Biotechnological production of amino acids and derivatives: current status and prospects

Leuchtenberger W, Huthmacher K, Drauz K (2005)
Applied Microbiology and Biotechnology 69(1): 1-8.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Leuchtenberger, WolfgangUniBi; Huthmacher, Klaus; Drauz, Karlheinz
Applied Microbiology and Biotechnology
0175-7598, 1432-0614
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Leuchtenberger W, Huthmacher K, Drauz K. Biotechnological production of amino acids and derivatives: current status and prospects. Applied Microbiology and Biotechnology. 2005;69(1):1-8.
Leuchtenberger, W., Huthmacher, K., & Drauz, K. (2005). Biotechnological production of amino acids and derivatives: current status and prospects. Applied Microbiology and Biotechnology, 69(1), 1-8. doi:10.1007/s00253-005-0155-y
Leuchtenberger, W., Huthmacher, K., and Drauz, K. (2005). Biotechnological production of amino acids and derivatives: current status and prospects. Applied Microbiology and Biotechnology 69, 1-8.
Leuchtenberger, W., Huthmacher, K., & Drauz, K., 2005. Biotechnological production of amino acids and derivatives: current status and prospects. Applied Microbiology and Biotechnology, 69(1), p 1-8.
W. Leuchtenberger, K. Huthmacher, and K. Drauz, “Biotechnological production of amino acids and derivatives: current status and prospects”, Applied Microbiology and Biotechnology, vol. 69, 2005, pp. 1-8.
Leuchtenberger, W., Huthmacher, K., Drauz, K.: Biotechnological production of amino acids and derivatives: current status and prospects. Applied Microbiology and Biotechnology. 69, 1-8 (2005).
Leuchtenberger, Wolfgang, Huthmacher, Klaus, and Drauz, Karlheinz. “Biotechnological production of amino acids and derivatives: current status and prospects”. Applied Microbiology and Biotechnology 69.1 (2005): 1-8.

