PUB - Publikationen an der Universität Bielefeld

Escherichia coli (STEC) serotype O104 outbreak causing haemolytic syndrome (HUS) in Germany and France.
Rubino S, Cappuccinelli P, Kelvin DJ., J Infect Dev Ctries 5(6), 2011
PMID: 21727641

[The 2011 HUS epidemic in Germany. Challenges for disease control: what should be improved?].
Krause G, Frank C, Gilsdorf A, Mielke M, Schaade L, Stark K, Burger R., Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56(1), 2013
PMID: 23275957

Experiences from the Shiga toxin-producing Escherichia coli O104:H4 outbreak in Germany and research needs in the field, Berlin, 28–29 November 2011
Stark K, Bauerfeind R, Bernard H, Eckmanns T, Ethelberg S, Flieger A., 2012

Outbreak of Shiga toxin-producing Escherichia coli (STEC) O104:H4 infection in Germany causes a paradigm shift with regard to human pathogenicity of STEC strains.
Beutin L, Martin A., J. Food Prot. 75(2), 2012
PMID: 22289607

Bevorzugte report items für systematischeÜbersichten und meta-analysen: das PRISMA-statement
Ziegler A, Antes G, König I., 2011

Genomic comparison of Escherichia coli O104:H4 isolates from 2009 and 2011 reveals plasmid, and prophage heterogeneity, including shiga toxin encoding phage stx2.
Ahmed SA, Awosika J, Baldwin C, Bishop-Lilly KA, Biswas B, Broomall S, Chain PS, Chertkov O, Chokoshvili O, Coyne S, Davenport K, Detter JC, Dorman W, Erkkila TH, Folster JP, Frey KG, George M, Gleasner C, Henry M, Hill KK, Hubbard K, Insalaco J, Johnson S, Kitzmiller A, Krepps M, Lo CC, Luu T, McNew LA, Minogue T, Munk CA, Osborne B, Patel M, Reitenga KG, Rosenzweig CN, Shea A, Shen X, Strockbine N, Tarr C, Teshima H, van Gieson E, Verratti K, Wolcott M, Xie G, Sozhamannan S, Gibbons HS; Threat Characterization Consortium., PLoS ONE 7(11), 2012
PMID: 23133618

An increased pulsatility index in transcranial Doppler sonography is associated with Shiga-toxin-related encephalopathy in hemolytic uremic syndrome.
Albers JM, Pavenstaedt H, Dlugos C, Lebiedz P, Ringelstein EB, Dittrich R, Ritter MA., Cerebrovasc. Dis. 33(4), 2012
PMID: 22456427

Timeliness of surveillance during outbreak of Shiga Toxin-producing Escherichia coli infection, Germany, 2011.
Altmann M, Spode A, Altmann D, Wadl M, Benzler J, Eckmanns T, Krause G, An der Heiden M., Emerging Infect. Dis. 17(10), 2011
PMID: 22000368

[Hemolytic uremic syndrome following EHEC infection].
Artunc F, Amann K, Haap M., Dtsch. Med. Wochenschr. 136(38), 2011
PMID: 21928172

Update on the ongoing outbreak of haemolytic uraemic syndrome due to Shiga toxin-producing Escherichia coli (STEC) serotype O104, Germany, May 2011.
Askar M, Faber MS, Frank C, Bernard H, Gilsdorf A, Fruth A, Prager R, Hohle M, Suess T, Wadl M, Krause G, Stark K, Werber D., Euro Surveill. 16(22), 2011
PMID: 21663710

EHEC/EAEC O104:H4 strain linked with the 2011 German outbreak of haemolytic uremic syndrome enters into the viable but non-culturable state in response to various stresses and resuscitates upon stress relief.
Aurass P, Prager R, Flieger A., Environ. Microbiol. 13(12), 2011
PMID: 21951606

Serological evidence of asymptomatic infections during Escherichia coli O104:H4 outbreak in Germany in 2011.
Balabanova Y, Klar S, Delere Y, Wilking H, Faber MS, Lassen SG, Gilsdorf A, Dupke S, Nitschke M, Sayk F, Grunow R, Krause G., PLoS ONE 8(9), 2013
PMID: 24039858

Shiga toxin-producing E. coli O104:H4 outbreak 2011 in Germany: radiological features of enterohemorrhagic colitis.
Bannas P, Fraedrich K, Treszl A, Bley TA, Herrmann J, Habermann CR, Derlin T, Henes FO, Wenzel U, Adam G, Yamamura J., Rofo 185(5), 2013
PMID: 23440645

Neurological involvement in children with E. coli O104:H4-induced hemolytic uremic syndrome.
Bauer A, Loos S, Wehrmann C, Horstmann D, Donnerstag F, Lemke J, Hillebrand G, Lobel U, Pape L, Haffner D, Bindt C, Ahlenstiel T, Melk A, Lehnhardt A, Kemper MJ, Oh J, Hartmann H., Pediatr. Nephrol. 29(9), 2014
PMID: 24664191

Shiga toxin-producing Escherichia coli strains from cattle as a source of the Stx2a bacteriophages present in enteroaggregative Escherichia coli O104:H4 strains.
Beutin L, Hammerl JA, Reetz J, Strauch E., Int. J. Med. Microbiol. 303(8), 2013
PMID: 24012149

Effects of antibiotics on Shiga toxin 2 production and bacteriophage induction by epidemic Escherichia coli O104:H4 strain.
Bielaszewska M, Idelevich EA, Zhang W, Bauwens A, Schaumburg F, Mellmann A, Peters G, Karch H., Antimicrob. Agents Chemother. 56(6), 2012
PMID: 22391549

Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study.
Bielaszewska M, Mellmann A, Zhang W, Kock R, Fruth A, Bauwens A, Peters G, Karch H., Lancet Infect Dis 11(9), 2011
PMID: 21703928

Public health hazards in Poland posed by foodstuffs contaminated with E. coli O104:H4 bacterium from the recent European outbreak.
Bilinski P, Kapka-Skrzypczak L, Posobkiewicz M, Bondaryk M, Holownia P, Wojtyla A., Ann Agric Environ Med 19(1), 2012
PMID: 22462438

