Transcription factor NF-kB is activated in primary neurons by amyloid ß peptides and in neurons surrounding early plaques from patients with Alzheimer disease

Kaltschmidt, Barbara; Uherek, M.; Volk, B.; Baeuerle, P.A.; Kaltschmidt, Christian

Transcription factor NF-kB is activated in primary neurons by amyloid ß peptides and in neurons surrounding early plaques from patients with Alzheimer disease

Kaltschmidt B, Uherek M, Volk B, Baeuerle PA, Kaltschmidt C (1997)
Proc. Natl. Acad. Sci. USA 94(6): 2642-2647.

Zeitschriftenaufsatz | Veröffentlicht | Englisch

Download

Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!

DOI

https://doi.org/10.1073/pnas.94.6.2642

Autor*in

Kaltschmidt, Barbara^UniBi; Uherek, M.; Volk, B.; Baeuerle, P.A.; Kaltschmidt, Christian^UniBi

Einrichtung

Fakultät für Biologie > Zellbiologie der Tiere

Erscheinungsjahr

1997

Zeitschriftentitel

Proc. Natl. Acad. Sci. USA

Band

94

Ausgabe

6

Seite(n)

2642-2647

ISSN

0027-8424

Page URI

https://pub.uni-bielefeld.de/record/1865447

Zitieren

Kaltschmidt B, Uherek M, Volk B, Baeuerle PA, Kaltschmidt C. Transcription factor NF-kB is activated in primary neurons by amyloid ß peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc. Natl. Acad. Sci. USA. 1997;94(6):2642-2647.

Kaltschmidt, B., Uherek, M., Volk, B., Baeuerle, P. A., & Kaltschmidt, C. (1997). Transcription factor NF-kB is activated in primary neurons by amyloid ß peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc. Natl. Acad. Sci. USA, 94(6), 2642-2647. https://doi.org/10.1073/pnas.94.6.2642

Kaltschmidt, Barbara, Uherek, M., Volk, B., Baeuerle, P.A., and Kaltschmidt, Christian. 1997. “Transcription factor NF-kB is activated in primary neurons by amyloid ß peptides and in neurons surrounding early plaques from patients with Alzheimer disease”. Proc. Natl. Acad. Sci. USA 94 (6): 2642-2647.

Kaltschmidt, B., Uherek, M., Volk, B., Baeuerle, P. A., and Kaltschmidt, C. (1997). Transcription factor NF-kB is activated in primary neurons by amyloid ß peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc. Natl. Acad. Sci. USA 94, 2642-2647.

Kaltschmidt, B., et al., 1997. Transcription factor NF-kB is activated in primary neurons by amyloid ß peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc. Natl. Acad. Sci. USA, 94(6), p 2642-2647.

B. Kaltschmidt, et al., “Transcription factor NF-kB is activated in primary neurons by amyloid ß peptides and in neurons surrounding early plaques from patients with Alzheimer disease”, Proc. Natl. Acad. Sci. USA, vol. 94, 1997, pp. 2642-2647.

Kaltschmidt, B., Uherek, M., Volk, B., Baeuerle, P.A., Kaltschmidt, C.: Transcription factor NF-kB is activated in primary neurons by amyloid ß peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc. Natl. Acad. Sci. USA. 94, 2642-2647 (1997).

Kaltschmidt, Barbara, Uherek, M., Volk, B., Baeuerle, P.A., and Kaltschmidt, Christian. “Transcription factor NF-kB is activated in primary neurons by amyloid ß peptides and in neurons surrounding early plaques from patients with Alzheimer disease”. Proc. Natl. Acad. Sci. USA 94.6 (1997): 2642-2647.

328 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Association of adipocyte enhancer-binding protein 1 with Alzheimer's disease pathology in human hippocampi.
Shijo M, Honda H, Suzuki SO, Hamasaki H, Hokama M, Abolhassani N, Nakabeppu Y, Ninomiya T, Kitazono T, Iwaki T., Brain Pathol 28(1), 2018
PMID: 27997051

Angiotensin II Receptor Blockers Attenuate Lipopolysaccharide-Induced Memory Impairment by Modulation of NF-κB-Mediated BDNF/CREB Expression and Apoptosis in Spontaneously Hypertensive Rats.
Goel R, Bhat SA, Hanif K, Nath C, Shukla R., Mol Neurobiol 55(2), 2018
PMID: 28215000

Regulation of Survival Motor Neuron Protein by the Nuclear Factor-Kappa B Pathway in Mouse Spinal Cord Motoneurons.
Arumugam S, Mincheva-Tasheva S, Periyakaruppiah A, de la Fuente S, Soler RM, Garcera A., Mol Neurobiol 55(6), 2018
PMID: 28808928

Shared pathological pathways of Alzheimer's disease with specific comorbidities: current perspectives and interventions.
Nday CM, Eleftheriadou D, Jackson G., J Neurochem 144(4), 2018
PMID: 29164610

Oil Palm Phenolics Inhibit the In Vitro Aggregation of β-Amyloid Peptide into Oligomeric Complexes.
Weinberg RP, Koledova VV, Shin H, Park JH, Tan YA, Sinskey AJ, Sambanthamurthi R, Rha C., Int J Alzheimers Dis 2018(), 2018
PMID: 29666700

Palmitate-induced C/EBP homologous protein activation leads to NF-κB-mediated increase in BACE1 activity and amyloid beta genesis.
Marwarha G, Schommer J, Lund J, Schommer T, Ghribi O., J Neurochem 144(6), 2018
PMID: 29315574

An Inflammation-Centric View of Neurological Disease: Beyond the Neuron.
Skaper SD, Facci L, Zusso M, Giusti P., Front Cell Neurosci 12(), 2018
PMID: 29618972

Deciphering the Astrocyte Reaction in Alzheimer's Disease.
Perez-Nievas BG, Serrano-Pozo A., Front Aging Neurosci 10(), 2018
PMID: 29922147

Piperlongumine Improves Lipopolysaccharide-Induced Amyloidogenesis by Suppressing NF-KappaB Pathway.
Gu SM, Lee HP, Ham YW, Son DJ, Kim HY, Oh KW, Han SB, Yun J, Hong JT., Neuromolecular Med 20(3), 2018
PMID: 29802525

Isorhynchophylline alleviates learning and memory impairments induced by aluminum chloride in mice.
Li HQ, Ip SP, Zheng GQ, Xian YF, Lin ZX., Chin Med 13(), 2018
PMID: 29946349

S100B immunization triggers NFκB and complement activation in an autoimmune glaucoma model.
Reinehr S, Reinhard J, Gandej M, Gottschalk I, Stute G, Faissner A, Dick HB, Joachim SC., Sci Rep 8(1), 2018
PMID: 29959432

Astrocytic NF-κB brings the best and worst out of microglia.
Dokalis N, Prinz M., EMBO J 37(16), 2018
PMID: 30037825

Astroglia contribute to the pathogenesis of spinocerebellar ataxia Type 1 (SCA1) in a biphasic, stage-of-disease specific manner.
Kim JH, Lukowicz A, Qu W, Johnson A, Cvetanovic M., Glia 66(9), 2018
PMID: 30043530

Inflammation as a central mechanism in Alzheimer's disease.
Kinney JW, Bemiller SM, Murtishaw AS, Leisgang AM, Salazar AM, Lamb BT., Alzheimers Dement (N Y) 4(), 2018
PMID: 30406177

NF-κB p65 directs sex-specific neuroprotection in human neurons.
Ruiz-Perera LM, Schneider L, Windmöller BA, Müller J, Greiner JFW, Kaltschmidt C, Kaltschmidt B., Sci Rep 8(1), 2018
PMID: 30375448

Inhibition of miR-128 Abates Aβ-Mediated Cytotoxicity by Targeting PPAR-γ via NF-κB Inactivation in Primary Mouse Cortical Neurons and Neuro2a Cells.
Geng L, Zhang T, Liu W, Chen Y., Yonsei Med J 59(9), 2018
PMID: 30328325

miR-15b reduces amyloid-β accumulation in SH-SY5Y cell line through targetting NF-κB signaling and BACE1.
Li J, Wang H., Biosci Rep 38(6), 2018
PMID: 29961672

Poly(ADP-ribose)polymerase-1 hyperactivation in neurodegenerative diseases: The death knell tolls for neurons.
Narne P, Pandey V, Simhadri PK, Phanithi PB., Semin Cell Dev Biol 63(), 2017
PMID: 27867042

The DNA Damage Response in Neurons: Die by Apoptosis or Survive in a Senescence-Like State?
Fielder E, von Zglinicki T, Jurk D., J Alzheimers Dis 60(s1), 2017
PMID: 28436392

Serotonin transporter and receptor ligands with antidepressant activity as neuroprotective and proapoptotic agents.
Chilmonczyk Z, Bojarski AJ, Pilc A, Sylte I., Pharmacol Rep 69(3), 2017
PMID: 28324844

Metformin activation of AMPK suppresses AGE-induced inflammatory response in hNSCs.
Chung MM, Nicol CJ, Cheng YC, Lin KH, Chen YL, Pei D, Lin CH, Shih YN, Yen CH, Chen SJ, Huang RN, Chiang MC., Exp Cell Res 352(1), 2017
PMID: 28159472

Potential of GPCRs to modulate MAPK and mTOR pathways in Alzheimer's disease.
Franco R, Martínez-Pinilla E, Navarro G, Zamarbide M., Prog Neurobiol 149-150(), 2017
PMID: 28189739

Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer's Disease Brain.
Thangavel R, Kempuraj D, Zaheer S, Raikwar S, Ahmed ME, Selvakumar GP, Iyer SS, Zaheer A., Front Aging Neurosci 9(), 2017
PMID: 28572767

Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer's disease.
Nho K, Kim S, Horgusluoglu E, Risacher SL, Shen L, Kim D, Lee S, Foroud T, Shaw LM, Trojanowski JQ, Aisen PS, Petersen RC, Jack CR, Weiner MW, Green RC, Toga AW, Saykin AJ, Alzheimer’s Disease Neuroimaging Initiative (ADNI)., BMC Med Genomics 10(suppl 1), 2017
PMID: 28589856

Transcriptomics, NF-κB Pathway, and Their Potential Spaceflight-Related Health Consequences.
Zhang Y, Moreno-Villanueva M, Krieger S, Ramesh GT, Neelam S, Wu H., Int J Mol Sci 18(6), 2017
PMID: 28561779

Reactive Astrocytes: Production, Function, and Therapeutic Potential.
Liddelow SA, Barres BA., Immunity 46(6), 2017
PMID: 28636962

Ferulic acid and its water-soluble derivatives inhibit nitric oxide production and inducible nitric oxide synthase expression in rat primary astrocytes.
Kikugawa M, Ida T, Ihara H, Sakamoto T., Biosci Biotechnol Biochem 81(8), 2017
PMID: 28608752

miR-137 attenuates Aβ-induced neurotoxicity through inactivation of NF-κB pathway by targeting TNFAIP1 in Neuro2a cells.
He D, Tan J, Zhang J., Biochem Biophys Res Commun 490(3), 2017
PMID: 28655611

Brain region- and sex-specific alterations in mitochondrial function and NF-κB signaling in the TgCRND8 mouse model of Alzheimer's disease.
Djordjevic J, Thomson E, Chowdhury SR, Snow WM, Perez C, Wong TP, Fernyhough P, Albensi BC., Neuroscience 361(), 2017
PMID: 28802916

Loss of NLRX1 Exacerbates Neural Tissue Damage and NF-κB Signaling following Brain Injury.
Theus MH, Brickler T, Meza AL, Coutermarsh-Ott S, Hazy A, Gris D, Allen IC., J Immunol 199(10), 2017
PMID: 28993512

Network-Driven Proteogenomics Unveils an Aging-Related Imbalance in the Olfactory IκBα-NFκB p65 Complex Functionality in Tg2576 Alzheimer's Disease Mouse Model.
Palomino-Alonso M, Lachén-Montes M, González-Morales A, Ausín K, Pérez-Mediavilla A, Fernández-Irigoyen J, Santamaría E., Int J Mol Sci 18(11), 2017
PMID: 29077059

