PUB - Publikationen an der Universität Bielefeld

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.
Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y, Chin LS, Choi A, Chu CT, Chung J, Clarke PG, Clark RS, Clarke SG, Clave C, Cleveland JL, Codogno P, Colombo MI, Coto-Montes A, Cregg JM, Cuervo AM, Debnath J, Demarchi F, Dennis PB, Dennis PA, Deretic V, Devenish RJ, Di Sano F, Dice JF, Difiglia M, Dinesh-Kumar S, Distelhorst CW, Djavaheri-Mergny M, Dorsey FC, Droge W, Dron M, Dunn WA Jr, Duszenko M, Eissa NT, Elazar Z, Esclatine A, Eskelinen EL, Fesus L, Finley KD, Fuentes JM, Fueyo J, Fujisaki K, Galliot B, Gao FB, Gewirtz DA, Gibson SB, Gohla A, Goldberg AL, Gonzalez R, Gonzalez-Estevez C, Gorski S, Gottlieb RA, Haussinger D, He YW, Heidenreich K, Hill JA, Hoyer-Hansen M, Hu X, Huang WP, Iwasaki A, Jaattela M, Jackson WT, Jiang X, Jin S, Johansen T, Jung JU, Kadowaki M, Kang C, Kelekar A, Kessel DH, Kiel JA, Kim HP, Kimchi A, Kinsella TJ, Kiselyov K, Kitamoto K, Knecht E, Komatsu M, Kominami E, Kondo S, Kovacs AL, Kroemer G, Kuan CY, Kumar R, Kundu M, Landry J, Laporte M, Le W, Lei HY, Lenardo MJ, Levine B, Lieberman A, Lim KL, Lin FC, Liou W, Liu LF, Lopez-Berestein G, Lopez-Otin C, Lu B, Macleod KF, Malorni W, Martinet W, Matsuoka K, Mautner J, Meijer AJ, Melendez A, Michels P, Miotto G, Mistiaen WP, Mizushima N, Mograbi B, Monastyrska I, Moore MN, Moreira PI, Moriyasu Y, Motyl T, Munz C, Murphy LO, Naqvi NI, Neufeld TP, Nishino I, Nixon RA, Noda T, Nurnberg B, Ogawa M, Oleinick NL, Olsen LJ, Ozpolat B, Paglin S, Palmer GE, Papassideri I, Parkes M, Perlmutter DH, Perry G, Piacentini M, Pinkas-Kramarski R, Prescott M, Proikas-Cezanne T, Raben N, Rami A, Reggiori F, Rohrer B, Rubinsztein DC, Ryan KM, Sadoshima J, Sakagami H, Sakai Y, Sandri M, Sasakawa C, Sass M, Schneider C, Seglen PO, Seleverstov O, Settleman J, Shacka JJ, Shapiro IM, Sibirny A, Silva-Zacarin EC, Simon HU, Simone C, Simonsen A, Smith MA, Spanel-Borowski K, Srinivas V, Steeves M, Stenmark H, Stromhaug PE, Subauste CS, Sugimoto S, Sulzer D, Suzuki T, Swanson MS, Tabas I, Takeshita F, Talbot NJ, Talloczy Z, Tanaka K, Tanaka K, Tanida I, Taylor GS, Taylor JP, Terman A, Tettamanti G, Thompson CB, Thumm M, Tolkovsky AM, Tooze SA, Truant R, Tumanovska LV, Uchiyama Y, Ueno T, Uzcategui NL, van der Klei I, Vaquero EC, Vellai T, Vogel MW, Wang HG, Webster P, Wiley JW, Xi Z, Xiao G, Yahalom J, Yang JM, Yap G, Yin XM, Yoshimori T, Yu L, Yue Z, Yuzaki M, Zabirnyk O, Zheng X, Zhu X, Deter RL., Autophagy 4(2), 2007
PMID: 18188003

Simultaneous activation of p38 and JNK by arachidonic acid stimulates the cytosolic phospholipase A2-dependent synthesis of lipid droplets in human monocytes.
Guijas C, Perez-Chacon G, Astudillo AM, Rubio JM, Gil-de-Gomez L, Balboa MA, Balsinde J., J. Lipid Res. 53(11), 2012
PMID: 22949356

The arachidonic acid pathway and its role in prostate cancer development and progression.
Patel MI, Kurek C, Dong Q., J. Urol. 179(5), 2008
PMID: 18343442