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Thermostable Branched-Chain Amino Acid Transaminases From the Archaea Geoglobus acetivorans and Archaeoglobus fulgidus: Biochemical and Structural Characterization.
Isupov MN, Boyko KM, Sutter JM, James P, Sayer C, Schmidt M, Schönheit P, Nikolaeva AY, Stekhanova TN, Mardanov AV, Ravin NV, Bezsudnova EY, Popov VO, Littlechild JA., Front Bioeng Biotechnol 7(), 2019
PMID: 30733943
Whole Cell Actinobacteria as Biocatalysts.
Anteneh YS, Franco CMM., Front Microbiol 10(), 2019
PMID: 30833932
Fermentative production of the unnatural amino acid L-2-aminobutyric acid based on metabolic engineering.
Xu JM, Li JQ, Zhang B, Liu ZQ, Zheng YG., Microb Cell Fact 18(1), 2019
PMID: 30819198
Precise tuning of the glyoxylate cycle in Escherichia coli for efficient tyrosine production from acetate.
Jo M, Noh MH, Lim HG, Kang CW, Im DK, Oh MK, Jung GY., Microb Cell Fact 18(1), 2019
PMID: 30890173
Extracellular Proteolytic Activity and Amino Acid Production by Lactic Acid Bacteria Isolated from Malaysian Foods.
Toe CJ, Foo HL, Loh TC, Mohamad R, Abdul Rahim R, Idrus Z., Int J Mol Sci 20(7), 2019
PMID: 30974873
Metabolic engineering of Escherichia coli BL21 (DE3) for de novo production of L-DOPA from D-glucose.
Fordjour E, Adipah FK, Zhou S, Du G, Zhou J., Microb Cell Fact 18(1), 2019
PMID: 31023316
Efficient Biofilm-Based Fermentation Strategies for L-Threonine Production by Escherichia coli.
Chen T, Liu N, Ren P, Xi X, Yang L, Sun W, Yu B, Ying H, Ouyang P, Liu D, Chen Y., Front Microbiol 10(), 2019
PMID: 31428070
A systematic optimization of styrene biosynthesis in Escherichia coli BL21(DE3).
Liu C, Men X, Chen H, Li M, Ding Z, Chen G, Wang F, Liu H, Wang Q, Zhu Y, Zhang H, Xian M., Biotechnol Biofuels 11(), 2018
PMID: 29416559
Enzymatic asymmetric synthesis of chiral amino acids.
Xue YP, Cao CH, Zheng YG., Chem Soc Rev 47(4), 2018
PMID: 29362736
Rational design and analysis of an Escherichia coli strain for high-efficiency tryptophan production.
Chen Y, Liu Y, Ding D, Cong L, Zhang D., J Ind Microbiol Biotechnol 45(5), 2018
PMID: 29460214
Increasing L-threonine production in Escherichia coli by engineering the glyoxylate shunt and the L-threonine biosynthesis pathway.
Zhao H, Fang Y, Wang X, Zhao L, Wang J, Li Y., Appl Microbiol Biotechnol 102(13), 2018
PMID: 29713792
An Aminocaprolactam Racemase from Ochrobactrum anthropi with Promiscuous Amino Acid Ester Racemase Activity.
Frese A, Barrass SV, Sutton PW, Adams JP, Grogan G., Chembiochem (), 2018
PMID: 29897155
Making point mutations in Escherichia coli BL21 genome using the CRISPR-Cas9 system.
Wang X, He J, Le K., FEMS Microbiol Lett 365(14), 2018
PMID: 29596631
Complete genome sequence of Enterococcus durans KLDS6.0933, a potential probiotic strain with high cholesterol removal ability.
Li B, Evivie SE, Jin D, Meng Y, Li N, Yan F, Huo G, Liu F., Gut Pathog 10(), 2018
PMID: 30034545
Spatial organization of enzymes to enhance synthetic pathways in microbial chassis: a systematic review.
Qiu XY, Xie SS, Min L, Wu XM, Zhu LY, Zhu L., Microb Cell Fact 17(1), 2018
PMID: 30064437
Artificial Thermostable D-Amino Acid Dehydrogenase: Creation and Application.
Akita H, Hayashi J, Sakuraba H, Ohshima T., Front Microbiol 9(), 2018
PMID: 30123202
The colors of biotechnology: general overview and developments of white, green and blue areas.
Barcelos MCS, Lupki FB, Campolina GA, Nelson DL, Molina G., FEMS Microbiol Lett 365(21), 2018
PMID: 30256942
Increased production of L-serine in Escherichia coli through Adaptive Laboratory Evolution.
Mundhada H, Seoane JM, Schneider K, Koza A, Christensen HB, Klein T, Phaneuf PV, Herrgard M, Feist AM, Nielsen AT., Metab Eng 39(), 2017
PMID: 27908688
Production of (S)-2-aminobutyric acid and (S)-2-aminobutanol in Saccharomyces cerevisiae.
Weber N, Hatsch A, Labagnere L, Heider H., Microb Cell Fact 16(1), 2017
PMID: 28335772
Microbial metabolites in nutrition, healthcare and agriculture.
Singh R, Kumar M, Mittal A, Mehta PK., 3 Biotech 7(1), 2017
PMID: 28391479
Controlled defunctionalisation of biobased organic acids.
Verduyckt J, De Vos DE., Chem Commun (Camb) 53(42), 2017
PMID: 28367544
Current status on metabolic engineering for the production of l-aspartate family amino acids and derivatives.
Li Y, Wei H, Wang T, Xu Q, Zhang C, Fan X, Ma Q, Chen N, Xie X., Bioresour Technol 245(pt b), 2017
PMID: 28579173
Construction of a synthetic metabolic pathway for biosynthesis of the non-natural methionine precursor 2,4-dihydroxybutyric acid.
Walther T, Topham CM, Irague R, Auriol C, Baylac A, Cordier H, Dressaire C, Lozano-Huguet L, Tarrat N, Martineau N, Stodel M, Malbert Y, Maestracci M, Huet R, André I, Remaud-Siméon M, François JM., Nat Commun 8(), 2017
PMID: 28631755
A cost-effective approach to produce 15N-labelled amino acids employing Chlamydomonas reinhardtii CC503.
Nicolás Carcelén J, Marchante-Gayón JM, González PR, Valledor L, Cañal MJ, Alonso JIG., Microb Cell Fact 16(1), 2017
PMID: 28821247
Identification of a new gene yecC involved in threonine export in Escherichia coli.
Xu Y, Liu Y, Li F, Cao G, Zheng P, Sun J, Wen J, Zhang D., FEMS Microbiol Lett 364(17), 2017