Epigenetic Regulatory Mechanisms Induced by Resveratrol.
Fernandes GFS, Silva GDB, Pavan AR, Chiba DE, Chin CM, Dos Santos JL., Nutrients 9(11), 2017
PMID: 29104258

Age-Dependent Alterations in the Interactions of NF-κB and N-myc with GLT-1/EAAT2 Promoter in the Pericontusional Cortex of Mice Subjected to Traumatic Brain Injury.
Gupta RK, Prasad S., Mol Neurobiol 53(5), 2016
PMID: 26081154

Signaling pathways regulating neuron-glia interaction and their implications in Alzheimer's disease.
Lian H, Zheng H., J Neurochem 136(3), 2016
PMID: 26546579

Non-Neuronal Cells Are Required to Mediate the Effects of Neuroinflammation: Results from a Neuron-Enriched Culture System.
Hui CW, Zhang Y, Herrup K., PLoS One 11(1), 2016
PMID: 26788729

Ginsenoside Rg1 exerts a protective effect against Aβ₂₅₋₃₅-induced toxicity in primary cultured rat cortical neurons through the NF-κB/NO pathway.
Wu J, Yang H, Zhao Q, Zhang X, Lou Y., Int J Mol Med 37(3), 2016
PMID: 26865401

PPARδ agonist GW0742 ameliorates Aβ1-42-induced hippocampal neurotoxicity in mice.
An YQ, Zhang CT, Du Y, Zhang M, Tang SS, Hu M, Long Y, Sun HB, Hong H., Metab Brain Dis 31(3), 2016
PMID: 26864581

Inhibition of the neuronal NFκB pathway attenuates bortezomib-induced neuropathy in a mouse model.
Alé A, Bruna J, Calls A, Karamita M, Haralambous S, Probert L, Navarro X, Udina E., Neurotoxicology 55(), 2016
PMID: 27211850

c-Rel is Required for the Induction of pTregs in the Eye but Not in the Gut Mucosa.
Wang T, Shi W, Fan T, Wan X, Chen YH, Ruan Q., Immunol Invest 45(8), 2016
PMID: 27224262

Statins Inhibit Fibrillary β-Amyloid Induced Inflammation in a Model of the Human Blood Brain Barrier.
Griffin JM, Kho D, Graham ES, Nicholson LF, O'Carroll SJ., PLoS One 11(6), 2016
PMID: 27309956

Protective Role of Corilagin on Aβ25-35-Induced Neurotoxicity: Suppression of NF-κB Signaling Pathway.
Youn K, Lee S, Jeong WS, Ho CT, Jun M., J Med Food 19(10), 2016
PMID: 27654707

Integrating network, sequence and functional features using machine learning approaches towards identification of novel Alzheimer genes.
Jamal S, Goyal S, Shanker A, Grover A., BMC Genomics 17(1), 2016
PMID: 27756223

Neuronal Gene Targets of NF-κB and Their Dysregulation in Alzheimer's Disease.
Snow WM, Albensi BC., Front Mol Neurosci 9(), 2016
PMID: 27881951

LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways.
Yang L, Liu CC, Zheng H, Kanekiyo T, Atagi Y, Jia L, Wang D, N'songo A, Can D, Xu H, Chen XF, Bu G., J Neuroinflammation 13(1), 2016
PMID: 27931217

Concurrent Treatment with Taxifolin and Cilostazol on the Lowering of β-Amyloid Accumulation and Neurotoxicity via the Suppression of P-JAK2/P-STAT3/NF-κB/BACE1 Signaling Pathways.
Park SY, Kim HY, Park HJ, Shin HK, Hong KW, Kim CD., PLoS One 11(12), 2016
PMID: 27977755

Valproic acid alleviates memory deficits and attenuates amyloid-β deposition in transgenic mouse model of Alzheimer's disease.
Xuan AG, Pan XB, Wei P, Ji WD, Zhang WJ, Liu JH, Hong LP, Chen WL, Long DH., Mol Neurobiol 51(1), 2015
PMID: 24854198

Alzheimer's disease and type 2 diabetes via chronic inflammatory mechanisms.
Mushtaq G, Khan JA, Kumosani TA, Kamal MA., Saudi J Biol Sci 22(1), 2015
PMID: 25561876

Whole-food diet worsened cognitive dysfunction in an Alzheimer's disease mouse model.
Parrott MD, Winocur G, Bazinet RP, Ma DW, Greenwood CE., Neurobiol Aging 36(1), 2015
PMID: 25212462

Alcohol exposure after mild focal traumatic brain injury impairs neurological recovery and exacerbates localized neuroinflammation.
Teng SX, Katz PS, Maxi JK, Mayeux JP, Gilpin NW, Molina PE., Brain Behav Immun 45(), 2015
PMID: 25489880

NFκB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease.
Lian H, Yang L, Cole A, Sun L, Chiang AC, Fowler SW, Shim DJ, Rodriguez-Rivera J, Taglialatela G, Jankowsky JL, Lu HC, Zheng H., Neuron 85(1), 2015
PMID: 25533482

Mitochondrial lysates induce inflammation and Alzheimer's disease-relevant changes in microglial and neuronal cells.
Wilkins HM, Carl SM, Weber SG, Ramanujan SA, Festoff BW, Linseman DA, Swerdlow RH., J Alzheimers Dis 45(1), 2015
PMID: 25537010

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis.
Srinivasan M, Lahiri DK., Expert Opin Ther Targets 19(4), 2015
PMID: 25652642

Selective PCAF inhibitor ameliorates cognitive and behavioral deficits by suppressing NF-κB-mediated neuroinflammation induced by Aβ in a model of Alzheimer's disease.
Park SY, Kim MJ, Kim YJ, Lee YH, Bae D, Kim S, Na Y, Yoon HG., Int J Mol Med 35(4), 2015
PMID: 25672970

PARP-1 involvement in neurodegeneration: A focus on Alzheimer's and Parkinson's diseases.
Martire S, Mosca L, d'Erme M., Mech Ageing Dev 146-148(), 2015
PMID: 25881554

Lycopene abrogates Aβ(1-42)-mediated neuroinflammatory cascade in an experimental model of Alzheimer's disease.
Sachdeva AK, Chopra K., J Nutr Biochem 26(7), 2015
PMID: 25869595

NF-κB in Innate Neuroprotection and Age-Related Neurodegenerative Diseases.
Lanzillotta A, Porrini V, Bellucci A, Benarese M, Branca C, Parrella E, Spano PF, Pizzi M., Front Neurol 6(), 2015
PMID: 26042083

Paradoxical role of PKA inhibitor on amyloidβ-induced memory deficit.
Amini E, Nassireslami E, Payandemehr B, Khodagholi F, Foolad F, Khalaj S, Hamedani MP, Azimi L, Sharifzadeh M., Physiol Behav 149(), 2015
PMID: 26037462

Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.
Panmanee J, Nopparat C, Chavanich N, Shukla M, Mukda S, Song W, Vincent B, Govitrapong P., J Pineal Res 59(3), 2015
PMID: 26123100

Elusive roles for reactive astrocytes in neurodegenerative diseases.
Ben Haim L, Carrillo-de Sauvage MA, Ceyzériat K, Escartin C., Front Cell Neurosci 9(), 2015
PMID: 26283915

Dysregulation of the NF-κB pathway as a potential inducer of bipolar disorder.
Elhaik E, Zandi P., J Psychiatr Res 70(), 2015
PMID: 26424419

Magnesium Lithospermate B Protects Neurons Against Amyloid β (1-42)-Induced Neurotoxicity Through the NF-κB Pathway.
Jiang F, Mao Y, Liu H, Xu P, Zhang L, Qian X, Sun X., Neurochem Res 40(9), 2015
PMID: 26285901

Beyond the 5-HT3 receptors: A role for α7nACh receptors in neuroprotective aspects of tropisetron.
Khalifeh S, Fakhfouri G, Mehr SE, Mousavizadeh K, Dehpour AR, Khodagholi F, Kazmi S, Rahimian R., Hum Exp Toxicol 34(9), 2015
PMID: 26286524

Lipopolysaccharide from Rhodobacter sphaeroides Attenuates Microglia-Mediated Inflammation and Phagocytosis and Directs Regulatory T Cell Response.
Gaikwad S, Agrawal-Rajput R., Int J Inflam 2015(), 2015
PMID: 26457222

Suppression of MAPK attenuates neuronal cell death induced by activated glia-conditioned medium in alpha-synuclein overexpressing SH-SY5Y cells.
Yshii LM, Denadai-Souza A, Vasconcelos AR, Avellar MC, Scavone C., J Neuroinflammation 12(), 2015
PMID: 26502720

NF-KappaB in Long-Term Memory and Structural Plasticity in the Adult Mammalian Brain.
Kaltschmidt B, Kaltschmidt C., Front Mol Neurosci 8(), 2015
PMID: 26635522

Innate Immune Response in Brain, NF-Kappa B Signaling and Cystatins.
Kopitar-Jerala N., Front Mol Neurosci 8(), 2015
PMID: 26696821

NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review.
Shih RH, Wang CY, Yang CM., Front Mol Neurosci 8(), 2015
PMID: 26733801

Protein damage, repair and proteolysis.
Chondrogianni N, Petropoulos I, Grimm S, Georgila K, Catalgol B, Friguet B, Grune T, Gonos ES., Mol Aspects Med 35(), 2014
PMID: 23107776

Involvement of cysteinyl leukotriene receptor 1 in Aβ1-42-induced neurotoxicity in vitro and in vivo.
Tang SS, Hong H, Chen L, Mei ZL, Ji MJ, Xiang GQ, Li N, Ji H., Neurobiol Aging 35(3), 2014
PMID: 24269024

SET translocation is associated with increase in caspase cleaved amyloid precursor protein in CA1 of Alzheimer and Down syndrome patients.
Facchinetti P, Dorard E, Contremoulins V, Gaillard MC, Déglon N, Sazdovitch V, Guihenneuc-Jouyaux C, Brouillet E, Duyckaerts C, Allinquant B., Neurobiol Aging 35(5), 2014
PMID: 24262202

Nicotinamide treatment reduces the levels of oxidative stress, apoptosis, and PARP-1 activity in Aβ(1-42)-induced rat model of Alzheimer's disease.
Turunc Bayrakdar E, Uyanikgil Y, Kanit L, Koylu E, Yalcin A., Free Radic Res 48(2), 2014
PMID: 24151909

Complex regulation of acute and chronic neuroinflammatory responses in mouse models deficient for nuclear factor kappa B p50 subunit.
Rolova T, Puli L, Magga J, Dhungana H, Kanninen K, Wojciehowski S, Salminen A, Tanila H, Koistinaho J, Malm T., Neurobiol Dis 64(), 2014
PMID: 24345324

Optical and SPION-enhanced MR imaging shows that trans-stilbene inhibitors of NF-κB concomitantly lower Alzheimer's disease plaque formation and microglial activation in AβPP/PS-1 transgenic mouse brain.
Solberg NO, Chamberlin R, Vigil JR, Deck LM, Heidrich JE, Brown DC, Brady CI, Vander Jagt TA, Garwood M, Bisoffi M, Severns V, Vander Jagt DL, Sillerud LO., J Alzheimers Dis 40(1), 2014
PMID: 24413613

HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation.
Träger U, Andre R, Lahiri N, Magnusson-Lind A, Weiss A, Grueninger S, McKinnon C, Sirinathsinghji E, Kahlon S, Pfister EL, Moser R, Hummerich H, Antoniou M, Bates GP, Luthi-Carter R, Lowdell MW, Björkqvist M, Ostroff GR, Aronin N, Tabrizi SJ., Brain 137(pt 3), 2014
PMID: 24459107

MLK3-MKK3/6-P38MAPK cascades following N-methyl-D-aspartate receptor activation contributes to amyloid-β peptide-induced apoptosis in SH-SY5Y cells.
Zhou F, Xu Y, Hou XY., J Neurosci Res 92(6), 2014
PMID: 24482239

