Stress eliminates retrieval-induced forgetting-Does the oral application of cortisol?

Koessler S, Steidle L, Engler H, Kißler J (2013)
Psychoneuroendocrinology 38(1): 94-106.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Koessler, Susanne; Steidle, Laura; Engler, Harald; Kißler, JohannaUniBi
Abstract / Bemerkung
It is well established that stress and glucocorticoids can affect memory. Psychosocial stress has been reported to eliminate retrieval-induced forgetting (RIF), the phenomenon that repeated retrieval of a subset of previously learned material impairs later recall of related, but non-retrieved information. The stress-related reduction of RIF has been found correlated with an increase in salivary cortisol levels. Based on these findings, the current placebo-controlled study examined the effect of an oral dose of 25 mg hydrocortisone on the RIF effect in 37 healthy men. Even though participants in the hydrocortisone group showed a marked increase in salivary cortisol, retrieval-induced forgetting was not affected by the pharmacological treatment. Thus, cortisol administration alone in contrast to stress experience does not impair the RIF effect. However, participants with high state anxiety during retrieval practice did not show RIF, whereas participants with low state anxiety did. This finding suggests a role for state anxiety in stress-related elimination of retrieval-induced forgetting, perhaps indicative of a memory-modulating sympathetic nervous system effect. (C) 2012 Elsevier Ltd. All rights reserved.
HPA-axis; Stress; Retrieval-induced forgetting; Cortisol; Memory; Anxiety
Page URI


Koessler S, Steidle L, Engler H, Kißler J. Stress eliminates retrieval-induced forgetting-Does the oral application of cortisol? Psychoneuroendocrinology. 2013;38(1):94-106.
Koessler, S., Steidle, L., Engler, H., & Kißler, J. (2013). Stress eliminates retrieval-induced forgetting-Does the oral application of cortisol? Psychoneuroendocrinology, 38(1), 94-106. doi:10.1016/j.psyneuen.2012.05.004
Koessler, Susanne, Steidle, Laura, Engler, Harald, and Kißler, Johanna. 2013. “Stress eliminates retrieval-induced forgetting-Does the oral application of cortisol?”. Psychoneuroendocrinology 38 (1): 94-106.
Koessler, S., Steidle, L., Engler, H., and Kißler, J. (2013). Stress eliminates retrieval-induced forgetting-Does the oral application of cortisol? Psychoneuroendocrinology 38, 94-106.
Koessler, S., et al., 2013. Stress eliminates retrieval-induced forgetting-Does the oral application of cortisol? Psychoneuroendocrinology, 38(1), p 94-106.
S. Koessler, et al., “Stress eliminates retrieval-induced forgetting-Does the oral application of cortisol?”, Psychoneuroendocrinology, vol. 38, 2013, pp. 94-106.
Koessler, S., Steidle, L., Engler, H., Kißler, J.: Stress eliminates retrieval-induced forgetting-Does the oral application of cortisol? Psychoneuroendocrinology. 38, 94-106 (2013).
Koessler, Susanne, Steidle, Laura, Engler, Harald, and Kißler, Johanna. “Stress eliminates retrieval-induced forgetting-Does the oral application of cortisol?”. Psychoneuroendocrinology 38.1 (2013): 94-106.

5 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Children's Forgetting of Pain-Related Memories.
Marche TA, Briere JL, von Baeyer CL., J Pediatr Psychol 41(2), 2016
PMID: 26666267
Differential effects of acute cortisol administration on deep and shallow episodic memory traces: a study on healthy males.
Cioncoloni D, Galli G, Mazzocchio R, Feurra M, Giovannelli F, Santarnecchi E, Bonifazi M, Rossi A, Rossi S., Neurobiol Learn Mem 114(), 2014
PMID: 24954843

91 References

Daten bereitgestellt von Europe PubMed Central.

