Quantitative 3D video microscopy of HIV transfer across T cell virological synapses

Hübner W, McNerney GP, Chen P, Dale BM, Gordon RE, Chuang FYS, Li X-D, Asmuth DM, Huser T, Chen BK (2009)
Science (New York, N.Y.) 323(5922): 1743-1747.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Hübner, WolfgangUniBi ; McNerney, Gregory P; Chen, Ping; Dale, Benjamin M; Gordon, Ronald E; Chuang, Frank Y S; Li, Xiao-Dong; Asmuth, David M; Huser, Thomas; Chen, Benjamin K
Abstract / Bemerkung
The spread of HIV between immune cells is greatly enhanced by cell-cell adhesions called virological synapses, although the underlying mechanisms have been unclear. With use of an infectious, fluorescent clone of HIV, we tracked the movement of Gag in live CD4 T cells and captured the direct translocation of HIV across the virological synapse. Quantitative, high-speed three-dimensional (3D) video microscopy revealed the rapid formation of micrometer-sized "buttons" containing oligomerized viral Gag protein. Electron microscopy showed that these buttons were packed with budding viral crescents. Viral transfer events were observed to form virus-laden internal compartments within target cells. Continuous time-lapse monitoring showed preferential infection through synapses. Thus, HIV dissemination may be enhanced by virological synapse-mediated cell adhesion coupled to viral endocytosis.
Transmission; Electron; Microscopy; Confocal; Microscopy; Jurkat Cells; Three-Dimensional; Imaging; Humans; HIV/ultrastructure; HIV/physiology; Endocytosis; Cytochalasin D/pharmacology; Coculture Techniques; Cell Adhesion; CD4-Positive T-Lymphocytes/virology; CD4-Positive T-Lymphocytes/physiology; CD4-Positive T-Lymphocytes/ultrastructure; Microscopy; Video; Receptors; CCR5/metabolism; Receptors; CXCR4/metabolism; Recombinant Fusion Proteins/metabolism; Virus Internalization; gag Gene Products; Human Immunodeficiency Virus/metabolism
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Hübner W, McNerney GP, Chen P, et al. Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science (New York, N.Y.). 2009;323(5922):1743-1747.
Hübner, W., McNerney, G. P., Chen, P., Dale, B. M., Gordon, R. E., Chuang, F. Y. S., Li, X. - D., et al. (2009). Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science (New York, N.Y.), 323(5922), 1743-1747. doi:10.1126/science.1167525
Hübner, Wolfgang, McNerney, Gregory P, Chen, Ping, Dale, Benjamin M, Gordon, Ronald E, Chuang, Frank Y S, Li, Xiao-Dong, Asmuth, David M, Huser, Thomas, and Chen, Benjamin K. 2009. “Quantitative 3D video microscopy of HIV transfer across T cell virological synapses”. Science (New York, N.Y.) 323 (5922): 1743-1747.
Hübner, W., McNerney, G. P., Chen, P., Dale, B. M., Gordon, R. E., Chuang, F. Y. S., Li, X. - D., Asmuth, D. M., Huser, T., and Chen, B. K. (2009). Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science (New York, N.Y.) 323, 1743-1747.
Hübner, W., et al., 2009. Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science (New York, N.Y.), 323(5922), p 1743-1747.
W. Hübner, et al., “Quantitative 3D video microscopy of HIV transfer across T cell virological synapses”, Science (New York, N.Y.), vol. 323, 2009, pp. 1743-1747.
Hübner, W., McNerney, G.P., Chen, P., Dale, B.M., Gordon, R.E., Chuang, F.Y.S., Li, X.-D., Asmuth, D.M., Huser, T., Chen, B.K.: Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science (New York, N.Y.). 323, 1743-1747 (2009).
Hübner, Wolfgang, McNerney, Gregory P, Chen, Ping, Dale, Benjamin M, Gordon, Ronald E, Chuang, Frank Y S, Li, Xiao-Dong, Asmuth, David M, Huser, Thomas, and Chen, Benjamin K. “Quantitative 3D video microscopy of HIV transfer across T cell virological synapses”. Science (New York, N.Y.) 323.5922 (2009): 1743-1747.

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Daten bereitgestellt von Europe PubMed Central.

Sequential trafficking of Env and Gag to HIV-1 T cell virological synapses revealed by live imaging.
Wang L, Izadmehr S, Kamau E, Kong XP, Chen BK., Retrovirology 16(1), 2019
PMID: 30646921
Experimental and computational analyses reveal that environmental restrictions shape HIV-1 spread in 3D cultures.
Imle A, Kumberger P, Schnellbächer ND, Fehr J, Carrillo-Bustamante P, Ales J, Schmidt P, Ritter C, Godinez WJ, Müller B, Rohr K, Hamprecht FA, Schwarz US, Graw F, Fackler OT., Nat Commun 10(1), 2019
PMID: 31086185
Efficient HIV-1 Trans Infection of CD4+ T Cells Occurs in the Presence of Antiretroviral Therapy.
Rappocciolo G, Sluis-Cremer N, Rinaldo CR., Open Forum Infect Dis 6(7), 2019
PMID: 31304185
A reaction-diffusion within-host HIV model with cell-to-cell transmission.
Ren X, Tian Y, Liu L, Liu X., J Math Biol 76(7), 2018
PMID: 29305736
All-Round Manipulation of the Actin Cytoskeleton by HIV.
Ospina Stella A, Turville S., Viruses 10(2), 2018
PMID: 29401736
Mechanisms for Cell-to-Cell Transmission of HIV-1.
Bracq L, Xie M, Benichou S, Bouchet J., Front Immunol 9(), 2018
PMID: 29515578
Distinct functions for the membrane-proximal ectodomain region (MPER) of HIV-1 gp41 in cell-free and cell-cell viral transmission and cell-cell fusion.
Narasimhulu VGS, Bellamy-McIntyre AK, Laumaea AE, Lay CS, Harrison DN, King HAD, Drummer HE, Poumbourios P., J Biol Chem 293(16), 2018
PMID: 29496992
Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death.
Jackson L, Hunter J, Cele S, Ferreira IM, Young AC, Karim F, Madansein R, Dullabh KJ, Chen CY, Buckels NJ, Ganga Y, Khan K, Boulle M, Lustig G, Neher RA, Sigal A., Elife 7(), 2018
PMID: 29555018
Live-Cell Imaging of Early Steps of Single HIV-1 Infection.
