Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

Gakidou E, Afshin A, Abajobir AA, Abate KH, Abbafati C, Abbas KM, Abd-Allah F, Abdulle AM, Abera SF, Aboyans V, Abu-Raddad LJ, et al. (2017)
LANCET 390(10100): 1345-1422.

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Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Abstract / Bemerkung
Background The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of risk factor exposure and attributable burden of disease. By providing estimates over a long time series, this study can monitor risk exposure trends critical to health surveillance and inform policy debates on the importance of addressing risks in context. Methods We used the comparative risk assessment framework developed for previous iterations of GBD to estimate levels and trends in exposure, attributable deaths, and attributable disability-adjusted life-years (DALYs), by age group, sex, year, and location for 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks from 1990 to 2016. This study included 481 risk-outcome pairs that met the GBD study criteria for convincing or probable evidence of causation. We extracted relative risk (RR) and exposure estimates from 22 717 randomised controlled trials, cohorts, pooled cohorts, household surveys, census data, satellite data, and other sources, according to the GBD 2016 source counting methods. Using the counterfactual scenario of theoretical minimum risk exposure level (TMREL), we estimated the portion of deaths and DALYs that could be attributed to a given risk. Finally, we explored four drivers of trends in attributable burden: population growth, population ageing, trends in risk exposure, and all other factors combined. Findings Since 1990, exposure increased significantly for 30 risks, did not change significantly for four risks, and decreased significantly for 31 risks. Among risks that are leading causes of burden of disease, child growth failure and household air pollution showed the most significant declines, while metabolic risks, such as body-mass index and high fasting plasma glucose, showed significant increases. In 2016, at Level 3 of the hierarchy, the three leading risk factors in terms of attributable DALYs at the global level for men were smoking (124.1 million DALYs [95% UI 111.2 million to 137.0 million]), high systolic blood pressure (122.2 million DALYs [110.3 million to 133.3 million], and low birthweight and short gestation (83.0 million DALYs [78.3 million to 87.7 million]), and for women, were high systolic blood pressure (89.9 million DALYs [80.9 million to 98.2 million]), high body-mass index (64.8 million DALYs [44.4 million to 87.6 million]), and high fasting plasma glucose (63.8 million DALYs [53.2 million to 76.3 million]). In 2016 in 113 countries, the leading risk factor in terms of attributable DALYs was a metabolic risk factor. Smoking remained among the leading five risk factors for DALYs for 109 countries, while low birthweight and short gestation was the leading risk factor for DALYs in 38 countries, particularly in sub-Saharan Africa and South Asia. In terms of important drivers of change in trends of burden attributable to risk factors, between 2006 and 2016 exposure to risks explains an 9.3% (6.9-11.6) decline in deaths and a 10.8% (8.3-13.1) decrease in DALYs at the global level, while population ageing accounts for 14.9% (12.7-17.5) of deaths and 6.2% (3.9-8.7) of DALYs, and population growth for 12.4% (10.1-14.9) of deaths and 12.4% (10.1-14.9) of DALYs. The largest contribution of trends in risk exposure to disease burden is seen between ages 1 year and 4 years, where a decline of 27.3% (24.9-29.7) of the change in DALYs between 2006 and 2016 can be attributed to declines in exposure to risks. Interpretation Increasingly detailed understanding of the trends in risk exposure and the RRs for each risk-outcome pair provide insights into both the magnitude of health loss attributable to risks and how modification of risk exposure has contributed to health trends. Metabolic risks warrant particular policy attention, due to their large contribution to global disease burden, increasing trends, and variable patterns across countries at the same level of development. GBD 2016 findings show that, while it has huge potential to improve health, risk modification has played a relatively small part in the past decade. Copyright (C) The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.


Gakidou E, Afshin A, Abajobir AA, et al. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. LANCET. 2017;390(10100):1345-1422.
Gakidou, E., Afshin, A., Abajobir, A. A., Abate, K. H., Abbafati, C., Abbas, K. M., Abd-Allah, F., et al. (2017). Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. LANCET, 390(10100), 1345-1422.
Gakidou, E., Afshin, A., Abajobir, A. A., Abate, K. H., Abbafati, C., Abbas, K. M., Abd-Allah, F., Abdulle, A. M., Abera, S. F., Aboyans, V., et al. (2017). Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. LANCET 390, 1345-1422.
Gakidou, E., et al., 2017. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. LANCET, 390(10100), p 1345-1422.
