A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function

Antonin W, Holroyd C, Fasshauer D, Pabst S, Fischer von Mollard G, Jahn R (2000)
EMBO JOURNAL 19(23): 6453-6464.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Antonin, W; Holroyd, C; Fasshauer, D; Pabst, S; Fischer von Mollard, GabrieleUniBi ; Jahn, R
Abstract / Bemerkung
Sets of SNARE proteins mediate membrane fusion by assembling into core complexes. Multiple SNAREs are thought to function in different intracellular trafficking steps but it is often unclear which of the SNAREs cooperate in individual fusion reactions. We report that syntaxin 7, syntasin 8, vti1b and endobrevin/ VAMP-8 form a complex that functions in the fusion of late endosomes. Antibodies specific for each protein coprecipitate the complex, inhibit homotypic fusion of late endosomes in vitro and retard delivery of endocytosed epidermal growth factor to lysosomes. The purified proteins form core complexes with biochemical and biophysical properties remarkably similar to the neuronal core complex, although each of the four proteins carries a transmembrane domain and three have independently folded N-terminal domains. Substitution experiments, sequence and structural comparisons revealed that each protein occupies a unique position in the complex, with syntaxin 7 corresponding to syntasin 1, and vti1b and syntaxin 8 corresponding to the N- and C-terminal domains of SNAP-25, respectively. We conclude that the structure of core complexes and their molecular mechanism in membrane fusion is highly conserved between distant SNAREs.
Erscheinungsjahr
2000
Zeitschriftentitel
EMBO JOURNAL
Band
19
Ausgabe
23
Seite(n)
6453-6464
ISSN
0261-4189
eISSN
1460-2075
Page URI
https://pub.uni-bielefeld.de/record/2374336

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Antonin W, Holroyd C, Fasshauer D, Pabst S, Fischer von Mollard G, Jahn R. A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. EMBO JOURNAL. 2000;19(23):6453-6464.
Antonin, W., Holroyd, C., Fasshauer, D., Pabst, S., Fischer von Mollard, G., & Jahn, R. (2000). A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. EMBO JOURNAL, 19(23), 6453-6464. https://doi.org/10.1093/emboj/19.23.6453
Antonin, W, Holroyd, C, Fasshauer, D, Pabst, S, Fischer von Mollard, Gabriele, and Jahn, R. 2000. “A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function”. EMBO JOURNAL 19 (23): 6453-6464.
Antonin, W., Holroyd, C., Fasshauer, D., Pabst, S., Fischer von Mollard, G., and Jahn, R. (2000). A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. EMBO JOURNAL 19, 6453-6464.
Antonin, W., et al., 2000. A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. EMBO JOURNAL, 19(23), p 6453-6464.
W. Antonin, et al., “A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function”, EMBO JOURNAL, vol. 19, 2000, pp. 6453-6464.
Antonin, W., Holroyd, C., Fasshauer, D., Pabst, S., Fischer von Mollard, G., Jahn, R.: A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. EMBO JOURNAL. 19, 6453-6464 (2000).
Antonin, W, Holroyd, C, Fasshauer, D, Pabst, S, Fischer von Mollard, Gabriele, and Jahn, R. “A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function”. EMBO JOURNAL 19.23 (2000): 6453-6464.

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Daten bereitgestellt von Europe PubMed Central.

Endosomal and Phagosomal SNAREs.
Dingjan I, Linders PTA, Verboogen DRJ, Revelo NH, Ter Beest M, van den Bogaart G., Physiol Rev 98(3), 2018
PMID: 29790818
Sphingolipid metabolism - an ambiguous regulator of autophagy in the brain.
van Echten-Deckert G, Alam S., Biol Chem 399(8), 2018
PMID: 29908127
Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi.
Emperador-Melero J, Huson V, van Weering J, Bollmann C, Fischer von Mollard G, Toonen RF, Verhage M., Nat Commun 9(1), 2018
PMID: 30143604
Salmonella SipA mimics a cognate SNARE for host Syntaxin8 to promote fusion with early endosomes.
Singh PK, Kapoor A, Lomash RM, Kumar K, Kamerkar SC, Pucadyil TJ, Mukhopadhyay A., J Cell Biol (), 2018
PMID: 30309979
SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages.
Shi B, Huang QQ, Birkett R, Doyle R, Dorfleutner A, Stehlik C, He C, Pope RM., Autophagy 13(2), 2017
PMID: 27929705
Two-Pore Channels: Catalyzers of Endolysosomal Transport and Function.
Grimm C, Chen CC, Wahl-Schott C, Biel M., Front Pharmacol 8(), 2017
PMID: 28223936
Oxidized phagosomal NOX2 complex is replenished from lysosomes.
Dingjan I, Linders PT, van den Bekerom L, Baranov MV, Halder P, Ter Beest M, van den Bogaart G., J Cell Sci 130(7), 2017
PMID: 28202687
Phosphorylated Presenilin 1 decreases β-amyloid by facilitating autophagosome-lysosome fusion.