Cortisol variation in humans affects memory for emotionally laden and neutral information.
Abercrombie HC, Kalin NH, Thurow ME, Rosenkranz MA, Davidson RJ., Behav. Neurosci. 117(3), 2003
PMID: 12802879
The effect of practice on recall of emotional information in individuals with generalized social phobia.
Amir N, Coles ME, Brigidi B, Foa EB., J Abnorm Psychol 110(1), 2001
PMID: 11261403
Remembering can cause forgetting: retrieval dynamics in long-term memory.
Anderson MC, Bjork RA, Bjork EL., J Exp Psychol Learn Mem Cogn 20(5), 1994
PMID: 7931095
Stress impairs prefrontal cortical function in rats and monkeys: role of dopamine D1 and norepinephrine [alpha]-1 receptor mechanisms
Arnsten, 2000
Individual differences in working memory capacity predict retrieval-induced forgetting.
Aslan A, Bauml KH., J Exp Psychol Learn Mem Cogn 37(1), 2011
PMID: 21090906
Category norms of verbal items in 56 categories: A replication and extension of the Connecticut category norms
Battig, J. Exp. Psychol. 80(3 (Pt 2)), 1969
Remembering can cause forgetting--but not in negative moods.
Bauml KH, Kuhbandner C., Psychol Sci 18(2), 2007
PMID: 17425528
When remembering causes forgetting: retrieval-induced forgetting as recovery failure.
Bauml KH, Zellner M, Vilimek R., J Exp Psychol Learn Mem Cogn 31(6), 2005
PMID: 16393042
Measuring emotion: the Self-Assessment Manikin and the Semantic Differential.
Bradley MM, Lang PJ., J Behav Ther Exp Psychiatry 25(1), 1994
PMID: 7962581
Remembering pictures: pleasure and arousal in memory
Bradley, J. Exp. Psychol. Learn. 18(2), 1996
Inhibition in cued retrieval
Brown, J. Exp. Psychol.: Hum. Learn. 7(3), 1981
Enhanced memory for emotional material following stress-level cortisol treatment in humans.
Buchanan TW, Lovallo WR., Psychoneuroendocrinology 26(3), 2001
PMID: 11166493
Effects of instructions on measures of state and trait anxiety in flight students.
Bucky SF, Spielberger CD, Bale RM., J Appl Psychol 56(3), 1972
PMID: 5034819
Mechanisms of emotional arousal and lasting declarative memory.
Cahill L, McGaugh JL., Trends Neurosci. 21(7), 1998
PMID: 9683321
Noradrenergic modulation of working memory and emotional memory in humans.
Chamberlain SR, Muller U, Blackwell AD, Robbins TW, Sahakian BJ., Psychopharmacology (Berl.) 188(4), 2006
PMID: 16642355
Disruption of inhibitory control of memory following lesions to the frontal and temporal lobes
Conway, Cortex 39(4–5), 2003
Anxiety and working memory capacity
Darke, Cogn. Emot. 2(2), 1988
Stress and the brain: from adaptation to disease.
de Kloet ER, Joels M, Holsboer F., Nat. Rev. Neurosci. 6(6), 2005
PMID: 15891777
Glucocorticoid-induced impairment of declarative memory retrieval is associated with reduced blood flow in the medial temporal lobe.
de Quervain DJ, Henke K, Aerni A, Treyer V, McGaugh JL, Berthold T, Nitsch RM, Buck A, Roozendaal B, Hock C., Eur. J. Neurosci. 17(6), 2003
PMID: 12670318
Stress and glucocorticoids impair retrieval of long-term spatial memory.
de Quervain DJ, Roozendaal B, McGaugh JL., Nature 394(6695), 1998
PMID: 9723618
Acute cortisone administration impairs retrieval of long-term declarative memory in humans.
de Quervain DJ, Roozendaal B, Nitsch RM, McGaugh JL, Hock C., Nat. Neurosci. 3(4), 2000
PMID: 10725918
Adrenocortical responses to repeated parachute jumping and subsequent h-CRH challenge in inexperienced healthy subjects.
Deinzer R, Kirschbaum C, Gresele C, Hellhammer DH., Physiol. Behav. 61(4), 1997
PMID: 9108568
Stress-induced cortisol elevations are associated with impaired delayed, but not immediate recall.
Elzinga BM, Bakker A, Bremner JD., Psychiatry Res 134(3), 2005
PMID: 15892980