Lipid droplet biogenesis induced by stress involves triacylglycerol synthesis that depends on group VIA phospholipase A2.
Gubern A, Barcelo-Torns M, Casas J, Barneda D, Masgrau R, Picatoste F, Balsinde J, Balboa MA, Claro E., J. Biol. Chem. 284(9), 2008
PMID: 19117952

Group IVA phospholipase A(2) deficiency prevents CCl4-induced hepatic cell death through the enhancement of autophagy.
Ishihara K, Kanai S, Tanaka K, Kawashita E, Akiba S., Biochem. Biophys. Res. Commun. 471(1), 2016
PMID: 26850849

SnapShot: Lipid Droplets.
Krahmer N, Guo Y, Farese RV Jr, Walther TC., Cell 139(5), 2009
PMID: 19945384

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy.
Hardie DG., Nat. Rev. Mol. Cell Biol. 8(10), 2007
PMID: 17712357

Heparanase Enhances Tumor Growth and Chemoresistance by Promoting Autophagy.
Shteingauz A, Boyango I, Naroditsky I, Hammond E, Gruber M, Doweck I, Ilan N, Vlodavsky I., Cancer Res. 75(18), 2015
PMID: 26249176

Growth factor regulation of autophagy and cell survival in the absence of apoptosis.
Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T, Thompson CB., Cell 120(2), 2005
PMID: 15680329

Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis.
Nomura DK, Long JZ, Niessen S, Hoover HS, Ng SW, Cravatt BF., Cell 140(1), 2010
PMID: 20079333

Variable expression levels of keratin and vimentin reveal differential EMT status of circulating tumor cells and correlation with clinical characteristics and outcome of patients with metastatic breast cancer.
Polioudaki H, Agelaki S, Chiotaki R, Politaki E, Mavroudis D, Matikas A, Georgoulias V, Theodoropoulos PA., BMC Cancer 15(), 2015
PMID: 25962645

Perilipin-mediated lipid droplet formation in adipocytes promotes sterol regulatory element-binding protein-1 processing and triacylglyceride accumulation.
Takahashi Y, Shinoda A, Furuya N, Harada E, Arimura N, Ichi I, Fujiwara Y, Inoue J, Sato R., PLoS ONE 8(5), 2013
PMID: 23734208

The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes.
Berwick DC, Hers I, Heesom KJ, Moule SK, Tavare JM., J. Biol. Chem. 277(37), 2002
PMID: 12107176

Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance.
Zhou J, Farah BL, Sinha RA, Wu Y, Singh BK, Bay BH, Yang CS, Yen PM., PLoS ONE 9(1), 2014
PMID: 24489859

Sphingolipid storage affects autophagic metabolism of the amyloid precursor protein and promotes Abeta generation.
Tamboli IY, Hampel H, Tien NT, Tolksdorf K, Breiden B, Mathews PM, Saftig P, Sandhoff K, Walter J., J. Neurosci. 31(5), 2011
PMID: 21289194

Autophagy regulates lipid metabolism.
Singh R, Kaushik S, Wang Y, Xiang Y, Novak I, Komatsu M, Tanaka K, Cuervo AM, Czaja MJ., Nature 458(7242), 2009
PMID: 19339967

Prostaglandins and leukotrienes: advances in eicosanoid biology.
Funk CD., Science 294(5548), 2001
PMID: 11729303

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth.
Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, Romero IL, Carey MS, Mills GB, Hotamisligil GS, Yamada SD, Peter ME, Gwin K, Lengyel E., Nat. Med. 17(11), 2011
PMID: 22037646

Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development.
Baenke F, Peck B, Miess H, Schulze A., Dis Model Mech 6(6), 2013
PMID: 24203995

Lipid droplets in atherosclerotic fatty streaks of human aorta.
Lang PD, Insull W Jr., J. Clin. Invest. 49(8), 1970
PMID: 5431659

Autophagy: cellular and molecular mechanisms.
Glick D, Barth S, Macleod KF., J. Pathol. 221(1), 2010
PMID: 20225336

MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells.
Zirath H, Frenzel A, Oliynyk G, Segerstrom L, Westermark UK, Larsson K, Munksgaard Persson M, Hultenby K, Lehtio J, Einvik C, Pahlman S, Kogner P, Jakobsson PJ, Henriksson MA., Proc. Natl. Acad. Sci. U.S.A. 110(25), 2013
PMID: 23733953

Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies.
Chou TC., Pharmacol. Rev. 58(3), 2006
PMID: 16968952

The lipid phenotype of breast cancer cells characterized by Raman microspectroscopy: towards a stratification of malignancy.
Nieva C, Marro M, Santana-Codina N, Rao S, Petrov D, Sierra A., PLoS ONE 7(10), 2012
PMID: 23082122

Fast clearance of lipid droplets through MAP1S-activated autophagy suppresses clear cell renal cell carcinomas and promotes patient survival.
Xu G, Jiang Y, Xiao Y, Liu XD, Yue F, Li W, Li X, He Y, Jiang X, Huang H, Chen Q, Jonasch E, Liu L., Oncotarget 7(5), 2016
PMID: 26701856

Identification of novel autophagy regulators by a luciferase-based assay for the kinetics of autophagic flux.
Farkas T, Hoyer-Hansen M, Jaattela M., Autophagy 5(7), 2009
PMID: 19652534

Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis.
Brasaemle DL., J. Lipid Res. 48(12), 2007
PMID: 17878492

On the formation of lipid droplets in human adipocytes: the organization of the perilipin-vimentin cortex.
Heid H, Rickelt S, Zimbelmann R, Winter S, Schumacher H, Dorflinger Y, Kuhn C, Franke WW., PLoS ONE 9(2), 2014
PMID: 24587346

Lipid droplets: a new player in colorectal cancer stem cells unveiled by spectroscopic imaging.
Tirinato L, Liberale C, Di Franco S, Candeloro P, Benfante A, La Rocca R, Potze L, Marotta R, Ruffilli R, Rajamanickam VP, Malerba M, De Angelis F, Falqui A, Carbone E, Todaro M, Medema JP, Stassi G, Di Fabrizio E., Stem Cells 33(1), 2015
PMID: 25186497

Regulation of cytosolic phospholipase A2 phosphorylation by proteolytic cleavage of annexin A1 in activated mast cells.
Kwon JH, Lee JH, Kim KS, Chung YW, Kim IY., J. Immunol. 188(11), 2012
PMID: 22539796

Connexin 30 expression inhibits growth of human malignant gliomas but protects them against radiation therapy.
Artesi M, Kroonen J, Bredel M, Nguyen-Khac M, Deprez M, Schoysman L, Poulet C, Chakravarti A, Kim H, Scholtens D, Seute T, Rogister B, Bours V, Robe PA., Neuro-oncology 17(3), 2014
PMID: 25155356

Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites.
Pol A, Gross SP, Parton RG., J. Cell Biol. 204(5), 2014
PMID: 24590170

The role of lipid droplets in metabolic disease in rodents and humans.
Greenberg AS, Coleman RA, Kraemer FB, McManaman JL, Obin MS, Puri V, Yan QW, Miyoshi H, Mashek DG., J. Clin. Invest. 121(6), 2011
PMID: 21633178

Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis.
Kaushik S, Cuervo AM., Nat. Cell Biol. 17(6), 2015
PMID: 25961502

