Revisiting regulation of potassium homeostasis in Escherichia coli: the connection to phosphate limitation
Schramke H, Laermann V, Tegetmeyer H, Brachmann A, Jung K, Altendorf K (2017)
MicrobiologyOpen 6(3): e00438.
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Autor*in
Schramke, Hannah;
Laermann, Vera;
Tegetmeyer, HalinaUniBi ;
Brachmann, Andreas;
Jung, Kirsten;
Altendorf, Karlheinz
Einrichtung
Abstract / Bemerkung
Two-component signal transduction constitutes the predominant strategy used by bacteria to adapt to fluctuating environments. The KdpD/KdpE system is one of the most widespread, and is crucial for K+ homeostasis. In Escherichia coli, the histidine kinase KdpD senses K+ availability, whereas the response regulator KdpE activates synthesis of the high-affinity K+ uptake system KdpFABC. Here we show that, in the absence of KdpD, kdpFABC expression can be activated via phosphorylation of KdpE by the histidine kinase PhoR. PhoR and its cognate response regulator PhoB comprise a phosphate-responsive two-component system, which senses phosphate limitation indirectly through the phosphate transporter PstCAB and its accessory protein PhoU. In vivo two-hybrid interaction studies based on the bacterial adenylate cyclase reveal pairwise interactions between KdpD, PhoR, and PhoU. Finally, we demonstrate that cross-regulation between the kdpFABC and pstSCAB operons occurs in both directions under simultaneous K+ and phosphate limitation, both in vitro and in vivo. This study for the first time demonstrates direct coupling between intracellular K+ and phosphate homeostasis and provides a mechanism for fine-tuning of the balance between positively and negatively charged ions in the bacterial cell.
Erscheinungsjahr
2017
Zeitschriftentitel
MicrobiologyOpen
Band
6
Ausgabe
3
Art.-Nr.
e00438
Urheberrecht / Lizenzen
ISSN
2045-8827
Page URI
https://pub.uni-bielefeld.de/record/2908402
Zitieren
Schramke H, Laermann V, Tegetmeyer H, Brachmann A, Jung K, Altendorf K. Revisiting regulation of potassium homeostasis in Escherichia coli: the connection to phosphate limitation. MicrobiologyOpen. 2017;6(3): e00438.
Schramke, H., Laermann, V., Tegetmeyer, H., Brachmann, A., Jung, K., & Altendorf, K. (2017). Revisiting regulation of potassium homeostasis in Escherichia coli: the connection to phosphate limitation. MicrobiologyOpen, 6(3), e00438. doi:10.1002/mbo3.438
Schramke, Hannah, Laermann, Vera, Tegetmeyer, Halina, Brachmann, Andreas, Jung, Kirsten, and Altendorf, Karlheinz. 2017. “Revisiting regulation of potassium homeostasis in Escherichia coli: the connection to phosphate limitation”. MicrobiologyOpen 6 (3): e00438.
Schramke, H., Laermann, V., Tegetmeyer, H., Brachmann, A., Jung, K., and Altendorf, K. (2017). Revisiting regulation of potassium homeostasis in Escherichia coli: the connection to phosphate limitation. MicrobiologyOpen 6:e00438.
Schramke, H., et al., 2017. Revisiting regulation of potassium homeostasis in Escherichia coli: the connection to phosphate limitation. MicrobiologyOpen, 6(3): e00438.
H. Schramke, et al., “Revisiting regulation of potassium homeostasis in Escherichia coli: the connection to phosphate limitation”, MicrobiologyOpen, vol. 6, 2017, : e00438.
Schramke, H., Laermann, V., Tegetmeyer, H., Brachmann, A., Jung, K., Altendorf, K.: Revisiting regulation of potassium homeostasis in Escherichia coli: the connection to phosphate limitation. MicrobiologyOpen. 6, : e00438 (2017).