E. Gakidou, et al., “Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016”, LANCET, vol. 390, 2017, pp. 1345-1422.
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Burden of Disease Study 2016. LANCET. 390, 1345-1422 (2017).
Gakidou, Emmanuela, Afshin, Ashkan, Abajobir, Amanuel Alemu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M., Abd-Allah, Foad, Abdulle, Abdishakur M., Abera, Semaw Ferede, Aboyans, Victor, Abu-Raddad, Laith J., Abu-Rmeileh, Niveen M. 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K., Johnson, Catherine O., Jonas, Jost B., Jurisson, Mikk, Kabir, Zubair, Kadel, Rajendra, Kahsay, Amaha, Kamal, Ritul, Karch, Andre, Karema, Corine Kakizi, Kasaeian, Amir, Kassebaum, Nicholas J., Kastor, Anshul, Katikireddi, Srinivasa Vittal, Kawakami, Norito, Keiyoro, Peter Njenga, Kelbore, Sefonias Getachew, Kemmer, Laura, Kengne, Andre Pascal, Kesavachandran, Chandrasekharan Nair, Khader, Yousef Saleh, Khalil, Ibrahim A., Khan, Ejaz Ahmad, Khang, Young-Ho, Khosravi, Ardeshir, Khubchandani, Jagdish, Kieling, Christian, Kim, Daniel, Kim, Jun Y., Kim, Yun Jin, Kimokoti, Ruth W., Kinfu, Yohannes, Kisa, Adnan, Kissimova-Skarbek, Katarzyna A., Kivimaki, Mika, Knibbs, Luke D., Knudsen, Ann Kristin, Kopec, Jacek A., Kosen, Soewarta, Koul, Parvaiz A., Koyanagi, Ai, Kravchenko, Michael, Krohn, Kristopher J., Kromhout, Hans, Defo, Barthelemy Kuate, Bicer, Burcu Kucuk, Kumar, G. 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M., Mereta, Seid Tiku, Meretoja, Atte, Meretoja, Tuomo J., Mezgebe, Haftay Berhane, Micha, Renata, Millear, Anoushka, Miller, Ted R., Minnig, Shawn, Mirarefin, Mojde, Mirrakhimov, Erkin M., Misganaw, Awoke, Mishra, Shiva Raj, Mohammad, Karzan Abdulmuhsin, Mohammed, Kedir Endris, Mohammed, Shafiu, Ibrahim, Norlinah Mohamed, Mohan, Murali B. 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PMID: 29654047
Trends in future health financing and coverage: future health spending and universal health coverage in 188 countries, 2016-40.
Global Burden of Disease Health Financing Collaborator Network., Lancet 391(10132), 2018
PMID: 29678341
Identifying Unmet Treatment Needs for Patients With Osteoporotic Fracture: Feasibility Study for an Electronic Clinical Surveillance System.
Lin FC, Wang CY, Shang RJ, Hsiao FY, Lin MS, Hung KY, Wang J, Lin ZF, Lai F, Shen LJ, Huang CF., J Med Internet Res 20(4), 2018
PMID: 29691201
Long-Term Effects of Ambient Particulate Matter (With an Aerodynamic Diameter ≤2.5 μm) on Hypertension and Blood Pressure and Attributable Risk Among Reproductive-Age Adults in China.
Xie X, Wang Y, Yang Y, Xu J, Zhang Y, Tang W, Guo T, Wang Q, Shen H, Zhang Y, Yan D, Peng Z, Chen Y, He Y, Ma X., J Am Heart Assoc 7(9), 2018
PMID: 29700042
Generating the evidence for risk reduction: a contribution to the future of food-based dietary guidelines.
Schwingshackl L, Schlesinger S, Devleesschauwer B, Hoffmann G, Bechthold A, Schwedhelm C, Iqbal K, Knüppel S, Boeing H., Proc Nutr Soc 77(4), 2018
PMID: 29708078
Designing programs to improve diets for maternal and child health: estimating costs and potential dietary impacts of nutrition-sensitive programs in Ethiopia, Nigeria, and India.
Masters WA, Rosettie KL, Kranz S, Danaei G, Webb P, Mozaffarian D, Global Nutrition and Policy Consortium ., Health Policy Plan 33(4), 2018
PMID: 29522103
The Burden of Cardiovascular Diseases Among US States, 1990-2016.
