Aging-related changes of neural mechanisms underlying visual-spatial working memory
Piefke M, Onur ÖA, Fink GR (2012)
Neurobiology of Aging 33(7): 1284-1297.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Piefke, MartinaUniBi;
Onur, Özgür A.;
Fink, Gereon R.
Einrichtung
Abstract / Bemerkung
Capacities of the prefrontal cortex (PFC) such as working memory (WM) are known to decline with increasing age. However, it is unclear which neurofunctional mechanisms may underlie this aging-related cognitive decline. The finding that PFC activity tends to be less lateralized in older subjects has led to the assumption of a hemispheric asymmetry reduction in the PFC associated with aging (HAROLD). Using functional magnetic resonance imaging (fMRI), we here investigated aging-related neurofunctional alterations during the performance of a visual-spatial WM task with differential levels of difficulty. Older volunteers activated dorsolateral PFC regions bilaterally while young subjects recruited these areas only in the left hemisphere. These data corroborate the hemispheric asymmetry reduction in the PFC associated with aging (HAROLD) account. However, we also observed functional reorganizations in parieto-occipital areas, and with increasing WM demands, an aging-related reversed hemispheric asymmetry of prefrontal activations. Importantly, neither PFC nor parieto-occipital reorganizations prevented older participants from showing worse WM performance than young volunteers. We conclude that frontal-parietal functional reorganizations may reflect compensational mechanisms related to aging, but do not obviate diminished visual-spatial WM performance in older people.
Stichworte
Prefrontal cortex;
Visual-spatial attention;
Executive functions;
Parietal cortex;
Biological aging;
fMRI
Erscheinungsjahr
2012
Zeitschriftentitel
Neurobiology of Aging
Band
33
Ausgabe
7
Seite(n)
1284-1297
ISSN
0197-4580
Page URI
https://pub.uni-bielefeld.de/record/2279579
Zitieren
Piefke M, Onur ÖA, Fink GR. Aging-related changes of neural mechanisms underlying visual-spatial working memory. Neurobiology of Aging. 2012;33(7):1284-1297.
Piefke, M., Onur, Ö. A., & Fink, G. R. (2012). Aging-related changes of neural mechanisms underlying visual-spatial working memory. Neurobiology of Aging, 33(7), 1284-1297. https://doi.org/10.1016/j.neurobiolaging.2010.10.014
Piefke, Martina, Onur, Özgür A., and Fink, Gereon R. 2012. “Aging-related changes of neural mechanisms underlying visual-spatial working memory”. Neurobiology of Aging 33 (7): 1284-1297.
Piefke, M., Onur, Ö. A., and Fink, G. R. (2012). Aging-related changes of neural mechanisms underlying visual-spatial working memory. Neurobiology of Aging 33, 1284-1297.
Piefke, M., Onur, Ö.A., & Fink, G.R., 2012. Aging-related changes of neural mechanisms underlying visual-spatial working memory. Neurobiology of Aging, 33(7), p 1284-1297.
M. Piefke, Ö.A. Onur, and G.R. Fink, “Aging-related changes of neural mechanisms underlying visual-spatial working memory”, Neurobiology of Aging, vol. 33, 2012, pp. 1284-1297.
Piefke, M., Onur, Ö.A., Fink, G.R.: Aging-related changes of neural mechanisms underlying visual-spatial working memory. Neurobiology of Aging. 33, 1284-1297 (2012).
Piefke, Martina, Onur, Özgür A., and Fink, Gereon R. “Aging-related changes of neural mechanisms underlying visual-spatial working memory”. Neurobiology of Aging 33.7 (2012): 1284-1297.
Daten bereitgestellt von European Bioinformatics Institute (EBI)
14 Zitationen in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
Working memory performance in the elderly relates to theta-alpha oscillations and is predicted by parahippocampal and striatal integrity.
Steiger TK, Herweg NA, Menz MM, Bunzeck N., Sci Rep 9(1), 2019
PMID: 30679512
Steiger TK, Herweg NA, Menz MM, Bunzeck N., Sci Rep 9(1), 2019
PMID: 30679512
Influences of age, mental workload, and flight experience on cognitive performance and prefrontal activity in private pilots: a fNIRS study.
