Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants
Danaei G, Fahimi S, Lu Y, Zhou B, Hajifathalian K, Di Cesare M, Lo W-C, Reis-Santos B, Cowan MJ, Shaw JE, Bentham J, et al. (2015)
The Lancet Diabetes & Endocrinology 3(8): 624-637.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Danaei, Goodarz;
Fahimi, Saman;
Lu, Yuan;
Zhou, Bin;
Hajifathalian, Kaveh;
Di Cesare, Mariachiara;
Lo, Wei-Cheng;
Reis-Santos, Barbara;
Cowan, Melanie J.;
Shaw, Jonathan E.;
Bentham, James;
Lin, John K.
Alle
Alle
Einrichtung
Abstract / Bemerkung
Background:
Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA(1c). We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabetes in a pooled analysis of data from population-based health examination surveys in different regions.
Methods:
We used data from 96 population-based health examination surveys that had measured at least two of the biomarkers used for defining diabetes. Diabetes was defined using HbA(1c) (HbA(1c) >= 6 . 5% or history of diabetes diagnosis or using insulin or oral hypoglycaemic drugs) compared with either FPG only or FPG-or-2hOGTT definitions (FPG >= 7 . 0 mmol/L or 2hOGTT >= 11 . 1 mmol/L or history of diabetes or using insulin or oral hypoglycaemic drugs). We calculated diabetes prevalence, taking into account complex survey design and survey sample weights. We compared the prevalences of diabetes using different definitions graphically and by regression analyses. We calculated sensitivity and specificity of diabetes diagnosis based on HbA1c compared with diagnosis based on glucose among previously undiagnosed individuals (ie, excluding those with history of diabetes or using insulin or oral hypoglycaemic drugs). We calculated sensitivity and specificity in each survey, and then pooled results using a random-effects model. We assessed the sources of heterogeneity of sensitivity by meta-regressions for study characteristics selected a priori.
Findings:
Population prevalence of diabetes based on FPG- or-2hOGTT was correlated with prevalence based on FPG alone (r= 0 . 98), but was higher by 2-6 percentage points at different prevalence levels. Prevalence based on HbA(1c) was lower than prevalence based on FPG in 42 . 8% of age-sex-survey groups and higher in another 41 . 6%; in the other 15 . 6%, the two definitions provided similar prevalence estimates. The variation across studies in the relation between glucose-based and HbA(1c)-based prevalences was partly related to participants' age, followed by natural logarithm of per person gross domestic product, the year of survey, mean BMI, and whether the survey population was national, subnational, or from specific communities. Diabetes defined as HbA(1c) 6 . 5% or more had a pooled sensitivity of 52 . 8% (95% CI 51 . 3-54 . 3%) and a pooled specificity of 99 . 74% (99 . 71-99 . 78%) compared with FPG 7 . 0 mmol/L or more for diagnosing previously undiagnosed participants; sensitivity compared with diabetes defined based on FPG-or-2hOGTT was 30 . 5% (28 . 7-32 . 3%). None of the preselected study-level characteristics explained the heterogeneity in the sensitivity of HbA(1c) versus FPG.
Interpretation:
Different biomarkers and definitions for diabetes can provide different estimates of population prevalence of diabetes, and differentially identify people without previous diagnosis as having diabetes. Using an HbA(1c)-based definition alone in health surveys will not identify a substantial proportion of previously undiagnosed people who would be considered as having diabetes using a glucose-based test.
Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA(1c). We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabetes in a pooled analysis of data from population-based health examination surveys in different regions.
Methods:
We used data from 96 population-based health examination surveys that had measured at least two of the biomarkers used for defining diabetes. Diabetes was defined using HbA(1c) (HbA(1c) >= 6 . 5% or history of diabetes diagnosis or using insulin or oral hypoglycaemic drugs) compared with either FPG only or FPG-or-2hOGTT definitions (FPG >= 7 . 0 mmol/L or 2hOGTT >= 11 . 1 mmol/L or history of diabetes or using insulin or oral hypoglycaemic drugs). We calculated diabetes prevalence, taking into account complex survey design and survey sample weights. We compared the prevalences of diabetes using different definitions graphically and by regression analyses. We calculated sensitivity and specificity of diabetes diagnosis based on HbA1c compared with diagnosis based on glucose among previously undiagnosed individuals (ie, excluding those with history of diabetes or using insulin or oral hypoglycaemic drugs). We calculated sensitivity and specificity in each survey, and then pooled results using a random-effects model. We assessed the sources of heterogeneity of sensitivity by meta-regressions for study characteristics selected a priori.
