Functional Characterization of a Supramolecular Affinity Switch at the Single Molecule Level

Walhorn V, Schröder T, Mattay J, Anselmetti D (In Press)
Nanoscale 3(11): 4859-4865.

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Abstract / Bemerkung
Surface-immobilized and switchable resorcin[4]arene receptor molecules were quantitatively investigated with atomic force microscopy (AFM) and AFM-single molecule force spectroscopy (AFM-SMFS). The upper rim of the supramolecular receptor cavities was modified with two photodimerizable anthracene moieties. The molecular constitution can be externally switched and controlled by exposure to ultraviolet (UV) light and heat. The topography as well as the complexation affinity against small ammonium guest ions of the two isomers were investigated at the single molecule level. Our results demonstrate the feasibility to externally control the supramolecular receptor's affinity and simultaneously quantify and associate these binding properties with the structural change of the resorcin[4]arenes structure on the basis of the measured molecule corrugation height.
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Nanoscale
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3
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11
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4859-4865
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Walhorn V, Schröder T, Mattay J, Anselmetti D. Functional Characterization of a Supramolecular Affinity Switch at the Single Molecule Level. Nanoscale. In Press;3(11):4859-4865.
Walhorn, V., Schröder, T., Mattay, J., & Anselmetti, D. (In Press). Functional Characterization of a Supramolecular Affinity Switch at the Single Molecule Level. Nanoscale, 3(11), 4859-4865. doi:10.1039/C1NR10912J
Walhorn, V., Schröder, T., Mattay, J., and Anselmetti, D. (In Press). Functional Characterization of a Supramolecular Affinity Switch at the Single Molecule Level. Nanoscale 3, 4859-4865.
Walhorn, V., et al., In Press. Functional Characterization of a Supramolecular Affinity Switch at the Single Molecule Level. Nanoscale, 3(11), p 4859-4865.
V. Walhorn, et al., “Functional Characterization of a Supramolecular Affinity Switch at the Single Molecule Level”, Nanoscale, vol. 3, In Press, pp. 4859-4865.
Walhorn, V., Schröder, T., Mattay, J., Anselmetti, D.: Functional Characterization of a Supramolecular Affinity Switch at the Single Molecule Level. Nanoscale. 3, 4859-4865 (In Press).
Walhorn, Volker, Schröder, Tobias, Mattay, Jochen, and Anselmetti, Dario. “Functional Characterization of a Supramolecular Affinity Switch at the Single Molecule Level”. Nanoscale 3.11 (In Press): 4859-4865.

5 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

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