Interaction of transactive response DNA binding protein 43 with nuclear factor κB in mild cognitive impairment with episodic memory deficits.
Ohta Y, Tremblay C, Schneider JA, Bennett DA, Calon F, Julien JP., Acta Neuropathol Commun 2(), 2014
PMID: 24690380

Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway.
Marwarha G, Raza S, Meiers C, Ghribi O., Biochim Biophys Acta 1842(9), 2014
PMID: 24874077

Interleukin-1 signaling pathway as a therapeutic target in transthyretin amyloidosis.
Gonçalves NP, Vieira P, Saraiva MJ., Amyloid 21(3), 2014
PMID: 24918964

Parallels between major depressive disorder and Alzheimer's disease: role of oxidative stress and genetic vulnerability.
Rodrigues R, Petersen RB, Perry G., Cell Mol Neurobiol 34(7), 2014
PMID: 24927694

Intromitochondrial IκB/NF-κB signaling pathway is involved in amyloid β peptide-induced mitochondrial dysfunction.
Shi C, Zhu X, Wang J, Long D., J Bioenerg Biomembr 46(5), 2014
PMID: 25052843

Oridonin attenuates Aβ1-42-induced neuroinflammation and inhibits NF-κB pathway.
Wang S, Yang H, Yu L, Jin J, Qian L, Zhao H, Xu Y, Zhu X., PLoS One 9(8), 2014
PMID: 25121593

Protection of streptozotocin induced insulin receptor dysfunction, neuroinflammation and amyloidogenesis in astrocytes by insulin.
Rajasekar N, Dwivedi S, Nath C, Hanif K, Shukla R., Neuropharmacology 86(), 2014
PMID: 25158313

IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology.
Liu Y, Liu X, Hao W, Decker Y, Schomburg R, Fülöp L, Pasparakis M, Menger MD, Fassbender K., J Neurosci 34(39), 2014
PMID: 25253847

Negative regulation of NF-κB activity by brain-specific TRIpartite Motif protein 9.
Shi M, Cho H, Inn KS, Yang A, Zhao Z, Liang Q, Versteeg GA, Amini-Bavil-Olyaee S, Wong LY, Zlokovic BV, Park HS, García-Sastre A, Jung JU., Nat Commun 5(), 2014
PMID: 25190485

Protective role of luteolin against cognitive dysfunction induced by chronic cerebral hypoperfusion in rats.
Fu X, Zhang J, Guo L, Xu Y, Sun L, Wang S, Feng Y, Gou L, Zhang L, Liu Y., Pharmacol Biochem Behav 126(), 2014
PMID: 25220684

Quetiapine attenuates glial activation and proinflammatory cytokines in APP/PS1 transgenic mice via inhibition of nuclear factor-κB pathway.
Zhu S, Shi R, Li V, Wang J, Zhang R, Tempier A, He J, Kong J, Wang JF, Li XM., Int J Neuropsychopharmacol 18(3), 2014
PMID: 25618401

NF-κB signaling pathways: role in nervous system physiology and pathology.
Mincheva-Tasheva S, Soler RM., Neuroscientist 19(2), 2013
PMID: 22785105

Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony.
Medeiros R, LaFerla FM., Exp Neurol 239(), 2013
PMID: 23063604

Diammonium glycyrrhizinate attenuates Aβ(1-42) -induced neuroinflammation and regulates MAPK and NF-κB pathways in vitro and in vivo.
Zhao H, Wang SL, Qian L, Jin JL, Li H, Xu Y, Zhu XL., CNS Neurosci Ther 19(2), 2013
PMID: 23279783

Mechanisms of islet amyloidosis toxicity in type 2 diabetes.
Abedini A, Schmidt AM., FEBS Lett 587(8), 2013
PMID: 23337872

MicroRNA-195 protects against dementia induced by chronic brain hypoperfusion via its anti-amyloidogenic effect in rats.
Ai J, Sun LH, Che H, Zhang R, Zhang TZ, Wu WC, Su XL, Chen X, Yang G, Li K, Wang N, Ban T, Bao YN, Guo F, Niu HF, Zhu YL, Zhu XY, Zhao SG, Yang BF., J Neurosci 33(9), 2013
PMID: 23447608

Peripheral inflammation in neurodegeneration.
Träger U, Tabrizi SJ., J Mol Med (Berl) 91(6), 2013
PMID: 23546523

Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment.
Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, Green RC, Jack CR, Weiner MW, Baldwin CT, Lunetta K, Farrer LA, Multi-Institutional Research on Alzheimer Genetic Epidemiology (MIRAGE) Study, Furney SJ, Lovestone S, Simmons A, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, AddNeuroMed Consortium, McDonald BC, Farlow MR, Ghetti B, Indiana Memory and Aging Study, Huentelman MJ, Saykin AJ, Alzheimer's Disease Neuroimaging Initiative (ADNI)., Mol Psychiatry 18(7), 2013
PMID: 23608917

Trientine reduces BACE1 activity and mitigates amyloidosis via the AGE/RAGE/NF-κB pathway in a transgenic mouse model of Alzheimer's disease.
Wang CY, Xie JW, Xu Y, Wang T, Cai JH, Wang X, Zhao BL, An L, Wang ZY., Antioxid Redox Signal 19(17), 2013
PMID: 23541064

Selective inhibition of PCAF suppresses microglial-mediated β-amyloid neurotoxicity.
Park SY, Lee YH, Seong AR, Lee J, Jun W, Yoon HG., Int J Mol Med 32(2), 2013
PMID: 23740527

Hydrogen sulfide protects against amyloid beta-peptide induced neuronal injury via attenuating inflammatory responses in a rat model.
Fan H, Guo Y, Liang X, Yuan Y, Qi X, Wang M, Ma J, Zhou H., J Biomed Res 27(4), 2013
PMID: 23885269

Gemfibrozil pretreatment proved protection against acute restraint stress-induced changes in the male rats' hippocampus.
Khalaj L, Nejad SC, Mohammadi M, Zadeh SS, Pour MH, Ahmadiani A, Khodagholi F, Ashabi G, Alamdary SZ, Samami E., Brain Res 1527(), 2013
PMID: 23850768

Gadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells.
Marwarha G, Raza S, Prasanthi JR, Ghribi O., PLoS One 8(8), 2013
PMID: 23951005

Tropisetron attenuates amyloid-beta-induced inflammatory and apoptotic responses in rats.
Rahimian R, Fakhfouri G, Ejtemaei Mehr S, Ghia JE, Genazzani AA, Payandemehr B, Dehpour AR, Mousavizadeh K, Lim D., Eur J Clin Invest 43(10), 2013
PMID: 23937291

Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.
Chen CH, Zhou W, Liu S, Deng Y, Cai F, Tone M, Tone Y, Tong Y, Song W., Int J Neuropsychopharmacol 15(1), 2012
PMID: 21329555

Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease.
Swerdlow RH., Antioxid Redox Signal 16(12), 2012
PMID: 21902597

Salubrinal attenuates β-amyloid-induced neuronal death and microglial activation by inhibition of the NF-κB pathway.
Huang X, Chen Y, Zhang H, Ma Q, Zhang YW, Xu H., Neurobiol Aging 33(5), 2012
PMID: 22056200

Regulation of β-site APP-cleaving enzyme 1 gene expression and its role in Alzheimer's disease.
Sun X, Bromley-Brits K, Song W., J Neurochem 120 Suppl 1(), 2012
PMID: 22122349

Hsp70.1 and related lysosomal factors for necrotic neuronal death.
Yamashima T., J Neurochem 120(4), 2012
PMID: 22118687

Why are hippocampal CA1 neurons vulnerable but motor cortex neurons resistant to transient ischemia?
Zhu H, Yoshimoto T, Imajo-Ohmi S, Dazortsava M, Mathivanan A, Yamashima T., J Neurochem 120(4), 2012
PMID: 22017466

Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology.
Ferretti MT, Allard S, Partridge V, Ducatenzeiler A, Cuello AC., J Neuroinflammation 9(), 2012
PMID: 22472085

Neuronal NF-κB ablation does not influence neuro-axonal degeneration in experimental autoimmune demyelination.
Lee DH, Kubera K, Rosenthal B, Kaltschmidt B, Kaltschmidt C, Gold R, Linker RA., J Neuroimmunol 246(1-2), 2012
PMID: 22475633

WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway.
Fakhfouri G, Ahmadiani A, Rahimian R, Grolla AA, Moradi F, Haeri A., Neuropharmacology 63(4), 2012
PMID: 22634229

Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations.
Chami L, Buggia-Prévot V, Duplan E, Del Prete D, Chami M, Peyron JF, Checler F., J Biol Chem 287(29), 2012
PMID: 22654105

Hydrogen sulfide attenuates spatial memory impairment and hippocampal neuroinflammation in β-amyloid rat model of Alzheimer's disease.
Xuan A, Long D, Li J, Ji W, Zhang M, Hong L, Liu J., J Neuroinflammation 9(), 2012
PMID: 22898621

Late-onset Parkinsonism in NFκB/c-Rel-deficient mice.
Baiguera C, Alghisi M, Pinna A, Bellucci A, De Luca MA, Frau L, Morelli M, Ingrassia R, Benarese M, Porrini V, Pellitteri M, Bertini G, Fabene PF, Sigala S, Spillantini MG, Liou HC, Spano PF, Pizzi M., Brain 135(pt 9), 2012
PMID: 22915735

BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer's disease.
Chami L, Checler F., Mol Neurodegener 7(), 2012
PMID: 23039869

Transcriptional and post-transcriptional regulation of β-secretase.
Tamagno E, Guglielmotto M, Monteleone D, Vercelli A, Tabaton M., IUBMB Life 64(12), 2012
PMID: 23180460

Adiponectin is protective against oxidative stress induced cytotoxicity in amyloid-beta neurotoxicity.
Chan KH, Lam KS, Cheng OY, Kwan JS, Ho PW, Cheng KK, Chung SK, Ho JW, Guo VY, Xu A., PLoS One 7(12), 2012
PMID: 23300647

Effects of Fructus mume Extract on MAPK and NF-κB Signaling and the Resultant Improvement in the Cognitive Deficits Induced by Chronic Cerebral Hypoperfusion.
Jeon WK, Ma J, Choi BR, Han SH, Jin Q, Hwang BY, Han JS., Evid Based Complement Alternat Med 2012(), 2012
PMID: 23346201

APOE dependent-association of PPAR-γ genetic variants with Alzheimer's disease risk.
Combarros O, Rodríguez-Rodríguez E, Mateo I, Vázquez-Higuera JL, Infante J, Berciano J, Sánchez-Juan P., Neurobiol Aging 32(3), 2011
PMID: 19660836

Transcriptional control of maladaptive and protective responses in alcoholics: a role of the NF-κB system.
Yakovleva T, Bazov I, Watanabe H, Hauser KF, Bakalkin G., Brain Behav Immun 25 Suppl 1(), 2011
PMID: 21195164

Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease.
Nijholt DA, de Graaf TR, van Haastert ES, Oliveira AO, Berkers CR, Zwart R, Ovaa H, Baas F, Hoozemans JJ, Scheper W., Cell Death Differ 18(6), 2011
PMID: 21252911

Tetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting NF-κB activation in a rat model of Alzheimer's disease induced by amyloid-β(1-42).
He FQ, Qiu BY, Zhang XH, Li TK, Xie Q, Cui DJ, Huang XL, Gan HT., Brain Res 1384(), 2011
PMID: 21300035

Tetrandrine suppresses amyloid-β-induced inflammatory cytokines by inhibiting NF-κB pathway in murine BV2 microglial cells.
He FQ, Qiu BY, Li TK, Xie Q, Cui DJ, Huang XL, Gan HT., Int Immunopharmacol 11(9), 2011
PMID: 21496499

The miRNA pathway in neurological and skeletal muscle disease: implications for pathogenesis and therapy.
Sibley CR, Wood MJ., J Mol Med (Berl) 89(11), 2011
PMID: 21751030