Schramke, Hannah, Laermann, Vera, Tegetmeyer, Halina, Brachmann, Andreas, Jung, Kirsten, and Altendorf, Karlheinz. “Revisiting regulation of potassium homeostasis in Escherichia coli: the connection to phosphate limitation”. MicrobiologyOpen 6.3 (2017): e00438.
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Daten bereitgestellt von Europe PubMed Central.
Coordinated regulation of transcription by CcpA and the Staphylococcus aureus two-component system HptRS.
Reed JM, Olson S, Brees DF, Griffin CE, Grove RA, Davis PJ, Kachman SD, Adamec J, Somerville GA., PLoS One 13(12), 2018
PMID: 30540769
Reed JM, Olson S, Brees DF, Griffin CE, Grove RA, Davis PJ, Kachman SD, Adamec J, Somerville GA., PLoS One 13(12), 2018
PMID: 30540769
Regulation of potassium dependent ATPase (kdp) operon of Deinococcus radiodurans.
Dani P, Ujaoney AK, Apte SK, Basu B., PLoS One 12(12), 2017
PMID: 29206865
Dani P, Ujaoney AK, Apte SK, Basu B., PLoS One 12(12), 2017
PMID: 29206865
78 References
Daten bereitgestellt von Europe PubMed Central.
Comparative analysis of prototype two-component systems with either bifunctional or monofunctional sensors: differences in molecular structure and physiological function.
Alves R, Savageau MA., Mol. Microbiol. 48(1), 2003
PMID: 12657043
Alves R, Savageau MA., Mol. Microbiol. 48(1), 2003
PMID: 12657043
Nucleotide sequence of the genes involved in phosphate transport and regulation of the phosphate regulon in Escherichia coli.
Amemura M, Makino K, Shinagawa H, Kobayashi A, Nakata A., J. Mol. Biol. 184(2), 1985
PMID: 2993631
Amemura M, Makino K, Shinagawa H, Kobayashi A, Nakata A., J. Mol. Biol. 184(2), 1985
PMID: 2993631
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection.
Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, Datsenko KA, Tomita M, Wanner BL, Mori H., Mol. Syst. Biol. 2(), 2006
PMID: 16738554
Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, Datsenko KA, Tomita M, Wanner BL, Mori H., Mol. Syst. Biol. 2(), 2006
PMID: 16738554
The complete genome sequence of Escherichia coli K-12.
Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y., Science 277(5331), 1997
PMID: 9278503
Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y., Science 277(5331), 1997
PMID: 9278503
Trimmomatic: a flexible trimmer for Illumina sequence data.
Bolger AM, Lohse M, Usadel B., Bioinformatics 30(15), 2014
PMID: 24695404
Bolger AM, Lohse M, Usadel B., Bioinformatics 30(15), 2014
PMID: 24695404
The last generation of bacterial growth in limiting nutrient.
Bren A, Hart Y, Dekel E, Koster D, Alon U., BMC Syst Biol 7(), 2013
PMID: 23531321
Bren A, Hart Y, Dekel E, Koster D, Alon U., BMC Syst Biol 7(), 2013
PMID: 23531321
The Pho regulon and the pathogenesis of Escherichia coli.
Crepin S, Chekabab SM, Le Bihan G, Bertrand N, Dozois CM, Harel J., Vet. Microbiol. 153(1-2), 2011
PMID: 21700403
Crepin S, Chekabab SM, Le Bihan G, Bertrand N, Dozois CM, Harel J., Vet. Microbiol. 153(1-2), 2011
PMID: 21700403
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products.
Datsenko KA, Wanner BL., Proc. Natl. Acad. Sci. U.S.A. 97(12), 2000
PMID: 10829079
Datsenko KA, Wanner BL., Proc. Natl. Acad. Sci. U.S.A. 97(12), 2000
PMID: 10829079
Evolutionary insight from whole-genome sequencing of experimentally evolved microbes.
