Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain

Gazea M, Tasouri E, Tolve M, Bosch V, Kabanova A, Gojak C, Kurtulmus B, Novikov O, Spatz J, Pereira G, Hübner W, et al. (2015)
Developmental Biology 409(1): 55-71.

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DOI
Autor*in
Gazea, Mary; Tasouri, Evangelia; Tolve, Marianna; Bosch, Viktoria; Kabanova, Anna; Gojak, Christian; Kurtulmus, Bahtiyar; Novikov, Orna; Spatz, Joachim; Pereira, Gislene; Hübner, WolfgangUniBi ; Brodski, Claude
Alle
Einrichtung
Fakultät für Physik > AG Biomolekulare Photonik
Erscheinungsjahr
2015
Zeitschriftentitel
Developmental Biology
Band
409
Ausgabe
1
Seite(n)
55-71
ISSN
00121606
eISSN
1095-564X
Page URI
https://pub.uni-bielefeld.de/record/2786118

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Gazea M, Tasouri E, Tolve M, et al. Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. Developmental Biology. 2015;409(1):55-71.
Gazea, M., Tasouri, E., Tolve, M., Bosch, V., Kabanova, A., Gojak, C., Kurtulmus, B., et al. (2015). Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. Developmental Biology, 409(1), 55-71. doi:10.1016/j.ydbio.2015.10.033
Gazea, Mary, Tasouri, Evangelia, Tolve, Marianna, Bosch, Viktoria, Kabanova, Anna, Gojak, Christian, Kurtulmus, Bahtiyar, et al. 2015. “Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain”. Developmental Biology 409 (1): 55-71.
Gazea, M., Tasouri, E., Tolve, M., Bosch, V., Kabanova, A., Gojak, C., Kurtulmus, B., Novikov, O., Spatz, J., Pereira, G., et al. (2015). Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. Developmental Biology 409, 55-71.
Gazea, M., et al., 2015. Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. Developmental Biology, 409(1), p 55-71.
M. Gazea, et al., “Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain”, Developmental Biology, vol. 409, 2015, pp. 55-71.
Gazea, M., Tasouri, E., Tolve, M., Bosch, V., Kabanova, A., Gojak, C., Kurtulmus, B., Novikov, O., Spatz, J., Pereira, G., Hübner, W., Brodski, C., Tucker, K.L., Blaess, S.: Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. Developmental Biology. 409, 55-71 (2015).
Gazea, Mary, Tasouri, Evangelia, Tolve, Marianna, Bosch, Viktoria, Kabanova, Anna, Gojak, Christian, Kurtulmus, Bahtiyar, Novikov, Orna, Spatz, Joachim, Pereira, Gislene, Hübner, Wolfgang, Brodski, Claude, Tucker, Kerry L., and Blaess, Sandra. “Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain”. Developmental Biology 409.1 (2015): 55-71.

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Crosstalk of Intercellular Signaling Pathways in the Generation of Midbrain Dopaminergic Neurons In Vivo and from Stem Cells.
Brodski C, Blaess S, Partanen J, Prakash N., J Dev Biol 7(1), 2019
PMID: 30650592
Roles of Primary Cilia in the Developing Brain.
Park SM, Jang HJ, Lee JH., Front Cell Neurosci 13(), 2019
PMID: 31139054
A pilot study exploring the impact of cardiac medications on ciliary beat frequency: possible implications for clinical management.
Loomba RS, Bhushan A, Afolayan AJ., J Basic Clin Physiol Pharmacol 29(5), 2018
PMID: 29723155
LRRC45 contributes to early steps of axoneme extension.
Kurtulmus B, Yuan C, Schuy J, Neuner A, Hata S, Kalamakis G, Martin-Villalba A, Pereira G., J Cell Sci 131(18), 2018
PMID: 30131441
Specificity of Pitx3-Dependent Gene Regulatory Networks in Subsets of Midbrain Dopamine Neurons.