Bustos V, Pulina MV, Bispo A, Lam A, Flajolet M, Gorelick FS, Greengard P., Proc Natl Acad Sci U S A 114(27), 2017
PMID: 28533369
Phagocytosis: A Fundamental Process in Immunity.
Rosales C, Uribe-Querol E., Biomed Res Int 2017(), 2017
PMID: 28691037
Roles of Cellular NSF Protein in Entry and Nuclear Egress of Budded Virions of Autographa californica Multiple Nucleopolyhedrovirus.
Guo Y, Yue Q, Gao J, Wang Z, Chen YR, Blissard GW, Liu TX, Li Z., J Virol 91(20), 2017
PMID: 28747507
Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses.
He J, Johnson JL, Monfregola J, Ramadass M, Pestonjamasp K, Napolitano G, Zhang J, Catz SD., Mol Biol Cell 27(3), 2016
PMID: 26680738
A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly.
Schmidt FI, Lu A, Chen JW, Ruan J, Tang C, Wu H, Ploegh HL., J Exp Med 213(5), 2016
PMID: 27069117
Soybean Golgi SNARE 12 protein interacts with Soybean mosaic virus encoded P3N-PIPO protein.
Song P, Zhi H, Wu B, Cui X, Chen X., Biochem Biophys Res Commun 478(4), 2016
PMID: 27553272
Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking.
Young MM, Takahashi Y, Fox TE, Yun JK, Kester M, Wang HG., Cell Rep 17(6), 2016
PMID: 27806293
VAMP8 facilitates cellular proliferation and temozolomide resistance in human glioma cells.
Chen Y, Meng D, Wang H, Sun R, Wang D, Wang S, Fan J, Zhao Y, Wang J, Yang S, Huai C, Song X, Qin R, Xu T, Yun D, Hu L, Yang J, Zhang X, Chen H, Chen J, Chen H, Lu D., Neuro Oncol 17(3), 2015
PMID: 25209430
Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability.
Golebiewska EM, Harper MT, Williams CM, Savage JS, Goggs R, Fischer von Mollard G, Poole AW., J Biol Chem 290(3), 2015
PMID: 25404741
Vacuole dynamics in the salivary glands of Drosophila melanogaster during prepupal development.
Farkaš R, Beňová-Liszeková D, Mentelová L, Mahmood S, Ďatková Z, Beňo M, Pečeňová L, Raška O, Šmigová J, Chase BA, Raška I, Mechler BM., Dev Growth Differ 57(1), 2015
PMID: 25611296
ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes.
Diao J, Liu R, Rong Y, Zhao M, Zhang J, Lai Y, Zhou Q, Wilz LM, Li J, Vivona S, Pfuetzner RA, Brunger AT, Zhong Q., Nature 520(7548), 2015
PMID: 25686604
VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity.
Marshall MR, Pattu V, Halimani M, Maier-Peuschel M, Müller ML, Becherer U, Hong W, Hoth M, Tschernig T, Bryceson YT, Rettig J., J Cell Biol 210(1), 2015
PMID: 26124288
Milk secretion: The role of SNARE proteins.
Truchet S, Chat S, Ollivier-Bousquet M., J Mammary Gland Biol Neoplasia 19(1), 2014
PMID: 24264376
The SNARE protein vti1a functions in dense-core vesicle biogenesis.
Walter AM, Kurps J, de Wit H, Schöning S, Toft-Bertelsen TL, Lauks J, Ziomkiewicz I, Weiss AN, Schulz A, Fischer von Mollard G, Verhage M, Sørensen JB., EMBO J 33(15), 2014
PMID: 24902738
Wheat TaNPSN SNARE homologues are involved in vesicle-mediated resistance to stripe rust (Puccinia striiformis f. sp. tritici).
Wang X, Wang X, Deng L, Chang H, Dubcovsky J, Feng H, Han Q, Huang L, Kang Z., J Exp Bot 65(17), 2014
PMID: 24963004
High susceptibility to fatty liver disease in two-pore channel 2-deficient mice.
Grimm C, Holdt LM, Chen CC, Hassan S, Müller C, Jörs S, Cuny H, Kissing S, Schröder B, Butz E, Northoff B, Castonguay J, Luber CA, Moser M, Spahn S, Lüllmann-Rauch R, Fendel C, Klugbauer N, Griesbeck O, Haas A, Mann M, Bracher F, Teupser D, Saftig P, Biel M, Wahl-Schott C., Nat Commun 5(), 2014
PMID: 25144390
The biogenesis of lysosomes and lysosome-related organelles.
Luzio JP, Hackmann Y, Dieckmann NM, Griffiths GM., Cold Spring Harb Perspect Biol 6(9), 2014
PMID: 25183830
Molecular characterization and functional significance of the Vti family of SNARE proteins in tick salivary glands.
