Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion

Brand K, Page S, Rogler G, Bartsch A, Brandl R, Knuechel R, Page M, Kaltschmidt C, Baeurle PA, Neumeier D (1996)
J. Clin. Invest. 97(7): 1715-1722.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Brand, K.; Page, S.; Rogler, G.; Bartsch, A.; Brandl, R.; Knuechel, R.; Page, M.; Kaltschmidt, ChristianUniBi; Baeurle, P.A.; Neumeier, D.
J. Clin. Invest.
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Brand K, Page S, Rogler G, et al. Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J. Clin. Invest. 1996;97(7):1715-1722.
Brand, K., Page, S., Rogler, G., Bartsch, A., Brandl, R., Knuechel, R., Page, M., et al. (1996). Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J. Clin. Invest., 97(7), 1715-1722.
Brand, K., Page, S., Rogler, G., Bartsch, A., Brandl, R., Knuechel, R., Page, M., Kaltschmidt, Christian, Baeurle, P.A., and Neumeier, D. 1996. “Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion”. J. Clin. Invest. 97 (7): 1715-1722.
Brand, K., Page, S., Rogler, G., Bartsch, A., Brandl, R., Knuechel, R., Page, M., Kaltschmidt, C., Baeurle, P. A., and Neumeier, D. (1996). Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J. Clin. Invest. 97, 1715-1722.
Brand, K., et al., 1996. Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J. Clin. Invest., 97(7), p 1715-1722.
K. Brand, et al., “Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion”, J. Clin. Invest., vol. 97, 1996, pp. 1715-1722.
Brand, K., Page, S., Rogler, G., Bartsch, A., Brandl, R., Knuechel, R., Page, M., Kaltschmidt, C., Baeurle, P.A., Neumeier, D.: Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J. Clin. Invest. 97, 1715-1722 (1996).
Brand, K., Page, S., Rogler, G., Bartsch, A., Brandl, R., Knuechel, R., Page, M., Kaltschmidt, Christian, Baeurle, P.A., and Neumeier, D. “Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion”. J. Clin. Invest. 97.7 (1996): 1715-1722.

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Molecular inflammation: underpinnings of aging and age-related diseases.
Chung HY, Cesari M, Anton S, Marzetti E, Giovannini S, Seo AY, Carter C, Yu BP, Leeuwenburgh C., Ageing Res Rev 8(1), 2009
PMID: 18692159
Cilostazol inhibits cytokine-induced nuclear factor-kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells.
Hattori Y, Suzuki K, Tomizawa A, Hirama N, Okayasu T, Hattori S, Satoh H, Akimoto K, Kasai K., Cardiovasc Res 81(1), 2009
PMID: 18703532
Activation of transcription factors and gene expression by oxidized low-density lipoprotein.
Mazière C, Mazière JC., Free Radic Biol Med 46(2), 2009
PMID: 18996472
The role of RAGE in aminoguanidine-induced suppression of venous intimal hyperplasia in diabetic rats.
Wang X, Diao Y, Zhang H, Huo X, Zhang Q., Ann Vasc Surg 23(2), 2009
PMID: 19110400
Insulin-like growth factor-1 receptor expression masks the antiinflammatory and glucose uptake capacity of insulin in vascular smooth muscle cells.
Engberding N, San Martín A, Martin-Garrido A, Koga M, Pounkova L, Lyons E, Lassègue B, Griendling KK., Arterioscler Thromb Vasc Biol 29(3), 2009
PMID: 19122171
Nanoparticle-mediated delivery of nuclear factor kappaB decoy into lungs ameliorates monocrotaline-induced pulmonary arterial hypertension.
Kimura S, Egashira K, Chen L, Nakano K, Iwata E, Miyagawa M, Tsujimoto H, Hara K, Morishita R, Sueishi K, Tominaga R, Sunagawa K., Hypertension 53(5), 2009
PMID: 19307469
Induction of MIF expression by oxidized LDL via activation of NF-kappaB in vascular smooth muscle cells.
Chen L, Yang G, Zhang X, Wu J, Gu Q, Wei M, Yang J, Zhu Y, Wang N, Guan Y., Atherosclerosis 207(2), 2009
PMID: 19640536
Considering TWEAK as a target for therapy in renal and vascular injury.
Ortiz A, Sanz AB, Muñoz García B, Moreno JA, Sánchez Niño MD, Martín-Ventura JL, Egido J, Blanco-Colio LM., Cytokine Growth Factor Rev 20(3), 2009
PMID: 19482507
Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes.