Bifsha P, Balsalobre A, Drouin J., Mol Neurobiol 54(7), 2017
PMID: 27514757
Targeting sonic hedgehog signaling in neurological disorders.
Patel SS, Tomar S, Sharma D, Mahindroo N, Udayabanu M., Neurosci Biobehav Rev 74(pt a), 2017
PMID: 28088536
Discovery, Diagnosis, and Etiology of Craniofacial Ciliopathies.
Schock EN, Brugmann SA., Cold Spring Harb Perspect Biol 9(9), 2017
PMID: 28213462
WDR8 is a centriolar satellite and centriole-associated protein that promotes ciliary vesicle docking during ciliogenesis.
Kurtulmus B, Wang W, Ruppert T, Neuner A, Cerikan B, Viol L, Dueñas-Sánchez R, Gruss OJ, Pereira G., J Cell Sci 129(3), 2016
PMID: 26675238
Neuropeptides shaping the central nervous system development: Spatiotemporal actions of VIP and PACAP through complementary signaling pathways.
Maduna T, Lelievre V., J Neurosci Res 94(12), 2016
PMID: 27717098
Definition of a critical spatiotemporal window within which primary cilia control midbrain dopaminergic neurogenesis.
Gazea M, Tasouri E, Heigl T, Bosch V, Tucker KL, Blaess S., Neurogenesis (Austin) 3(1), 2016
PMID: 28090543
Neuron's little helper: The role of primary cilia in neurogenesis.
Lepanto P, Badano JL, Zolessi FR., Neurogenesis (Austin) 3(1), 2016
PMID: 28090545
Primary Cilia Negatively Regulate Melanogenesis in Melanocytes and Pigmentation in a Human Skin Model.
Choi H, Shin JH, Kim ES, Park SJ, Bae IH, Jo YK, Jeong IY, Kim HJ, Lee Y, Park HC, Jeon HB, Kim KW, Lee TR, Cho DH., PLoS One 11(12), 2016
PMID: 27941997

83 References

Daten bereitgestellt von Europe PubMed Central.

Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development.
Lin W, Metzakopian E, Mavromatakis YE, Gao N, Balaskas N, Sasaki H, Briscoe J, Whitsett JA, Goulding M, Kaestner KH, Ang SL., Dev. Biol. 333(2), 2009
PMID: 19607821
Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling.
Blaess S, Stephen D, Joyner AL., Development 135(12), 2008
PMID: 18480159
Location and size of dopaminergic and serotonergic cell populations are controlled by the position of the midbrain-hindbrain organizer.
Brodski C, Weisenhorn DM, Signore M, Sillaber I, Oesterheld M, Broccoli V, Acampora D, Simeone A, Wurst W., J. Neurosci. 23(10), 2003
PMID: 12764108
A simple slice culture system for the imaging of nerve development in embryonic mouse.
Brachmann I, Jakubick VC, Shaked M, Unsicker K, Tucker KL., Dev. Dyn. 236(12), 2007
PMID: 18000984
Vertebrate Smoothened functions at the primary cilium.
Corbit KC, Aanstad P, Singla V, Norman AR, Stainier DY, Reiter JF., Nature 437(7061), 2005
PMID: 16136078
Dopamine neurons modulate neural encoding and expression of depression-related behaviour.
Tye KM, Mirzabekov JJ, Warden MR, Ferenczi EA, Tsai HC, Finkelstein J, Kim SY, Adhikari A, Thompson KR, Andalman AS, Gunaydin LA, Witten IB, Deisseroth K., Nature 493(7433), 2012
PMID: 23235822
Proliferation zones in the axolotl brain and regeneration of the telencephalon.
Maden M, Manwell LA, Ormerod BK., Neural Dev 8(), 2013
PMID: 23327114
Ftm is a novel basal body protein of cilia involved in Shh signalling.
Vierkotten J, Dildrop R, Peters T, Wang B, Ruther U., Development 134(14), 2007
PMID: 17553904
The graded response to Sonic Hedgehog depends on cilia architecture.
