Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study

Silventoinen K, Jelenkovic A, Sund R, Hur Y-M, Yokoyama Y, Honda C, Hjelmborg J vB, Moller S, Ooki S, Aaltonen S, Ji F, et al. (2016)
AMERICAN JOURNAL OF CLINICAL NUTRITION 104(2): 371-379.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Silventoinen, Karri; Jelenkovic, Aline; Sund, Reijo; Hur, Yoon-Mi; Yokoyama, Yoshie; Honda, Chika; Hjelmborg, Jacob vB; Moller, Soren; Ooki, Syuichi; Aaltonen, Sari; Ji, Fuling; Ning, Feng
Alle
Abstract / Bemerkung
Background: Both genetic and environmental factors are known to affect body mass index (BMI), but detailed understanding of how their effects differ during childhood and adolescence is lacking. Objectives: We analyzed the genetic and environmental contributions to BMI variation from infancy to early adulthood and the ways they differ by sex and geographic regions representing high (North America and Australia), moderate (Europe), and low levels (East Asia) of obesogenic environments. Design: Data were available for 87,782 complete twin pairs from 0.5 to 19.5 y of age from 45 cohorts. Analyses were based on 383,092 BMI measurements. Variation in BMI was decomposed into genetic and environmental components through genetic structural equation modeling. Results: The variance of BMI increased from 5 y of age along with increasing mean BMI. The proportion of BMI variation explained by additive genetic factors was lowest at 4 y of age in boys (a(2) = 0.42) and girls (a(2) = 0.41) and then generally increased to 0.75 in both sexes at 19 y of age. This was because of a stronger influence of environmental factors shared by co-twins in midchildhood. After 15 y of age, the effect of shared environment was not observed. The sex-specific expression of genetic factors was seen in infancy but was most prominent at 13 y of age and older. The variance of BMI was highest in North America and Australia and lowest in East Asia, but the relative proportion of genetic variation to total variation remained roughly similar across different regions. Conclusions: Environmental factors shared by co-twins affect BMI in childhood, but little evidence for their contribution was found in late adolescence. Our results suggest that genetic factors play a major role in the variation of BMI in adolescence among populations of different ethnicities exposed to different environmental factors related to obesity.
Stichworte
BMI; children; genetics; international comparisons; twins
Erscheinungsjahr
2016
Zeitschriftentitel
AMERICAN JOURNAL OF CLINICAL NUTRITION
Band
104
Ausgabe
2
Seite(n)
371-379
ISSN
0002-9165
eISSN
1938-3207
Page URI
https://pub.uni-bielefeld.de/record/2905969

Zitieren

Silventoinen K, Jelenkovic A, Sund R, et al. Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study. AMERICAN JOURNAL OF CLINICAL NUTRITION. 2016;104(2):371-379.
Silventoinen, K., Jelenkovic, A., Sund, R., Hur, Y. - M., Yokoyama, Y., Honda, C., Hjelmborg, J. vB., et al. (2016). Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study. AMERICAN JOURNAL OF CLINICAL NUTRITION, 104(2), 371-379. doi:10.3945/ajcn.116.130252
Silventoinen, Karri, Jelenkovic, Aline, Sund, Reijo, Hur, Yoon-Mi, Yokoyama, Yoshie, Honda, Chika, Hjelmborg, Jacob vB, et al. 2016. “Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study”. AMERICAN JOURNAL OF CLINICAL NUTRITION 104 (2): 371-379.
Silventoinen, K., Jelenkovic, A., Sund, R., Hur, Y. - M., Yokoyama, Y., Honda, C., Hjelmborg, J. vB., Moller, S., Ooki, S., Aaltonen, S., et al. (2016). Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study. AMERICAN JOURNAL OF CLINICAL NUTRITION 104, 371-379.
Silventoinen, K., et al., 2016. Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study. AMERICAN JOURNAL OF CLINICAL NUTRITION, 104(2), p 371-379.
K. Silventoinen, et al., “Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study”, AMERICAN JOURNAL OF CLINICAL NUTRITION, vol. 104, 2016, pp. 371-379.
