Cognitive and Surgical Outcome in Mesial Temporal Lobe Epilepsy Associated with Hippocampal Sclerosis Plus Neurocysticercosis: A Cohort Study

Bianchin MM, Velasco TR, Coimbra ER, Gargaro AC, Escorsi-Rosset SR, Wichert-Ana L, Terra VC, Alexandre V, J, Araujo D, J, dos Santos AC, Fernandes RMF, et al. (2013)
Plos One 8(4): e60949.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Bianchin, Marino M.; Velasco, Tonicarlo R.; Coimbra, Erica R.; Gargaro, Ana C.; Escorsi-Rosset, Sara R.; Wichert-Ana, Lauro; Terra, Vera C.; Alexandre, Veriano, Jr.; Araujo, David, Jr.; dos Santos, Antonio Carlos; Fernandes, Regina M. F.; Assirati, Joao A., Jr.
Alle
Abstract / Bemerkung
Background: Where neurocysticercosis (NCC) is endemic, chronic calcified neurocysticercosis (cNCC) can be observed in patients with mesial temporal lobe epilepsy associated with hippocampal sclerosis (MTLE-HS). Considering that both disorders cause recurrent seizures or cognitive impairment, we evaluated if temporal lobectomy is cognitively safe and effective for seizure control in MTLE-HS plus cNCC. Methods: Retrospective cohort study of neuropsychological profile and surgical outcome of 324 MTLE-HS patients submitted to temporal lobectomy, comparing the results according to the presence or absence of cNCC. Findings: cNCC occurred in 126 (38.9%) of our MTLE-HS patients, a frequency higher than expected, more frequently in women than in men (O.R. = 1.66; 95% C. I. = 1.05-2.61; p = 0.03). Left-side (but not right side) surgery caused impairment in selected neuropsychological tests, but this impairment was not accentuated by the presence of cNCC. Ninety-four (74.6%) patients with MTLE-HS plus cNCC and 153 patients (77.3%) with MTLE-HS alone were Engel class I after surgery (O.R. = 1.16; 95% C. I. = 0.69-1.95; p = 0.58). However, the chances of Engel class IA were significantly lower in MTLE-HS plus cNCC than in patients with MTLE-HS alone (31.7% versus 48.5%; O.R. = 2.02; 95% C. I. = 1.27-3.23; p = 0.003). Patients with MTLE-HS plus cNCC showed higher rates of Engel class ID (15.1% versus 6.6%; O.R. = 2.50; 95% C. I. = 1.20-5.32; p = 0.012). Interpretation: cNCC can be highly prevalent among MTLE-HS patients living in areas where neurocysticercosis is endemic, suggesting a cause-effect relationship between the two diseases. cNCC does not add further risk for cognitive decline after surgery in MTLE-HS patients. The rates of Engel class I outcome were very similar for the two groups; however, MTLE-HS plus cNCC patients achieved Engel IA status less frequently, and Engel ID status more frequently. Temporal lobectomy can be safely performed in most patients with MTLE-HS plus cNCC without affecting cognitive outcome. Long-term surgical seizure control in MTLE-HS plus cNCC is still satisfactory, as long as selected patients remain under medication.
Erscheinungsjahr
2013
Zeitschriftentitel
Plos One
Band
8
Ausgabe
4
Art.-Nr.
e60949
ISSN
1932-6203
eISSN
1932-6203
Page URI
https://pub.uni-bielefeld.de/record/2607302