PMID: 28911185
Investigation of the dynamics of aqueous proline solutions using neutron scattering and molecular dynamics simulations.
Malo de Molina P, Alvarez F, Frick B, Wildes A, Arbe A, Colmenero J., Phys Chem Chem Phys 19(40), 2017
PMID: 28984889
Microbial production of lactic acid: the latest development.
Juturu V, Wu JC., Crit Rev Biotechnol 36(6), 2016
PMID: 26287368
Production of protocatechuic acid by Corynebacterium glutamicum expressing chorismate-pyruvate lyase from Escherichia coli.
Okai N, Miyoshi T, Takeshima Y, Kuwahara H, Ogino C, Kondo A., Appl Microbiol Biotechnol 100(1), 2016
PMID: 26392137
Engineering of high yield production of L-serine in Escherichia coli.
Mundhada H, Schneider K, Christensen HB, Nielsen AT., Biotechnol Bioeng 113(4), 2016
PMID: 26416585
Taxonomy, Physiology, and Natural Products of Actinobacteria.
Barka EA, Vatsa P, Sanchez L, Gaveau-Vaillant N, Jacquard C, Meier-Kolthoff JP, Klenk HP, Clément C, Ouhdouch Y, van Wezel GP., Microbiol Mol Biol Rev 80(1), 2016
PMID: 26609051
Corynebacterium glutamicum Metabolic Engineering with CRISPR Interference (CRISPRi).
Cleto S, Jensen JV, Wendisch VF, Lu TK., ACS Synth Biol 5(5), 2016
PMID: 26829286
Efficient production of α-ketoglutarate in the gdh deleted Corynebacterium glutamicum by novel double-phase pH and biotin control strategy.
Li Y, Sun L, Feng J, Wu R, Xu Q, Zhang C, Chen N, Xie X., Bioprocess Biosyst Eng 39(6), 2016
PMID: 26946492
3-Methyl-1-butanol Biosynthesis in an Engineered Corynebacterium glutamicum.
Xiao S, Xu J, Chen X, Li X, Zhang Y, Yuan Z., Mol Biotechnol 58(5), 2016
PMID: 26961908
Screening of an Escherichia coli promoter library for a phenylalanine biosensor.
Mahr R, von Boeselager RF, Wiechert J, Frunzke J., Appl Microbiol Biotechnol 100(15), 2016
PMID: 27170323
Enzymatic dynamic kinetic resolution of racemic N-formyl- and N-carbamoyl-amino acids using immobilized L-N-carbamoylase and N-succinyl-amino acid racemase.
Soriano-Maldonado P, Las Heras-Vazquez FJ, Clemente-Jimenez JM, Rodriguez-Vico F, Martínez-Rodríguez S., Appl Microbiol Biotechnol 99(1), 2015
PMID: 24993356
L-Serine overproduction with minimization of by-product synthesis by engineered Corynebacterium glutamicum.
Zhu Q, Zhang X, Luo Y, Guo W, Xu G, Shi J, Xu Z., Appl Microbiol Biotechnol 99(4), 2015
PMID: 25434811
Genetic and metabolic engineering of microorganisms for the development of new flavor compounds from terpenic substrates.
Bution ML, Molina G, Abrahão MR, Pastore GM., Crit Rev Biotechnol 35(3), 2015
PMID: 24494701
Multigene editing in the Escherichia coli genome via the CRISPR-Cas9 system.
Jiang Y, Chen B, Duan C, Sun B, Yang J, Yang S., Appl Environ Microbiol 81(7), 2015
PMID: 25636838
Response of Fe-S cluster assembly machinery of Escherichia coli to mechanical stress in a model of amino-acid crystal fermentation.
Okutani S, Iwai T, Iwatani S, Matsuno K, Takahashi Y, Hase T., J Biosci Bioeng 120(3), 2015
PMID: 25682519
Regulation of the pstSCAB operon in Corynebacterium glutamicum by the regulator of acetate metabolism RamB.
Sorger-Herrmann U, Taniguchi H, Wendisch VF., BMC Microbiol 15(), 2015
PMID: 26021728
Synthesis of chemicals by metabolic engineering of microbes.
Sun X, Shen X, Jain R, Lin Y, Wang J, Sun J, Wang J, Yan Y, Yuan Q., Chem Soc Rev 44(11), 2015
PMID: 25940754
Two-step production of gamma-aminobutyric acid from cassava powder using Corynebacterium glutamicum and Lactobacillus plantarum.
Yang T, Rao Z, Kimani BG, Xu M, Zhang X, Yang ST., J Ind Microbiol Biotechnol 42(8), 2015
PMID: 26115763
Advances and needs for endotoxin-free production strains.
Taguchi S, Ooi T, Mizuno K, Matsusaki H., Appl Microbiol Biotechnol 99(22), 2015
PMID: 26362682
Metabolic Engineering of Pseudomonas putida KT2440 to Produce Anthranilate from Glucose.
Kuepper J, Dickler J, Biggel M, Behnken S, Jäger G, Wierckx N, Blank LM., Front Microbiol 6(), 2015
PMID: 26635771
Whole cell biotransformation for reductive amination reactions.
Klatte S, Lorenz E, Wendisch VF., Bioengineered 5(1), 2014
PMID: 24406456
Molecular characterization of a novel N-acetyltransferase from Chryseobacterium sp.
Takenaka S, Yoshida K, Tanaka K, Yoshida K., Appl Environ Microbiol 80(5), 2014
PMID: 24375143
Identification and methionine analog tolerance of environmental bacterial isolates selected on methionine analog containing medium.
Saengkerdsub S, Muthaiyan A, Lingbeck JM, O'Bryan CA, Crandall PG, Ricke SC., J Environ Sci Health B 49(4), 2014
PMID: 24502216
Processes to separate enantiomers.
Lorenz H, Seidel-Morgenstern A., Angew Chem Int Ed Engl 53(5), 2014
PMID: 24442686
Analysis of cepA encoding an efflux pump-like protein in Corynebacterium glutamicum.
Sim SY, Hong EJ, Kim Y, Lee HS., J Microbiol 52(4), 2014
PMID: 24535744
The substrate specificity, enantioselectivity and structure of the (R)-selective amine : pyruvate transaminase from Nectria haematococca.
Sayer C, Martinez-Torres RJ, Richter N, Isupov MN, Hailes HC, Littlechild JA, Ward JM., FEBS J 281(9), 2014
PMID: 24618038
Application of metabolic engineering for the biotechnological production of L-valine.
Oldiges M, Eikmanns BJ, Blombach B., Appl Microbiol Biotechnol 98(13), 2014