Findings:
Population prevalence of diabetes based on FPG- or-2hOGTT was correlated with prevalence based on FPG alone (r= 0 . 98), but was higher by 2-6 percentage points at different prevalence levels. Prevalence based on HbA(1c) was lower than prevalence based on FPG in 42 . 8% of age-sex-survey groups and higher in another 41 . 6%; in the other 15 . 6%, the two definitions provided similar prevalence estimates. The variation across studies in the relation between glucose-based and HbA(1c)-based prevalences was partly related to participants' age, followed by natural logarithm of per person gross domestic product, the year of survey, mean BMI, and whether the survey population was national, subnational, or from specific communities. Diabetes defined as HbA(1c) 6 . 5% or more had a pooled sensitivity of 52 . 8% (95% CI 51 . 3-54 . 3%) and a pooled specificity of 99 . 74% (99 . 71-99 . 78%) compared with FPG 7 . 0 mmol/L or more for diagnosing previously undiagnosed participants; sensitivity compared with diabetes defined based on FPG-or-2hOGTT was 30 . 5% (28 . 7-32 . 3%). None of the preselected study-level characteristics explained the heterogeneity in the sensitivity of HbA(1c) versus FPG.
Interpretation:
Different biomarkers and definitions for diabetes can provide different estimates of population prevalence of diabetes, and differentially identify people without previous diagnosis as having diabetes. Using an HbA(1c)-based definition alone in health surveys will not identify a substantial proportion of previously undiagnosed people who would be considered as having diabetes using a glucose-based test.
Erscheinungsjahr
2015
Zeitschriftentitel
The Lancet Diabetes & Endocrinology
Band
3
Ausgabe
8
Seite(n)
624-637
Urheberrecht / Lizenzen
ISSN
2213-8587
Page URI
https://pub.uni-bielefeld.de/record/2772521
Zitieren
Danaei G, Fahimi S, Lu Y, et al. Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants. The Lancet Diabetes & Endocrinology. 2015;3(8):624-637.
Danaei, G., Fahimi, S., Lu, Y., Zhou, B., Hajifathalian, K., Di Cesare, M., Lo, W. - C., et al. (2015). Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants. The Lancet Diabetes & Endocrinology, 3(8), 624-637. doi:10.1016/S2213-8587(15)00129-1
Danaei, Goodarz, Fahimi, Saman, Lu, Yuan, Zhou, Bin, Hajifathalian, Kaveh, Di Cesare, Mariachiara, Lo, Wei-Cheng, et al. 2015. “Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants”. The Lancet Diabetes & Endocrinology 3 (8): 624-637.
Danaei, G., Fahimi, S., Lu, Y., Zhou, B., Hajifathalian, K., Di Cesare, M., Lo, W. - C., Reis-Santos, B., Cowan, M. J., Shaw, J. E., et al. (2015). Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants. The Lancet Diabetes & Endocrinology 3, 624-637.
Danaei, G., et al., 2015. Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants. The Lancet Diabetes & Endocrinology, 3(8), p 624-637.
G. Danaei, et al., “Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants”, The Lancet Diabetes & Endocrinology, vol. 3, 2015, pp. 624-637.
