The hybrid histidine kinase Slr1759 of the cyanobacterium Synechocystis sp. PCC 6803 contains FAD at its PAS domain
Michel K-P, Schröder A-K, Zimmermann M, Brandt S, Pistorius EK, Frankenberg-Dinkel N, Staiger D (2009)
Archives of Microbiology 191(6): 553-559.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
Autor*in
Michel, Klaus-Peter;
Schröder, Ann-Kristin;
Zimmermann, Maike;
Brandt, Sonja;
Pistorius, Elfriede K.;
Frankenberg-Dinkel, Nicole;
Staiger, DorotheeUniBi
Einrichtung
Abstract / Bemerkung
The cyanobacterium Synechocystis sp. PCC 6803 harbours 47 histidine kinases (Hiks). Among these are hybrid histidine kinases with one or two response regulator domains as well as numerous Hiks with several sensory domains. One example is the hybrid histidine kinase Slr1759 (Hik14) that has two PAS domains arranged in tandem linked to a predicted GAF domain. Here, we show that a Slr1759 derivative recombinantly expressed in Escherichia coli has a flavin cofactor. Using truncated Slr1759 variants, it is shown that the flavin associates with the first PAS domain. The cofactor reconstitutes the activity of d -amino acid oxidase apoprotein from pig kidney, indicating that the flavin derivative is FAD. Furthermore, the Slr1759 histidine kinase domain indeed undergoes autophosphorylation in vitro. The phosphorylated product of a recombinant Slr1759 derivative is sensitive to acids, pointing to a histidine residue as the phosphate-accepting group.
Stichworte
Synechocystis FAD Hybrid histidine kinase PAS domain
Erscheinungsjahr
2009
Zeitschriftentitel
Archives of Microbiology
Band
191
Ausgabe
6
Seite(n)
553-559
ISSN
0302-8933
eISSN
1432-072X
Page URI
https://pub.uni-bielefeld.de/record/2438873
Zitieren
Michel K-P, Schröder A-K, Zimmermann M, et al. The hybrid histidine kinase Slr1759 of the cyanobacterium Synechocystis sp. PCC 6803 contains FAD at its PAS domain. Archives of Microbiology. 2009;191(6):553-559.
Michel, K. - P., Schröder, A. - K., Zimmermann, M., Brandt, S., Pistorius, E. K., Frankenberg-Dinkel, N., & Staiger, D. (2009). The hybrid histidine kinase Slr1759 of the cyanobacterium Synechocystis sp. PCC 6803 contains FAD at its PAS domain. Archives of Microbiology, 191(6), 553-559. https://doi.org/10.1007/s00203-009-0483-x
Michel, Klaus-Peter, Schröder, Ann-Kristin, Zimmermann, Maike, Brandt, Sonja, Pistorius, Elfriede K., Frankenberg-Dinkel, Nicole, and Staiger, Dorothee. 2009. “The hybrid histidine kinase Slr1759 of the cyanobacterium Synechocystis sp. PCC 6803 contains FAD at its PAS domain”. Archives of Microbiology 191 (6): 553-559.
Michel, K. - P., Schröder, A. - K., Zimmermann, M., Brandt, S., Pistorius, E. K., Frankenberg-Dinkel, N., and Staiger, D. (2009). The hybrid histidine kinase Slr1759 of the cyanobacterium Synechocystis sp. PCC 6803 contains FAD at its PAS domain. Archives of Microbiology 191, 553-559.
Michel, K.-P., et al., 2009. The hybrid histidine kinase Slr1759 of the cyanobacterium Synechocystis sp. PCC 6803 contains FAD at its PAS domain. Archives of Microbiology, 191(6), p 553-559.
K.-P. Michel, et al., “The hybrid histidine kinase Slr1759 of the cyanobacterium Synechocystis sp. PCC 6803 contains FAD at its PAS domain”, Archives of Microbiology, vol. 191, 2009, pp. 553-559.
Michel, K.-P., Schröder, A.-K., Zimmermann, M., Brandt, S., Pistorius, E.K., Frankenberg-Dinkel, N., Staiger, D.: The hybrid histidine kinase Slr1759 of the cyanobacterium Synechocystis sp. PCC 6803 contains FAD at its PAS domain. Archives of Microbiology. 191, 553-559 (2009).
Michel, Klaus-Peter, Schröder, Ann-Kristin, Zimmermann, Maike, Brandt, Sonja, Pistorius, Elfriede K., Frankenberg-Dinkel, Nicole, and Staiger, Dorothee. “The hybrid histidine kinase Slr1759 of the cyanobacterium Synechocystis sp. PCC 6803 contains FAD at its PAS domain”. Archives of Microbiology 191.6 (2009): 553-559.
Alle Dateien verfügbar unter der/den folgenden Lizenz(en):
Copyright Statement:
Dieses Objekt ist durch das Urheberrecht und/oder verwandte Schutzrechte geschützt. [...]