Zitieren

Bianchin MM, Velasco TR, Coimbra ER, et al. Cognitive and Surgical Outcome in Mesial Temporal Lobe Epilepsy Associated with Hippocampal Sclerosis Plus Neurocysticercosis: A Cohort Study. Plos One. 2013;8(4): e60949.
Bianchin, M. M., Velasco, T. R., Coimbra, E. R., Gargaro, A. C., Escorsi-Rosset, S. R., Wichert-Ana, L., Terra, V. C., et al. (2013). Cognitive and Surgical Outcome in Mesial Temporal Lobe Epilepsy Associated with Hippocampal Sclerosis Plus Neurocysticercosis: A Cohort Study. Plos One, 8(4), e60949. doi:10.1371/journal.pone.0060949
Bianchin, Marino M., Velasco, Tonicarlo R., Coimbra, Erica R., Gargaro, Ana C., Escorsi-Rosset, Sara R., Wichert-Ana, Lauro, Terra, Vera C., et al. 2013. “Cognitive and Surgical Outcome in Mesial Temporal Lobe Epilepsy Associated with Hippocampal Sclerosis Plus Neurocysticercosis: A Cohort Study”. Plos One 8 (4): e60949.
Bianchin, M. M., Velasco, T. R., Coimbra, E. R., Gargaro, A. C., Escorsi-Rosset, S. R., Wichert-Ana, L., Terra, V. C., Alexandre, V. , J., Araujo, D. , J., dos Santos, A. C., et al. (2013). Cognitive and Surgical Outcome in Mesial Temporal Lobe Epilepsy Associated with Hippocampal Sclerosis Plus Neurocysticercosis: A Cohort Study. Plos One 8:e60949.
Bianchin, M.M., et al., 2013. Cognitive and Surgical Outcome in Mesial Temporal Lobe Epilepsy Associated with Hippocampal Sclerosis Plus Neurocysticercosis: A Cohort Study. Plos One, 8(4): e60949.
M.M. Bianchin, et al., “Cognitive and Surgical Outcome in Mesial Temporal Lobe Epilepsy Associated with Hippocampal Sclerosis Plus Neurocysticercosis: A Cohort Study”, Plos One, vol. 8, 2013, : e60949.
Bianchin, M.M., Velasco, T.R., Coimbra, E.R., Gargaro, A.C., Escorsi-Rosset, S.R., Wichert-Ana, L., Terra, V.C., Alexandre, V., J., Araujo, D., J., dos Santos, A.C., Fernandes, R.M.F., Assirati, J.A., J., Carlotti, C.G., J., Leite, J.P., Takayanagui, O.M., Markowitsch, H.J., Sakamoto, A.C.: Cognitive and Surgical Outcome in Mesial Temporal Lobe Epilepsy Associated with Hippocampal Sclerosis Plus Neurocysticercosis: A Cohort Study. Plos One. 8, : e60949 (2013).
Bianchin, Marino M., Velasco, Tonicarlo R., Coimbra, Erica R., Gargaro, Ana C., Escorsi-Rosset, Sara R., Wichert-Ana, Lauro, Terra, Vera C., Alexandre, Veriano, Jr., Araujo, David, Jr., dos Santos, Antonio Carlos, Fernandes, Regina M. F., Assirati, Joao A., Jr., Carlotti, Carlos G., Jr., Leite, Joao P., Takayanagui, Osvaldo M., Markowitsch, Hans J., and Sakamoto, Americo C. “Cognitive and Surgical Outcome in Mesial Temporal Lobe Epilepsy Associated with Hippocampal Sclerosis Plus Neurocysticercosis: A Cohort Study”. Plos One 8.4 (2013): e60949.