Global Burden of Cardiovascular Diseases Collaboration, Roth GA, Johnson CO, Abate KH, Abd-Allah F, Ahmed M, Alam K, Alam T, Alvis-Guzman N, Ansari H, Ärnlöv J, Atey TM, Awasthi A, Awoke T, Barac A, Bärnighausen T, Bedi N, Bennett D, Bensenor I, Biadgilign S, Castañeda-Orjuela C, Catalá-López F, Davletov K, Dharmaratne S, Ding EL, Dubey M, Faraon EJA, Farid T, Farvid MS, Feigin V, Fernandes J, Frostad J, Gebru A, Geleijnse JM, Gona PN, Griswold M, Hailu GB, Hankey GJ, Hassen HY, Havmoeller R, Hay S, Heckbert SR, Irvine CMS, James SL, Jara D, Kasaeian A, Khan AR, Khera S, Khoja AT, Khubchandani J, Kim D, Kolte D, Lal D, Larsson A, Linn S, Lotufo PA, Magdy Abd El Razek H, Mazidi M, Meier T, Mendoza W, Mensah GA, Meretoja A, Mezgebe HB, Mirrakhimov E, Mohammed S, Moran AE, Nguyen G, Nguyen M, Ong KL, Owolabi M, Pletcher M, Pourmalek F, Purcell CA, Qorbani M, Rahman M, Rai RK, Ram U, Reitsma MB, Renzaho AMN, Rios-Blancas MJ, Safiri S, Salomon JA, Sartorius B, Sepanlou SG, Shaikh MA, Silva D, Stranges S, Tabarés-Seisdedos R, Tadele Atnafu N, Thakur JS, Topor-Madry R, Truelsen T, Tuzcu EM, Tyrovolas S, Ukwaja KN, Vasankari T, Vlassov V, Vollset SE, Wakayo T, Weintraub R, Wolfe C, Workicho A, Xu G, Yadgir S, Yano Y, Yip P, Yonemoto N, Younis M, Yu C, Zaidi Z, Zaki MES, Zipkin B, Afshin A, Gakidou E, Lim SS, Mokdad AH, Naghavi M, Vos T, Murray CJL., JAMA Cardiol 3(5), 2018
PMID: 29641820
Doctor is my blood pressure OK?
Green BB., J Hum Hypertens 32(7), 2018
PMID: 29713046
Visualized nutrition education and dietary behavioral change: A systematic review and meta-analysis.
Li X, Huang Y, Yin R, Pan C, Cai Y, Wang Z., Crit Rev Food Sci Nutr (), 2018
PMID: 29727198
Short-term abstinence from alcohol and changes in cardiovascular risk factors, liver function tests and cancer-related growth factors: a prospective observational study.
Mehta G, Macdonald S, Cronberg A, Rosselli M, Khera-Butler T, Sumpter C, Al-Khatib S, Jain A, Maurice J, Charalambous C, Gander A, Ju C, Hakan T, Sherwood R, Nair D, Jalan R, Moore KP., BMJ Open 8(5), 2018
PMID: 29730627
Greater coordination and harmonisation of European occupational cohorts is needed.
Turner MC, Mehlum IS., Occup Environ Med 75(7), 2018
PMID: 29735748
Identifying occupational carcinogens: an update from the IARC Monographs.
Loomis D, Guha N, Hall AL, Straif K., Occup Environ Med 75(8), 2018
PMID: 29769352
Wearable camera-derived microenvironments in relation to personal exposure to PM2.5.
Salmon M, Milà C, Bhogadi S, Addanki S, Madhira P, Muddepaka N, Mora A, Sanchez M, Kinra S, Sreekanth V, Doherty A, Marshall JD, Tonne C., Environ Int 117(), 2018
PMID: 29778830
Hypertension in HIV-Infected Adults: Novel Pathophysiologic Mechanisms.
Fahme SA, Bloomfield GS, Peck R., Hypertension 72(1), 2018
PMID: 29776989
Smoking, Blood Pressure, and Cardiovascular Disease Mortality in a Large Cohort of Chinese Men with 15 Years Follow-up.
Tan J, Zhang X, Wang W, Yin P, Guo X, Zhou M., Int J Environ Res Public Health 15(5), 2018
PMID: 29783678
The prevalence of substance use among Russian, Somali and Kurdish migrants in Finland: a population-based study.
Salama E, Niemelä S, Suvisaari J, Laatikainen T, Koponen P, Castaneda AE., BMC Public Health 18(1), 2018
PMID: 29788931
Disparities in Chronic Kidney Disease Prevalence among Males and Females in 195 Countries: Analysis of the Global Burden of Disease 2016 Study.