Villarreal AM, Adamson SW, Browning RE, Budachetri K, Sajid MS, Karim S., Insect Biochem Mol Biol 43(5), 2013
PMID: 23499931
Vesicle-associated membrane protein 4 and syntaxin 6 interactions at the chlamydial inclusion.
Kabeiseman EJ, Cichos K, Hackstadt T, Lucas A, Moore ER., Infect Immun 81(9), 2013
PMID: 23798538
Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins.
Yu H, Rathore SS, Lopez JA, Davis EM, James DE, Martin JL, Shen J., Proc Natl Acad Sci U S A 110(35), 2013
PMID: 23918365
Vti1a identifies a vesicle pool that preferentially recycles at rest and maintains spontaneous neurotransmission.
Ramirez DM, Khvotchev M, Trauterman B, Kavalali ET., Neuron 73(1), 2012
PMID: 22243751
The synaptic vesicle SNARE neuronal Synaptobrevin promotes endolysosomal degradation and prevents neurodegeneration.
Haberman A, Williamson WR, Epstein D, Wang D, Rina S, Meinertzhagen IA, Hiesinger PR., J Cell Biol 196(2), 2012
PMID: 22270918
VAMP8/endobrevin is a critical factor for the homotypic granule growth in pancreatic acinar cells.
Hammel I, Wang CC, Hong W, Amihai D., Cell Tissue Res 348(3), 2012
PMID: 22450911
Rab GTPases regulating receptor trafficking at the late endosome-lysosome membranes.
Ng EL, Gan BQ, Ng F, Tang BL., Cell Biochem Funct 30(6), 2012
PMID: 22473705
Regulated exocytosis in chromaffin cells and cytotoxic T lymphocytes: how similar are they?
Becherer U, Medart MR, Schirra C, Krause E, Stevens D, Rettig J., Cell Calcium 52(3-4), 2012
PMID: 22560267
Dual role of VAMP8 in regulating insulin exocytosis and islet β cell growth.
Zhu D, Zhang Y, Lam PP, Dolai S, Liu Y, Cai EP, Choi D, Schroer SA, Kang Y, Allister EM, Qin T, Wheeler MB, Wang CC, Hong WJ, Woo M, Gaisano HY., Cell Metab 16(2), 2012
PMID: 22841572
Defective HIV-1 particle assembly in AP-3-deficient cells derived from patients with Hermansky-Pudlak syndrome type 2.
Liu L, Sutton J, Woodruff E, Villalta F, Spearman P, Dong X., J Virol 86(20), 2012
PMID: 22875976
The sorting receptor Sortilin exhibits a dual function in exocytic trafficking of interferon-γ and granzyme A in T cells.
Herda S, Raczkowski F, Mittrücker HW, Willimsky G, Gerlach K, Kühl AA, Breiderhoff T, Willnow TE, Dörken B, Höpken UE, Rehm A., Immunity 37(5), 2012
PMID: 23084031
The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation.
Schäfer IB, Hesketh GG, Bright NA, Gray SR, Pryor PR, Evans PR, Luzio JP, Owen DJ., Nat Struct Mol Biol 19(12), 2012
PMID: 23104059
Enhanced energy expenditure, glucose utilization, and insulin sensitivity in VAMP8 null mice.
Zong H, Wang CC, Vaitheesvaran B, Kurland IJ, Hong W, Pessin JE., Diabetes 60(1), 2011
PMID: 20876717
Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development.
Kunwar AJ, Rickmann M, Backofen B, Browski SM, Rosenbusch J, Schöning S, Fleischmann T, Krieglstein K, Fischer von Mollard G., Proc Natl Acad Sci U S A 108(6), 2011
PMID: 21262811
Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages.
Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL, Murray RZ., Traffic 12(6), 2011
PMID: 21388490
Syntaxin7 is required for lytic granule release from cytotoxic T lymphocytes.
Pattu V, Qu B, Marshall M, Becherer U, Junker C, Matti U, Schwarz EC, Krause E, Hoth M, Rettig J., Traffic 12(7), 2011
PMID: 21438968
Topological arrangement of the intracellular membrane fusion machinery.
Rathore SS, Ghosh N, Ouyang Y, Shen J., Mol Biol Cell 22(14), 2011
PMID: 21633111
Epsin N-terminal homology domains bind on opposite sides of two SNAREs.
Wang J, Gossing M, Fang P, Zimmermann J, Li X, von Mollard GF, Niu L, Teng M., Proc Natl Acad Sci U S A 108(30), 2011
PMID: 21746902
A role for VAMP8/endobrevin in surface deployment of the water channel aquaporin 2.
Wang CC, Ng CP, Shi H, Liew HC, Guo K, Zeng Q, Hong W., Mol Cell Biol 30(1), 2010
PMID: 19841070
Mig-6 controls EGFR trafficking and suppresses gliomagenesis.