Caspary T, Larkins CE, Anderson KV., Dev. Cell 12(5), 2007
PMID: 17488627
Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway.
Jho EH, Zhang T, Domon C, Joo CK, Freund JN, Costantini F., Mol. Cell. Biol. 22(4), 2002
PMID: 11809808
Function and developmental origin of a mesocortical inhibitory circuit.
Kabanova A, Pabst M, Lorkowski M, Braganza O, Boehlen A, Nikbakht N, Pothmann L, Vaswani AR, Musgrove R, Di Monte DA, Sauvage M, Beck H, Blaess S., Nat. Neurosci. 18(6), 2015
PMID: 25961790
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function.
Haycraft CJ, Banizs B, Aydin-Son Y, Zhang Q, Michaud EJ, Yoder BK., PLoS Genet. 1(4), 2005
PMID: 16254602
Joubert syndrome and related disorders: spectrum of neuroimaging findings in 75 patients.
Poretti A, Huisman TA, Scheer I, Boltshauser E., AJNR Am J Neuroradiol 32(8), 2011
PMID: 21680654
Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification.
Motoyama J, Milenkovic L, Iwama M, Shikata Y, Scott MP, Hui CC., Dev. Biol. 259(1), 2003
PMID: 12812795
Cilia and Hedgehog responsiveness in the mouse.
Huangfu D, Anderson KV., Proc. Natl. Acad. Sci. U.S.A. 102(32), 2005
PMID: 16061793
FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate.
Ye W, Shimamura K, Rubenstein JL, Hynes MA, Rosenthal A., Cell 93(5), 1998
PMID: 9630220
Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity.
Mavromatakis YE, Lin W, Metzakopian E, Ferri AL, Yan CH, Sasaki H, Whisett J, Ang SL., Mech. Dev. 128(1-2), 2010
PMID: 21093585
Migratory defect of mesencephalic dopaminergic neurons in developing reeler mice.
Kang WY, Kim SS, Cho SK, Kim S, Suh-Kim H, Lee YD., Anat Cell Biol 43(3), 2010
PMID: 21212864
Cilia proteins control cerebellar morphogenesis by promoting expansion of the granule progenitor pool.
Chizhikov VV, Davenport J, Zhang Q, Shih EK, Cabello OA, Fuchs JL, Yoder BK, Millen KJ., J. Neurosci. 27(36), 2007
PMID: 17804638
Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development.
Tang M, Luo SX, Tang V, Huang EJ., Neural Dev 8(), 2013
PMID: 23618354
The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat.
Smith UM, Consugar M, Tee LJ, McKee BM, Maina EN, Whelan S, Morgan NV, Goranson E, Gissen P, Lilliquist S, Aligianis IA, Ward CJ, Pasha S, Punyashthiti R, Malik Sharif S, Batman PA, Bennett CP, Woods CG, McKeown C, Bucourt M, Miller CA, Cox P, Algazali L, Trembath RC, Torres VE, Attie-Bitach T, Kelly DA, Maher ER, Gattone VH 2nd, Harris PC, Johnson CA., Nat. Genet. 38(2), 2006
PMID: 16415887
The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance.
Pazour GJ, Baker SA, Deane JA, Cole DG, Dickert BL, Rosenbaum JL, Witman GB, Besharse JC., J. Cell Biol. 157(1), 2002
PMID: 11916979
Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development.
Corrales JD, Rocco GL, Blaess S, Guo Q, Joyner AL., Development 131(22), 2004
PMID: 15496441
Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development.
Fuccillo M, Joyner AL, Fishell G., Nat. Rev. Neurosci. 7(10), 2006
PMID: 16988653
A central region of Gli2 regulates its localization to the primary cilium and transcriptional activity.
Santos N, Reiter JF., J. Cell. Sci. 127(Pt 7), 2014
PMID: 24463817
Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum.
Lewis PM, Gritli-Linde A, Smeyne R, Kottmann A, McMahon AP., Dev. Biol. 270(2), 2004
PMID: 15183722
The functional anatomy of basal ganglia disorders.