Escherichia coli O104:H4 outbreak--have we learnt a lesson from it?
Bloch SK, Felczykowska A, Nejman-Falenczyk B., Acta Biochim. Pol. 59(4), 2012
PMID: 23240107

E. coli O104:H4 outbreak and haemolytic-uraemic syndrome.
Borgatta B, Kmet-Lunacek N, Rello J., Med Intensiva 36(8), 2012
PMID: 22244215

Clinical features of critically ill patients with Shiga toxin-induced hemolytic uremic syndrome.
Braune SA, Wichmann D, von Heinz MC, Nierhaus A, Becker H, Meyer TN, Meyer GP, Muller-Schulz M, Fricke J, de Weerth A, Hoepker WW, Fiehler J, Magnus T, Gerloff C, Panzer U, Stahl RA, Wegscheider K, Kluge S., Crit. Care Med. 41(7), 2013
PMID: 23660733

Genome sequence analyses of two isolates from the recent Escherichia coli outbreak in Germany reveal the emergence of a new pathotype: Entero-Aggregative-Haemorrhagic Escherichia coli (EAHEC).
Brzuszkiewicz E, Thurmer A, Schuldes J, Leimbach A, Liesegang H, Meyer FD, Boelter J, Petersen H, Gottschalk G, Daniel R., Arch. Microbiol. 193(12), 2011
PMID: 21713444

German outbreak of Escherichia coli O104:H4 associated with sprouts.
Buchholz U, Bernard H, Werber D, Bohmer MM, Remschmidt C, Wilking H, Delere Y, an der Heiden M, Adlhoch C, Dreesman J, Ehlers J, Ethelberg S, Faber M, Frank C, Fricke G, Greiner M, Hohle M, Ivarsson S, Jark U, Kirchner M, Koch J, Krause G, Luber P, Rosner B, Stark K, Kuhne M., N. Engl. J. Med. 365(19), 2011
PMID: 22029753

Enteroaggregative E. coli O104 from an outbreak of HUS in Germany 2011, could it happen again?
Chattaway MA, Dallman T, Okeke IN, Wain J., J Infect Dev Ctries 5(6), 2011
PMID: 21727640

2011 German Escherichia coli O104:H4 outbreak: whole-genome phylogeny without alignment.
Cheung MK, Li L, Nong W, Kwan HS., BMC Res Notes 4(), 2011
PMID: 22166159

Rapid MALDI-TOF mass spectrometry strain typing during a large outbreak of Shiga-Toxigenic Escherichia coli.
Christner M, Trusch M, Rohde H, Kwiatkowski M, Schluter H, Wolters M, Aepfelbacher M, Hentschke M., PLoS ONE 9(7), 2014
PMID: 25003758

Colonic ischaemia as a severe Shiga toxin/verotoxin producing Escherichia coli O104:H4 complication in a patient without haemolytic uraemic syndrome, Germany, June 2011.
Cordesmeyer S, Peitz U, Godde N, Kasper HU, Hoffmann MW, Allemeyer E., Euro Surveill. 16(25), 2011
PMID: 21722614

Therapeutic concentrations of antibiotics inhibit Shiga toxin release from enterohemorrhagic E. coli O104:H4 from the 2011 German outbreak.
Corogeanu D, Willmes R, Wolke M, Plum G, Utermohlen O, Kronke M., BMC Microbiol. 12(), 2012
PMID: 22853739

Increased expression of complement regulators CD55 and CD59 on peripheral blood cells in patients with EAHEC O104:H4 infection.
Dammermann W, Schipper P, Ullrich S, Fraedrich K, Schulze Zur Wiesch J, Frundt T, Tiegs G, Lohse A, Luth S., PLoS ONE 8(9), 2013
PMID: 24086391

Specific detection of enteroaggregative hemorrhagic Escherichia coli O104:H4 strains by use of the CRISPR locus as a target for a diagnostic real-time PCR.
Delannoy S, Beutin L, Burgos Y, Fach P., J. Clin. Microbiol. 50(11), 2012
PMID: 22895033

The 2011 Shiga toxin-producing Escherichia coli O104:H4 German outbreak: a lesson in genomic plasticity.
Denamur E., Clin. Microbiol. Infect. 17(8), 2011
PMID: 21781204

Transmission of shiga toxin-producing Escherichia coli O104:H4 at a family party possibly due to contamination by a food handler, Germany 2011.
Diercke M, Kirchner M, Claussen K, Mayr E, Strotmann I, Frangenberg J, Schiffmann A, Bettge-Weller G, Arvand M, Uphoff H., Epidemiol. Infect. 142(1), 2013
PMID: 23561267

Multidisciplinary response to the Escherichia coli 0104 outbreak in Europe.
Dodd CC, Cooper MJ., Mil Med 177(11), 2012
PMID: 23198523

Soluble plasma VE-cadherin concentrations are elevated in patients with STEC infection and haemolytic uraemic syndrome: a case-control study.
Doulgere J, Otto B, Nassour M, Wolters-Eisfeld G, Rohde H, Magnus T, Wagener C, Streichert T., BMJ Open 5(3), 2015
PMID: 25757942

[Clinical symptoms, treatment and outcome of EHEC and EHEC-HUS patients treated as in-patients].
Ducker C, Dautel P, Wagner K, Przewozna J, Oehlerking S, Repenthin J, Bruning R, Meyer TN, Faiss S., Dtsch. Med. Wochenschr. 136(36), 2011
PMID: 21882131

[Epidemics and pandemics in general practice. What can we learn from the swine flu (H1N1) and EHEC outbreak?].
Eisele M, Hansen H, Wagner HO, von Leitner E, Pohontsch N, Scherer M., Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 57(6), 2014
PMID: 24817143

Using an outbreak to study the sensitivity of the surveillance of enterohaemorrhagic Escherichia coli and other enteropathic Escherichia coli in Bavaria, Germany, January to October 2011.
Englund H, Hautmann W., Euro Surveill. 17(34), 2012
PMID: 22939211

Consensus report: E. coli O104:H4 (HUSEC041) and the potential threat to European water supplies.
Exner M, Hartemann P, Hunter PR, Levi Y, Loret JF, Mathys W, Villesot D, Wilhelm M., Int J Hyg Environ Health 214(6), 2011
PMID: 22206100