PMID: 24816722
Effect of cofactor folate on the growth of Corynebacterium glutamicum SYPS-062 and L-serine accumulation.
Zhang X, Xu G, Li H, Dou W, Xu Z., Appl Biochem Biotechnol 173(7), 2014
PMID: 24859773
Design and synthesis of (S)- and (R)-α-(phenyl)ethylamine-derived NH-type ligands and their application for the chemical resolution of α-amino acids.
Takeda R, Kawamura A, Kawashima A, Moriwaki H, Sato T, Aceña JL, Soloshonok VA., Org Biomol Chem 12(32), 2014
PMID: 25008025
Effect of steaming, blanching, and high temperature/high pressure processing on the amino Acid contents of commonly consumed korean vegetables and pulses.
Kim SY, Kim BM, Kim JB, Shanmugavelan P, Kim HW, Kim SY, Kim SN, Cho YS, Choi HS, Park KM., Prev Nutr Food Sci 19(3), 2014
PMID: 25320720
Enzymatic synthesis of chiral γ-amino acids using ω-transaminase.
Shon M, Shanmugavel R, Shin G, Mathew S, Lee SH, Yun H., Chem Commun (Camb) 50(84), 2014
PMID: 25207334
The crystal structures of apo and cAMP-bound GlxR from Corynebacterium glutamicum reveal structural and dynamic changes upon cAMP binding in CRP/FNR family transcription factors.
Townsend PD, Jungwirth B, Pojer F, Bußmann M, Money VA, Cole ST, Pühler A, Tauch A, Bott M, Cann MJ, Pohl E., PLoS One 9(12), 2014
PMID: 25469635
Toward biotechnological production of adipic acid and precursors from biorenewables.
Polen T, Spelberg M, Bott M., J Biotechnol 167(2), 2013
PMID: 22824738
Production of L-lysine on different silage juices using genetically engineered Corynebacterium glutamicum.
Neuner A, Wagner I, Sieker T, Ulber R, Schneider K, Peifer S, Heinzle E., J Biotechnol 163(2), 2013
PMID: 22898177
Genome-scale engineering for systems and synthetic biology.
Esvelt KM, Wang HH., Mol Syst Biol 9(), 2013
PMID: 23340847
Non-invasive online detection of microbial lysine formation in stirred tank bioreactors by using calorespirometry.
Regestein L, Maskow T, Tack A, Knabben I, Wunderlich M, Lerchner J, Büchs J., Biotechnol Bioeng 110(5), 2013
PMID: 23280310
A magnetic nanoparticles-zinc oxide/zinc hexacyanoferrate hybrid film for amperometric determination of tyrosine.
Narang J, Chauhan N, Pundir S, Pundir CS., Bioprocess Biosyst Eng 36(11), 2013
PMID: 23411873
Kinetic and thermodynamic characterization of lysine production process in Brevibacterium lactofermentum.
Ahmed S, Afzal M, Rajoka MI., Appl Biochem Biotechnol 170(1), 2013
PMID: 23475286
Actinobacterial melanins: current status and perspective for the future.
Manivasagan P, Venkatesan J, Sivakumar K, Kim SK., World J Microbiol Biotechnol 29(10), 2013
PMID: 23595596
Paraffin as oxygen vector modulates tyrosine phenol lyase production by Citrobacter freundii MTCC 2424.
Azmi W, Kumar A, Dev V., Acta Microbiol Immunol Hung 60(2), 2013
PMID: 23827746
Platform engineering of Corynebacterium glutamicum with reduced pyruvate dehydrogenase complex activity for improved production of L-lysine, L-valine, and 2-ketoisovalerate.
Buchholz J, Schwentner A, Brunnenkan B, Gabris C, Grimm S, Gerstmeir R, Takors R, Eikmanns BJ, Blombach B., Appl Environ Microbiol 79(18), 2013
PMID: 23835179
Characterization and molecular mechanism of AroP as an aromatic amino acid and histidine transporter in Corynebacterium glutamicum.
Shang X, Zhang Y, Zhang G, Chai X, Deng A, Liang Y, Wen T., J Bacteriol 195(23), 2013
PMID: 24056108
Actinobacterial melanins: current status and perspective for the future
Manivasagan P, Venkatesan J, Sivakumar K, Kim SK., World J Microbiol Biotechnol 29(10), 2013
PMID: IND500695696
Impact of different CO2/HCO3- levels on metabolism and regulation in Corynebacterium glutamicum.
Blombach B, Buchholz J, Busche T, Kalinowski J, Takors R., J Biotechnol 168(4), 2013
PMID: 24140290
Improvement of L-valine production at high temperature in Brevibacterium flavum by overexpressing ilvEBNrC genes.
Hou X, Ge X, Wu D, Qian H, Zhang W., J Ind Microbiol Biotechnol 39(1), 2012
PMID: 21706252
Modular engineering of L-tyrosine production in Escherichia coli.
Juminaga D, Baidoo EE, Redding-Johanson AM, Batth TS, Burd H, Mukhopadhyay A, Petzold CJ, Keasling JD., Appl Environ Microbiol 78(1), 2012
PMID: 22020510
Corynebacterium glutamicum as a potent biocatalyst for the bioconversion of pentose sugars to value-added products.
Gopinath V, Murali A, Dhar KS, Nampoothiri KM., Appl Microbiol Biotechnol 93(1), 2012
PMID: 22094976
Engineered Corynebacterium glutamicum as an endotoxin-free platform strain for lactate-based polyester production.
Song Y, Matsumoto K, Yamada M, Gohda A, Brigham CJ, Sinskey AJ, Taguchi S., Appl Microbiol Biotechnol 93(5), 2012
PMID: 22127753
Improvement of the redox balance increases L-valine production by Corynebacterium glutamicum under oxygen deprivation conditions.
Hasegawa S, Uematsu K, Natsuma Y, Suda M, Hiraga K, Jojima T, Inui M, Yukawa H., Appl Environ Microbiol 78(3), 2012
PMID: 22138982
Engineering Corynebacterium glutamicum for the production of pyruvate.
Wieschalka S, Blombach B, Eikmanns BJ., Appl Microbiol Biotechnol 94(2), 2012
PMID: 22228312
Deracemization of unnatural amino acid: homoalanine using D-amino acid oxidase and ω-transaminase.