Newby AC, George SJ, Ismail Y, Johnson JL, Sala-Newby GB, Thomas AC., Thromb Haemost 101(6), 2009
PMID: 19492140
Nuclear factor-kappaB regulates estrogen receptor-alpha transcription in the human heart.
Mahmoodzadeh S, Fritschka S, Dworatzek E, Pham TH, Becher E, Kuehne A, Davidson MM, Regitz-Zagrosek V., J Biol Chem 284(37), 2009
PMID: 19584059
RAGE, vascular tone and vascular disease.
Farmer DG, Kennedy S., Pharmacol Ther 124(2), 2009
PMID: 19616578
Importance of pericytes and mechanisms of pericyte loss during diabetes retinopathy.
Ejaz S, Chekarova I, Ejaz A, Sohail A, Lim CW., Diabetes Obes Metab 10(1), 2008
PMID: 17941874
Homocysteine stimulates monocyte chemoattractant protein-1 expression in the kidney via nuclear factor-kappaB activation.
Hwang SY, Woo CW, Au-Yeung KK, Siow YL, Zhu TY, O K., Am J Physiol Renal Physiol 294(1), 2008
PMID: 17977907
Bioactive lipids in metabolic syndrome.
Nagao K, Yanagita T., Prog Lipid Res 47(2), 2008
PMID: 18177744
Proinsulin C-peptide: friend or foe in the development of diabetes-associated complications?
Nordquist L, Johansson M., Vasc Health Risk Manag 4(6), 2008
PMID: 19337542
Possible role of NFkappaB in the embryonic vascular remodeling and the endothelial mesenchymal transition process.
Arciniegas E, Carrillo LM, De Sanctis JB, Candelle D., Cell Adh Migr 2(1), 2008
PMID: 19262121
The profile of gene expression and role of nuclear factor kappa B on glomerular injury in rats with Thy-1 nephritis.
Wang H, Jiang XM, Xu JH, Xu J, Tong JX, Wang YW., Clin Exp Immunol 152(3), 2008
PMID: 18422731
p21-activated kinase signaling regulates oxidant-dependent NF-kappa B activation by flow.
Orr AW, Hahn C, Blackman BR, Schwartz MA., Circ Res 103(6), 2008
PMID: 18669917
Endothelial dysfunction: from molecular mechanisms to measurement, clinical implications, and therapeutic opportunities.
Le Brocq M, Leslie SJ, Milliken P, Megson IL., Antioxid Redox Signal 10(9), 2008
PMID: 18598143
Homocysteine-induced enhanced expression of tissue factor in human vascular smooth muscle cells.
Liu F, Huang R, Yao J, Wei W, Hu Y, Song S, Li J., J Huazhong Univ Sci Technolog Med Sci 28(5), 2008
PMID: 18846330
Increased tissue transglutaminase expression in human atherosclerotic coronary arteries.
Cho BR, Kim MK, Suh DH, Hahn JH, Lee BG, Choi YC, Kwon TJ, Kim SY, Kim DJ., Coron Artery Dis 19(7), 2008
PMID: 18923241
Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis.
Gareus R, Kotsaki E, Xanthoulea S, van der Made I, Gijbels MJ, Kardakaris R, Polykratis A, Kollias G, de Winther MP, Pasparakis M., Cell Metab 8(5), 2008
PMID: 19046569
Macrophage-specific inhibition of NF-kappaB activation reduces foam-cell formation.
Ferreira V, van Dijk KW, Groen AK, Vos RM, van der Kaa J, Gijbels MJ, Havekes LM, Pannekoek H., Atherosclerosis 192(2), 2007
PMID: 16938301
Ethanol beverages containing polyphenols decrease nuclear factor kappa-B activation in mononuclear cells and circulating MCP-1 concentrations in healthy volunteers during a fat-enriched diet.
Blanco-Colio LM, Muñoz-García B, Martín-Ventura JL, Alvarez-Sala LA, Castilla M, Bustamante A, Lamuela-Raventós RM, Gómez-Gerique J, Fernández-Cruz A, Millán J, Egido J., Atherosclerosis 192(2), 2007
PMID: 16970955
Ozonized low density lipoprotein (ozLDL) inhibits NF-kappaB and IRAK-1-associated signaling.