Development of spontaneous neuropathy in NF-κBp50-deficient mice by calcineurin-signal involving impaired NF-κB activation.
Nakamura-Yanagidaira T, Takahashi Y, Sano K, Murata T, Hayashi T., Mol Vis 17(), 2011
PMID: 21850191

Characterisation of amyloid-induced inflammatory responses in the rat retina.
Howlett DR, Bate ST, Collier S, Lawman A, Chapman T, Ashmeade T, Marshall I, Anderson PJ, Philpott KL, Richardson JC, Hille CJ., Exp Brain Res 214(2), 2011
PMID: 21850448

Formation and signaling actions of electrophilic lipids.
Schopfer FJ, Cipollina C, Freeman BA., Chem Rev 111(10), 2011
PMID: 21928855

Gallic acid, a histone acetyltransferase inhibitor, suppresses β-amyloid neurotoxicity by inhibiting microglial-mediated neuroinflammation.
Kim MJ, Seong AR, Yoo JY, Jin CH, Lee YH, Kim YJ, Lee J, Jun WJ, Yoon HG., Mol Nutr Food Res 55(12), 2011
PMID: 22038937

NF-kappaB signaling in neurite growth and neuronal survival.
Teng FY, Tang BL., Rev Neurosci 21(4), 2010
PMID: 21086762

The consequences of mitochondrial amyloid beta-peptide in Alzheimer's disease.
Muirhead KE, Borger E, Aitken L, Conway SJ, Gunn-Moore FJ., Biochem J 426(3), 2010
PMID: 20175748

TAp63 is a transcriptional target of NF-kappaB.
Wu J, Bergholz J, Lu J, Sonenshein GE, Xiao ZX., J Cell Biochem 109(4), 2010
PMID: 20052674

Transcriptional regulation of UCP4 by NF-kappaB and its role in mediating protection against MPP+ toxicity.
Ho JW, Ho PW, Zhang WY, Liu HF, Kwok KH, Yiu DC, Chan KH, Kung MH, Ramsden DB, Ho SL., Free Radic Biol Med 49(2), 2010
PMID: 20385226

Neuroprotective herbs and foods from different traditional medicines and diets.
Iriti M, Vitalini S, Fico G, Faoro F., Molecules 15(5), 2010
PMID: 20657497

Control of transferrin expression by β-amyloid through the CP2 transcription factor.
Jang SM, Kim JW, Kim CH, An JH, Kang EJ, Kim CG, Kim HJ, Choi KH., FEBS J 277(19), 2010
PMID: 20796026

The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells.
Dasari B, Prasanthi JR, Marwarha G, Singh BB, Ghribi O., BMC Ophthalmol 10(), 2010
PMID: 20836858

Quercetin activates AMP-activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol-induced neurotoxicity.
Lu J, Wu DM, Zheng YL, Hu B, Zhang ZF, Shan Q, Zheng ZH, Liu CM, Wang YJ., J Pathol 222(2), 2010
PMID: 20690163

Changes in TNFα, NFκB and MnSOD protein in the vestibular nuclei after unilateral vestibular deafferentation.
Liberge M, Manrique C, Bernard-Demanze L, Lacour M., J Neuroinflammation 7(), 2010
PMID: 21143912

Mechanisms of neurodegeneration and regeneration in alcoholism.
Crews FT, Nixon K., Alcohol Alcohol 44(2), 2009
PMID: 18940959

Post-ischemic brain damage: NF-kappaB dimer heterogeneity as a molecular determinant of neuron vulnerability.
Pizzi M, Sarnico I, Lanzillotta A, Battistin L, Spano P., FEBS J 276(1), 2009
PMID: 19087197

Gene-gene interaction between CARD8 and interleukin-6 reduces Alzheimer's disease risk.
Fontalba A, Gutiérrez O, Llorca J, Mateo I, Vázquez-Higuera JL, Berciano J, Fernández-Luna JL, Combarros O., J Neurol 256(7), 2009
PMID: 19252766

Suppression of nuclear factor kappa B ameliorates astrogliosis but not amyloid burden in APPswe/PS1dE9 mice.
Zhang X, Luhrs KJ, Ryff KA, Malik WT, Driscoll MJ, Culver B., Neuroscience 161(1), 2009
PMID: 19286451

Tetanus toxin H(C) fragment reduces neuronal MPP+ toxicity.
Chaïb-Oukadour I, Gil C, Rodríguez-Alvarez J, Ortega A, Aguilera J., Mol Cell Neurosci 41(3), 2009
PMID: 19344769

Sorafenib inhibits nuclear factor kappa B, decreases inducible nitric oxide synthase and cyclooxygenase-2 expression, and restores working memory in APPswe mice.
Echeverria V, Burgess S, Gamble-George J, Zeitlin R, Lin X, Cao C, Arendash GW., Neuroscience 162(4), 2009
PMID: 19447162

Tripchlorolide protects neuronal cells from microglia-mediated beta-amyloid neurotoxicity through inhibiting NF-kappaB and JNK signaling.
Pan XD, Chen XC, Zhu YG, Chen LM, Zhang J, Huang TW, Ye QY, Huang HP., Glia 57(11), 2009
PMID: 19170180

DNA methylation of Alzheimer disease and tauopathy-related genes in postmortem brain.
Barrachina M, Ferrer I., J Neuropathol Exp Neurol 68(8), 2009
PMID: 19606065

NF-kappaB in the nervous system.
Kaltschmidt B, Kaltschmidt C., Cold Spring Harb Perspect Biol 1(3), 2009
PMID: 20066105

Neuroprotective effects of the new diterpene, CBNU06 against beta-amyloid-induced toxicity through the inhibition of NF-kappaB signaling pathway in PC12 cells.
Kim HS, Lim JY, Sul D, Hwang BY, Won TJ, Hwang KW, Park SY., Eur J Pharmacol 622(1-3), 2009
PMID: 19765580

Ectodomain shedding of the receptor for advanced glycation end products: a novel therapeutic target for Alzheimer's disease.
Zhang L, Postina R, Wang Y., Cell Mol Life Sci 66(24), 2009
PMID: 19672558

Combination of linkage mapping and microarray-expression analysis identifies NF-kappaB signaling defect as a cause of autosomal-recessive mental retardation.
Philippe O, Rio M, Carioux A, Plaza JM, Guigue P, Molinari F, Boddaert N, Bole-Feysot C, Nitschke P, Smahi A, Munnich A, Colleaux L., Am J Hum Genet 85(6), 2009
PMID: 20004764

Converging concepts: adaptive response, preconditioning, and the Yerkes-Dodson Law are manifestations of hormesis.
Calabrese EJ., Ageing Res Rev 7(1), 2008
PMID: 17768095

Effect on memory of acute administration of naturally secreted fibrils and synthetic amyloid-beta peptides in an invertebrate model.
Feld M, Galli C, Piccini A, Romano A., Neurobiol Learn Mem 89(4), 2008
PMID: 17920304

Anti-inflammatory interventions of NF-kappaB signaling: potential applications and risks.
Uwe S., Biochem Pharmacol 75(8), 2008
PMID: 18070616

Accumulation of phosphorylated I kappaB alpha and activated IKK in nodes of Ranvier.
Politi C, Del Turco D, Sie JM, Golinski PA, Tegeder I, Deller T, Schultz C., Neuropathol Appl Neurobiol 34(3), 2008
PMID: 17986183

Pharmacological enhancement of neuronal survival.
Calabrese EJ., Crit Rev Toxicol 38(4), 2008
PMID: 18432420

NF-kappaB signaling pathway and its therapeutic implications in human diseases.
Sarkar FH, Li Y, Wang Z, Kong D., Int Rev Immunol 27(5), 2008
PMID: 18853341

Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes.
Sarnico I, Boroni F, Benarese M, Alghisi M, Valerio A, Battistin L, Spano P, Pizzi M., J Neural Transm (Vienna) 115(5), 2008
PMID: 18197358

Amyloid beta-peptide activates nuclear factor-kappaB through an N-methyl-D-aspartate signaling pathway in cultured cerebellar cells.
Kawamoto EM, Lepsch LB, Boaventura MF, Munhoz CD, Lima LS, Yshii LM, Avellar MC, Curi R, Mattson MP, Scavone C., J Neurosci Res 86(4), 2008
PMID: 17969100

Curcumin protects dopaminergic neuron against LPS induced neurotoxicity in primary rat neuron/glia culture.
Yang S, Zhang D, Yang Z, Hu X, Qian S, Liu J, Wilson B, Block M, Hong JS., Neurochem Res 33(10), 2008
PMID: 18368483

Induction of heat shock proteins and the proteasome system by casein-N epsilon-(carboxymethyl)lysine and N epsilon-(carboxymethyl)lysine in Caco-2 cells.
Schmid K, Haslbeck M, Buchner J, Somoza V., Ann N Y Acad Sci 1126(), 2008
PMID: 18448826

Flavanols, mild cognitive impairment, and Alzheimer's dementia.
Patel AK, Rogers JT, Huang X., Int J Clin Exp Med 1(2), 2008
PMID: 19079672

p75(NTR) activation of NF-kappaB is involved in PrP106-126-induced apoptosis in mouse neuroblastoma cells.
Bai Y, Li Q, Yang J, Zhou X, Yin X, Zhao D., Neurosci Res 62(1), 2008
PMID: 18602709

Activation of nuclear factor-kappaB during retinal degeneration in rd mice.
Zeng HY, Tso MO, Lai S, Lai H., Mol Vis 14(), 2008
PMID: 18552981

Dynein light chain LC8 negatively regulates NF-kappaB through the redox-dependent interaction with IkappaBalpha.
Jung Y, Kim H, Min SH, Rhee SG, Jeong W., J Biol Chem 283(35), 2008
PMID: 18579519

Raf inhibition protects cortical cells against beta-amyloid toxicity.
Echeverria V, Burgess S, Gamble-George J, Arendash GW, Citron BA., Neurosci Lett 444(1), 2008
PMID: 18706973

The role and regulation of the nuclear factor kappa B signalling pathway in human labour.
Lappas M, Rice GE., Placenta 28(5-6), 2007
PMID: 16843526

Inhibition of Abeta production by NF-kappaB inhibitors.
Paris D, Patel N, Quadros A, Linan M, Bakshi P, Ait-Ghezala G, Mullan M., Neurosci Lett 415(1), 2007
PMID: 17223266

Anti-apoptotic signaling and failure of apoptosis in the ischemic rat hippocampus.
Müller GJ, Lassmann H, Johansen FF., Neurobiol Dis 25(3), 2007
PMID: 17207631

NF-kappa B as a therapeutic target in neurodegenerative diseases.
Camandola S, Mattson MP., Expert Opin Ther Targets 11(2), 2007
PMID: 17227229

CD40 promotion of amyloid beta production occurs via the NF-kappaB pathway.
Ait-Ghezala G, Volmar CH, Frieling J, Paris D, Tweed M, Bakshi P, Mullan M., Eur J Neurosci 25(6), 2007
PMID: 17432959

Nuclear factor kappa-B p50 and p65 subunits expression in dementia with Lewy bodies.
Saldaña M, Mullol J, Aguilar E, Bonastre M, Marin C., Neuropathol Appl Neurobiol 33(3), 2007
PMID: 17442064

Hydrogen peroxide induces the death of astrocytes through the down-regulation of the constitutive nuclear factor-kappaB activity.
Choi JJ, Choi J, Kang CD, Chen X, Wu CF, Ko KH, Kim WK., Free Radic Res 41(5), 2007
PMID: 17454138

Over-expression of amyloid precursor protein in HEK cells alters p53 conformational state and protects against doxorubicin.
Uberti D, Cenini G, Olivari L, Ferrari-Toninelli G, Porrello E, Cecchi C, Pensalfini A, Liguri G, Govoni S, Racchi M, Maurizio M., J Neurochem 103(1), 2007
PMID: 17608641

Chronic treatment of rats with sodium valproate downregulates frontal cortex NF-kappaB DNA binding activity and COX-2 mRNA.
Rao JS, Bazinet RP, Rapoport SI, Lee HJ., Bipolar Disord 9(5), 2007
PMID: 17680922

