Environmental risk assessment of ivermectin – A case study

Liebig M, Fernandez A, Blübaum-Gronau E, Boxall A, Brinke M, Carbonell G, Egeler P, Fernandez C, Fink G, Garric J, Halling B, et al. (2010)
Integrated Environmental Assessment and Mangagement 6(S1): 567-587.

Zeitschriftenaufsatz | Englisch
 
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Liebig, M; Fernandez, A; Blübaum-Gronau, E; Boxall, A.; Brinke, M.; Carbonell, G.; Egeler, P.; Fernandez, C.; Fink, G.; Garric, J.; Halling, B.; Knacker, T.
Alle
Erscheinungsjahr
2010
Zeitschriftentitel
Integrated Environmental Assessment and Mangagement
Band
6
Ausgabe
S1
Seite(n)
567-587
ISSN
1551-3777
Page URI
https://pub.uni-bielefeld.de/record/1928119

Zitieren

Liebig M, Fernandez A, Blübaum-Gronau E, et al. Environmental risk assessment of ivermectin – A case study. Integrated Environmental Assessment and Mangagement. 2010;6(S1):567-587.
Liebig, M., Fernandez, A., Blübaum-Gronau, E., Boxall, A., Brinke, M., Carbonell, G., Egeler, P., et al. (2010). Environmental risk assessment of ivermectin – A case study. Integrated Environmental Assessment and Mangagement, 6(S1), 567-587. https://doi.org/10.1002/ieam.96
Liebig, M, Fernandez, A, Blübaum-Gronau, E, Boxall, A., Brinke, M., Carbonell, G., Egeler, P., et al. 2010. “Environmental risk assessment of ivermectin – A case study”. Integrated Environmental Assessment and Mangagement 6 (S1): 567-587.
Liebig, M., Fernandez, A., Blübaum-Gronau, E., Boxall, A., Brinke, M., Carbonell, G., Egeler, P., Fernandez, C., Fink, G., Garric, J., et al. (2010). Environmental risk assessment of ivermectin – A case study. Integrated Environmental Assessment and Mangagement 6, 567-587.
Liebig, M., et al., 2010. Environmental risk assessment of ivermectin – A case study. Integrated Environmental Assessment and Mangagement, 6(S1), p 567-587.
M. Liebig, et al., “Environmental risk assessment of ivermectin – A case study”, Integrated Environmental Assessment and Mangagement, vol. 6, 2010, pp. 567-587.
Liebig, M., Fernandez, A., Blübaum-Gronau, E., Boxall, A., Brinke, M., Carbonell, G., Egeler, P., Fernandez, C., Fink, G., Garric, J., Halling, B., Knacker, T., Krogh, K., Küster, A., Löffler, D., Angel, M., Cots, P., Pope, L., Prasse, C., Römbke, J., Rönnefahrt, I., Schneider, M., Schweitzer, N., Tarazona, J., Ternes, T., Traunspurger, W., Wehrhan, K., Duis, K.: Environmental risk assessment of ivermectin – A case study. Integrated Environmental Assessment and Mangagement. 6, 567-587 (2010).
Liebig, M, Fernandez, A, Blübaum-Gronau, E, Boxall, A., Brinke, M., Carbonell, G., Egeler, P., Fernandez, C., Fink, G., Garric, J., Halling, B., Knacker, T., Krogh, K., Küster, A., Löffler, D., Angel, M., Cots, P., Pope, L., Prasse, C., Römbke, J., Rönnefahrt, I., Schneider, M., Schweitzer, N., Tarazona, J., Ternes, T., Traunspurger, Walter, Wehrhan, K., and Duis, K. “Environmental risk assessment of ivermectin – A case study”. Integrated Environmental Assessment and Mangagement 6.S1 (2010): 567-587.