Dettman JR, Rodrigue N, Melnyk AH, Wong A, Bailey SF, Kassen R., Mol. Ecol. 21(9), 2012
PMID: 22332770
Dettman JR, Rodrigue N, Melnyk AH, Wong A, Bailey SF, Kassen R., Mol. Ecol. 21(9), 2012
PMID: 22332770
The roles and regulation of potassium in bacteria.
Epstein W., Prog. Nucleic Acid Res. Mol. Biol. 75(), 2003
PMID: 14604015
Epstein W., Prog. Nucleic Acid Res. Mol. Biol. 75(), 2003
PMID: 14604015
Potassium transport loci in Escherichia coli K-12.
Epstein W, Kim BS., J. Bacteriol. 108(2), 1971
PMID: 4942756
Epstein W, Kim BS., J. Bacteriol. 108(2), 1971
PMID: 4942756
A K+ transport ATPase in Escherichia coli.
Epstein W, Whitelaw V, Hesse J., J. Biol. Chem. 253(19), 1978
PMID: 211128
Epstein W, Whitelaw V, Hesse J., J. Biol. Chem. 253(19), 1978
PMID: 211128
Cross-talk between the histidine protein kinase VanS and the response regulator PhoB. Characterization and identification of a VanS domain that inhibits activation of PhoB.
Fisher SL, Jiang W, Wanner BL, Walsh CT., J. Biol. Chem. 270(39), 1995
PMID: 7559459
Fisher SL, Jiang W, Wanner BL, Walsh CT., J. Biol. Chem. 270(39), 1995
PMID: 7559459
A comprehensive toolbox for the rapid construction of lacZ fusion reporters.
Fried L, Lassak J, Jung K., J. Microbiol. Methods 91(3), 2012
PMID: 23022912
Fried L, Lassak J, Jung K., J. Microbiol. Methods 91(3), 2012
PMID: 23022912
Temporal hierarchy of gene expression mediated by transcription factor binding affinity and activation dynamics.
Gao R, Stock AM., MBio 6(3), 2015
PMID: 26015501
Gao R, Stock AM., MBio 6(3), 2015
PMID: 26015501
The PhoU protein from Escherichia coli interacts with PhoR, PstB, and metals to form a phosphate-signaling complex at the membrane.
Gardner SG, Johns KD, Tanner R, McCleary WR., J. Bacteriol. 196(9), 2014
PMID: 24563032
Gardner SG, Johns KD, Tanner R, McCleary WR., J. Bacteriol. 196(9), 2014
PMID: 24563032
Transcriptional regulation of the Enterococcus faecium BM4147 vancomycin resistance gene cluster by the VanS-VanR two-component regulatory system in Escherichia coli K-12.
Haldimann A, Fisher SL, Daniels LL, Walsh CT, Wanner BL., J. Bacteriol. 179(18), 1997
PMID: 9294451
Haldimann A, Fisher SL, Daniels LL, Walsh CT, Wanner BL., J. Bacteriol. 179(18), 1997
PMID: 9294451
Reduction of turgor is not the stimulus for the sensor kinase KdpD of Escherichia coli.
Hamann K, Zimmann P, Altendorf K., J. Bacteriol. 190(7), 2008
PMID: 18245296
Hamann K, Zimmann P, Altendorf K., J. Bacteriol. 190(7), 2008
PMID: 18245296
The hydrophilic N-terminal domain complements the membrane-anchored C-terminal domain of the sensor kinase KdpD of Escherichia coli.
Heermann R, Altendorf K, Jung K., J. Biol. Chem. 275(22), 2000
PMID: 10747873
Heermann R, Altendorf K, Jung K., J. Biol. Chem. 275(22), 2000
PMID: 10747873
The N-terminal input domain of the sensor kinase KdpD of Escherichia coli stabilizes the interaction between the cognate response regulator KdpE and the corresponding DNA-binding site.