Large and ongoing outbreak of haemolytic uraemic syndrome, Germany, May 2011.
Frank C, Faber MS, Askar M, Bernard H, Fruth A, Gilsdorf A, Hohle M, Karch H, Krause G, Prager R, Spode A, Stark K, Werber D; HUS investigation team, Atzpodien K, Behnke S, Bohmer M, Buchholz U, Dehnert M, Hermes J, Krugermann K, Marx M, Mucke I, Nachtnebel M, Neifer J, Nielsen S, Noll I, Prahm K, Preuss U, Remschmidt C, Rieck T, Rosner B, Schink S, Schmidt D, Schwarz F, Schweickert B, Stocker P, Suss T, Ultsch B, Wadl M, Fell G, Dreesmann J, Panzer U, Harendza S, Oh J, Sudmann S, Juers U., Euro Surveill. 16(21), 2011
PMID: 21632020

Results of surveillance for infections with Shiga toxin-producing Escherichia coli (STEC) of serotype O104:H4 after the large outbreak in Germany, July to December 2011.
Frank C, Milde-Busch A, Werber D., Euro Surveill. 19(14), 2014
PMID: 24739983

Epidemic profile of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in Germany.
Frank C, Werber D, Cramer JP, Askar M, Faber M, an der Heiden M, Bernard H, Fruth A, Prager R, Spode A, Wadl M, Zoufaly A, Jordan S, Kemper MJ, Follin P, Muller L, King LA, Rosner B, Buchholz U, Stark K, Krause G; HUS Investigation Team, Abu Sin M, Adlhoch C, Alpers K, Altmann D, Altmann M, Arends K, Atzpodien K, Behnke S, Benzler J, Bergholz A, Bielecke J, Bohmer M, Brodhun B, Burger R, Cai W, Claus H, Christner M, Cyberski C, Dehnert M, Delere Y, Dudareva S, Eckmanns T, Espelage W, Falkenhorst G, Fiebig L, Fraedrich K, Gilsdorf A, Greutelaers B, Gunsenheimer-Bartmeyer B, Haar K, Haas W, Hamouda O, Hauer B, Hellenbrand W, Hermes J, Hohle M, Koch J, Kopke K, Krugermann K, Laude G, Lee MH, Liss I, Lohse AW, Luchtenberg M, Marx M, Meyer D, Mielke M, Milde-Busch A, Mucke I, Nachtnebel M, Neifer J, Nielsen S, Noll I, Offergeld R, Oh J, Pfeiffer Y, Pohland R, Prahm K, Preuss U, Reiter S, Remschmidt C, Reuss A, Rexroth U, Richter M, Rieck T, Rohde H, Sailer A, Santos-Hovener C, Schaade L, Schink S, Schmiedel S, Schmidt D, Schoene C, Schoneberg I, Schuster M, Schwarz F, Schweickert B, Stocker P, Su T, Takla A, Tietze E, Ultsch B, Ung M, Kang Z, Velasco E, Walter D, Weiss B, Wilking H, Zimmermann R, Zhang W, Zunk J., N. Engl. J. Med. 365(19), 2011
PMID: 21696328

Microparticle generation and leucocyte death in Shiga toxin-mediated HUS.
Ge S, Hertel B, Emden SH, Beneke J, Menne J, Haller H, von Vietinghoff S., Nephrol. Dial. Transplant. 27(7), 2012
PMID: 22234918

Ciprofloxacin reduces the risk of hemolytic uremic syndrome in patients with Escherichia coli O104:H4-associated diarrhea.
Geerdes-Fenge HF, Lobermann M, Nurnberg M, Fritzsche C, Koball S, Henschel J, Hohn R, Schober HC, Mitzner S, Podbielski A, Reisinger EC., Infection 41(3), 2013
PMID: 23292662

Rapid and sensitive detection of Shiga toxin-producing Escherichia coli directly from stool samples by real-time PCR in comparison to culture, enzyme immunoassay and Vero cell cytotoxicity assay.
Gerritzen A, Wittke JW, Wolff D., Clin. Lab. 57(11-12), 2011
PMID: 22239032

Comparative genomics of recent Shiga toxin-producing Escherichia coli O104:H4: short-term evolution of an emerging pathogen.
Grad YH, Godfrey P, Cerquiera GC, Mariani-Kurkdjian P, Gouali M, Bingen E, Shea TP, Haas BJ, Griggs A, Young S, Zeng Q, Lipsitch M, Waldor MK, Weill FX, Wortman JR, Hanage WP., MBio 4(1), 2013
PMID: 23341549

Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011.
Grad YH, Lipsitch M, Feldgarden M, Arachchi HM, Cerqueira GC, Fitzgerald M, Godfrey P, Haas BJ, Murphy CI, Russ C, Sykes S, Walker BJ, Wortman JR, Young S, Zeng Q, Abouelleil A, Bochicchio J, Chauvin S, Desmet T, Gujja S, McCowan C, Montmayeur A, Steelman S, Frimodt-Moller J, Petersen AM, Struve C, Krogfelt KA, Bingen E, Weill FX, Lander ES, Nusbaum C, Birren BW, Hung DT, Hanage WP., Proc. Natl. Acad. Sci. U.S.A. 109(8), 2012
PMID: 22315421

Treatment of severe neurological deficits with IgG depletion through immunoadsorption in patients with Escherichia coli O104:H4-associated haemolytic uraemic syndrome: a prospective trial.
Greinacher A, Friesecke S, Abel P, Dressel A, Stracke S, Fiene M, Ernst F, Selleng K, Weissenborn K, Schmidt BM, Schiffer M, Felix SB, Lerch MM, Kielstein JT, Mayerle J., Lancet 378(9797), 2011
PMID: 21890192

[Hospital surveillance during major outbreaks of community-acquired diseases. Pandemic Influenza Hospital Surveillance (PIKS) 2009/2010 and Surveillance of Bloody Diarrhea (SBD) 2011].
Greutelaers B, Wadl M, Nachtnebel M, Rieck T, Hogan B, Adlhoch C, Eckmanns T, Benzler J., Dtsch. Med. Wochenschr. 138(13), 2013
PMID: 23512362