Assessment of the astrogliotic responses of three human astrocytoma cell lines to ethanol, trimethyltin chloride and acrylamide.
Holden LJ, Coleman MD., Toxicology 241(1-2), 2007
PMID: 17875352

Nuclear factor-kappa B regulates seizure threshold and gene transcription following convulsant stimulation.
Lubin FD, Ren Y, Xu X, Anderson AE., J Neurochem 103(4), 2007
PMID: 17727632

Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system.
Okvist A, Johansson S, Kuzmin A, Bazov I, Merino-Martinez R, Ponomarev I, Mayfield RD, Harris RA, Sheedy D, Garrick T, Harper C, Hurd YL, Terenius L, Ekström TJ, Bakalkin G, Yakovleva T., PLoS One 2(9), 2007
PMID: 17895971

Oxidative stress and transcriptional regulation in Alzheimer disease.
Shi Q, Gibson GE., Alzheimer Dis Assoc Disord 21(4), 2007
PMID: 18090434

Dual roles of NF-kappaB in cell survival and implications of NF-kappaB inhibitors in neuroprotective therapy.
Qin ZH, Tao LY, Chen X., Acta Pharmacol Sin 28(12), 2007
PMID: 18031598

Biphasic role of nuclear factor-kappa B on cell survival and COX-2 expression in SOD1 Tg astrocytes after oxygen glucose deprivation.
Lee YS, Song YS, Giffard RG, Chan PH., J Cereb Blood Flow Metab 26(8), 2006
PMID: 16395278

Potential role of NF-kappaB in adult neural stem cells: the underrated steersman?
Widera D, Mikenberg I, Kaltschmidt B, Kaltschmidt C., Int J Dev Neurosci 24(2-3), 2006
PMID: 16413989

Low K+ promotes NF-kappaB/DNA binding in neuronal apoptosis induced by K+ loss.
Tao Y, Yan D, Yang Q, Zeng R, Wang Y., Mol Cell Biol 26(3), 2006
PMID: 16428456

Effect of Abeta exposure on the mRNA expression patterns of voltage-sensitive calcium channel alpha 1 subunits (alpha 1A-alpha 1D) in human SK-N-SH neuroblastoma.
Chiou WF., Neurochem Int 49(3), 2006
PMID: 16574279

NF-kappaB pathway: a target for preventing beta-amyloid (Abeta)-induced neuronal damage and Abeta42 production.
Valerio A, Boroni F, Benarese M, Sarnico I, Ghisi V, Bresciani LG, Ferrario M, Borsani G, Spano P, Pizzi M., Eur J Neurosci 23(7), 2006
PMID: 16623827

Effects of pyrrolidine dithiocarbamate on beta-amyloid (25-35)-induced inflammatory responses and memory deficits in the rat.
Cheng G, Whitehead SN, Hachinski V, Cechetto DF., Neurobiol Dis 23(1), 2006
PMID: 16624564

Roles for NF-kappaB in nerve cell survival, plasticity, and disease.
Mattson MP, Meffert MK., Cell Death Differ 13(5), 2006
PMID: 16397579

Pharmacological studies on fullerene (C60), a novel carbon allotrope, and its derivatives.
Satoh M, Takayanagi I., J Pharmacol Sci 100(5), 2006
PMID: 16682790

Anti-inflammatory effect of jeongshintang through suppression of p38 activation in human astrocytoma, U373MG cells.
Kim SJ, Jeong HJ, Kim BK, Kim NH, Kim JS, Choi KS, Lee HJ, Kang ST, Shin SS, Kim WI, Eom HS, Lee KM, Um JY, Hong SH, Kim HM., Exp Mol Pathol 81(1), 2006
PMID: 16698013

Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease.
Rossner S, Sastre M, Bourne K, Lichtenthaler SF., Prog Neurobiol 79(2), 2006
PMID: 16904810

Contributions of cyclooxygenase-2 to neuroplasticity and neuropathology of the central nervous system.
Hewett SJ, Bell SC, Hewett JA., Pharmacol Ther 112(2), 2006
PMID: 16750270

Distinct roles of diverse nuclear factor-kappaB complexes in neuropathological mechanisms.
Pizzi M, Spano P., Eur J Pharmacol 545(1), 2006
PMID: 16854410

Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets.
Ramassamy C., Eur J Pharmacol 545(1), 2006
PMID: 16904103

Pin1 in Alzheimer's disease.
Butterfield DA, Abdul HM, Opii W, Newman SF, Joshi G, Ansari MA, Sultana R., J Neurochem 98(6), 2006
PMID: 16945100

NF-kappaB functions in the nervous system: from development to disease.
Mémet S., Biochem Pharmacol 72(9), 2006
PMID: 16997282

Interaction of interleukin-1beta with muscarinic acetylcholine receptor-mediated signaling cascade in cholinergically differentiated SH-SY5Y cells.
Schliebs R, Heidel K, Apelt J, Gniezdzinska M, Kirazov L, Szutowicz A., Brain Res 1122(1), 2006
PMID: 17026971

The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration.
Alberghina L, Colangelo AM., BMC Neurosci 7 Suppl 1(), 2006
PMID: 17118156

Protein oxidation and degradation during aging: role in skin aging and neurodegeneration.
Widmer R, Ziaja I, Grune T., Free Radic Res 40(12), 2006
PMID: 17090415

NF-kappaB precursor, p105, and NF-kappaB inhibitor, IkappaBgamma, are both elevated in Alzheimer disease brain.
Huang Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX., Neurosci Lett 373(2), 2005
PMID: 15567564

TNF alpha potentiates glutamate neurotoxicity by inhibiting glutamate uptake in organotypic brain slice cultures: neuroprotection by NF kappa B inhibition.
Zou JY, Crews FT., Brain Res 1034(1-2), 2005
PMID: 15713255

Altered transcriptional regulators in response to serum in immortalized lymphocytes from Alzheimer's disease patients.
de las Cuevas N, Muñoz U, Hermida OG, Martín-Requero A., Neurobiol Aging 26(5), 2005
PMID: 15708436

Endogenous oxidative stress in sporadic Alzheimer's disease neuronal cybrids reduces viability by increasing apoptosis through pro-death signaling pathways and is mimicked by oxidant exposure of control cybrids.
Onyango IG, Bennett JP, Tuttle JB., Neurobiol Dis 19(1-2), 2005
PMID: 15837587

NF-kappaB in the survival and plasticity of neurons.
Mattson MP., Neurochem Res 30(6-7), 2005
PMID: 16187223

NF-kappaB factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity.
Pizzi M, Sarnico I, Boroni F, Benarese M, Steimberg N, Mazzoleni G, Dietz GP, Bähr M, Liou HC, Spano PF., Cell Death Differ 12(7), 2005
PMID: 15818410

Signaling via NF-kappaB in the nervous system.
Kaltschmidt B, Widera D, Kaltschmidt C., Biochim Biophys Acta 1745(3), 2005
PMID: 15993497

Distinct nuclear factor-kappaB/Rel proteins have opposing modulatory effects in glutamate-induced cell death in HT22 cells.
Ishige K, Tanaka M, Arakawa M, Saito H, Ito Y., Neurochem Int 47(8), 2005
PMID: 16183169

Selenium reduces the proapoptotic signaling associated to NF-kappaB pathway and stimulates glutathione peroxidase activity during excitotoxic damage produced by quinolinate in rat corpus striatum.
Santamaría A, Vázquez-Román B, La Cruz VP, González-Cortés C, Trejo-Solís MC, Galván-Arzate S, Jara-Prado A, Guevara-Fonseca J, Ali SF., Synapse 58(4), 2005
PMID: 16206188

Responses of Cultured Astrocytes, C6 Glioma and 1321NI Astrocytoma Cells to Amyloid beta-Peptide Fragments.
Pentreath VW, Mead C., Nonlinearity Biol Toxicol Med 2(1), 2004
PMID: 19330108

Effects of beta-AP peptides on activation of the transcription factor NF-kappaB and in cell proliferation in glial cell cultures.
Casal C, Serratosa J, Tusell JM., Neurosci Res 48(3), 2004
PMID: 15154677

Differential MnSOD and HO-1 expression in cerebral endothelial cells in response to sublethal oxidative stress.
Méthy D, Bertrand N, Prigent-Tessier A, Stanimirovic D, Beley A, Marie C., Brain Res 1003(1-2), 2004
PMID: 15019574

Overexpression of receptor of advanced glycation end products hypersensitizes cells for amyloid beta peptide-induced cell death.
Hadding A, Kaltschmidt B, Kaltschmidt C., Biochim Biophys Acta 1691(1), 2004
PMID: 15053925

Beta-amyloid25-35 inhibits glutamate uptake in cultured neurons and astrocytes: modulation of uptake as a survival mechanism.
Fernández-Tomé P, Brera B, Arévalo MA, de Ceballos ML., Neurobiol Dis 15(3), 2004
PMID: 15056466

Effect of cell density on intracellular levels of the Alzheimer's amyloid precursor protein.
Rebelo S, Henriques AG, da Cruz e Silva EF, da Cruz e Silva OA., J Neurosci Res 76(3), 2004
PMID: 15079870

N-Propargyl-1 (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappaB transcription factor.
Maruyama W, Nitta A, Shamoto-Nagai M, Hirata Y, Akao Y, Yodim M, Furukawa S, Nabeshima T, Naoi M., Neurochem Int 44(6), 2004
PMID: 14687604

Interference effect of epigallocatechin-3-gallate on targets of nuclear factor kappaB signal transduction pathways activated by EB virus encoded latent membrane protein 1.
Yan Z, Yong-Guang T, Fei-Jun L, Fa-Qing T, Min T, Ya C., Int J Biochem Cell Biol 36(8), 2004
PMID: 15147726

GEFT, a Rho family guanine nucleotide exchange factor, regulates neurite outgrowth and dendritic spine formation.
Bryan B, Kumar V, Stafford LJ, Cai Y, Wu G, Liu M., J Biol Chem 279(44), 2004
PMID: 15322108

RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice.
Arancio O, Zhang HP, Chen X, Lin C, Trinchese F, Puzzo D, Liu S, Hegde A, Yan SF, Stern A, Luddy JS, Lue LF, Walker DG, Roher A, Buttini M, Mucke L, Li W, Schmidt AM, Kindy M, Hyslop PA, Stern DM, Du Yan SS., EMBO J 23(20), 2004
PMID: 15457210

Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease.
Grune T, Jung T, Merker K, Davies KJ., Int J Biochem Cell Biol 36(12), 2004
PMID: 15325589

Protective effects of oligomers of grape seed polyphenols against beta-amyloid-induced oxidative cell death.
Li MH, Jang JH, Sun B, Surh YJ., Ann N Y Acad Sci 1030(), 2004
PMID: 15659813

Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: reasoning for seasoning.
Aggarwal BB, Shishodia S., Ann N Y Acad Sci 1030(), 2004
PMID: 15659827

Genes and genomics of autoimmune inflammation: from Rel to TRAIL.
Chen YH., Immunol Res 27(2-3), 2003
PMID: 12857966

Pyrrolidine dithiocarbamate-induced neuronal cell death is mediated by Akt, casein kinase 2, c-Jun N-terminal kinase, and IkappaB kinase in embryonic hippocampal progenitor cells.
Min YK, Park JH, Chong SA, Kim YS, Ahn YS, Seo JT, Bae YS, Chung KC., J Neurosci Res 71(5), 2003
PMID: 12584727

Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation.
Ghribi O, Herman MM, Savory J., J Neurosci Res 71(6), 2003
PMID: 12605412

From calcium to NF-kappa B signaling pathways in neurons.
Lilienbaum A, Israël A., Mol Cell Biol 23(8), 2003
PMID: 12665571

Mutational study of the nuclear factor kappa B inducing kinase gene in patients with progressive supranuclear palsy.
Campdelacreu J, Ezquerra M, Muñoz E, Oliva R, Tolosa E., Neurosci Lett 340(2), 2003
PMID: 12668260

