Cyclooxygenase-2 is a neuronal target gene of NF-kB

Kaltschmidt B, Linker RA, Deng J, Kaltschmidt C (2002)
BMC Mol Biol 3 3(1): 16.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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DOI
Autor*in
Kaltschmidt, BarbaraUniBi; Linker, R. A.; Deng, J.; Kaltschmidt, ChristianUniBi
Einrichtung
Fakultät für Biologie > Zellbiologie der Tiere
Erscheinungsjahr
2002
Zeitschriftentitel
BMC Mol Biol 3
Band
3
Ausgabe
1
Art.-Nr.
16
ISSN
1471-2199
Page URI
https://pub.uni-bielefeld.de/record/1865567

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Kaltschmidt B, Linker RA, Deng J, Kaltschmidt C. Cyclooxygenase-2 is a neuronal target gene of NF-kB. BMC Mol Biol 3. 2002;3(1): 16.
Kaltschmidt, B., Linker, R. A., Deng, J., & Kaltschmidt, C. (2002). Cyclooxygenase-2 is a neuronal target gene of NF-kB. BMC Mol Biol 3, 3(1), 16. https://doi.org/10.1186/1471-2199-3-16
Kaltschmidt, Barbara, Linker, R. A., Deng, J., and Kaltschmidt, Christian. 2002. “Cyclooxygenase-2 is a neuronal target gene of NF-kB”. BMC Mol Biol 3 3 (1): 16.
Kaltschmidt, B., Linker, R. A., Deng, J., and Kaltschmidt, C. (2002). Cyclooxygenase-2 is a neuronal target gene of NF-kB. BMC Mol Biol 3 3:16.
Kaltschmidt, B., et al., 2002. Cyclooxygenase-2 is a neuronal target gene of NF-kB. BMC Mol Biol 3, 3(1): 16.
B. Kaltschmidt, et al., “Cyclooxygenase-2 is a neuronal target gene of NF-kB”, BMC Mol Biol 3, vol. 3, 2002, : 16.
Kaltschmidt, B., Linker, R.A., Deng, J., Kaltschmidt, C.: Cyclooxygenase-2 is a neuronal target gene of NF-kB. BMC Mol Biol 3. 3, : 16 (2002).
Kaltschmidt, Barbara, Linker, R. A., Deng, J., and Kaltschmidt, Christian. “Cyclooxygenase-2 is a neuronal target gene of NF-kB”. BMC Mol Biol 3 3.1 (2002): 16.

46 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Molecular hydrogen alleviates asphyxia-induced neuronal cyclooxygenase-2 expression in newborn pigs.
Varga V, Németh J, Oláh O, Tóth-Szűki V, Kovács V, Remzső G, Domoki F., Acta Pharmacol Sin 39(8), 2018
PMID: 29565041
Aspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling.
Henry WS, Laszewski T, Tsang T, Beca F, Beck AH, McAllister SS, Toker A., Cancer Res 77(3), 2017
PMID: 27940576
Negative regulatory roles of ORMDL3 in the FcεRI-triggered expression of proinflammatory mediators and chemotactic response in murine mast cells.
Bugajev V, Halova I, Draberova L, Bambouskova M, Potuckova L, Draberova H, Paulenda T, Junyent S, Draber P., Cell Mol Life Sci 73(6), 2016
PMID: 26407610
TNFα up-regulates COX-2 in chronic progressive nephropathy through nuclear accumulation of RelB and NF-κB2.
Qiu J, Yuan H, Chen S, Zhou Y, Song D, Chen R., Arch Physiol Biochem 122(2), 2016
PMID: 26824492
Oxidative Stress and Nuclear Factor κB (NF-κB) Increase Peritoneal Filtration and Contribute to Ascites Formation in Nephrotic Syndrome.
Udwan K, Brideau G, Fila M, Edwards A, Vogt B, Doucet A., J Biol Chem 291(21), 2016
PMID: 27033704
Effects of Oxidative Stress and Testosterone on Pro-Inflammatory Signaling in a Female Rat Dopaminergic Neuronal Cell Line.