Upregulation of Shiga toxin receptor CD77/Gb3 and interleukin-1β expression in the brain of EHEC patients with hemolytic uremic syndrome and neurologic symptoms.
Hagel C, Krasemann S, Loffler J, Puschel K, Magnus T, Glatzel M., Brain Pathol. 25(2), 2014
PMID: 24989888

Secondary transmissions during the outbreak of Shiga toxin-producing Escherichia coli O104 in Hesse, Germany, 2011.
Hauri A, Gotsch U, Strotmann I, Krahn J, Bettge-Weller G, Westbrock H, Bellinger O, Uphoff H., Euro Surveill. 16(31), 2011
PMID: 21871215

Lessons Learned From Outbreaks of Shiga Toxin Producing Escherichia coli.
Hauswaldt S, Nitschke M, Sayk F, Solbach W, Knobloch JK., Curr Infect Dis Rep 15(1), 2013
PMID: 23212721

[On the risk of spread of E. coli/EHEC O104:H4 stx 2 positive bacteria via sewerage treatment plants during the 2011 EHEC outbreak in north Germany].
Heinemeyer EA, Luden K, Monazahian M., Gesundheitswesen 75(8-9), 2012
PMID: 23172599

Rapid identification and validation of specific molecular targets for detection of Escherichia coli O104:H4 outbreak strain by use of high-throughput sequencing data from nine genomes.
Ho CC, Yuen KY, Lau SK, Woo PC., J. Clin. Microbiol. 49(10), 2011
PMID: 21880963

Bayesian nowcasting during the STEC O104:H4 outbreak in Germany, 2011.
Hohle M, an der Heiden M., Biometrics 70(4), 2014
PMID: 24930473

[A notice from epidemiological investigation of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in Germany, 2011].
Huang X, Lu LL, Deng XL, Huang Q, Liang JH, Zhang YH, Yang XF., Zhonghua Liu Xing Bing Xue Za Zhi 33(1), 2012
PMID: 22575123

Advances in pathogenesis and therapy of hemolytic uremic syndrome caused by Shiga toxin-2.
Ibarra C, Amaral MM, Palermo MS., IUBMB Life 65(10), 2013
PMID: 24014500

Highlights from the clinical symposium on Shiga toxin-producing Escherichia coli/ haemolytic uremic syndrome, Berlin, September 2011
Jansen A., 2011

Molecular epidemiology of a household outbreak of Shiga-toxin-producing Escherichia coli in Poland due to secondary transmission of STEC O104:H4 from Germany.
Januszkiewicz A, Szych J, Rastawicki W, Wolkowicz T, Chrost A, Leszczynska B, Kuzma E, Roszkowska-Blaim M, Gierczynski R., J. Med. Microbiol. 61(Pt 4), 2011
PMID: 22135021

Evaluation of shiga toxin-producing Escherichia coli (STEC) method for the detection and identification of STEC O104 strains from sprouts
Jinneman KC, Waite-Cusic JG, Yoshitomi KJ., Food Microbiol. 30(1), 2012
PMID: IND44689868

Overview and Historical Perspectives.
Kaper JB, O'Brien AD., Microbiol Spectr 2(6), 2014
PMID: 25590020

The enemy within us: lessons from the 2011 European Escherichia coli O104:H4 outbreak.
Karch H, Denamur E, Dobrindt U, Finlay BB, Hengge R, Johannes L, Ron EZ, Tonjum T, Sansonetti PJ, Vicente M., EMBO Mol Med 4(9), 2012
PMID: 22927122

[Management of patients with EHEC/HUS. Lessons and perspectives from clinical infectious disease specialists].
Kern WV., Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56(1), 2013
PMID: 23275960

Best supportive care and therapeutic plasma exchange with or without eculizumab in Shiga-toxin-producing E. coli O104:H4 induced haemolytic-uraemic syndrome: an analysis of the German STEC-HUS registry.
Kielstein JT, Beutel G, Fleig S, Steinhoff J, Meyer TN, Hafer C, Kuhlmann U, Bramstedt J, Panzer U, Vischedyk M, Busch V, Ries W, Mitzner S, Mees S, Stracke S, Nurnberger J, Gerke P, Wiesner M, Sucke B, Abu-Tair M, Kribben A, Klause N, Schindler R, Merkel F, Schnatter S, Dorresteijn EM, Samuelsson O, Brunkhorst R; Collaborators of the DGfN STEC-HUS registry., Nephrol. Dial. Transplant. 27(10), 2012
PMID: 23114903

Psychiatric symptoms in patients with Shiga toxin-producing E. coli O104:H4 induced haemolytic-uraemic syndrome.
Kleimann A, Toto S, Eberlein CK, Kielstein JT, Bleich S, Frieling H, Sieberer M., PLoS ONE 9(7), 2014
PMID: 25007072

Antibiotic therapy in Shiga toxin producing Escherichia coli infection and colonization
Knobloch JK, Hauswaldt S, Solbach W, Nitschke M, Sayk F., 2013

Household transmission of haemolytic uraemic syndrome associated with Escherichia coli O104:H4 in the Netherlands, May 2011.
Kuijper EJ, Soonawala D, Vermont C, van Dissel JT., Euro Surveill. 16(25), 2011
PMID: 21722613

A comparison of Shiga-toxin 2 bacteriophage from classical enterohemorrhagic Escherichia coli serotypes and the German E. coli O104:H4 outbreak strain.
Laing CR, Zhang Y, Gilmour MW, Allen V, Johnson R, Thomas JE, Gannon VP., PLoS ONE 7(5), 2012
PMID: 22649523

[Structures and concepts for nationwide outbreak management in a federal state].
Leidel J, Feil F., Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56(1), 2013
PMID: 23275961

[EHEC-associated colon stenosis after ulcerous-chronic haemorrhagic colitis and consecutive resulting ileus].
Lipp MJ, Schirmer J, Feyerabend B, Stavrou GA, Cordruwisch W, Faiss S, Oldhafer KJ., Z Gastroenterol 50(5), 2012
PMID: 22581700