Heermann R, Altendorf K, Jung K., J. Biol. Chem. 278(51), 2003
PMID: 14534307
Heermann R, Altendorf K, Jung K., J. Biol. Chem. 278(51), 2003
PMID: 14534307
The universal stress protein UspC scaffolds the KdpD/KdpE signaling cascade of Escherichia coli under salt stress.
Heermann R, Weber A, Mayer B, Ott M, Hauser E, Gabriel G, Pirch T, Jung K., J. Mol. Biol. 386(1), 2008
PMID: 19101563
Heermann R, Weber A, Mayer B, Ott M, Hauser E, Gabriel G, Pirch T, Jung K., J. Mol. Biol. 386(1), 2008
PMID: 19101563
Simple generation of site-directed point mutations in the Escherichia coli chromosome using Red(R)/ET(R) Recombination.
Heermann R, Zeppenfeld T, Jung K., Microb. Cell Fact. 7(), 2008
PMID: 18435843
Heermann R, Zeppenfeld T, Jung K., Microb. Cell Fact. 7(), 2008
PMID: 18435843
Dynamics of an interactive network composed of a bacterial two-component system, a transporter and K+ as mediator.
Heermann R, Zigann K, Gayer S, Rodriguez-Fernandez M, Banga JR, Kremling A, Jung K., PLoS ONE 9(2), 2014
PMID: 24586952
Heermann R, Zigann K, Gayer S, Rodriguez-Fernandez M, Banga JR, Kremling A, Jung K., PLoS ONE 9(2), 2014
PMID: 24586952
ReadXplorer--visualization and analysis of mapped sequences.
Hilker R, Stadermann KB, Doppmeier D, Kalinowski J, Stoye J, Straube J, Winnebald J, Goesmann A., Bioinformatics 30(16), 2014
PMID: 24790157
Hilker R, Stadermann KB, Doppmeier D, Kalinowski J, Stoye J, Straube J, Winnebald J, Goesmann A., Bioinformatics 30(16), 2014
PMID: 24790157
Global regulation by the seven-component Pi signaling system.
Hsieh YJ, Wanner BL., Curr. Opin. Microbiol. 13(2), 2010
PMID: 20171928
Hsieh YJ, Wanner BL., Curr. Opin. Microbiol. 13(2), 2010
PMID: 20171928
Individual substitutions of clustered arginine residues of the sensor kinase KdpD of Escherichia coli modulate the ratio of kinase to phosphatase activity.
Jung K, Altendorf K., J. Biol. Chem. 273(41), 1998
PMID: 9756874
Jung K, Altendorf K., J. Biol. Chem. 273(41), 1998
PMID: 9756874
Truncation of amino acids 12-128 causes deregulation of the phosphatase activity of the sensor kinase KdpD of Escherichia coli.
Jung K, Altendorf K., J. Biol. Chem. 273(28), 1998
PMID: 9651326
Jung K, Altendorf K., J. Biol. Chem. 273(28), 1998
PMID: 9651326
Purification, reconstitution, and characterization of KdpD, the turgor sensor of Escherichia coli.
Jung K, Tjaden B, Altendorf K., J. Biol. Chem. 272(16), 1997
PMID: 9099740
Jung K, Tjaden B, Altendorf K., J. Biol. Chem. 272(16), 1997
PMID: 9099740
K+ and ionic strength directly influence the autophosphorylation activity of the putative turgor sensor KdpD of Escherichia coli.
Jung K, Veen M, Altendorf K., J. Biol. Chem. 275(51), 2000
PMID: 11016946
Jung K, Veen M, Altendorf K., J. Biol. Chem. 275(51), 2000
PMID: 11016946
Karimova, 2005
A bacterial two-hybrid system based on a reconstituted signal transduction pathway.
Karimova G, Pidoux J, Ullmann A, Ladant D., Proc. Natl. Acad. Sci. U.S.A. 95(10), 1998
PMID: 9576956
Karimova G, Pidoux J, Ullmann A, Ladant D., Proc. Natl. Acad. Sci. U.S.A. 95(10), 1998
PMID: 9576956
ATP-driven potassium transport in right-side-out membrane vesicles via the Kdp system of Escherichia coli.
