Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015

Feigin VL, Abajobir AA, Abate KH, Abd-Allah F, Abdulle AM, Abera SF, Abyu GY, Ahmed MB, Aichour AN, Aichour I, Aichour MTE, et al. (2017)
LANCET NEUROLOGY 16(11): 877-897.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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DOI
Autor*in
Feigin, Valery L.; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abd-Allah, Foad; Abdulle, Abdishakur M.; Abera, Semaw Ferede; Abyu, Gebre Yitayih; Ahmed, Muktar Beshir; Aichour, Amani Nidhal; Aichour, Ibtihel; Aichour, Miloud Taki Eddine; Akinyemi, Rufus Olusola
Alle
Einrichtung
Fakultät für Gesundheitswissenschaften > AG 2 Bevölkerungsmedizin und Versorgungsforschung
Abstract / Bemerkung
Background Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions. In this systematic analysis, we quantified the global disease burden due to neurological disorders in 2015 and its relationship with country development level. Methods We estimated global and country-specific prevalence, mortality, disability-adjusted life-years (DALYs), years of life lost (YLLs), and years lived with disability (YLDs) for various neurological disorders that in the GBD classification have been previously spread across multiple disease groupings. The more inclusive grouping of neurological disorders included stroke, meningitis, encephalitis, tetanus, Alzheimer's disease and other dementias, Parkinson's disease, epilepsy, multiple sclerosis, motor neuron disease, migraine, tension-type headache, medication overuse headache, brain and nervous system cancers, and a residual category of other neurological disorders. We also analysed results based on the Socio-demographic Index (SDI), a compound measure of income per capita, education, and fertility, to identify patterns associated with development and how countries fare against expected outcomes relative to their level of development. Findings Neurological disorders ranked as the leading cause group of DALYs in 2015 (250.7 [95% uncertainty interval (UI) 229.1 to 274.7] million, comprising 10.2% of global DALYs) and the second-leading cause group of deaths (9.4 [9.1 to 9.7] million], comprising 16.8% of global deaths). The most prevalent neurological disorders were tensiontype headache (1505 9 [UI 1337.3 to 1681.6 million cases]), migraine (958.8 [872.1 to 1055.6] million), medication overuse headache (58.5 [50.8 to 67.4 million]), and Alzheimer's disease and other dementias (46.0 [40.2 to 52.7 million]). Between 1990 and 2015, the number of deaths from neurological disorders increased by 36.7%, and the number of DALYs by 7.4%. These increases occurred despite decreases in age-standardised rates of death and DALYs of 26.1% and 29.7%, respectively; stroke and communicable neurological disorders were responsible for most of these decreases. Communicable neurological disorders were the largest cause of DALYs in countries with low SDI. Stroke rates were highest at middle levels of SDI and lowest at the highest SDI. Most of the changes in DALY rates of neurological disorders with development were driven by changes in YLLs. Interpretation Neurological disorders are an important cause of disability and death worldwide. Globally, the burden of neurological disorders has increased substantially over the past 25 years because of expanding population numbers and ageing, despite substantial decreases in mortality rates from stroke and communicable neurological disorders. The number of patients who will need care by clinicians with expertise in neurological conditions will continue to grow in coming decades. Policy makers and health-care providers should be aware of these trends to provide adequate services.
Erscheinungsjahr
2017
Zeitschriftentitel
LANCET NEUROLOGY
Band
16
Ausgabe
11
Seite(n)
877-897
Urheberrecht / Lizenzen
Creative Commons Namensnennung 4.0 International Public License (CC-BY 4.0)
ISSN
1474-4422
eISSN
1474-4465
Page URI
https://pub.uni-bielefeld.de/record/2916442

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Feigin VL, Abajobir AA, Abate KH, et al. Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. LANCET NEUROLOGY. 2017;16(11):877-897.
Feigin, V. L., Abajobir, A. A., Abate, K. H., Abd-Allah, F., Abdulle, A. M., Abera, S. F., Abyu, G. Y., et al. (2017). Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. LANCET NEUROLOGY, 16(11), 877-897. doi:10.1016/S1474-4422(17)30299-5
Feigin, Valery L., Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abd-Allah, Foad, Abdulle, Abdishakur M., Abera, Semaw Ferede, Abyu, Gebre Yitayih, et al. 2017. “Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015”. LANCET NEUROLOGY 16 (11): 877-897.
