The maternal social environment shapes offspring growth, physiology, and behavioural phenotype in guinea pigs

von Engelhardt N, Kowalski GJ, Günther A (2015)
Frontiers in Zoology 12(Suppl 1): S13.

Download
OA 1.08 MB
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Volltext vorhanden für diesen Nachweis
Autor/in
Abstract / Bemerkung
Background Prenatal conditions influence offspring development in many species. In mammals, the effects of social density have traditionally been considered a detrimental form of maternal stress. Now their potential adaptive significance is receiving greater attention.Sex-specific effects of maternal social instability on offspring in guinea pigs (Cavia aperea f. porcellus) have been interpreted as adaptations to high social densities, while the effects of low social density are unknown. Hence, we compared morphological, behavioural and physiological development between offspring born to mothers housed either individually or in groups during the second half of pregnancy. Results Females housed individually and females housed in groups gave birth to litters of similar size and sex-ratios, and there were no differences in birth weight. Sons of individually-housed mothers grew faster than their sisters, whereas daughters ofgroup-housed females grew faster than their brothers, primarily due to an effect on growth of daughters. There were few effects on offspring behaviour. Baseline cortisol levels in saliva of pups on day 1 and day 7 were not affected, but we saw a blunted cortisol response to social separation on day 7 in sons of individually-housed females and daughters of group-housed females. The effects were consistent across two replicate experiments. Conclusions The observed effects only partially support the adaptive hypothesis. Increased growth of daughters may be adaptive under high densities due to increasedfemale competition, but it is unclear why growth of sons is not increased under low social densities when males face less competition from older, dominant males. The differences in growth may be causally linked to sex-specific effects on cortisol response, although individual cortisol response and growth were not correlated, and various other mechanisms are possible. The observed sex-specific effects on early development are intriguing, yet the potential adaptive benefits and physiological mechanisms require further study.
Erscheinungsjahr
Zeitschriftentitel
Frontiers in Zoology
Band
12
Ausgabe
Suppl 1
Art.-Nr.
S13
ISSN
Finanzierungs-Informationen
Article Processing Charge funded by the Deutsche Forschungsgemeinschaft and the Open Access Publication Fund of Bielefeld University.
PUB-ID

Zitieren

von Engelhardt N, Kowalski GJ, Günther A. The maternal social environment shapes offspring growth, physiology, and behavioural phenotype in guinea pigs. Frontiers in Zoology. 2015;12(Suppl 1): S13.
von Engelhardt, N., Kowalski, G. J., & Günther, A. (2015). The maternal social environment shapes offspring growth, physiology, and behavioural phenotype in guinea pigs. Frontiers in Zoology, 12(Suppl 1), S13. doi:10.1186/1742-9994-12-S1-S13
von Engelhardt, N., Kowalski, G. J., and Günther, A. (2015). The maternal social environment shapes offspring growth, physiology, and behavioural phenotype in guinea pigs. Frontiers in Zoology 12:S13.
von Engelhardt, N., Kowalski, G.J., & Günther, A., 2015. The maternal social environment shapes offspring growth, physiology, and behavioural phenotype in guinea pigs. Frontiers in Zoology, 12(Suppl 1): S13.
N. von Engelhardt, G.J. Kowalski, and A. Günther, “The maternal social environment shapes offspring growth, physiology, and behavioural phenotype in guinea pigs”, Frontiers in Zoology, vol. 12, 2015, : S13.
von Engelhardt, N., Kowalski, G.J., Günther, A.: The maternal social environment shapes offspring growth, physiology, and behavioural phenotype in guinea pigs. Frontiers in Zoology. 12, : S13 (2015).
von Engelhardt, Nikolaus, Kowalski, Gabriele J, and Günther, Anja. “The maternal social environment shapes offspring growth, physiology, and behavioural phenotype in guinea pigs”. Frontiers in Zoology 12.Suppl 1 (2015): S13.
Alle Dateien verfügbar unter der/den folgenden Lizenz(en):
Copyright Statement:
This Item is protected by copyright and/or related rights. [...]
Volltext(e)
Access Level
OA Open Access
Zuletzt Hochgeladen
2019-09-06T09:18:33Z

2 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Guinea pig models for translation of the developmental origins of health and disease hypothesis into the clinic.
Morrison JL, Botting KJ, Darby JRT, David AL, Dyson RM, Gatford KL, Gray C, Herrera EA, Hirst JJ, Kim B, Kind KL, Krause BJ, Matthews SG, Palliser HK, Regnault TRH, Richardson BS, Sasaki A, Thompson LP, Berry MJ., J Physiol 596(23), 2018
PMID: 29633280
Communal breeding affects offspring behaviours associated with a competitive social environment.
Fischer S, Pujol NT, Bolton R, Hurst JL, Stockley P., Sci Rep 8(1), 2018
PMID: 30443002

67 References

Daten bereitgestellt von Europe PubMed Central.