Cappello C, Saugel B, Huth KC, Zwergal A, Krautkrämer M, Furman C, Rouis M, Wieser B, Schneider HW, Neumeier D, Brand K., Arterioscler Thromb Vasc Biol 27(1), 2007
PMID: 17053167
Mulberry leaf aqueous fractions inhibit TNF-alpha-induced nuclear factor kappaB (NF-kappaB) activation and lectin-like oxidized LDL receptor-1 (LOX-1) expression in vascular endothelial cells.
Shibata Y, Kume N, Arai H, Hayashida K, Inui-Hayashida A, Minami M, Mukai E, Toyohara M, Harauma A, Murayama T, Kita T, Hara S, Kamei K, Yokode M., Atherosclerosis 193(1), 2007
PMID: 17055514
Protective effects of magnolol against oxidized LDL-induced apoptosis in endothelial cells.
Ou HC, Chou FP, Sheu WH, Hsu SL, Lee WJ., Arch Toxicol 81(6), 2007
PMID: 17216433
Influence of stress and nutrition on cattle immunity.
Carroll JA, Forsberg NE., Vet Clin North Am Food Anim Pract 23(1), 2007
PMID: 17382844
Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet.
Mehta JL, Sanada N, Hu CP, Chen J, Dandapat A, Sugawara F, Satoh H, Inoue K, Kawase Y, Jishage K, Suzuki H, Takeya M, Schnackenberg L, Beger R, Hermonat PL, Thomas M, Sawamura T., Circ Res 100(11), 2007
PMID: 17478727
Apolipoprotein E interrupts interleukin-1beta signaling in vascular smooth muscle cells.
Kawamura A, Baitsch D, Telgmann R, Feuerborn R, Weissen-Plenz G, Hagedorn C, Saku K, Brand-Herrmann SM, von Eckardstein A, Assmann G, Nofer JR., Arterioscler Thromb Vasc Biol 27(7), 2007
PMID: 17510469
Suppression of complement regulatory protein C1 inhibitor in vascular endothelial activation by inhibiting vascular cell adhesion molecule-1 action.
Zhang H, Qin G, Liang G, Li J, Chiu I, Barrington RA, Liu D., Biochem Biophys Res Commun 358(4), 2007
PMID: 17521609
Homocysteine induces VCAM-1 gene expression through NF-kappaB and NAD(P)H oxidase activation: protective role of Mediterranean diet polyphenolic antioxidants.
Carluccio MA, Ancora MA, Massaro M, Carluccio M, Scoditti E, Distante A, Storelli C, De Caterina R., Am J Physiol Heart Circ Physiol 293(4), 2007
PMID: 17586618
Nanoparticles-a thoracic toxicology perspective.
Duffin R, Mills NL, Donaldson K., Yonsei Med J 48(4), 2007
PMID: 17722227
Acetylbritannilactone suppresses lipopolysaccharide-induced vascular smooth muscle cell inflammatory response.
Liu YP, Wen JK, Zheng B, Zhang DQ, Han M., Eur J Pharmacol 577(1-3), 2007
PMID: 17915214
Nitric oxide and mitochondrial signaling: from physiology to pathophysiology.
Erusalimsky JD, Moncada S., Arterioscler Thromb Vasc Biol 27(12), 2007
PMID: 17885213
Increased expression of nuclear NF-kappaB after coronary artery balloon injury can be inhibited by intracoronary beta-irradiation.
Su CH, Hsieh BT, Leung SW, Wu CJ, Chiu SY, Lin CS., Int J Radiat Biol 83(10), 2007
PMID: 17729165
A nuclear factor-kappaB inhibitor pyrrolidine dithiocarbamate ameliorates pulmonary hypertension in rats.
Sawada H, Mitani Y, Maruyama J, Jiang BH, Ikeyama Y, Dida FA, Yamamoto H, Imanaka-Yoshida K, Shimpo H, Mizoguchi A, Maruyama K, Komada Y., Chest 132(4), 2007
PMID: 17934115
Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming.
Hastings NE, Simmers MB, McDonald OG, Wamhoff BR, Blackman BR., Am J Physiol Cell Physiol 293(6), 2007
PMID: 17913848
Vascular oxidant stress and inflammation in hyperhomocysteinemia.
Papatheodorou L, Weiss N., Antioxid Redox Signal 9(11), 2007
PMID: 17822365
Regulation of Src homology 2-containing protein tyrosine phosphatase by advanced glycation end products: the role on atherosclerosis in diabetes.