Holmes S, Singh M, Su C, Cunningham RL., Endocrinology 157(7), 2016
PMID: 27167771
Characterization of Eicosanoids Produced by Adipocyte Lipolysis: IMPLICATION OF CYCLOOXYGENASE-2 IN ADIPOSE INFLAMMATION.
Gartung A, Zhao J, Chen S, Mottillo E, VanHecke GC, Ahn YH, Maddipati KR, Sorokin A, Granneman J, Lee MJ., J Biol Chem 291(31), 2016
PMID: 27246851
HSP90 Inhibition Suppresses PGE2 Production via Modulating COX-2 and 15-PGDH Expression in HT-29 Colorectal Cancer Cells.
Mohammadi A, Yaghoobi MM, Gholamhoseinian Najar A, Kalantari-Khandani B, Sharifi H, Saravani M., Inflammation 39(3), 2016
PMID: 27075590
Breast Cancer Genetic and Molecular Subtype Impacts Response to Omega-3 Fatty Acid Ethyl Esters.
Chen CH, Fabian C, Hursting S, deGraffenried LA., Nutr Cancer 68(6), 2016
PMID: 27367296
Neuronal Gene Targets of NF-κB and Their Dysregulation in Alzheimer's Disease.
Snow WM, Albensi BC., Front Mol Neurosci 9(), 2016
PMID: 27881951
Spontaneous Glutamatergic Synaptic Activity Regulates Constitutive COX-2 Expression in Neurons: OPPOSING ROLES FOR THE TRANSCRIPTION FACTORS CREB (cAMP RESPONSE ELEMENT BINDING) PROTEIN AND Sp1 (STIMULATORY PROTEIN-1).
Hewett SJ, Shi J, Gong Y, Dhandapani K, Pilbeam C, Hewett JA., J Biol Chem 291(53), 2016
PMID: 27875294
Species differential regulation of COX2 can be described by an NFκB-dependent logic AND gate.
Nguyen LK, Cavadas MA, Kholodenko BN, Frank TD, Cheong A., Cell Mol Life Sci 72(12), 2015
PMID: 25697863
Endogenous 2-Arachidonoylglycerol Alleviates Cyclooxygenases-2 Elevation-Mediated Neuronal Injury From SO2 Inhalation via PPARγ Pathway.
Li B, Chen M, Guo L, Yun Y, Li G, Sang N., Toxicol Sci 147(2), 2015
PMID: 26209559
NF-KappaB in Long-Term Memory and Structural Plasticity in the Adult Mammalian Brain.
Kaltschmidt B, Kaltschmidt C., Front Mol Neurosci 8(), 2015
PMID: 26635522
The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes.
König HG, Coughlan KS, Kinsella S, Breen BA, Prehn JH., Neurobiol Dis 70(), 2014
PMID: 24956542
Combined effect of dehydroxymethylepoxyquinomicin and gemcitabine in a mouse model of liver metastasis of pancreatic cancer.
Suzuki K, Aiura K, Matsuda S, Itano O, Takeuchi O, Umezawa K, Kitagawa Y., Clin Exp Metastasis 30(4), 2013
PMID: 23111540
A chemical complementation approach reveals genes and interactions of flavonoids with other pathways.
Pourcel L, Irani NG, Koo AJ, Bohorquez-Restrepo A, Howe GA, Grotewold E., Plant J 74(3), 2013
PMID: 23360095
Constitutive and tumor necrosis factor-α-induced activation of nuclear factor-κB in adenomyosis and its inhibition by andrographolide.
Li B, Chen M, Liu X, Guo SW., Fertil Steril 100(2), 2013
PMID: 23706331
Minimal NF-κB activity in neurons.
Listwak SJ, Rathore P, Herkenham M., Neuroscience 250(), 2013
PMID: 23872390
Sunitinib enhances neuronal survival in vitro via NF-κB-mediated signaling and expression of cyclooxygenase-2 and inducible nitric oxide synthase.
Sanchez A, Tripathy D, Yin X, Luo J, Martinez JM, Grammas P., J Neuroinflammation 10(), 2013
PMID: 23880112
Sexual differentiation of the gonadotropin surge release mechanism: a new role for the canonical NfκB signaling pathway.