13 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

The Association Between Neurocysticercosis and Hippocampal Atrophy is Related to Age.
Del Brutto OH, Issa NP, Salgado P, Del Brutto VJ, Zambrano M, Lama J, García HH., Am J Trop Med Hyg 96(1), 2017
PMID: 28077750
Update on Cysticercosis Epileptogenesis: the Role of the Hippocampus.
Del Brutto OH, Engel J, Eliashiv DS, García HH., Curr Neurol Neurosci Rep 16(1), 2016
PMID: 26659841
Pathogenesis of Taenia solium taeniasis and cysticercosis.
Gonzales I, Rivera JT, Garcia HH, Cysticercosis Working Group in Peru., Parasite Immunol 38(3), 2016
PMID: 26824681
Long-term seizure outcome for international consensus classification of hippocampal sclerosis: a survival analysis.
Na M, Ge H, Shi C, Shen H, Wang Y, Pu S, Liu L, Wang H, Xie C, Zhu M, Wang J, Shi C, Lin Z., Seizure 25(), 2015
PMID: 25455728
Calcified neurocysticercosis associates with hippocampal atrophy: a population-based study.
Del Brutto OH, Salgado P, Lama J, Del Brutto VJ, Campos X, Zambrano M, García HH., Am J Trop Med Hyg 92(1), 2015
PMID: 25349375
Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis.
Meguins LC, Adry RA, Silva Júnior SC, Pereira CU, Oliveira JG, Morais DF, Araújo Filho GM, Marques LH., Arq Neuropsiquiatr 73(12), 2015
PMID: 26677122
Prognostic value of CA4/DG volumetry with 3T magnetic resonance imaging on postoperative outcome of epilepsy patients with dentate gyrus pathology.
Na M, Liu Y, Shi C, Gao W, Ge H, Wang Y, Wang H, Long Y, Shen H, Shi C, Lin Z., Epilepsy Res 108(8), 2014
PMID: 25085233
Characteristics of mesial temporal lobe epilepsy associated with hippocampal sclerosis plus neurocysticercosis.
Bianchin MM, Velasco TR, Wichert-Ana L, Alexandre V, Araujo D, dos Santos AC, Carlotti CG, Takayanagui OM, Sakamoto AC., Epilepsy Res 108(10), 2014
PMID: 25306064

46 References

Daten bereitgestellt von Europe PubMed Central.