Seki N, Hashimoto N, Taira M, Yagi S, Yoshida Y, Ishikawa K, Suzuki Y, Sano H, Horiuchi S, Yoshida S, Sakurai K, Yagui K, Makino H, Saito Y., Metabolism 56(11), 2007
PMID: 17950112
Trace element status in Saudi patients with established atherosclerosis.
Alissa EM, Bahjri SM, Ahmed WH, Al-Ama N, Ferns GA., J Trace Elem Med Biol 20(2), 2006
PMID: 16785050
Metformin inhibits proinflammatory responses and nuclear factor-kappaB in human vascular wall cells.
Isoda K, Young JL, Zirlik A, MacFarlane LA, Tsuboi N, Gerdes N, Schönbeck U, Libby P., Arterioscler Thromb Vasc Biol 26(3), 2006
PMID: 16385087
Cytokine stimulation of pregnancy-associated plasma protein A expression in human coronary artery smooth muscle cells: inhibition by resveratrol.
Conover CA, Bale LK, Harrington SC, Resch ZT, Overgaard MT, Oxvig C., Am J Physiol Cell Physiol 290(1), 2006
PMID: 16338976
Endothelial cell heterogeneity and atherosclerosis.
Aird WC., Curr Atheroscler Rep 8(1), 2006
PMID: 16455017
Effects of simvastatin on NF-kappaB-DNA binding activity and monocyte chemoattractant protein-1 expression in a rabbit model of atherosclerosis.
Yang X, Wang L, Zeng H, Dubey L, Zhou N, Pu J., J Huazhong Univ Sci Technolog Med Sci 26(2), 2006
PMID: 16850745
Inhibition of the ubiquitin-proteasome system: a new avenue for atherosclerosis.
Tan C, Li Y, Tan X, Pan H, Huang W., Clin Chem Lab Med 44(10), 2006
PMID: 17032134
Toll-like receptor 4 polymorphism is associated with coronary stenosis but not with the occurrence of acute or old myocardial infarctions.
Hernesniemi J, Lehtimäki T, Rontu R, Islam MS, Eklund C, Mikkelsson J, Ilveskoski E, Kajander O, Goebeler S, Viiri LE, Hurme M, Karhunen PJ., Scand J Clin Lab Invest 66(8), 2006
PMID: 17101559
6A3-5/Osa2 is an early activated gene implicated in the control of vascular smooth muscle cell functions.
Garin G, Zibara K, Aguilar F, Lo M, Hurlstone A, Poston R, Mcgregor JL., J Biomed Biotechnol 2006(5), 2006
PMID: 17489020
TNFalpha induces ABCA1 through NF-kappaB in macrophages and in phagocytes ingesting apoptotic cells.
Gerbod-Giannone MC, Li Y, Holleboom A, Han S, Hsu LC, Tabas I, Tall AR., Proc Natl Acad Sci U S A 103(9), 2006
PMID: 16492740
The good fat hormone: adiponectin and cardiovascular disease.
Do D, Alvarez J, Chiquette E, Chilton R., Curr Atheroscler Rep 8(2), 2006
PMID: 16510042
Nuclear factor-kappaB p65 and upregulation of interleukin-6 in retinal ischemia/reperfusion injury in rats.
Wang J, Jiang S, Kwong JM, Sanchez RN, Sadun AA, Lam TT., Brain Res 1081(1), 2006
PMID: 16530172
Cytokines in atherosclerosis: pathogenic and regulatory pathways.
Tedgui A, Mallat Z., Physiol Rev 86(2), 2006
PMID: 16601268
[LDL: from metabolic syndrome to instability of the atherosclerotic plaque].
Siqueira AF, Abdalla DS, Ferreira SR., Arq Bras Endocrinol Metabol 50(2), 2006
PMID: 16767300
Transcription factor and kinase-mediated signaling in atherosclerosis and vascular injury.
Adhikari N, Charles N, Lehmann U, Hall JL., Curr Atheroscler Rep 8(3), 2006
PMID: 16640963
Parthenolide modulates the NF-kappaB-mediated inflammatory responses in experimental atherosclerosis.
López-Franco O, Hernández-Vargas P, Ortiz-Muñoz G, Sanjuán G, Suzuki Y, Ortega L, Blanco J, Egido J, Gómez-Guerrero C., Arterioscler Thromb Vasc Biol 26(8), 2006
PMID: 16741149
Inhibitory effects of NFkappaB decoy oligodeoxynucleotides on neointimal hyperplasia in a rabbit vein graft model.
