Negation of protein-protein interactions: analysis and extraction
Sanchez Graillet O, Poesio M (2007)
Bioinformatics 23(13): i424--i432.
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Autor*in
Sanchez Graillet, OliviaUniBi 
;
Poesio, Massimo
;
Poesio, MassimoEinrichtung
Abstract / Bemerkung
**Motivation**: Negative information about protein–protein interactions—from uncertainty about the occurrence of an interaction to knowledge that it did not occur—is often of great use to biologists and could lead to important discoveries. Yet, to our knowledge, no proposals focusing on extracting such information have been proposed in the text mining literature.
**Results**: In this work, we present an analysis of the types of negative information that is reported, and a heuristic-based system using a full dependency parser to extract such information. We performed a preliminary evaluation study that shows encouraging results of our system. Finally, we have obtained an initial corpus of negative protein–protein interactions as basis for the construction of larger ones.
**Availability**:The corpus is available by request from the authors.
**Results**: In this work, we present an analysis of the types of negative information that is reported, and a heuristic-based system using a full dependency parser to extract such information. We performed a preliminary evaluation study that shows encouraging results of our system. Finally, we have obtained an initial corpus of negative protein–protein interactions as basis for the construction of larger ones.
**Availability**:The corpus is available by request from the authors.
Erscheinungsjahr
2007
Zeitschriftentitel
Bioinformatics
Band
23
Ausgabe
13
Seite(n)
i424--i432
eISSN
1367-4811
Page URI
https://pub.uni-bielefeld.de/record/2920008
Zitieren
Sanchez Graillet O, Poesio M. Negation of protein-protein interactions: analysis and extraction. Bioinformatics. 2007;23(13):i424--i432.
Sanchez Graillet, O., & Poesio, M. (2007). Negation of protein-protein interactions: analysis and extraction. Bioinformatics, 23(13), i424--i432. doi:10.1093/bioinformatics/btm184
Sanchez Graillet, Olivia, and Poesio, Massimo. 2007. “Negation of protein-protein interactions: analysis and extraction”. Bioinformatics 23 (13): i424--i432.
Sanchez Graillet, O., and Poesio, M. (2007). Negation of protein-protein interactions: analysis and extraction. Bioinformatics 23, i424--i432.
Sanchez Graillet, O., & Poesio, M., 2007. Negation of protein-protein interactions: analysis and extraction. Bioinformatics, 23(13), p i424--i432.
O. Sanchez Graillet and M. Poesio, “Negation of protein-protein interactions: analysis and extraction”, Bioinformatics, vol. 23, 2007, pp. i424--i432.
Sanchez Graillet, O., Poesio, M.: Negation of protein-protein interactions: analysis and extraction. Bioinformatics. 23, i424--i432 (2007).
Sanchez Graillet, Olivia, and Poesio, Massimo. “Negation of protein-protein interactions: analysis and extraction”. Bioinformatics 23.13 (2007): i424--i432.
Daten bereitgestellt von European Bioinformatics Institute (EBI)
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