Fahrenberg, 2001
The heritability of hypothalamus pituitary adrenal axis responses to psychosocial stress is context dependent
Federenko, J. Clin. Endocr. Metab. 89(12), 2004
Retrieval-induced forgetting is inversely related to everyday cognitive failures
Groome, Br. J. Psychol. 96(3), 2005
Theta oscillations predict the detrimental effects of memory retrieval
Hanslmayr, Cogn. Affect. Behav. Neurosci. 10(3), 2011

Hautzinger, 1994

Hobi, 1985

Janke, 1997
When remembering causes forgetting: electrophysiological correlates of retrieval-induced forgetting.
Johansson M, Aslan A, Bauml KH, Gabel A, Mecklinger A., Cereb. Cortex 17(6), 2006
PMID: 16880224
Validating self-report measures of state and trait anxiety against a physiological measure
Kantor, Curr. Psychol. 20(), 2001
Salivary cortisol
Kirschbaum, 2000
The ‘Trier Social Stress Test’: a tool for investigating psychobiological stress responses in a laboratory setting
Kirschbaum, Neuropsychobiology 28(1–2), 1993
Stress- and treatment-induced elevations of cortisol levels associated with impaired declarative memory in healthy adults.
Kirschbaum C, Wolf OT, May M, Wippich W, Hellhammer DH., Life Sci. 58(17), 1996
PMID: 8622574
No retrieval-induced forgetting under stress.
Koessler S, Engler H, Riether C, Kissler J., Psychol Sci 20(11), 2009
PMID: 19818045
Does remembering cause forgetting in chronically stressed people? A study of Ugandan civil war refugees with and without PTSD
Koessler, J. Psychol. 218(2), 2010

Krampen, 1991
Untersuchungen mit einer deutschen Version der “Positive and Negative Affect Schedule” (PANAS)
Krohne, Diagnostica 42(2), 1996
Ten years of research with the Trier Social Stress Test-Revisited
Kudielka, 2007
Decreased demands on cognitive control reveal the neural processing benefits of forgetting.
Kuhl BA, Dudukovic NM, Kahn I, Wagner AD., Nat. Neurosci. 10(7), 2007
PMID: 17558403
Overcoming suppression in order to remember: contributions from anterior cingulate and ventrolateral prefrontal cortex.
Kuhl BA, Kahn I, Dudukovic NM, Wagner AD., Cogn Affect Behav Neurosci 8(2), 2008
PMID: 18589510
Impaired memory retrieval after psychosocial stress in healthy young men.
Kuhlmann S, Piel M, Wolf OT., J. Neurosci. 25(11), 2005
PMID: 15772357

Laux, 1981
The relationship between retrieval-induced forgetting, anxiety, and personality
Law, Anxiety Stress Coping (), 2011
Gone but not forgotten: the transient nature of retrieval-induced forgetting.
MacLeod MD, Macrae CN., Psychol Sci 12(2), 2001
PMID: 11340924
Produktionsnormen für verbale Reaktionen zu 40 geläufigen Kategorien
Mannhaupt, Sprache Kognit. 2(4), 1983
Stress and hippocampal plasticity: implications for the pathophysiology of affective disorders
McEwen, Hum. Psychopharm. Clin. 16(S1), 2001
Uptake of corticosterone by rat brain and its concentration by certain limbic structures.
McEwen BS, Weiss JM, Schwartz LS., Brain Res. 16(1), 1969
PMID: 5348850
Memory modulation
McGaugh, 2008
Amygdala norepinephrine levels after training predict inhibitory avoidance retention performance in rats.
McIntyre CK, Hatfield T, McGaugh JL., Eur. J. Neurosci. 16(7), 2002
PMID: 12405982
Glucocorticoids decrease hippocampal and prefrontal activation during declarative memory retrieval in young men
Oei, Brain Imaging Behav. 1(1–2), 2007
Psychosocial stress impairs working memory at high loads: an association with cortisol levels and memory retrieval.
Oei NY, Everaerd WT, Elzinga BM, van Well S, Bermond B., Stress 9(3), 2006
PMID: 17035163
Glucocorticoid effects on object recognition memory require training-associated emotional arousal.
Okuda S, Roozendaal B, McGaugh JL., Proc. Natl. Acad. Sci. U.S.A. 101(3), 2004
PMID: 14711996
Age-related differences in glucocorticoid receptor mRNA levels in the human brain.
Perlman WR, Webster MJ, Herman MM, Kleinman JE, Weickert CS., Neurobiol. Aging 28(3), 2006
PMID: 16540204
Retrieval blocks in episodic and semantic memory
Roediger, Can. J. Psychol. 36(2), 1982
Psychosocial stress-induced activation of salivary alpha-amylase: an indicator of sympathetic activity?
Rohleder, Ann. N.Y. Acad. Sci. 1032(1), 2004
Stress, memory and the amygdala.
Roozendaal B, McEwen BS, Chattarji S., Nat. Rev. Neurosci. 10(6), 2009
PMID: 19469026
Deutschsprachige Normen für Vertreter von 48 Kategorien
Scheithe, Sprache Kognit. 14(1), 1995