27 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

First assessment of the comparative toxicity of ivermectin and moxidectin in adult dung beetles: Sub-lethal symptoms and pre-lethal consequences.
Verdú JR, Cortez V, Martinez-Pinna J, Ortiz AJ, Lumaret JP, Lobo JM, Sánchez-Piñero F, Numa C., Sci Rep 8(1), 2018
PMID: 30291291
Automated thin-film microextraction coupled to a flow-through cell: somewhere in between passive and active sampling.
Wohde M, Bartz JO, Böhm L, Hartwig C, Keil BM, Martin K, Düring RA., Anal Bioanal Chem 409(8), 2017
PMID: 28012111
Toxicity of four veterinary pharmaceuticals on the survival and reproduction of Folsomia candida in tropical soils.
Zortéa T, Segat JC, Maccari AP, Sousa JP, Da Silva AS, Baretta D., Chemosphere 173(), 2017
PMID: 28131090
Model-predicted occurrence of multiple pharmaceuticals in Swedish surface waters and their flushing to the Baltic Sea.
Lindim C, van Gils J, Cousins IT, Kühne R, Georgieva D, Kutsarova S, Mekenyan O., Environ Pollut 223(), 2017
PMID: 28153413
Aquatic toxicity of ivermectin in cattle dung assessed using microcosms.
Mesa LM, Lindt I, Negro L, Gutierrez MF, Mayora G, Montalto L, Ballent M, Lifschitz A., Ecotoxicol Environ Saf 144(), 2017
PMID: 28654874
Three methods for integration of environmental risk into the benefit-risk assessment of veterinary medicinal products.
Chapman JL, Porsch L, Vidaurre R, Backhaus T, Sinclair C, Jones G, Boxall ABA., Sci Total Environ 605-606(), 2017
PMID: 28675879
Acute Toxicity and Environmental Risks of Five Veterinary Pharmaceuticals for Aquatic Macroinvertebrates.
Bundschuh M, Hahn T, Ehrlich B, Höltge S, Kreuzig R, Schulz R., Bull Environ Contam Toxicol 96(2), 2016
PMID: 26408031
Mobility of pharmaceutical compounds in the terrestrial environment: Adsorption kinetics of the macrocyclic lactone eprinomectin in soils.
Vassilis LD, George BC, Charalampos PG, Athina PV, Xanthippos KN., Chemosphere 144(), 2016
PMID: 26469933
Effects of ivermectin on Danio rerio: a multiple endpoint approach: behaviour, weight and subcellular markers.
Domingues I, Oliveira R, Soares AM, Amorim MJ., Ecotoxicology 25(3), 2016
PMID: 26769347
Pharmaceuticals in the environment--Global occurrences and perspectives.
aus der Beek T, Weber FA, Bergmann A, Hickmann S, Ebert I, Hein A, Küster A., Environ Toxicol Chem 35(4), 2016
PMID: 26666847
Nontarget effects of ivermectin residues on earthworms and springtails dwelling beneath dung of treated cattle in four countries.
Scheffczyk A, Floate KD, Blanckenhorn WU, Düring RA, Klockner A, Lahr J, Lumaret JP, Salamon JA, Tixier T, Wohde M, Römbke J., Environ Toxicol Chem 35(8), 2016
PMID: 26565894
Effects of ivermectin application on the diversity and function of dung and soil fauna: Regulatory and scientific background information.
Adler N, Bachmann J, Blanckenhorn WU, Floate KD, Jensen J, Römbke J., Environ Toxicol Chem 35(8), 2016
PMID: 26573955
Effect of ivermectin on the larvae of Anopheles gambiae and Culex quinquefasciatus.
Derua YA, Malongo BB, Simonsen PE., Parasit Vectors 9(), 2016
PMID: 26951712
Analysis and dissipation of the antiparasitic agent ivermectin in cattle dung under different field conditions.
Wohde M, Blanckenhorn WU, Floate KD, Lahr J, Lumaret JP, Römbke J, Scheffczyk A, Tixier T, Düring RA., Environ Toxicol Chem 35(8), 2016
PMID: 27100922
New test strategy for dung beetles during the authorization process of parasiticides.
Adler N, Bachmann J, Römbke J., Integr Environ Assess Manag 9(3), 2013
PMID: 23325499
Are the parasiticidal avermectins resistant to dissipation in the environment? The case of eprinomectin.
Litskas VD, Karamanlis XN, Batzias GC, Tsiouris SE., Environ Int 60(), 2013
PMID: 24013019
A review on the toxicity and non-target effects of macrocyclic lactones in terrestrial and aquatic environments.
Lumaret JP, Errouissi F, Floate K, Römbke J, Wardhaugh K., Curr Pharm Biotechnol 13(6), 2012
PMID: 22039795
Fate and effects of ivermectin on soil invertebrates in terrestrial model ecosystems.
Förster B, Boxall A, Coors A, Jensen J, Liebig M, Pope L, Moser T, Römbke J., Ecotoxicology 20(1), 2011
PMID: 21086159
Semifield assessment of the runoff potential and environmental risk of the parasiticide drug ivermectin under Mediterranean conditions.
Fernández C, Porcel MA, Alonso A, San Andrés M, Tarazona JV., Environ Sci Pollut Res Int 18(7), 2011
PMID: 21373858
Introduction to the special issue on environmental risk assessment of pharmaceuticals.
Knacker T, Metcalfe C., Integr Environ Assess Manag 6 Suppl(), 2010
PMID: 20821716