Causse M, Chua ZK, Rémy F., Sci Rep 9(1), 2019
PMID: 31118436
Causse M, Chua ZK, Rémy F., Sci Rep 9(1), 2019
PMID: 31118436
Functional Hemispheric (A)symmetries in the Aged Brain-Relevance for Working Memory.
Esteves M, Magalhães R, Marques P, Castanho TC, Portugal-Nunes C, Soares JM, Almeida A, Santos NC, Sousa N, Leite-Almeida H., Front Aging Neurosci 10(), 2018
PMID: 29593523
Esteves M, Magalhães R, Marques P, Castanho TC, Portugal-Nunes C, Soares JM, Almeida A, Santos NC, Sousa N, Leite-Almeida H., Front Aging Neurosci 10(), 2018
PMID: 29593523
Beta Oscillatory Dynamics in the Prefrontal and Superior Temporal Cortices Predict Spatial Working Memory Performance.
Proskovec AL, Wiesman AI, Heinrichs-Graham E, Wilson TW., Sci Rep 8(1), 2018
PMID: 29855522
Proskovec AL, Wiesman AI, Heinrichs-Graham E, Wilson TW., Sci Rep 8(1), 2018
PMID: 29855522
Neural Correlates of Working Memory Maintenance in Advanced Aging: Evidence From fMRI.
Suzuki M, Kawagoe T, Nishiguchi S, Abe N, Otsuka Y, Nakai R, Asano K, Yamada M, Yoshikawa S, Sekiyama K., Front Aging Neurosci 10(), 2018
PMID: 30459595
Suzuki M, Kawagoe T, Nishiguchi S, Abe N, Otsuka Y, Nakai R, Asano K, Yamada M, Yoshikawa S, Sekiyama K., Front Aging Neurosci 10(), 2018
PMID: 30459595
Age differences in the motor control of speech: An fMRI study of healthy aging.
Tremblay P, Sato M, Deschamps I., Hum Brain Mapp 38(5), 2017
PMID: 28263012
Tremblay P, Sato M, Deschamps I., Hum Brain Mapp 38(5), 2017
PMID: 28263012
Running wheel training does not change neurogenesis levels or alter working memory tasks in adult rats.
Acevedo-Triana CA, Rojas MJ, Cardenas P F., PeerJ 5(), 2017
PMID: 28503368
Acevedo-Triana CA, Rojas MJ, Cardenas P F., PeerJ 5(), 2017
PMID: 28503368
Language processing of auditory cortex revealed by functional magnetic resonance imaging in presbycusis patients.
Chen X, Wang M, Deng Y, Liang Y, Li J, Chen S., Acta Otolaryngol 136(2), 2016
PMID: 26503708
Chen X, Wang M, Deng Y, Liang Y, Li J, Chen S., Acta Otolaryngol 136(2), 2016
PMID: 26503708
Aging and the Effects of Exploratory Behavior on Spatial Memory.
Varner KM, Dopkins S, Philbeck JW., Int J Aging Hum Dev 82(2-3), 2016
PMID: 26758675
Varner KM, Dopkins S, Philbeck JW., Int J Aging Hum Dev 82(2-3), 2016
PMID: 26758675
The neural correlates of spatial and object working memory in elderly and Parkinson's disease subjects.
Caminiti SP, Siri C, Guidi L, Antonini A, Perani D., Behav Neurol 2015(), 2015
PMID: 25861157
Caminiti SP, Siri C, Guidi L, Antonini A, Perani D., Behav Neurol 2015(), 2015
PMID: 25861157
Putting age-related task activation into large-scale brain networks: A meta-analysis of 114 fMRI studies on healthy aging.
Li HJ, Hou XH, Liu HH, Yue CL, Lu GM, Zuo XN., Neurosci Biobehav Rev 57(), 2015
PMID: 26318367
Li HJ, Hou XH, Liu HH, Yue CL, Lu GM, Zuo XN., Neurosci Biobehav Rev 57(), 2015
PMID: 26318367
A systematic review of type 2 diabetes mellitus and hypertension in imaging studies of cognitive aging: time to establish new norms.