Ying H, Zheng H, Scott K, Wiedemeyer R, Yan H, Lim C, Huang J, Dhakal S, Ivanova E, Xiao Y, Zhang H, Hu J, Stommel JM, Lee MA, Chen AJ, Paik JH, Segatto O, Brennan C, Elferink LA, Wang YA, Chin L, DePinho RA., Proc Natl Acad Sci U S A 107(15), 2010
PMID: 20351267
Cell-free fusion of bacteria-containing phagosomes with endocytic compartments.
Becken U, Jeschke A, Veltman K, Haas A., Proc Natl Acad Sci U S A 107(48), 2010
PMID: 21071675
Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex.
Rathore SS, Bend EG, Yu H, Hammarlund M, Jorgensen EM, Shen J., Proc Natl Acad Sci U S A 107(52), 2010
PMID: 21139055
SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery.
Zhu GD, Salazar G, Zlatic SA, Fiza B, Doucette MM, Heilman CJ, Levey AI, Faundez V, L'hernault SW., Mol Biol Cell 20(4), 2009
PMID: 19109425
Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles.
Newell-Litwa K, Salazar G, Smith Y, Faundez V., Mol Biol Cell 20(5), 2009
PMID: 19144828
Antimicrobial mechanisms of phagocytes and bacterial evasion strategies.
Flannagan RS, Cosío G, Grinstein S., Nat Rev Microbiol 7(5), 2009
PMID: 19369951
Helical extension of the neuronal SNARE complex into the membrane.
Stein A, Weber G, Wahl MC, Jahn R., Nature 460(7254), 2009
PMID: 19571812
Transcriptome analysis of the central nervous system of the mollusc Lymnaea stagnalis.
Feng ZP, Zhang Z, van Kesteren RE, Straub VA, van Nierop P, Jin K, Nejatbakhsh N, Goldberg JI, Spencer GE, Yeoman MS, Wildering W, Coorssen JR, Croll RP, Buck LT, Syed NI, Smit AB., BMC Genomics 10(), 2009
PMID: 19775440
Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking.
Chaineau M, Danglot L, Galli T., FEBS Lett 583(23), 2009
PMID: 19837067
Syntaxin 8 has two functionally distinct di-leucine-based motifs.
Kasai K, Suga K, Izumi T, Akagawa K., Cell Mol Biol Lett 13(1), 2008
PMID: 17965969
Cloning and characterization of three genes encoding Qb-SNARE proteins in rice.
Bao YM, Wang JF, Huang J, Zhang HS., Mol Genet Genomics 279(3), 2008
PMID: 18197419
Interactions between neuronal fusion proteins explored by molecular dynamics.
Durrieu MP, Lavery R, Baaden M., Biophys J 94(9), 2008
PMID: 18212009
SNARE protein mimicry by an intracellular bacterium.
Delevoye C, Nilges M, Dehoux P, Paumet F, Perrinet S, Dautry-Varsat A, Subtil A., PLoS Pathog 4(3), 2008
PMID: 18369472
Involvement of vesicle-associated membrane protein 7 in human gastric epithelial cell vacuolation induced by Helicobacter pylori-produced VacA.
Mashima H, Suzuki J, Hirayama T, Yoshikumi Y, Ohno H, Ohnishi H, Yasuda H, Fujita T, Omata M., Infect Immun 76(6), 2008
PMID: 18362137
Endosomal SNARE proteins regulate CFTR activity and trafficking in epithelial cells.
Bilan F, Nacfer M, Fresquet F, Norez C, Melin P, Martin-Berge A, Costa de Beauregard MA, Becq F, Kitzis A, Thoreau V., Exp Cell Res 314(11-12), 2008
PMID: 18570918
A role for soluble N-ethylmaleimide-sensitive factor attachment protein receptor complex dimerization during neurosecretion.
Fdez E, Jowitt TA, Wang MC, Rajebhosale M, Foster K, Bella J, Baldock C, Woodman PG, Hilfiker S., Mol Biol Cell 19(8), 2008
PMID: 18508917
SNAREing the basis of multicellularity: consequences of protein family expansion during evolution.
Kloepper TH, Kienle CN, Fasshauer D., Mol Biol Evol 25(9), 2008
PMID: 18621745
Regulation of the endosomal SNARE protein syntaxin 7 by colony-stimulating factor 1 in macrophages.
Achuthan A, Masendycz P, Lopez JA, Nguyen T, James DE, Sweet MJ, Hamilton JA, Scholz GM., Mol Cell Biol 28(20), 2008
PMID: 18710945
Members of a mammalian SNARE complex interact in the endoplasmic reticulum in vivo and are found in COPI vesicles.