Silventoinen, K., Jelenkovic, A., Sund, R., Hur, Y.-M., Yokoyama, Y., Honda, C., Hjelmborg, J. vB., Moller, S., Ooki, S., Aaltonen, S., Ji, F., Ning, F., Pang, Z., Rebato, E., Busjahn, A., Kandler, C., Saudino, K.J., Jang, K.L., Cozen, W., Hwang, A.E., Mack, T.M., Gao, W., Yu, C., Li, L., Corley, R.P., Huibregtse, B.M., Christensen, K., Skytthe, A., Kyvik, K.O., Derom, C.A., Vlietinck, R.F., Loos, R.J.F., Heikkila, K., Wardle, J., Llewellyn, C.H., Fisher, A., McAdams, T.A., Eley, T.C., Gregory, A.M., He, M., Ding, X., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A.D., Tarnoki, D.L., Stazi, M.A., Fagnani, C., D'Ippolito, C., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S.A., Klump, K.L., Silberg, J.L., Eaves, L.J., Maes, H.H., Krueger, R.F., McGue, M., Pahlen, S., Gatz, M., Butler, D.A., Bartels, M., van Beijsterveldt, T.C.E.M., Craig, J.M., Saffery, R., Freitas, D.L., Maia, J.A., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Martin, N.G., Medland, S.E., Montgomery, G.W., Chong, Y., Swan, G.E., Krasnow, R., Magnusson, P.K.E., Pedersen, N.L., Tynelius, P., Lichtenstein, P., Haworth, C.M.A., Plomin, R., Bayasgalan, G., Narandalai, D., Harden, K.P., Tucker-Drob, E.M., Oncel, S.Y., Aliev, F., Spector, T., Mangino, M., Lachance, G., Baker, L.A., Tuvblad, C., Duncan, G.E., Buchwald, D., Willemsen, G., Rasmussen, F., Goldberg, J.H., Sorensen, T.I.A., Boomsma, D.I., Kaprio, J.: Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study. AMERICAN JOURNAL OF CLINICAL NUTRITION. 104, 371-379 (2016).
Silventoinen, Karri, Jelenkovic, Aline, Sund, Reijo, Hur, Yoon-Mi, Yokoyama, Yoshie, Honda, Chika, Hjelmborg, Jacob vB, Moller, Soren, Ooki, Syuichi, Aaltonen, Sari, Ji, Fuling, Ning, Feng, Pang, Zengchang, Rebato, Esther, Busjahn, Andreas, Kandler, Christian, Saudino, Kimberly J., Jang, Kerry L., Cozen, Wendy, Hwang, Amie E., Mack, Thomas M., Gao, Wenjing, Yu, Canqing, Li, Liming, Corley, Robin P., Huibregtse, Brooke M., Christensen, Kaare, Skytthe, Axel, Kyvik, Kirsten O., Derom, Catherine A., Vlietinck, Robert F., Loos, Ruth J. F., Heikkila, Kauko, Wardle, Jane, Llewellyn, Clare H., Fisher, Abigail, McAdams, Tom A., Eley, Thalia C., Gregory, Alice M., He, Mingguang, Ding, Xiaohu, Bjerregaard-Andersen, Morten, Beck-Nielsen, Henning, Sodemann, Morten, Tarnoki, Adam D., Tarnoki, David L., Stazi, Maria A., Fagnani, Corrado, D'Ippolito, Cristina, Knafo-Noam, Ariel, Mankuta, David, Abramson, Lior, Burt, S. Alexandra, Klump, Kelly L., Silberg, Judy L., Eaves, Lindon J., Maes, Hermine H., Krueger, Robert F., McGue, Matt, Pahlen, Shandell, Gatz, Margaret, Butler, David A., Bartels, Meike, van Beijsterveldt, Toos C. E. M., Craig, Jeffrey M., Saffery, Richard, Freitas, Duarte L., Maia, Jose Antonio, Dubois, Lise, Boivin, Michel, Brendgen, Mara, Dionne, Ginette, Vitaro, Frank, Martin, Nicholas G., Medland, Sarah E., Montgomery, Grant W., Chong, Youngsook, Swan, Gary E., Krasnow, Ruth, Magnusson, Patrik K. E., Pedersen, Nancy L., Tynelius, Per, Lichtenstein, Paul, Haworth, Claire M. A., Plomin, Robert, Bayasgalan, Gombojav, Narandalai, Danshiitsoodol, Harden, K. Paige, Tucker-Drob, Elliot M., Oncel, Sevgi Y., Aliev, Fazil, Spector, Timothy, Mangino, Massimo, Lachance, Genevieve, Baker, Laura A., Tuvblad, Catherine, Duncan, Glen E., Buchwald, Dedra, Willemsen, Gonneke, Rasmussen, Finn, Goldberg, Jack H., Sorensen, Thorkild I. A., Boomsma, Dorret I., and Kaprio, Jaakko. “Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study”. AMERICAN JOURNAL OF CLINICAL NUTRITION 104.2 (2016): 371-379.