Meusel LA, Kansal N, Tchistiakova E, Yuen W, MacIntosh BJ, Greenwood CE, Anderson ND., Front Aging Neurosci 6(), 2014
PMID: 25071557
Meusel LA, Kansal N, Tchistiakova E, Yuen W, MacIntosh BJ, Greenwood CE, Anderson ND., Front Aging Neurosci 6(), 2014
PMID: 25071557
An exploratory study of the effects of spatial working-memory load on prefrontal activation in low- and high-performing elderly.
Vermeij A, van Beek AH, Reijs BL, Claassen JA, Kessels RP., Front Aging Neurosci 6(), 2014
PMID: 25414665
Vermeij A, van Beek AH, Reijs BL, Claassen JA, Kessels RP., Front Aging Neurosci 6(), 2014
PMID: 25414665
Learning real-life cognitive abilities in a novel 360°-virtual reality supermarket: a neuropsychological study of healthy participants and patients with epilepsy.
Grewe P, Kohsik A, Flentge D, Dyck E, Botsch M, Winter Y, Markowitsch HJ, Bien CG, Piefke M., J Neuroeng Rehabil 10(), 2013
PMID: 23618596
Grewe P, Kohsik A, Flentge D, Dyck E, Botsch M, Winter Y, Markowitsch HJ, Bien CG, Piefke M., J Neuroeng Rehabil 10(), 2013
PMID: 23618596
78 References
Daten bereitgestellt von Europe PubMed Central.
Aging and visual processing: declines in spatial not temporal integration
Andersen, Vis. Res 48(), 2008
Andersen, Vis. Res 48(), 2008
Left inferior parietal cortex integrates time and space during collision judgments.
Assmus A, Marshall JC, Ritzl A, Noth J, Zilles K, Fink GR., Neuroimage 20 Suppl 1(), 2003
PMID: 14597300
Assmus A, Marshall JC, Ritzl A, Noth J, Zilles K, Fink GR., Neuroimage 20 Suppl 1(), 2003
PMID: 14597300
An inventory for measuring depression.
BECK AT, WARD CH, MENDELSON M, MOCK J, ERBAUGH J., Arch. Gen. Psychiatry 4(), 1961
PMID: 13688369
BECK AT, WARD CH, MENDELSON M, MOCK J, ERBAUGH J., Arch. Gen. Psychiatry 4(), 1961
PMID: 13688369
Benton, 1976
Spatial reference and working memory across the lifespan of male Fischer 344 rats.
Bizon JL, LaSarge CL, Montgomery KS, McDermott AN, Setlow B, Griffith WH., Neurobiol. Aging 30(4), 2007
PMID: 17889407
Bizon JL, LaSarge CL, Montgomery KS, McDermott AN, Setlow B, Griffith WH., Neurobiol. Aging 30(4), 2007
PMID: 17889407
What “works” in working memory?
Bledowski, J. Neurosci 29(), 2009
Bledowski, J. Neurosci 29(), 2009
A theory of cognitive control, aging cognition, and neuromodulation.
Braver TS, Barch DM., Neurosci Biobehav Rev 26(7), 2002
PMID: 12470692
Braver TS, Barch DM., Neurosci Biobehav Rev 26(7), 2002
PMID: 12470692
Protein kinase C activity is associated with prefrontal cortical decline in aging.
Brennan AR, Yuan P, Dickstein DL, Rocher AB, Hof PR, Manji H, Arnsten AF., Neurobiol. Aging 30(5), 2007
PMID: 17919783
Brennan AR, Yuan P, Dickstein DL, Rocher AB, Hof PR, Manji H, Arnsten AF., Neurobiol. Aging 30(5), 2007
PMID: 17919783
The visuospatial sketchpad for mental images: testing the multicomponent model of working memory.
Bruyer R, Scailquin JC., Acta Psychol (Amst) 98(1), 1998
PMID: 9581123
Bruyer R, Scailquin JC., Acta Psychol (Amst) 98(1), 1998
PMID: 9581123
Cognitive neuroscience of aging: contributions of functional neuroimaging.
Cabeza R., Scand J Psychol 42(3), 2001
PMID: 11501741
Cabeza R., Scand J Psychol 42(3), 2001
PMID: 11501741
Aging gracefully: compensatory brain activity in high-performing older adults.
