Functional analysis of a light-responsive plant bZIP transcriptional regulator

Feldbrügge M, Sprenger M, Dinkelbach M, Yazaki K, Harter K, Weisshaar B (1994)
The Plant Cell 6(11): 1607-1621.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Feldbrügge, M.; Sprenger, M.; Dinkelbach, M.; Yazaki, K.; Harter, K.; Weisshaar, BerndUniBi
Abstract / Bemerkung
Common plant regulatory factor 1 (CPRF1) is a parsley basic region/leucine zipper (bZIP) transcription factor that recognizes specific nucleotide sequences containing ACGT cores. Such a sequence is contained within LRU1, the composite light regulatory unit that is necessary and sufficient for light-dependent activity of the parsley chalcone synthase (CHS) promoter. After light treatment of both etiolated and green seedlings, CPRF1 mRNA levels increased prior to CHS mRNA accumulation. The change in CPRF1 mRNA leads to a light-responsive increase in CPRF1 protein. Transient expression analysis in parsley protoplasts using the CPRF1 promoter fused to the beta-glucuronidase (GUS) open reading frame indicated that light-dependent CPRF1 mRNA accumulation was under transcriptional control. The 5' untranslated region of the CPRF1 gene includes a cis-acting nucleotide sequence that contains two ACGT elements at a distance of 12 bp between their palindromic centers. This feature is reminiscent of as-1 and octopine synthase (ocs) elements identified in promoters from plant pathogens. This double ACGT Element element, designated dACECPRF1, stimulated transcription when placed 5' to a heterologous core promoter. CPRF1 bound to dACECPRF1 DNA as well as to the ACGT element from the CHS promoter in vitro. Cotransfection experiments demonstrated that CPRF1 interacts with these elements in vivo and that overexpression of CPRF1 actually reduced light-dependent transcription from the CHS promoter. CPRF1 thus appears to contribute to the regulation of the CPRF1 gene and to interfere with the activities of light-regulated promoters.
The Plant Cell
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Feldbrügge M, Sprenger M, Dinkelbach M, Yazaki K, Harter K, Weisshaar B. Functional analysis of a light-responsive plant bZIP transcriptional regulator. The Plant Cell. 1994;6(11):1607-1621.
Feldbrügge, M., Sprenger, M., Dinkelbach, M., Yazaki, K., Harter, K., & Weisshaar, B. (1994). Functional analysis of a light-responsive plant bZIP transcriptional regulator. The Plant Cell, 6(11), 1607-1621.
Feldbrügge, M., Sprenger, M., Dinkelbach, M., Yazaki, K., Harter, K., and Weisshaar, B. (1994). Functional analysis of a light-responsive plant bZIP transcriptional regulator. The Plant Cell 6, 1607-1621.
Feldbrügge, M., et al., 1994. Functional analysis of a light-responsive plant bZIP transcriptional regulator. The Plant Cell, 6(11), p 1607-1621.
M. Feldbrügge, et al., “Functional analysis of a light-responsive plant bZIP transcriptional regulator”, The Plant Cell, vol. 6, 1994, pp. 1607-1621.
Feldbrügge, M., Sprenger, M., Dinkelbach, M., Yazaki, K., Harter, K., Weisshaar, B.: Functional analysis of a light-responsive plant bZIP transcriptional regulator. The Plant Cell. 6, 1607-1621 (1994).
Feldbrügge, M., Sprenger, M., Dinkelbach, M., Yazaki, K., Harter, K., and Weisshaar, Bernd. “Functional analysis of a light-responsive plant bZIP transcriptional regulator”. The Plant Cell 6.11 (1994): 1607-1621.