Noradrenergic depletion increases inflammatory responses in brain: effects on IkappaB and HSP70 expression.
Heneka MT, Gavrilyuk V, Landreth GE, O'Banion MK, Weinberg G, Feinstein DL., J Neurochem 85(2), 2003
PMID: 12675915

H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK.
Tamagno E, Robino G, Obbili A, Bardini P, Aragno M, Parola M, Danni O., Exp Neurol 180(2), 2003
PMID: 12684028

Inhibition of NF-kB renders cells more vulnerable to apoptosis induced by amyloid beta peptides.
Cardoso SM, Oliveira CR., Free Radic Res 37(9), 2003
PMID: 14670004

Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway.
Solá S, Castro RE, Laires PA, Steer CJ, Rodrigues CM., Mol Med 9(9-12), 2003
PMID: 15208744

Amyloid beta peptide (Abeta42) activates PLC-delta1 promoter through the NF-kappaB binding site.
Kim JY, Kim H, Lee SG, Choi BH, Kim YH, Huh PW, Lee KH, Han H, Rha HK., Biochem Biophys Res Commun 310(3), 2003
PMID: 14550290

Is DNA repair compromised in Alzheimer's disease?
Davydov V, Hansen LA, Shackelford DA., Neurobiol Aging 24(7), 2003
PMID: 12928056

MK-801 and 7-Ni attenuate the activation of brain NF-kappa B induced by LPS.
Glezer I, Munhoz CD, Kawamoto EM, Marcourakis T, Avellar MC, Avellar MC, Scavone C., Neuropharmacology 45(8), 2003
PMID: 14614955

Free radicals in the physiological control of cell function.
Dröge W., Physiol Rev 82(1), 2002
PMID: 11773609

Stimulus-dependent activation of NF-kappaB specifies apoptosis or neuroprotection in cerebellar granule cells.
Kaltschmidt B, Heinrich M, Kaltschmidt C., Neuromolecular Med 2(3), 2002
PMID: 12622408

Alpha1-antichymotrypsin/Alzheimer's peptide Abeta(1-42) complex perturbs lipid metabolism and activates transcription factors PPARgamma and NFkappaB in human neuroblastoma (Kelly) cells.
Sun YX, Wright HT, Janciauskiene S., J Neurosci Res 67(4), 2002
PMID: 11835318

Water-soluble chitosan inhibits the production of pro-inflammatory cytokine in human astrocytoma cells activated by amyloid beta peptide and interleukin-1beta.
Kim MS, Sung MJ, Seo SB, Yoo SJ, Lim WK, Kim HM., Neurosci Lett 321(1-2), 2002
PMID: 11872267

[The Rel/NF-kappa-B transcription factors: complex role in cell regulation].
Bottex-Gauthier C, Pollet S, Favier A, Vidal DR., Pathol Biol (Paris) 50(3), 2002
PMID: 11980335

Growing old with nuclear factor-kappaB.
Giardina C, Hubbard AK., Cell Stress Chaperones 7(2), 2002
PMID: 12380689

NF-kappaB-mediated up-regulation of Bcl-X(S) and Bax contributes to cytochrome c release in cyanide-induced apoptosis.
Shou Y, Li N, Li L, Borowitz JL, Isom GE., J Neurochem 81(4), 2002
PMID: 12065643

Acetaminophen protects hippocampal neurons and PC12 cultures from amyloid beta-peptides induced oxidative stress and reduces NF-kappaB activation.
Bisaglia M, Venezia V, Piccioli P, Stanzione S, Porcile C, Russo C, Mancini F, Milanese C, Schettini G., Neurochem Int 41(1), 2002
PMID: 11918971

Transcriptional activation and increase in expression of Alzheimer's beta-amyloid precursor protein gene is mediated by TGF-beta in normal human astrocytes.
Burton T, Liang B, Dibrov A, Amara F., Biochem Biophys Res Commun 295(3), 2002
PMID: 12099697

Transforming growth factor-beta-induced transcription of the Alzheimer beta-amyloid precursor protein gene involves interaction between the CTCF-complex and Smads.
Burton T, Liang B, Dibrov A, Amara F., Biochem Biophys Res Commun 295(3), 2002
PMID: 12099698

Generation of reactive oxygen species and activation of NF-kappaB by non-Abeta component of Alzheimer's disease amyloid.
Tanaka S, Takehashi M, Matoh N, Iida S, Suzuki T, Futaki S, Hamada H, Masliah E, Sugiura Y, Ueda K., J Neurochem 82(2), 2002
PMID: 12124431

Nutritional approaches to combat oxidative stress in Alzheimer's disease.
Butterfield D, Castegna A, Pocernich C, Drake J, Scapagnini G, Calabrese V., J Nutr Biochem 13(8), 2002
PMID: 12165357

Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation.
Hilliard BA, Mason N, Xu L, Sun J, Lamhamedi-Cherradi SE, Liou HC, Hunter C, Chen YH., J Clin Invest 110(6), 2002
PMID: 12235116

Abeta[25-35] peptide and iron promote apoptosis in lymphocytes by an oxidative stress mechanism: involvement of H2O2, caspase-3, NF-kappaB, p53 and c-Jun.
Velez-Pardo C, Ospina GG, Jimenez del Rio M., Neurotoxicology 23(3), 2002
PMID: 12387362

NF-kappaB mediates IL-1beta-induced synthesis/release of alpha2-macroglobulin in a human glial cell line.
Gao F, Bales KR, Dodel RC, Liu J, Chen X, Hample H, Farlow MR, Paul SM, Du Y., Brain Res Mol Brain Res 105(1-2), 2002
PMID: 12399113

Hypoxia signaling to genes: significance in Alzheimer's disease.
Bazan NG, Palacios-Pelaez R, Lukiw WJ., Mol Neurobiol 26(2-3), 2002
PMID: 12428761

Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide.
Rogers J, Strohmeyer R, Kovelowski CJ, Li R., Glia 40(2), 2002
PMID: 12379913

Oxidative modulation of nuclear factor-kappaB in human cells expressing mutant fALS-typical superoxide dismutases.
Casciati A, Ferri A, Cozzolino M, Celsi F, Nencini M, Rotilio G, Carrì MT., J Neurochem 83(5), 2002
PMID: 12437573

Cyclooxygenase-2 is a neuronal target gene of NF-kappaB.
Kaltschmidt B, Linker RA, Deng J, Kaltschmidt C., BMC Mol Biol 3(), 2002
PMID: 12466023

Neuroprotection from glutamate toxicity with ultra-low dose glutamate.
Jonas W, Lin Y, Tortella F., Neuroreport 12(2), 2001
PMID: 11209946

Hippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure.
Lucassen PJ, Müller MB, Holsboer F, Bauer J, Holtrop A, Wouda J, Hoogendijk WJ, De Kloet ER, Swaab DF., Am J Pathol 158(2), 2001
PMID: 11159183

Amyloid beta-peptide disrupts mitochondrial membrane lipid and protein structure: protective role of tauroursodeoxycholate.
Rodrigues CM, Solá S, Brito MA, Brondino CD, Brites D, Moura JJ., Biochem Biophys Res Commun 281(2), 2001
PMID: 11181071

NF-kappaB is involved in the survival of cerebellar granule neurons: association of IkappaBbeta [correction of Ikappabeta] phosphorylation with cell survival.
Koulich E, Nguyen T, Johnson K, Giardina C, D'mello S., J Neurochem 76(4), 2001
PMID: 11181838

DNA array analysis of the developing rat cerebellum: transforming growth factor-beta2 inhibits constitutively activated NF-kappaB in granule neurons.
Kaltschmidt B, Kaltschmidt C., Mech Dev 101(1-2), 2001
PMID: 11231055

Intracellular pathways involved in TNF-alpha and superoxide anion release by Abeta(1-42)-stimulated primary human macrophages.
Smits HA, de Vos NM, Wat JW, van der Bruggen T, Verhoef J, Nottet HS., J Neuroimmunol 115(1-2), 2001
PMID: 11282164

Nuclear factor-kappaB activation is not involved in a MPTP model of Parkinson's disease.
Teismann P, Schwaninger M, Weih F, Ferger B., Neuroreport 12(5), 2001
PMID: 11303744

Mitochondrial involvement in brain function and dysfunction: relevance to aging, neurodegenerative disorders and longevity.
Calabrese V, Scapagnini G, Giuffrida Stella AM, Bates TE, Clark JB., Neurochem Res 26(6), 2001
PMID: 11519733

C-terminal fragment of amyloid precursor protein induces astrocytosis.
Bach JH, Chae HS, Rah JC, Lee MW, Park CH, Choi SH, Choi JK, Lee SH, Kim YS, Kim KY, Lee WB, Suh YH, Kim SS., J Neurochem 78(1), 2001
PMID: 11432978

Amyloid beta-peptide: biphasic dose responses.
Calabrese EJ., Crit Rev Toxicol 31(4-5), 2001
PMID: 11504184

From theory to therapy: implications from an in vitro model of ramified microglia.
Rosenstiel P, Lucius R, Deuschl G, Sievers J, Wilms H., Microsc Res Tech 54(1), 2001
PMID: 11526952

6-hydroxydopamine-induced nuclear factor-kappa B activation in PC12 cells.
Blum D, Torch S, Nissou MF, Verna JM., Biochem Pharmacol 62(4), 2001
PMID: 11448458

The amyloid peptide induces early genotoxic damage in human preneuron NT2.
Santiard-Baron D, Lacoste A, Ellouk-Achard S, Soulié C, Nicole A, Sarasin A, Ceballos-Picot I., Mutat Res 479(1-2), 2001
PMID: 11470486

Preconditioning-induced neuroprotection is mediated by reactive oxygen species and activation of the transcription factor nuclear factor-kappaB.
Ravati A, Ahlemeyer B, Becker A, Klumpp S, Krieglstein J., J Neurochem 78(4), 2001
PMID: 11520911

Enhanced expression of I-kappaB with neurofibrillary pathology in Alzheimer's disease.
Yoshiyama Y, Arai K, Hattori T., Neuroreport 12(12), 2001
PMID: 11522940

Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease.
Blum D, Torch S, Lambeng N, Nissou M, Benabid AL, Sadoul R, Verna JM., Prog Neurobiol 65(2), 2001
PMID: 11403877

Microglial chemotaxis, activation, and phagocytosis of amyloid beta-peptide as linked phenomena in Alzheimer's disease.
Rogers J, Lue LF., Neurochem Int 39(5-6), 2001
PMID: 11578768

Abeta(1-42) and aluminum induce stress in the endoplasmic reticulum in rabbit hippocampus, involving nuclear translocation of gadd 153 and NF-kappaB.
Ghribi O, Herman MM, DeWitt DA, Forbes MS, Savory J., Brain Res Mol Brain Res 96(1-2), 2001
PMID: 11731006

Altered subcellular distribution of transcriptional regulators in response to Abeta peptide and during Alzheimer's disease.
Jordan-Sciutto K, Rhodes J, Bowser R., Mech Ageing Dev 123(1), 2001
PMID: 11640947

S100beta induction of the proinflammatory cytokine interleukin-6 in neurons.
Li Y, Barger SW, Liu L, Mrak RE, Griffin WS., J Neurochem 74(1), 2000
PMID: 10617115

Overexpression of neurotrophin receptor p75 contributes to the excitotoxin-induced cholinergic neuronal death in rat basal forebrain.
Oh JD, Chartisathian K, Chase TN, Butcher LL., Brain Res 853(2), 2000
PMID: 10640615

Model for aging in the basal forebrain cholinergic system.
Gu Z, Wortwein G, Yu J, Perez-Polo JR., Antioxid Redox Signal 2(3), 2000
PMID: 11229357

Roles of nuclear factor kappaB in neuronal survival and plasticity.
Mattson MP, Culmsee C, Yu Z, Camandola S., J Neurochem 74(2), 2000
PMID: 10646495