Francis AC, Melikyan GB., Viruses 10(5), 2018
PMID: 29783762
Super-resolution fluorescence microscopy studies of human immunodeficiency virus.
Chojnacki J, Eggeling C., Retrovirology 15(1), 2018
PMID: 29884197
Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts.
Torralba D, Baixauli F, Villarroya-Beltri C, Fernández-Delgado I, Latorre-Pellicer A, Acín-Pérez R, Martín-Cófreces NB, Jaso-Tamame ÁL, Iborra S, Jorge I, González-Aseguinolaza G, Garaude J, Vicente-Manzanares M, Enríquez JA, Mittelbrunn M, Sánchez-Madrid F., Nat Commun 9(1), 2018
PMID: 29985392
HIV-1 cell-to-cell transmission and broadly neutralizing antibodies.
Dufloo J, Bruel T, Schwartz O., Retrovirology 15(1), 2018
PMID: 30055632
Cytosolic Recognition of Microbes and Pathogens: Inflammasomes in Action.
Hayward JA, Mathur A, Ngo C, Man SM., Microbiol Mol Biol Rev 82(4), 2018
PMID: 30209070
Transmembrane TNF-α Facilitates HIV-1 Infection of Podocytes Cultured from Children with HIV-Associated Nephropathy.
Li J, Das JR, Tang P, Han Z, Jaiswal JK, Ray PE., J Am Soc Nephrol 28(3), 2017
PMID: 27811066
HIV-1 Activates T Cell Signaling Independently of Antigen to Drive Viral Spread.
Len ACL, Starling S, Shivkumar M, Jolly C., Cell Rep 18(4), 2017
PMID: 28122231
Controlling Multicycle Replication of Live-Attenuated HIV-1 Using an Unnatural Genetic Switch.
Yuan Z, Wang N, Kang G, Niu W, Li Q, Guo J., ACS Synth Biol 6(4), 2017
PMID: 28106981
Dendritic cell maturation, but not type I interferon exposure, restricts infection by HTLV-1, and viral transmission to T-cells.
Rizkallah G, Alais S, Futsch N, Tanaka Y, Journo C, Mahieux R, Dutartre H., PLoS Pathog 13(4), 2017
PMID: 28426803
Further Characterization of the Bifunctional HIV Entry Inhibitor sCD4-FIT45.
Falkenhagen A, Joshi S., Mol Ther Nucleic Acids 7(), 2017
PMID: 28624214
Mechanism of Anti-rotavirus Synergistic Activity by Epigallocatechin Gallate and a Proanthocyanidin-Containing Nutraceutical.
Lipson SM, Karalis G, Karthikeyan L, Ozen FS, Gordon RE, Ponnala S, Bao J, Samarrai W, Wolfe E., Food Environ Virol 9(4), 2017
PMID: 28466464
Spatial and temporal epithelial ovarian cancer cell heterogeneity impacts Maraba virus oncolytic potential.
Tong JG, Valdes YR, Sivapragasam M, Barrett JW, Bell JC, Stojdl D, DiMattia GE, Shepherd TG., BMC Cancer 17(1), 2017
PMID: 28854921
On the Whereabouts of HIV-1 Cellular Entry and Its Fusion Ports.
Jakobsdottir GM, Iliopoulou M, Nolan R, Alvarez L, Compton AA, Padilla-Parra S., Trends Mol Med 23(10), 2017
PMID: 28899754
Non-Neutralizing Antibodies Directed against HIV and Their Functions.
Mayr LM, Su B, Moog C., Front Immunol 8(), 2017
PMID: 29209323
T Cell-Macrophage Fusion Triggers Multinucleated Giant Cell Formation for HIV-1 Spreading.
Bracq L, Xie M, Lambelé M, Vu LT, Matz J, Schmitt A, Delon J, Zhou P, Randriamampita C, Bouchet J, Benichou S., J Virol 91(24), 2017
PMID: 28978713
Exploring the benefits of antibody immune response in HIV-1 infection using a discrete model.
Showa SP, Nyabadza F, Hove-Musekwa SD, Magombedze G., Math Med Biol 33(2), 2016
PMID: 25899531
HIV-1 Nucleocapsid Mimics the Membrane Adaptor Syntenin PDZ to Gain Access to ESCRTs and Promote Virus Budding.
Sette P, O'Connor SK, Yerramilli VS, Dussupt V, Nagashima K, Chutiraka K, Lingappa J, Scarlata S, Bouamr F., Cell Host Microbe 19(3), 2016
PMID: 26962944
Recent advances in human viruses imaging studies.
Florian PE, Rouillé Y, Ruta S, Nichita N, Roseanu A., J Basic Microbiol 56(6), 2016
PMID: 27059598
Optical micro-particle size detection by phase-generated carrier demodulation.
Li Q, Huang H, Lin F, Wu X., Opt Express 24(11), 2016
PMID: 27410073
Viruses exploit the tissue physiology of the host to spread in vivo.
Sewald X, Motamedi N, Mothes W., Curr Opin Cell Biol 41(), 2016
PMID: 27149407
In Vivo HIV-1 Cell-to-Cell Transmission Promotes Multicopy Micro-compartmentalized Infection.
Law KM, Komarova NL, Yewdall AW, Lee RK, Herrera OL, Wodarz D, Chen BK., Cell Rep 15(12), 2016
PMID: 27292632
Alpha-1-antitrypsin interacts with gp41 to block HIV-1 entry into CD4+ T lymphocytes.
Zhou X, Liu Z, Zhang J, Adelsberger JW, Yang J, Burton GF., BMC Microbiol 16(1), 2016
PMID: 27473095
Modeling Viral Spread.
Graw F, Perelson AS., Annu Rev Virol 3(1), 2016
PMID: 27618637
Recent Insights into the HIV/AIDS Pandemic.
Becerra JC, Bildstein LS, Gach JS., Microb Cell 3(9), 2016
PMID: 28357381
The Envelope Cytoplasmic Tail of HIV-1 Subtype C Contributes to Poor Replication Capacity through Low Viral Infectivity and Cell-to-Cell Transmission.
Santos da Silva E, Mulinge M, Lemaire M, Masquelier C, Beraud C, Rybicki A, Servais JY, Iserentant G, Schmit JC, Seguin-Devaux C, Perez Bercoff D., PLoS One 11(9), 2016
PMID: 27598717
Where in the Cell Are You? Probing HIV-1 Host Interactions through Advanced Imaging Techniques.