Danaei, G., Fahimi, S., Lu, Y., Zhou, B., Hajifathalian, K., Di Cesare, M., Lo, W.-C., Reis-Santos, B., Cowan, M.J., Shaw, J.E., Bentham, J., Lin, J.K., Bixby, H., Magliano, D., Bovet, P., Miranda, J.J., Khang, Y.-H., Stevens, G.A., Riley, L.M., Ali, M.K., Ezzati, M., Abdeen, Z.A., Kadir, K.A., Abu-Rmeileh, N.M., Acosta-Cazares, B., Aekplakorn, W., Aguilar-Salinas, C.A., Ahmadvand, A., Al Nsour, M., Alkerwi, A.'a, Amouyel, P., Andersen, L.B., Anderssen, S.A., Andrade, D.S., Anjana, R.M., Aounallah-Skhiri, H., Aris, T., Arlappa, N., Arveiler, D., Assah, F.K., Avdicova, M., Balakrishna, N., Bandosz, P., Barbagallo, C.M., Barcelo, A., Batieha, A.M., Baur, L.A., Ben Romdhane, H., Bernabe-Ortiz, A., Bhargava, S.K., Bi, Y., Bjerregaard, P., Bjorkelund, C., Blake, M., Blokstra, A., Bo, S., Boehm, B.O., Boissonnet, C.P., Bovet, P., Brajkovich, I., Breckenkamp, J., Brewster, L.M., Brian, G.R., Bruno, G., Bugge, A., de Leon, A.C., Can, G., Candido, A.P.C., Capuano, V., Carvalho, M.J., Casanueva, F.F., Caserta, C.A., Castetbon, K., Chamukuttan, S., Chaturvedi, N., Chen, C.-J., Chen, F., Chen, S., Cheng, C.-Y., Chetrit, A., Chiou, S.-T., Cho, Y., Chudek, J., Cifkova, R., Claessens, F., Concin, H., Cooper, C., Cooper, R., Costanzo, S., Cottel, D., Cowell, C., Crujeiras, A.B., D'Arrigo, G., Dallongeville, J., Dankner, R., Dauchet, L., de Gaetano, G., De Henauw, S., Deepa, M., Dehghan, A., Dhana, K., Di Castelnuovo, A.F., Djalalinia, S., Doua, K., Drygas, W., Du, Y., Egbagbe, E.E., Eggertsen, R., El Ati, J., Elosua, R., Erasmus, R.T., Erem, C., Ergor, G., Eriksen, L., la Penaa, J.E.-D., Fall, C.H., Farzadfar, F., Felix-Redondo, F.J., Ferguson, T.S., Fernandez-Berges, D., Ferrari, M., Ferreccio, C., Finn, J.D., Foger, B., Foo, L.H., Fouad, H.M., Francis, D.K., Franco, M. do C., Franco, O.H., Frontera, G., Furusawa, T., Gaciong, Z., Galbarczyk, A., Garnett, S.P., Gaspoz, J.-M., Gasull, M., Gates, L., Geleijnse, J.M., Ghasemain, A., Giampaoli, S., Gianfagna, F., Giovannelli, J., Gross, M.G., Rivas, J.P.G., Gorbea, M.B., Gottrand, F., Grant, J.F., Grodzicki, T., Grontved, A., Gruden, G., Gu, D., Guan, O.P., Guerrero, R., Guessous, I., Guimaraes, A.L., Gutierrez, L., Hardy, R., Kumar, R.H., He, J., Heidemann, C., Hihtaniemi, I.T., Ho, S.Y., Ho, S.C., Hofman, A., Russo, A.R.V., Hormiga, C.M., Horta, B.L., Houti, L., Hussieni, A.S., Huybrechts, I., Hwalla, N., Iacoviello, L., Iannone, A.G., Ibrahim, M.M., Ikeda, N., Ikram, M.A., Irazola, V.E., Islam, M., Iwasaki, M., Jacobs, J.M., Jafar, T., Jasienska, G., Jiang, C.Q., Jonas, J.B., Joshi, P., Kafatos, A., Kalter-Leibovici, O., Kasaeian, A., Katz, J., Kaur, P., Kavousi, M., Kelishadi, R., Kengne, A.P., Kersting, M., Khader, Y.S., Khang, Y.-H., Kiechl, S., Kim, J., Kiyohara, Y., Kolsteren, P., Korrovits, P., Koskinen, S., Kratzer, W., Kromhout, D., Kula, K., Kurjata, P., Kyobutungi, C., Lachat, C., Laid, Y., Lam, T.H., Landrove, O., Lanska, V., Lappas, G., Laxmaiah, A., Leclercq, C., Lee, J., Lee, J., Lehtimaki, T., Lekhraj, R., Leon-Munoz, L.M., Li, Y., Lim, W.-Y., Lima-Costa, M.F., Lin, H.