Kollmann R, Altendorf K., Biochim. Biophys. Acta 1143(1), 1993
PMID: 8499455
Kollmann R, Altendorf K., Biochim. Biophys. Acta 1143(1), 1993
PMID: 8499455
Bacterial sensor kinases: diversity in the recognition of environmental signals.
Krell T, Lacal J, Busch A, Silva-Jimenez H, Guazzaroni ME, Ramos JL., Annu. Rev. Microbiol. 64(), 2010
PMID: 20825354
Krell T, Lacal J, Busch A, Silva-Jimenez H, Guazzaroni ME, Ramos JL., Annu. Rev. Microbiol. 64(), 2010
PMID: 20825354
The sensor kinase KdpD of Escherichia coli senses external K+.
Laermann V, Cudic E, Kipschull K, Zimmann P, Altendorf K., Mol. Microbiol. 88(6), 2013
PMID: 23651428
Laermann V, Cudic E, Kipschull K, Zimmann P, Altendorf K., Mol. Microbiol. 88(6), 2013
PMID: 23651428
Osmotic control of kdp operon expression in Escherichia coli.
Laimins LA, Rhoads DB, Epstein W., Proc. Natl. Acad. Sci. U.S.A. 78(1), 1981
PMID: 6787588
Laimins LA, Rhoads DB, Epstein W., Proc. Natl. Acad. Sci. U.S.A. 78(1), 1981
PMID: 6787588
The phosphate regulon and bacterial virulence: a regulatory network connecting phosphate homeostasis and pathogenesis.
Lamarche MG, Wanner BL, Crepin S, Harel J., FEMS Microbiol. Rev. 32(3), 2008
PMID: 18248418
Lamarche MG, Wanner BL, Crepin S, Harel J., FEMS Microbiol. Rev. 32(3), 2008
PMID: 18248418
EK2 derivatives of bacteriophage lambda useful in the cloning of DNA from higher organisms: the lambdagtWES system.
Leder P, Tiemeier D, Enquist L., Science 196(4286), 1977
PMID: 322278
Leder P, Tiemeier D, Enquist L., Science 196(4286), 1977
PMID: 322278
Protein measurement with the Folin phenol reagent.
LOWRY OH, ROSEBROUGH NJ, FARR AL, RANDALL RJ., J. Biol. Chem. 193(1), 1951
PMID: 14907713
LOWRY OH, ROSEBROUGH NJ, FARR AL, RANDALL RJ., J. Biol. Chem. 193(1), 1951
PMID: 14907713
Identification of the PhoB Regulon and Role of PhoU in the Phosphate Starvation Response of Caulobacter crescentus.
Lubin EA, Henry JT, Fiebig A, Crosson S, Laub MT., J. Bacteriol. 198(1), 2015
PMID: 26483520
Lubin EA, Henry JT, Fiebig A, Crosson S, Laub MT., J. Bacteriol. 198(1), 2015
PMID: 26483520
The phosphotransferase protein EIIA(Ntr) modulates the phosphate starvation response through interaction with histidine kinase PhoR in Escherichia coli.
Luttmann D, Gopel Y, Gorke B., Mol. Microbiol. 86(1), 2012
PMID: 22812494
Luttmann D, Gopel Y, Gorke B., Mol. Microbiol. 86(1), 2012
PMID: 22812494
Stimulation of the potassium sensor KdpD kinase activity by interaction with the phosphotransferase protein IIA(Ntr) in Escherichia coli.
Luttmann D, Heermann R, Zimmer B, Hillmann A, Rampp IS, Jung K, Gorke B., Mol. Microbiol. 72(4), 2009
PMID: 19400808
Luttmann D, Heermann R, Zimmer B, Hillmann A, Rampp IS, Jung K, Gorke B., Mol. Microbiol. 72(4), 2009
PMID: 19400808
Expression of the Kdp ATPase is consistent with regulation by turgor pressure.