Dirk BS, Van Nynatten LR, Dikeakos JD., Viruses 8(10), 2016
PMID: 27775563
HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell.
Boullé M, Müller TG, Dähling S, Ganga Y, Jackson L, Mahamed D, Oom L, Lustig G, Neher RA, Sigal A., PLoS Pathog 12(11), 2016
PMID: 27812216
HIV Envelope gp120 Alters T Cell Receptor Mobilization in the Immunological Synapse of Uninfected CD4 T Cells and Augments T Cell Activation.
Deng J, Mitsuki YY, Shen G, Ray JC, Cicala C, Arthos J, Dustin ML, Hioe CE., J Virol 90(23), 2016
PMID: 27630246
Rapid 3D fluorescence imaging of individual optically trapped living immune cells.
Wolfson D, Steck M, Persson M, McNerney G, Popovich A, Goksör M, Huser T., J Biophotonics 8(3), 2015
PMID: 24420444
Contact-induced mitochondrial polarization supports HIV-1 virological synapse formation.
Groppelli E, Starling S, Jolly C., J Virol 89(1), 2015
PMID: 25320323
Receptors and routes of dengue virus entry into the host cells.
Cruz-Oliveira C, Freire JM, Conceição TM, Higa LM, Castanho MA, Da Poian AT., FEMS Microbiol Rev 39(2), 2015
PMID: 25725010
Distinct requirements for HIV-cell fusion and HIV-mediated cell-cell fusion.
Kondo N, Marin M, Kim JH, Desai TM, Melikyan GB., J Biol Chem 290(10), 2015
PMID: 25589785
Characterizing natural hydrogel for reconstruction of three-dimensional lymphoid stromal network to model T-cell interactions.
Kim J, Wu B, Niedzielski SM, Hill MT, Coleman RM, Ono A, Shikanov A., J Biomed Mater Res A 103(8), 2015
PMID: 25649205
HIV cell-to-cell transmission: effects on pathogenesis and antiretroviral therapy.
Agosto LM, Uchil PD, Mothes W., Trends Microbiol 23(5), 2015
PMID: 25766144
Development of a graded index microlens based fiber optical trap and its characterization using principal component analysis.
Nylk J, Kristensen MV, Mazilu M, Thayil AK, Mitchell CA, Campbell EC, Powis SJ, Gunn-Moore FJ, Dholakia K., Biomed Opt Express 6(4), 2015
PMID: 25909032
Cell-to-cell contact facilitates HIV transmission from lymphocytes to astrocytes via CXCR4.
Li GH, Anderson C, Jaeger L, Do T, Major EO, Nath A., AIDS 29(7), 2015
PMID: 25985398
Hybrid spreading mechanisms and T cell activation shape the dynamics of HIV-1 infection.
Zhang C, Zhou S, Groppelli E, Pellegrino P, Williams I, Borrow P, Chain BM, Jolly C., PLoS Comput Biol 11(4), 2015
PMID: 25837979
MIV-150/zinc acetate gel inhibits cell-associated simian-human immunodeficiency virus reverse transcriptase infection in a macaque vaginal explant model.
Barnable P, Calenda G, Bonnaire T, Menon R, Levendosky K, Gettie A, Blanchard J, Cooney ML, Fernández-Romero JA, Zydowsky TM, Teleshova N., Antimicrob Agents Chemother 59(7), 2015
PMID: 25870063
Dressing up Nanoparticles: A Membrane Wrap to Induce Formation of the Virological Synapse.
Yu X, Xu F, Ramirez NG, Kijewski SD, Akiyama H, Gummuluru S, Reinhard BM., ACS Nano 9(4), 2015
PMID: 25853367
In-cell infection: a novel pathway for Epstein-Barr virus infection mediated by cell-in-cell structures.
Ni C, Chen Y, Zeng M, Pei R, Du Y, Tang L, Wang M, Hu Y, Zhu H, He M, Wei X, Wang S, Ning X, Wang M, Wang J, Ma L, Chen X, Sun Q, Tang H, Wang Y, Wang X., Cell Res 25(7), 2015
PMID: 25916549
Exosomes are unlikely involved in intercellular Nef transfer.
Luo X, Fan Y, Park IW, He JJ., PLoS One 10(4), 2015
PMID: 25919665
Capacity of Broadly Neutralizing Antibodies to Inhibit HIV-1 Cell-Cell Transmission Is Strain- and Epitope-Dependent.
Reh L, Magnus C, Schanz M, Weber J, Uhr T, Rusert P, Trkola A., PLoS Pathog 11(7), 2015
PMID: 26158270
Commentary: Questioning the HIV-AIDS Hypothesis: 30 Years of Dissent.
Karetnikov A., Front Public Health 3(), 2015
PMID: 26301215
Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection.
Sewald X, Ladinsky MS, Uchil PD, Beloor J, Pi R, Herrmann C, Motamedi N, Murooka TT, Brehm MA, Greiner DL, Shultz LD, Mempel TR, Bjorkman PJ, Kumar P, Mothes W., Science 350(6260), 2015
PMID: 26429886
HIV-1-Induced Small T Cell Syncytia Can Transfer Virus Particles to Target Cells through Transient Contacts.
Symeonides M, Murooka TT, Bellfy LN, Roy NH, Mempel TR, Thali M., Viruses 7(12), 2015
PMID: 26703714
HIV entry: a game of hide-and-fuse?
Melikyan GB., Curr Opin Virol 4(), 2014
PMID: 24525288
Prostaglandin E2 reduces the release and infectivity of new cell-free virions and cell-to-cell HIV-1 transfer.
Clemente MI, Álvarez S, Serramía MJ, Martínez-Bonet M, Muñoz-Fernández MÁ., PLoS One 9(2), 2014
PMID: 24586238
Dendritic cell-lymphocyte cross talk downregulates host restriction factor SAMHD1 and stimulates HIV-1 replication in dendritic cells.
Su B, Biedma ME, Lederle A, Peressin M, Lambotin M, Proust A, Decoville T, Schmidt S, Laumond G, Moog C., J Virol 88(9), 2014
PMID: 24574390
Highly active antiretroviral therapies are effective against HIV-1 cell-to-cell transmission.
Agosto LM, Zhong P, Munro J, Mothes W., PLoS Pathog 10(2), 2014
PMID: 24586176
HIV-1 vaginal transmission: cell-free or cell-associated virus?