-H., Lin, X., Lissner, L., Lorbeer, R., Lozano, J.E., Lundqvist, A., Lytsy, P., Ma, G., Machado-Coelho, G.L.L., Machi, S., Maggi, S., Magliano, D., Makdisse, M., Rao, K.M., Manios, Y., Manzato, E., Margozzini, P., Marques-Vidal, P., Martorell, R., Masoodi, S.R., Matsha, T.E., Mbanya, J.C.N., McFarlane, S.R., McGarvey, S.T., McLachlan, S., McNulty, B.A., Mediene-Benchekor, S., Meirhaeghe, A., Menezes, A.M.B., Merat, S., Meshram, I.I., Mi, J., Miquel, J.F., Miranda, J.J., Mohamed, M.K., Mohammad, K., Mohan, V., Yusoff, M.F.M., Moller, N.C., Molnar, D., Mondo, C.K., Moreno, L.A., Morgan, K., Moschonis, G., Mossakowska, M., Mostafa, A., Mota, J., Muiesan, M.L., Muller-Nurasyid, M., Mursu, J., Nagel, G., Namesna, J., Nang, E.E.K., Nangia, V.B., Navarrete-Munoz, E.M., Ndiaye, N.C., Nervi, F., Nguyen, N.D., Nieto-Martinez, R.S.E., Ning, G., Ninomiya, T., Noale, M., Noto, D., Ochoa-Aviles, A.M., Oh, K., Onat, A., Osmond, C., Otero, J.A., Palmieri, L., Panda-Jonas, S., Panza, F., Parsaeian, M., Peixoto, S.V., Pereira, A.C., Peters, A., Peykari, N., Pilav, A., Pitakaka, F., Piwonska, A., Piwonski, J., Plans-Rubio, P., Porta, M., Portegies, M.L.P., Poustchi, H., Pradeepa, R., Price, J.F., Punab, M., Qasrawi, R.F., Qorbani, M., Raitakari, O., Rao, S.R., Ramachandran, A., Ramos, R., Rampal, S., Rathmann, W., Redon, J., Reganit, P.F.M., Rigo, F., Robinson, S.M., Robitaille, C., Rodriguez, L.A., Rodriguez-Artalejo, F., Rodriguez-Perez, M. del C., Rojas-Martinez, R., Romaguera, D., Rosengren, A., Rubinstein, A., Rui, O., Ruiz-Betancourt, B.S., Rutkowski, M., Sabanayagam, C., Sachdev, H.S., Saidi, O., Sakarya, S., Salanave, B., Salonen, J.T., Salvetti, M., Sanchez-Abanto, J., Nunes, R., Santos, R., Sardinha, L.B., Scazufca, M., Schargrodsky, H., Scheidt-Nave, C., Shaw, J.E., Shibuya, K., Shin, Y., Shiri, R., Siantar, R., Sibai, A.M., Simon, M., Simons, J., Simons, L.A., Sjostrom, M., Slowikowska-Hilczer, J., Slusarczyk, P., Smeeth, L., Snijder, M.B., Solfrizzi, V., Sonestedt, E., Soumare, A., Staessen, J.A., Steene-Johannessen, J., Stehle, P., Stein, A.D., Stessman, J., Stockl, D., Stokwiszewski, J., Strufaldi, M.W., Sun, C.-A., Sundstrom, J., Suriyawongpaisal, P., Sy, R.G., Tai, E.S., Tarawneh, M., Tarqui-Mamani, C.B., Thijs, L., Tolstrup, J.S., Topbas, M., Torrent, M., Traissac, P., Trinh, O.T.H., Tulloch-Reid, M.K., Tuomainen, T.-P., Turley, M.L., Tzourio, C., Ueda, P., Ukoli, F.M., Ulmer, H., Valdivia, G., Van Valkengoed, I.G.M., Vanderschueren, D., Vanuzzo, D., Vega, T., Velasquez-Melendez, G., Veronesi, G., Verschuren, M., Vioque, J., Virtanen, J., Visvikis-Siest, S., Viswanathan, B., Vollenweider, P., Voutilainen, S., Wade, A.N., Wagner, A., Walton, J., Mohamud, W.N.W., Wang, M.-D., Wang, Y.X., Wannamethee, S.G., Weerasekera, D., Whincup, P.H., Widhalm, K., Wiecek, A., Wilks, R.J., Willeit, J., Wojtyniak, B., Wong, T.Y., Woo, J., Woodward, M., Wu, A.G., Wu, F.C., Wu, S.L., Xu, H., Yang, X., Ye, X., Yoshihara, A., Younger-Coleman, N.O., Zambon, S., Zargar, A.H., Zdrojewski, T., Zhao, W., Zheng, Y.: Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants. The Lancet Diabetes & Endocrinology. 3, 624-637 (2015).