48 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

RSM1, an Arabidopsis MYB protein, interacts with HY5/HYH to modulate seed germination and seedling development in response to abscisic acid and salinity.
Yang B, Song Z, Li C, Jiang J, Zhou Y, Wang R, Wang Q, Ni C, Liang Q, Chen H, Fan LM., PLoS Genet 14(12), 2018
PMID: 30566447
An intracellular antifreeze protein from an Antarctic microalga that responds to various environmental stresses.
Gwak Y, Jung W, Lee Y, Kim JS, Kim CG, Ju JH, Song C, Hyun JK, Jin E., FASEB J 28(11), 2014
PMID: 25114178
Plant bZIP transcription factors responsive to pathogens: a review.
Alves MS, Dadalto SP, Gonçalves AB, De Souza GB, Barros VA, Fietto LG., Int J Mol Sci 14(4), 2013
PMID: 23574941
Expression analysis of anthocyanin regulatory genes in response to different light qualities in Arabidopsis thaliana.
Cominelli E, Gusmaroli G, Allegra D, Galbiati M, Wade HK, Jenkins GI, Tonelli C., J Plant Physiol 165(8), 2008
PMID: 17766004
An unidentified ultraviolet-B-specific photoreceptor mediates transcriptional activation of the cyclobutane pyrimidine dimer photolyase gene in plants.
Ioki M, Takahashi S, Nakajima N, Fujikura K, Tamaoki M, Saji H, Kubo A, Aono M, Kanna M, Ogawa D, Fukazawa J, Oda Y, Yoshida S, Watanabe M, Hasezawa S, Kondo N., Planta 229(1), 2008
PMID: 18825406
Light-regulated transcriptional networks in higher plants.
Jiao Y, Lau OS, Deng XW., Nat Rev Genet 8(3), 2007
PMID: 17304247
bZIP10-LSD1 antagonism modulates basal defense and cell death in Arabidopsis following infection.
Kaminaka H, Näke C, Epple P, Dittgen J, Schütze K, Chaban C, Holt BF, Merkle T, Schäfer E, Harter K, Dangl JL., EMBO J 25(18), 2006
PMID: 16957775
Effect of copy number and spacing of the ACGT and GT cis elements on transient expression of minimal promoter in plants.
Mehrotra R, Kiran K, Chaturvedi CP, Ansari SA, Lodhi N, Sawant S, Tuli R., J Genet 84(2), 2005
PMID: 16131718
Comparative analysis of the plant mRNA-destabilizing element, DST, in mammalian and tobacco cells.
Feldbrügge M, Arizti P, Sullivan ML, Zamore PD, Belasco JG, Green PJ., Plant Mol Biol 49(2), 2002
PMID: 11999376
Targets of AtWRKY6 regulation during plant senescence and pathogen defense.
Robatzek S, Somssich IE., Genes Dev 16(9), 2002
PMID: 12000796
Bus, a bushy Arabidopsis CYP79F1 knockout mutant with abolished synthesis of short-chain aliphatic glucosinolates.
Reintanz B, Lehnen M, Reichelt M, Gershenzon J, Kowalczyk M, Sandberg G, Godde M, Uhl R, Palme K., Plant Cell 13(2), 2001
PMID: 11226190
A novel dark-inducible protein, LeDI-2, and its involvement in root-specific secondary metabolism in Lithospermum erythrorhizon.
Yazaki K, Matsuoka H, Shimomura K, Bechthold A, Sato F., Plant Physiol 125(4), 2001
PMID: 11299363
Identification of the Arabidopsis thaliana flavonoid 3'-hydroxylase gene and functional expression of the encoded P450 enzyme.
Schoenbohm C, Martens S, Eder C, Forkmann G, Weisshaar B., Biol Chem 381(8), 2000
PMID: 11030432
Transcriptional repression by AtMYB4 controls production of UV-protecting sunscreens in Arabidopsis.
Jin H, Cominelli E, Bailey P, Parr A, Mehrtens F, Jones J, Tonelli C, Weisshaar B, Martin C., EMBO J 19(22), 2000
PMID: 11080161
Nuclear import of the parsley bZIP transcription factor CPRF2 is regulated by phytochrome photoreceptors.
Kircher S, Wellmer F, Nick P, Rügner A, Schäfer E, Harter K., J Cell Biol 144(2), 1999
PMID: 9922448
Phenylpropanoid biosynthesis and its regulation.
Weisshaar B, Jenkins GI., Curr Opin Plant Biol 1(3), 1998
PMID: 10066590
Schwechheimer C, Zourelidou M, Bevan MW., Annu Rev Plant Physiol Plant Mol Biol 49(), 1998
PMID: 15012230
Arguello-Astorga G, Herrera-Estrella L., Annu Rev Plant Physiol Plant Mol Biol 49(), 1998
PMID: 15012245
Knock-out mutants from an En-1 mutagenized Arabidopsis thaliana population generate phenylpropanoid biosynthesis phenotypes.
Wisman E, Hartmann U, Sagasser M, Baumann E, Palme K, Hahlbrock K, Saedler H, Weisshaar B., Proc Natl Acad Sci U S A 95(21), 1998
PMID: 9770503
Cooperative DNA binding and sequence discrimination by the Opaque2 bZIP factor.
Yunes JA, Vettore AL, da Silva MJ, Leite A, Arruda P., Plant Cell 10(11), 1998
PMID: 9811800
The activation domain of the maize transcription factor Opaque-2 resides in a single acidic region.
Schmitz D, Lohmer S, Salamini F, Thompson RD., Nucleic Acids Res 25(4), 1997
PMID: 9016625
The transcriptional regulator CPRF1: expression analysis and gene structure.
Feldbrügge M, Hahlbrock K, Weisshaar B., Mol Gen Genet 251(6), 1996
PMID: 8757392
Oligopeptide elicitor-mediated defense gene activation in cultured parsley cells.
Hahlbrock K, Scheel D, Logemann E, Nürnberger T, Parniske M, Reinold S, Sacks WR, Schmelzer E., Proc Natl Acad Sci U S A 92(10), 1995
PMID: 7753777
Nucleotide sequence of a cDNA from Lithospermum erythrorhizon homologous to PR-1 of parsley.
Yazaki K, Bechthold A, Tabata M., Plant Physiol 108(3), 1995
PMID: 7630965
The G-box: a ubiquitous regulatory DNA element in plants bound by the GBF family of bZIP proteins.
Menkens AE, Schindler U, Cashmore AR., Trends Biochem Sci 20(12), 1995
PMID: 8571452

40 References

Daten bereitgestellt von Europe PubMed Central.