Feigin, V. L., Abajobir, A. A., Abate, K. H., Abd-Allah, F., Abdulle, A. M., Abera, S. F., Abyu, G. Y., Ahmed, M. B., Aichour, A. N., Aichour, I., et al. (2017). Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. LANCET NEUROLOGY 16, 877-897.
Feigin, V.L., et al., 2017. Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. LANCET NEUROLOGY, 16(11), p 877-897.
V.L. Feigin, et al., “Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015”, LANCET NEUROLOGY, vol. 16, 2017, pp. 877-897.
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Ray, Ellenbogen, Richard G., Eskandarieh, Sharareh, Farvid, Maryam S., Fereshtehnejad, Seyed-Mohammad, Fischer, Florian, Foreman, Kyle J., Geleijnse, Johanna M., Gillum, Richard F., Giussani, Giorgia, Goldberg, Ellen M., Gona, Philimon N., Goulart, Alessandra Carvalho, Gugnani, Harish Chander, Gupta, Rahul, Gupta, Rajeev, Hachinski, Vladimir, Hamadeh, Randah Ribhi, Hambisa, Mitiku, Hankey, Graeme J., Hareri, Habtamu Abera, Havmoeller, Rasmus, Hay, Simon I., Heydarpour, Pouria, Hotez, Peter J., Jakovljevic, Mihajlo (Michael) B., Javanbakht, Mehdi, Jeemon, Panniyammakal, Jonas, Jost B., Kalkonde, Yogeshwar, Kandel, Amit, Karch, Andre, Kasaeian, Amir, Kastor, Anshul, Keiyoro, Peter Njenga, Khader, Yousef Saleh, Khalil, Ibrahim A., Khan, Ejaz Ahmad, Khang, Young-Ho, Khoja, Abdullah TawfihAbdullah, Khubchandani, Jagdish, Kulkarni, Chanda, Kim, Daniel, Kim, Yun Jin, Kivimaki, Mika, Kokubo, Yoshihiro, Kosen, Soewarta, Kravchenko, Michael, Krishnamurthi, Rita Vanmala, Defo, Barthelemy Kuate, Kumar, G. Anil, Kumar, Rashmi, Kyu, Hmwe H., Larsson, Anders, Lavados, Pablo M., Li, Yongmei, Liang, Xiaofeng, Liben, Misgan Legesse, Lo, Warren D., Logroscino, Giancarlo, Lotufo, Paulo A., Loy, Clement T., Mackay, Mark T., Abd El Razek, Hassan Magdy, Abd El Razek, Mohammed Magdy, Majeed, Azeem, Malekzadeh, Reza, Manhertz, Treh, Mantovani, Lorenzo G., Massano, Joao, Mazidi, Mohsen, McAlinden, Colm, Mehata, Suresh, Mehndiratta, Man Mohan, Memish, Ziad A., Mendoza, Walter, Mengistie, Mubarek Abera, Mensah, George A., Meretoja, Atte, Mezgebe, Haftay Berhane, Miller, Ted R., Mishra, Shiva Raj, Ibrahim, Norlinah Mohamed, Mohammadi, Alireza, Mohammed, Kedir Endris, Mohammed, Shafiu, Mokdad, Ali H., Moradi-Lakeh, Maziar, Velasquez, Ilais Moreno, Musa, Kamarul Imran, Naghavi, Mohsen, Ngunjiri, Josephine Wanjiku, Cuong Tat Nguyen, Cuong Tat Nguyen, Nguyen, Grant, Quyen Le Nguyen, Quyen Le Nguyen, Trang Huyen Nguyen, Trang Huyen Nguyen, Nichols, Emma, Ningrum, Dina NurAnggraini, Vuong Minh Nong, Vuong Minh Nong, Norrving, Bo, Noubiap, Jean Jacques N., Ogbo, Felix Akpojene, Owolabi, Mayowa O., Pandian, Jeyaraj D., Parmar, Priyakumari Ganesh, Pereira, David M., Petzold, Max, Phillips, Michael Robert, Piradov, Michael A., Poulton, Richie G., Pourmalek, Farshad, Qorbani, Mostafa, Rafay, Anwar, Rahman, Mahfuzar, Rahman, Mohammad HifzUr, Rai, Rajesh Kumar, Rajsic, Sasa, Ranta, Annemarei, Rawaf, Salman, Renzaho, Andre M. N., Rezai, Mohammad Sadegh, Roth, Gregory A., Roshandel, Gholamreza, Rubagotti, Enrico, Sachdev, Perminder, Safiri, Saeid, Sahathevan, Ramesh, Sahraian, Mohammad Ali, Samy, Abdallah M., Santalucia, Paula, Santos, Itamar S., Sartorius, Benn, Satpathy, Maheswar, Sawhney, Monika, Saylan, Mete I., Sepanlou, Sadaf G., Shaikh, Masood Ali, Shakir, Raad, Shamsizadeh, Morteza, Sheth, Kevin N., Shigematsu, Mika, Shoman, Haitham, Silva, Diego AugustoSantos, Smith, Mari, Sobngwi, Eugene, Sposato, Luciano A., Stanaway, Jeffrey D., Stein, Dan J., Steiner, Timothy J., Stovner, Lars Jacob, Abdulkader, Rizwan Suliankatchi, Szoeke, Cassandra E. 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Jayaraj RL, Azimullah S, Beiram R, Jalal FY, Rosenberg GA., J Neuroinflammation 16(1), 2019
PMID: 31291966
Immunological Aspects of Approved MS Therapeutics.
