, Vieira C., Clin Rehabil 26(2), 2011
PMID: 21908476

The hospital anxiety and depression scale.
Zigmond AS, Snaith RP., Acta Psychiatr Scand 67(6), 1983
PMID: 6880820

Do artificial limbs become part of the user? New evidence.
McDonnell PM, Scott RN, Dickison J, Theriault RA, Wood B., J Rehabil Res Dev 26(2), 1989
PMID: 2724149

Psychosocial adjustment to lower-limb amputation: a review.
Horgan O, MacLachlan M., Disabil Rehabil 26(14-15), 2004
PMID: 15497913

Temporal relationships between changes in phantom limb pain intensity and changes in surface electromyogram of the residual limb.
Sherman RA, Griffin VD, Evans CB, Grana AS., Int J Psychophysiol 13(1), 1992
PMID: 1522035

The relationship between situational stress and phantom limb pain: cross-lagged correlational data from six month pain logs.
Arena JG, Sherman RA, Bruno GM, Smith JD., J Psychosom Res 34(1), 1990
PMID: 2313614

Pavlovian conditioning of muscular responses in chronic pain patients: central and peripheral correlates.
Schneider C, Palomba D, Flor H., Pain 112(3), 2004
PMID: 15561378

Local anesthetic sympathectomy restores fMRI cortical maps in CRPS I after upper extremity stellate blockade: a prospective case study.
Stude P, Enax-Krumova EK, Lenz M, Lissek S, Nicolas V, Peters S, Westermann A, Tegenthoff M, Maier C., Pain Physician 17(5), 2014
PMID: 25247914

Cognitions, coping and social environment predict adjustment to phantom limb pain.
Jensen MP, Ehde DM, Hoffman AJ, Patterson DR, Czerniecki JM, Robinson LR., Pain 95(1-2), 2002
PMID: 11790476

Assessment of stress-related psychophysiological reactions in chronic back pain patients.
Flor H, Turk DC, Birbaumer N., J Consult Clin Psychol 53(3), 1985
PMID: 3159767

Phantom limb pain and bodily awareness: current concepts and future directions.
Giummarra MJ, Moseley GL., Curr Opin Anaesthesiol 24(5), 2011
PMID: 21772144

Psychophysiological stress responses in amputees with and without phantom limb pain.
Angrilli A, Koster U., Physiol. Behav. 68(5), 2000
PMID: 10764900

The influence of preamputation pain on postamputation stump and phantom pain.
Nikolajsen L, Ilkjaer S, Kroner K, Christensen JH, Jensen TS., Pain 72(3), 1997
PMID: 9313280

Impact of psychological factors in the experience of pain.
Linton SJ, Shaw WS., Phys Ther 91(5), 2011
PMID: 21451097

Treatment of phantom limb pain with combined EMG and thermal biofeedback: a case report.
Belleggia G, Birbaumer N., Appl Psychophysiol Biofeedback 26(2), 2001
PMID: 11480164

Mirrored, imagined and executed movements differentially activate sensorimotor cortex in amputees with and without phantom limb pain.
Diers M, Christmann C, Koeppe C, Ruf M, Flor H., Pain 149(2), 2010
PMID: 20359825

Musculoskeletal pain and overuse syndromes in adult acquired major upper-limb amputees.
Ostlie K, Franklin RJ, Skjeldal OH, Skrondal A, Magnus P., Arch Phys Med Rehabil 92(12), 2011
PMID: 22133243

Phantom limb, phantom pain and stump pain in amputees during the first 6 months following limb amputation.
Jensen TS, Krebs B, Nielsen J, Rasmussen P., Pain 17(3), 1983
PMID: 6657285

Maladaptive plasticity: imprinting of past experiences onto phantom limb schemata.
Giummarra MJ, Georgiou-Karistianis N, Nicholls ME, Gibson SJ, Chou M, Bradshaw JL., Clin J Pain 27(8), 2011
PMID: 21487290