Barreto-de-Souza V, Arakelyan A, Margolis L, Vanpouille C., Am J Reprod Immunol 71(6), 2014
PMID: 24730358
Ezrin is a component of the HIV-1 virological presynapse and contributes to the inhibition of cell-cell fusion.
Roy NH, Lambelé M, Chan J, Symeonides M, Thali M., J Virol 88(13), 2014
PMID: 24760896
Which Antibody Functions are Important for an HIV Vaccine?
Su B, Moog C., Front Immunol 5(), 2014
PMID: 24995008
Three-dimensional imaging of HIV-1 virological synapses reveals membrane architectures involved in virus transmission.
Do T, Murphy G, Earl LA, Del Prete GQ, Grandinetti G, Li GH, Estes JD, Rao P, Trubey CM, Thomas J, Spector J, Bliss D, Nath A, Lifson JD, Subramaniam S., J Virol 88(18), 2014
PMID: 24965444
Early and late HIV-1 membrane fusion events are impaired by sphinganine lipidated peptides that target the fusion site.
Klug YA, Ashkenazi A, Viard M, Porat Z, Blumenthal R, Shai Y., Biochem J 461(2), 2014
PMID: 24766462
Live Cell Imaging of Retroviral Entry.
Hulme AE, Hope TJ., Annu Rev Virol 1(1), 2014
PMID: 26958731
Role of the nucleocapsid region in HIV-1 Gag assembly as investigated by quantitative fluorescence-based microscopy.
de Rocquigny H, El Meshri SE, Richert L, Didier P, Darlix JL, Mély Y., Virus Res 193(), 2014
PMID: 25016037
Three-Dimensional Imaging of Viral Infections.
Risco C, de Castro IF, Sanz-Sánchez L, Narayan K, Grandinetti G, Subramaniam S., Annu Rev Virol 1(1), 2014
PMID: 26958730
P2X-selective purinergic antagonists are strong inhibitors of HIV-1 fusion during both cell-to-cell and cell-free infection.
Swartz TH, Esposito AM, Durham ND, Hartmann BM, Chen BK., J Virol 88(19), 2014
PMID: 25031337
Adding new dimensions: towards an integrative understanding of HIV-1 spread.
Fackler OT, Murooka TT, Imle A, Mempel TR., Nat Rev Microbiol 12(8), 2014
PMID: 25029025
Cell-to-cell transfer of HIV infection: implications for HIV viral persistence.
Costiniuk CT, Jenabian MA., J Gen Virol 95(pt 11), 2014
PMID: 25146006
Distinct mechanisms regulate exposure of neutralizing epitopes in the V2 and V3 loops of HIV-1 envelope.
Upadhyay C, Mayr LM, Zhang J, Kumar R, Gorny MK, Nádas A, Zolla-Pazner S, Hioe CE., J Virol 88(21), 2014
PMID: 25165106
Renal epithelial cells produce and spread HIV-1 via T-cell contact.
Blasi M, Balakumaran B, Chen P, Negri DR, Cara A, Chen BK, Klotman ME., AIDS 28(16), 2014
PMID: 25062092
Probing the effect of force on HIV-1 receptor CD4.
Perez-Jimenez R, Alonso-Caballero A, Berkovich R, Franco D, Chen MW, Richard P, Badilla CL, Fernandez JM., ACS Nano 8(10), 2014
PMID: 25299596
Modeling mucosal cell-associated HIV type 1 transmission in vitro.
Anderson DJ., J Infect Dis 210 Suppl 3(), 2014
PMID: 25414419
Unique features of HIV-1 spread through T cell virological synapses.
Alvarez RA, Barría MI, Chen BK., PLoS Pathog 10(12), 2014
PMID: 25522148
The participation of plasma membrane hemichannels to purinergic signaling.
Baroja-Mazo A, Barberà-Cremades M, Pelegrín P., Biochim Biophys Acta 1828(1), 2013
PMID: 22266266
Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression.
Breed MW, Jordan AP, Aye PP, Lichtveld CF, Midkiff CC, Schiro FR, Haggarty BS, Sugimoto C, Alvarez X, Sandler NG, Douek DC, Kuroda MJ, Pahar B, Piatak M, Lifson JD, Keele BF, Hoxie JA, Lackner AA., J Virol 87(3), 2013
PMID: 23152518
A sensitive real-time PCR based assay to estimate the impact of amino acid substitutions on the competitive replication fitness of human immunodeficiency virus type 1 in cell culture.
Liu Y, Holte S, Rao U, McClure J, Konopa P, Swain JV, Lanxon-Cookson E, Kim M, Chen L, Mullins JI., J Virol Methods 189(1), 2013
PMID: 23201292
Cell-to-cell transmission of viruses.
Zhong P, Agosto LM, Munro JB, Mothes W., Curr Opin Virol 3(1), 2013
PMID: 23219376
Cell-cell transmission allows human T-lymphotropic virus 1 to circumvent tetherin restriction.
Ilinskaya A, Derse D, Hill S, Princler G, Heidecker G., Virology 436(1), 2013
PMID: 23260108
Relative contribution of free-virus and synaptic transmission to the spread of HIV-1 through target cell populations.
Komarova NL, Anghelina D, Voznesensky I, Trinité B, Levy DN, Wodarz D., Biol Lett 9(1), 2013
PMID: 23269844
Mechanisms of enhanced HIV spread through T-cell virological synapses.
Dale BM, Alvarez RA, Chen BK., Immunol Rev 251(1), 2013
PMID: 23278744
Transfer of extracellular vesicles during immune cell-cell interactions.
Gutiérrez-Vázquez C, Villarroya-Beltri C, Mittelbrunn M, Sánchez-Madrid F., Immunol Rev 251(1), 2013
PMID: 23278745
Synaptic transmission and the susceptibility of HIV infection to anti-viral drugs.
Komarova NL, Levy DN, Wodarz D., Sci Rep 3(), 2013
PMID: 23811684
Evidence of ongoing replication in a human immunodeficiency virus type 1 persistently infected cell line.
Olivares I, Sánchez-Jiménez C, Vieira CR, Toledano V, Gutiérrez-Rivas M, López-Galíndez C., J Gen Virol 94(pt 5), 2013
PMID: 23288426
Is specific HIV eradication from the brain possible or needed?