Seo YM, Mathew S, Bea HS, Khang YH, Lee SH, Kim BG, Yun H., Org Biomol Chem 10(12), 2012
PMID: 22344532
Bio-processing of agro-byproducts to animal feed.
Ajila CM, Brar SK, Verma M, Tyagi RD, Godbout S, Valéro JR., Crit Rev Biotechnol 32(4), 2012
PMID: 22380921
Immobilized L-aspartate ammonia-lyase from Bacillus sp. YM55-1 as biocatalyst for highly concentrated L-aspartate synthesis.
Cárdenas-Fernández M, López C, Alvaro G, López-Santín J., Bioprocess Biosyst Eng 35(8), 2012
PMID: 22527030
The role of Corynebacterium glutamicum spiA gene in whcA-mediated oxidative stress gene regulation.
Park JS, Lee JY, Kim HJ, Kim ES, Kim P, Kim Y, Lee HS., FEMS Microbiol Lett 331(1), 2012
PMID: 22443283
Development and application of an arabinose-inducible expression system by facilitating inducer uptake in Corynebacterium glutamicum.
Zhang Y, Shang X, Lai S, Zhang G, Liang Y, Wen T., Appl Environ Microbiol 78(16), 2012
PMID: 22685153
Design of a recombinant Escherichia coli for producing L-phenylalanine from glycerol.
Thongchuang M, Pongsawasdi P, Chisti Y, Packdibamrung K., World J Microbiol Biotechnol 28(10), 2012
PMID: 22806734
Design constraints on a synthetic metabolism.
Bilgin T, Wagner A., PLoS One 7(6), 2012
PMID: 22768162
Postgenomic approaches to using corynebacteria as biocatalysts.
Vertès AA, Inui M, Yukawa H., Annu Rev Microbiol 66(), 2012
PMID: 22803796
Site-directed mutagenesis and over expression of aroG gene of Escherichia coli K-12.
Lin S, Meng X, Jiang J, Pang D, Jones G, OuYang H, Ren L., Int J Biol Macromol 51(5), 2012
PMID: 22819948
Metabolic shifts: a fitness perspective for microbial cell factories.
Goel A, Wortel MT, Molenaar D, Teusink B., Biotechnol Lett 34(12), 2012
PMID: 22936303
Design of a recombinant Escherichia coli for producing L-phenylalanine from glycerol
Thongchuang M, Pongsawasdi P, Chisti Y, Packdibamrung K., World J Microbiol Biotechnol 28(10), 2012
PMID: IND44745622
Metabolic engineering of Corynebacterium glutamicum aimed at alternative carbon sources and new products.
Zahoor A, Lindner SN, Wendisch VF., Comput Struct Biotechnol J 3(), 2012
PMID: 24688664
Interaction of transcriptional repressor ArgR with transcriptional regulator FarR at the argB promoter region in Corynebacterium glutamicum.
Lee SY, Park JM, Lee JH, Chang ST, Park JS, Kim YH, Min J., Appl Environ Microbiol 77(3), 2011
PMID: 21115700
Engineering cyanobacteria to generate high-value products.
Ducat DC, Way JC, Silver PA., Trends Biotechnol 29(2), 2011
PMID: 21211860
From zero to hero--design-based systems metabolic engineering of Corynebacterium glutamicum for L-lysine production.
Becker J, Zelder O, Häfner S, Schröder H, Wittmann C., Metab Eng 13(2), 2011
PMID: 21241816
Glutamate production from β-glucan using endoglucanase-secreting Corynebacterium glutamicum.
Tsuchidate T, Tateno T, Okai N, Tanaka T, Ogino C, Kondo A., Appl Microbiol Biotechnol 90(3), 2011
PMID: 21305281
Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae.
Yoshikawa K, Tanaka T, Ida Y, Furusawa C, Hirasawa T, Shimizu H., Yeast 28(5), 2011
PMID: 21341307
Corynebacterium glutamicum tailored for efficient isobutanol production.
Blombach B, Riester T, Wieschalka S, Ziert C, Youn JW, Wendisch VF, Eikmanns BJ., Appl Environ Microbiol 77(10), 2011
PMID: 21441331
Development of L-tryptophan production strains by defined genetic modification in Escherichia coli.
Zhao ZJ, Zou C, Zhu YX, Dai J, Chen S, Wu D, Wu J, Chen J., J Ind Microbiol Biotechnol 38(12), 2011
PMID: 21541714
Proteomics of corynebacteria: From biotechnology workhorses to pathogens.
Poetsch A, Haussmann U, Burkovski A., Proteomics 11(15), 2011
PMID: 21674800
Isolation, identification, and culture optimization of a novel glycinonitrile-hydrolyzing fungus-Fusarium oxysporum H3.
Gong JS, Lu ZM, Shi JS, Dou WF, Xu HY, Zhou ZM, Xu ZH., Appl Biochem Biotechnol 165(3-4), 2011
PMID: 21720838
D-lactic acid production by a genetically engineered strain Corynebacterium glutamicum
Jia X, Liu P, Li S, Li S, Wen J., World J Microbiol Biotechnol 27(9), 2011
PMID: IND44746264
Proline reduces the binding of transcriptional regulator ArgR to upstream of argB in Corynebacterium glutamicum.
Lee SY, Shin HS, Park JS, Kim YH, Min J., Appl Microbiol Biotechnol 86(1), 2010
PMID: 19798496
Model-driven evaluation of the production potential for growth-coupled products of Escherichia coli.
Feist AM, Zielinski DC, Orth JD, Schellenberger J, Herrgard MJ, Palsson BØ., Metab Eng 12(3), 2010
PMID: 19840862
Recombinant organisms for production of industrial products.
Adrio JL, Demain AL., Bioeng Bugs 1(2), 2010
PMID: 21326937
Requirement of de novo synthesis of the OdhI protein in penicillin-induced glutamate production by Corynebacterium glutamicum.
Kim J, Fukuda H, Hirasawa T, Nagahisa K, Nagai K, Wachi M, Shimizu H., Appl Microbiol Biotechnol 86(3), 2010
PMID: 19956942
Analysing overexpression of L-valine biosynthesis genes in pyruvate-dehydrogenase-deficient Corynebacterium glutamicum.
Bartek T, Zönnchen E, Klein B, Gerstmeir R, Makus P, Lang S, Oldiges M., J Ind Microbiol Biotechnol 37(3), 2010
PMID: 20012552
Biotechnological production of enantiomeric pure lactic acid from renewable resources: recent achievements, perspectives, and limits.