Cabeza R, Anderson ND, Locantore JK, McIntosh AR., Neuroimage 17(3), 2002
PMID: 12414279
Cabeza R, Anderson ND, Locantore JK, McIntosh AR., Neuroimage 17(3), 2002
PMID: 12414279
The relationship between white matter brain metabolites and cognition in normal aging: the GENIE study.
Charlton RA, McIntyre DJ, Howe FA, Morris RG, Markus HS., Brain Res. 1164(), 2007
PMID: 17632090
Charlton RA, McIntyre DJ, Howe FA, Morris RG, Markus HS., Brain Res. 1164(), 2007
PMID: 17632090
Zooming in and zooming out of the attentional focus: an FMRI study.
Chen Q, Marshall JC, Weidner R, Fink GR., Cereb. Cortex 19(4), 2008
PMID: 18689860
Chen Q, Marshall JC, Weidner R, Fink GR., Cereb. Cortex 19(4), 2008
PMID: 18689860
Aging and integrating spatial mental models.
Copeland DE, Radvansky GA., Psychol Aging 22(3), 2007
PMID: 17874955
Copeland DE, Radvansky GA., Psychol Aging 22(3), 2007
PMID: 17874955
Control of goal-directed and stimulus-driven attention in the brain.
Corbetta M, Shulman GL., Nat. Rev. Neurosci. 3(3), 2002
PMID: 11994752
Corbetta M, Shulman GL., Nat. Rev. Neurosci. 3(3), 2002
PMID: 11994752
Assessment of memory complaint in age-associated memory impairment: the MAC-Q.
Crook TH 3rd, Feher EP, Larrabee GJ., Int Psychogeriatr 4(2), 1992
PMID: 1477304
Crook TH 3rd, Feher EP, Larrabee GJ., Int Psychogeriatr 4(2), 1992
PMID: 1477304
Molecular imaging of the dopaminergic system and its association with human cognitive function.
Cropley VL, Fujita M, Innis RB, Nathan PJ., Biol. Psychiatry 59(10), 2006
PMID: 16682268
Cropley VL, Fujita M, Innis RB, Nathan PJ., Biol. Psychiatry 59(10), 2006
PMID: 16682268
On why not to rush older adults--relying on reactive cognitive control can effectively reduce errors at the expense of slowed responses.
Czernochowski D, Nessler D, Friedman D., Psychophysiology 47(4), 2010
PMID: 20136730
Czernochowski D, Nessler D, Friedman D., Psychophysiology 47(4), 2010
PMID: 20136730
From cognitive to neural models of working memory.
D'Esposito M., Philos. Trans. R. Soc. Lond., B, Biol. Sci. 362(1481), 2007
PMID: 17400538
D'Esposito M., Philos. Trans. R. Soc. Lond., B, Biol. Sci. 362(1481), 2007
PMID: 17400538
Maintenance versus manipulation of information held in working memory: an event-related fMRI study.
D'Esposito M, Postle BR, Ballard D, Lease J., Brain Cogn 41(1), 1999
PMID: 10536086
D'Esposito M, Postle BR, Ballard D, Lease J., Brain Cogn 41(1), 1999
PMID: 10536086
Executive control during episodic retrieval: multiple prefrontal processes subserve source memory.
Dobbins IG, Foley H, Schacter DL, Wagner AD., Neuron 35(5), 2002
PMID: 12372291
Dobbins IG, Foley H, Schacter DL, Wagner AD., Neuron 35(5), 2002
PMID: 12372291
Hemispheric asymmetry and aging: right hemisphere decline or asymmetry reduction.
Dolcos F, Rice HJ, Cabeza R., Neurosci Biobehav Rev 26(7), 2002
PMID: 12470693
Dolcos F, Rice HJ, Cabeza R., Neurosci Biobehav Rev 26(7), 2002
PMID: 12470693
Age-related changes in neural activity during performance matched working memory manipulation.