Bikbov B, Perico N, Remuzzi G, on behalf of the GBD Genitourinary Diseases Expert Group., Nephron 139(4), 2018
PMID: 29791905
Associations of Dairy Intake with Arterial Stiffness in Brazilian Adults: The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
Ribeiro AG, Mill JG, Cade NV, Velasquez-Melendez G, Matos SMA, Molina MDCB., Nutrients 10(6), 2018
PMID: 29857508
Promoting public health in nutrition: Nutri-Score and the tug of war between public health and the food industry.
Julia C, Charpak Y, Rusch E, Lecomte F, Lombrail P, Hercberg S., Eur J Public Health 28(3), 2018
PMID: 29554256
[Environmental burden of disease in Germany].
Tobollik M, Plaß D, Steckling N, Mertes H, Myck T, Ziese T, Wintermeyer D, Hornberg C., Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 61(6), 2018
PMID: 29700552
[Epidemiological studies with environmental relevance in Germany].
Schneider A, Rückerl R, Standl M, Markevych I, Hoffmann B, Moebus S, Jöckel KH, Weber A, Herr C, Heißenhuber A, Nennstiel-Ratzel U, Heinze S, Schulz C, Kolossa-Gehring M, Niemann H, Gößwald A, Schikowski T, Hüls A, Sugiri D, Peters A., Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 61(6), 2018
PMID: 29744533
Measuring and mapping the global burden of antimicrobial resistance.
Hay SI, Rao PC, Dolecek C, Day NPJ, Stergachis A, Lopez AD, Murray CJL., BMC Med 16(1), 2018
PMID: 29860943
The burden of Neglected Tropical Diseases in Brazil, 1990-2016: A subnational analysis from the Global Burden of Disease Study 2016.
Martins-Melo FR, Carneiro M, Ramos AN, Heukelbach J, Ribeiro ALP, Werneck GL., PLoS Negl Trop Dis 12(6), 2018
PMID: 29864133
Exposure to household air pollution from biomass-burning cookstoves and HbA1c and diabetic status among Honduran women.
Rajkumar S, Clark ML, Young BN, Benka-Coker ML, Bachand AM, Brook RD, Nelson TL, Volckens J, Reynolds SJ, L'Orange C, Good N, Koehler K, Africano S, Osorto Pinel AB, Peel JL., Indoor Air (), 2018
PMID: 29896912
Drinking patterns vary by gender, age and country-level income: Cross-country analysis of the International Alcohol Control Study.
Chaiyasong S, Huckle T, Mackintosh AM, Meier P, Parry CDH, Callinan S, Viet Cuong P, Kazantseva E, Gray-Phillip G, Parker K, Casswell S., Drug Alcohol Rev 37 Suppl 2(), 2018
PMID: 29900623
Changes in health in Belgium, 1990-2016: a benchmarking analysis based on the global burden of disease 2016 study.
Maertens de Noordhout C, Van Oyen H, Speybroeck N, Devleesschauwer B., BMC Public Health 18(1), 2018
PMID: 29925365
The socioeconomic profile of alcohol-attributable mortality in South Africa: a modelling study.
Probst C, Parry CDH, Wittchen HU, Rehm J., BMC Med 16(1), 2018
PMID: 29936909
Soot and the city: Evaluating the impacts of Clean Heat policies on indoor/outdoor air quality in New York City apartments.
Gould CF, Chillrud SN, Phillips D, Perzanowski MS, Hernández D., PLoS One 13(6), 2018
PMID: 29953529
Importance of Nutrients and Nutrient Metabolism on Human Health.
Chen Y, Michalak M, Agellon LB., Yale J Biol Med 91(2), 2018
PMID: 29955217
On the road to universal health care in Indonesia, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.
Mboi N, Murty Surbakti I, Trihandini I, Elyazar I, Houston Smith K, Bahjuri Ali P, Kosen S, Flemons K, Ray SE, Cao J, Glenn SD, Miller-Petrie MK, Mooney MD, Ried JL, Nur Anggraini Ningrum D, Idris F, Siregar KN, Harimurti P, Bernstein RS, Pangestu T, Sidharta Y, Naghavi M, Murray CJL, Hay SI., Lancet 392(10147), 2018
PMID: 29961639
Diagnosis and management of resistant hypertension: state of the art.