117 References

Daten bereitgestellt von Europe PubMed Central.


AUTHOR UNKNOWN, 0
Solubility excipient classification gradient maps
Avdeef, Pharmacol Res 24(), 2007
Effects of residues of certain anthelmintics in bovine manure on Onthophagus gazella, a non-target organism
Blume, Southwest Entomol 2(), 1976

Boelsterli, 2003
Effects of sulfachlorpyridazine in MS.3-arable land: a multispecies soil system for assessing the environmental fate and effects of veterinary medicines.
Boleas S, Alonso C, Pro J, Babin MM, Fernandez C, Carbonell G, Tarazona JV., Environ. Toxicol. Chem. 24(4), 2005
PMID: 15839554

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0
Veterinary medicines in the environment.
Boxall AB, Fogg LA, Blackwell PA, Kay P, Pemberton EJ, Croxford A., Rev Environ Contam Toxicol 180(), 2004
PMID: 14561076
A screening level index for assessing the impacts of veterinary medicines on dung flies.
Boxall AB, Sherratt TN, Pudner V, Pope LJ., Environ. Sci. Technol. 41(7), 2007
PMID: 17438826
Assessing effects of the pharmaceutical ivermectin on meiobenthic communities using freshwater microcosms
Brinke, Aquat Toxicol (), 2010
Ivermectin: a potent new antiparasitic agent.
Campbell WC, Fisher MH, Stapley EO, Albers-Schonberg G, Jacob TA., Science 221(4613), 1983
PMID: 6308762
Metabolic disposition of ivermectin in tissues of cattle, sheep, and rats.
Chiu SH, Sestokas E, Taub R, Buhs RP, Green M, Sestokas R, Vandenheuvel WJ, Arison BH, Jacob TA., Drug Metab. Dispos. 14(5), 1986
PMID: 2876867
Metabolic disposition of ivermectin in swine.
Chiu SHL, Sestokas E, Taub R, Green ML, Baylis FP, Jacob TA, Lu AYH., J. Agric. Food Chem. 38(11), 1990
PMID: IND91004558
Effect of diet on the excretion profile of ivermectin in cattle faeces.
Cook DF, Dadour IR, Ali DN., Int. J. Parasitol. 26(3), 1996
PMID: 8786219
Interspecific relationships among soil invertebrates influence pollutant effects of phenanthrene.
Cortet J, Joffre R, Elmholt S, Coeurdassier M, Scheifler R, Krogh PH., Environ. Toxicol. Chem. 25(1), 2006
PMID: 16494232
Environmental risk from dissolved ivermectin to marine organisms
Davies, Aquaculture 158(), 1997
Actions of dihydroavermectin B1a on insect muscle.
Duce IR, Scott RH., Br. J. Pharmacol. 85(2), 1985
PMID: 2411323

Dybas, 1989

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0
Environmental impact of avermectins
Edwards, Rev Environ Contam Toxicol 171(), 2001
Chronic toxicity of ivermectin to the benthic invertebrates Chironomus riparius and Lumbriculus variegatus
Egeler, J Soils Sediment 10(), 2010

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0
Membrane-water partitioning, membrane permeability, and baseline toxicity of the parasiticides ivermectin, albendazole, and morantel.
Escher BI, Berger C, Bramaz N, Kwon JH, Richter M, Tsinman O, Avdeef A., Environ. Toxicol. Chem. 27(4), 2008
PMID: 18333693
Pharmacokinetic profile of ivermectin in cattle dung excretion, and its associated environmental hazard
Fernandez, Soil Sediment Contam 18(), 2009

