A new xanthone derivative from twigs of Garcinia nobilis

Fouotsa H, Tatsimo SJN, Neumann B, Michalek C, Mbazoa CD, Nkengfack AE, Sewald N, Lannang AM (2014)
Natural Product Research 28(14): 1030-1036.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Fouotsa, HuguesUniBi; Tatsimo, Simplice J. N.; Neumann, BeateUniBi; Michalek, CarmelaUniBi; Mbazoa, Celine Djama; Nkengfack, Augustin Ephrem; Sewald, NorbertUniBi ; Lannang, Alain MeliUniBi
Abstract / Bemerkung
Phytochemical investigation of the twigs of Garcinia nobilis led to the isolation of a new xanthone, named l-hydroxy-2,5-dimethoxyxanthone (1), together with 15 known compounds (2-16). The structures of the new and known compounds were established by means of spectroscopic methods and by comparison with previously reported data. The structure of compound 1 was confirmed by X-ray diffraction data. Compounds 1-16 were tested for their cytotoxic activity against human cervix carcinoma cell line KB-3-1. Compounds 5 and 11 showed moderate activity while others showed weak biological activity in these cytotoxicity assays. Compounds 4 and 9 were found to be inactive.
Stichworte
cytotoxicity; Guttiferae; xanthone; Garcinia nobilis
Erscheinungsjahr
2014
Zeitschriftentitel
Natural Product Research
Band
28
Ausgabe
14
Seite(n)
1030-1036
ISSN
1478-6419
eISSN
1478-6427
Page URI
https://pub.uni-bielefeld.de/record/2690949

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Fouotsa H, Tatsimo SJN, Neumann B, et al. A new xanthone derivative from twigs of Garcinia nobilis. Natural Product Research. 2014;28(14):1030-1036.
Fouotsa, H., Tatsimo, S. J. N., Neumann, B., Michalek, C., Mbazoa, C. D., Nkengfack, A. E., Sewald, N., et al. (2014). A new xanthone derivative from twigs of Garcinia nobilis. Natural Product Research, 28(14), 1030-1036. doi:10.1080/14786419.2014.903398
Fouotsa, Hugues, Tatsimo, Simplice J. N., Neumann, Beate, Michalek, Carmela, Mbazoa, Celine Djama, Nkengfack, Augustin Ephrem, Sewald, Norbert, and Lannang, Alain Meli. 2014. “A new xanthone derivative from twigs of Garcinia nobilis”. Natural Product Research 28 (14): 1030-1036.
Fouotsa, H., Tatsimo, S. J. N., Neumann, B., Michalek, C., Mbazoa, C. D., Nkengfack, A. E., Sewald, N., and Lannang, A. M. (2014). A new xanthone derivative from twigs of Garcinia nobilis. Natural Product Research 28, 1030-1036.
Fouotsa, H., et al., 2014. A new xanthone derivative from twigs of Garcinia nobilis. Natural Product Research, 28(14), p 1030-1036.
H. Fouotsa, et al., “A new xanthone derivative from twigs of Garcinia nobilis”, Natural Product Research, vol. 28, 2014, pp. 1030-1036.
Fouotsa, H., Tatsimo, S.J.N., Neumann, B., Michalek, C., Mbazoa, C.D., Nkengfack, A.E., Sewald, N., Lannang, A.M.: A new xanthone derivative from twigs of Garcinia nobilis. Natural Product Research. 28, 1030-1036 (2014).
Fouotsa, Hugues, Tatsimo, Simplice J. N., Neumann, Beate, Michalek, Carmela, Mbazoa, Celine Djama, Nkengfack, Augustin Ephrem, Sewald, Norbert, and Lannang, Alain Meli. “A new xanthone derivative from twigs of Garcinia nobilis”. Natural Product Research 28.14 (2014): 1030-1036.

7 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Secondary metabolites from Aspergillus japonicus CAM231, an endophytic fungus associated with Garcinia preussii.
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