Phantom pain, residual limb pain, and back pain in amputees: results of a national survey.
Ephraim PL, Wegener ST, MacKenzie EJ, Dillingham TR, Pezzin LE., Arch Phys Med Rehabil 86(10), 2005
PMID: 16213230

Amputation and prosthesis implantation shape body and peripersonal space representations.
Canzoneri E, Marzolla M, Amoresano A, Verni G, Serino A., Sci Rep 3(), 2013
PMID: 24088746

Graded motor imagery for pathologic pain: a randomized controlled trial.
Moseley GL., Neurology 67(12), 2006
PMID: 17082465

Psychological factors influencing chronic phantom limb pain: an analysis of the literature.
Sherman RA, Sherman CJ, Bruno GM., Pain 28(3), 1987
PMID: 3554115

The use of coping strategies in chronic low back pain patients: relationship to patient characteristics and current adjustment.
Rosenstiel AK, Keefe FJ., Pain 17(1), 1983
PMID: 6226916

Mirror therapy for phantom limb pain: brain changes and the role of body representation.
Foell J, Bekrater-Bodmann R, Diers M, Flor H., Eur J Pain 18(5), 2013
PMID: 24327313

Concurrent variation of burning phantom limb and stump pain with near surface blood flow in the stump.
Sherman RA, Bruno GM., Orthopedics 10(10), 1987
PMID: 3684789

Psycho-social transitions: comparison between reactions to loss of a limb and loss of a spouse.
Parkes CM., Br J Psychiatry 127(), 1975
PMID: 1182377

Learning and memory in pain pathways.
Sandkuhler J., Pain 88(2), 2000
PMID: 11050365

Psychiatric sequelae of amputation : ii long term effects.
Trivedi JK, Mall CP, Mishra US, Sharma VP, Dalal PK, Katiyar M, Srivastava S, Sinha PK., Indian J Psychiatry 39(4), 1997
PMID: 21584100

Depression and anxiety symptoms after lower limb amputation: the rise and fall.
Singh R, Ripley D, Pentland B, Todd I, Hunter J, Hutton L, Philip A., Clin Rehabil 23(3), 2009
PMID: 19218302

Reorganization of motor and somatosensory cortex in upper extremity amputees with phantom limb pain.
Karl A, Birbaumer N, Lutzenberger W, Cohen LG, Flor H., J. Neurosci. 21(10), 2001
PMID: 11331390

Assessment of pain-related cognitions in chronic pain patients.
Flor H, Behle DJ, Birbaumer N., Behav Res Ther 31(1), 1993
PMID: 8417730

Left and right hand recognition in upper limb amputees.
Nico D, Daprati E, Rigal F, Parsons L, Sirigu A., Brain 127(Pt 1), 2003
PMID: 14607796

Prevalence and characteristics of phantom limb pain and residual limb pain in the long term after upper limb amputation.
Desmond DM, Maclachlan M., Int J Rehabil Res 33(3), 2010
PMID: 20101187

Longitudinal relationships between anxiety, depression, and pain: results from a two-year cohort study of lower extremity trauma patients.
Castillo RC, Wegener ST, Heins SE, Haythornthwaite JA, Mackenzie EJ, Bosse MJ; LEAP Study Group, MacKenzie EJ, Bosse MJ, Burgess AR, Castillo RC, Jones AL, Kellam JF, McAndrew MP, McCarthy ML, Patterson B, Sanders R, Smith DG, Starr A, Swiontkowski MF, Travison TG, Webb LX., Pain 154(12), 2013
PMID: 23994104

Maladaptive plasticity, memory for pain and phantom limb pain: review and suggestions for new therapies.
Flor H., Expert Rev Neurother 8(5), 2008
PMID: 18457537

Phantom pain and health-related quality of life in lower limb amputees.
van der Schans CP, Geertzen JH, Schoppen T, Dijkstra PU., J Pain Symptom Manage 24(4), 2002
PMID: 12505212

Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation.
Flor H, Elbert T, Knecht S, Wienbruch C, Pantev C, Birbaumer N, Larbig W, Taub E., Nature 375(6531), 1995
PMID: 7777055

