Membrane electroporation: chemical thermodynamics and flux kinetics revisited and refined

Neumann E, Kakorin S (2018)
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 47(4): 373-387.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Abstract / Bemerkung
The chemical thermodynamic concept for membrane electroporation is critically revisited. The hysteresis in the electric field dependence of the rapid in-field electroporation events (on the in-field hysteresis branch) and the slower post-field pore resealing process (zero-field hysteresis branch) is a typical ensemble property involving rapid single-pore opening-closing events that are temporally and spatially distributed. In the case of spherical membrane shells in homogeneous external fields, the acting local field is dependent on the polar-angular position. Hence, the experimental state distribution constant and the ensemble rate coefficients are statistical position averages; they are cosine square averages of the polar angle. Advanced flux analysis uses the concept of time-dependent flux coefficients reflecting the kinetics of the rate-limiting structural processes of electroporation and membrane resealing. The explicit integral flux equations rationalize the sigmoid onset of the in-field kinetics and quantify the post-field-stretched exponentials as exponentials of exponentials. Finally, the new analytical proposal for the evaluation of the electric field strength dependence of global cell electroporation data starts with the low-field range and continues with iterative parameter optimisation over the entire field strength range.
Stichworte
Electroporation hysteresis; Electrothermodynamical analysis; Pore state; ensemble; Time-dependent flux coefficient; Single-pore state statistics
Erscheinungsjahr
2018
Zeitschriftentitel
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Band
47
Ausgabe
4
Seite(n)
373-387
ISSN
0175-7571
eISSN
1432-1017
Page URI
https://pub.uni-bielefeld.de/record/2920687

Zitieren

Neumann E, Kakorin S. Membrane electroporation: chemical thermodynamics and flux kinetics revisited and refined. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2018;47(4):373-387.
Neumann, E., & Kakorin, S. (2018). Membrane electroporation: chemical thermodynamics and flux kinetics revisited and refined. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 47(4), 373-387. doi:10.1007/s00249-018-1305-3
Neumann, Eberhard, and Kakorin, Sergej. 2018. “Membrane electroporation: chemical thermodynamics and flux kinetics revisited and refined”. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 47 (4): 373-387.
Neumann, E., and Kakorin, S. (2018). Membrane electroporation: chemical thermodynamics and flux kinetics revisited and refined. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 47, 373-387.
Neumann, E., & Kakorin, S., 2018. Membrane electroporation: chemical thermodynamics and flux kinetics revisited and refined. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 47(4), p 373-387.
E. Neumann and S. Kakorin, “Membrane electroporation: chemical thermodynamics and flux kinetics revisited and refined”, EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, vol. 47, 2018, pp. 373-387.
Neumann, E., Kakorin, S.: Membrane electroporation: chemical thermodynamics and flux kinetics revisited and refined. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 47, 373-387 (2018).
Neumann, Eberhard, and Kakorin, Sergej. “Membrane electroporation: chemical thermodynamics and flux kinetics revisited and refined”. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 47.4 (2018): 373-387.

34 References

Daten bereitgestellt von Europe PubMed Central.


IG, Bioelechem Bioenerg 6(), 1979
Efficiency of high- and low-voltage pulse combinations for gene electrotransfer in muscle, liver, tumor, and skin.
Andre FM, Gehl J, Sersa G, Preat V, Hojman P, Eriksen J, Golzio M, Cemazar M, Pavselj N, Rols MP, Miklavcic D, Neumann E, Teissie J, Mir LM., Hum. Gene Ther. 19(11), 2008
PMID: 19866490

P, 2006
Kinetic analysis of receptor-controlled tracer efflux from sealed membrane fragments.
Bernhardt J, Neumann E., Proc. Natl. Acad. Sci. U.S.A. 75(8), 1978
PMID: 16592553
Kinetics, statistics, and energetics of lipid membrane electroporation studied by molecular dynamics simulations.
Bockmann RA, de Groot BL, Kakorin S, Neumann E, Grubmuller H., Biophys. J. 95(4), 2008
PMID: 18469089

CJF, 1973
Molecular dynamics simulations of lipid membrane electroporation.
Delemotte L, Tarek M., J. Membr. Biol. 245(9), 2012
PMID: 22644388

R, 2010

M, 1963
Electromediated formation of DNA complexes with cell membranes and its consequences for gene delivery.
Escoffre JM, Portet T, Favard C, Teissie J, Dean DS, Rols MP., Biochim. Biophys. Acta 1808(6), 2010
PMID: 21035428

C, Curr Opin Colloid Interface 15(), 2010

T, Phys Chem Chem Phys 4(), 2002

S, Eur Biophys J 27(), 1998

S, J Phys Chem B 107(), 2003
Numerical simulation of molecular uptake via electroporation.
Li J, Lin H., Bioelectrochemistry 82(1), 2011
PMID: 21621484

D, 2010
High-efficiency gene transfer into skeletal muscle mediated by electric pulses.
Mir LM, Bureau MF, Gehl J, Rangara R, Rouy D, Caillaud JM, Delaere P, Branellec D, Schwartz B, Scherman D., Proc. Natl. Acad. Sci. U.S.A. 96(8), 1999
PMID: 10200250

E, 1989

E, 2010
Permeability changes induced by electric impulses in vesicular membranes.
Neumann E, Rosenheck K., J. Membr. Biol. 10(3), 1972
PMID: 4667921
Gene transfer into mouse lyoma cells by electroporation in high electric fields.
Neumann E, Schaefer-Ridder M, Wang Y, Hofschneider PH., EMBO J. 1(7), 1982
PMID: 6329708
Mechanism of electroporative dye uptake by mouse B cells.
Neumann E, Toensing K, Kakorin S, Budde P, Frey J., Biophys. J. 74(1), 1998
PMID: 9449314
Fundamentals of electroporative delivery of drugs and genes.
Neumann E, Kakorin S, Toensing K., Bioelectrochem Bioenerg 48(1), 1999
PMID: 10228565
Local and transient structural changes in stratum corneum at high electric fields: contribution of Joule heating.
Pliquett U, Gallo S, Hui SW, Gusbeth Ch, Neumann E., Bioelectrochemistry 67(1), 2005
PMID: 15967399

M, Phys Chem Chem Phys 6(), 2004

KH, 2010

R, Acad Bras Cienc 30(), 1958

IP, 1989

T, 2010

JC, Bioelectrochem Bioenerg 41(), 1996

JC, 1989
Electric field mediated gene transfer.
Wong TK, Neumann E., Biochem. Biophys. Res. Commun. 107(2), 1982
PMID: 7126230
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