Rommer PS, Milo R, Han MH, Satyanarayan S, Sellner J, Hauer L, Illes Z, Warnke C, Laurent S, Weber MS, Zhang Y, Stuve O., Front Immunol 10(), 2019
PMID: 31354720
Network Meta-Analysis of Calcitonin Gene-Related Peptide Receptor Antagonists for the Acute Treatment of Migraine.
Xu F, Sun W., Front Pharmacol 10(), 2019
PMID: 31354502
The Anti-Inflammatory Effect of Sulforaphane in Mice with Experimental Autoimmune Encephalomyelitis.
Yoo IH, Kim MJ, Kim J, Sung JJ, Park ST, Ahn SW., J Korean Med Sci 34(28), 2019
PMID: 31327180
Re-thinking the Etiological Framework of Neurodegeneration.
Castillo X, Castro-Obregón S, Gutiérrez-Becker B, Gutiérrez-Ospina G, Karalis N, Khalil AA, Lopez-Noguerola JS, Rodríguez LL, Martínez-Martínez E, Perez-Cruz C, Pérez-Velázquez J, Piña AL, Rubio K, García HPS, Syeda T, Vanoye-Carlo A, Villringer A, Winek K, Zille M., Front Neurosci 13(), 2019
PMID: 31396030
Multiple Sclerosis.
Reich DS, Lucchinetti CF, Calabresi PA., N Engl J Med 378(2), 2018
PMID: 29320652
Morphometric changes over the whole brain in caffeine-containing combination-analgesic-overuse headache.
Chen X, Chen Z, Dong Z, Liu M, Yu S., Mol Pain 14(), 2018
PMID: 29877133
Current understanding of meningeal and cerebral vascular function underlying migraine headache.
Levy D, Labastida-Ramirez A, MaassenVanDenBrink A., Cephalalgia (), 2018
PMID: 29929378
Heme Oxygenase-1: Clinical Relevance in Ischemic Stroke.
Bereczki D, Balla J, Bereczki D., Curr Pharm Des 24(20), 2018
PMID: 30014798
Parkinson Matters.
Darweesh SKL, Raphael KG, Brundin P, Matthews H, Wyse RK, Chen H, Bloem BR., J Parkinsons Dis 8(4), 2018
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The Emerging Evidence of the Parkinson Pandemic.
Dorsey ER, Sherer T, Okun MS, Bloem BR., J Parkinsons Dis 8(s1), 2018
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Mapping of global scientific research in comorbidity and multimorbidity: A cross-sectional analysis.
Catalá-López F, Alonso-Arroyo A, Page MJ, Hutton B, Tabarés-Seisdedos R, Aleixandre-Benavent R., PLoS One 13(1), 2018
PMID: 29298301
Neuropathology correlates of cognitive assessments.
Brett FM, Kearney H., Ir J Med Sci 187(3), 2018
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Study of Stroke Incidence in the Aseer Region, Southwestern Saudi Arabia.
Alhazzani AA, Mahfouz AA, Abolyazid AY, Awadalla NJ, Aftab R, Faraheen A, Khalil SN., Int J Environ Res Public Health 15(2), 2018
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Air Pollution and Stroke.