24 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Maternal Metabolomic Profile and Fetal Programming of Offspring Adiposity: Identification of Potentially Protective Lipid Metabolites.
Hellmuth C, Lindsay KL, Uhl O, Buss C, Wadhwa PD, Koletzko B, Entringer S., Mol Nutr Food Res 63(1), 2019
PMID: 29714050
Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis.
Voerman E, Santos S, Patro Golab B, Amiano P, Ballester F, Barros H, Bergström A, Charles MA, Chatzi L, Chevrier C, Chrousos GP, Corpeleijn E, Costet N, Crozier S, Devereux G, Eggesbø M, Ekström S, Fantini MP, Farchi S, Forastiere F, Georgiu V, Godfrey KM, Gori D, Grote V, Hanke W, Hertz-Picciotto I, Heude B, Hryhorczuk D, Huang RC, Inskip H, Iszatt N, Karvonen AM, Kenny LC, Koletzko B, Küpers LK, Lagström H, Lehmann I, Magnus P, Majewska R, Mäkelä J, Manios Y, McAuliffe FM, McDonald SW, Mehegan J, Mommers M, Morgen CS, Mori TA, Moschonis G, Murray D, Chaoimh CN, Nohr EA, Nybo Andersen AM, Oken E, Oostvogels AJJM, Pac A, Papadopoulou E, Pekkanen J, Pizzi C, Polanska K, Porta D, Richiardi L, Rifas-Shiman SL, Ronfani L, Santos AC, Standl M, Stoltenberg C, Thiering E, Thijs C, Torrent M, Tough SC, Trnovec T, Turner S, van Rossem L, von Berg A, Vrijheid M, Vrijkotte TGM, West J, Wijga A, Wright J, Zvinchuk O, Sørensen TIA, Lawlor DA, Gaillard R, Jaddoe VWV., PLoS Med 16(2), 2019
PMID: 30742624
Testing Bidirectional Associations Between Childhood Aggression and BMI: Results from Three Cohorts.
Derks IPM, Bolhuis K, Yalcin Z, Gaillard R, Hillegers MHJ, Larsson H, Lundström S, Lichtenstein P, van Beijsterveldt CEM, Bartels M, Boomsma DI, Tiemeier H, Jansen PW., Obesity (Silver Spring) 27(5), 2019
PMID: 30957987
Genetic predisposition to obesity, restrained eating and changes in body weight: a population-based prospective study.
Konttinen H, Llewellyn C, Silventoinen K, Joensuu A, Männistö S, Salomaa V, Jousilahti P, Kaprio J, Perola M, Haukkala A., Int J Obes (Lond) 42(4), 2018
PMID: 29158543
Twins as Participants in Randomized Controlled Trials: A Review of Published Literature.
Sumathipala A, Yelland L, Green D, Shepherd T, Jayaweera K, Ferreira P, Craig JM., Twin Res Hum Genet 21(1), 2018
PMID: 29282159
From fat cells through an obesity theory.
Sørensen TIA., Eur J Clin Nutr 72(10), 2018
PMID: 29535406
Differential models of twin correlations in skew for body-mass index (BMI).
Tsang S, Duncan GE, Dinescu D, Turkheimer E., PLoS One 13(3), 2018
PMID: 29590176
Recent advances in understanding body weight homeostasis in humans
Müller MJ, Geisler C, Heymsfield SB, Bosy-Westphal A., 2018
PMID: PPR41735
Recent advances in understanding body weight homeostasis in humans.
Müller MJ, Geisler C, Heymsfield SB, Bosy-Westphal A., F1000Res 7(), 2018
PMID: 30026913
Parents Matter: Associations of Parental BMI and Feeding Behaviors With Child BMI in Brazilian Preschool and School-Aged Children.
Warkentin S, Mais LA, Latorre MDRDO, Carnell S, Taddei JAAC., Front Nutr 5(), 2018
PMID: 30148134
Evidence for gene-environment correlation in child feeding: Links between common genetic variation for BMI in children and parental feeding practices.