Emery L, Heaven TJ, Paxton JL, Braver TS., Neuroimage 42(4), 2008
PMID: 18634891
Emery L, Heaven TJ, Paxton JL, Braver TS., Neuroimage 42(4), 2008
PMID: 18634891
The mind's eye--precuneus activation in memory-related imagery.
Fletcher PC, Frith CD, Baker SC, Shallice T, Frackowiak RS, Dolan RJ., Neuroimage 2(3), 1995
PMID: 9343602
Fletcher PC, Frith CD, Baker SC, Shallice T, Frackowiak RS, Dolan RJ., Neuroimage 2(3), 1995
PMID: 9343602
Tracking the mind's image in the brain I: time-resolved fMRI during visuospatial mental imagery.
Formisano E, Linden DE, Di Salle F, Trojano L, Esposito F, Sack AT, Grossi D, Zanella FE, Goebel R., Neuron 35(1), 2002
PMID: 12123618
Formisano E, Linden DE, Di Salle F, Trojano L, Esposito F, Sack AT, Grossi D, Zanella FE, Goebel R., Neuron 35(1), 2002
PMID: 12123618
Spatial registration and normalization of images
Friston, Hum. Brain Mapp 3(), 1995
Friston, Hum. Brain Mapp 3(), 1995
Statistical parametric maps in functional imaging: a general linear approach
Friston, Hum. Brain Mapp 2(), 1995
Friston, Hum. Brain Mapp 2(), 1995
Functional interactions between prefrontal and visual association cortex contribute to top-down modulation of visual processing
Gazzaley, Cereb. Cortex 17 suppl 1(), 2007
Gazzaley, Cereb. Cortex 17 suppl 1(), 2007
Maintenance and manipulation in spatial working memory: dissociations in the prefrontal cortex.
Glahn DC, Kim J, Cohen MS, Poutanen VP, Therman S, Bava S, Van Erp TG, Manninen M, Huttunen M, Lonnqvist J, Standertskjold-Nordenstam CG, Cannon TD., Neuroimage 17(1), 2002
PMID: 12482077
Glahn DC, Kim J, Cohen MS, Poutanen VP, Therman S, Bava S, Van Erp TG, Manninen M, Huttunen M, Lonnqvist J, Standertskjold-Nordenstam CG, Cannon TD., Neuroimage 17(1), 2002
PMID: 12482077
Visual function and cognitive aging: differential role of contrast sensitivity in verbal versus spatial tasks.
Glass JM., Psychol Aging 22(2), 2007
PMID: 17563179
Glass JM., Psychol Aging 22(2), 2007
PMID: 17563179
Crossmodal processing of object features in human anterior intraparietal cortex: an fMRI study implies equivalencies between humans and monkeys.
Grefkes C, Weiss PH, Zilles K, Fink GR., Neuron 35(1), 2002
PMID: 12123617
Grefkes C, Weiss PH, Zilles K, Fink GR., Neuron 35(1), 2002
PMID: 12123617
Härting, 2000
Evaluating frontal and parietal contributions to spatial working memory with repetitive transcranial magnetic stimulation.
Hamidi M, Tononi G, Postle BR., Brain Res. 1230(), 2008
PMID: 18662678
Hamidi M, Tononi G, Postle BR., Brain Res. 1230(), 2008
PMID: 18662678
Explaining age differences in temporal working memory.
Hartman M, Warren LH., Psychol Aging 20(4), 2005
PMID: 16420139
Hartman M, Warren LH., Psychol Aging 20(4), 2005
PMID: 16420139
Neural activation during response competition.
Hazeltine E, Poldrack R, Gabrieli JD., J Cogn Neurosci 12 Suppl 2(), 2000
PMID: 11506652
Hazeltine E, Poldrack R, Gabrieli JD., J Cogn Neurosci 12 Suppl 2(), 2000
PMID: 11506652
Age differences in mental scanning of locomotor maps.
Iachini T, Poderico C, Ruggiero G, Iavarone A., Disabil Rehabil 27(13), 2005
PMID: 16096226
Iachini T, Poderico C, Ruggiero G, Iavarone A., Disabil Rehabil 27(13), 2005
PMID: 16096226
Age-related shifts in brain activity dynamics during task switching.