Wei FF, Zhang ZY, Huang QF, Staessen JA., Nat Rev Nephrol 14(7), 2018
PMID: 29700488
The transition to modernity and chronic disease: mismatch and natural selection.
Corbett S, Courtiol A, Lummaa V, Moorad J, Stearns S., Nat Rev Genet 19(7), 2018
PMID: 29743650
Reducing the health risks derived from exposure to addictive substances.
Anderson P, Gual A, Rehm J., Curr Opin Psychiatry 31(4), 2018
PMID: 29746421
Optimizing the delivery of interventions for harmful alcohol use in primary healthcare: an update.
Segura L, Anderson P, Gual A., Curr Opin Psychiatry 31(4), 2018
PMID: 29846264
Morbidity, mortality, and long-term consequences associated with diarrhoea from Cryptosporidium infection in children younger than 5 years: a meta-analyses study.
Khalil IA, Troeger C, Rao PC, Blacker BF, Brown A, Brewer TG, Colombara DV, De Hostos EL, Engmann C, Guerrant RL, Haque R, Houpt ER, Kang G, Korpe PS, Kotloff KL, Lima AAM, Petri WA, Platts-Mills JA, Shoultz DA, Forouzanfar MH, Hay SI, Reiner RC, Mokdad AH., Lancet Glob Health 6(7), 2018
PMID: 29903377
Determinants of smokeless tobacco use in India.
Thakur JS, Paika R., Indian J Med Res 148(1), 2018
PMID: 30264753
Unfavorable and favorable changes in modifiable risk factors and incidence of coronary heart disease: The Whitehall II cohort study.
Virtanen M, Vahtera J, Singh-Manoux A, Elovainio M, Ferrie JE, Kivimäki M., Int J Cardiol 269(), 2018
PMID: 30005835
Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
Merino J, Dashti HS, Li SX, Sarnowski C, Justice AE, Graff M, Papoutsakis C, Smith CE, Dedoussis GV, Lemaitre RN, Wojczynski MK, Männistö S, Ngwa JS, Kho M, Ahluwalia TS, Pervjakova N, Houston DK, Bouchard C, Huang T, Orho-Melander M, Frazier-Wood AC, Mook-Kanamori DO, Pérusse L, Pennell CE, de Vries PS, Voortman T, Li O, Kanoni S, Rose LM, Lehtimäki T, Zhao JH, Feitosa MF, Luan J, McKeown NM, Smith JA, Hansen T, Eklund N, Nalls MA, Rankinen T, Huang J, Hernandez DG, Schulz CA, Manichaikul A, Li-Gao R, Vohl MC, Wang CA, van Rooij FJA, Shin J, Kalafati IP, Day F, Ridker PM, Kähönen M, Siscovick DS, Langenberg C, Zhao W, Astrup A, Knekt P, Garcia M, Rao DC, Qi Q, Ferrucci L, Ericson U, Blangero J, Hofman A, Pausova Z, Mikkilä V, Wareham NJ, Kardia SLR, Pedersen O, Jula A, Curran JE, Zillikens MC, Viikari JS, Forouhi NG, Ordovás JM, Lieske JC, Rissanen H, Uitterlinden AG, Raitakari OT, Kiefte-de Jong JC, Dupuis J, Rotter JI, North KE, Scott RA, Province MA, Perola M, Cupples LA, Turner ST, Sørensen TIA, Salomaa V, Liu Y, Sung YJ, Qi L, Bandinelli S, Rich SS, de Mutsert R, Tremblay A, Oddy WH, Franco OH, Paus T, Florez JC, Deloukas P, Lyytikäinen LP, Chasman DI, Chu AY, Tanaka T., Mol Psychiatry (), 2018
PMID: 29988085
Effects of oils and solid fats on blood lipids: a systematic review and network meta-analysis.
Schwingshackl L, Bogensberger B, Benčič A, Knüppel S, Boeing H, Hoffmann G., J Lipid Res 59(9), 2018
PMID: 30006369
An overview of tenofovir and renal disease for the HIV-treating clinician.
Venter WDF, Fabian J, Feldman C., South Afr J HIV Med 19(1), 2018
PMID: 30167339
Dietary Antioxidants and Prevention of Non-Communicable Diseases.
Grosso G., Antioxidants (Basel) 7(7), 2018
PMID: 30029504
Social media use for nutrition outcomes in young adults: a mixed-methods systematic review.