Cerebral magnetic resonance imaging findings in adults with haemolytic uraemic syndrome following an infection with Escherichia coli, subtype O104:H4.
Lobel U, Eckert B, Simova O, Meier-Cillien M, Kluge S, Gerloff C, Rother J, Magnus T, Fiehler J., Clin Neuroradiol 24(2), 2013
PMID: 23811994

Psychological outcome, fatigue, and quality of life after infection with shiga toxin-producing Escherichia coli O104.
Lowe B, Andresen V, Fraedrich K, Gappmayer K, Wegscheider K, Treszl A, Riegel B, Rose M, Lohse AW, Broicher W., Clin. Gastroenterol. Hepatol. 12(11), 2014
PMID: 24632347

[Risk communication of the Federal Institute for Risk Assessment during a food-related outbreak].
Lohmann M, Epp A, Roder B, Bol GF., Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56(1), 2013
PMID: 23275962

[Risk communication of the Federal Institute for Risk Assessment during a food-related outbreak].
Lohmann M, Epp A, Roder B, Bol GF., Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56(1), 2013
PMID: 23275962

A culture-independent sequence-based metagenomics approach to the investigation of an outbreak of Shiga-toxigenic Escherichia coli O104:H4.
Loman NJ, Constantinidou C, Christner M, Rohde H, Chan JZ, Quick J, Weir JC, Quince C, Smith GP, Betley JR, Aepfelbacher M, Pallen MJ., JAMA 309(14), 2013
PMID: 23571589

An outbreak of Shiga toxin-producing Escherichia coli O104:H4 hemolytic uremic syndrome in Germany: presentation and short-term outcome in children.
Loos S, Ahlenstiel T, Kranz B, Staude H, Pape L, Hartel C, Vester U, Buchtala L, Benz K, Hoppe B, Beringer O, Krause M, Muller D, Pohl M, Lemke J, Hillebrand G, Kreuzer M, Konig J, Wigger M, Konrad M, Haffner D, Oh J, Kemper MJ., Clin. Infect. Dis. 55(6), 2012
PMID: 22670043

Circulating microRNAs in patients with Shiga-Toxin-producing E. coli O104:H4 induced hemolytic uremic syndrome.
Lorenzen JM, Menne J, Schmidt BM, Schmidt M, Martino F, Dietrich R, Samiri S, Worthmann H, Heeren M, Weissenborn K, Haller H, Schiffer M, Kielstein JT, Thum T., PLoS ONE 7(10), 2012
PMID: 23071762

Serum neutrophil gelatinase-associated lipocalin (NGAL) in patients with Shiga toxin mediated haemolytic uraemic syndrome (STEC-HUS).
Lukasz A, Beneke J, Menne J, Vetter F, Schmidt BM, Schiffer M, Haller H, Kumpers P, Kielstein JT., Thromb. Haemost. 111(2), 2013
PMID: 24172823

Applicability of DiversiLab repetitive sequence-based PCR method in epidemiological typing of enterohemorrhagic Escherichia coli (EHEC).
Lukinmaa-Aberg S, Horsma J, Pasanen T, Mero S, Aulu L, Vaara M, Siitonen A, Antikainen J., Foodborne Pathog. Dis. 10(7), 2013
PMID: 23692078

Prevention of hemolytic uremic syndrome with daily bowel lavage in patients with Shiga toxin-producing enterohemorrhagic Escherichia coli O104:H4 infection.
Luth S, Frundt TW, Rosch T, Schlee C, Lohse AW., JAMA Intern Med 174(6), 2014
PMID: 24781800

The neurological syndrome in adults during the 2011 northern German E. coli serotype O104:H4 outbreak.
Magnus T, Rother J, Simova O, Meier-Cillien M, Repenthin J, Moller F, Gbadamosi J, Panzer U, Wengenroth M, Hagel C, Kluge S, Stahl RK, Wegscheider K, Urban P, Eckert B, Glatzel M, Fiehler J, Gerloff C., Brain 135(Pt 6), 2012
PMID: 22539260

Origin Detection During Food-borne Disease Outbreaks - A Case Study of the 2011 EHEC/HUS Outbreak in Germany.
Manitz J, Kneib T, Schlather M, Helbing D, Brockmann D., PLoS Curr 6(), 2014
PMID: 24818065

An imported case of bloody diarrhea in the Czech Republic caused by a hybrid enteroaggregative hemorrhagic Escherichia coli (EAHEC) O104:H4 strain associated with the large outbreak in Germany, May 2011.
Marejkova M, Rohacova H, Reisingerova M, Petras P., Folia Microbiol. (Praha) 57(2), 2012
PMID: 22258751

A simple shortcut to unsupervised alignment-free phylogenetic genome groupings, even from unassembled sequencing reads.
Maurer-Stroh S, Gunalan V, Wong WC, Eisenhaber F., J Bioinform Comput Biol 11(6), 2013
PMID: 24372034

Prospective genomic characterization of the German enterohemorrhagic Escherichia coli O104:H4 outbreak by rapid next generation sequencing technology.
Mellmann A, Harmsen D, Cummings CA, Zentz EB, Leopold SR, Rico A, Prior K, Szczepanowski R, Ji Y, Zhang W, McLaughlin SF, Henkhaus JK, Leopold B, Bielaszewska M, Prager R, Brzoska PM, Moore RL, Guenther S, Rothberg JM, Karch H., PLoS ONE 6(7), 2011
PMID: 21799941

[Treatment of typical hemolytic-uremic syndrome. Knowledge gained from analyses of the 2011 E. coli outbreak].
Menne J, Kielstein JT, Wenzel U, Stahl RA., Internist (Berl) 53(12), 2012
PMID: 23179596

Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study.
Menne J, Nitschke M, Stingele R, Abu-Tair M, Beneke J, Bramstedt J, Bremer JP, Brunkhorst R, Busch V, Dengler R, Deuschl G, Fellermann K, Fickenscher H, Gerigk C, Goettsche A, Greeve J, Hafer C, Hagenmuller F, Haller H, Herget-Rosenthal S, Hertenstein B, Hofmann C, Lang M, Kielstein JT, Klostermeier UC, Knobloch J, Kuehbacher M, Kunzendorf U, Lehnert H, Manns MP, Menne TF, Meyer TN, Michael C, Munte T, Neumann-Grutzeck C, Nuernberger J, Pavenstaedt H, Ramazan L, Renders L, Repenthin J, Ries W, Rohr A, Rump LC, Samuelsson O, Sayk F, Schmidt BM, Schnatter S, Schocklmann H, Schreiber S, von Seydewitz CU, Steinhoff J, Stracke S, Suerbaum S, van de Loo A, Vischedyk M, Weissenborn K, Wellhoner P, Wiesner M, Zeissig S, Buning J, Schiffer M, Kuehbacher T; EHEC-HUS consortium, Bergmann M, Berhorst-Ziadi K, Diedrich R, Emden SH, Hampel A, Muller A, Richters N, Samiri S, Sartison A, Vetter F, Bange FC, Bahte SK, Bintaro P, Fleig S, Gwinner W, Hanke N, Heeren M, Hiss M, Linnenweber-Held S, Lukasz AH, Merkel S, Reising A, Schmitt R, Schwarz A, von Vietinghoff S, Wagner A, Worthmann H, Kaminski S, Emden SH, Arlt A, Bethge J, Bewig B, Guenther R, Hellriegel H, Kristen H, Moller B, Ott SJ, Schubert S, Seeger M, Aden K, Derad I, Duderstadt S, Fullgraf H, Haas C, Jankowiak C, Kodal A, Ketel JC, Kurowski V, Lehne W, Meier M, Meinhardt C, Muck P, Sauer A, Schmidt K, Solbach W, Sufke S, Weitz G, Werth S, Wolfrum S, Zullich H, Valentin R, Kuhlmann U, Eschweiler K, Kucukkoylu S, Klempin J, Kreft B, Kucharzik T, Fussek S, Kroencke KW., BMJ 345(), 2012
PMID: 22815429

Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli O104:H4 strain from the 2011 outbreak in Germany.
Merabishvili M, De Vos D, Verbeken G, Kropinski AM, Vandenheuvel D, Lavigne R, Wattiau P, Mast J, Ragimbeau C, Mossong J, Scheres J, Chanishvili N, Vaneechoutte M, Pirnay JP., PLoS ONE 7(12), 2012
PMID: 23285164

Presence of enterohemorrhagic Escherichia coli ST678/O104:H4 in France prior to 2011.
Monecke S, Mariani-Kurkdjian P, Bingen E, Weill FX, Baliere C, Slickers P, Ehricht R., Appl. Environ. Microbiol. 77(24), 2011
PMID: 22003010

Characteristics of the Shiga-toxin-producing enteroaggregative Escherichia coli O104:H4 German outbreak strain and of STEC strains isolated in Spain.
Mora A, Herrrera A, Lopez C, Dahbi G, Mamani R, Pita JM, Alonso MP, Llovo J, Bernardez MI, Blanco JE, Blanco M, Blanco J., Int. Microbiol. 14(3), 2011
PMID: 22101411

Escherichia coli: great diversity around a common core.
Moriel DG, Rosini R, Seib KL, Serino L, Pizza M, Rappuoli R., MBio 3(3), 2012
PMID: 22669628

Bloody diarrhea caused by enterohemorrhagic Escherichia coli (EHEC).
Neumann H, Hunstiger M, Langner C, Neurath MF, Vieth M., Endoscopy 43 Suppl 2 UCTN(), 2011
PMID: 21660908

Association between azithromycin therapy and duration of bacterial shedding among patients with Shiga toxin-producing enteroaggregative Escherichia coli O104:H4.
Nitschke M, Sayk F, Hartel C, Roseland RT, Hauswaldt S, Steinhoff J, Fellermann K, Derad I, Wellhoner P, Buning J, Tiemer B, Katalinic A, Rupp J, Lehnert H, Solbach W, Knobloch JK., JAMA 307(10), 2012
PMID: 22416100

Enterohemorrhagic Escherichia coli Infections and the Hemolytic-Uremic Syndrome.
Page AV, Liles WC., Med. Clin. North Am. 97(4), 2013
PMID: 23809720

BG7: a new approach for bacterial genome annotation designed for next generation sequencing data.
Pareja-Tobes P, Manrique M, Pareja-Tobes E, Pareja E, Tobes R., PLoS ONE 7(11), 2012
PMID: 23185310

New insights into Shiga toxin-mediated endothelial dysfunction in hemolytic uremic syndrome.
Petruzziello-Pellegrini TN, Moslemi-Naeini M, Marsden PA., Virulence 4(6), 2013
PMID: 23955166

O157:H7 and O104:H4 Vero/Shiga toxin-producing Escherichia coli outbreaks: respective role of cattle and humans.
Pierard D, De Greve H, Haesebrouck F, Mainil J., Vet. Res. 43(), 2012
PMID: 22330148

Alignment-free design of highly discriminatory diagnostic primer sets for Escherichia coli O104:H4 outbreak strains.
Pritchard L, Holden NJ, Bielaszewska M, Karch H, Toth IK., PLoS ONE 7(4), 2012
PMID: 22496820

Identification of the Shiga toxin-producing Escherichia coli O104:H4 strain responsible for a food poisoning outbreak in Germany by PCR.
Qin J, Cui Y, Zhao X, Rohde H, Liang T, Wolters M, Li D, Belmar Campos C, Christner M, Song Y, Yang R., J. Clin. Microbiol. 49(9), 2011
PMID: 21752971

Escherichia coli O104:H4 outbreak in Germany--clarification of the origin of the epidemic.
Radosavljevic V, Finke EJ, Belojevic G., Eur J Public Health 25(1), 2014
PMID: 24736168

Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany.
Rasko DA, Webster DR, Sahl JW, Bashir A, Boisen N, Scheutz F, Paxinos EE, Sebra R, Chin CS, Iliopoulos D, Klammer A, Peluso P, Lee L, Kislyuk AO, Bullard J, Kasarskis A, Wang S, Eid J, Rank D, Redman JC, Steyert SR, Frimodt-Moller J, Struve C, Petersen AM, Krogfelt KA, Nataro JP, Schadt EE, Waldor MK., N. Engl. J. Med. 365(8), 2011
PMID: 21793740