Volltext(e)
Access Level
Open Access
Zuletzt Hochgeladen
2019-09-06T08:57:59Z
MD5 Prüfsumme
b5be950078cf83e24daeaafaaf6e769d
31 References
Daten bereitgestellt von Europe PubMed Central.
A study on apoenzyme from Rhodotorula gracilis D-amino acid oxidase.
Casalin P, Pollegioni L, Curti B, Pilone Simonetta M., Eur. J. Biochem. 197(2), 1991
PMID: 1673927
Casalin P, Pollegioni L, Curti B, Pilone Simonetta M., Eur. J. Biochem. 197(2), 1991
PMID: 1673927
The two-component system. Regulation of diverse signaling pathways in prokaryotes and eukaryotes.
Chang C, Stewart RC., Plant Physiol. 117(3), 1998
PMID: 9662515
Chang C, Stewart RC., Plant Physiol. 117(3), 1998
PMID: 9662515
GA, Proc Natl Acad Sci USA 98(), 2001
Bacterial response regulators: versatile regulatory strategies from common domains.
Gao R, Mack TR, Stock AM., Trends Biochem. Sci. 32(5), 2007
PMID: 17433693
Gao R, Mack TR, Stock AM., Trends Biochem. Sci. 32(5), 2007
PMID: 17433693
The PAS fold. A redefinition of the PAS domain based upon structural prediction.
Hefti MH, Francoijs KJ, de Vries SC, Dixon R, Vervoort J., Eur. J. Biochem. 271(6), 2004
PMID: 15009198
Hefti MH, Francoijs KJ, de Vries SC, Dixon R, Vervoort J., Eur. J. Biochem. 271(6), 2004
PMID: 15009198
Characterization of a two-component signal transduction system involved in the induction of alkaline phosphatase under phosphate-limiting conditions in Synechocystis sp. PCC 6803.
Hirani TA, Suzuki I, Murata N, Hayashi H, Eaton-Rye JJ., Plant Mol. Biol. 45(2), 2001
PMID: 11289505
Hirani TA, Suzuki I, Murata N, Hayashi H, Eaton-Rye JJ., Plant Mol. Biol. 45(2), 2001
PMID: 11289505
Cyanobacteriochromes: a new superfamily of tetrapyrrole-binding photoreceptors in cyanobacteria.
Ikeuchi M, Ishizuka T., Photochem. Photobiol. Sci. 7(10), 2008
PMID: 18846279
Ikeuchi M, Ishizuka T., Photochem. Photobiol. Sci. 7(10), 2008
PMID: 18846279
Structure of the redox sensor domain of Azotobacter vinelandii NifL at atomic resolution: signaling, dimerization, and mechanism.
Key J, Hefti M, Purcell EB, Moffat K., Biochemistry 46(12), 2007
PMID: 17319691
Key J, Hefti M, Purcell EB, Moffat K., Biochemistry 46(12), 2007
PMID: 17319691
Class II DNA photolyase from Arabidopsis thaliana contains FAD as a cofactor.
Kleiner O, Butenandt J, Carell T, Batschauer A., Eur. J. Biochem. 264(1), 1999
PMID: 10447684
Kleiner O, Butenandt J, Carell T, Batschauer A., Eur. J. Biochem. 264(1), 1999
PMID: 10447684
A two-component signal transduction system involved in nickel sensing in the cyanobacterium Synechocystis sp. PCC 6803.
Lopez-Maury L, Garcia-Dominguez M, Florencio FJ, Reyes JC., Mol. Microbiol. 43(1), 2002
PMID: 11849552
Lopez-Maury L, Garcia-Dominguez M, Florencio FJ, Reyes JC., Mol. Microbiol. 43(1), 2002
PMID: 11849552
K, Proc Natl Acad Sci USA 100(), 2003
GAF domains: two-billion-year-old molecular switches that bind cyclic nucleotides.
Martinez SE, Beavo JA, Hol WG., Mol. Interv. 2(5), 2002
PMID: 14993386
Martinez SE, Beavo JA, Hol WG., Mol. Interv. 2(5), 2002
PMID: 14993386
Stimulus perception in bacterial signal-transducing histidine kinases.
Mascher T, Helmann JD, Unden G., Microbiol. Mol. Biol. Rev. 70(4), 2006
PMID: 17158704
Mascher T, Helmann JD, Unden G., Microbiol. Mol. Biol. Rev. 70(4), 2006
PMID: 17158704
Purification and characterization of the Myxococcus xanthus FrzE protein shows that it has autophosphorylation activity.
McCleary WR, Zusman DR., J. Bacteriol. 172(12), 1990
PMID: 2123853
McCleary WR, Zusman DR., J. Bacteriol. 172(12), 1990
PMID: 2123853
The histidine kinase Hik33 perceives osmotic stress and cold stress in Synechocystis sp PCC 6803.