Okano K, Tanaka T, Ogino C, Fukuda H, Kondo A., Appl Microbiol Biotechnol 85(3), 2010
PMID: 19826806
The Zur regulon of Corynebacterium glutamicum ATCC 13032.
Schröder J, Jochmann N, Rodionov DA, Tauch A., BMC Genomics 11(), 2010
PMID: 20055984
The transcriptional regulators RamA and RamB are involved in the regulation of glycogen synthesis in Corynebacterium glutamicum.
Seibold GM, Hagmann CT, Schietzel M, Emer D, Auchter M, Schreiner J, Eikmanns BJ., Microbiology 156(pt 4), 2010
PMID: 20056699
Importance of NADPH supply for improved L-valine formation in Corynebacterium glutamicum.
Bartek T, Blombach B, Zönnchen E, Makus P, Lang S, Eikmanns BJ, Oldiges M., Biotechnol Prog 26(2), 2010
PMID: 20014412
Studies on substrate utilisation in L-valine-producing Corynebacterium glutamicum strains deficient in pyruvate dehydrogenase complex.
Bartek T, Rudolf C, Kerssen U, Klein B, Blombach B, Lang S, Eikmanns BJ, Oldiges M., Bioprocess Biosyst Eng 33(7), 2010
PMID: 20204663
Expanding metabolism for total biosynthesis of the nonnatural amino acid L-homoalanine.
Zhang K, Li H, Cho KM, Liao JC., Proc Natl Acad Sci U S A 107(14), 2010
PMID: 20332210
Factors enhancing L-valine production by the growth-limited L-isoleucine auxotrophic strain Corynebacterium glutamicum DeltailvA DeltapanB ilvNM13 (pECKAilvBNC).
Denina I, Paegle L, Prouza M, Holátko J, Pátek M, Nesvera J, Ruklisha M., J Ind Microbiol Biotechnol 37(7), 2010
PMID: 20364396
Bacillus methanolicus pyruvate carboxylase and homoserine dehydrogenase I and II and their roles for L-lysine production from methanol at 50 degrees C.
Brautaset T, Jakobsen ØM, Degnes KF, Netzer R, Naerdal I, Krog A, Dillingham R, Flickinger MC, Ellingsen TE., Appl Microbiol Biotechnol 87(3), 2010
PMID: 20372887
Engineering Corynebacterium glutamicum for isobutanol production.
Smith KM, Cho KM, Liao JC., Appl Microbiol Biotechnol 87(3), 2010
PMID: 20376637
Finding metabolic pathways using atom tracking.
Heath AP, Bennett GN, Kavraki LE., Bioinformatics 26(12), 2010
PMID: 20421197
Evaluation of substrate promiscuity of an L-carbamoyl amino acid amidohydrolase from Geobacillus stearothermophilus CECT43.
Pozo-Dengra J, Martínez-Gómez AI, Martínez-Rodríguez S, Clemente-Jiménez JM, Rodríguez-Vico F, Las Heras-Vázquez FJ., Biotechnol Prog 26(4), 2010
PMID: 20730754
L-Glutamine as a nitrogen source for Corynebacterium glutamicum: derepression of the AmtR regulon and implications for nitrogen sensing.
Rehm N, Georgi T, Hiery E, Degner U, Schmiedl A, Burkovski A, Bott M., Microbiology 156(pt 10), 2010
PMID: 20656783
Synthetic biology guides biofuel production.
Connor MR, Atsumi S., J Biomed Biotechnol 2010(), 2010
PMID: 20827393
Increased synthesis of α-tocopherol, paramylon and tyrosine by Euglena gracilis under conditions of high biomass production.
Rodríguez-Zavala JS, Ortiz-Cruz MA, Mendoza-Hernández G, Moreno-Sánchez R., J Appl Microbiol 109(6), 2010
PMID: 20854454
Metabolic engineering of Corynebacterium glutamicum for 2-ketoisovalerate production.
Krause FS, Blombach B, Eikmanns BJ., Appl Environ Microbiol 76(24), 2010
PMID: 20935122
Developments in nitrile and amide biotransformation processes.
Velankar H, Clarke KG, du Preez R, Cowan DA, Burton SG., Trends Biotechnol 28(11), 2010
PMID: 20832882
Bioengineering of microorganisms for C₃ to C₅ alcohols production.
Mainguet SE, Liao JC., Biotechnol J 5(12), 2010
PMID: 21154669
Direct production of cadaverine from soluble starch using Corynebacterium glutamicum coexpressing alpha-amylase and lysine decarboxylase.
Tateno T, Okada Y, Tsuchidate T, Tanaka T, Fukuda H, Kondo A., Appl Microbiol Biotechnol 82(1), 2009
PMID: 18989633
Acetohydroxyacid synthase, a novel target for improvement of L-lysine production by Corynebacterium glutamicum.
Blombach B, Hans S, Bathe B, Eikmanns BJ., Appl Environ Microbiol 75(2), 2009
PMID: 19047397
Metabolic engineering of the L-valine biosynthesis pathway in Corynebacterium glutamicum using promoter activity modulation.
Holátko J, Elisáková V, Prouza M, Sobotka M, Nesvera J, Pátek M., J Biotechnol 139(3), 2009
PMID: 19121344
Expression and localization of the Corynebacterium glutamicum NCgl1221 protein encoding an L-glutamic acid exporter.
Yao W, Deng X, Liu M, Zheng P, Sun Z, Zhang Y., Microbiol Res 164(6), 2009
PMID: 19233628
A game with many players: control of gdh transcription in Corynebacterium glutamicum.
Hänssler E, Müller T, Palumbo K, Patek M, Brocker M, Krämer R, Burkovski A., J Biotechnol 142(2), 2009
PMID: 19394370
Double deletion of dtsR1 and pyc induce efficient L: -glutamate overproduction in Corynebacterium glutamicum.
Yao W, Deng X, Zhong H, Liu M, Zheng P, Sun Z, Zhang Y., J Ind Microbiol Biotechnol 36(7), 2009
PMID: 19408028
Development of novel cell surface display in Corynebacterium glutamicum using porin.
Tateno T, Hatada K, Tanaka T, Fukuda H, Kondo A., Appl Microbiol Biotechnol 84(4), 2009
PMID: 19430772
Kinetic resolution of aliphatic beta-amino acid amides by beta-aminopeptidases.
Heck T, Seebach D, Osswald S, Ter Wiel MK, Kohler HP, Geueke B., Chembiochem 10(9), 2009
PMID: 19449346