Neuron-specific localisation of the TR3 death receptor in Alzheimer's disease.
Newman SJ, Bond B, Crook B, Darker J, Edge C, Maycox PR., Brain Res 857(1-2), 2000
PMID: 10700560

Transcription factor nuclear factor-kappa B is activated in neurons after focal cerebral ischemia.
Stephenson D, Yin T, Smalstig EB, Hsu MA, Panetta J, Little S, Clemens J., J Cereb Blood Flow Metab 20(3), 2000
PMID: 10724123

Cyanide-induced apoptosis involves oxidative-stress-activated NF-kappaB in cortical neurons.
Shou Y, Gunasekar PG, Borowitz JL, Isom GE., Toxicol Appl Pharmacol 164(2), 2000
PMID: 10764633

Anti-inflammatory drugs: a hope for Alzheimer's disease?
Hüll M, Lieb K, Fiebich BL., Expert Opin Investig Drugs 9(4), 2000
PMID: 11060701

The heat shock response inhibits NF-kappaB activation, nitric oxide synthase type 2 expression, and macrophage/microglial activation in brain.
Heneka MT, Sharp A, Klockgether T, Gavrilyuk V, Feinstein DL., J Cereb Blood Flow Metab 20(5), 2000
PMID: 10826530

Inflammation and Alzheimer's disease.
Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, Cooper NR, Eikelenboom P, Emmerling M, Fiebich BL, Finch CE, Frautschy S, Griffin WS, Hampel H, Hull M, Landreth G, Lue L, Mrak R, Mackenzie IR, McGeer PL, O'Banion MK, Pachter J, Pasinetti G, Plata-Salaman C, Rogers J, Rydel R, Shen Y, Streit W, Strohmeyer R, Tooyoma I, Van Muiswinkel FL, Veerhuis R, Walker D, Webster S, Wegrzyniak B, Wenk G, Wyss-Coray T., Neurobiol Aging 21(3), 2000
PMID: 10858586

The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus.
Kaltschmidt B, Kaltschmidt C, Hofmann TG, Hehner SP, Dröge W, Schmitz ML., Eur J Biochem 267(12), 2000
PMID: 10849002

Pro-apoptotic action of PAR-4 involves inhibition of NF-kappaB activity and suppression of BCL-2 expression.
Camandola S, Mattson MP., J Neurosci Res 61(2), 2000
PMID: 10878585

beta-amyloid peptides are cytotoxic to astrocytes in culture: a role for oxidative stress.
Brera B, Serrano A, de Ceballos ML., Neurobiol Dis 7(4), 2000
PMID: 10964610

The Rel/NF-kappa B family: friend and foe.
Perkins ND., Trends Biochem Sci 25(9), 2000
PMID: 10973057

Neuroinflammatory signaling upregulation in Alzheimer's disease.
Lukiw WJ, Bazan NG., Neurochem Res 25(9-10), 2000
PMID: 11059791

NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: the role of oxidant/antioxidant balance.
Calabrese V, Bates TE, Stella AM., Neurochem Res 25(9-10), 2000
PMID: 11059804

Interleukin-1beta induces cyclooxygenase-2 and prostaglandin E(2) synthesis in human neuroblastoma cells: involvement of p38 mitogen-activated protein kinase and nuclear factor-kappaB.
Fiebich BL, Mueksch B, Boehringer M, Hüll M., J Neurochem 75(5), 2000
PMID: 11032891

Dehydroepiandrosterone inhibits microglial nitric oxide production in a stimulus-specific manner.
Barger SW, Chavis JA, Drew PD., J Neurosci Res 62(4), 2000
PMID: 11070493

The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer's disease.
Miranda S, Opazo C, Larrondo LF, Muñoz FJ, Ruiz F, Leighton F, Inestrosa NC., Prog Neurobiol 62(6), 2000
PMID: 10880853

NF-kappaB transcription factors: critical regulators of hematopoiesis and neuronal survival.
Denk A, Wirth T, Baumann B., Cytokine Growth Factor Rev 11(4), 2000
PMID: 10959078

Association of a haplotype for tumor necrosis factor in siblings with late-onset Alzheimer disease: the NIMH Alzheimer Disease Genetics Initiative.
Collins JS, Perry RT, Watson B, Harrell LE, Acton RT, Blacker D, Albert MS, Tanzi RE, Bassett SS, McInnis MG, Campbell RD, Go RC., Am J Med Genet 96(6), 2000
PMID: 11121190

Differential induction of NF-kappaB activity and neural cell death by antidepressants in vitro.
Post A, Crochemore C, Uhr M, Holsboer F, Behl C., Eur J Neurosci 12(12), 2000
PMID: 11122343

The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons.
Camandola S, Poli G, Mattson MP., Brain Res Mol Brain Res 85(1-2), 2000
PMID: 11146106

Tumor necrosis factor and reactive oxygen species cooperative cytotoxicity is mediated via inhibition of NF-kappaB.
Ginis I, Hallenbeck JM, Liu J, Spatz M, Jaiswal R, Shohami E., Mol Med 6(12), 2000
PMID: 11474119

Activation of NF-kappa B by reactive oxygen intermediates in the nervous system.
Kaltschmidt B, Sparna T, Kaltschmidt C., Antioxid Redox Signal 1(2), 1999
PMID: 11228742

Nuclear factor-kappaB/Rel proteins: a point of convergence of signalling pathways relevant in neuronal function and dysfunction.
Grilli M, Memo M., Biochem Pharmacol 57(1), 1999
PMID: 9920279

Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches.
Behl C., Prog Neurobiol 57(3), 1999
PMID: 10096843

Regulation of amyloid precursor protein cleavage.
Mills J, Reiner PB., J Neurochem 72(2), 1999
PMID: 9930716

Activation of nuclear factor-kappaB in the rat brain after transient focal ischemia.
Gabriel C, Justicia C, Camins A, Planas AM., Brain Res Mol Brain Res 65(1), 1999
PMID: 10036308

Mechanisms of apoptosis in PC12 cells irreversibly differentiated with nerve growth factor and cyclic AMP.
Lambeng N, Michel PP, Brugg B, Agid Y, Ruberg M., Brain Res 821(1), 1999
PMID: 10064788

Characterization of a neuronal kappaB-binding factor distinct from NF-kappaB.
Moerman AM, Mao X, Lucas MM, Barger SW., Brain Res Mol Brain Res 67(2), 1999
PMID: 10216229

The amino-terminus of the amyloid-beta protein is critical for the cellular binding and consequent activation of the respiratory burst of human macrophages.
Van Muiswinkel FL, Raupp SF, de Vos NM, Smits HA, Verhoef J, Eikelenboom P, Nottet HS., J Neuroimmunol 96(1), 1999
PMID: 10227431

NF-kappaB is activated and promotes cell death in focal cerebral ischemia.
Schneider A, Martin-Villalba A, Weih F, Vogel J, Wirth T, Schwaninger M., Nat Med 5(5), 1999
PMID: 10229233

Repression of NF-kappaB impairs HeLa cell proliferation by functional interference with cell cycle checkpoint regulators.
Kaltschmidt B, Kaltschmidt C, Hehner SP, Dröge W, Schmitz ML., Oncogene 18(21), 1999
PMID: 10359527

Loss of NF-kappaB activity during cerebral ischemia and TNF cytotoxicity.
Botchkina GI, Geimonen E, Bilof ML, Villarreal O, Tracey KJ., Mol Med 5(6), 1999
PMID: 10415162

Anti-inflammatory substances - a new therapeutic option in Alzheimer's disease.
Hüll M, Fiebich BL, Schumann G, Lieb K, Bauer J., Drug Discov Today 4(6), 1999
PMID: 10354542

Activation of nuclear factor kappaB by nitric oxide in rat striatal neurones: differential inhibition of the p50 and p65 subunits by dexamethasone.
Simpson CS, Morris BJ., J Neurochem 73(1), 1999
PMID: 10386988

Is NF-kappaB the sensor of oxidative stress?
Li N, Karin M., FASEB J 13(10), 1999
PMID: 10385605

Differential regulation of major histocompatibility complex class II expression and nitric oxide release by beta-amyloid in rat astrocyte and microglia.
Pazmany T, Mechtler L, Tomasi TB, Kosa JP, Turoczi A, Urbanyi Z., Brain Res 835(2), 1999
PMID: 10415376

Identification of beta-amyloid-responsive genes by RNA differential display: early induction of a DNA damage-inducible gene, gadd45.
Santiard-Baron D, Gosset P, Nicole A, Sinet PM, Christen Y, Ceballos-Picot I., Exp Neurol 158(1), 1999
PMID: 10448433

Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis.
Kaltschmidt B, Uherek M, Wellmann H, Volk B, Kaltschmidt C., Proc Natl Acad Sci U S A 96(16), 1999
PMID: 10430956

cDNA cloning of a novel secreted isoform of the human receptor for advanced glycation end products and characterization of cells co-expressing cell-surface scavenger receptors and Swedish mutant amyloid precursor protein.
Malherbe P, Richards JG, Gaillard H, Thompson A, Diener C, Schuler A, Huber G., Brain Res Mol Brain Res 71(2), 1999
PMID: 10521570

Sodium salicylate and 17beta-estradiol attenuate nuclear transcription factor NF-kappaB translocation in cultured rat astroglial cultures following exposure to amyloid A beta(1-40) and lipopolysaccharides.
Dodel RC, Du Y, Bales KR, Gao F, Paul SM., J Neurochem 73(4), 1999
PMID: 10501189

Optimized protocol for biolistic transfection of brain slices and dissociated cultured neurons with a hand-held gene gun.
Wellmann H, Kaltschmidt B, Kaltschmidt C., J Neurosci Methods 92(1-2), 1999
PMID: 10595703

Interleukin-17 stimulates the expression of IkappaB alpha mRNA and the secretion of IL-6 and IL-8 in glioblastoma cell lines.
Kehlen A, Thiele K, Riemann D, Rainov N, Langner J., J Neuroimmunol 101(1), 1999
PMID: 10580807

Expression of cytokine genes and increased nuclear factor-kappa B activity in the brains of scrapie-infected mice.
Kim JI, Ju WK, Choi JH, Choi E, Carp RI, Wisniewski HM, Kim YS., Brain Res Mol Brain Res 73(1-2), 1999
PMID: 10581394

Control of apoptosis by Rel/NF-kappaB transcription factors.
Barkett M, Gilmore TD., Oncogene 18(49), 1999
PMID: 10602466

Alzheimer's disease and brain development: common molecular pathways.
Jordan-Sciutto K, Bowser R., Front Biosci 3(), 1998
PMID: 9422711

Early glycoxidation damage in brains from Down's syndrome.
Odetti P, Angelini G, Dapino D, Zaccheo D, Garibaldi S, Dagna-Bricarelli F, Piombo G, Perry G, Smith M, Traverso N, Tabaton M., Biochem Biophys Res Commun 243(3), 1998
PMID: 9501012

NF-kappaB modulates lipopolysaccharide-induced microglial nerve growth factor expression.
Heese K, Fiebich BL, Bauer J, Otten U., Glia 22(4), 1998
PMID: 9517572

Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism.
Akama KT, Albanese C, Pestell RG, Van Eldik LJ., Proc Natl Acad Sci U S A 95(10), 1998
PMID: 9576964

NF-kB immunoreactivity is observed in association with beta A4 diffuse plaques in patients with Alzheimer's disease.
Ferrer I, Martí E, López E, Tortosa A., Neuropathol Appl Neurobiol 24(4), 1998
PMID: 9775392

Upregulation of amyloid precursor protein gene promoter in rat primary hippocampal neurons by phorbol ester, IL-1 and retinoic acid, but not by reactive oxygen species.
Yang Y, Quitschke WW, Brewer GJ., Brain Res Mol Brain Res 60(1), 1998
PMID: 9748493

Immunolocalization of transcription factor NF-kappaB in inclusion-body myositis muscle and at normal human neuromuscular junctions.
Yang CC, Askanas V, Engel WK, Alvarez RB., Neurosci Lett 254(2), 1998
PMID: 9779924

Expression of FAC1 in activated microglia during Alzheimer's disease.
Bowser R, Reilly S., Neurosci Lett 253(3), 1998
PMID: 9792236

The expression of key oxidative stress-handling genes in different brain regions in Alzheimer's disease.
Aksenov MY, Tucker HM, Nair P, Aksenova MV, Butterfield DA, Estus S, Markesbery WR., J Mol Neurosci 11(2), 1998
PMID: 10096042

Familial Alzheimer's disease: oxidative stress, beta-amyloid, presenilins, and cell death.
Velez-Pardo C, Jimenez Del Rio M, Lopera F., Gen Pharmacol 31(5), 1998
PMID: 9809462

Nuclear factor kappa B: important transcription factor and therapeutic target.
Lee JI, Burckart GJ., J Clin Pharmacol 38(11), 1998
PMID: 9824778

NF-kappa B: a crucial transcription factor for glial and neuronal cell function.
O'Neill LA, Kaltschmidt C., Trends Neurosci 20(6), 1997
PMID: 9185306

Gene expression induced by cerebral ischemia: an apoptotic perspective.
MacManus JP, Linnik MD., J Cereb Blood Flow Metab 17(8), 1997
PMID: 9290580

Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration.
Mattson MP, Goodman Y, Luo H, Fu W, Furukawa K., J Neurosci Res 49(6), 1997
PMID: 9335256

Antioxidant defense of the brain: a role for astrocytes.
Wilson JX., Can J Physiol Pharmacol 75(10-11), 1997
PMID: 9431439

Alteration of transcription factors NF-kappaB and STAT1 in Alzheimer's disease brains.
Kitamura Y, Shimohama S, Ota T, Matsuoka Y, Nomura Y, Taniguchi T., Neurosci Lett 237(1), 1997
PMID: 9406869

49 References

Daten bereitgestellt von Europe PubMed Central.