Lee KK, Miller MR, Shah ASV., J Stroke 20(1), 2018
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Innate immunity and cellular senescence: The good and the bad in the developmental and aged brain.
Santoro A, Spinelli CC, Martucciello S, Nori SL, Capunzo M, Puca AA, Ciaglia E., J Leukoc Biol 103(3), 2018
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The headache under-response to treatment (HURT) questionnaire, an outcome measure to guide follow-up in primary care: development, psychometric evaluation and assessment of utility.
Steiner TJ, Buse DC, Al Jumah M, Westergaard ML, Jensen RH, Reed ML, Prilipko L, Mennini FS, Láinez MJA, Ravishankar K, Sakai F, Yu SY, Fontebasso M, Al Khathami A, MacGregor EA, Antonaci F, Tassorelli C, Lipton RB, Lifting The Burden: The Global Campaign against Headache., J Headache Pain 19(1), 2018
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Developing DNA methylation-based diagnostic biomarkers.
Kim H, Wang X, Jin P., J Genet Genomics 45(2), 2018
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Warning SINEs: Alu elements, evolution of the human brain, and the spectrum of neurological disease.
Larsen PA, Hunnicutt KE, Larsen RJ, Yoder AD, Saunders AM., Chromosome Res 26(1-2), 2018
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Mediterranean Diet in Preventing Neurodegenerative Diseases.
Gardener H, Caunca MR., Curr Nutr Rep 7(1), 2018
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Modulation of miRNA expression in aged rat hippocampus by buttermilk and krill oil.
Crespo MC, Tomé-Carneiro J, Gómez-Coronado D, Burgos-Ramos E, García-Serrano A, Martín-Hernández R, Baliyan S, Fontecha J, Venero C, Dávalos A, Visioli F., Sci Rep 8(1), 2018
PMID: 29507352
Association Between MicroRNAs Polymorphisms and Risk of Ischemic Stroke: A Meta-Analysis in Chinese Individuals.
Li CX, Weng H, Zheng J, Feng ZH, Ou JL, Liao WJ., Front Aging Neurosci 10(), 2018
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Commentary: Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.
Karikari TK, Charway-Felli A, Höglund K, Blennow K, Zetterberg H., Front Neurol 9(), 2018
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Neuroanesthesiology Update.
Pasternak JJ, Lanier WL., J Neurosurg Anesthesiol 30(2), 2018
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Targeted CGRP Small Molecule Antagonists for Acute Migraine Therapy.
Holland PR, Goadsby PJ., Neurotherapeutics 15(2), 2018
PMID: 29556965
Have there been improvements in Alzheimer's disease drug discovery over the past 5 years?
Cacabelos R., Expert Opin Drug Discov 13(6), 2018
PMID: 29607687
The Evidence for the Role of Nutraceuticals in the Management of Pediatric Migraine: a Review.
Orr SL., Curr Pain Headache Rep 22(5), 2018
PMID: 29619575
Is Migraine Primarily a Metaboloendocrine Disorder?
Rainero I, Govone F, Gai A, Vacca A, Rubino E., Curr Pain Headache Rep 22(5), 2018
PMID: 29619630
Teleneurology and mobile technologies: the future of neurological care.
Dorsey ER, Glidden AM, Holloway MR, Birbeck GL, Schwamm LH., Nat Rev Neurol 14(5), 2018
PMID: 29623949
The primary prevention of epilepsy: A report of the Prevention Task Force of the International League Against Epilepsy.
Thurman DJ, Begley CE, Carpio A, Helmers S, Hesdorffer DC, Mu J, Touré K, Parko KL, Newton CR., Epilepsia 59(5), 2018
PMID: 29637551
The Promise of Telemedicine for Movement Disorders: an Interdisciplinary Approach.
Ben-Pazi H, Browne P, Chan P, Cubo E, Guttman M, Hassan A, Hatcher-Martin J, Mari Z, Moukheiber E, Okubadejo NU, Shalash A, International Parkinson and Movement Disorder Society Telemedicine Task Force., Curr Neurol Neurosci Rep 18(5), 2018
PMID: 29654523
Rs4612666 Polymorphism of the NLRP3 Gene Is Associated with the Occurrence of Large Artery Atherosclerotic Ischemic Strokes and Microembolic Signals.
Cheng L, Yin R, Yang S, Pan X, Ma A., Biomed Res Int 2018(), 2018
PMID: 29850543
Towards earlier diagnosis and treatment of disorders of the brain.