Fink, 1988
Off-target effects of ivermectin on insects and on dung degradation in southern Alberta, Canada
Floate, B Entomol Res 88(), 1998
Does a repellent effect contribute to reduced levels of insect activity in dung from cattle treated with ivermectin?
Floate, B Entomol Res 88(), 1998
Fecal residues of veterinary parasiticides: nontarget effects in the pasture environment.
Floate KD, Wardhaugh KG, Boxall AB, Sherratt TN., Annu. Rev. Entomol. 50(), 2005
PMID: 15471531

AUTHOR UNKNOWN, 0
Fate and effects of ivermectin on soil invertebrates in terrestrial model ecosystems
Förster, Ecotoxicology (), 2010
Effects of the parasiticide ivermectin on the cladoceran Daphnia magna and the green alga Pseudokirchneriella subcapitata.
Garric J, Vollat B, Duis K, Pery A, Junker T, Ramil M, Fink G, Ternes TA., Chemosphere 69(6), 2007
PMID: 17624408

Giddings, 2002
Use of ivermectin in marine fish farms: some concerns
Grant, Mar Pollut Bull 36(), 1998
Effect of the antiparasitic drugs fenbendazole and ivermectin on the soil nematode Pristionchus maupasi.
Gronvold J, Svendsen TS, Kraglund HO, Bresciani J, Monrad J., Vet. Parasitol. 124(1-2), 2004
PMID: 15350664
The effect of ivermectin on the survival, behaviour and cocoon production of the earthworm Eisenia fetida
Gunn, Pedobiologia 38(), 1994
The environmental impact of the use of ivermectin: environmental effects and fate
Halley, Chemosphere 18(), 1989

Halley, 1992

Halley, 1989
Occurrence, fate and effects of pharmaceutical substances in the environment--a review.
Halling-Sorensen B, Nors Nielsen S, Lanzky PF, Ingerslev F, Holten Lutzhoft HC, Jorgensen SE., Chemosphere 36(2), 1998
PMID: 9569937
Toxicity of four veterinary parasiticides on larvae of the dung beetle Aphodius constans in the laboratory.
Hempel H, Scheffczyk A, Schallnass HJ, Lumaret JP, Alvinerie M, Rombke J., Environ. Toxicol. Chem. 25(12), 2006
PMID: 17220084

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0
Toxicity and pathological effects of orally administered ivermectin in Atlantic, chinook, and coho salmon and steelhead trout
Johnson, Dis Aquat Org 17(), 1993
Investigations of the toxicity of ivermectin for salmonids
Kilmartin, B Eur Assoc Fish Pat 17(), 1996
A systematic approach for evaluating the quality of experimental toxicological and ecotoxicological data.
Klimisch HJ, Andreae M, Tillmann U., Regul. Toxicol. Pharmacol. 25(1), 1997
PMID: 9056496
Ring-testing and field-validation of a terrestrial model ecosystem (TME)-An instrument for testing potentially harmful substances: Conceptual approach and study design
Knacker, Ecotoxicology 13(), 2004
Veterinary parasiticides-Are they posing an environmental risk?
Kolar, Sloven Vet Res 43(), 2006

Koschorreck, 2006

Koschorreck, 2004

AUTHOR UNKNOWN, 0
Analysis of the dissipation kinetics of ivermectin at different temperatures and in four different soils.
Krogh KA, Jensen GG, Schneider MK, Fenner K, Halling-Sorensen B., Chemosphere 75(8), 2009
PMID: 19217643
Sorption and mobility of ivermectin in different soils.
Krogh KA, Soeborg T, Brodin B, Halling-Sorensen B., J. Environ. Qual. 37(6), 2008
PMID: 18948473
Changes in the structure of dung insect communities after ivermectin usage in a grassland ecosystem. I. Impact of ivermectin under drought conditions
Krüger, Acta Oecol 19(), 1998
Changes in the structure of dung insect communities after ivermectin usage in a grassland ecosystem. II. Impact of ivermectin under high rainfall conditions
Krüger, Acta Oecol 19(), 1998
Merck's new drug free to WHO for river blindness programme.
Lindley D., Nature 329(6142), 1987
PMID: 3670379
Environmental fate of pharmaceuticals in water/sediment systems.
Loffler D, Rombke J, Meller M, Ternes TA., Environ. Sci. Technol. 39(14), 2005
PMID: 16082949
New screening test to predict the potential impact of ivermectin-contaminated cattle dung on dung beetles.
Lumaret JP, Alvinerie M, Hempel H, Schallnass HJ, Claret D, Rombke J., Vet. Res. 38(1), 2006
PMID: 17074292