Vitamin E protects nerve cells from amyloid beta protein toxicity.
Behl C, Davis J, Cole GM, Schubert D., Biochem. Biophys. Res. Commun. 186(2), 1992
PMID: 1497677

The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-kappa B.
Schmidt KN, Amstad P, Cerutti P, Baeuerle PA., Chem. Biol. 2(1), 1995
PMID: 9383399

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway.
Sun SC, Ganchi PA, Ballard DW, Greene WC., Science 259(5103), 1993
PMID: 8096091

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.
Meyer M, Schreck R, Baeuerle PA., EMBO J. 12(5), 1993
PMID: 8491191

Amyloid beta-protein activates tachykinin receptors and inositol trisphosphate accumulation by synergy with glutamate.
Kimura H, Schubert D., Proc. Natl. Acad. Sci. U.S.A. 90(16), 1993
PMID: 7689220

Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B.
Henkel T, Machleidt T, Alkalay I, Kronke M, Ben-Neriah Y, Baeuerle PA., Nature 365(6442), 1993
PMID: 8371761

Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6.
Campbell IL, Abraham CR, Masliah E, Kemper P, Inglis JD, Oldstone MB, Mucke L., Proc. Natl. Acad. Sci. U.S.A. 90(21), 1993
PMID: 7694279

Oxidative stress, glutamate, and neurodegenerative disorders.
Coyle JT, Puttfarcken P., Science 262(5134), 1993
PMID: 7901908

Accumulation of intercellular adhesion molecule-1 in senile plaques in brain tissue of patients with Alzheimer's disease.
Verbeek MM, Otte-Holler I, Westphal JR, Wesseling P, Ruiter DJ, de Waal RM., Am. J. Pathol. 144(1), 1994
PMID: 7904796

Localization of Alzheimer beta A4 amyloid precursor protein at central and peripheral synaptic sites.
Schubert W, Prior R, Weidemann A, Dircksen H, Multhaup G, Masters CL, Beyreuther K., Brain Res. 563(1-2), 1991
PMID: 1786532

Cytokine regulation of interleukin-6 gene expression in astrocytes involves activation of an NF-kappa B-like nuclear protein.
Sparacio SM, Zhang Y, Vilcek J, Benveniste EN., J. Neuroimmunol. 39(3), 1992
PMID: 1644898

Brain synapses contain inducible forms of the transcription factor NF-kappa B.
Kaltschmidt C, Kaltschmidt B, Baeuerle PA., Mech. Dev. 43(2-3), 1993
PMID: 8297787

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease.
Hensley K, Carney JM, Mattson MP, Aksenova M, Harris M, Wu JF, Floyd RA, Butterfield DA., Proc. Natl. Acad. Sci. U.S.A. 91(8), 1994
PMID: 8159737

Constitutive NF-kappa B activity in neurons.
Kaltschmidt C, Kaltschmidt B, Neumann H, Wekerle H, Baeuerle PA., Mol. Cell. Biol. 14(6), 1994
PMID: 8196637

Hydrogen peroxide mediates amyloid beta protein toxicity.
Behl C, Davis JB, Lesley R, Schubert D., Cell 77(6), 1994
PMID: 8004671

Function and activation of NF-kappa B in the immune system.
Baeuerle PA, Henkel T., Annu. Rev. Immunol. 12(), 1994
PMID: 8011280

Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation.
Liou HC, Sha WC, Scott ML, Baltimore D., Mol. Cell. Biol. 14(8), 1994
PMID: 8035813

Inflammatory mechanisms in Alzheimer's disease: implications for therapy.
Aisen PS, Davis KL., Am J Psychiatry 151(8), 1994
PMID: 7518651

Expression of inducible nitric oxide synthase by neurones following exposure to endotoxin and cytokine.
Minc-Golomb D, Tsarfaty I, Schwartz JP., Br. J. Pharmacol. 112(3), 1994
PMID: 7522856

Transcription factor NF-kappa B is activated in microglia during experimental autoimmune encephalomyelitis.
Kaltschmidt C, Kaltschmidt B, Lannes-Vieira J, Kreutzberg GW, Wekerle H, Baeuerle PA, Gehrmann J., J. Neuroimmunol. 55(1), 1994
PMID: 7962486

Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene.
Muller U, Cristina N, Li ZW, Wolfer DP, Lipp HP, Rulicke T, Brandner S, Aguzzi A, Weissmann C., Cell 79(5), 1994
PMID: 8001115

Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein.
Games D, Adams D, Alessandrini R, Barbour R, Berthelette P, Blackwell C, Carr T, Clemens J, Donaldson T, Gillespie F., Nature 373(6514), 1995
PMID: 7845465

Interleukin-1 expression in different plaque types in Alzheimer's disease: significance in plaque evolution.
Griffin WS, Sheng JG, Roberts GW, Mrak RE., J. Neuropathol. Exp. Neurol. 54(2), 1995
PMID: 7876895

Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ.
Lassmann H, Bancher C, Breitschopf H, Wegiel J, Bobinski M, Jellinger K, Wisniewski HM., Acta Neuropathol. 89(1), 1995
PMID: 7709729

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity.
Zheng H, Jiang M, Trumbauer ME, Sirinathsinghji DJ, Hopkins R, Smith DW, Heavens RP, Dawson GR, Boyce S, Conner MW, Stevens KA, Slunt HH, Sisoda SS, Chen HY, Van der Ploeg LH., Cell 81(4), 1995
PMID: 7758106

Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and beta-amyloid production in cultures.
Del Bo R, Angeretti N, Lucca E, De Simoni MG, Forloni G., Neurosci. Lett. 188(1), 1995
PMID: 7783982

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B.
Beg AA, Sha WC, Bronson RT, Ghosh S, Baltimore D., Nature 376(6536), 1995
PMID: 7603567

Selective recognition of the activated form of transcription factor NF-kappa B by a monoclonal antibody.
Kaltschmidt C, Kaltschmidt B, Henkel T, Stockinger H, Baeuerle PA., Biol. Chem. Hoppe-Seyler 376(1), 1995
PMID: 7612189

Induction of MHC class I genes in neurons.
Neumann H, Cavalie A, Jenne DE, Wekerle H., Science 269(5223), 1995
PMID: 7624779

Glial cytokines in Alzheimer's disease: review and pathogenic implications.
Mrak RE, Sheng JG, Griffin WS., Hum. Pathol. 26(8), 1995
PMID: 7635444

Stimulation of ionotropic glutamate receptors activates transcription factor NF-kappa B in primary neurons.
Kaltschmidt C, Kaltschmidt B, Baeuerle PA., Proc. Natl. Acad. Sci. U.S.A. 92(21), 1995
PMID: 7568184

Synaptic activation of NF-kappa B by glutamate in cerebellar granule neurons in vitro.
Guerrini L, Blasi F, Denis-Donini S., Proc. Natl. Acad. Sci. U.S.A. 92(20), 1995
PMID: 7568076

Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.
Barger SW, Horster D, Furukawa K, Goodman Y, Krieglstein J, Mattson MP., Proc. Natl. Acad. Sci. U.S.A. 92(20), 1995
PMID: 7568127

Identification and characterization of a kappa B/Rel binding site in the regulatory region of the amyloid precursor protein gene.
Grilli M, Ribola M, Alberici A, Valerio A, Memo M, Spano P., J. Biol. Chem. 270(45), 1995
PMID: 7592914

Induction of oxidative stress by okadaic acid is required for activation of transcription factor NF-kappa B.
Schmidt KN, Traenckner EB, Meier B, Baeuerle PA., J. Biol. Chem. 270(45), 1995
PMID: 7592968

Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein.
Glenner GG, Wong CW., Biochem. Biophys. Res. Commun. 120(3), 1984
PMID: 6375662

Amyloid plaque core protein in Alzheimer disease and Down syndrome.
Masters CL, Simms G, Weinman NA, Multhaup G, McDonald BL, Beyreuther K., Proc. Natl. Acad. Sci. U.S.A. 82(12), 1985
PMID: 3159021

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor.
Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, Multhaup G, Beyreuther K, Muller-Hill B., Nature 325(6106), 1987
PMID: 2881207

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides.
Yankner BA, Duffy LK, Kirschner DA., Science 250(4978), 1990
PMID: 2218531

Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus.
Staal FJ, Roederer M, Herzenberg LA, Herzenberg LA., Proc. Natl. Acad. Sci. U.S.A. 87(24), 1990
PMID: 2263644

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage.
Koh JY, Yang LL, Cotman CW., Brain Res. 533(2), 1990
PMID: 2289145

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.
Schreck R, Rieber P, Baeuerle PA., EMBO J. 10(8), 1991
PMID: 2065663

Is amyloidogenesis during Alzheimer's disease due to an IL-1-/IL-6-mediated 'acute phase response' in the brain?
Vandenabeele P, Fiers W., Immunol. Today 12(7), 1991
PMID: 1909530

Detection of interleukin-6 and alpha 2-macroglobulin immunoreactivity in cortex and hippocampus of Alzheimer's disease patients.
Strauss S, Bauer J, Ganter U, Jonas U, Berger M, Volk B., Lab. Invest. 66(2), 1992
PMID: 1370967

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.
Verma IM, Stevenson JK, Schwarz EM, Van Antwerp D, Miyamoto S., Genes Dev. 9(22), 1995
PMID: 7590248

Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.
Carter BD, Kaltschmidt C, Kaltschmidt B, Offenhauser N, Bohm-Matthaei R, Baeuerle PA, Barde YA., Science 272(5261), 1996
PMID: 8614802

TrkA activation is sufficient to rescue axotomized cholinergic neurons.
Lucidi-Phillipi CA, Clary DO, Reichardt LF, Gage FH., Neuron 16(3), 1996
PMID: 8785062

Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells.
Li ZW, Stark G, Gotz J, Rulicke T, Gschwind M, Huber G, Muller U, Weissmann C., Proc. Natl. Acad. Sci. U.S.A. 93(12), 1996
PMID: 8650236

The NF-kappa B p65 promoter.
Ueberla K, Lu Y, Chung E, Haseltine WA., J. Acquir. Immune Defic. Syndr. 6(3), 1993
PMID: 8450395

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 9122249
PubMed | Europe PMC

Suchen in

Google Scholar

PUB - Publikationen an der Universität Bielefeld