Albin RL, Young AB, Penney JB., Trends Neurosci. 12(10), 1989
PMID: 2479133
Multiple essential roles for primary cilia in heart development.
Willaredt MA, Gorgas K, Gardner HA, Tucker KL., Cilia 1(1), 2012
PMID: 23351706
Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons.
Tang M, Miyamoto Y, Huang EJ., Development 136(12), 2009
PMID: 19439492
Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia.
Huang P, Schier AF., Development 136(18), 2009
PMID: 19700616
Cell-autonomous FGF signaling regulates anteroposterior patterning and neuronal differentiation in the mesodiencephalic dopaminergic progenitor domain.
Lahti L, Peltopuro P, Piepponen TP, Partanen J., Development 139(5), 2012
PMID: 22278924
A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene.
Hui CC, Joyner AL., Nat. Genet. 3(3), 1993
PMID: 8387379
Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling.
Breunig JJ, Sarkisian MR, Arellano JI, Morozov YM, Ayoub AE, Sojitra S, Wang B, Flavell RA, Rakic P, Town T., Proc. Natl. Acad. Sci. U.S.A. 105(35), 2008
PMID: 18728187
Primary cilia are not required for normal canonical Wnt signaling in the mouse embryo.
Ocbina PJ, Tuson M, Anderson KV., PLoS ONE 4(8), 2009
PMID: 19718259
Inversin, Wnt signaling and primary cilia.
Lienkamp S, Ganner A, Walz G., Differentiation 83(2), 2011
PMID: 22206729
The primary cilium: a signalling centre during vertebrate development.
Goetz SC, Anderson KV., Nat. Rev. Genet. 11(5), 2010
PMID: 20395968
Diverse roles for Wnt7a in ventral midbrain neurogenesis and dopaminergic axon morphogenesis.
Fernando CV, Kele J, Bye CR, Niclis JC, Alsanie W, Blakely BD, Stenman J, Turner BJ, Parish CL., Stem Cells Dev. 23(17), 2014
PMID: 24803261
Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells.
Han YG, Spassky N, Romaguera-Ros M, Garcia-Verdugo JM, Aguilar A, Schneider-Maunoury S, Alvarez-Buylla A., Nat. Neurosci. 11(3), 2008
PMID: 18297065
Joubert syndrome: brain and spinal cord malformations in genotyped cases and implications for neurodevelopmental functions of primary cilia.
Juric-Sekhar G, Adkins J, Doherty D, Hevner RF., Acta Neuropathol. 123(5), 2012
PMID: 22331178
All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3.
Bai CB, Stephen D, Joyner AL., Dev. Cell 6(1), 2004
PMID: 14723851
Transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo.
Farkas LM, Dunker N, Roussa E, Unsicker K, Krieglstein K., J. Neurosci. 23(12), 2003
PMID: 12832542
Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors.
Bonilla S, Hall AC, Pinto L, Attardo A, Gotz M, Huttner WB, Arenas E., Glia 56(8), 2008
PMID: 18351630
Patched1 regulates hedgehog signaling at the primary cilium.
Rohatgi R, Milenkovic L, Scott MP., Science 317(5836), 2007
PMID: 17641202
Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia.
Jeong J, Mao J, Tenzen T, Kottmann AH, McMahon AP., Genes Dev. 18(8), 2004
PMID: 15107405
Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain.
Prakash N, Puelles E, Freude K, Trumbach D, Omodei D, Di Salvio M, Sussel L, Ericson J, Sander M, Simeone A, Wurst W., Development 136(15), 2009
PMID: 19592574
Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon.
Nakatani T, Kumai M, Mizuhara E, Minaki Y, Ono Y., Dev. Biol. 339(1), 2009
PMID: 20035737
A crucial role for primary cilia in cortical morphogenesis.