Integrated genomic analyses of ovarian carcinoma.
Cancer Genome Atlas Research Network, Bell D, Berchuck A, Birrer M, Chien J, Cramer D, Dao F, Dhir R, DiSaia P, Gabra H, Glenn P, Godwin A, Gross J, Hartmann L, Huang M, Huntsman D, Iacocca M, Imielinski M, Kalloger S, Karlan B, Levine D, Mills G, Morrison C, Mutch D, Olvera N, Orsulic S, Park K, Petrelli N, Rabeno B, Rader J, Sikic B, Smith-McCune K, Sood A, Bowtell D, Penny R, Testa J, Chang K, Dinh H, Drummond J, Fowler G, Gunaratne P, Hawes A, Kovar C, Lewis L, Morgan M, Newsham I, Santibanez J, Reid J, Trevino L, Wu Y-, Wang M, Muzny D, Wheeler D, Gibbs R, Getz G, Lawrence M, Cibulskis K, Sivachenko A, Sougnez C, Voet D, Wilkinson J, Bloom T, Ardlie K, Fennell T, Baldwin J, Gabriel S, Lander E, Ding LL, Fulton R, Koboldt D, McLellan M, Wylie T, Walker J, O'Laughlin M, Dooling D, Fulton L, Abbott R, Dees N, Zhang Q, Kandoth C, Wendl M, Schierding W, Shen D, Harris C, Schmidt H, Kalicki J, Delehaunty K, Fronick C, Demeter R, Cook L, Wallis J, Lin L, Magrini V, Hodges J, Eldred J, Smith S, Pohl C, Vandin F, Raphael B, Weinstock G, Mardis E, Wilson R, Meyerson M, Winckler W, Getz G, Verhaak R, Carter S, Mermel C, Saksena G, Nguyen H, Onofrio R, Lawrence M, Hubbard D, Gupta S, Crenshaw A, Ramos A, Ardlie K, Chin L, Protopopov A, Zhang J, Kim T, Perna I, Xiao Y, Zhang H, Ren G, Sathiamoorthy N, Park R, Lee E, Park P, Kucherlapati R, Absher M, Waite L, Sherlock G, Brooks J, Li J, Xu J, Myers R, Laird PW, Cope L, Herman J, Shen H, Weisenberger D, Noushmehr H, Pan F, Triche T Jr, Berman B, Van Den Berg D, Buckley J, Baylin S, Spellman P, Purdom E, Neuvial P, Bengtsson H, Jakkula L, Durinck S, Han J, Dorton S, Marr H, Choi Y, Wang V, Wang N, Ngai J, Conboy J, Parvin B, Feiler H, Speed T, Gray J, Levine A, Socci N, Liang Y, Taylor B, Schultz N, Borsu L, Lash A, Brennan C, Viale A, Sander C, Ladanyi M, Hoadley K, Meng S, Du Y, Shi Y, Li L, Turman Y, Zang D, Helms E, Balu S, Zhou X, Wu J, Topal M, Hayes D, Perou C, Getz G, Voet D, Saksena G, Zhang J, Zhang H, Wu C, Shukla S, Cibulskis K, Lawrence M, Sivachenko A, Jing R, Park R, Liu Y, Park P, Noble M, Chin L, Carter H, Kim D, Karchin R, Spellman P, Purdom E, Neuvial P, Bengtsson H, Durinck S, Han J, Korkola J, Heiser L, Cho R, Hu Z, Parvin B, Speed T, Gray J, Schultz N, Cerami E, Taylor B, Olshen A, Reva B, Antipin Y, Shen R, Mankoo P, Sheridan R, Ciriello G, Chang W, Bernanke J, Borsu L, Levine D, Ladanyi M, Sander C, Haussler D, Benz C, Stuart J, Benz S, Sanborn J, Vaske C, Zhu J, Szeto C, Scott G, Yau C, Hoadley K, Du Y, Balu S, Hayes D, Perou C, Wilkerson M, Zhang N, Akbani R, Baggerly K, Yung W, Mills G, Weinstein J, Penny R, Shelton T, Grimm D, Hatfield M, Morris S, Yena P, Rhodes P, Sherman M, Paulauskis J, Millis S, Kahn A, Greene J, Sfeir R, Jensen M, Chen J, Whitmore J, Alonso S, Jordan J, Chu A, Zhang J, Barker A, Compton C, Eley G, Ferguson M, Fielding P, Gerhard D, Myles R, Schaefer C, Mills Shaw K, Vaught J, Vockley J, Good P, Guyer M, Ozenberger B, Peterson J, Thomson E., Nature 474(7353), 2011
PMID: 21720365

Loss of HSulf-1 expression enhances tumorigenicity by inhibiting Bim expression in ovarian cancer.
He X, Khurana A, Roy D, Kaufmann S, Shridhar V., Int. J. Cancer 135(8), 2014
PMID: 24596063

HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer.
Mondal S, Roy D, Camacho-Pereira J, Khurana A, Chini E, Yang L, Baddour J, Stilles K, Padmabandu S, Leung S, Kalloger S, Gilks B, Lowe V, Dierks T, Hammond E, Dredge K, Nagrath D, Shridhar V., Oncotarget 6(32), 2015
PMID: 26378042

PPARγ maintains ERBB2-positive breast cancer stem cells.
Wang X, Sun Y, Wong J, Conklin DS., Oncogene 32(49), 2013
PMID: 23770845