Verrier SE, Willmann M, Wenzel D, Winter U, von Mollard GF, Söling HD., Eur J Cell Biol 87(11), 2008
PMID: 18834646
Thymic alterations in mice deficient for the SNARE protein VAMP8/endobrevin.
Kanwar N, Fayyazi A, Backofen B, Nitsche M, Dressel R, von Mollard GF., Cell Tissue Res 334(2), 2008
PMID: 18923845
Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction.
Ren Q, Barber HK, Crawford GL, Karim ZA, Zhao C, Choi W, Wang CC, Hong W, Whiteheart SW., Mol Biol Cell 18(1), 2007
PMID: 17065550
Protein kinase D 3 is localized in vesicular structures and interacts with vesicle-associated membrane protein 2.
Lu G, Chen J, Espinoza LA, Garfield S, Toshiyuki S, Akiko H, Huppler A, Wang QJ., Cell Signal 19(4), 2007
PMID: 17196367
Early endosomal SNAREs form a structurally conserved SNARE complex and fuse liposomes with multiple topologies.
Zwilling D, Cypionka A, Pohl WH, Fasshauer D, Walla PJ, Wahl MC, Jahn R., EMBO J 26(1), 2007
PMID: 17159904
Selective activation of cognate SNAREpins by Sec1/Munc18 proteins.
Shen J, Tareste DC, Paumet F, Rothman JE, Melia TJ., Cell 128(1), 2007
PMID: 17218264
Divergent functions of VTI12 and VTI11 in trafficking to storage and lytic vacuoles in Arabidopsis.
Sanmartín M, Ordóñez A, Sohn EJ, Robert S, Sánchez-Serrano JJ, Surpin MA, Raikhel NV, Rojo E., Proc Natl Acad Sci U S A 104(9), 2007
PMID: 17360696
Dysfunction of Golgi tethers, SNAREs, and SNAPs in monocrotaline-induced pulmonary hypertension.
Sehgal PB, Mukhopadhyay S, Xu F, Patel K, Shah M., Am J Physiol Lung Cell Mol Physiol 292(6), 2007
PMID: 17337506
Lysosomes: fusion and function.
Luzio JP, Pryor PR, Bright NA., Nat Rev Mol Cell Biol 8(8), 2007
PMID: 17637737
T cells use two directionally distinct pathways for cytokine secretion.
Huse M, Lillemeier BF, Kuhns MS, Chen DS, Davis MM., Nat Immunol 7(3), 2006
PMID: 16444260
Homotypic fusion of early endosomes: SNAREs do not determine fusion specificity.
Brandhorst D, Zwilling D, Rizzoli SO, Lippert U, Lang T, Jahn R., Proc Natl Acad Sci U S A 103(8), 2006
PMID: 16469845
Involvement of syntaxin 18, an endoplasmic reticulum (ER)-localized SNARE protein, in ER-mediated phagocytosis.
Hatsuzawa K, Tamura T, Hashimoto H, Hashimoto H, Yokoya S, Miura M, Nagaya H, Wada I., Mol Biol Cell 17(9), 2006
PMID: 16790498
Extracting sequence motifs and the phylogenetic features of SNARE-dependent membrane traffic.
Yoshizawa AC, Kawashima S, Okuda S, Fujita M, Itoh M, Moriya Y, Hattori M, Kanehisa M., Traffic 7(8), 2006
PMID: 16882042
SNAREs--engines for membrane fusion.
Jahn R, Scheller RH., Nat Rev Mol Cell Biol 7(9), 2006
PMID: 16912714
Evidence for early endosome-like fusion of recently endocytosed synaptic vesicles.
Rizzoli SO, Bethani I, Zwilling D, Wenzel D, Siddiqui TJ, Brandhorst D, Jahn R., Traffic 7(9), 2006
PMID: 17004320
SNAREing immunity: the role of SNAREs in the immune system.
Stow JL, Manderson AP, Murray RZ., Nat Rev Immunol 6(12), 2006
PMID: 17124513
SNAREs and traffic.
Hong W., Biochim Biophys Acta 1744(2), 2005
PMID: 15893389
SNARE complexes and neuroexocytosis: how many, how close?
Montecucco C, Schiavo G, Pantano S., Trends Biochem Sci 30(7), 2005
PMID: 15935678
Trans-Golgi network syntaxin 10 functions distinctly from syntaxins 6 and 16.
Wang Y, Tai G, Lu L, Johannes L, Hong W, Tang BL., Mol Membr Biol 22(4), 2005
PMID: 16154903
Determinants of liposome fusion mediated by synaptic SNARE proteins.
Schuette CG, Hatsuzawa K, Margittai M, Stein A, Riedel D, Küster P, König M, Seidel C, Jahn R., Proc Natl Acad Sci U S A 101(9), 2004
PMID: 14981239
Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis.
Rao SK, Huynh C, Proux-Gillardeaux V, Galli T, Andrews NW., J Biol Chem 279(19), 2004
PMID: 14993220
Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events.