AUTHOR UNKNOWN, 0
The global burden and stigma of epilepsy.
de Boer HM, Mula M, Sander JW., Epilepsy Behav 12(4), 2008
PMID: 18280210
Incidence of epilepsy: a systematic review and meta-analysis.
Ngugi AK, Kariuki SM, Bottomley C, Kleinschmidt I, Sander JW, Newton CR., Neurology 77(10), 2011
PMID: 21893672
N Engl J Med
AUTHOR UNKNOWN, 2001
Mesial temporal lobe epilepsy: what have we learned?
Engel J Jr., Neuroscientist 7(4), 2001
PMID: 11488399
Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial.
Engel J Jr, McDermott MP, Wiebe S, Langfitt JT, Stern JM, Dewar S, Sperling MR, Gardiner I, Erba G, Fried I, Jacobs M, Vinters HV, Mintzer S, Kieburtz K; Early Randomized Surgical Epilepsy Trial (ERSET) Study Group, Blum D, Chung S, Treiman D, Passaro EA, Browne DR, Foldvary-Schaefer N, Goodman R, Hauser W, Morrell MJ, Henry TR, Halkar RK, Hudgins PA, Cole AJ, Hoch DB, Schachter SC, Salanova V, Krauss GL, Walczak TS, Boppana P, Willmore L, Barry JJ, Fisher RS, Risinger MW, Beach R, Kraemer DA, Vossler DG, Caplan R, Cunningham WE, Lopez-Rodriguez F, Mathern G, Shields W, Soss JR, Swarztrauber K, Vickrey BG, Buchtel HA, Minecan DN, Sagher O, Shih JJ, French JA, Berg M, Burchfiel J, Covert C, Watts A, Westerlund E, Van Ness PC, Fountain NB, Abou-Khalil B, Pellock JM, Gilliam F, Spencer D., JAMA 307(9), 2012
PMID: 22396514
Chronic epilepsy and cognition: a longitudinal study in temporal lobe epilepsy.
Helmstaedter C, Kurthen M, Lux S, Reuber M, Elger CE., Ann. Neurol. 54(4), 2003
PMID: 14520652
Neuropsychological aspects of epilepsy surgery.
Helmstaedter C., Epilepsy Behav 5 Suppl 1(), 2004
PMID: 14725846
Neurocysticercosis: a review.
Del Brutto OH., ScientificWorldJournal 2012(), 2012
PMID: 22312322
Neurocysticercosis: neglected but not forgotten.
Coyle CM, Mahanty S, Zunt JR, Wallin MT, Cantey PT, White AC Jr, O'Neal SE, Serpa JA, Southern PM, Wilkins P, McCarthy AE, Higgs ES, Nash TE., PLoS Negl Trop Dis 6(5), 2012
PMID: 22666505
The impact of neurocysticercosis in california: a review of hospitalized cases.
Croker C, Redelings M, Reporter R, Sorvillo F, Mascola L, Wilkins P., PLoS Negl Trop Dis 6(1), 2012
PMID: 22292097
Neurocysticercosis in Houston, Texas: an update.
Serpa JA, Graviss EA, Kass JS, White AC Jr., Medicine (Baltimore) 90(1), 2011
PMID: 21200189
Diagnosis and treatment of neurocysticercosis.
Nash TE, Garcia HH., Nat Rev Neurol 7(10), 2011
PMID: 21912406
Clinical manifestations associated with neurocysticercosis: a systematic review PLoS Negl Trop Dis
AUTHOR UNKNOWN, 2011
Spectrum of cognitive impairment in neurocysticercosis: differences according to disease phase.
Rodrigues CL, de Andrade DC, Livramento JA, Machado LR, Abraham R, Massaroppe L, Lucato LT, Caramelli P., Neurology 78(12), 2012
PMID: 22402863
Cognitive changes and quality of life in neurocysticercosis: a longitudinal study.
Wallin MT, Pretell EJ, Bustos JA, Caballero M, Alfaro M, Kane R, Wilken J, Sullivan C, Fratto T, Garcia HH., PLoS Negl Trop Dis 6(1), 2012
PMID: 22303492
Psychiatric manifestations of neurocysticercosis: a study of 38 patients from a neurology clinic in Brazil.
Forlenza OV, Filho AH, Nobrega JP, dos Ramos Machado L, de Barros NG, de Camargo CH, da Silva MF., J. Neurol. Neurosurg. Psychiatry 62(6), 1997
PMID: 9219748
Cognitive Performance of Patients with Epilepsy and Calcified Neurocysticercotic Lesions: A Case-Control Study.
Boppre MC, Wille PR, Guarnieri R, Rezek K, Carqueja C, Trevisol-Bittencourt PC, Walz JC, Bianchin M, von Wangenheim A, Chaves ML, Walz R., Epilepsy Behav 2(6), 2001
PMID: 12609389
Cognitive impairment and dementia in neurocysticercosis: a cross-sectional controlled study.
Ciampi de Andrade D, Rodrigues CL, Abraham R, Castro LH, Livramento JA, Machado LR, Leite CC, Caramelli P., Neurology 74(16), 2010
PMID: 20404310
Cognitive impairment and dementia in neurocysticercosis: a cross-sectional controlled study.
Bianchin MM, Dal Pizzol A, Scotta Cabral L, Martin KC, de Mello Rieder CR, Ciampi de Andrade D, Rodrigues CL, Castro LH, Machado LR, Caramelli P., Neurology 75(11), 2010
PMID: 20837974
Cognitive performance of patients with mesial temporal lobe epilepsy and incidental calcified neurocysticercosis.