AUTHOR UNKNOWN, 0
Treating cattle with ivermectin: effects on the fauna and decomposition of dung pats
Madsen, J Appl Ecol 27(), 1990

Millennium, 2003

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

Õmura, 2002
Ivermectin: 25 years and still going strong
Õmura, Int J Antimicrob Agric 31(), 2008
Leaching behaviour of pharmaceuticals in soil-testing-systems: a part of an environmental risk assessment for groundwater protection.
Oppel J, Broll G, Loffler D, Meller M, Rombke J, Ternes T., Sci. Total Environ. 328(1-3), 2004
PMID: 15207589

AUTHOR UNKNOWN, 0
Environmental fate of the anthelmintic ivermectin in an aerobic sediment/water system.
Prasse C, Loffler D, Ternes TA., Chemosphere 77(10), 2009
PMID: 19846198

Rohrer, 1995
Lethal and sublethal toxic effects of a test chemical (ivermectin) on the yellow dung fly (Scathophaga stercoraria) based on a standardized international ring test.
Rombke J, Floate KD, Jochmann R, Schafer MA, Puniamoorthy N, Knabe S, Lehmhus J, Rosenkranz B, Scheffczyk A, Schmidt T, Sharples A, Blanckenhorn WU., Environ. Toxicol. Chem. 28(10), 2009
PMID: 19432504
Effects of the parasiticide ivermectin on the structure and function of dung and soil invertebrate communities in the field (Madrid, Spain)
Römbke, Appl Soil Ecol (), 2010
Results of an international ring test with the dung fly Musca autumnalis in support of a new OECD test guideline
Römbke, Sci Total Environ (), 2010
Effects of the veterinary pharmaceutical ivermectin on soil invertebrates in laboratory tests.
Rombke J, Krogh KA, Moser T, Scheffczyk A, Liebig M., Arch. Environ. Contam. Toxicol. 58(2), 2009
PMID: 19882295

AUTHOR UNKNOWN, 0
Assessment of the environmental fate and effects of ivermectin in aquatic mesocosms.
Sanderson H, Laird B, Pope L, Brain R, Wilson C, Johnson D, Bryning G, Peregrine AS, Boxall A, Solomon K., Aquat. Toxicol. 85(4), 2007
PMID: 17963854
Recommendations on the environmental risk assessment of pharmaceuticals-Effect characterization
Schmitt, Integ Environ Assess Manag 6(), 2010
Selecting scenarios to assess exposure of surface waters to veterinary medicines in Europe.
Schneider MK, Stamm C, Fenner K., Environ. Sci. Technol. 41(13), 2007
PMID: 17695913

Shoop, 2002

AUTHOR UNKNOWN, 0
Ivermectin excreted in cattle dung after subcutaneous injection or pour-on treatment: Concentrations and impact on dung fauna
Sommer, B Entomol Res 82(), 1992

Steel, 2002
Avermectins in insect control and biology: A review
Strong, B Entomol Res 77(), 1987
Some effects of ivermectin on the yellow dung fly
Strong, Scathophaga stercoraria. Vet Parasitol 48(), 1993
Effects of ivermectin and doramectin faecal residues on the invertebrate colonization of cattle dung.
Suarez VH, Lifschitz AL, Sallovitz JM, Lanusse CE., J. Appl. Entomol. 127(8), 2003
PMID: IND43630621
Field effects of ivermectin and fenbendazole on earthworm populations and the disappearance of dung pats from bolus-treated cattle.
Svendsen TS, Gronvold J, Holter P, Sommer C., Agric., Ecosyst. Environ., Appl. Soil Ecol. 24(3), 2003
PMID: IND43622011
Targeting the environmental risk assessment of pharmaceuticals: facts and fantasies
Tarazona, Integ Environ Assess Manag 6(), 2010

[USEPA], 1975
Animal drugs, feeds, and related products; ivermectin injection. Department of Health and Human Services
[USFDA], Fed Reg 51(), 1986

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0
Bioconcentration and depuration of avermectin B1a in the bluegill sunfish
Van, Environ Toxicol Chem 15(), 1996

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

Wislocki, 1989
Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Quellen

PMID: 20821718
PubMed | Europe PMC

Suchen in

Google Scholar