Proline oxidase-adipose triglyceride lipase pathway restrains adipose cell death and tissue inflammation.
Lettieri Barbato D, Aquilano K, Baldelli S, Cannata SM, Bernardini S, Rotilio G, Ciriolo MR., Cell Death Differ. 21(1), 2013
PMID: 24096872

Perilipin family members preferentially sequester to either triacylglycerol-specific or cholesteryl-ester-specific intracellular lipid storage droplets.
Hsieh K, Lee YK, Londos C, Raaka BM, Dalen KT, Kimmel AR., J. Cell. Sci. 125(Pt 17), 2012
PMID: 22685330

Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes.
Zhang X, Zhang K., Biochem Res Int 2012(), 2012
PMID: 22506114

Cytosolic lipid droplets increase in size by microtubule-dependent complex formation.
Bostrom P, Rutberg M, Ericsson J, Holmdahl P, Andersson L, Frohman MA, Boren J, Olofsson SO., Arterioscler. Thromb. Vasc. Biol. 25(9), 2005
PMID: 16051877

Hormone-sensitive lipase: control of intracellular tri-(di-)acylglycerol and cholesteryl ester hydrolysis.
Kraemer FB, Shen WJ., J. Lipid Res. 43(10), 2002
PMID: 12364542

Enhancement of paclitaxel activity against hormone-refractory prostate cancer cells in vitro and in vivo by quinacrine.
de Souza PL, Castillo M, Myers CE., Br. J. Cancer 75(11), 1997
PMID: 9184173

The role of lipids in the control of autophagy.
Dall'Armi C, Devereaux KA, Di Paolo G., Curr. Biol. 23(1), 2013
PMID: 23305670

HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma.
Lai JP, Chien J, Strome SE, Staub J, Montoya DP, Greene EL, Smith DI, Roberts LR, Shridhar V., Oncogene 23(7), 2004
PMID: 14973553

Lipid Droplets: A Key Cellular Organelle Associated with Cancer Cell Survival under Normoxia and Hypoxia.
Koizume S, Miyagi Y., Int J Mol Sci 17(9), 2016
PMID: 27589734

Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer.
Lai J, Chien J, Staub J, Avula R, Greene EL, Matthews TA, Smith DI, Kaufmann SH, Roberts LR, Shridhar V., J. Biol. Chem. 278(25), 2003
PMID: 12686563

Properties of the Group IV phospholipase A2 family.
Ghosh M, Tucker DE, Burchett SA, Leslie CC., Prog. Lipid Res. 45(6), 2006
PMID: 16814865

cPLA2 phosphorylation at serine-515 and serine-505 is required for arachidonic acid release in vascular smooth muscle cells.
Pavicevic Z, Leslie CC, Malik KU., J. Lipid Res. 49(4), 2008
PMID: 18187403

Autophagic proteolysis of long-lived proteins in nonliver cells.
Roberts EA, Deretic V., Methods Mol. Biol. 445(), 2008
PMID: 18425445

Quinacrine promotes autophagic cell death and chemosensitivity in ovarian cancer and attenuates tumor growth.
Khurana A, Roy D, Kalogera E, Mondal S, Wen X, He X, Dowdy S, Shridhar V., Oncotarget 6(34), 2015
PMID: 26497553

Group IVA phospholipase A2 is necessary for the biogenesis of lipid droplets.
Gubern A, Casas J, Barcelo-Torns M, Barneda D, de la Rosa X, Masgrau R, Picatoste F, Balsinde J, Balboa MA, Claro E., J. Biol. Chem. 283(41), 2008
PMID: 18632668

Epigenetic regulation of autophagy by the methyltransferase G9a.
Artal-Martinez de Narvajas A, Gomez TS, Zhang JS, Mann AO, Taoda Y, Gorman JA, Herreros-Villanueva M, Gress TM, Ellenrieder V, Bujanda L, Kim DH, Kozikowski AP, Koenig A, Billadeau DD., Mol. Cell. Biol. 33(20), 2013
PMID: 23918802

PG545, a heparan sulfate mimetic, reduces heparanase expression in vivo, blocks spontaneous metastases and enhances overall survival in the 4T1 breast carcinoma model.
Hammond E, Brandt R, Dredge K., PLoS ONE 7(12), 2012
PMID: 23300607

Drug combination studies and their synergy quantification using the Chou-Talalay method.
Chou TC., Cancer Res. 70(2), 2010
PMID: 20068163