Production of L-phenylalanine from glycerol by a recombinant Escherichia coli.
Khamduang M, Packdibamrung K, Chutmanop J, Chisti Y, Srinophakun P., J Ind Microbiol Biotechnol 36(10), 2009
PMID: 19565282
Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum.
Shinfuku Y, Sorpitiporn N, Sono M, Furusawa C, Hirasawa T, Shimizu H., Microb Cell Fact 8(), 2009
PMID: 19646286
Visualizing post genomics data-sets on customized pathway maps by ProMeTra-aeration-dependent gene expression and metabolism of Corynebacterium glutamicum as an example.
Neuweger H, Persicke M, Albaum SP, Bekel T, Dondrup M, Hüser AT, Winnebald J, Schneider J, Kalinowski J, Goesmann A., BMC Syst Biol 3(), 2009
PMID: 19698148
Production of aromatic compounds in bacteria.
Gosset G., Curr Opin Biotechnol 20(6), 2009
PMID: 19875279
Industrial biotechnology: tools and applications.
Tang WL, Zhao H., Biotechnol J 4(12), 2009
PMID: 19844915
Flux Design: In silico design of cell factories based on correlation of pathway fluxes to desired properties.
Melzer G, Esfandabadi ME, Franco-Lara E, Wittmann C., BMC Syst Biol 3(), 2009
PMID: 20035624
L-tyrosine production by recombinant Escherichia coli: fermentation optimization and recovery.
Patnaik R, Zolandz RR, Green DA, Kraynie DF., Biotechnol Bioeng 99(4), 2008
PMID: 18069696
Corynebacterium glutamicum tailored for high-yield L-valine production.
Blombach B, Schreiner ME, Bartek T, Oldiges M, Eikmanns BJ., Appl Microbiol Biotechnol 79(3), 2008
PMID: 18379776
A putative alpha-helical porin from Corynebacterium glutamicum.
Ziegler K, Benz R, Schulz GE., J Mol Biol 379(3), 2008
PMID: 18462756
Metabolic regulation and overproduction of primary metabolites.
Sanchez S, Demain AL., Microb Biotechnol 1(4), 2008
PMID: 21261849
Response of the cytoplasmic and membrane proteome of Corynebacterium glutamicum ATCC 13032 to pH changes.
Barriuso-Iglesias M, Schluesener D, Barreiro C, Poetsch A, Martín JF., BMC Microbiol 8(), 2008
PMID: 19091079
CoryneRegNet 3.0--an interactive systems biology platform for the analysis of gene regulatory networks in corynebacteria and Escherichia coli.
Baumbach J, Wittkop T, Rademacher K, Rahmann S, Brinkrolf K, Tauch A., J Biotechnol 129(2), 2007
PMID: 17229482
L-tyrosine production by deregulated strains of Escherichia coli.
Lütke-Eversloh T, Stephanopoulos G., Appl Microbiol Biotechnol 75(1), 2007
PMID: 17221195
The IclR-type transcriptional repressor LtbR regulates the expression of leucine and tryptophan biosynthesis genes in the amino acid producer Corynebacterium glutamicum.
Brune I, Jochmann N, Brinkrolf K, Hüser AT, Gerstmeir R, Eikmanns BJ, Kalinowski J, Pühler A, Tauch A., J Bacteriol 189(7), 2007
PMID: 17259312
L-valine production with pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum.
Blombach B, Schreiner ME, Holátko J, Bartek T, Oldiges M, Eikmanns BJ., Appl Environ Microbiol 73(7), 2007
PMID: 17293513
Innovative metabolic pathway design for efficient l-glutamate production by suppressing CO2 emission.
Chinen A, Kozlov YI, Hara Y, Izui H, Yasueda H., J Biosci Bioeng 103(3), 2007
PMID: 17434430
Effect of pyruvate dehydrogenase complex deficiency on L-lysine production with Corynebacterium glutamicum.
Blombach B, Schreiner ME, Moch M, Oldiges M, Eikmanns BJ., Appl Microbiol Biotechnol 76(3), 2007
PMID: 17333167
FarR, a putative regulator of amino acid metabolism in Corynebacterium glutamicum.
Hänssler E, Müller T, Jessberger N, Völzke A, Plassmeier J, Kalinowski J, Krämer R, Burkovski A., Appl Microbiol Biotechnol 76(3), 2007
PMID: 17483938
Increased production of pyruvic acid by Escherichia coli RNase G mutants in combination with cra mutations.
Sakai T, Nakamura N, Umitsuki G, Nagai K, Wachi M., Appl Microbiol Biotechnol 76(1), 2007
PMID: 17483940
Characteristics of methionine production by an engineered Corynebacterium glutamicum strain.
Park SD, Lee JY, Sim SY, Kim Y, Lee HS., Metab Eng 9(4), 2007
PMID: 17604670
Transport of D-[1-14C]-amino acids into Chinese hamster ovary (CHO-K1) cells: implications for use of labeled d-amino acids as molecular imaging agents.
Shikano N, Nakajima S, Kotani T, Ogura M, Sagara J, Iwamura Y, Yoshimoto M, Kubota N, Ishikawa N, Kawai K., Nucl Med Biol 34(6), 2007
PMID: 17707806
Genomics of Actinobacteria: tracing the evolutionary history of an ancient phylum.
Ventura M, Canchaya C, Tauch A, Chandra G, Fitzgerald GF, Chater KF, van Sinderen D., Microbiol Mol Biol Rev 71(3), 2007
PMID: 17804669
Perspectives of biotechnological production of L-tyrosine and its applications.
Lütke-Eversloh T, Santos CN, Stephanopoulos G., Appl Microbiol Biotechnol 77(4), 2007
PMID: 17968539
Systems metabolic engineering of Escherichia coli for L-threonine production.
Lee KH, Park JH, Kim TY, Kim HU, Lee SY., Mol Syst Biol 3(), 2007
PMID: 18059444
Production system for biodegradable polyester polyhydroxybutyrate by Corynebacterium glutamicum.
Jo SJ, Maeda M, Ooi T, Taguchi S., J Biosci Bioeng 102(3), 2006
PMID: 17046539
Determination of soluble and granular inorganic polyphosphate in Corynebacterium glutamicum.
Klauth P, Pallerla SR, Vidaurre D, Ralfs C, Wendisch VF, Schoberth SM., Appl Microbiol Biotechnol 72(5), 2006
PMID: 16977467