Danaei, Goodarz, Fahimi, Saman, Lu, Yuan, Zhou, Bin, Hajifathalian, Kaveh, Di Cesare, Mariachiara, Lo, Wei-Cheng, Reis-Santos, Barbara, Cowan, Melanie J., Shaw, Jonathan E., Bentham, James, Lin, John K., Bixby, Honor, Magliano, Dianna, Bovet, Pascal, Miranda, J. Jaime, Khang, Young-Ho, Stevens, Gretchen A., Riley, Leanne M., Ali, Mohammed K., Ezzati, Majid, Abdeen, Ziad A., Kadir, Khalid Abdul, Abu-Rmeileh, Niveen M., Acosta-Cazares, Benjamin, Aekplakorn, Wichai, Aguilar-Salinas, Carlos A., Ahmadvand, Alireza, Al Nsour, Mohannad, Alkerwi, Ala'a, Amouyel, Philippe, Andersen, Lars Bo, Anderssen, Sigmund A., Andrade, Dolores S., Anjana, Ranjit Mohan, Aounallah-Skhiri, Hajer, Aris, Tahir, Arlappa, Nimmathota, Arveiler, Dominique, Assah, Felix K., Avdicova, Maria, Balakrishna, Nagalla, Bandosz, Piotr, Barbagallo, Carlo M., Barcelo, Alberto, Batieha, Anwar M., Baur, Louise A., Ben Romdhane, Habiba, Bernabe-Ortiz, Antonio, Bhargava, Santosh K., Bi, Yufang, Bjerregaard, Peter, Bjorkelund, Cecilia, Blake, Margaret, Blokstra, Anneke, Bo, Simona, Boehm, Bernhard O., Boissonnet, Carlos P., Bovet, Pascal, Brajkovich, Imperia, Breckenkamp, Jürgen, Brewster, Lizzy M., Brian, Garry R., Bruno, Graziella, Bugge, Anna, de Leon, Antonio Cabrera, Can, Gunay, Candido, Ana Paula C., Capuano, Vincenzo, Carvalho, Maria J., Casanueva, Felipe F., Caserta, Carmelo A., Castetbon, Katia, Chamukuttan, Snehalatha, Chaturvedi, Nishi, Chen, Chien-Jen, Chen, Fangfang, Chen, Shuohua, Cheng, Ching-Yu, Chetrit, Angela, Chiou, Shu-Ti, Cho, Yumi, Chudek, Jerzy, Cifkova, Renata, Claessens, Frank, Concin, Hans, Cooper, Cyrus, Cooper, Rachel, Costanzo, Simona, Cottel, Dominique, Cowell, Chris, Crujeiras, Ana B., D'Arrigo, Graziella, Dallongeville, Jean, Dankner, Rachel, Dauchet, Luc, de Gaetano, Giovanni, De Henauw, Stefaan, Deepa, Mohan, Dehghan, Abbas, Dhana, Klodian, Di Castelnuovo, Augusto F., Djalalinia, Shirin, Doua, Kouamelan, Drygas, Wojciech, Du, Yong, Egbagbe, Eruke E., Eggertsen, Robert, El Ati, Jalila, Elosua, Roberto, Erasmus, Rajiv T., Erem, Cihangir, Ergor, Gul, Eriksen, Louise, la Penaa, Jorge Escobedo-De, Fall, Caroline H., Farzadfar, Farshad, Felix-Redondo, Francisco J., Ferguson, Trevor S., Fernandez-Berges, Daniel, Ferrari, Marika, Ferreccio, Catterina, Finn, Joseph D., Foger, Bernhard, Foo, Leng Huat, Fouad, Heba M., Francis, Damian K., Franco, Maria do Carmo, Franco, Oscar H., Frontera, Guillermo, Furusawa, Takuro, Gaciong, Zbigniew, Galbarczyk, Andrzej, Garnett, Sarah P., Gaspoz, Jean-Michel, Gasull, Magda, Gates, Louise, Geleijnse, Johanna M., Ghasemain, Anoosheh, Giampaoli, Simona, Gianfagna, Francesco, Giovannelli, Jonathan, Gross, Marcela Gonzalez, Rivas, Juan P. Gonzalez, Gorbea, Mariano Bonet, Gottrand, Frederic, Grant, Janet F., Grodzicki, Tomasz, Grontved, Anders, Gruden, Grabriella, Gu, Dongfeng, Guan, Ong