Time to remission from mild to moderate depressive symptoms: One year results from the EVIDENT-study, an RCT of an internet intervention for depression

Klein JP, Spaeth C, Schroeder J, Meyer B, Greiner W, Hautzinger M, Lutz W, Rose M, Vettorazzi E, Andersson G, Hohagen F, et al. (2017)
Behaviour Research and Therapy 97: 154-162.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Klein, Jan Philipp; Spaeth, Christina; Schroeder, Johanna; Meyer, Bjoern; Greiner, WolfgangUniBi; Hautzinger, Martin; Lutz, Wolfgang; Rose, Matthias; Vettorazzi, Eik; Andersson, Gerhard; Hohagen, Fritz; Moritz, Steffen
Alle
Abstract / Bemerkung
Background: Internet interventions are effective in treating depressive symptoms but few studies conducted a long-term follow-up. The aim of this study was to test the effectiveness of an internet intervention in increasing the remission rate over a twelve months period. Methods: A total of 1013 participants with mild to moderate depressive symptoms were randomized to either care as usual alone or a 12-week internet intervention (Deprexis) plus usual care. Self-rated depression severity (PHQ-9) was assessed regularly over twelve months. Results: Remission rates over time were significantly higher in the intervention group (Cox regression: hazard ratio [HR] 1.31; p = 0.009). The intervention was more effective in the subgroup not taking antidepressant medication (Cox regression: HR 1.88; p < 0.001). PHQ-change from baseline was greater in the intervention group (linear mixed model [LMM]: p < 0.001) with the between-group effect gradually decreasing from d = 0.36 at three months to d = 0.13 at twelve months (LMM: group by time interaction: p < 0.001). Conclusion: This internet intervention can contribute to achieving remission in people with mild to moderate depressive symptoms, especially if they are not on antidepressant medication (Trial Registration: NCT01636752). (C) 2017 Elsevier Ltd. All rights reserved.
Stichworte
Internet intervention; Cognitive behavior therapy; Depression; Remission; Randomized controlled trial; One year follow-up
Erscheinungsjahr
2017
Zeitschriftentitel
Behaviour Research and Therapy
Band
97
Seite(n)
154-162
ISSN
0005-7967
eISSN
1873-622X
Page URI
https://pub.uni-bielefeld.de/record/2916454

Zitieren

Klein JP, Spaeth C, Schroeder J, et al. Time to remission from mild to moderate depressive symptoms: One year results from the EVIDENT-study, an RCT of an internet intervention for depression. Behaviour Research and Therapy. 2017;97:154-162.
Klein, J. P., Spaeth, C., Schroeder, J., Meyer, B., Greiner, W., Hautzinger, M., Lutz, W., et al. (2017). Time to remission from mild to moderate depressive symptoms: One year results from the EVIDENT-study, an RCT of an internet intervention for depression. Behaviour Research and Therapy, 97, 154-162. doi:10.1016/j.brat.2017.07.013
Klein, J. P., Spaeth, C., Schroeder, J., Meyer, B., Greiner, W., Hautzinger, M., Lutz, W., Rose, M., Vettorazzi, E., Andersson, G., et al. (2017). Time to remission from mild to moderate depressive symptoms: One year results from the EVIDENT-study, an RCT of an internet intervention for depression. Behaviour Research and Therapy 97, 154-162.
Klein, J.P., et al., 2017. Time to remission from mild to moderate depressive symptoms: One year results from the EVIDENT-study, an RCT of an internet intervention for depression. Behaviour Research and Therapy, 97, p 154-162.
J.P. Klein, et al., “Time to remission from mild to moderate depressive symptoms: One year results from the EVIDENT-study, an RCT of an internet intervention for depression”, Behaviour Research and Therapy, vol. 97, 2017, pp. 154-162.
Klein, J.P., Spaeth, C., Schroeder, J., Meyer, B., Greiner, W., Hautzinger, M., Lutz, W., Rose, M., Vettorazzi, E., Andersson, G., Hohagen, F., Moritz, S., Berger, T.: Time to remission from mild to moderate depressive symptoms: One year results from the EVIDENT-study, an RCT of an internet intervention for depression. Behaviour Research and Therapy. 97, 154-162 (2017).
Klein, Jan Philipp, Spaeth, Christina, Schroeder, Johanna, Meyer, Bjoern, Greiner, Wolfgang, Hautzinger, Martin, Lutz, Wolfgang, Rose, Matthias, Vettorazzi, Eik, Andersson, Gerhard, Hohagen, Fritz, Moritz, Steffen, and Berger, Thomas. “Time to remission from mild to moderate depressive symptoms: One year results from the EVIDENT-study, an RCT of an internet intervention for depression”. Behaviour Research and Therapy 97 (2017): 154-162.

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