37 References

Daten bereitgestellt von Europe PubMed Central.


Lysine-rich gamma-zeins are secreted in transgenic Arabidopsis plants.
Alvarez I, Geli MI, Pimentel E, Ludevid D, Torrent M., Planta 205(3), 1998
PMID: 9640667


D, 1995



GJ, 1992

GJ, 1992

J, 1978

VG, 2003

AA, 2001


K, 2002

U, J Pept Science 3(), 1997

H, 2003

M, 2003
The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.
Kalinowski J, Bathe B, Bartels D, Bischoff N, Bott M, Burkovski A, Dusch N, Eggeling L, Eikmanns BJ, Gaigalat L, Goesmann A, Hartmann M, Huthmacher K, Kramer R, Linke B, McHardy AC, Meyer F, Mockel B, Pfefferle W, Puhler A, Rey DA, Ruckert C, Rupp O, Sahm H, Wendisch VF, Wiegrabe I, Tauch A., J. Biotechnol. 104(1-3), 2003
PMID: 12948626

E, 2003

S, J Gen Appl Microbiol 3(), 1957

W, 1996


O, Org. Process Res. Dev. 6(), 2002


J, Drugs Future 22(), 1997

KM, Biotechnol Lett 14(), 1992

W, 2003

NM, Adv Synth Catal 345(), 2003


H, Eur J Biochem 207(), 2000




J, 2005


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