Perifosine induces protective autophagy and upregulation of ATG5 in human chronic myelogenous leukemia cells in vitro.
Tong Y, Liu YY, You LS, Qian WB., Acta Pharmacol. Sin. 33(4), 2012
PMID: 22407228

How to interpret LC3 immunoblotting.
Mizushima N, Yoshimori T., Autophagy 3(6), 2007
PMID: 17611390

Breaking the Barrier--Chaperone-Mediated Autophagy of Perilipins Regulates the Lipolytic Degradation of Fat.
Schweiger M, Zechner R., Cell Metab. 22(1), 2015
PMID: 26154053

Epigenetic silencing of HSulf-1 in ovarian cancer:implications in chemoresistance.
Staub J, Chien J, Pan Y, Qian X, Narita K, Aletti G, Scheerer M, Roberts LR, Molina J, Shridhar V., Oncogene 26(34), 2007
PMID: 17310998

Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer.
Roy D, Mondal S, Wang C, He X, Khurana A, Giri S, Hoffmann R, Jung DB, Kim SH, Chini EN, Periera JC, Folmes CD, Mariani A, Dowdy SC, Bakkum-Gamez JN, Riska SM, Oberg AL, Karoly ED, Bell LN, Chien J, Shridhar V., Cancer Metab 2(), 2014
PMID: 25225614

Autophagy in malignant transformation and cancer progression.
Galluzzi L, Pietrocola F, Bravo-San Pedro JM, Amaravadi RK, Baehrecke EH, Cecconi F, Codogno P, Debnath J, Gewirtz DA, Karantza V, Kimmelman A, Kumar S, Levine B, Maiuri MC, Martin SJ, Penninger J, Piacentini M, Rubinsztein DC, Simon HU, Simonsen A, Thorburn AM, Velasco G, Ryan KM, Kroemer G., EMBO J. 34(7), 2015
PMID: 25712477

Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes.
Subramanian V, Rothenberg A, Gomez C, Cohen AW, Garcia A, Bhattacharyya S, Shapiro L, Dolios G, Wang R, Lisanti MP, Brasaemle DL., J. Biol. Chem. 279(40), 2004
PMID: 15292255

Lipid droplets in inflammation and cancer.
Bozza PT, Viola JP., Prostaglandins Leukot. Essent. Fatty Acids 82(4-6), 2010
PMID: 20206487

PG545 enhances anti-cancer activity of chemotherapy in ovarian models and increases surrogate biomarkers such as VEGF in preclinical and clinical plasma samples.
Winterhoff B, Freyer L, Hammond E, Giri S, Mondal S, Roy D, Teoman A, Mullany SA, Hoffmann R, von Bismarck A, Chien J, Block MS, Millward M, Bampton D, Dredge K, Shridhar V., Eur. J. Cancer 51(7), 2015
PMID: 25754234

Lipid droplet-associated PAT-proteins show frequent and differential expression in neoplastic steatogenesis.
Straub BK, Herpel E, Singer S, Zimbelmann R, Breuhahn K, Macher-Goeppinger S, Warth A, Lehmann-Koch J, Longerich T, Heid H, Schirmacher P., Mod. Pathol. 23(3), 2010
PMID: 20081801

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP.
Porstmann T, Griffiths B, Chung YL, Delpuech O, Griffiths JR, Downward J, Schulze A., Oncogene 24(43), 2005
PMID: 16007182

A review on the monoacylglycerol lipase: at the interface between fat and endocannabinoid signalling.
Labar G, Wouters J, Lambert DM., Curr. Med. Chem. 17(24), 2010
PMID: 20491633

Lipophagy: connecting autophagy and lipid metabolism.
Singh R, Cuervo AM., Int J Cell Biol 2012(), 2012
PMID: 22536247

Diacylglycerol enrichment of endoplasmic reticulum or lipid droplets recruits perilipin 3/TIP47 during lipid storage and mobilization.
Skinner JR, Shew TM, Schwartz DM, Tzekov A, Lepus CM, Abumrad NA, Wolins NE., J. Biol. Chem. 284(45), 2009
PMID: 19748893

HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma.
Qiu B, Ackerman D, Sanchez DJ, Li B, Ochocki JD, Grazioli A, Bobrovnikova-Marjon E, Diehl JA, Keith B, Simon MC., Cancer Discov 5(6), 2015
PMID: 25829424