Schneewind, 1998
Psychosocial stress induces working memory impairments in an n-back paradigm.
Schoofs D, Preuss D, Wolf OT., Psychoneuroendocrinology 33(5), 2008
PMID: 18359168
Stress disrupts context-dependent memory.
Schwabe L, Bohringer A, Wolf OT., Learn. Mem. 16(2), 2009
PMID: 19181616
Modulation of spatial and stimulus-response learning strategies by exogenous cortisol in healthy young women.
Schwabe L, Oitzl MS, Richter S, Schachinger H., Psychoneuroendocrinology 34(3), 2008
PMID: 18990499
Memory formation under stress: quantity and quality.
Schwabe L, Wolf OT, Oitzl MS., Neurosci Biobehav Rev 34(4), 2009
PMID: 19931555

Steyer, 1997
Assessment of emotions: anxiety, anger, depression, and curiosity
Spielberger, Appl. Psychol. Health Wellbeing 1(3), 2009
Anxiety, reactivity, and social stress-induced cortisol elevation in humans
Takahashi, Neuroendocrinol. Lett. 26(4), 2005
Early adverse events, HPA activity and rostral anterior cingulate volume in MDD.
Treadway MT, Grant MM, Ding Z, Hollon SD, Gore JC, Shelton RC., PLoS ONE 4(3), 2009
PMID: 19325704
Neural regulation of endocrine and autonomic stress responses.
Ulrich-Lai YM, Herman JP., Nat. Rev. Neurosci. 10(6), 2009
PMID: 19469025
Regional specificity of brain glucocorticoid receptor mRNA alterations in subjects with schizophrenia and mood disorders.
Webster MJ, Knable MB, O'Grady J, Orthmann J, Weickert CS., Mol. Psychiatry 7(9), 2002
PMID: 12399952
Effects of acute psychosocial stress on working memory related brain activity in men.
Weerda R, Muehlhan M, Wolf OT, Thiel CM., Hum Brain Mapp 31(9), 2010
PMID: 20127868
Influence of age and relative weight on cortisol suppression in normal subjects.
Weiner MF, Davis BM, Mohs RC, Davis KL., Am J Psychiatry 144(5), 1987
PMID: 3578575
Neural markers of inhibition in human memory retrieval.
Wimber M, Bauml KH, Bergstrom Z, Markopoulos G, Heinze HJ, Richardson-Klavehn A., J. Neurosci. 28(50), 2008
PMID: 19074015
Retrieval from episodic memory: neural mechanisms of interference resolution.
Wimber M, Rutschmann RM, Greenlee MW, Bauml KH., J Cogn Neurosci 21(3), 2009
PMID: 18564040
Prefrontal dopamine and the dynamic control of human long-term memory.
Wimber M, Schott BH, Wendler F, Seidenbecher CI, Behnisch G, Macharadze T, Bauml KH, Richardson-Klavehn A., Transl Psychiatry 1(), 2011
PMID: 22832518
Stress and memory in humans: twelve years of progress?
Wolf OT., Brain Res. 1293(), 2009
PMID: 19376098
Cortisol and memory retrieval in humans: influence of emotional valence
Wolf, Ann. N.Y. Acad. Sci. 1032(), 2004
The relationship between stress induced cortisol levels and memory differs between men and women.
Wolf OT, Schommer NC, Hellhammer DH, McEwen BS, Kirschbaum C., Psychoneuroendocrinology 26(7), 2001
PMID: 11500252

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

PMID: 22688258
PubMed | Europe PMC

Suchen in

Google Scholar