Comparative study on the high pressure inactivation behavior of the Shiga toxin-producing Escherichia coli O104:H4 and O157:H7 outbreak strains and a non-pathogenic surrogate.
Reineke K, Sevenich R, Hertwig C, Janßen T, Frohling A, Knorr D, Wieler LH, Schluter O., Food Microbiol. 46(), 2014
PMID: 25475283

Cyclic-di-GMP signalling and biofilm-related properties of the Shiga toxin-producing 2011 German outbreak Escherichia coli O104:H4.
Richter AM, Povolotsky TL, Wieler LH, Hengge R., EMBO Mol Med 6(12), 2014
PMID: 25361688

Quality of life one year post-Shiga toxin-producing Escherichia coli O104 infection--a prospective cohort study.
Riegel B, Broicher W, Wegscheider K, Andresen V, Brahler E, Lohse AW, Lowe B., Neurogastroenterol. Motil. 27(3), 2015
PMID: 25581112

[The EHEC O104:H4 outbreak in Germany 2011 - lessons learned?!].
Rissland J, Kielstein JT, Stark K, Wichmann-Schauer H, Stumpel F, Pulz M., Gesundheitswesen 75(4), 2013
PMID: 23576144

Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4.
Rohde H, Qin J, Cui Y, Li D, Loman NJ, Hentschke M, Chen W, Pu F, Peng Y, Li J, Xi F, Li S, Li Y, Zhang Z, Yang X, Zhao M, Wang P, Guan Y, Cen Z, Zhao X, Christner M, Kobbe R, Loos S, Oh J, Yang L, Danchin A, Gao GF, Song Y, Li Y, Yang H, Wang J, Xu J, Pallen MJ, Wang J, Aepfelbacher M, Yang R; E. coli O104:H4 Genome Analysis Crowd-Sourcing Consortium, Holt KE, Studholme DJ, Feldgarden M, Manrique M., N. Engl. J. Med. 365(8), 2011
PMID: 21793736

[Managing EHEC in hospital routine].
Ross B, Witzke O, Kribben A, Heintschel von Heinegg E, Buer J, Gerken G, Fiedler M, Popp W., Dtsch. Med. Wochenschr. 137(18), 2012
PMID: 22531941

Antagonistic effects of probiotic Escherichia coli Nissle 1917 on EHEC strains of serotype O104:H4 and O157:H7.
Rund SA, Rohde H, Sonnenborn U, Oelschlaeger TA., Int. J. Med. Microbiol. 303(1), 2013
PMID: 23312798

[The HUS epidemic in the summer of 2011 was severe. German and Swedish experiences of the EHEC outbreak].
Samuelsson O, Follin P, Rundgren M, Rylander C, Selga D, Stahl A., Lakartidningen 109(25), 2012
PMID: 22838113

Epidemiological analysis of a cluster within the outbreak of Shiga toxin-producing Escherichia coli serotype O104:H4 in Northern Germany, 2011.
Scharlach M, Diercke M, Dreesman J, Jahn N, Krieck M, Beyrer K, Claußen K, Pulz M, Floride R., Int J Hyg Environ Health 216(3), 2012
PMID: 23154087

[Segmental necrotizing colitis in a patient with E. coli O104:H4 infection].
Scheppach W, Reissmann N, Breunig E, Konwisorz A, Schwarz TF, Muller JG, Tappe D., Z Gastroenterol 50(2), 2012
PMID: 22298100

Characteristics of the enteroaggregative Shiga toxin/verotoxin-producing Escherichia coli O104:H4 strain causing the outbreak of haemolytic uraemic syndrome in Germany, May to June 2011.
Scheutz F, Nielsen EM, Frimodt-Moller J, Boisen N, Morabito S, Tozzoli R, Nataro JP, Caprioli A., Euro Surveill. 16(24), 2011
PMID: 21699770

Genome sequence of E. coli O104:H4 leads to rapid development of a targeted antimicrobial agent against this emerging pathogen.
Scholl D, Gebhart D, Williams SR, Bates A, Mandrell R., PLoS ONE 7(3), 2012
PMID: 22432037

TV news and concerns about - the EHEC-outbreak 2011 in Germany.
Schulz C, Schutte K, Jacobi CA, Hulsemann JL, Malfertheiner P., Z Gastroenterol 52(3), 2014
PMID: 24622869

Neuropsychological outcome after complicated Shiga toxin-producing Escherichia coli infection.
Simova O, Weineck G, Schuetze T, Wegscheider K, Panzer U, Stahl RA, Gerloff C, Magnus T., PLoS ONE 9(7), 2014
PMID: 25050708

Carrier prevalence, secondary household transmission, and long-term shedding in 2 districts during the Escherichia coli O104:H4 outbreak in Germany, 2011.
Sin MA, Takla A, Flieger A, Prager R, Fruth A, Tietze E, Fink E, Korte J, Schink S, Hohle M, Eckmanns T., J. Infect. Dis. 207(3), 2012
PMID: 23175763

[Patient with haemolytic uremic syndrome and Escherichia coli (EHEC) infection].
Soolsma J, Yo M, Bakker L, Kingma P, Gamadia L, Lobatto S., Ned Tijdschr Geneeskd 155(35), 2011
PMID: 21902851

Escherichia coli O104:H4 outbreak from sprouted seeds.
Soon JM, Seaman P, Baines RN., Int J Hyg Environ Health 216(3), 2012
PMID: 22898546

Renal and neurological involvement in typical Shiga toxin-associated HUS.
Trachtman H, Austin C, Lewinski M, Stahl RA., Nat Rev Nephrol 8(11), 2012
PMID: 22986362

A rapid procedure for the detection and isolation of enterohaemorrhagic Escherichia coli (EHEC) serogroup O26, O103, O111, O118, O121, O145 and O157 strains and the aggregative EHEC O104:H4 strain from ready-to-eat vegetables.
Tzschoppe M, Martin A, Beutin L., Int. J. Food Microbiol. 152(1-2), 2011
PMID: 22071287