Petersen SL, Krishnan S, Aggison LK, Intlekofer KA, Moura PJ., Front Neuroendocrinol 33(1), 2012
PMID: 21741397
Therapeutic potential of andrographolide for treating endometriosis.
Zheng Y, Liu X, Guo SW., Hum Reprod 27(5), 2012
PMID: 22402211
Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability.
Zhu W, London NR, Gibson CC, Davis CT, Tong Z, Sorensen LK, Shi DS, Guo J, Smith MC, Grossmann AH, Thomas KR, Li DY., Nature 492(7428), 2012
PMID: 23143332
TNF-α potentiates glutamate-induced spinal cord motoneuron death via NF-κB.
Tolosa L, Caraballo-Miralles V, Olmos G, Lladó J., Mol Cell Neurosci 46(1), 2011
PMID: 20849956
Chronic valproate treatment blocks D2-like receptor-mediated brain signaling via arachidonic acid in rats.
Ramadan E, Basselin M, Taha AY, Cheon Y, Chang L, Chen M, Rapoport SI., Neuropharmacology 61(8), 2011
PMID: 21839100
SO(2)-induced neurotoxicity is mediated by cyclooxygenases-2-derived prostaglandin E(2) and its downstream signaling pathway in rat hippocampal neurons.
Sang N, Yun Y, Yao GY, Li HY, Guo L, Li GK., Toxicol Sci 124(2), 2011
PMID: 21873648
Estrogen increases expression of the human prostacyclin receptor within the vasculature through an ERalpha-dependent mechanism.
Turner EC, Kinsella BT., J Mol Biol 396(3), 2010
PMID: 20070947
NF-kappaB induces PGE2-synthesizing enzymes in neurons.
Barakat W, Herrmann O, Baumann B, Schwaninger M., Naunyn Schmiedebergs Arch Pharmacol 380(2), 2009
PMID: 19415240
Antiinflammatory and neuroprotective actions of COX2 inhibitors in the injured brain.
Strauss KI., Brain Behav Immun 22(3), 2008
PMID: 17996418
Triptolide inhibits COX-2 expression and PGE2 release by suppressing the activity of NF-kappaB and JNK in LPS-treated microglia.
Gong Y, Xue B, Jiao J, Jing L, Wang X., J Neurochem 107(3), 2008
PMID: 18761708
HIV-1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in astrocytoma cells through a nuclear factor-kappaB-dependent mechanism.
Alvarez S, Serramía MJ, Fresno M, Muñoz-Fernández MA., Neuromolecular Med 9(2), 2007
PMID: 17627037
Biphasic role of nuclear factor-kappa B on cell survival and COX-2 expression in SOD1 Tg astrocytes after oxygen glucose deprivation.
Lee YS, Song YS, Giffard RG, Chan PH., J Cereb Blood Flow Metab 26(8), 2006
PMID: 16395278
Antioxidant pyrrolidine dithiocarbamate activates Akt-GSK signaling and is neuroprotective in neonatal hypoxia-ischemia.
Nurmi A, Goldsteins G, Närväinen J, Pihlaja R, Ahtoniemi T, Gröhn O, Koistinaho J., Free Radic Biol Med 40(10), 2006
PMID: 16678015
NF-kappaB and COX-2 during oral tumorigenesis and in assessment of minimal residual disease in surgical margins.
Santhi WS, Sebastian P, Varghese BT, Prakash O, Pillai MR., Exp Mol Pathol 81(2), 2006
PMID: 16822500
NF-kappaB functions in the nervous system: from development to disease.
Mémet S., Biochem Pharmacol 72(9), 2006
PMID: 16997282
The role of NF-kappaB in mediating the anti-inflammatory effects of IL-10 in intestinal epithelial cells.
Al-Ashy R, Chakroun I, El-Sabban ME, Homaidan FR., Cytokine 36(1-2), 2006
PMID: 17161612
Differential transcriptional control of the superoxide dismutase-2 kappaB element in neurons and astrocytes.
Mao X, Moerman-Herzog AM, Wang W, Barger SW., J Biol Chem 281(47), 2006
PMID: 17023425
Human immunodeficiency virus type 1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in neuroblastoma cells through a nuclear factor-kappaB and activating protein-1 mediated mechanism.