Neural correlates of mental transformations of the body-in-space.
Bonda E, Petrides M, Frey S, Evans A., Proc. Natl. Acad. Sci. U.S.A. 92(24), 1995
PMID: 7479961

Central neuroplasticity and pathological pain.
Melzack R, Coderre TJ, Katz J, Vaccarino AL., Ann. N. Y. Acad. Sci. 933(), 2001
PMID: 12000018

Factors determining the persistence of phantom pain in the amputee.
Parkes CM., J Psychosom Res 17(2), 1973
PMID: 4741689

Psychosocial predictors of long-term adjustment to lower-limb amputation and phantom limb pain.
Hanley MA, Jensen MP, Ehde DM, Hoffman AJ, Patterson DR, Robinson LR., Disabil Rehabil 26(14-15), 2004
PMID: 15497917

Published treatments of phantom limb pain.
Sherman RA., Am J Phys Med 59(5), 1980
PMID: 7425113

When less is more - Implicit preference for incomplete bodies in xenomelia.
Macauda G, Bekrater-Bodmann R, Brugger P, Lenggenhager B., J Psychiatr Res 84(), 2016
PMID: 27776292

Variation in phantom limb pain: results of a diary study.
Whyte AS, Niven CA., J Pain Symptom Manage 22(5), 2001
PMID: 11728798

Patterns of cortical reorganization in complex regional pain syndrome.
Maihofner C, Handwerker HO, Neundorfer B, Birklein F., Neurology 61(12), 2003
PMID: 14694034

Relationship between chronic pain and brain reorganization after deafferentation: A systematic review of functional MRI findings.
Jutzeler CR, Curt A, Kramer JL., Neuroimage Clin 9(), 2015
PMID: 26740913

Hypnotic approaches for chronic pain management: clinical implications of recent research findings.
Jensen MP, Patterson DR., Am Psychol 69(2), 2014
PMID: 24547802

Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art.
Vlaeyen JW, Linton SJ., Pain 85(3), 2000
PMID: 10781906

Synaesthesia in phantom limbs induced with mirrors.
Ramachandran VS, Rogers-Ramachandran D., Proc. Biol. Sci. 263(1369), 1996
PMID: 8637922

Biofeedback in the treatment of phantom limb pain: a time-series analysis.
Harden RN, Houle TT, Green S, Remble TA, Weinland SR, Colio S, Lauzon J, Kuiken T., Appl Psychophysiol Biofeedback 30(1), 2005
PMID: 15889588

The relationship between catastrophizing and disability in amputees experiencing phantom pain.
Whyte A, Carroll LJ., Disabil Rehabil 26(11), 2004
PMID: 15204503

The contribution of sympathetic mechanisms to postamputation phantom and residual limb pain: a pilot study.
Cohen SP, Gambel JM, Raja SN, Galvagno S., J Pain 12(8), 2011
PMID: 21481650

The mystery of phantom pain: growing evidence for psychophysiological mechanisms.
Sherman RA, Arena JG, Sherman CJ, Ernst JL., Biofeedback Self Regul 14(4), 1989
PMID: 2698750

Affective distress and amputation-related pain among older men with long-term, traumatic limb amputations.
Desmond DM, MacLachlan M., J Pain Symptom Manage 31(4), 2006
PMID: 16632084

Placebo analgesia: psychological and neurobiological mechanisms.
Colloca L, Klinger R, Flor H, Bingel U., Pain 154(4), 2013
PMID: 23473783

Can experimentally induced positive affect attenuate generalization of fear of movement-related pain?
Geschwind N, Meulders M, Peters ML, Vlaeyen JW, Meulders A., J Pain 16(3), 2014
PMID: 25536535

Impact of Event Scale: a cross-validation study and some empirical evidence supporting a conceptual model of stress response syndromes.
Zilberg NJ, Weiss DS, Horowitz MJ., J Consult Clin Psychol 50(3), 1982
PMID: 7096742

Immediate and long-term phantom limb pain in amputees: incidence, clinical characteristics and relationship to pre-amputation limb pain.
Jensen TS, Krebs B, Nielsen J, Rasmussen P., Pain 21(3), 1985
PMID: 3991231