Selzam S, McAdams TA, Coleman JRI, Carnell S, O'Reilly PF, Plomin R, Llewellyn CH., PLoS Genet 14(11), 2018
PMID: 30457987
Variation in the Heritability of Child Body Mass Index by Obesogenic Home Environment.
Schrempft S, van Jaarsveld CHM, Fisher A, Herle M, Smith AD, Fildes A, Llewellyn CH., JAMA Pediatr 172(12), 2018
PMID: 30285028
Contributions of polygenic risk for obesity to PTSD-related metabolic syndrome and cortical thickness.
Wolf EJ, Miller DR, Logue MW, Sumner J, Stoop TB, Leritz EC, Hayes JP, Stone A, Schichman SA, McGlinchey RE, Milberg WP, Miller MW., Brain Behav Immun 65(), 2017
PMID: 28579519
Catalase overexpression modulates metabolic parameters in a new 'stress-less' leptin-deficient mouse model.
Amos DL, Robinson T, Massie MB, Cook C, Hoffsted A, Crain C, Santanam N., Biochim Biophys Acta Mol Basis Dis 1863(9), 2017
PMID: 28645653
Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts.
Silventoinen K, Jelenkovic A, Sund R, Yokoyama Y, Hur YM, Cozen W, Hwang AE, Mack TM, Honda C, Inui F, Iwatani Y, Watanabe M, Tomizawa R, Pietiläinen KH, Rissanen A, Siribaddana SH, Hotopf M, Sumathipala A, Rijsdijk F, Tan Q, Zhang D, Pang Z, Piirtola M, Aaltonen S, Öncel SY, Aliev F, Rebato E, Hjelmborg JB, Christensen K, Skytthe A, Kyvik KO, Silberg JL, Eaves LJ, Cutler TL, Ordoñana JR, Sánchez-Romera JF, Colodro-Conde L, Song YM, Yang S, Lee K, Franz CE, Kremen WS, Lyons MJ, Busjahn A, Nelson TL, Whitfield KE, Kandler C, Jang KL, Gatz M, Butler DA, Stazi MA, Fagnani C, D'Ippolito C, Duncan GE, Buchwald D, Martin NG, Medland SE, Montgomery GW, Jeong HU, Swan GE, Krasnow R, Magnusson PK, Pedersen NL, Dahl Aslan AK, McAdams TA, Eley TC, Gregory AM, Tynelius P, Baker LA, Tuvblad C, Bayasgalan G, Narandalai D, Spector TD, Mangino M, Lachance G, Burt SA, Klump KL, Harris JR, Brandt I, Nilsen TS, Krueger RF, McGue M, Pahlen S, Corley RP, Huibregtse BM, Bartels M, van Beijsterveldt CE, Willemsen G, Goldberg JH, Rasmussen F, Tarnoki AD, Tarnoki DL, Derom CA, Vlietinck RF, Loos RJ, Hopper JL, Sung J, Maes HH, Turkheimer E, Boomsma DI, Sørensen TI, Kaprio J., Am J Clin Nutr 106(2), 2017
PMID: 28679550
The Genetic Background of Metabolic Trait Clusters in Children and Adolescents.
Silventoinen K, Gouveia É, Jelenkovic A, Maia J, Antunes AM, Pinheiro de Carvalho MAA, Brehm AM, Thomis M, Lefevre J, Kaprio J, Freitas D., Metab Syndr Relat Disord 15(7), 2017
PMID: 28727943
The contribution of genetics and environment to obesity.
Albuquerque D, Nóbrega C, Manco L, Padez C., Br Med Bull 123(1), 2017
PMID: 28910990

32 References

Daten bereitgestellt von Europe PubMed Central.

Variability in the heritability of body mass index: a systematic review and meta-regression.
Elks CE, den Hoed M, Zhao JH, Sharp SJ, Wareham NJ, Loos RJ, Ong KK., Front Endocrinol (Lausanne) 3(), 2012
PMID: 22645519
Increased genetic variance of BMI with a higher prevalence of obesity.
Rokholm B, Silventoinen K, Angquist L, Skytthe A, Kyvik KO, Sorensen TI., PLoS ONE 6(6), 2011
PMID: 21738588
From modeling to measurement: developmental trends in genetic influence on adiposity in childhood.