Alvarez S, Serramía MJ, Fresno M, Muñoz-Fernández M., J Neurochem 94(3), 2005
PMID: 16001969
NFkappaB activates in vivo the synthesis of inducible Cox-2 in the brain.
Nadjar A, Tridon V, May MJ, Ghosh S, Dantzer R, Amédée T, Parnet P., J Cereb Blood Flow Metab 25(8), 2005
PMID: 15758944
Signaling via NF-kappaB in the nervous system.
Kaltschmidt B, Widera D, Kaltschmidt C., Biochim Biophys Acta 1745(3), 2005
PMID: 15993497
Down-regulation of brain nuclear factor-kappa B pathway in the cyclooxygenase-2 knockout mouse.
Rao JS, Langenbach R, Bosetti F., Brain Res Mol Brain Res 139(2), 2005
PMID: 16055227
Nuclear factor-kappaB contributes to infarction after permanent focal ischemia.
Nurmi A, Lindsberg PJ, Koistinaho M, Zhang W, Juettler E, Karjalainen-Lindsberg ML, Weih F, Frank N, Schwaninger M, Koistinaho J., Stroke 35(4), 2004
PMID: 14988572
Gene expression profiling in fetal, aged, and Alzheimer hippocampus: a continuum of stress-related signaling.
Lukiw WJ., Neurochem Res 29(6), 2004
PMID: 15176485
Angiogenic signaling in Alzheimer's disease.
Pogue AI, Lukiw WJ., Neuroreport 15(9), 2004
PMID: 15194884
Gonococcal porin IB activates NF-kappaB in human urethral epithelium and increases the expression of host antiapoptotic factors.
Binnicker MJ, Williams RD, Apicella MA., Infect Immun 72(11), 2004
PMID: 15501771
Microarray analysis of tumor necrosis factor alpha induced gene expression in U373 human glioblastoma cells.
Schwamborn J, Lindecke A, Elvers M, Horejschi V, Kerick M, Rafigh M, Pfeiffer J, Prüllage M, Kaltschmidt B, Kaltschmidt C., BMC Genomics 4(1), 2003
PMID: 14641910

52 References

Daten bereitgestellt von Europe PubMed Central.

Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation.
Liou HC, Sha WC, Scott ML, Baltimore D., Mol. Cell. Biol. 14(8), 1994
PMID: 8035813
Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate.
Zandi E, Chen Y, Karin M., Science 281(5381), 1998
PMID: 9721103
Cyclooxygenase in biology and disease.
Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, Van De Putte LB, Lipsky PE., FASEB J. 12(12), 1998
PMID: 9737710
IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex.
Rothwarf DM, Zandi E, Natoli G, Karin M., Nature 395(6699), 1998
PMID: 9751060
The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta.
Yin MJ, Yamamoto Y, Gaynor RB., Nature 396(6706), 1998
PMID: 9817203
Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis.
Kaltschmidt B, Uherek M, Wellmann H, Volk B, Kaltschmidt C., Proc. Natl. Acad. Sci. U.S.A. 96(16), 1999
PMID: 10430956
Ultrastructural localization of activated NF-kappaB in granule cells of the rat fascia dentata.
Kaltschmidt B, Deller T, Frotscher M, Kaltschmidt C., Neuroreport 11(4), 2000
PMID: 10757530
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity.
Karin M, Ben-Neriah Y., Annu. Rev. Immunol. 18(), 2000
PMID: 10837071
Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex.
May MJ, D'Acquisto F, Madge LA, Glockner J, Pober JS, Ghosh S., Science 289(5484), 2000
PMID: 10968790
Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen.
Tegeder I, Niederberger E, Israr E, Guhring H, Brune K, Euchenhofer C, Grosch S, Geisslinger G., FASEB J. 15(1), 2000
PMID: 11099482
Neuroprotective role for the p50 subunit of NF-kappaB in an experimental model of Huntington's disease.
Yu Z, Zhou D, Cheng G, Mattson MP., J. Mol. Neurosci. 15(1), 2000
PMID: 11211235
The I kappa B kinase: a master regulator of NF-kappa B, innate immunity, and epidermal differentiation.