Brew BJ, Gray L, Lewin S, Churchill M., Expert Opin Biol Ther 13(3), 2013
PMID: 23289898
Cell-to-cell transmission can overcome multiple donor and target cell barriers imposed on cell-free HIV.
Zhong P, Agosto LM, Ilinskaya A, Dorjbal B, Truong R, Derse D, Uchil PD, Heidecker G, Mothes W., PLoS One 8(1), 2013
PMID: 23308151
Virus dynamics in the presence of synaptic transmission.
Komarova NL, Wodarz D., Math Biosci 242(2), 2013
PMID: 23357287
Live cell imaging of viral entry.
Sun E, He J, Zhuang X., Curr Opin Virol 3(1), 2013
PMID: 23395264
Forced virus evolution reveals functional crosstalk between the disulfide bonded region and membrane proximal ectodomain region of HIV-1 gp41.
Khasawneh AI, Laumaea A, Harrison DN, Bellamy-McIntyre AK, Drummer HE, Poumbourios P., Retrovirology 10(), 2013
PMID: 23618462
Productive entry of HIV-1 during cell-to-cell transmission via dynamin-dependent endocytosis.
Sloan RD, Kuhl BD, Mesplède T, Münch J, Donahue DA, Wainberg MA., J Virol 87(14), 2013
PMID: 23678185
Multiple proviral integration events after virological synapse-mediated HIV-1 spread.
Russell RA, Martin N, Mitar I, Jones E, Sattentau QJ., Virology 443(1), 2013
PMID: 23722103
The immunological synapse: the gateway to the HIV reservoir.
Kulpa DA, Brehm JH, Fromentin R, Cooper A, Cooper C, Ahlers J, Chomont N, Sékaly RP., Immunol Rev 254(1), 2013
PMID: 23772628
HIV-1 Nef promotes the localization of Gag to the cell membrane and facilitates viral cell-to-cell transfer.
Malbec M, Sourisseau M, Guivel-Benhassine F, Porrot F, Blanchet F, Schwartz O, Casartelli N., Retrovirology 10(), 2013
PMID: 23899341
Actin-binding protein drebrin regulates HIV-1-triggered actin polymerization and viral infection.
Gordón-Alonso M, Rocha-Perugini V, Álvarez S, Ursa Á, Izquierdo-Useros N, Martinez-Picado J, Muñoz-Fernández MA, Sánchez-Madrid F., J Biol Chem 288(39), 2013
PMID: 23926103
Fusion of mature HIV-1 particles leads to complete release of a gag-GFP-based content marker and raises the intraviral pH.
Padilla-Parra S, Marin M, Gahlaut N, Suter R, Kondo N, Melikyan GB., PLoS One 8(8), 2013
PMID: 23951066
Immune adaptor ADAP in T cells regulates HIV-1 transcription and cell-cell viral spread via different co-receptors.
Wei B, Han L, Abbink TE, Groppelli E, Lim D, Thaker YR, Gao W, Zhai R, Wang J, Lever A, Jolly C, Wang H, Rudd CE., Retrovirology 10(), 2013
PMID: 24047317
Intravital microscopy in BLT-humanized mice to study cellular dynamics in HIV infection.
Murooka TT, Mempel TR., J Infect Dis 208 Suppl 2(), 2013
PMID: 24151320
Can non-lytic CD8+ T cells drive HIV-1 escape?
Seich Al Basatena NK, Chatzimichalis K, Graw F, Frost SD, Regoes RR, Asquith B., PLoS Pathog 9(11), 2013
PMID: 24244151
Intracellular nucleic acid delivery by the supercharged dengue virus capsid protein.
Freire JM, Veiga AS, Conceição TM, Kowalczyk W, Mohana-Borges R, Andreu D, Santos NC, Da Poian AT, Castanho MA., PLoS One 8(12), 2013
PMID: 24339931
Protease inhibitors effectively block cell-to-cell spread of HIV-1 between T cells.
Titanji BK, Aasa-Chapman M, Pillay D, Jolly C., Retrovirology 10(), 2013
PMID: 24364896
Real-time optical detection of single human and bacterial viruses based on dark-field interferometry.
Mitra A, Ignatovich F, Novotny L., Biosens Bioelectron 31(1), 2012
PMID: 22169818
Macrophage internal HIV-1 is protected from neutralizing antibodies.
Koppensteiner H, Banning C, Schneider C, Hohenberg H, Schindler M., J Virol 86(5), 2012
PMID: 22205742
In vivo imaging of virological synapses.
Sewald X, Gonzalez DG, Haberman AM, Mothes W., Nat Commun 3(), 2012
PMID: 23271654
Cannabinoid receptor 2-mediated attenuation of CXCR4-tropic HIV infection in primary CD4+ T cells.
Costantino CM, Gupta A, Yewdall AW, Dale BM, Devi LA, Chen BK., PLoS One 7(3), 2012
PMID: 22448282
Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies.
Abela IA, Berlinger L, Schanz M, Reynell L, Günthard HF, Rusert P, Trkola A., PLoS Pathog 8(4), 2012
PMID: 22496655
Neutralization resistance of virological synapse-mediated HIV-1 Infection is regulated by the gp41 cytoplasmic tail.
Durham ND, Yewdall AW, Chen P, Lee R, Zony C, Robinson JE, Chen BK., J Virol 86(14), 2012
PMID: 22553332
Quantitative live-cell imaging of human immunodeficiency virus (HIV-1) assembly.
Baumgärtel V, Müller B, Lamb DC., Viruses 4(5), 2012
PMID: 22754649
Increased burst size in multiply infected cells can alter basic virus dynamics.
Cummings KW, Levy DN, Wodarz D., Biol Direct 7(), 2012
PMID: 22569346
Modulation of HIV pathogenesis and T-cell signaling by HIV-1 Nef.
Saxena SK, Shrivastava G, Tiwari S, Swamy MA, Nair MP., Future Virol 7(6), 2012
PMID: 22844345
Mobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cells.
Aggarwal A, Iemma TL, Shih I, Newsome TP, McAllery S, Cunningham AL, Turville SG., PLoS Pathog 8(6), 2012
PMID: 22685410
Antiretroviral agents effectively block HIV replication after cell-to-cell transfer.
Permanyer M, Ballana E, Ruiz A, Badia R, Riveira-Munoz E, Gonzalo E, Clotet B, Esté JA., J Virol 86(16), 2012
PMID: 22696642
HIV-1 assembly, budding, and maturation.