Willaredt MA, Hasenpusch-Theil K, Gardner HA, Kitanovic I, Hirschfeld-Warneken VC, Gojak CP, Gorgas K, Bradford CL, Spatz J, Wolfl S, Theil T, Tucker KL., J. Neurosci. 28(48), 2008
PMID: 19036983
Intraflagellar transport.
Scholey JM., Annu. Rev. Cell Dev. Biol. 19(), 2003
PMID: 14570576
FGF signaling gradient maintains symmetrical proliferative divisions of midbrain neuronal progenitors.
Lahti L, Saarimaki-Vire J, Rita H, Partanen J., Dev. Biol. 349(2), 2010
PMID: 21074523
Hedgehog signalling in the mouse requires intraflagellar transport proteins.
Huangfu D, Liu A, Rakeman AS, Murcia NS, Niswander L, Anderson KV., Nature 426(6962), 2003
PMID: 14603322
Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region.
Blaess S, Corrales JD, Joyner AL., Development 133(9), 2006
PMID: 16571630
Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain.
Gorivodsky M, Mukhopadhyay M, Wilsch-Braeuninger M, Phillips M, Teufel A, Kim C, Malik N, Huttner W, Westphal H., Dev. Biol. 325(1), 2008
PMID: 18930042
Duration of Shh signaling contributes to mDA neuron diversity.
Hayes L, Ralls S, Wang H, Ahn S., Dev. Biol. 374(1), 2012
PMID: 23201023
Time of neuron origin and gradients of neurogenesis in midbrain dopaminergic neurons in the mouse.
Bayer SA, Wills KV, Triarhou LC, Ghetti B., Exp Brain Res 105(2), 1995
PMID: 7498372
Primary cilia and organogenesis: is Hedgehog the only sculptor?
Tasouri E, Tucker KL., Cell Tissue Res. 345(1), 2011
PMID: 21638207
Intraflagellar transport is essential for endochondral bone formation.
Haycraft CJ, Zhang Q, Song B, Jackson WS, Detloff PJ, Serra R, Yoder BK., Development 134(2), 2006
PMID: 17166921
Specification of neuronal fates in the ventral neural tube.
Briscoe J, Ericson J., Curr. Opin. Neurobiol. 11(1), 2001
PMID: 11179871
Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis.
Joksimovic M, Yun BA, Kittappa R, Anderegg AM, Chang WW, Taketo MM, McKay RD, Awatramani RB., Nat. Neurosci. 12(2), 2009
PMID: 19122665
IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport.
Keady BT, Samtani R, Tobita K, Tsuchya M, San Agustin JT, Follit JA, Jonassen JA, Subramanian R, Lo CW, Pazour GJ., Dev. Cell 22(5), 2012
PMID: 22595669
Genetic control of midbrain dopaminergic neuron development.
Blaess S, Ang SL., Wiley Interdiscip Rev Dev Biol 4(2), 2015
PMID: 25565353
Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei.
Blaess S, Bodea GO, Kabanova A, Chanet S, Mugniery E, Derouiche A, Stephen D, Joyner AL., Neural Dev 6(), 2011
PMID: 21689430
Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system.
Matise MP, Epstein DJ, Park HL, Platt KA, Joyner AL., Development 125(15), 1998
PMID: 9655799
Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors.
Liu A, Wang B, Niswander LA., Development 132(13), 2005
PMID: 15930098
Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons.
Tang M, Villaescusa JC, Luo SX, Guitarte C, Lei S, Miyamoto Y, Taketo MM, Arenas E, Huang EJ., J. Neurosci. 30(27), 2010
PMID: 20610763
Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel-Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and Wnt signalling defects.
Abdelhamed ZA, Wheway G, Szymanska K, Natarajan S, Toomes C, Inglehearn C, Johnson CA., Hum. Mol. Genet. 22(7), 2013
PMID: 23283079
Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development.
Deng Q, Andersson E, Hedlund E, Alekseenko Z, Coppola E, Panman L, Millonig JH, Brunet JF, Ericson J, Perlmann T., Development 138(16), 2011
PMID: 21752929
Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors.