Peng, Guerrero, Ramiro, Guessous, Idris, Guimaraes, Andre L., Gutierrez, Laura, Hardy, Rebecca, Kumar, Rachakulla Hari, He, Jiang, Heidemann, Christin, Hihtaniemi, Ilpo Tapani, Ho, Sai Yin, Ho, Suzanne C., Hofman, Albert, Russo, Andrea R. V., Hormiga, Claudia M., Horta, Bernardo L., Houti, Leila, Hussieni, Abdullatif S., Huybrechts, Inge, Hwalla, Nahla, Iacoviello, Licia, Iannone, Anna G., Ibrahim, Mohsen M., Ikeda, Nayu, Ikram, M. Arfan, Irazola, Vilma E., Islam, Muhammad, Iwasaki, Masanori, Jacobs, Jeremy M., Jafar, Tazeen, Jasienska, Grazyna, Jiang, Chao Qiang, Jonas, Jost B., Joshi, Pradeep, Kafatos, Anthony, Kalter-Leibovici, Ofra, Kasaeian, Amir, Katz, Joanne, Kaur, Prabhdeep, Kavousi, Maryam, Kelishadi, Roya, Kengne, Andre P., Kersting, Mathilde, Khader, Yousef Saleh, Khang, Young-Ho, Kiechl, Stefan, Kim, Jeongseon, Kiyohara, Yutaka, Kolsteren, Patrick, Korrovits, Paul, Koskinen, Seppo, Kratzer, Wolfgang, Kromhout, Daan, Kula, Krzysztof, Kurjata, Pawel, Kyobutungi, Catherine, Lachat, Carl, Laid, Youcef, Lam, Tai Hing, Landrove, Orlando, Lanska, Vera, Lappas, Georg, Laxmaiah, Avula, Leclercq, Catherine, Lee, Jeannette, Lee, Jeonghee, Lehtimaki, Terho, Lekhraj, Rampal, Leon-Munoz, Luz M., Li, Yanping, Lim, Wei-Yen, Lima-Costa, M. Fernanda, Lin, Hsien-Ho, Lin, Xu, Lissner, Lauren, Lorbeer, Roberto, Lozano, Jose Eugenio, Lundqvist, Annamari, Lytsy, Per, Ma, Guansheng, Machado-Coelho, George L. L., Machi, Suka, Maggi, Stefania, Magliano, Dianna, Makdisse, Marcia, Rao, Kodavanti Mallikharjuna, Manios, Yannis, Manzato, Enzo, Margozzini, Paula, Marques-Vidal, Pedro, Martorell, Reynaldo, Masoodi, Shariq R., Matsha, Tandi E., Mbanya, Jean Claude N., McFarlane, Shelly R., McGarvey, Stephen T., McLachlan, Stela, McNulty, Breige A., Mediene-Benchekor, Sounnia, Meirhaeghe, Aline, Menezes, Ana Maria B., Merat, Shahin, Meshram, Indrapal I., Mi, Jie, Miquel, Juan Francisco, Miranda, J. Jaime, Mohamed, Mostafa K., Mohammad, Kazem, Mohan, Viswanathan, Yusoff, Muhammad Fadhli Mohd, Moller, Niels C., Molnar, Denes, Mondo, Charles K., Moreno, Luis A., Morgan, Karen, Moschonis, George, Mossakowska, Malgorzata, Mostafa, Aya, Mota, Jorge, Muiesan, Maria L., Muller-Nurasyid, Martina, Mursu, Jaakko, Nagel, Gabriele, Namesna, Jana, Nang, Ei Ei K., Nangia, Vinay B., Navarrete-Munoz, Eva Maria, Ndiaye, Ndeye Coumba, Nervi, Flavio, Nguyen, Nguyen D., Nieto-Martinez, Ramfi S. E., Ning, Guang, Ninomiya, Toshiharu, Noale, Marianna, Noto, Davide, Ochoa-Aviles, Angelica M., Oh, Kyungwon, Onat, Altan, Osmond, Clive, Otero, Johanna A., Palmieri, Luigi, Panda-Jonas, Songhomitra, Panza, Francesco, Parsaeian, Mahboubeh, Peixoto, Sergio Viana, Pereira, Alexandre C., Peters, Annette, Peykari, Niloofar, Pilav, Aida, Pitakaka, Freda, Piwonska, Aleksandra, Piwonski, Jerzy, Plans-Rubio, Pedro, Porta, Miquel, Portegies, Marileen