Klassen KM, Douglass CH, Brennan L, Truby H, Lim MSC., Int J Behav Nutr Phys Act 15(1), 2018
PMID: 30041699
Motile Ciliary Disorders in Chronic Airway Inflammatory Diseases: Critical Target for Interventions.
Guan WJ, Peng Y, Zi XX, Tan KS, He TT, Zhong NS, Wang Y., Curr Allergy Asthma Rep 18(9), 2018
PMID: 30046922
Responsive and Equitable Health Systems-Partnership on Non-Communicable Diseases (RESPOND) study: a mixed-methods, longitudinal, observational study on treatment seeking for hypertension in Malaysia and the Philippines.
Palafox B, Seguin ML, McKee M, Dans AL, Yusoff K, Candari CJ, Idris K, Ismail JR, Krauss SE, Lasco G, Majid FA, Palileo-Villanueva LM, Razak AA, Renedo A, Balabanova D., BMJ Open 8(7), 2018
PMID: 30061449
'Buying Salad Is a Lot More Expensive than Going to McDonalds': Young Adults' Views about What Influences Their Food Choices.
Howse E, Hankey C, Allman-Farinelli M, Bauman A, Freeman B., Nutrients 10(8), 2018
PMID: 30061513
The WHO-ERS Smoking Cessation Training Project: the first year of experience.
Fu D, Gratziou C, Jiménez-Ruiz C, Faure M, Ward B, Ravara S, Prasad VM, Mauer-Stender K, Kaur J, Ciobanu A, Huq SM, Katsaounou P., ERJ Open Res 4(3), 2018
PMID: 30083549
The Global Nutrient Database: availability of macronutrients and micronutrients in 195 countries from 1980 to 2013.
Schmidhuber J, Sur P, Fay K, Huntley B, Salama J, Lee A, Cornaby L, Horino M, Murray C, Afshin A., Lancet Planet Health 2(8), 2018
PMID: 30082050
Cardiovascular Disease Prevention by Diet Modification: JACC Health Promotion Series.
Yu E, Malik VS, Hu FB., J Am Coll Cardiol 72(8), 2018
PMID: 30115231
Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial.
Webster R, Salam A, de Silva HA, Selak V, Stepien S, Rajapakse S, Amarasekara S, Amarasena N, Billot L, de Silva AP, Fernando M, Guggilla R, Jan S, Jayawardena J, Maulik PK, Mendis S, Mendis S, Munasinghe J, Naik N, Prabhakaran D, Ranasinghe G, Thom S, Tisserra N, Senaratne V, Wijekoon S, Wijeyasingam S, Rodgers A, Patel A, TRIUMPH Study Group., JAMA 320(6), 2018
PMID: 30120478
GDF15 deficiency promotes high fat diet-induced obesity in mice.
Tran T, Yang J, Gardner J, Xiong Y., PLoS One 13(8), 2018
PMID: 30070999
Social, Ecological, and Health Benefits of Clean Cooking.
Petach H, Williams KN, Mehta S., Ecohealth 15(4), 2018
PMID: 30083856
Impact of reducing portion sizes in worksite cafeterias: a stepped wedge randomised controlled pilot trial.
Hollands GJ, Cartwright E, Pilling M, Pechey R, Vasiljevic M, Jebb SA, Marteau TM., Int J Behav Nutr Phys Act 15(1), 2018
PMID: 30115084
Novel DNA Methylation Sites Influence GPR15 Expression in Relation to Smoking.
Haase T, Müller C, Krause J, Röthemeier C, Stenzig J, Kunze S, Waldenberger M, Münzel T, Pfeiffer N, Wild PS, Michal M, Marini F, Karakas M, Lackner KJ, Blankenberg S, Zeller T., Biomolecules 8(3), 2018
PMID: 30127295
Impact of glass shape on time taken to drink a soft drink: A laboratory-based experiment.
Langfield T, Pechey R, Pilling M, Marteau TM., PLoS One 13(8), 2018
PMID: 30148889
Association of job sectors with type 2 diabetes mellitus, hypercholesterolemia and obesity: a cross-sectional study from the Malaysian Cohort (TMC) project.
Borhanuddin B, Ahmad N, Shah SA, Murad NAA, Zakaria SZS, Kamaruddin MA, Jalal NA, Yusuf NAM, Patah AEA, Dauni A, Sallam WAFW, Jamal R., Int Health 10(5), 2018
PMID: 29462329
Perspective: Food-Based Dietary Guidelines in Europe-Scientific Concepts, Current Status, and Perspectives.