Pryor PR, Mullock BM, Bright NA, Lindsay MR, Gray SR, Richardson SC, Stewart A, James DE, Piper RC, Luzio JP., EMBO Rep 5(6), 2004
PMID: 15133481
A role of VAMP8/endobrevin in regulated exocytosis of pancreatic acinar cells.
Wang CC, Ng CP, Lu L, Atlashkin V, Zhang W, Seet LF, Hong W., Dev Cell 7(3), 2004
PMID: 15363411
D53 is a novel endosomal SNARE-binding protein that enhances interaction of syntaxin 1 with the synaptobrevin 2 complex in vitro.
Proux-Gillardeaux V, Galli T, Callebaut I, Mikhailik A, Calothy G, Marx M., Biochem J 370(pt 1), 2003
PMID: 12376003
Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain.
Hasegawa H, Zinsser S, Rhee Y, Vik-Mo EO, Davanger S, Hay JC., Mol Biol Cell 14(2), 2003
PMID: 12589064
Membrane fusion.
Jahn R, Lang T, Südhof TC., Cell 112(4), 2003
PMID: 12600315
The SNARE motif contributes to rbet1 intracellular targeting and dynamics independently of SNARE interactions.
Joglekar AP, Xu D, Rigotti DJ, Fairman R, Hay JC., J Biol Chem 278(16), 2003
PMID: 12566453
Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest.
Fratti RA, Chua J, Vergne I, Deretic V., Proc Natl Acad Sci U S A 100(9), 2003
PMID: 12702770
Phagosome maturation: a few bugs in the system.
Scott CC, Botelho RJ, Grinstein S., J Membr Biol 193(3), 2003
PMID: 12962275
A SNARE complex containing SGR3/AtVAM3 and ZIG/VTI11 in gravity-sensing cells is important for Arabidopsis shoot gravitropism.
Yano D, Sato M, Saito C, Sato MH, Morita MT, Tasaka M., Proc Natl Acad Sci U S A 100(14), 2003
PMID: 12815100
Transcytosis: crossing cellular barriers.
Tuma P, Hubbard AL., Physiol Rev 83(3), 2003
PMID: 12843411
The role of mVps18p in clustering, fusion, and intracellular localization of late endocytic organelles.
Poupon V, Stewart A, Gray SR, Piper RC, Luzio JP., Mol Biol Cell 14(10), 2003
PMID: 14517315
What is the role of SNARE proteins in membrane fusion?
Duman JG, Forte JG., Am J Physiol Cell Physiol 285(2), 2003
PMID: 12842832
Deletion of the SNARE vti1b in mice results in the loss of a single SNARE partner, syntaxin 8.
Atlashkin V, Kreykenbohm V, Eskelinen EL, Wenzel D, Fayyazi A, Fischer von Mollard G., Mol Cell Biol 23(15), 2003
PMID: 12861006
Structural insights into the SNARE mechanism.
Fasshauer D., Biochim Biophys Acta 1641(2-3), 2003
PMID: 12914950
Control of eukaryotic membrane fusion by N-terminal domains of SNARE proteins.
Dietrich LE, Boeddinghaus C, LaGrassa TJ, Ungermann C., Biochim Biophys Acta 1641(2-3), 2003
PMID: 12914952
Identification and characterization of Snapin as a ubiquitously expressed SNARE-binding protein that interacts with SNAP23 in non-neuronal cells.
Buxton P, Zhang XM, Walsh B, Sriratana A, Schenberg I, Manickam E, Rowe T., Biochem J 375(pt 2), 2003
PMID: 12877659
Cell vacuolization induced by Helicobacter pylori VacA cytotoxin does not depend on late endosomal SNAREs.
de Bernard M, Moschioni M, Habermann A, Griffiths G, Montecucco C., Cell Microbiol 4(1), 2002
PMID: 11856169
Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform.
Mallard F, Tang BL, Galli T, Tenza D, Saint-Pol A, Yue X, Antony C, Hong W, Goud B, Johannes L., J Cell Biol 156(4), 2002
PMID: 11839770
Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes.
Sachse M, Urbé S, Oorschot V, Strous GJ, Klumperman J., Mol Biol Cell 13(4), 2002
PMID: 11950941
Membrane fusion in eukaryotic cells.
Mayer A., Annu Rev Cell Dev Biol 18(), 2002
PMID: 12142286
NPSN11 is a cell plate-associated SNARE protein that interacts with the syntaxin KNOLLE.
Zheng H, Bednarek SY, Sanderfoot AA, Alonso J, Ecker JR, Raikhel NV., Plant Physiol 129(2), 2002
PMID: 12068098
Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog.
Misura KM, Bock JB, Gonzalez LC, Scheller RH, Weis WI., Proc Natl Acad Sci U S A 99(14), 2002
PMID: 12082176
Insights from yeast endosomes.