Malli R, Epstein W., J. Bacteriol. 180(19), 1998
PMID: 9748442
Malli R, Epstein W., J. Bacteriol. 180(19), 1998
PMID: 9748442
Stimulus perception in bacterial signal-transducing histidine kinases.
Mascher T, Helmann JD, Unden G., Microbiol. Mol. Biol. Rev. 70(4), 2006
PMID: 17158704
Mascher T, Helmann JD, Unden G., Microbiol. Mol. Biol. Rev. 70(4), 2006
PMID: 17158704
Miller, 1972
Miller, 1992
Characterization of acetic acid-detoxifying Escherichia coli evolved under phosphate starvation conditions.
Moreau PL, Loiseau L., Microb. Cell Fact. 15(), 2016
PMID: 26895825
Moreau PL, Loiseau L., Microb. Cell Fact. 15(), 2016
PMID: 26895825
Photorhabdus luminescens genes induced upon insect infection.
Munch A, Stingl L, Jung K, Heermann R., BMC Genomics 9(), 2008
PMID: 18489737
Munch A, Stingl L, Jung K, Heermann R., BMC Genomics 9(), 2008
PMID: 18489737
The structural basis of ribosome activity in peptide bond synthesis.
Nissen P, Hansen J, Ban N, Moore PB, Steitz TA., Science 289(5481), 2000
PMID: 10937990
Nissen P, Hansen J, Ban N, Moore PB, Steitz TA., Science 289(5481), 2000
PMID: 10937990
A simplification of the protein assay method of Lowry et al. which is more generally applicable.
Peterson GL., Anal. Biochem. 83(2), 1977
PMID: 603028
Peterson GL., Anal. Biochem. 83(2), 1977
PMID: 603028
Determinants of specificity in two-component signal transduction.
Podgornaia AI, Laub MT., Curr. Opin. Microbiol. 16(2), 2013
PMID: 23352354
Podgornaia AI, Laub MT., Curr. Opin. Microbiol. 16(2), 2013
PMID: 23352354
Effect of glpT and glpD mutations on expression of the phoA gene in Escherichia coli.
Rao NN, Roberts MF, Torriani A, Yashphe J., J. Bacteriol. 175(1), 1993
PMID: 8416912
Rao NN, Roberts MF, Torriani A, Yashphe J., J. Bacteriol. 175(1), 1993
PMID: 8416912
ABC transporters: the power to change.
Rees DC, Johnson E, Lewinson O., Nat. Rev. Mol. Cell Biol. 10(3), 2009
PMID: 19234479
Rees DC, Johnson E, Lewinson O., Nat. Rev. Mol. Cell Biol. 10(3), 2009
PMID: 19234479
Two systems for the uptake of phosphate in Escherichia coli.
Rosenberg H, Gerdes RG, Chegwidden K., J. Bacteriol. 131(2), 1977
PMID: 328484
Rosenberg H, Gerdes RG, Chegwidden K., J. Bacteriol. 131(2), 1977
PMID: 328484
The Pho regulon: a huge regulatory network in bacteria.
Santos-Beneit F., Front Microbiol 6(), 2015
PMID: 25983732
Santos-Beneit F., Front Microbiol 6(), 2015
PMID: 25983732
The ImageJ ecosystem: An open platform for biomedical image analysis.
Schindelin J, Rueden CT, Hiner MC, Eliceiri KW., Mol. Reprod. Dev. 82(7-8), 2015
PMID: 26153368
Schindelin J, Rueden CT, Hiner MC, Eliceiri KW., Mol. Reprod. Dev. 82(7-8), 2015
PMID: 26153368
A Dual-Sensing Receptor Confers Robust Cellular Homeostasis.