Bechthold A, Boeing H, Tetens I, Schwingshackl L, Nöthlings U., Adv Nutr 9(5), 2018
PMID: 30107475
Global burden of pain and global pain policy-creating a purposeful body of evidence.
Blyth FM, Huckel Schneider C., Pain 159 Suppl 1(), 2018
PMID: 30113946
Prevalence of Hypertension and Cardiovascular Risk According to Blood Pressure Thresholds Used for Diagnosis.
Lamprea-Montealegre JA, Zelnick LR, Hall YN, Bansal N, de Boer IH., Hypertension 72(3), 2018
PMID: 30354757
Food groups and intermediate disease markers: a systematic review and network meta-analysis of randomized trials.
Schwingshackl L, Hoffmann G, Iqbal K, Schwedhelm C, Boeing H., Am J Clin Nutr 108(3), 2018
PMID: 30535089
Blood Pressure Control and Cardiovascular Outcomes: Real-world Implications of the 2017 ACC/AHA Hypertension Guideline.
Lee JH, Kim SH, Kang SH, Cho JH, Cho Y, Oh IY, Yoon CH, Lee HY, Youn TJ, Chae IH, Kim CH., Sci Rep 8(1), 2018
PMID: 30177714
Progress toward eliminating TB and HIV deaths in Brazil, 2001-2015: a spatial assessment.
Ross JM, Henry NJ, Dwyer-Lindgren LA, de Paula Lobo A, Marinho de Souza F, Biehl MH, Ray SE, Reiner RC, Stubbs RW, Wiens KE, Earl L, Kutz MJ, Bhattacharjee NV, Kyu HH, Naghavi M, Hay SI., BMC Med 16(1), 2018
PMID: 30185204
The increasing burden of diabetes and variations among the states of India: the Global Burden of Disease Study 1990-2016.
India State-Level Disease Burden Initiative Diabetes Collaborators., Lancet Glob Health 6(12), 2018
PMID: 30219315
The burden of chronic respiratory diseases and their heterogeneity across the states of India: the Global Burden of Disease Study 1990-2016.
India State-Level Disease Burden Initiative CRD Collaborators., Lancet Glob Health 6(12), 2018
PMID: 30219316
The changing patterns of cardiovascular diseases and their risk factors in the states of India: the Global Burden of Disease Study 1990-2016.
India State-Level Disease Burden Initiative CVD Collaborators., Lancet Glob Health 6(12), 2018
PMID: 30219317
The burden of cancers and their variations across the states of India: the Global Burden of Disease Study 1990-2016.
India State-Level Disease Burden Initiative Cancer Collaborators., Lancet Oncol 19(10), 2018
PMID: 30219626
Outdoor particulate matter (PM10) exposure and lung cancer risk in the EAGLE study.
Consonni D, Carugno M, De Matteis S, Nordio F, Randi G, Bazzano M, Caporaso NE, Tucker MA, Bertazzi PA, Pesatori AC, Lubin JH, Landi MT., PLoS One 13(9), 2018
PMID: 30216350
Enhancing Behavior Change Technique Coding Methods: Identifying Behavioral Targets and Delivery Styles in Smoking Cessation Trials.
Black N, Williams AJ, Javornik N, Scott C, Johnston M, Eisma MC, Michie S, Hartmann-Boyce J, West R, Viechtbauer W, de Bruin M., Ann Behav Med (), 2018
PMID: 30239563
Cost-effectiveness of strategies to improve delivery of brief interventions for heavy drinking in primary care: results from the ODHIN trial.
Angus C, Li J, Romero-Rodriguez E, Anderson P, Parrott S, Brennan A., Eur J Public Health (), 2018
PMID: 30239676
The burden of musculoskeletal disorders in Mexico at national and state level, 1990-2016: estimates from the global burden of disease study 2016.
Clark P, Denova-Gutiérrez E, Razo C, Rios-Blancas MJ, Lozano R., Osteoporos Int 29(12), 2018
PMID: 30242448
Tuberculosis disease burden and attributable risk factors in Nigeria, 1990-2016.
Ogbo FA, Ogeleka P, Okoro A, Olusanya BO, Olusanya J, Ifegwu IK, Awosemo AO, Eastwood J, Page A., Trop Med Health 46(), 2018
PMID: 30262990
Integrated care for human immunodeficiency virus, diabetes and hypertension in Africa.