Symptoms and clinical course of EHEC O104 infection in hospitalized patients: a prospective single center study.
Ullrich S, Bremer P, Neumann-Grutzeck C, Otto H, Ruther C, von Seydewitz CU, Meyer GP, Ahmadi-Simab K, Rother J, Hogan B, Schwenk W, Fischbach R, Caselitz J, Puttfarcken J, Huggett S, Tiedeken P, Pober J, Kirkiles-Smith NC, Hagenmuller F., PLoS ONE 8(2), 2013
PMID: 23460784

Should health organizations use web 2.0 media in times of an infectious disease crisis? An in-depth qualitative study of citizens' information behavior during an EHEC outbreak.
van Velsen L, van Gemert-Pijnen JE, Beaujean DJ, Wentzel J, van Steenbergen JE., J. Med. Internet Res. 14(6), 2012
PMID: 23257066

Analyzing consumers' reactions to news coverage of the 2011 Escherichia coli O104:H4 outbreak, using the Extended Parallel Processing Model.
De Vocht M, Cauberghe V, Sas B, Uyttendaele M., J. Food Prot. 76(3), 2013
PMID: 23462085

Duration of fecal shedding of Shiga toxin-producing Escherichia coli O104:H4 in patients infected during the 2011 outbreak in Germany: a multicenter study.
Vonberg RP, Hohle M, Aepfelbacher M, Bange FC, Belmar Campos C, Claussen K, Christner M, Cramer JP, Haller H, Hornef M, Fickenscher H, Fraedrich K, Knobloch JK, Kuhbacher T, Manns MP, Nitschke M, Peters G, Pulz M, Rohde H, Roseland RT, Sayk F, Schaumburg F, Schocklmann HO, Schubert S, Solbach W, Karch H, Suerbaum S., Clin. Infect. Dis. 56(8), 2013
PMID: 23300241

Enhanced surveillance during a large outbreak of bloody diarrhoea and haemolytic uraemic syndrome caused by Shiga toxin/verotoxin-producing Escherichia coli in Germany, May to June 2011.
Wadl M, Rieck T, Nachtnebel M, Greutelaers B, an der Heiden M, Altmann D, Hellenbrand W, Faber M, Frank C, Schweickert B, Krause G, Benzler J, Eckmanns T; HUS surveillance and laboratory team, Sin MA, Behnke S, Brodhun B, Claus H, Delere Y, Fiebig L, Bartmeyer BG, Gilsdorf A, Haar K, Hauer B, Ung M, Kang Z, Luchtenberg M, Mucke I, Neifer J, Noll I, Schink S, Schoneberg I, Velasco E, Weib B., Euro Surveill. 16(24), 2011
PMID: 21699769

Trace-back and trace-forward tools developed ad hoc and used during the STEC O104:H4 outbreak 2011 in Germany and generic concepts for future outbreak situations.
Weiser AA, Gross S, Schielke A, Wigger JF, Ernert A, Adolphs J, Fetsch A, Muller-Graf C, Kasbohrer A, Mosbach-Schulz O, Appel B, Greiner M., Foodborne Pathog. Dis. 10(3), 2012
PMID: 23268760

Neurologic manifestations of E coli infection-induced hemolytic-uremic syndrome in adults.
Weissenborn K, Donnerstag F, Kielstein JT, Heeren M, Worthmann H, Hecker H, Schmitt R, Schiffer M, Pasedag T, Schuppner R, Tryc AB, Raab P, Hartmann H, Ding XQ, Hafer C, Menne J, Schmidt BM, Bultmann E, Haller H, Dengler R, Lanfermann H, Giesemann AM., Neurology 79(14), 2012
PMID: 22993286

Central nervous system involvement in adults with epidemic hemolytic uremic syndrome.
Wengenroth M, Hoeltje J, Repenthin J, Meyer TN, Bonk F, Becker H, Faiss S, Stammel O, Urban PP, Bruening R., AJNR Am J Neuroradiol 34(5), 2013
PMID: 23306013

Associations of age and sex with the clinical outcome and incubation period of Shiga toxin-producing Escherichia coli O104:H4 infections, 2011.
Werber D, King LA, Muller L, Follin P, Buchholz U, Bernard H, Rosner B, Ethelberg S, de Valk H, Hohle M., Am. J. Epidemiol. 178(6), 2013
PMID: 23935124

A new health threat in Europe: Shiga toxin-producing Escherichia coli O104:H4 infections.
Wu CJ, Hsueh PR, Ko WC., J Microbiol Immunol Infect 44(5), 2011
PMID: 21862425

Treatment of enterohemorrhagic Escherichia coli-induced hemolytic uremic syndrome (eHUS).
Wurzner R, Riedl M, Rosales A, Orth-Holler D., Semin. Thromb. Hemost. 40(4), 2014
PMID: 24802085

Real-time multiplex PCR for detecting Shiga toxin 2-producing Escherichia coli O104:H4 in human stools.
Zhang W, Bielaszewska M, Bauwens A, Fruth A, Mellmann A, Karch H., J. Clin. Microbiol. 50(5), 2012
PMID: 22337987

Lability of the pAA Virulence Plasmid in Escherichia coli O104:H4: Implications for Virulence in Humans.
Zhang W, Bielaszewska M, Kunsmann L, Mellmann A, Bauwens A, Kock R, Kossow A, Anders A, Gatermann S, Karch H., PLoS ONE 8(6), 2013
PMID: 23805269

The mosaic genome structure and phylogeny of Shiga toxin-producing Escherichia coli O104:H4 is driven by short-term adaptation.
Zhou K, Ferdous M, de Boer RF, Kooistra-Smid AM, Grundmann H, Friedrich AW, Rossen JW., Clin. Microbiol. Infect. 21(5), 2014
PMID: 25656624

Risk factors for development of hemolytic uremic syndrome in a cohort of adult patients with STEC 0104:H4 infection.
Zoufaly A, Cramer JP, Vettorazzi E, Sayk F, Bremer JP, Koop I, de Weerth A, Schmiedel S, Jordan S, Fraedrich K, Asselborn NH, Nitschke M, Neumann-Grutzeck C, Magnus T, Ruther C, Fellermann K, Stahl RK, Wegscheider K, Lohse AW., PLoS ONE 8(3), 2013
PMID: 23533606