Jimura K, Braver TS., Cereb. Cortex 20(6), 2009
PMID: 19805420
Jimura K, Braver TS., Cereb. Cortex 20(6), 2009
PMID: 19805420
Maintenance of real objects and their verbal designations in working memory.
Kaiser S, Kopka ML, Rentrop M, Walther S, Kronmuller K, Olbrich R, Weisbrod M, Stippich C., Neurosci. Lett. 469(1), 2009
PMID: 19932154
Kaiser S, Kopka ML, Rentrop M, Walther S, Kronmuller K, Olbrich R, Weisbrod M, Stippich C., Neurosci. Lett. 469(1), 2009
PMID: 19932154
Kaplan, 1983
Comparison of adult age differences in verbal and visuo-spatial memory: the importance of 'pure', parallel and validated measures.
Kemps E, Newson R., J Clin Exp Neuropsychol 28(3), 2006
PMID: 16618624
Kemps E, Newson R., J Clin Exp Neuropsychol 28(3), 2006
PMID: 16618624
Kessler, 1990
Development of a superior frontal-intraparietal network for visuo-spatial working memory.
Klingberg T., Neuropsychologia 44(11), 2006
PMID: 16405923
Klingberg T., Neuropsychologia 44(11), 2006
PMID: 16405923
Event-related potentials in young and elderly adults during a visual spatial working memory task.
Knott V, Millar A, Dulude L, Bradford L, Alwahhabi F, Lau T, Shea C, Wiens A., Clin EEG Neurosci 35(4), 2004
PMID: 15493533
Knott V, Millar A, Dulude L, Bradford L, Alwahhabi F, Lau T, Shea C, Wiens A., Clin EEG Neurosci 35(4), 2004
PMID: 15493533
The hemodynamics of cognitive control: the level of concentration of oxygenated hemoglobin in the superior prefrontal cortex varies as a function of performance in a modified Stroop task.
Leon-Carrion J, Damas-Lopez J, Martin-Rodriguez JF, Dominguez-Roldan JM, Murillo-Cabezas F, Barroso Y Martin JM, Dominguez-Morales MR., Behav. Brain Res. 193(2), 2008
PMID: 18606191
Leon-Carrion J, Damas-Lopez J, Martin-Rodriguez JF, Dominguez-Roldan JM, Murillo-Cabezas F, Barroso Y Martin JM, Dominguez-Morales MR., Behav. Brain Res. 193(2), 2008
PMID: 18606191
Under-recruitment and nonselective recruitment: dissociable neural mechanisms associated with aging.
Logan JM, Sanders AL, Snyder AZ, Morris JC, Buckner RL., Neuron 33(5), 2002
PMID: 11879658
Logan JM, Sanders AL, Snyder AZ, Morris JC, Buckner RL., Neuron 33(5), 2002
PMID: 11879658
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease.
Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, van Belle G, Berg L., Neurology 41(4), 1991
PMID: 2011243
Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, van Belle G, Berg L., Neurology 41(4), 1991
PMID: 2011243
Age-related changes in fronto-parietal networks during spatial memory: an ERP study.
Muller NG, Knight RT., Brain Res Cogn Brain Res 13(2), 2002
PMID: 11958965
Muller NG, Knight RT., Brain Res Cogn Brain Res 13(2), 2002
PMID: 11958965
White matter changes compromise prefrontal cortex function in healthy elderly individuals.
Nordahl CW, Ranganath C, Yonelinas AP, Decarli C, Fletcher E, Jagust WJ., J Cogn Neurosci 18(3), 2006
PMID: 16513006
Nordahl CW, Ranganath C, Yonelinas AP, Decarli C, Fletcher E, Jagust WJ., J Cogn Neurosci 18(3), 2006
PMID: 16513006
The assessment and analysis of handedness: the Edinburgh inventory.
Oldfield RC., Neuropsychologia 9(1), 1971
PMID: 5146491
Oldfield RC., Neuropsychologia 9(1), 1971
PMID: 5146491
Cognitive control, goal maintenance, and prefrontal function in healthy aging.
Paxton JL, Barch DM, Racine CA, Braver TS., Cereb. Cortex 18(5), 2007
PMID: 17804479
Paxton JL, Barch DM, Racine CA, Braver TS., Cereb. Cortex 18(5), 2007
PMID: 17804479
Lateral prefrontal cortex: architectonic and functional organization.