Pelham HR., Curr Opin Cell Biol 14(4), 2002
PMID: 12383796
Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules.
Riedel D, Antonin W, Fernandez-Chacon R, Alvarez de Toledo G, Jo T, Geppert M, Valentijn JA, Valentijn K, Jamieson JD, Südhof TC, Jahn R., Mol Cell Biol 22(18), 2002
PMID: 12192047
Phagosome maturation: aging gracefully.
Vieira OV, Botelho RJ, Grinstein S., Biochem J 366(pt 3), 2002
PMID: 12061891
Three SNARE complexes cooperate to mediate membrane fusion.
Hua Y, Scheller RH., Proc Natl Acad Sci U S A 98(14), 2001
PMID: 11427709
SNARE complex structure and function.
Hay JC., Exp Cell Res 271(1), 2001
PMID: 11697877
The Tlg SNARE complex is required for TGN homotypic fusion.
Brickner JH, Blanchette JM, Sipos G, Fuller RS., J Cell Biol 155(6), 2001
PMID: 11739408

53 References

Daten bereitgestellt von Europe PubMed Central.

SNARE interactions are not selective. Implications for membrane fusion specificity.
Yang B, Gonzalez L Jr, Prekeris R, Steegmaier M, Advani RJ, Scheller RH., J. Biol. Chem. 274(9), 1999
PMID: 10026182
Mixed and non-cognate SNARE complexes. Characterization of assembly and biophysical properties.
Fasshauer D, Antonin W, Margittai M, Pabst S, Jahn R., J. Biol. Chem. 274(22), 1999
PMID: 10336434
Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking.
Steegmaier M, Klumperman J, Foletti DL, Yoo JS, Scheller RH., Mol. Biol. Cell 10(6), 1999
PMID: 10359608
Three v-SNAREs and two t-SNAREs, present in a pentameric cis-SNARE complex on isolated vacuoles, are essential for homotypic fusion.
Ungermann C, von Mollard GF, Jensen ON, Margolis N, Stevens TH, Wickner W., J. Cell Biol. 145(7), 1999
PMID: 10385523
The plant vesicle-associated SNARE AtVTI1a likely mediates vesicle transport from the trans-Golgi network to the prevacuolar compartment.
Zheng H, von Mollard GF, Kovaleva V, Stevens TH, Raikhel NV., Mol. Biol. Cell 10(7), 1999
PMID: 10397763
Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13.
McBride HM, Rybin V, Murphy C, Giner A, Teasdale R, Zerial M., Cell 98(3), 1999
PMID: 10458612
VAMP-7 mediates vesicular transport from endosomes to lysosomes.
Advani RJ, Yang B, Prekeris R, Lee KC, Klumperman J, Scheller RH., J. Cell Biol. 146(4), 1999
PMID: 10459012
Fusion of endosomes involved in synaptic vesicle recycling.
Holroyd C, Kistner U, Annaert W, Jahn R., Mol. Biol. Cell 10(9), 1999
PMID: 10473644
The Rab5 effector EEA1 interacts directly with syntaxin-6.
Simonsen A, Gaullier JM, D'Arrigo A, Stenmark H., J. Biol. Chem. 274(41), 1999
PMID: 10506127
Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking.
Prekeris R, Yang B, Oorschot V, Klumperman J, Scheller RH., Mol. Biol. Cell 10(11), 1999
PMID: 10564279
The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cells.
Yoshimori T, Yamagata F, Yamamoto A, Mizushima N, Kabeya Y, Nara A, Miwako I, Ohashi M, Ohsumi M, Ohsumi Y., Mol. Biol. Cell 11(2), 2000
PMID: 10679028
Preferential association of syntaxin 8 with the early endosome.
Subramaniam VN, Loh E, Horstmann H, Habermann A, Xu Y, Coe J, Griffiths G, Hong W., J. Cell. Sci. 113 ( Pt 6)(), 2000
PMID: 10683148
Syntaxin 7 mediates endocytic trafficking to late endosomes.
Nakamura N, Yamamoto A, Wada Y, Futai M., J. Biol. Chem. 275(9), 2000
PMID: 10692457
Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex.
Misura KM, Scheller RH, Weis WI., Nature 404(6776), 2000
PMID: 10746715
Selective interaction of complexin with the neuronal SNARE complex. Determination of the binding regions.
Pabst S, Hazzard JW, Antonin W, Sudhof TC, Jahn R, Rizo J, Fasshauer D., J. Biol. Chem. 275(26), 2000
PMID: 10777504
Mechanisms of intracellular protein transport.
Rothman JE., Nature 372(6501), 1994
PMID: 7969419
Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes.
Prekeris R, Klumperman J, Chen YA, Scheller RH., J. Cell Biol. 143(4), 1998
PMID: 9817754
Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs.