Llewellyn CH, Trzaskowski M, Plomin R, Wardle J., Obesity (Silver Spring) 22(7), 2014
PMID: 24760426
Associations between BMI and the FTO gene are age dependent: results from the GINI and LISA birth cohort studies up to age 6 years.
Rzehak P, Scherag A, Grallert H, Sausenthaler S, Koletzko S, Bauer CP, Schaaf B, von Berg A, Berdel D, Borte M, Herbarth O, Kramer U, Illig T, Wichmann HE, Hebebrand J, Heinrich J; GINI and LISA Study Group, Wichmann HE, Heinrich J, Schoetzau A, Popescu M, Mosetter M, Schindler J, Franke K, Laubereau B, Sausenthaler S, Thaqi A, Zirngibl A, Zutavern A, Filipiak B, Gehring U, Berdel D, von Berg A, Albrecht B, Baumgart A, Bollrath C, Buttner S, Diekamp S, Gross I, Jakob T, Klemke KK, Kurpiun KS, Mollemann M, Neususs J, Varhelyi A, Zorn C, Koletzko S, Reinhard D, Weigand H, Antonie I, Baumler-Merl B, Tasch C, Gohlert R, Sonnichsen C, Bauer CP, Grubl A, Bartels P, Brockow I, Hoffmann U, Lotzbeyer F, Mayrl R, Negele K, Schill EM, Wolf B, Kramer U, Link E, Sugiri D, Ranft U, Wichmann HE, Heinrich J, Bolte G, Belcredi P, Jacob B, Schoetzau A, Mosetter M, Schindler J, Hohnke A, Franke K, Laubereau B, Sausenthaler S, Thaqi A, Zirngibl A, Zutavern A, Borte M, Schulz R, Sierig G, Mirow K, Gebauer C, Schulze B, Hainich J, Sack U, Emmrich F, von Berg A, Scholten C, Bollrath C, Gross I, Mollemann M, Herbarth O, Diez U, Rehwagen M, Schlink SU, Franck U, Jorks A, Roder S, Lehmann I, Herberth G, Daegelmann C, Weiss M, Albert M, Fahlbusch B, Bischof W, Koch A, Kramer U, Link E, Ranft U, Schins R, Bauer CP, Brockow I, Grubl A, Ring J, Grosch J, Weidinger S., Obes Facts 3(3), 2010
PMID: 20616607
The bigger picture of FTO: the first GWAS-identified obesity gene.
Loos RJ, Yeo GS., Nat Rev Endocrinol 10(1), 2013
PMID: 24247219
Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project.
Jelenkovic A, Yokoyama Y, Sund R, Honda C, Bogl LH, Aaltonen S, Ji F, Ning F, Pang Z, Ordonana JR, Sanchez-Romera JF, Colodro-Conde L, Burt SA, Klump KL, Medland SE, Montgomery GW, Kandler C, McAdams TA, Eley TC, Gregory AM, Saudino KJ, Dubois L, Boivin M, Tarnoki AD, Tarnoki DL, Haworth CM, Plomin R, Oncel SY, Aliev F, Stazi MA, Fagnani C, D'Ippolito C, Craig JM, Saffery R, Siribaddana SH, Hotopf M, Sumathipala A, Rijsdijk F, Spector T, Mangino M, Lachance G, Gatz M, Butler DA, Bayasgalan G, Narandalai D, Freitas DL, Maia JA, Harden KP, Tucker-Drob EM, Kim B, Chong Y, Hong C, Shin HJ, Christensen K, Skytthe A, Kyvik KO, Derom CA, Vlietinck RF, Loos RJ, Cozen W, Hwang AE, Mack TM, He M, Ding X, Chang B, Silberg JL, Eaves LJ, Maes HH, Cutler TL, Hopper JL, Aujard K, Magnusson PK, Pedersen NL, Aslan AK, Song YM, Yang S, Lee K, Baker LA, Tuvblad C, Bjerregaard-Andersen M, Beck-Nielsen H, Sodemann M, Heikkila K, Tan Q, Zhang D, Swan GE, Krasnow R, Jang KL, Knafo-Noam A, Mankuta D, Abramson L, Lichtenstein P, Krueger RF, McGue M, Pahlen S, Tynelius P, Duncan GE, Buchwald D, Corley RP, Huibregtse BM, Nelson TL, Whitfield KE, Franz CE, Kremen WS, Lyons MJ, Ooki S, Brandt I, Nilsen TS, Inui F, Watanabe M, Bartels M, van Beijsterveldt TC, Wardle J, Llewellyn CH, Fisher A, Rebato E, Martin NG, Iwatani Y, Hayakawa K, Sung J, Harris JR, Willemsen G, Busjahn A, Goldberg JH, Rasmussen F, Hur YM, Boomsma DI, Sorensen TI, Kaprio J, Silventoinen K., Twin Res Hum Genet 18(5), 2015
PMID: 26337138
OpenMx: An Open Source Extended Structural Equation Modeling Framework.