Petrides M., Philos. Trans. R. Soc. Lond., B, Biol. Sci. 360(1456), 2005
PMID: 15937012
Petrides M., Philos. Trans. R. Soc. Lond., B, Biol. Sci. 360(1456), 2005
PMID: 15937012
Motor areas of the medial wall: a review of their location and functional activation.
Picard N, Strick PL., Cereb. Cortex 6(3), 1996
PMID: 8670662
Picard N, Strick PL., Cereb. Cortex 6(3), 1996
PMID: 8670662
Differential remoteness and emotional tone modulate the neural correlates of autobiographical memory.
Piefke M, Weiss PH, Zilles K, Markowitsch HJ, Fink GR., Brain 126(Pt 3), 2003
PMID: 12566286
Piefke M, Weiss PH, Zilles K, Markowitsch HJ, Fink GR., Brain 126(Pt 3), 2003
PMID: 12566286
Neurofunctional modulation of brain regions by distinct forms of motor cognition and movement features.
Piefke M, Kramer K, Korte M, Schulte-Ruther M, Korte JM, Wohlschlager AM, Weber J, Shah NJ, Huber W, Fink GR., Hum Brain Mapp 30(2), 2009
PMID: 18064585
Piefke M, Kramer K, Korte M, Schulte-Ruther M, Korte JM, Wohlschlager AM, Weber J, Shah NJ, Huber W, Fink GR., Hum Brain Mapp 30(2), 2009
PMID: 18064585
Delay-period activity in the prefrontal cortex: one function is sensory gating.
Postle BR., J Cogn Neurosci 17(11), 2005
PMID: 16269105
Postle BR., J Cogn Neurosci 17(11), 2005
PMID: 16269105
Activity in human frontal cortex associated with spatial working memory and saccadic behavior.
Postle BR, Berger JS, Taich AM, D'Esposito M., J Cogn Neurosci 12 Suppl 2(), 2000
PMID: 11506643
Postle BR, Berger JS, Taich AM, D'Esposito M., J Cogn Neurosci 12 Suppl 2(), 2000
PMID: 11506643
The where and how of attention-based rehearsal in spatial working memory.
Postle BR, Awh E, Jonides J, Smith EE, D'Esposito M., Brain Res Cogn Brain Res 20(2), 2004
PMID: 15183391
Postle BR, Awh E, Jonides J, Smith EE, D'Esposito M., Brain Res Cogn Brain Res 20(2), 2004
PMID: 15183391
White matter lesions account for all age-related declines in speed but not in intelligence.
Rabbitt P, Scott M, Lunn M, Thacker N, Lowe C, Pendleton N, Horan M, Jackson A., Neuropsychology 21(3), 2007
PMID: 17484599
Rabbitt P, Scott M, Lunn M, Thacker N, Lowe C, Pendleton N, Horan M, Jackson A., Neuropsychology 21(3), 2007
PMID: 17484599
Region-specific changes in prefrontal function with age: a review of PET and fMRI studies on working and episodic memory.
Rajah MN, D'Esposito M., Brain 128(Pt 9), 2005
PMID: 16049041
Rajah MN, D'Esposito M., Brain 128(Pt 9), 2005
PMID: 16049041
Age-related deficits in generation and manipulation of mental images: II. The role of dorsolateral prefrontal cortex.
Raz N, Briggs SD, Marks W, Acker JD., Psychol Aging 14(3), 1999
PMID: 10509698
Raz N, Briggs SD, Marks W, Acker JD., Psychol Aging 14(3), 1999
PMID: 10509698
Validity of the trail making test as an indicator of organic brain damage
Reitan, Percept. Mot. Skills 73(), 1958
Reitan, Percept. Mot. Skills 73(), 1958
The effect of non-visual working memory load on top-down modulation of visual processing.
Rissman J, Gazzaley A, D'Esposito M., Neuropsychologia 47(7), 2009
PMID: 19397858
Rissman J, Gazzaley A, D'Esposito M., Neuropsychologia 47(7), 2009
PMID: 19397858
Isolating the neural mechanisms of age-related changes in human working memory.