Di Luca M, Nutt D, Oertel W, Boyer P, Jaarsma J, Destrebecq F, Esposito G, Quoidbach V., Bull World Health Organ 96(5), 2018
PMID: 29875510
Cross-cultural adaptation of the stroke self-efficacy questionnaire - Denmark (SSEQ-DK).
Kristensen LQ, Pallesen H., Top Stroke Rehabil 25(6), 2018
PMID: 29726803
Nongenetic Optical Methods for Measuring and Modulating Neuronal Response.
Zimmerman JF, Tian B., ACS Nano 12(5), 2018
PMID: 29727159
In Hospital Stroke Mortality: Rates and Determinants in Southwestern Saudi Arabia.
Alhazzani AA, Mahfouz AA, Abolyazid AY, Awadalla NJ, Katramiz K, Faraheen A, Khalil SN, Aftab R., Int J Environ Res Public Health 15(5), 2018
PMID: 29735898
Association of epilepsy and asthma: a population-based retrospective cohort study.
Chiang KL, Kuo FC, Lee JY, Huang CY., PeerJ 6(), 2018
PMID: 29796346
Common Carotid Artery Diameter and Risk of Cardiovascular Events and Mortality: Pooled Analyses of Four Cohort Studies.
Sedaghat S, van Sloten TT, Laurent S, London GM, Pannier B, Kavousi M, Mattace-Raso F, Franco OH, Boutouyrie P, Ikram MA, Stehouwer CDA., Hypertension 72(1), 2018
PMID: 29785959
Design and Efficacy of Nanogels Formulations for Intranasal Administration.
Aderibigbe BA, Naki T., Molecules 23(6), 2018
PMID: 29789506
Evaluation of gray matter perfusion in episodic migraine using voxel-wise comparison of 3D pseudo-continuous arterial spin labeling.
Chen Z, Chen X, Liu M, Liu M, Ma L, Yu S., J Headache Pain 19(1), 2018
PMID: 29796865
Acupuncture as prophylaxis for chronic migraine: a protocol for a single-blinded, double-dummy randomised controlled trial.
Liu L, Zhao LP, Zhang CS, Zeng L, Wang K, Zhao J, Wang L, Jing X, Li B., BMJ Open 8(5), 2018
PMID: 29858418
Chronic Headache Due to Overuse of Analgesics and Anti-Migraine Agents.
Diener HC, Holle D, Dresler T, Gaul C., Dtsch Arztebl Int 115(22), 2018
PMID: 29932046
Detection of Glycan Shedding in the Blood: New Class of Multiple Sclerosis Biomarkers?
DellaValle B, Manresa-Arraut A, Hasseldam H, Stensballe A, Rungby J, Larsen A, Hempel C., Front Immunol 9(), 2018
PMID: 29915593
Multiple Sclerosis in the Asia Pacific Region: A Systematic Review of a Neglected Neurological Disease.
Cheong WL, Mohan D, Warren N, Reidpath DD., Front Neurol 9(), 2018
PMID: 29937752
Targeting vascular inflammation in ischemic stroke: Recent developments on novel immunomodulatory approaches.
Shekhar S, Cunningham MW, Pabbidi MR, Wang S, Booz GW, Fan F., Eur J Pharmacol 833(), 2018
PMID: 29935175
Alzheimer's disease master regulators analysis: search for potential molecular targets and drug repositioning candidates.
Vargas DM, De Bastiani MA, Zimmer ER, Klamt F., Alzheimers Res Ther 10(1), 2018
PMID: 29935546
Assessment of components included in published societal perspective or QALY outcome economic analyses for antiepileptic drug treatment in chronic epilepsy.
Roberts MH, Takeda MY, Kindilien S, Barqawi YK, Borrego ME., Expert Rev Pharmacoecon Outcomes Res 18(5), 2018
PMID: 29911955
Unlocking Human Brain Metabolism by Genome-Scale and Multiomics Metabolic Models: Relevance for Neurology Research, Health, and Disease.
Sertbas M, Ulgen KO., OMICS 22(7), 2018
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Parkinsonian Tremor Detection from Subthalamic Nucleus Local Field Potentials for Closed-Loop Deep Brain Stimulation.
Shah SA, Tinkhauser G, Chen CC, Little S, Brown P., Conf Proc IEEE Eng Med Biol Soc 2018(), 2018
PMID: 30440871
Air pollution: A silent common killer for stroke and dementia.