Sundquist WI, Kräusslich HG., Cold Spring Harb Perspect Med 2(7), 2012
PMID: 22762019
Ectopic ATP synthase facilitates transfer of HIV-1 from antigen-presenting cells to CD4(+) target cells.
Yavlovich A, Viard M, Zhou M, Veenstra TD, Wang JM, Gong W, Heldman E, Blumenthal R, Raviv Y., Blood 120(6), 2012
PMID: 22753871
Nanofluidic preconcentration and detection of nanoparticles.
Mitra A, Ignatovich F, Novotny L., J Appl Phys 112(1), 2012
PMID: 22865933
Dynamic Association between HIV-1 Gag and Membrane Domains.
Hogue IB, Llewellyn GN, Ono A., Mol Biol Int 2012(), 2012
PMID: 22830021
A hybrid stochastic-deterministic computational model accurately describes spatial dynamics and virus diffusion in HIV-1 growth competition assay.
Immonen T, Gibson R, Leitner T, Miller MA, Arts EJ, Somersalo E, Calvetti D., J Theor Biol 312(), 2012
PMID: 22814476
Trans-infection but not infection from within endosomal compartments after cell-to-cell HIV-1 transfer to CD4+ T cells.
Permanyer M, Ballana E, Badia R, Pauls E, Clotet B, Esté JA., J Biol Chem 287(38), 2012
PMID: 22846998
HIV-infected T cells are migratory vehicles for viral dissemination.
Murooka TT, Deruaz M, Marangoni F, Vrbanac VD, Seung E, von Andrian UH, Tager AM, Luster AD, Mempel TR., Nature 490(7419), 2012
PMID: 22854780
As good as it gets? The problem of HIV persistence despite antiretroviral drugs.
Sigal A, Baltimore D., Cell Host Microbe 12(2), 2012
PMID: 22901535
HIV: cell binding and entry.
Wilen CB, Tilton JC, Doms RW., Cold Spring Harb Perspect Med 2(8), 2012
PMID: 22908191
Tetherin/BST-2 is essential for the formation of the intracellular virus-containing compartment in HIV-infected macrophages.
Chu H, Wang JJ, Qi M, Yoon JJ, Chen X, Wen X, Hammonds J, Ding L, Spearman P., Cell Host Microbe 12(3), 2012
PMID: 22980332
Innate immune recognition of HIV-1.
Iwasaki A., Immunity 37(3), 2012
PMID: 22999945
Neutralizing antibodies inhibit HIV-1 transfer from primary dendritic cells to autologous CD4 T lymphocytes.
Su B, Xu K, Lederle A, Peressin M, Biedma ME, Laumond G, Schmidt S, Decoville T, Proust A, Lambotin M, Holl V, Moog C., Blood 120(18), 2012
PMID: 22955927
Alphaherpesvirus axon-to-cell spread involves limited virion transmission.
Taylor MP, Kobiler O, Enquist LW., Proc Natl Acad Sci U S A 109(42), 2012
PMID: 23027939
Pathways of cell-cell transmission of HTLV-1.
Pique C, Jones KS., Front Microbiol 3(), 2012
PMID: 23109932
HIV-specific antibody-dependent cellular cytotoxicity: a novel vaccine modality.
Madhavi V, Kent SJ, Stratov I., Expert Rev Clin Immunol 8(8), 2012
PMID: 23167688
Effect of synaptic transmission on viral fitness in HIV infection.
Komarova NL, Levy DN, Wodarz D., PLoS One 7(11), 2012
PMID: 23166585
T cell virological synapses and HIV-1 pathogenesis.
Chen BK., Immunol Res 54(1-3), 2012
PMID: 22477441
Tracking and quantitation of fluorescent HIV during cell-to-cell transmission.
Dale BM, McNerney GP, Hübner W, Huser TR, Chen BK., Methods 53(1), 2011
PMID: 20627127
HIV-1 transmission in the male genital tract.
Ganor Y, Bomsel M., Am J Reprod Immunol 65(3), 2011
PMID: 21114566
Innate sensing of HIV-infected cells.
Lepelley A, Louis S, Sourisseau M, Law HK, Pothlichet J, Schilte C, Chaperot L, Plumas J, Randall RE, Si-Tahar M, Mammano F, Albert ML, Schwartz O., PLoS Pathog 7(2), 2011
PMID: 21379343
Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells.
Chen P, Chen BK, Mosoian A, Hays T, Ross MJ, Klotman PE, Klotman ME., J Am Soc Nephrol 22(3), 2011
PMID: 21335514
Coreceptors and HIV-1 pathogenesis.
Gorry PR, Ancuta P., Curr HIV/AIDS Rep 8(1), 2011
PMID: 21188555
Early events of HIV-1 infection: can signaling be the next therapeutic target?
Jones KL, Smyth RP, Pereira CF, Cameron PU, Lewin SR, Jaworowski A, Mak J., J Neuroimmune Pharmacol 6(2), 2011
PMID: 21373988
Multiploid inheritance of HIV-1 during cell-to-cell infection.
Del Portillo A, Tripodi J, Najfeld V, Wodarz D, Levy DN, Chen BK., J Virol 85(14), 2011
PMID: 21543479
Viral determinants of polarized assembly for the murine leukemia virus.
Jin J, Li F, Mothes W., J Virol 85(15), 2011
PMID: 21593177
Host factors involved in retroviral budding and release.
Martin-Serrano J, Neil SJ., Nat Rev Microbiol 9(7), 2011
PMID: 21677686
Visualizing HIV-1 assembly.
Jouvenet N, Simon SM, Bieniasz PD., J Mol Biol 410(4), 2011
PMID: 21762796
New insights into HIV assembly and trafficking.
Balasubramaniam M, Freed EO., Physiology (Bethesda) 26(4), 2011
PMID: 21841072
Lensfree super-resolution holographic microscopy using wetting films on a chip.
Mudanyali O, Bishara W, Ozcan A., Opt Express 19(18), 2011
PMID: 21935102
HIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA).
Hioe CE, Tuen M, Vasiliver-Shamis G, Alvarez Y, Prins KC, Banerjee S, Nádas A, Cho MW, Dustin ML, Kachlany SC., PLoS One 6(8), 2011
PMID: 21850260
Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection.
