Quantitative Petri Net Model of Gene Regulated Metabolic Networks in the Cell

Chen M, Hofestädt R (2003)
In Silico Biology 3(3): 347-365.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Abstract / Bemerkung
A method to exploit hybrid Petri nets (HPN) for quantitatively modeling and simulating gene regulated metabolic networks is demonstrated. A global kinetic modeling strategy and Petri net modeling algorithm are applied to perform the bioprocess functioning and model analysis. With the model, the interrelations between pathway analysis and metabolic control mechanism are outlined. Diagrammatical results of the dynamics of metabolites are simulated and observed by implementing a HPN tool, Visual Object Net ++. An explanation of the observed behavior of the urea cycle is proposed to indicate possibilities for metabolic engineering and medical care. Finally, the perspective of Petri nets on modeling and simulation of metabolic networks is discussed.
Erscheinungsjahr
2003
Zeitschriftentitel
In Silico Biology
Band
3
Ausgabe
3
Seite(n)
347-365
ISSN
1386-6338
Page URI
https://pub.uni-bielefeld.de/record/2378667

Zitieren

Chen M, Hofestädt R. Quantitative Petri Net Model of Gene Regulated Metabolic Networks in the Cell. In Silico Biology. 2003;3(3):347-365.
Chen, M., & Hofestädt, R. (2003). Quantitative Petri Net Model of Gene Regulated Metabolic Networks in the Cell. In Silico Biology, 3(3), 347-365.
Chen, M., and Hofestädt, R. (2003). Quantitative Petri Net Model of Gene Regulated Metabolic Networks in the Cell. In Silico Biology 3, 347-365.
Chen, M., & Hofestädt, R., 2003. Quantitative Petri Net Model of Gene Regulated Metabolic Networks in the Cell. In Silico Biology, 3(3), p 347-365.
M. Chen and R. Hofestädt, “Quantitative Petri Net Model of Gene Regulated Metabolic Networks in the Cell”, In Silico Biology, vol. 3, 2003, pp. 347-365.
Chen, M., Hofestädt, R.: Quantitative Petri Net Model of Gene Regulated Metabolic Networks in the Cell. In Silico Biology. 3, 347-365 (2003).
Chen, Ming, and Hofestädt, Ralf. “Quantitative Petri Net Model of Gene Regulated Metabolic Networks in the Cell”. In Silico Biology 3.3 (2003): 347-365.

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Quellen

PMID: 21685563
PubMed | Europe PMC

Suchen in

Google Scholar