Azarpazhooh MR, Hachinski V., Int J Stroke 13(7), 2018
PMID: 29969079
Associations of childhood socioeconomic status with mid-life and late-life cognition in Chinese middle-aged and older population based on a 5-year period cohort study.
Sha T, Yan Y, Cheng W., Int J Geriatr Psychiatry 33(10), 2018
PMID: 29971839
Neurology outreach clinic for Huntington disease in Peru: Lessons for neurodegenerative diseases.
Vishnevetsky A, Illanes-Manrique M, Inca-Martinez M, Milla-Neyra K, Sarapura-Castro E, Mazzetti P, Cornejo-Olivas M., Neurology 91(6), 2018
PMID: 29980636
Chronic and intermittent administration of systemic nitroglycerin in the rat induces an increase in the gene expression of CGRP in central areas: potential contribution to pain processing.
Greco R, Demartini C, Zanaboni AM, Tassorelli C., J Headache Pain 19(1), 2018
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Emerging Treatments in Episodic Migraine.
Grimsrud KW, Halker Singh RB., Curr Pain Headache Rep 22(9), 2018
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The Epidemiological Characteristics of Stroke in Hunan Province, China.
He W, Liu Y, Feng J, Huang Q, Xu J, Liu X, Yu C, Zhu W, Wang T, Jin D, Liu H, Huang Y, Chen B., Front Neurol 9(), 2018
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The Therapeutic Potential of Metformin in Neurodegenerative Diseases.
Rotermund C, Machetanz G, Fitzgerald JC., Front Endocrinol (Lausanne) 9(), 2018
PMID: 30072954
TRP Channels as Potential Targets for Sex-Related Differences in Migraine Pain.
Artero-Morales M, González-Rodríguez S, Ferrer-Montiel A., Front Mol Biosci 5(), 2018
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The Growing Incidence of Bullous Pemphigoid: Overview and Potential Explanations.
Kridin K, Ludwig RJ., Front Med (Lausanne) 5(), 2018
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The World Bank & financing tuberculosis control, 1986-2017
Rahi M, Fernandes G, Winters J, Sridhar D., 2018
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Projections of prevalence, lifetime risk, and life expectancy of Parkinson's disease (2010-2030) in France.
Wanneveich M, Moisan F, Jacqmin-Gadda H, Elbaz A, Joly P., Mov Disord 33(9), 2018
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Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer's Disease.
Piemontese L, Vitucci G, Catto M, Laghezza A, Perna FM, Rullo M, Loiodice F, Capriati V, Solfrizzo M., Molecules 23(9), 2018
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Evaluation of Galcanezumab for the Prevention of Episodic Migraine: The EVOLVE-1 Randomized Clinical Trial.
Stauffer VL, Dodick DW, Zhang Q, Carter JN, Ailani J, Conley RR., JAMA Neurol 75(9), 2018
PMID: 29813147
Paediatric migraine: evidence-based management and future directions.
Orr SL, Kabbouche MA, O'Brien HL, Kacperski J, Powers SW, Hershey AD., Nat Rev Neurol 14(9), 2018
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Adherence to the dietary approaches to stop hypertension diet and risk of stroke: A meta-analysis of prospective studies.
Feng Q, Fan S, Wu Y, Zhou D, Zhao R, Liu M, Song Y., Medicine (Baltimore) 97(38), 2018
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Illuminating basal ganglia and beyond in Parkinson's disease.
Vaillancourt DE, Lehericy S., Mov Disord 33(9), 2018
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Myofascial trigger points in migraine and tension-type headache.
Do TP, Heldarskard GF, Kolding LT, Hvedstrup J, Schytz HW., J Headache Pain 19(1), 2018
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Gut-Brain Psychology: Rethinking Psychology From the Microbiota-Gut-Brain Axis.
Liang S, Wu X, Jin F., Front Integr Neurosci 12(), 2018
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Costs, outcome and cost-effectiveness of neurocritical care: a multi-center observational study.
Raj R, Bendel S, Reinikainen M, Hoppu S, Laitio R, Ala-Kokko T, Curtze S, Skrifvars MB., Crit Care 22(1), 2018
PMID: 30236140
Association of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline: A Study Using Optical Coherence Tomography.