Séror C, Melki MT, Subra F, Raza SQ, Bras M, Saïdi H, Nardacci R, Voisin L, Paoletti A, Law F, Martins I, Amendola A, Abdul-Sater AA, Ciccosanti F, Delelis O, Niedergang F, Thierry S, Said-Sadier N, Lamaze C, Métivier D, Estaquier J, Fimia GM, Falasca L, Casetti R, Modjtahedi N, Kanellopoulos J, Mouscadet JF, Ojcius DM, Piacentini M, Gougeon ML, Kroemer G, Perfettini JL., J Exp Med 208(9), 2011
PMID: 21859844
Live-cell real-time imaging reveals role of mitochondria in cell-to-cell transmission of HIV-1.
Lee-Huang S, Lin Huang P, Lee Huang P., Biochem Biophys Res Commun 415(2), 2011
PMID: 22037455
An inducible cell-cell fusion system with integrated ability to measure the efficiency and specificity of HIV-1 entry inhibitors.
Herschhorn A, Finzi A, Jones DM, Courter JR, Sugawara A, Smith AB, Sodroski JG., PLoS One 6(11), 2011
PMID: 22069466
For HIV, it's never too late to grow up.
Thali M., Cell Host Microbe 10(6), 2011
PMID: 22177555
Cell-to-cell transfer of HIV-1 via virological synapses leads to endosomal virion maturation that activates viral membrane fusion.
Dale BM, McNerney GP, Thompson DL, Hubner W, de Los Reyes K, Chuang FY, Huser T, Chen BK., Cell Host Microbe 10(6), 2011
PMID: 22177560
Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition.
Martin N, Welsch S, Jolly C, Briggs JA, Vaux D, Sattentau QJ., J Virol 84(7), 2010
PMID: 20089656
Quantitative comparison of HTLV-1 and HIV-1 cell-to-cell infection with new replication dependent vectors.
Mazurov D, Ilinskaya A, Heidecker G, Lloyd P, Derse D., PLoS Pathog 6(2), 2010
PMID: 20195464
Immunology and the elusive AIDS vaccine.
Virgin HW, Walker BD., Nature 464(7286), 2010
PMID: 20220841
Polymer live-cell array for real-time kinetic imaging of immune cells.
Zurgil N, Afrimzon E, Deutsch A, Namer Y, Shafran Y, Sobolev M, Tauber Y, Ravid-Hermesh O, Deutsch M., Biomaterials 31(18), 2010
PMID: 20346503
Manipulating CD4+ T cells by optical tweezers for the initiation of cell-cell transfer of HIV-1.
McNerney GP, Hübner W, Chen BK, Huser T., J Biophotonics 3(4), 2010
PMID: 20301121
HIV-1 assembly in macrophages.
Benaroch P, Billard E, Gaudin R, Schindler M, Jouve M., Retrovirology 7(), 2010
PMID: 20374631
Virus cell-to-cell transmission.
Mothes W, Sherer NM, Jin J, Zhong P., J Virol 84(17), 2010
PMID: 20375157
HIV-1 assembly at the plasma membrane.
Ono A., Vaccine 28 Suppl 2(), 2010
PMID: 20510745
HIV-1 Virological Synapse is not Simply a Copycat of the Immunological Synapse.
Vasiliver-Shamis G, Dustin ML, Hioe CE., Viruses 2(5), 2010
PMID: 20890395
Potent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1.
Zhang MY, Borges AR, Ptak RG, Wang Y, Dimitrov AS, Alam SM, Wieczorek L, Bouma P, Fouts T, Jiang S, Polonis VR, Haynes BF, Quinnan GV, Montefiori DC, Dimitrov DS., MAbs 2(3), 2010
PMID: 20305395
Role of the C-terminal domain of the HIV-1 glycoprotein in cell-to-cell viral transmission between T lymphocytes.
Emerson V, Haller C, Pfeiffer T, Fackler OT, Bosch V., Retrovirology 7(), 2010
PMID: 20459872
T cell polarization at the virological synapse.
Jolly C., Viruses 2(6), 2010
PMID: 21994679
Cell-to-Cell Spread of Retroviruses.
Sattentau QJ., Viruses 2(6), 2010
PMID: 21994681
Tetherin restricts productive HIV-1 cell-to-cell transmission.
Casartelli N, Sourisseau M, Feldmann J, Guivel-Benhassine F, Mallet A, Marcelin AG, Guatelli J, Schwartz O., PLoS Pathog 6(6), 2010
PMID: 20585562
Within 1 h, HIV-1 uses viral synapses to enter efficiently the inner, but not outer, foreskin mucosa and engages Langerhans-T cell conjugates.
Ganor Y, Zhou Z, Tudor D, Schmitt A, Vacher-Lavenu MC, Gibault L, Thiounn N, Tomasini J, Wolf JP, Bomsel M., Mucosal Immunol 3(5), 2010
PMID: 20571487
The HTLV-1 Virological Synapse.
Nejmeddine M, Bangham CR., Viruses 2(7), 2010
PMID: 21994688
ADS-J1 inhibits HIV-1 entry by interacting with gp120 and does not block fusion-active gp41 core formation.
González-Ortega E, Mena MP, Permanyer M, Ballana E, Clotet B, Esté JA., Antimicrob Agents Chemother 54(10), 2010
PMID: 20643898
Macrophages and Cell-Cell Spread of HIV-1.
Waki K, Freed EO., Viruses 2(8), 2010
PMID: 21552427
HIV-1 Virological Synapse: Live Imaging of Transmission.
Feldmann J, Schwartz O., Viruses 2(8), 2010
PMID: 21994700
Tethered virions are intermediates in the assembly and release of HIV-1 particles.
Karetnikov A, Suomalainen M., Virology 407(2), 2010
PMID: 20850859
Visualizing cell-to-cell transfer of HIV using fluorescent clones of HIV and live confocal microscopy.
Dale B, McNerney GP, Thompson DL, Hübner W, Huser T, Chen BK., J Vis Exp (44), 2010
PMID: 20972408
In silico modeling indicates the development of HIV-1 resistance to multiple shRNA gene therapy differs to standard antiretroviral therapy.
Applegate TL, Birkett DJ, Mcintyre GJ, Jaramillo AB, Symonds G, Murray JM., Retrovirology 7(), 2010
PMID: 20932334
Tetherin restricts direct cell-to-cell infection of HIV-1.