Schramke H, Tostevin F, Heermann R, Gerland U, Jung K., Cell Rep 16(1), 2016
PMID: 27320909
Schramke H, Tostevin F, Heermann R, Gerland U, Jung K., Cell Rep 16(1), 2016
PMID: 27320909
Cellular applications of 31P and 13C nuclear magnetic resonance.
Shulman RG, Brown TR, Ugurbil K, Ogawa S, Cohen SM, den Hollander JA., Science 205(4402), 1979
PMID: 36664
Shulman RG, Brown TR, Ugurbil K, Ogawa S, Cohen SM, den Hollander JA., Science 205(4402), 1979
PMID: 36664
In vivo characterization of the type A and B vancomycin-resistant enterococci (VRE) VanRS two-component systems in Escherichia coli: a nonpathogenic model for studying the VRE signal transduction pathways.
Silva JC, Haldimann A, Prahalad MK, Walsh CT, Wanner BL., Proc. Natl. Acad. Sci. U.S.A. 95(20), 1998
PMID: 9751771
Silva JC, Haldimann A, Prahalad MK, Walsh CT, Wanner BL., Proc. Natl. Acad. Sci. U.S.A. 95(20), 1998
PMID: 9751771
Cross-talk suppression between the CpxA-CpxR and EnvZ-OmpR two-component systems in E. coli.
Siryaporn A, Goulian M., Mol. Microbiol. 70(2), 2008
PMID: 18761686
Siryaporn A, Goulian M., Mol. Microbiol. 70(2), 2008
PMID: 18761686
Two-component signal transduction pathways regulating growth and cell cycle progression in a bacterium: a system-level analysis.
Skerker JM, Prasol MS, Perchuk BS, Biondi EG, Laub MT., PLoS Biol. 3(10), 2005
PMID: 16176121
Skerker JM, Prasol MS, Perchuk BS, Biondi EG, Laub MT., PLoS Biol. 3(10), 2005
PMID: 16176121
Two-component signal transduction.
Stock AM, Robinson VL, Goudreau PN., Annu. Rev. Biochem. 69(), 2000
PMID: 10966457
Stock AM, Robinson VL, Goudreau PN., Annu. Rev. Biochem. 69(), 2000
PMID: 10966457
Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes.
Studier FW, Moffatt BA., J. Mol. Biol. 189(1), 1986
PMID: 3537305
Studier FW, Moffatt BA., J. Mol. Biol. 189(1), 1986
PMID: 3537305
Requirement of a large K+-uptake capacity and of extracytoplasmic protease activity for protamine resistance of Escherichia coli.
Stumpe S, Bakker EP., Arch. Microbiol. 167(2-3), 1997
PMID: 9133319
Stumpe S, Bakker EP., Arch. Microbiol. 167(2-3), 1997
PMID: 9133319
Clarification of the structural and functional features of the osmoregulated kdp operon of Escherichia coli.
Sugiura A, Nakashima K, Tanaka K, Mizuno T., Mol. Microbiol. 6(13), 1992
PMID: 1630316
Sugiura A, Nakashima K, Tanaka K, Mizuno T., Mol. Microbiol. 6(13), 1992
PMID: 1630316
Sensor complexes regulating two-component signal transduction.
Szurmant H, White RA, Hoch JA., Curr. Opin. Struct. Biol. 17(6), 2007
PMID: 17913492
Szurmant H, White RA, Hoch JA., Curr. Opin. Struct. Biol. 17(6), 2007
PMID: 17913492
31P nuclear magnetic resonance studies of bioenergetics and glycolysis in anaerobic Escherichia coli cells.
Ugurbil K, Rottenberg H, Glynn P, Shulman RG., Proc. Natl. Acad. Sci. U.S.A. 75(5), 1978
PMID: 27785
Ugurbil K, Rottenberg H, Glynn P, Shulman RG., Proc. Natl. Acad. Sci. U.S.A. 75(5), 1978
PMID: 27785
Phosphorus-31 nuclear magnetic resonance studies of bioenergetics in wild-type and adenosinetriphosphatase(1-) Escherichia coli cells.