Mikami K, Kanesaki Y, Suzuki I, Murata N., Mol. Microbiol. 46(4), 2002
PMID: 12421299
Mikami K, Kanesaki Y, Suzuki I, Murata N., Mol. Microbiol. 46(4), 2002
PMID: 12421299
Compilation of all genes encoding bacterial two-component signal transducers in the genome of the cyanobacterium, Synechocystis sp. strain PCC 6803.
Mizuno T, Kaneko T, Tabata S., DNA Res. 3(6), 1996
PMID: 9097043
Mizuno T, Kaneko T, Tabata S., DNA Res. 3(6), 1996
PMID: 9097043
Exploitation of genomic sequences in a systematic analysis to access how cyanobacteria sense environmental stress.
Murata N, Suzuki I., J. Exp. Bot. 57(2), 2005
PMID: 16317040
Murata N, Suzuki I., J. Exp. Bot. 57(2), 2005
PMID: 16317040
T, Proc Natl Acad Sci USA 97(), 2000
A, J Biosci 61c(), 2006
A two-component signal transduction pathway regulates manganese homeostasis in Synechocystis 6803, a photosynthetic organism.
Ogawa T, Bao DH, Katoh H, Shibata M, Pakrasi HB, Bhattacharyya-Pakrasi M., J. Biol. Chem. 277(32), 2002
PMID: 12039966
Ogawa T, Bao DH, Katoh H, Shibata M, Pakrasi HB, Bhattacharyya-Pakrasi M., J. Biol. Chem. 277(32), 2002
PMID: 12039966
AUTHOR UNKNOWN, 0
J, 1989
Cyanobacterial hybrid kinase Sll0043 regulates phototaxis by suppressing pilin and twitching motility protein.
Shin BJ, Oh J, Kang S, Chung YH, Park YM, Kim YH, Kim S, Bhak J, Choi JS., J. Microbiol. 46(3), 2008
PMID: 18604500
Shin BJ, Oh J, Kang S, Chung YH, Park YM, Kim YH, Kim S, Bhak J, Choi JS., J. Microbiol. 46(3), 2008
PMID: 18604500
The pathway for perception and transduction of low-temperature signals in Synechocystis.
Suzuki I, Los DA, Kanesaki Y, Mikami K, Murata N., EMBO J. 19(6), 2000
PMID: 10716932
Suzuki I, Los DA, Kanesaki Y, Mikami K, Murata N., EMBO J. 19(6), 2000
PMID: 10716932
Cold-regulated genes under control of the cold sensor Hik33 in Synechocystis.
Suzuki I, Kanesaki Y, Mikami K, Kanehisa M, Murata N., Mol. Microbiol. 40(1), 2001
PMID: 11298290
Suzuki I, Kanesaki Y, Mikami K, Kanehisa M, Murata N., Mol. Microbiol. 40(1), 2001
PMID: 11298290
Biochemical and spectroscopic characterization of the bacterial phytochrome of Pseudomonas aeruginosa.
Tasler R, Moises T, Frankenberg-Dinkel N., FEBS J. 272(8), 2005
PMID: 15819886
Tasler R, Moises T, Frankenberg-Dinkel N., FEBS J. 272(8), 2005
PMID: 15819886
Aer on the inside looking out: paradigm for a PAS-HAMP role in sensing oxygen, redox and energy.
Taylor BL., Mol. Microbiol. 65(6), 2007
PMID: 17824925
Taylor BL., Mol. Microbiol. 65(6), 2007
PMID: 17824925
PAS domains: internal sensors of oxygen, redox potential, and light.
Taylor BL, Zhulin IB., Microbiol. Mol. Biol. Rev. 63(2), 1999
PMID: 10357859
Taylor BL, Zhulin IB., Microbiol. Mol. Biol. Rev. 63(2), 1999
PMID: 10357859
Histidine kinases and response regulator proteins in two-component signaling systems.
West AH, Stock AM., Trends Biochem. Sci. 26(6), 2001
PMID: 11406410
West AH, Stock AM., Trends Biochem. Sci. 26(6), 2001
PMID: 11406410
A two-component Mn2+-sensing system negatively regulates expression of the mntCAB operon in Synechocystis.
Yamaguchi K, Suzuki I, Yamamoto H, Lyukevich A, Bodrova I, Los DA, Piven I, Zinchenko V, Kanehisa M, Murata N., Plant Cell 14(11), 2002
PMID: 12417709
Yamaguchi K, Suzuki I, Yamamoto H, Lyukevich A, Bodrova I, Los DA, Piven I, Zinchenko V, Kanehisa M, Murata N., Plant Cell 14(11), 2002
PMID: 12417709
Correlation of PAS domains with electron transport-associated proteins in completely sequenced microbial genomes.
Zhulin IB, Taylor BL., Mol. Microbiol. 29(6), 1998
PMID: 9781888
Zhulin IB, Taylor BL., Mol. Microbiol. 29(6), 1998
PMID: 9781888
Export
Markieren/ Markierung löschen
Markierte Publikationen
Web of Science
Dieser Datensatz im Web of Science®Quellen
PMID: 19424679
PubMed | Europe PMC
Suchen in
Google Scholar