Terra-Bustamante VC, Coimbra ER, Rezek KO, Escorsi-Rosset SR, Guarnieri R, Dalmagro CL, Inuzuka LM, Bianchin MM, Wichert-Ana L, Alexandre V, Takayanagui OM, Araujo D, dos Santos AC, Carlotti CG, Walz R, Markowitsch HJ, Sakamoto AC., J. Neurol. Neurosurg. Psychiatry 76(8), 2005
PMID: 16024883
Calcified neurocysticercotic lesions and postsurgery seizure control in temporal lobe epilepsy.
Leite JP, Terra-Bustamante VC, Fernandes RM, Santos AC, Chimelli L, Sakamoto AC, Assirati JA, Takayanagui OM., Neurology 55(10), 2000
PMID: 11094102
Surgical treatment for mesial temporal lobe epilepsy in the presence of massive calcified neurocysticercosis.
Wichert-Ana L, Velasco TR, Terra-Bustamante VC, Alexandre V Jr, Walz R, Bianchin MM, Leite JP, Assirati JA, Carlotti CG, Araujo D, Santos AC, Takayanagui OM, Sakamoto AC., Arch. Neurol. 61(7), 2004
PMID: 15262746
Cognitive reserve.
Stern Y., Neuropsychologia 47(10), 2009
PMID: 19467352
Calcified cysticercotic lesions and intractable epilepsy: a cross sectional study of 512 patients.
Velasco TR, Zanello PA, Dalmagro CL, Araujo D Jr, Santos AC, Bianchin MM, Alexandre V Jr, Walz R, Assirati JA, Carlotti CG Jr, Takayanagui OM, Sakamoto AC, Leite JP., J. Neurol. Neurosurg. Psychiatry 77(4), 2006
PMID: 16543527
Proposed diagnostic criteria for neurocysticercosis.
Del Brutto OH, Rajshekhar V, White AC Jr, Tsang VC, Nash TE, Takayanagui OM, Schantz PM, Evans CA, Flisser A, Correa D, Botero D, Allan JC, Sarti E, Gonzalez AE, Gilman RH, Garcia HH., Neurology 57(2), 2001
PMID: 11480424
What's wrong with Bonferroni adjustments.
Perneger TV., BMJ 316(7139), 1998
PMID: 9553006
Epidemiology of neurocysticercosis in Brazil.
Agapejev S., Rev. Inst. Med. Trop. Sao Paulo 38(3), 1996
PMID: 9163986
Calcific neurocysticercosis and epileptogenesis.
Nash TE, Del Brutto OH, Butman JA, Corona T, Delgado-Escueta A, Duron RM, Evans CA, Gilman RH, Gonzalez AE, Loeb JA, Medina MT, Pietsch-Escueta S, Pretell EJ, Takayanagui OM, Theodore W, Tsang VC, Garcia HH., Neurology 62(11), 2004
PMID: 15184592
Surgical treatment of limbic epilepsy associated with extrahippocampal lesions: the problem of dual pathology.
Levesque MF, Nakasato N, Vinters HV, Babb TL., J. Neurosurg. 75(3), 1991
PMID: 1869934
Operative strategy in patients with MRI-identified dual pathology and temporal lobe epilepsy.
Cascino GD, Jack CR Jr, Parisi JE, Sharbrough FW, Schreiber CP, Kelly PJ, Trenerry MR., Epilepsy Res. 14(2), 1993
PMID: 8453953
Surgical outcome in patients with epilepsy and dual pathology.
Li LM, Cendes F, Andermann F, Watson C, Fish DR, Cook MJ, Dubeau F, Duncan JS, Shorvon SD, Berkovic SF, Free S, Olivier A, Harkness W, Arnold DL., Brain 122 ( Pt 5)(), 1999
PMID: 10355666
Outcomes of epilepsy surgery in adults and children.
Spencer S, Huh L., Lancet Neurol 7(6), 2008
PMID: 18485316
Cognitive consequences of coexisting temporal lobe developmental malformations and hippocampal sclerosis.
Martin R, Dowler R, Gilliam F, Faught E, Morawetz R, Kuzniecky R., Neurology 53(4), 1999
PMID: 10489030
Epilepsy surgery outcome in coexisting symptomatic refractory focal epilepsy and benign focal epilepsy of childhood.
Wehner T, Lachhwani DK, Bingaman W, Haspolat S, Gupta A, Kotagal P, Tuxhorn I, Wyllie E., Pediatr. Neurol. 44(1), 2011
PMID: 21147388
Cysticercotic encephalitis: a severe form in young females.
Rangel R, Torres B, Del Bruto O, Sotelo J., Am. J. Trop. Med. Hyg. 36(2), 1987
PMID: 3826497
Neurocysticercosis, mesial temporal lobe epilepsy, and hippocampal sclerosis: an association largely ignored.
Bianchin MM, Velasco TR, Takayanagui OM, Sakamoto AC., Lancet Neurol 5(1), 2006
PMID: 16361019
Calcified neurocysticercosis lesions and hippocampal sclerosis: potential dual pathology?
Rathore C, Thomas B, Kesavadas C, Radhakrishnan K., Epilepsia 53(4), 2012
PMID: 22242912
How frequent is the association of neurocysticercosis and mesial temporal lobe epilepsy with hippocampal sclerosis? Epilepsia
AUTHOR UNKNOWN, 2010
Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®
Quellen

PMID: 23613762
PubMed | Europe PMC

Suchen in

Google Scholar