Genomewide expression analysis in amino acid-producing bacteria using DNA microarrays

Polen T, Wendisch VF (2004)
Applied Biochemistry and Biotechnology 118(1-3): 215-232.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Abstract / Bemerkung
DNA microarray technology has become an important research tool for biotechnology and microbiology. It is now possible to characterize genetic diversity and gene expression in a genomewide manner. DNA microarrays have been applied extensively to study the biology of many bacteria including Escherichia coli, but only recently have they been developed for the Grampositive Corynebacterium glutamicium. Both bacteria are widely used for biotechnological amino acid production. In this article, in addition to the design and generation of microarrays as well as their use in hybridization experiments and subsequent data analysis, we describe recent applications of DNA microarray technology regarding amino acid production in C. glutamicum and E. coli. We also discuss the impact of functional genomics studies on fundamental as well as applied aspects of amino acid production with C. glutamicum and E. coli.
Stichworte
combined transcriptome; salmonella-typhimurium; gene-expression; messenger-rna; DNA chips; genomewide gene expression analysis; cluster analysis; DNA microarrays; global regulatory mechanisms; corynebacterium glutamicum; amino acid production; escherichia coli; escherichia-coli k-12; corynebacterium-glutamicum atcc-13032; responsive regulatory protein; density oligonucleotide arrays; acetate metabolism; nitrogen limitation
Erscheinungsjahr
2004
Zeitschriftentitel
Applied Biochemistry and Biotechnology
Band
118
Ausgabe
1-3
Seite(n)
215-232
ISSN
0273-2289
Page URI
https://pub.uni-bielefeld.de/record/1895226

Zitieren

Polen T, Wendisch VF. Genomewide expression analysis in amino acid-producing bacteria using DNA microarrays. Applied Biochemistry and Biotechnology. 2004;118(1-3):215-232.
Polen, T., & Wendisch, V. F. (2004). Genomewide expression analysis in amino acid-producing bacteria using DNA microarrays. Applied Biochemistry and Biotechnology, 118(1-3), 215-232. doi:10.1385/abab:118:1-3:215
Polen, T., and Wendisch, V. F. (2004). Genomewide expression analysis in amino acid-producing bacteria using DNA microarrays. Applied Biochemistry and Biotechnology 118, 215-232.
Polen, T., & Wendisch, V.F., 2004. Genomewide expression analysis in amino acid-producing bacteria using DNA microarrays. Applied Biochemistry and Biotechnology, 118(1-3), p 215-232.
T. Polen and V.F. Wendisch, “Genomewide expression analysis in amino acid-producing bacteria using DNA microarrays”, Applied Biochemistry and Biotechnology, vol. 118, 2004, pp. 215-232.
Polen, T., Wendisch, V.F.: Genomewide expression analysis in amino acid-producing bacteria using DNA microarrays. Applied Biochemistry and Biotechnology. 118, 215-232 (2004).
Polen, T., and Wendisch, Volker F. “Genomewide expression analysis in amino acid-producing bacteria using DNA microarrays”. Applied Biochemistry and Biotechnology 118.1-3 (2004): 215-232.

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