Ko F, Muthy ZA, Gallacher J, Sudlow C, Rees G, Yang Q, Keane PA, Petzold A, Khaw PT, Reisman C, Strouthidis NG, Foster PJ, Patel PJ, UK Biobank Eye & Vision Consortium., JAMA Neurol 75(10), 2018
PMID: 29946685
Intranasal Lidocaine for Acute Management of Primary Headaches: A Systematic Review.
Dagenais R, Zed PJ., Pharmacotherapy 38(10), 2018
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Antioxidants and risk of dementia: recent insights and future opportunities.
Koch M, Dhana K, Jensen MK., Curr Opin Lipidol 29(5), 2018
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Rapidly Progressive Dementia in the Outpatient Clinic: More Than Prions.
Day GS, Musiek ES, Morris JC., Alzheimer Dis Assoc Disord 32(4), 2018
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The shifting burden of neurosurgical disease: Vietnam and the middle-income nations.
Carr C, Kahn L, Mathkour M, Biro E, Bui CJ, Dumont AS., Neurosurg Focus 45(4), 2018
PMID: 30269588
Profile of Patients from a Neurology Registry in Resource-Poor Rural Northwest India.
Bhardwaj A, Sharma A, Kumar G, Angra M, Bhardwaj SS, Raina SK, Sharma S, Sharma P., J Neurosci Rural Pract 9(4), 2018
PMID: 30271035
Global, regional, and national burden of Parkinson's disease, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.
GBD 2016 Parkinson's Disease Collaborators., Lancet Neurol 17(11), 2018
PMID: 30287051
Ocular motor cranial nerve palsy and increased risk of stroke in the general population.
Park SJ, Yang HK, Byun SJ, Park KH, Hwang JM., PLoS One 13(10), 2018
PMID: 30321220
Serum Vitamin D Status in a Group of Migraine Patients Compared With Healthy Controls: A Case-Control Study.
Togha M, Razeghi Jahromi S, Ghorbani Z, Martami F, Seifishahpar M., Headache 58(10), 2018
PMID: 30341768
100% Response Rate to Galcanezumab in Patients With Episodic Migraine: A Post Hoc Analysis of the Results From Phase 3, Randomized, Double-Blind, Placebo-Controlled EVOLVE-1 and EVOLVE-2 Studies.
Rosen N, Pearlman E, Ruff D, Day K, Jim Nagy A., Headache 58(9), 2018
PMID: 30341990
CNS infection and immune privilege.
Forrester JV, McMenamin PG, Dando SJ., Nat Rev Neurosci 19(11), 2018
PMID: 30310148
Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
GBD 2017 Disease and Injury Incidence and Prevalence Collaborators., Lancet 392(10159), 2018
PMID: 30496104
Intracranial artery stenosis magnetic resonance imaging aetiology and progression study: Rationale and design.
Han Y, Qiao H, Chen S, Jing J, Pan Y, Li D, Liu Y, Meng X, Wang Y, Zhao X, ICASMAP investigators., Brain Behav 8(12), 2018
PMID: 30456898
Exercise-Induced Change in Plasma IL-12p70 Is Linked to Migraine Prevention and Anxiolytic Effects in Treatment-Naïve Women: A Randomized Controlled Trial.
Oliveira AB, Bachi ALL, Ribeiro RT, Mello MT, Vaisberg M, Peres MFP., Neuroimmunomodulation 24(6), 2017
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CGRP - The Next Frontier for Migraine.
Hershey AD., N Engl J Med 377(22), 2017
PMID: 29171812
Implementing Evidence-Based Practices for Acute Stroke Care in Low- and Middle-Income Countries.
Khatib R, Jawaada AM, Arevalo YA, Hamed HK, Mohammed SH, Huffman MD., Curr Atheroscler Rep 19(12), 2017
PMID: 29119348
Headache in Resource-Limited Settings.
Woldeamanuel YW., Curr Pain Headache Rep 21(12), 2017
PMID: 29143899
Hippocampal Neurodegenerative Pathology in Post-stroke Dementia Compared to Other Dementias and Aging Controls.
Akinyemi RO, Allan LM, Oakley A, Kalaria RN., Front Neurosci 11(), 2017
PMID: 29311794
Burden of neurodevelopmental disorders in low and middle-income countries: A systematic review and meta-analysis.
Bitta M, Kariuki SM, Abubakar A, Newton CRJC., Wellcome Open Res 2(), 2017
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