Rypma B, D'Esposito M., Nat. Neurosci. 3(5), 2000
PMID: 10769393
Rypma B, D'Esposito M., Nat. Neurosci. 3(5), 2000
PMID: 10769393
Tracking the mind's image in the brain II: transcranial magnetic stimulation reveals parietal asymmetry in visuospatial imagery.
Sack AT, Sperling JM, Prvulovic D, Formisano E, Goebel R, Di Salle F, Dierks T, Linden DE., Neuron 35(1), 2002
PMID: 12123619
Sack AT, Sperling JM, Prvulovic D, Formisano E, Goebel R, Di Salle F, Dierks T, Linden DE., Neuron 35(1), 2002
PMID: 12123619
[Practical application of the CERAD test battery as a neuropsychological dementia screening test]
Satzger W, Hampel H, Padberg F, Burger K, Nolde T, Ingrassia G, Engel RR., Nervenarzt 72(3), 2001
PMID: 11268764
Satzger W, Hampel H, Padberg F, Burger K, Nolde T, Ingrassia G, Engel RR., Nervenarzt 72(3), 2001
PMID: 11268764
Disentangling the prefrontal network for rule selection by means of a non-verbal variant of the Wisconsin Card Sorting Test
Specht, Hum. Brain Mapp 30(), 2008
Specht, Hum. Brain Mapp 30(), 2008
LPS-K—Eine LPS-Kurzform für hirngeschädigte Patienten; mit Anleitung zur psychometrischen Einzelfalldiagnostik
Sturm, Diagnostica 29(), 1983
Sturm, Diagnostica 29(), 1983
Sturm, 1993
Neural correlates of visuospatial imagery.
Suchan B, Yaguez L, Wunderlich G, Canavan AG, Herzog H, Tellmann L, Homberg V, Seitz RJ., Behav. Brain Res. 131(1-2), 2002
PMID: 11844583
Suchan B, Yaguez L, Wunderlich G, Canavan AG, Herzog H, Tellmann L, Homberg V, Seitz RJ., Behav. Brain Res. 131(1-2), 2002
PMID: 11844583
Tewes, 1991
Aging and visual short-term memory: effects of object type and information load.
Vaughan L, Hartman M., Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 17(1), 2009
PMID: 19626476
Vaughan L, Hartman M., Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 17(1), 2009
PMID: 19626476
Aging, task complexity, and efficiency modes: the influence of working memory involvement on age differences in response times for verbal and visuospatial tasks.
Verhaeghen P, Cerella J, Basak C., Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 13(2), 2006
PMID: 16807201
Verhaeghen P, Cerella J, Basak C., Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 13(2), 2006
PMID: 16807201
Dedifferentiation in the visual cortex: an fMRI investigation of individual differences in older adults.
Voss MW, Erickson KI, Chaddock L, Prakash RS, Colcombe SJ, Morris KS, Doerksen S, Hu L, McAuley E, Kramer AF., Brain Res. 1244(), 2008
PMID: 18848823
Voss MW, Erickson KI, Chaddock L, Prakash RS, Colcombe SJ, Morris KS, Doerksen S, Hu L, McAuley E, Kramer AF., Brain Res. 1244(), 2008
PMID: 18848823
Prefrontal contributions to executive control: fMRI evidence for functional distinctions within lateral Prefrontal cortex.
Wagner AD, Maril A, Bjork RA, Schacter DL., Neuroimage 14(6), 2001
PMID: 11707089
Wagner AD, Maril A, Bjork RA, Schacter DL., Neuroimage 14(6), 2001
PMID: 11707089
Color-word matching stroop task: separating interference and response conflict.
Zysset S, Muller K, Lohmann G, von Cramon DY., Neuroimage 13(1), 2001
PMID: 11133306
Zysset S, Muller K, Lohmann G, von Cramon DY., Neuroimage 13(1), 2001
PMID: 11133306
Export
Markieren/ Markierung löschen
Markierte Publikationen
Web of Science
Dieser Datensatz im Web of Science®Quellen
PMID: 21130531
PubMed | Europe PMC
Suchen in
Google Scholar