Yan CH, Levesque M, Claxton S, Johnson RL, Ang SL., J. Neurosci. 31(35), 2011
PMID: 21880902
Genes, dopamine and cortical signal-to-noise ratio in schizophrenia.
Winterer G, Weinberger DR., Trends Neurosci. 27(11), 2004
PMID: 15474169
Identification of intrinsic determinants of midbrain dopamine neurons.
Andersson E, Tryggvason U, Deng Q, Friling S, Alekseenko Z, Robert B, Perlmann T, Ericson J., Cell 124(2), 2006
PMID: 16439212
Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord.
Lei Q, Zelman AK, Kuang E, Li S, Matise MP., Development 131(15), 2004
PMID: 15215207
The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking.
Liem KF Jr, Ashe A, He M, Satir P, Moran J, Beier D, Wicking C, Anderson KV., J. Cell Biol. 197(6), 2012
PMID: 22689656
Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development.
Yang J, Brown A, Ellisor D, Paul E, Hagan N, Zervas M., Development 140(6), 2013
PMID: 23444360
Hippi is essential for node cilia assembly and Sonic hedgehog signaling.
Houde C, Dickinson RJ, Houtzager VM, Cullum R, Montpetit R, Metzler M, Simpson EM, Roy S, Hayden MR, Hoodless PA, Nicholson DW., Dev. Biol. 300(2), 2006
PMID: 17027958
Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool.
Spassky N, Han YG, Aguilar A, Strehl L, Besse L, Laclef C, Ros MR, Garcia-Verdugo JM, Alvarez-Buylla A., Dev. Biol. 317(1), 2008
PMID: 18353302
Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells.
Andersson ER, Salto C, Villaescusa JC, Cajanek L, Yang S, Bryjova L, Nagy II, Vainio SJ, Ramirez C, Bryja V, Arenas E., Proc. Natl. Acad. Sci. U.S.A. 110(7), 2013
PMID: 23324743
Context-dependent regulation of Wnt signaling through the primary cilium.
Oh EC, Katsanis N., J. Am. Soc. Nephrol. 24(1), 2012
PMID: 23123400
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo.
Lai K, Kaspar BK, Gage FH, Schaffer DV., Nat. Neurosci. 6(1), 2003
PMID: 12469128
The Meckel-Gruber syndrome gene, MKS3, is mutated in Joubert syndrome.
Baala L, Romano S, Khaddour R, Saunier S, Smith UM, Audollent S, Ozilou C, Faivre L, Laurent N, Foliguet B, Munnich A, Lyonnet S, Salomon R, Encha-Razavi F, Gubler MC, Boddaert N, de Lonlay P, Johnson CA, Vekemans M, Antignac C, Attie-Bitach T., Am. J. Hum. Genet. 80(1), 2006
PMID: 17160906
Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches.
Machold R, Hayashi S, Rutlin M, Muzumdar MD, Nery S, Corbin JG, Gritli-Linde A, Dellovade T, Porter JA, Rubin LL, Dudek H, McMahon AP, Fishell G., Neuron 39(6), 2003
PMID: 12971894
The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation.
Corrales JD, Blaess S, Mahoney EM, Joyner AL., Development 133(9), 2006
PMID: 16571625
Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation.
Kimmel RA, Turnbull DH, Blanquet V, Wurst W, Loomis CA, Joyner AL., Genes Dev. 14(11), 2000
PMID: 10837030
Subcellular spatial regulation of canonical Wnt signalling at the primary cilium.
Lancaster MA, Schroth J, Gleeson JG., Nat. Cell Biol. 13(6), 2011
PMID: 21602792
THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia.
Tran PV, Haycraft CJ, Besschetnova TY, Turbe-Doan A, Stottmann RW, Herron BJ, Chesebro AL, Qiu H, Scherz PJ, Shah JV, Yoder BK, Beier DR., Nat. Genet. 40(4), 2008
PMID: 18327258
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