Garrib A, Birungi J, Lesikari S, Namakoola I, Njim T, Cuevas L, Niessen L, Mugisha K, Mutungi G, Mghamba J, Ramaiya K, Jaffar S, Mfinanga S, Nyirenda M., Trans R Soc Trop Med Hyg (), 2018
PMID: 30265362
Implications of the New American College of Cardiology Guidelines for Hypertension Prevalence in India.
Venkateshmurthy NS, Geldsetzer P, Jaacks LM, Prabhakaran D., JAMA Intern Med 178(10), 2018
PMID: 30083722
Rotavirus Vaccination and the Global Burden of Rotavirus Diarrhea Among Children Younger Than 5 Years.
Troeger C, Khalil IA, Rao PC, Cao S, Blacker BF, Ahmed T, Armah G, Bines JE, Brewer TG, Colombara DV, Kang G, Kirkpatrick BD, Kirkwood CD, Mwenda JM, Parashar UD, Petri WA, Riddle MS, Steele AD, Thompson RL, Walson JL, Sanders JW, Mokdad AH, Murray CJL, Hay SI, Reiner RC., JAMA Pediatr 172(10), 2018
PMID: 30105384
The association between blood pressure and long-term outcomes of patients with ischaemic cardiomyopathy with and without surgical revascularization: an analysis of the STICH trial.
Andersson B, She L, Tan RS, Jeemon P, Mokrzycki K, Siepe M, Romanov A, Favaloro LE, Djokovic LT, Raju PK, Betlejewski P, Racine N, Ostrzycki A, Nawarawong W, Das S, Rouleau JL, Sopko G, Lee KL, Velazquez EJ, Panza JA., Eur Heart J 39(37), 2018
PMID: 30113633
Short-Term Effects of Ambient Air Pollution on Hospitalization for Respiratory Disease in Taiyuan, China: A Time-Series Analysis.
Luo L, Zhang Y, Jiang J, Luan H, Yu C, Nan P, Luo B, You M., Int J Environ Res Public Health 15(10), 2018
PMID: 30275384
Estimates of the Global Burden of Ambient [Formula: see text], Ozone, and [Formula: see text] on Asthma Incidence and Emergency Room Visits.
Anenberg SC, Henze DK, Tinney V, Kinney PL, Raich W, Fann N, Malley CS, Roman H, Lamsal L, Duncan B, Martin RV, van Donkelaar A, Brauer M, Doherty R, Jonson JE, Davila Y, Sudo K, Kuylenstierna JCI., Environ Health Perspect 126(10), 2018
PMID: 30392403
Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016-40 for 195 countries and territories.
Foreman KJ, Marquez N, Dolgert A, Fukutaki K, Fullman N, McGaughey M, Pletcher MA, Smith AE, Tang K, Yuan CW, Brown JC, Friedman J, He J, Heuton KR, Holmberg M, Patel DJ, Reidy P, Carter A, Cercy K, Chapin A, Douwes-Schultz D, Frank T, Goettsch F, Liu PY, Nandakumar V, Reitsma MB, Reuter V, Sadat N, Sorensen RJD, Srinivasan V, Updike RL, York H, Lopez AD, Lozano R, Lim SS, Mokdad AH, Vollset SE, Murray CJL., Lancet 392(10159), 2018
PMID: 30340847
Changes in health in the countries of the UK and 150 English Local Authority areas 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.
Steel N, Ford JA, Newton JN, Davis ACJ, Vos T, Naghavi M, Glenn S, Hughes A, Dalton AM, Stockton D, Humphreys C, Dallat M, Schmidt J, Flowers J, Fox S, Abubakar I, Aldridge RW, Baker A, Brayne C, Brugha T, Capewell S, Car J, Cooper C, Ezzati M, Fitzpatrick J, Greaves F, Hay R, Hay S, Kee F, Larson HJ, Lyons RA, Majeed A, McKee M, Rawaf S, Rutter H, Saxena S, Sheikh A, Smeeth L, Viner RM, Vollset SE, Williams HC, Wolfe C, Woolf A, Murray CJL., Lancet 392(10158), 2018
PMID: 30497795
The Poorest of Poor Suffer the Greatest Burden From Smokeless Tobacco Use: A Study From 140 Countries.
Sinha DN, Gupta PC, Kumar A, Bhartiya D, Agarwal N, Sharma S, Singh H, Parascandola M, Mehrotra R., Nicotine Tob Res 20(12), 2018
PMID: 29309692
Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016: A Systematic Analysis for the Global Burden of Disease Study.
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