German Value Set for the EQ-5D-5L

Ludwig K, von der Schulenburg J-MG, Greiner W (2018)
PHARMACOECONOMICS 36(6): 663-674.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Ludwig, KristinaUniBi; von der Schulenburg, J. -Matthias Graf; Greiner, WolfgangUniBi
Abstract / Bemerkung
The objective of this study was to develop a value set for EQ-5D-5L based on the societal preferences of the German population. As the first country to do so, the study design used the improved EQ-5D-5L valuation protocol 2.0 developed by the EuroQol Group, including a feedback module as internal validation and a quality control process that was missing in the first wave of EQ-5D-5L valuation studies. A representative sample of the general German population (n = 1158) was interviewed using a composite time trade-off and a discrete choice experiment under close quality control. Econometric modeling was used to estimate values for all 3125 possible health states described by EQ-5D-5L. The value set was based on a hybrid model including all available information from the composite time trade-off and discrete choice experiment valuations without any exclusions due to data issues. The final German value set was constructed from a combination of a conditional logit model for the discrete choice experiment data and a censored at -1 Tobit model for the composite time trade-off data, correcting for heteroskedasticity. The value set had logically consistent parameter estimates (p < 0.001 for all coefficients). The predicted EQ-5D-5L index values ranged from -0.661 to 1. This study provided values for the health states of the German version of EQ-5D-5L representing the preferences of the German population. The study successfully employed for the first time worldwide the improved protocol 2.0. The value set enables the use of the EQ-5D-5L instrument in economic evaluations and in clinical studies.
Erscheinungsjahr
2018
Zeitschriftentitel
PHARMACOECONOMICS
Band
36
Ausgabe
6
Seite(n)
663-674
ISSN
1170-7690
eISSN
1179-2027
Page URI
https://pub.uni-bielefeld.de/record/2920300

Zitieren

Ludwig K, von der Schulenburg J-MG, Greiner W. German Value Set for the EQ-5D-5L. PHARMACOECONOMICS. 2018;36(6):663-674.
Ludwig, K., von der Schulenburg, J. - M. G., & Greiner, W. (2018). German Value Set for the EQ-5D-5L. PHARMACOECONOMICS, 36(6), 663-674. doi:10.1007/s40273-018-0615-8
Ludwig, K., von der Schulenburg, J. - M. G., and Greiner, W. (2018). German Value Set for the EQ-5D-5L. PHARMACOECONOMICS 36, 663-674.
Ludwig, K., von der Schulenburg, J.-M.G., & Greiner, W., 2018. German Value Set for the EQ-5D-5L. PHARMACOECONOMICS, 36(6), p 663-674.
K. Ludwig, J.-M.G. von der Schulenburg, and W. Greiner, “German Value Set for the EQ-5D-5L”, PHARMACOECONOMICS, vol. 36, 2018, pp. 663-674.
Ludwig, K., von der Schulenburg, J.-M.G., Greiner, W.: German Value Set for the EQ-5D-5L. PHARMACOECONOMICS. 36, 663-674 (2018).
Ludwig, Kristina, von der Schulenburg, J. -Matthias Graf, and Greiner, Wolfgang. “German Value Set for the EQ-5D-5L”. PHARMACOECONOMICS 36.6 (2018): 663-674.

6 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

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