Delhase M, Karin M., Cold Spring Harb. Symp. Quant. Biol. 64(), 1999
PMID: 11232326
Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity.
Samad TA, Moore KA, Sapirstein A, Billet S, Allchorne A, Poole S, Bonventre JV, Woolf CJ., Nature 410(6827), 2001
PMID: 11260714
COX-2 as a multifunctional neuronal modulator.
Bazan NG., Nat. Med. 7(4), 2001
PMID: 11283664
Retrograde transport of transcription factor NF-kappa B in living neurons.
Wellmann H, Kaltschmidt B, Kaltschmidt C., J. Biol. Chem. 276(15), 2000
PMID: 11096106
Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice.
Andreasson KI, Savonenko A, Vidensky S, Goellner JJ, Zhang Y, Shaffer A, Kaufmann WE, Worley PF, Isakson P, Markowska AL., J. Neurosci. 21(20), 2001
PMID: 11588192
NEMO/IKK gamma: linking NF-kappa B to human disease.
Courtois G, Smahi A, Israel A., Trends Mol Med 7(10), 2001
PMID: 11597506
Potential anticonvulsive properties of endogenous prostaglandins formed in mouse brain.
Forstermann U, Heldt R, Knappen F, Hertting G., Brain Res. 240(2), 1982
PMID: 6809223
Firefly luciferase gene: structure and expression in mammalian cells.
de Wet JR, Wood KV, DeLuca M, Helinski DR, Subramani S., Mol. Cell. Biol. 7(2), 1987
PMID: 3821727
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements.
Lee W, Mitchell P, Tjian R., Cell 49(6), 1987
PMID: 3034433
Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor.
Baeuerle PA, Baltimore D., Cell 53(2), 1988
PMID: 3129195
The NF-kappa B-binding site mediates phorbol ester-inducible transcription in nonlymphoid cells.
Nelsen B, Hellman L, Sen R., Mol. Cell. Biol. 8(8), 1988
PMID: 3145412
An automated method for calcium phosphate-mediated gene transfer.
Steiner C, Kaltschmidt C., Trends Genet. 5(5), 1989
PMID: 2756562
HIV enhancer activity perpetuated by NF-kappa B induction on infection of monocytes.
Bachelerie F, Alcami J, Arenzana-Seisdedos F, Virelizier JL., Nature 350(6320), 1991
PMID: 2023633
A simple method for organotypic cultures of nervous tissue.
Stoppini L, Buchs PA, Muller D., J. Neurosci. Methods 37(2), 1991
PMID: 1715499
The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B.
Schmitz ML, Baeuerle PA., EMBO J. 10(12), 1991
PMID: 1935902
Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation.
Kunsch C, Ruben SM, Rosen CA., Mol. Cell. Biol. 12(10), 1992
PMID: 1406630
Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids.
Yamagata K, Andreasson KI, Kaufmann WE, Barnes CA, Worley PF., Neuron 11(2), 1993
PMID: 8352945
Formation of layer-specific fiber projections to the hippocampus in vitro.
Frotscher M, Heimrich B., Proc. Natl. Acad. Sci. U.S.A. 90(21), 1993
PMID: 8234306
Brain synapses contain inducible forms of the transcription factor NF-kappa B.
Kaltschmidt C, Kaltschmidt B, Baeuerle PA., Mech. Dev. 43(2-3), 1993
PMID: 8297787
Constitutive NF-kappa B activity in neurons.
Kaltschmidt C, Kaltschmidt B, Neumann H, Wekerle H, Baeuerle PA., Mol. Cell. Biol. 14(6), 1994
PMID: 8196637
Nuclear factor-kappa B in rat brain: enhanced DNA-binding activity following convulsant-induced seizures.
Prasad AV, Pilcher WH, Joseph SA., Neurosci. Lett. 170(1), 1994
PMID: 8041493
Inhibition of NF-kappa B by sodium salicylate and aspirin.
Kopp E, Ghosh S., Science 265(5174), 1994
PMID: 8052854
Characterization of the genomic structure, chromosomal location and promoter of human prostaglandin H synthase-2 gene.