Fetal programming by maternal stress: Insights from a conflict perspective.
Del Giudice M., Psychoneuroendocrinology 37(10), 2012
PMID: 22694951
Adaptive modulation of behavioural profiles by social stress during early phases of life and adolescence.
Sachser N, Hennessy MB, Kaiser S., Neurosci Biobehav Rev 35(7), 2010
PMID: 20854842
Phenomena associated with population density.
CHRISTIAN JJ., Proc. Natl. Acad. Sci. U.S.A. 47(), 1961
PMID: 13693391
ENDOCRINES, BEHAVIOR, AND POPULATION.
CHRISTIAN JJ, DAVIS DE., Science 146(3651), 1964
PMID: 14224498
Developmental plasticity and human health.
Bateson P, Barker D, Clutton-Brock T, Deb D, D'Udine B, Foley RA, Gluckman P, Godfrey K, Kirkwood T, Lahr MM, McNamara J, Metcalfe NB, Monaghan P, Spencer HG, Sultan SE., Nature 430(6998), 2004
PMID: 15269759
Towards a new developmental synthesis: adaptive developmental plasticity and human disease.
Gluckman PD, Hanson MA, Bateson P, Beedle AS, Law CM, Bhutta ZA, Anokhin KV, Bougneres P, Chandak GR, Dasgupta P, Smith GD, Ellison PT, Forrester TE, Gilbert SF, Jablonka E, Kaplan H, Prentice AM, Simpson SJ, Uauy R, West-Eberhard MJ., Lancet 373(9675), 2009
PMID: 19427960
The effects of prenatal social stress on behaviour: mechanisms and function.
Kaiser S, Sachser N., Neurosci Biobehav Rev 29(2), 2005
PMID: 15811499
Adrenocortical and gonadal responses of female mice to increased population density.
CHRISTIAN JJ., Proc. Soc. Exp. Biol. Med. 104(), 1960
PMID: 13810124
Prenatal stress effects on exploratory activity and stress-induced analgesia in rats.
Szuran T, Zimmerman E, Pliska V, Pfister HP, Welzl H., Dev Psychobiol 24(5), 1991
PMID: 1752354
Effects of repeated stress during pregnancy in ewes on the behavioural and physiological responses to stressful events and birth weight of their offspring
AUTHOR UNKNOWN, 2004
Effects of prenatal stress on the fetal calf.
Lay DC Jr, Randel RD, Friend TH, Carroll JA, Welsh TH Jr, Jenkins OC, Neuendorff DA, Bushong DM, Kapp GM., Domest. Anim. Endocrinol. 14(2), 1997
PMID: 9063650
Density triggers maternal hormones that increase adaptive offspring growth in a wild mammal.
Dantzer B, Newman AE, Boonstra R, Palme R, Boutin S, Humphries MM, McAdam AG., Science 340(6137), 2013
PMID: 23599265
The effect of prenatal ”social stress” on anxiety
AUTHOR UNKNOWN, 2000
Effects of isolation on maternal aggressiveness and body growth rates of offspring.
Weltman AS, Sackler AM, Schwartz R, Stroman S., Experientia 23(9), 1967
PMID: 6070463
Postnatal behavioral and physiological responses of piglets from gilts housed individually or in groups during gestation.
Sorrells AD, Eicher SD, Scott KA, Harris MJ, Pajor EA, Lay DC Jr, Richert BT., J. Anim. Sci. 84(3), 2006
PMID: 16478968
Different forms of social organization at high and low population densities in guinea pigs
AUTHOR UNKNOWN, 1986
The puzzles of population cycles and outbreaks of small mammals solved?
AUTHOR UNKNOWN, 2004
Dynamic effects of predators on cyclic voles: field experimentation and model extrapolation.
Korpimaki E, Norrdahl K, Klemola T, Pettersen T, Stenseth NC., Proc. Biol. Sci. 269(1495), 2002
PMID: 12028754
Social system and spatial organization of wild guinea pigs (Cavia aperea) in a natural population
AUTHOR UNKNOWN, 2004
Living slow and dying young? Life-history strategy and age-specific survival rates in a precocial small mammal
AUTHOR UNKNOWN, 2005
Large males dominate: ecology, social organization, and mating system of wild cavies, the ancestors of the guinea pig
AUTHOR UNKNOWN, 2008
An unstable social environment affects sex ratio in guinea pigs: an adaptive maternal effect?