Cognitive-processing bias in chronic pain: a review and integration.
Pincus T, Morley S., Psychol Bull 127(5), 2001
PMID: 11548969

Psychiatric sequelae of amputation : I immediate effects.
Mall CP, Trivedi JK, Mishra US, Sharma VP, Dalal PK, Katiyar M, Srivastava S, Sinha PK., Indian J Psychiatry 39(4), 1997
PMID: 21584099

Targeting cortical representations in the treatment of chronic pain: a review.
Moseley GL, Flor H., Neurorehabil Neural Repair 26(6), 2012
PMID: 22331213

Decrease in phantom limb pain associated with prosthesis-induced increased use of an amputation stump in humans.
Weiss T, Miltner WH, Adler T, Bruckner L, Taub E., Neurosci. Lett. 272(2), 1999
PMID: 10507559

Pain 'memories' in phantom limbs: review and clinical observations.
Katz J, Melzack R., Pain 43(3), 1990
PMID: 2293143

Comparison of brain activity between motor imagery and mental rotation of the hand tasks: a functional magnetic resonance imaging study.
Hamada H, Matsuzawa D, Sutoh C, Hirano Y, Chakraborty S, Ito H, Tsuji H, Obata T, Shimizu E., Brain Imaging Behav 12(6), 2018
PMID: 29368208

Preoperative state anxiety, acute postoperative pain, and analgesic use in persons undergoing lower limb amputation.
Raichle KA, Osborne TL, Jensen MP, Ehde DM, Smith DG, Robinson LR., Clin J Pain 31(8), 2015
PMID: 26153780

Plasticity in the Visual System is Associated with Prosthesis Use in Phantom Limb Pain.
Preißler S, Dietrich C, Blume KR, Hofmann GO, Miltner WH, Weiss T., Front Hum Neurosci 7(), 2013
PMID: 23805096

The biopsychosocial approach to chronic pain: scientific advances and future directions.
Gatchel RJ, Peng YB, Peters ML, Fuchs PN, Turk DC., Psychol Bull 133(4), 2007
PMID: 17592957

Phantom limb pain, cortical reorganization and the therapeutic effect of mental imagery.
MacIver K, Lloyd DM, Kelly S, Roberts N, Nurmikko T., Brain 131(Pt 8), 2008
PMID: 18567624

Cortical reorganisation and chronic pain: implications for rehabilitation.
Flor H., J Rehabil Med (41 Suppl), 2003
PMID: 12817660

Treatment of phantom limb pain with muscular relaxation training to disrupt the pain--anxiety--tension cycle.
Sherman RA, Gall N, Gormly J., Pain 6(1), 1979
PMID: 370738

Placebo, nocebo, and neuropathic pain.
Vase L, Skyt I, Hall KT., Pain 157 Suppl 1(), 2016
PMID: 26785162

Phantom limb pain after lower limb trauma: origins and treatments.
Foell J, Bekrater-Bodmann R, Flor H, Cole J., Int J Low Extrem Wounds 10(4), 2011
PMID: 22184752

[The applicability of the West Haven-Yale multidimensional pain inventory in German-speaking countries. Data on the reliability and validity of the MPI-D.].
Flor H, Rudy TE, Birbaumer N, Streit B, Schugens MM., Schmerz 4(2), 1990
PMID: 18415223

Psychiatric aspects of pain and the phantom limb.
Frazier SH, Kolb LC., Orthop. Clin. North Am. 1(2), 1970
PMID: 5521868

Phantom limb perception interferes with motor imagery after unilateral upper-limb amputation.
Lyu Y, Guo X, Bekrater-Bodmann R, Flor H, Tong S., Sci Rep 6(), 2016
PMID: 26879749

The menacing phantom: what pulls the trigger?
Giummarra MJ, Georgiou-Karistianis N, Nicholls ME, Gibson SJ, Chou M, Bradshaw JL., Eur J Pain 15(7), 2011
PMID: 21316273