Tazawa R, Xu XM, Wu KK, Wang LH., Biochem. Biophys. Res. Commun. 203(1), 1994
PMID: 8074655
Characterization of inducible cyclooxygenase in rat brain.
Breder CD, Dewitt D, Kraig RP., J. Comp. Neurol. 355(2), 1995
PMID: 7608344
Selective recognition of the activated form of transcription factor NF-kappa B by a monoclonal antibody.
Kaltschmidt C, Kaltschmidt B, Henkel T, Stockinger H, Baeuerle PA., Biol. Chem. Hoppe-Seyler 376(1), 1995
PMID: 7612189
Stimulation of ionotropic glutamate receptors activates transcription factor NF-kappa B in primary neurons.
Kaltschmidt C, Kaltschmidt B, Baeuerle PA., Proc. Natl. Acad. Sci. U.S.A. 92(21), 1995
PMID: 7568184
Synaptic activation of NF-kappa B by glutamate in cerebellar granule neurons in vitro.
Guerrini L, Blasi F, Denis-Donini S., Proc. Natl. Acad. Sci. U.S.A. 92(20), 1995
PMID: 7568076
Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.
Barger SW, Horster D, Furukawa K, Goodman Y, Krieglstein J, Mattson MP., Proc. Natl. Acad. Sci. U.S.A. 92(20), 1995
PMID: 7568127
COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex.
Kaufmann WE, Worley PF, Pegg J, Bremer M, Isakson P., Proc. Natl. Acad. Sci. U.S.A. 93(6), 1996
PMID: 8637870
Spine loss in experimental epilepsy: quantitative light and electron microscopic analysis of intracellularly stained CA3 pyramidal cells in hippocampal slice cultures.
Drakew A, Muller M, Gahwiler BH, Thompson SM, Frotscher M., Neuroscience 70(1), 1996
PMID: 8848134
NF-kappaB activity in transgenic mice: developmental regulation and tissue specificity.
Schmidt-Ullrich R, Memet S, Lilienbaum A, Feuillard J, Raphael M, Israel A., Development 122(7), 1996
PMID: 8681793
The NF-kappa B and I kappa B proteins: new discoveries and insights.
Baldwin AS Jr., Annu. Rev. Immunol. 14(), 1996
PMID: 8717528
Gene expression of the transcription factor NF-kappa B in hippocampus: regulation by synaptic activity.
Meberg PJ, Kinney WR, Valcourt EG, Routtenberg A., Brain Res. Mol. Brain Res. 38(2), 1996
PMID: 8793106
Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappaB activation.
Grilli M, Pizzi M, Memo M, Spano P., Science 274(5291), 1996
PMID: 8910280
Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease.
Kaltschmidt B, Uherek M, Volk B, Baeuerle PA, Kaltschmidt C., Proc. Natl. Acad. Sci. U.S.A. 94(6), 1997
PMID: 9122249
NF-kappa B: a crucial transcription factor for glial and neuronal cell function.
O'Neill LA, Kaltschmidt C., Trends Neurosci. 20(6), 1997
PMID: 9185306
Glutamate-dependent activation of NF-kappaB during mouse cerebellum development.
Guerrini L, Molteni A, Wirth T, Kistler B, Blasi F., J. Neurosci. 17(16), 1997
PMID: 9236217
Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration.
Mattson MP, Goodman Y, Luo H, Fu W, Furukawa K., J. Neurosci. Res. 49(6), 1997
PMID: 9335256
Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-kappaB and stabilization of calcium homeostasis.
Guo Q, Robinson N, Mattson MP., J. Biol. Chem. 273(20), 1998
PMID: 9575187
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation.
Yamaoka S, Courtois G, Bessia C, Whiteside ST, Weil R, Agou F, Kirk HE, Kay RJ, Israel A., Cell 93(7), 1998
PMID: 9657155
Strong nuclear factor-kappaB-DNA binding parallels cyclooxygenase-2 gene transcription in aging and in sporadic Alzheimer's disease superior temporal lobe neocortex.
Lukiw WJ, Bazan NG., J. Neurosci. Res. 53(5), 1998
PMID: 9726429
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