Boker S, Neale M, Maes H, Wilde M, Spiegel M, Brick T, Spies J, Estabrook R, Kenny S, Bates T, Mehta P, Fox J., Psychometrika 76(2), 2011
PMID: 23258944
The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits.
Silventoinen K, Jelenkovic A, Sund R, Honda C, Aaltonen S, Yokoyama Y, Tarnoki AD, Tarnoki DL, Ning F, Ji F, Pang Z, Ordonana JR, Sanchez-Romera JF, Colodro-Conde L, Burt SA, Klump KL, Medland SE, Montgomery GW, Kandler C, McAdams TA, Eley TC, Gregory AM, Saudino KJ, Dubois L, Boivin M, Haworth CM, Plomin R, Oncel SY, Aliev F, Stazi MA, Fagnani C, D'Ippolito C, Craig JM, Saffery R, Siribaddana SH, Hotopf M, Sumathipala A, Spector T, Mangino M, Lachance G, Gatz M, Butler DA, Bayasgalan G, Narandalai D, Freitas DL, Maia JA, Harden KP, Tucker-Drob EM, Christensen K, Skytthe A, Kyvik KO, Hong C, Chong Y, Derom CA, Vlietinck RF, Loos RJ, Cozen W, Hwang AE, Mack TM, He M, Ding X, Chang B, Silberg JL, Eaves LJ, Maes HH, Cutler TL, Hopper JL, Aujard K, Magnusson PK, Pedersen NL, Aslan AK, Song YM, Yang S, Lee K, Baker LA, Tuvblad C, Bjerregaard-Andersen M, Beck-Nielsen H, Sodemann M, Heikkila K, Tan Q, Zhang D, Swan GE, Krasnow R, Jang KL, Knafo-Noam A, Mankuta D, Abramson L, Lichtenstein P, Krueger RF, McGue M, Pahlen S, Tynelius P, Duncan GE, Buchwald D, Corley RP, Huibregtse BM, Nelson TL, Whitfield KE, Franz CE, Kremen WS, Lyons MJ, Ooki S, Brandt I, Nilsen TS, Inui F, Watanabe M, Bartels M, van Beijsterveldt TC, Wardle J, Llewellyn CH, Fisher A, Rebato E, Martin NG, Iwatani Y, Hayakawa K, Rasmussen F, Sung J, Harris JR, Willemsen G, Busjahn A, Goldberg JH, Boomsma DI, Hur YM, Sorensen TI, Kaprio J., Twin Res Hum Genet 18(4), 2015
PMID: 26014041
Population genetic differentiation of height and body mass index across Europe.
Robinson MR, Hemani G, Medina-Gomez C, Mezzavilla M, Esko T, Shakhbazov K, Powell JE, Vinkhuyzen A, Berndt SI, Gustafsson S, Justice AE, Kahali B, Locke AE, Pers TH, Vedantam S, Wood AR, van Rheenen W, Andreassen OA, Gasparini P, Metspalu A, Berg LH, Veldink JH, Rivadeneira F, Werge TM, Abecasis GR, Boomsma DI, Chasman DI, de Geus EJ, Frayling TM, Hirschhorn JN, Hottenga JJ, Ingelsson E, Loos RJ, Magnusson PK, Martin NG, Montgomery GW, North KE, Pedersen NL, Spector TD, Speliotes EK, Goddard ME, Yang J, Visscher PM., Nat. Genet. 47(11), 2015
PMID: 26366552
A genome-wide association study of body mass index across early life and childhood.
Warrington NM, Howe LD, Paternoster L, Kaakinen M, Herrala S, Huikari V, Wu YY, Kemp JP, Timpson NJ, St Pourcain B, Davey Smith G, Tilling K, Jarvelin MR, Pennell CE, Evans DM, Lawlor DA, Briollais L, Palmer LJ., Int J Epidemiol 44(2), 2015
PMID: 25953783
Heritability of food preferences in young children.