Polyubiquitin gene expression and structural properties of the ubi4-2 gene in Petroselinum crispum.
Kawalleck P, Somssich IE, Feldbrugge M, Hahlbrock K, Weisshaar B., Plant Mol. Biol. 21(4), 1993
PMID: 8383552
Plant bZIP protein DNA binding specificity.
Izawa T, Foster R, Chua NH., J. Mol. Biol. 230(4), 1993
PMID: 8487298
OHP1: a maize basic domain/leucine zipper protein that interacts with opaque2.
Pysh LD, Aukerman MJ, Schmidt RJ., Plant Cell 5(2), 1993
PMID: 8453304
Opaque-2 is a transcriptional activator that recognizes a specific target site in 22-kD zein genes.
Schmidt RJ, Ketudat M, Aukerman MJ, Hoschek G., Plant Cell 4(6), 1992
PMID: 1392590
Transcription factors: structural families and principles of DNA recognition.
Pabo CO, Sauer RT., Annu. Rev. Biochem. 61(), 1992
PMID: 1497306
A cDNA clone encoding HBP-1b homologue in Arabidopsis thaliana.
Kawata T, Imada T, Shiraishi H, Okada K, Shimura Y, Iwabuchi M., Nucleic Acids Res. 20(5), 1992
PMID: 1549479
Analysis of rice Act1 5' region activity in transgenic rice plants.
Zhang W, McElroy D, Wu R., Plant Cell 3(11), 1991
PMID: 1821763
Parsley protoplasts retain differential responsiveness to u.v. light and fungal elicitor.
Dangl JL, Hauffe KD, Lipphardt S, Hahlbrock K, Scheel D., EMBO J. 6(9), 1987
PMID: 16453792
A comprehensive set of sequence analysis programs for the VAX.
Devereux J, Haeberli P, Smithies O., Nucleic Acids Res. 12(1 Pt 1), 1984
PMID: 6546423
Site-specific mutations alter in vitro factor binding and change promoter expression pattern in transgenic plants.
Lam E, Benfey PN, Gilmartin PM, Fang RX, Chua NH., Proc. Natl. Acad. Sci. U.S.A. 86(20), 1989
PMID: 2813365
The ocs-element is a component of the promoters of several T-DNA and plant viral genes.
Bouchez D, Tokuhisa JG, Llewellyn DJ, Dennis ES, Ellis JG., EMBO J. 8(13), 1989
PMID: 2591372
Eukaryotic transcriptional regulatory proteins.
Johnson PF, McKnight SL., Annu. Rev. Biochem. 58(), 1989
PMID: 2673023
Scissors-grip model for DNA recognition by a family of leucine zipper proteins.
Vinson CR, Sigler PB, McKnight SL., Science 246(4932), 1989
PMID: 2683088
Inducible in vivo DNA footprints define sequences necessary for UV light activation of the parsley chalcone synthase gene.
Schulze-Lefert P, Dangl JL, Becker-Andre M, Hahlbrock K, Schulz W., EMBO J. 8(3), 1989
PMID: 2566481
The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins.
Landschulz WH, Johnson PF, McKnight SL., Science 240(4860), 1988
PMID: 3289117
An evolutionarily conserved protein binding sequence upstream of a plant light-regulated gene.
Giuliano G, Pichersky E, Malik VS, Timko MP, Scolnik PA, Cashmore AR., Proc. Natl. Acad. Sci. U.S.A. 85(19), 1988
PMID: 2902624
A plant leucine zipper protein that recognizes an abscisic acid response element.
Guiltinan MJ, Marcotte WR Jr, Quatrano RS., Science 250(4978), 1990
PMID: 2145628
The maize regulatory locus Opaque-2 encodes a DNA-binding protein which activates the transcription of the b-32 gene.
Lohmer S, Maddaloni M, Motto M, Di Fonzo N, Hartings H, Salamini F, Thompson RD., EMBO J. 10(3), 1991
PMID: 2001677
The Viviparous-1 developmental gene of maize encodes a novel transcriptional activator.
McCarty DR, Hattori T, Carson CB, Vasil V, Lazar M, Vasil IK., Cell 66(5), 1991
PMID: 1889090
Plant bZIP proteins gather at ACGT elements.
Foster R, Izawa T, Chua NH., FASEB J. 8(2), 1994
PMID: 8119490
Isolation of a maize bZIP protein subfamily: candidates for the ocs-element transcription factor.
Foley RC, Grossman C, Ellis JG, Llewellyn DJ, Dennis ES, Peacock WJ, Singh KB., Plant J. 3(5), 1993
PMID: 8374617
The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation.
Angel P, Karin M., Biochim. Biophys. Acta 1072(2-3), 1991
PMID: 1751545
BPF-1, a pathogen-induced DNA-binding protein involved in the plant defense response.
da Costa e Silva O, Klein L, Schmelzer E, Trezzini GF, Hahlbrock K., Plant J. 4(1), 1993
PMID: 8220470


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