L. P., Poustchi, Hossein, Pradeepa, Rajendra, Price, Jacqueline F., Punab, Margus, Qasrawi, Radwan F., Qorbani, Mostafa, Raitakari, Olli, Rao, Sudha Ramachandra, Ramachandran, Ambady, Ramos, Rafel, Rampal, Sanjay, Rathmann, Wolfgang, Redon, Josep, Reganit, Paul Ferdinand M., Rigo, Fernando, Robinson, Sian M., Robitaille, Cynthia, Rodriguez, Laura A., Rodriguez-Artalejo, Fernando, Rodriguez-Perez, Maria del Cristo, Rojas-Martinez, Rosalba, Romaguera, Dora, Rosengren, Annika, Rubinstein, Adolfo, Rui, Ornelas, Ruiz-Betancourt, Blanca Sandra, Rutkowski, Marcin, Sabanayagam, Charumathi, Sachdev, Harshpal S., Saidi, Olfa, Sakarya, Sibel, Salanave, Benoit, Salonen, Jukka T., Salvetti, Massimo, Sanchez-Abanto, Jose, Nunes, Renata, Santos, Rute, Sardinha, Luis B., Scazufca, Marcia, Schargrodsky, Herman, Scheidt-Nave, Christa, Shaw, Jonathan E., Shibuya, Kenji, Shin, Youchan, Shiri, Rahman, Siantar, Rosalynn, Sibai, Abla M., Simon, Mary, Simons, Judith, Simons, Leon A., Sjostrom, Michael, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemyslaw, Smeeth, Liam, Snijder, Marieke B., Solfrizzi, Vincenzo, Sonestedt, Emily, Soumare, Aicha, Staessen, Jan A., Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D., Stessman, Jochanan, Stockl, Doris, Stokwiszewski, Jakub, Strufaldi, Maria Wany, Sun, Chien-An, Sundstrom, Johan, Suriyawongpaisal, Paibul, Sy, Rody G., Tai, E. Shyong, Tarawneh, Mohammed, Tarqui-Mamani, Carolina B., Thijs, Lutgarde, Tolstrup, Janne S., Topbas, Murat, Torrent, Maties, Traissac, Pierre, Trinh, Oanh T. H., Tulloch-Reid, Marshall K., Tuomainen, Tomi-Pekka, Turley, Maria L., Tzourio, Christophe, Ueda, Peter, Ukoli, Flora M., Ulmer, Hanno, Valdivia, Gonzalo, Van Valkengoed, Irene G. M., Vanderschueren, Dirk, Vanuzzo, Diego, Vega, Tomas, Velasquez-Melendez, Gustavo, Veronesi, Giovanni, Verschuren, Monique, Vioque, Jesus, Virtanen, Jyrki, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vollenweider, Peter, Voutilainen, Sari, Wade, Alisha N., Wagner, Aline, Walton, Janette, Mohamud, Wan Nazaimoon Wan, Wang, Ming-Dong, Wang, Ya Xing, Wannamethee, S. Goya, Weerasekera, Deepa, Whincup, Peter H., Widhalm, Kurt, Wiecek, Andrzej, Wilks, Rainford J., Willeit, Johann, Wojtyniak, Bogdan, Wong, Tien Yin, Woo, Jean, Woodward, Mark, Wu, Aleksander Giwercman, Wu, Frederick C., Wu, Shou Ling, Xu, Haiquan, Yang, Xiaoguang, Ye, Xingwang, Yoshihara, Akihiro, Younger-Coleman, Novie O., Zambon, Sabina, Zargar, Abdul Hamid, Zdrojewski, Tomasz, Zhao, Wenhua, and Zheng, Yingfeng. “Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants”. The Lancet Diabetes & Endocrinology 3.8 (2015): 624-637.
Export
Markieren/ Markierung löschen
Markierte Publikationen
Web of Science
Dieser Datensatz im Web of Science®Quellen
PMID: 26109024
PubMed | Europe PMC
Suchen in
Google Scholar