Breen FM, Plomin R, Wardle J., Physiol. Behav. 88(4-5), 2006
PMID: 16750228
Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development.
Sovio U, Mook-Kanamori DO, Warrington NM, Lawrence R, Briollais L, Palmer CN, Cecil J, Sandling JK, Syvanen AC, Kaakinen M, Beilin LJ, Millwood IY, Bennett AJ, Laitinen J, Pouta A, Molitor J, Davey Smith G, Ben-Shlomo Y, Jaddoe VW, Palmer LJ, Pennell CE, Cole TJ, McCarthy MI, Jarvelin MR, Timpson NJ; Early Growth Genetics Consortium., PLoS Genet. 7(2), 2011
PMID: 21379325
Sex differences in heritability of BMI: a comparative study of results from twin studies in eight countries.
Schousboe K, Willemsen G, Kyvik KO, Mortensen J, Boomsma DI, Cornes BK, Davis CJ, Fagnani C, Hjelmborg J, Kaprio J, De Lange M, Luciano M, Martin NG, Pedersen N, Pietilainen KH, Rissanen A, Saarni S, Sorensen TI, Van Baal GC, Harris JR., Twin Res 6(5), 2003
PMID: 14624725
Epigenetic variation in monozygotic twins: a genome-wide analysis of DNA methylation in buccal cells.
van Dongen J, Ehli EA, Slieker RC, Bartels M, Weber ZM, Davies GE, Slagboom PE, Heijmans BT, Boomsma DI., Genes (Basel) 5(2), 2014
PMID: 24802513
Genetic and environmental contributions to food use patterns of young adult twins.
Keskitalo K, Silventoinen K, Tuorila H, Perola M, Pietilainen KH, Rissanen A, Kaprio J., Physiol. Behav. 93(1-2), 2007
PMID: 17897688
Genetic influences on the difference in variability of height, weight and body mass index between Caucasian and East Asian adolescent twins.
Hur YM, Kaprio J, Iacono WG, Boomsma DI, McGue M, Silventoinen K, Martin NG, Luciano M, Visscher PM, Rose RJ, He M, Ando J, Ooki S, Nonaka K, Lin CC, Lajunen HR, Cornes BK, Bartels M, van Beijsterveldt CE, Cherny SS, Mitchell K., Int J Obes (Lond) 32(10), 2008
PMID: 18779828
The genetic and environmental influences on childhood obesity: a systematic review of twin and adoption studies.
Silventoinen K, Rokholm B, Kaprio J, Sorensen TI., Int J Obes (Lond) 34(1), 2009
PMID: 19752881
Studies of twins indicate that genetics influence dietary intake.
Hasselbalch AL, Heitmann BL, Kyvik KO, Sorensen TI., J. Nutr. 138(12), 2008
PMID: 19022965
Genetic and environmental contributions to weight, height, and BMI from birth to 19 years of age: an international study of over 12,000 twin pairs.
Dubois L, Ohm Kyvik K, Girard M, Tatone-Tokuda F, Perusse D, Hjelmborg J, Skytthe A, Rasmussen F, Wright MJ, Lichtenstein P, Martin NG., PLoS ONE 7(2), 2012
PMID: 22347368
Genetic and Environmental Effects on Weight, Height, and BMI Under 18 Years in a Chinese Population-Based Twin Sample.
Liu Q, Yu C, Gao W, Cao W, Lyu J, Wang S, Pang Z, Cong L, Dong Z, Wu F, Wang H, Wu X, Jiang G, Wang B, Li L., Twin Res Hum Genet 18(5), 2015
PMID: 26379063
Genetic and environmental effects on body mass index during adolescence: a prospective study among Finnish twins.
Lajunen HR, Kaprio J, Keski-Rahkonen A, Rose RJ, Pulkkinen L, Rissanen A, Silventoinen K., Int J Obes (Lond) 33(5), 2009
PMID: 19337205
Childhood obesity in developing countries: epidemiology, determinants, and prevention.
Gupta N, Goel K, Shah P, Misra A., Endocr. Rev. 33(1), 2012
PMID: 22240243
Prevalence of childhood and adult obesity in the United States, 2011-2012.
Ogden CL, Carroll MD, Kit BK, Flegal KM., JAMA 311(8), 2014
PMID: 24570244
Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013.
Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, Mullany EC, Biryukov S, Abbafati C, Abera SF, Abraham JP, Abu-Rmeileh NM, Achoki T, AlBuhairan FS, Alemu ZA, Alfonso R, Ali MK, Ali R, Guzman NA, Ammar W, Anwari P, Banerjee A, Barquera S, Basu S, Bennett DA, Bhutta Z, Blore J, Cabral N, Nonato IC, Chang JC, Chowdhury R, Courville KJ, Criqui MH, Cundiff DK, Dabhadkar KC, Dandona L, Davis A, Dayama A, Dharmaratne SD, Ding EL, Durrani AM, Esteghamati A, Farzadfar F, Fay DF, Feigin VL, Flaxman A, Forouzanfar MH, Goto A, Green MA, Gupta R, Hafezi-Nejad N, Hankey GJ, Harewood HC, Havmoeller R, Hay S, Hernandez L, Husseini A, Idrisov BT, Ikeda N, Islami F, Jahangir E, Jassal SK, Jee SH, Jeffreys M, Jonas JB, Kabagambe EK, Khalifa SE, Kengne AP, Khader YS, Khang YH, Kim D, Kimokoti RW, Kinge JM, Kokubo Y, Kosen S, Kwan G, Lai T, Leinsalu M, Li Y, Liang X, Liu S, Logroscino G, Lotufo PA, Lu Y, Ma J, Mainoo NK, Mensah GA, Merriman TR, Mokdad AH, Moschandreas J, Naghavi M, Naheed A, Nand D, Narayan KM, Nelson EL, Neuhouser ML, Nisar MI, Ohkubo T, Oti SO, Pedroza A, Prabhakaran D, Roy N, Sampson U, Seo H, Sepanlou SG, Shibuya K, Shiri R, Shiue I, Singh GM, Singh JA, Skirbekk V, Stapelberg NJ, Sturua L, Sykes BL, Tobias M, Tran BX, Trasande L, Toyoshima H, van de Vijver S, Vasankari TJ, Veerman JL, Velasquez-Melendez G, Vlassov VV, Vollset SE, Vos T, Wang C, Wang X, Weiderpass E, Werdecker A, Wright JL, Yang YC, Yatsuya H, Yoon J, Yoon SJ, Zhao Y, Zhou M, Zhu S, Lopez AD, Murray CJ, Gakidou E., Lancet 384(9945), 2014
PMID: 24880830
Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth.
Elks CE, Loos RJ, Sharp SJ, Langenberg C, Ring SM, Timpson NJ, Ness AR, Davey Smith G, Dunger DB, Wareham NJ, Ong KK., PLoS Med. 7(5), 2010
PMID: 20520848
Theory and practice in quantitative genetics.
Posthuma D, Beem AL, de Geus EJ, van Baal GC, von Hjelmborg JB, Iachine I, Boomsma DI., Twin Res 6(5), 2003
PMID: 14624720
Obesity-associated variants within FTO form long-range functional connections with IRX3.
Smemo S, Tena JJ, Kim KH, Gamazon ER, Sakabe NJ, Gomez-Marin C, Aneas I, Credidio FL, Sobreira DR, Wasserman NF, Lee JH, Puviindran V, Tam D, Shen M, Son JE, Vakili NA, Sung HK, Naranjo S, Acemel RD, Manzanares M, Nagy A, Cox NJ, Hui CC, Gomez-Skarmeta JL, Nobrega MA., Nature 507(7492), 2014
PMID: 24646999
DNA methylation and gene expression patterns in adipose tissue differ significantly within young adult monozygotic BMI-discordant twin pairs.
Pietilainen KH, Ismail K, Jarvinen E, Heinonen S, Tummers M, Bollepalli S, Lyle R, Muniandy M, Moilanen E, Hakkarainen A, Lundbom J, Lundbom N, Rissanen A, Kaprio J, Ollikainen M., Int J Obes (Lond) 40(4), 2015
PMID: 26499446
Increasing genetic variance of body mass index during the Swedish obesity epidemic.
Rokholm B, Silventoinen K, Tynelius P, Gamborg M, Sorensen TI, Rasmussen F., PLoS ONE 6(11), 2011
PMID: 22087252
Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®
Quellen

PMID: 27413137
PubMed | Europe PMC

Suchen in

Google Scholar