Kuhl BD, Sloan RD, Donahue DA, Bar-Magen T, Liang C, Wainberg MA., Retrovirology 7(), 2010
PMID: 21184674
HIV endocytosis after dendritic cell to T cell viral transfer leads to productive virus infection.
Clotet-Codina I, Bosch B, Senserrich J, Fernández-Figueras MT, Peña R, Ballana E, Bofill M, Clotet B, Esté JA., Antiviral Res 83(1), 2009
PMID: 19501262
Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses.
Rudnicka D, Feldmann J, Porrot F, Wietgrefe S, Guadagnini S, Prévost MC, Estaquier J, Haase AT, Sol-Foulon N, Schwartz O., J Virol 83(12), 2009
PMID: 19369333
HIV Entry Revisited.
Uchil PD, Mothes W., Cell 137(3), 2009
PMID: 19410537
Formation of syncytia is repressed by tetraspanins in human immunodeficiency virus type 1-producing cells.
Weng J, Krementsov DN, Khurana S, Roy NH, Thali M., J Virol 83(15), 2009
PMID: 19458002
The cell biology of HIV-1 virion genesis.
Bieniasz PD., Cell Host Microbe 5(6), 2009
PMID: 19527882
Differential role of autophagy in CD4 T cells and macrophages during X4 and R5 HIV-1 infection.
Espert L, Varbanov M, Robert-Hebmann V, Sagnier S, Robbins I, Sanchez F, Lafont V, Biard-Piechaczyk M., PLoS One 4(6), 2009
PMID: 19492063
HTLV-1-Tax and ICAM-1 act on T-cell signal pathways to polarize the microtubule-organizing center at the virological synapse.
Nejmeddine M, Negi VS, Mukherjee S, Tanaka Y, Orth K, Taylor GP, Bangham CR., Blood 114(5), 2009
PMID: 19494354
Assembly of the murine leukemia virus is directed towards sites of cell-cell contact.
Jin J, Sherer NM, Heidecker G, Derse D, Mothes W., PLoS Biol 7(7), 2009
PMID: 19636361
Cell carriers for oncolytic viruses: Fed Ex for cancer therapy.
Willmon C, Harrington K, Kottke T, Prestwich R, Melcher A, Vile R., Mol Ther 17(10), 2009
PMID: 19690519
On the steps of cell-to-cell HIV transmission between CD4 T cells.
Puigdomènech I, Massanella M, Cabrera C, Clotet B, Blanco J., Retrovirology 6(), 2009
PMID: 19825175
Dynamics of HIV-1 assembly and release.
Ivanchenko S, Godinez WJ, Lampe M, Kräusslich HG, Eils R, Rohr K, Bräuchle C, Müller B, Lamb DC., PLoS Pathog 5(11), 2009
PMID: 19893629

26 References

Daten bereitgestellt von Europe PubMed Central.

Endocytic entry of HIV-1.
Fackler OT, Peterlin BM., Curr. Biol. 10(16), 2000
PMID: 10985390
Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton.
Igakura T, Stinchcombe JC, Goon PK, Taylor GP, Weber JN, Griffiths GM, Tanaka Y, Osame M, Bangham CR., Science 299(5613), 2003
PMID: 12589003
Recruitment of HIV and its receptors to dendritic cell-T cell junctions.
McDonald D, Wu L, Bohks SM, KewalRamani VN, Unutmaz D, Hope TJ., Science 300(5623), 2003
PMID: 12730499
HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse.
Jolly C, Kashefi K, Hollinshead M, Sattentau QJ., J. Exp. Med. 199(2), 2004
PMID: 14734528
Coupling of human immunodeficiency virus type 1 fusion to virion maturation: a novel role of the gp41 cytoplasmic tail.
Wyma DJ, Jiang J, Shi J, Zhou J, Lineberger JE, Miller MD, Aiken C., J. Virol. 78(7), 2004
PMID: 15016865
An improved cyan fluorescent protein variant useful for FRET.
Rizzo MA, Springer GH, Granada B, Piston DW., Nat. Biotechnol. 22(4), 2004
PMID: 14990965
Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4+ T cells.
Cameron PU, Freudenthal PS, Barker JM, Gezelter S, Inaba K, Steinman RM., Science 257(5068), 1992
PMID: 1352913
Quantitation of human immunodeficiency virus type 1 infection kinetics.
Dimitrov DS, Willey RL, Sato H, Chang LJ, Blumenthal R, Martin MA., J. Virol. 67(4), 1993
PMID: 8445728
The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells.
Cohen GB, Gandhi RT, Davis DM, Mandelboim O, Chen BK, Strominger JL, Baltimore D., Immunity 10(6), 1999
PMID: 10403641
High level of coreceptor-independent HIV transfer induced by contacts between primary CD4 T cells.
Blanco J, Bosch B, Fernandez-Figueras MT, Barretina J, Clotet B, Este JA., J. Biol. Chem. 279(49), 2004
PMID: 15371410
Regulation of human immunodeficiency virus type 1 envelope glycoprotein fusion by a membrane-interactive domain in the gp41 cytoplasmic tail.
Wyss S, Dimitrov AS, Baribaud F, Edwards TG, Blumenthal R, Hoxie JA., J. Virol. 79(19), 2005
PMID: 16160149
Perils at mucosal front lines for HIV and SIV and their hosts.
Haase AT., Nat. Rev. Immunol. 5(10), 2005
PMID: 16200081
Virus entry: open sesame.
Marsh M, Helenius A., Cell 124(4), 2006
PMID: 16497584
Dynamic imaging of the immune system: progress, pitfalls and promise.
Germain RN, Miller MJ, Dustin ML, Nussenzweig MC., Nat. Rev. Immunol. 6(7), 2006
PMID: 16799470
Inefficient human immunodeficiency virus replication in mobile lymphocytes.
Sourisseau M, Sol-Foulon N, Porrot F, Blanchet F, Schwartz O., J. Virol. 81(2), 2006
PMID: 17079292
ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation.
Sol-Foulon N, Sourisseau M, Porrot F, Thoulouze MI, Trouillet C, Nobile C, Blanchet F, di Bartolo V, Noraz N, Taylor N, Alcover A, Hivroz C, Schwartz O., EMBO J. 26(2), 2007
PMID: 17215865
Human immunodeficiency virus type 1 entry into macrophages mediated by macropinocytosis.
Marechal V, Prevost MC, Petit C, Perret E, Heard JM, Schwartz O., J. Virol. 75(22), 2001
PMID: 11602756

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