AUTHOR UNKNOWN, 2009
Sex-specific impact of prenatal stress on growth and reproductive parameters of guinea pigs.
Schopper H, Klaus T, Palme R, Ruf T, Huber S., J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. 182(8), 2012
PMID: 22714716
Prenatal glucocorticoid modifies hypothalamo-pituitary-adrenal regulation in prepubertal guinea pigs.
Dean F, Yu C, Lingas RI, Matthews SG., Neuroendocrinology 73(3), 2001
PMID: 11307038
Prenatal social stress masculinizes the females' behaviour in guinea pigs.
Sachser N, Kaiser S., Physiol. Behav. 60(2), 1996
PMID: 8840923
Prenatal stress does not impair coping with challenge later in life.
Kemme K, Kaiser S, Sachser N., Physiol. Behav. 93(1-2), 2007
PMID: 17727902
Prenatal social conditions shape offspring adult phenotype and reproductive success
AUTHOR UNKNOWN, 2014
Electroencephalographic blocking and adaptation.
DARROW CW, VIETH RN, WILSON J., Science 126(3263), 1957
PMID: 13442646
Prenatal psychological stress and offspring behavior in rats and mice.
Archer JE, Blackman DE., Dev Psychobiol 4(3), 1971
PMID: 4950118
Effects of prenatal stress on behaviour of offspring of laboratory and farmed mammals
AUTHOR UNKNOWN, 1998
Photoperiod influences the behavioral and physiological phenotype during ontogeny
AUTHOR UNKNOWN, 2013
The ontogeny of personality in the wild guinea pig
AUTHOR UNKNOWN, 2014
Dimensions of animal personalities in guinea pigs
AUTHOR UNKNOWN, 2013
Nongenomic transmission across generations of maternal behavior and stress responses in the rat.
Francis D, Diorio J, Liu D, Meaney MJ., Science 286(5442), 1999
PMID: 10550053
Effects of stress during pregnancy on maternal behavior in mice.
Meek LR, Dittel PL, Sheehan MC, Chan JY, Kjolhaug SR., Physiol. Behav. 72(4), 2001
PMID: 11282130
Cortisol responses and social buffering: a study throughout the life span.
Hennessy MB, Hornschuh G, Kaiser S, Sachser N., Horm Behav 49(3), 2005
PMID: 16242132
Effects of prenatal stress on fetal neurodevelopment and responses to maternal neurosteroid treatment in Guinea pigs.
Bennett GA, Palliser HK, Saxby B, Walker DW, Hirst JJ., Dev. Neurosci. 35(5), 2013
PMID: 24051896
Prenatal hormone exposure and sexual variation
AUTHOR UNKNOWN, 2003
The long-term behavioural consequences of prenatal stress.
Weinstock M., Neurosci Biobehav Rev 32(6), 2008
PMID: 18423592
Potential mechanisms for sex ratio adjustment in mammals and birds.
Krackow S., Biol Rev Camb Philos Soc 70(2), 1995
PMID: 7605846
Parental effects in ecology and evolution: mechanisms, processes and implications.
Badyaev AV, Uller T., Philos. Trans. R. Soc. Lond., B, Biol. Sci. 364(1520), 2009
PMID: 19324619
Prenatal stress and the programming of the HPA axis.
Glover V, O'Connor TG, O'Donnell K., Neurosci Biobehav Rev 35(1), 2009
PMID: 19914282
Effects of chronic stress during pregnancy on maternal performance in the guinea pig (Cavia aperea f. porcellus)
AUTHOR UNKNOWN, 2013
Puberty in female cavies (Cavia aperea) is affected by photoperiod and social conditions.
Trillmich F, Mueller B, Kaiser S, Krause J., Physiol. Behav. 96(3), 2008
PMID: 19087883
Characterization of new microsatellite loci for the South-American rodents Cavia aperea and C. magna
AUTHOR UNKNOWN, 2009
Mutualism between ecologists and ethologists?
Harcourt AH., Trends Ecol. Evol. (Amst.) 9(11), 1994
PMID: 21236921
Stability and change: stress responses and the shaping of behavioral phenotypes over the life span
AUTHOR UNKNOWN, 2015

AUTHOR UNKNOWN, 2011

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 26816513
PubMed | Europe PMC

Suchen in

Google Scholar