Ugurbil K, Rottenberg H, Glynn P, Shulman RG., Biochemistry 21(5), 1982
PMID: 6462175
Ugurbil K, Rottenberg H, Glynn P, Shulman RG., Biochemistry 21(5), 1982
PMID: 6462175
Characterization of the KdpD protein, the sensor kinase of the K(+)-translocating Kdp system of Escherichia coli.
Voelkner P, Puppe W, Altendorf K., Eur. J. Biochem. 217(3), 1993
PMID: 8223625
Voelkner P, Puppe W, Altendorf K., Eur. J. Biochem. 217(3), 1993
PMID: 8223625
Mutational analysis of the Escherichia coli phosphate-specific transport system, a member of the traffic ATPase (or ABC) family of membrane transporters. A role for proline residues in transmembrane helices.
Webb DC, Rosenberg H, Cox GB., J. Biol. Chem. 267(34), 1992
PMID: 1447208
Webb DC, Rosenberg H, Cox GB., J. Biol. Chem. 267(34), 1992
PMID: 1447208
Cation transport in Escherichia coli. VII. Potassium requirement for phosphate uptake.
Weiden PL, Epstein W, Schultz SG., J. Gen. Physiol. 50(6), 1967
PMID: 5340610
Weiden PL, Epstein W, Schultz SG., J. Gen. Physiol. 50(6), 1967
PMID: 5340610
Genetic and biochemical dissection of a HisKA domain identifies residues required exclusively for kinase and phosphatase activities.
Willett JW, Kirby JR., PLoS Genet. 8(11), 2012
PMID: 23226719
Willett JW, Kirby JR., PLoS Genet. 8(11), 2012
PMID: 23226719
Characterization of two genetically separable inorganic phosphate transport systems in Escherichia coli.
Willsky GR, Malamy MH., J. Bacteriol. 144(1), 1980
PMID: 6998957
Willsky GR, Malamy MH., J. Bacteriol. 144(1), 1980
PMID: 6998957
Kinetic analysis by in vivo 31P nuclear magnetic resonance of internal Pi during the uptake of sn-glycerol-3-phosphate by the pho regulon-dependent Ugp system and the glp regulon-dependent GlpT system.
Xavier KB, Kossmann M, Santos H, Boos W., J. Bacteriol. 177(3), 1995
PMID: 7836304
Xavier KB, Kossmann M, Santos H, Boos W., J. Bacteriol. 177(3), 1995
PMID: 7836304
A transient interaction between two phosphorelay proteins trapped in a crystal lattice reveals the mechanism of molecular recognition and phosphotransfer in signal transduction.
Zapf J, Sen U, Madhusudan , Hoch JA, Varughese KI., Structure 8(8), 2000
PMID: 10997904
Zapf J, Sen U, Madhusudan , Hoch JA, Varughese KI., Structure 8(8), 2000
PMID: 10997904
Stochastic activation of the response regulator PhoB by noncognate histidine kinases
Zhou, Journal of Integrative Bioinformatics 2(), 2005
Zhou, Journal of Integrative Bioinformatics 2(), 2005
Membrane topology analysis of the sensor kinase KdpD of Escherichia coli.
Zimmann P, Puppe W, Altendorf K., J. Biol. Chem. 270(47), 1995
PMID: 7499326
Zimmann P, Puppe W, Altendorf K., J. Biol. Chem. 270(47), 1995
PMID: 7499326
The extension of the fourth transmembrane helix of the sensor kinase KdpD of Escherichia coli is involved in sensing.
Zimmann P, Steinbrugge A, Schniederberend M, Jung K, Altendorf K., J. Bacteriol. 189(20), 2007
PMID: 17704218
Zimmann P, Steinbrugge A, Schniederberend M, Jung K, Altendorf K., J. Bacteriol. 189(20), 2007
PMID: 17704218
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