Fasshauer D, Sutton RB, Brunger AT, Jahn R., Proc. Natl. Acad. Sci. U.S.A. 95(26), 1998
PMID: 9861047
Vesicle fusion from yeast to man.
Ferro-Novick S, Jahn R., Nature 370(6486), 1994
PMID: 8028665
Tetanus toxin-mediated cleavage of cellubrevin impairs exocytosis of transferrin receptor-containing vesicles in CHO cells.
Galli T, Chilcote T, Mundigl O, Binz T, Niemann H, De Camilli P., J. Cell Biol. 125(5), 1994
PMID: 8195285
Endocytosis and molecular sorting.
Mellman I., Annu. Rev. Cell Dev. Biol. 12(), 1996
PMID: 8970738
Protein transport. A fusion of new ideas.
Bock JB, Scheller RH., Nature 387(6629), 1997
PMID: 9144278
Ca2+-triggered peptide secretion in single cells imaged with green fluorescent protein and evanescent-wave microscopy.
Lang T, Wacker I, Steyer J, Kaether C, Wunderlich I, Soldati T, Gerdes HH, Almers W., Neuron 18(6), 1997
PMID: 9208853
Neurotransmitter release - four years of SNARE complexes.
Hanson PI, Heuser JE, Jahn R., Curr. Opin. Neurobiol. 7(3), 1997
PMID: 9232812
Export of cellubrevin from the endoplasmic reticulum is controlled by BAP31.
Annaert WG, Becker B, Kistner U, Reth M, Jahn R., J. Cell Biol. 139(6), 1997
PMID: 9396746
Two syntaxin homologues in the TGN/endosomal system of yeast.
Holthuis JC, Nichols BJ, Dhruvakumar S, Pelham HR., EMBO J. 17(1), 1998
PMID: 9427746
Syntaxin 12, a member of the syntaxin family localized to the endosome.
Tang BL, Tan AE, Lim LK, Lee SS, Low DY, Hong W., J. Biol. Chem. 273(12), 1998
PMID: 9507000
Seven novel mammalian SNARE proteins localize to distinct membrane compartments.
Advani RJ, Bae HR, Bock JB, Chao DS, Doung YC, Prekeris R, Yoo JS, Scheller RH., J. Biol. Chem. 273(17), 1998
PMID: 9553086
Protease resistance of syntaxin.SNAP-25.VAMP complexes. Implications for assembly and structure.
Poirier MA, Hao JC, Malkus PN, Chan C, Moore MF, King DS, Bennett MK., J. Biol. Chem. 273(18), 1998
PMID: 9556632
A novel tetanus neurotoxin-insensitive vesicle-associated membrane protein in SNARE complexes of the apical plasma membrane of epithelial cells.
Galli T, Zahraoui A, Vaidyanathan VV, Raposo G, Tian JM, Karin M, Niemann H, Louvard D., Mol. Biol. Cell 9(6), 1998
PMID: 9614185
Identification of a minimal core of the synaptic SNARE complex sufficient for reversible assembly and disassembly.
Fasshauer D, Eliason WK, Brunger AT, Jahn R., Biochemistry 37(29), 1998
PMID: 9671503
A model for structural similarity between different SNARE complexes based on sequence relationships.
Weimbs T, Mostov K, Low SH, Hofmann K., Trends Cell Biol. 8(7), 1998
PMID: 9714596
Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A.
Fernandez I, Ubach J, Dulubova I, Zhang X, Sudhof TC, Rizo J., Cell 94(6), 1998
PMID: 9753330
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution.
Sutton RB, Fasshauer D, Jahn R, Brunger AT., Nature 395(6700), 1998
PMID: 9759724
Reconstitution of retrograde transport from the Golgi to the ER in vitro.
Spang A, Schekman R., J. Cell Biol. 143(3), 1998
PMID: 9813082
Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth.
Martinez-Arca S, Alberts P, Zahraoui A, Louvard D, Galli T., J. Cell Biol. 149(4), 2000
PMID: 10811829
Membrane fusion and exocytosis.
Jahn R, Sudhof TC., Annu. Rev. Biochem. 68(), 1999
PMID: 10872468
Syntaxin 7 is localized to late endosome compartments, associates with Vamp 8, and Is required for late endosome-lysosome fusion.
Mullock BM, Smith CW, Ihrke G, Bright NA, Lindsay M, Parkinson EJ, Brooks DA, Parton RG, James DE, Luzio JP, Piper RC., Mol. Biol. Cell 11(9), 2000
PMID: 10982406
The R-SNARE endobrevin/VAMP-8 mediates homotypic fusion of early endosomes and late endosomes.
Antonin W, Holroyd C, Tikkanen R, Honing S, Jahn R., Mol. Biol. Cell 11(10), 2000
PMID: 11029036
Membrane traffic in endocytosis: insights from cell-free assays.
Gruenberg J, Howell KE., Annu. Rev. Cell Biol. 5(), 1989
PMID: 2557061
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