Miyake T, Aoki M, Shiraya S, Tanemoto K, Ogihara T, Kaneda Y, Morishita R., J Mol Cell Cardiol 41(3), 2006
PMID: 16762361
Proteasome inhibition attenuates lung injury induced by intestinal ischemia reperfusion in rats.
Tian XF, Zhang XS, Li YH, Wang ZZ, Zhang F, Wang LM, Yao JH., Life Sci 79(22), 2006
PMID: 16875703
Cytochrome P450 epoxygenase CYP2J2 and the risk of coronary artery disease.
Spiecker M, Liao J., Trends Cardiovasc Med 16(6), 2006
PMID: 16839864
Glucose control with insulin results in reduction of NF-kappaB-binding activity in mononuclear blood cells of patients with recently manifested type 1 diabetes.
Schiekofer S, Galasso G, Andrassy M, Aprahamian T, Schneider J, Rocnik E., Diabetes Obes Metab 8(5), 2006
PMID: 16918581
Ursane triterpenoids inhibit atherosclerosis and xanthoma in LDL receptor knockout mice.
Zhang Q, Chang Z, Wang Q., Cardiovasc Drugs Ther 20(5), 2006
PMID: 17136324
Stent-based local delivery of nuclear factor-kappaB decoy attenuates in-stent restenosis in hypercholesterolemic rabbits.
Ohtani K, Egashira K, Nakano K, Zhao G, Funakoshi K, Ihara Y, Kimura S, Tominaga R, Morishita R, Sunagawa K., Circulation 114(25), 2006
PMID: 17130346
Induction of neutrophil gelatinase-associated lipocalin in vascular injury via activation of nuclear factor-kappaB.
Bu DX, Hemdahl AL, Gabrielsen A, Fuxe J, Zhu C, Eriksson P, Yan ZQ., Am J Pathol 169(6), 2006
PMID: 17148685
A selective NFkappaB inhibitor, DHMEQ, reduced atherosclerosis in ApoE-deficient mice.
Chiba T, Kondo Y, Shinozaki S, Kaneko E, Ishigami A, Maruyama N, Umezawa K, Shimokado K., J Atheroscler Thromb 13(6), 2006
PMID: 17192695
Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids.
Spiecker M, Liao JK., Arch Biochem Biophys 433(2), 2005
PMID: 15581597
The proteasome: a central regulator of inflammation and macrophage function.
Qureshi N, Vogel SN, Van Way C, Papasian CJ, Qureshi AA, Morrison DC., Immunol Res 31(3), 2005
PMID: 15888915
Distinct NF-kappaB regulation by shear stress through Ras-dependent IkappaBalpha oscillations: real-time analysis of flow-mediated activation in live cells.
Ganguli A, Persson L, Palmer IR, Evans I, Yang L, Smallwood R, Black R, Qwarnstrom EE., Circ Res 96(6), 2005
PMID: 15731464
Nuclear factor kappaB signaling in atherogenesis.
de Winther MP, Kanters E, Kraal G, Hofker MH., Arterioscler Thromb Vasc Biol 25(5), 2005
PMID: 15731497
Liver X receptor agonists inhibit tissue factor expression in macrophages.
Terasaka N, Hiroshima A, Ariga A, Honzumi S, Koieyama T, Inaba T, Fujiwara T., FEBS J 272(6), 2005
PMID: 15752369
Roxithromycin is an inhibitor of human coronary artery smooth muscle cells proliferation: a potential ability to prevent coronary heart disease.
Tomita H, Osanai T, Toki T, Maeda N, Murakami R, Chen Z, Yamabe H, Osawa H, Yasujima M, Okumura K., Atherosclerosis 182(1), 2005
PMID: 16115478
The subendothelial extracellular matrix modulates NF-kappaB activation by flow: a potential role in atherosclerosis.
Orr AW, Sanders JM, Bevard M, Coleman E, Sarembock IJ, Schwartz MA., J Cell Biol 169(1), 2005
PMID: 15809308
Regulation of vascular smooth muscle cell proliferation: role of NF-kappaB revisited.
Mehrhof FB, Schmidt-Ullrich R, Dietz R, Scheidereit C., Circ Res 96(9), 2005
PMID: 15831813
Local administration of NF-kappa B decoy oligonucleotides to prevent restenosis after balloon angioplasty: an experimental study in New Zealand white rabbits.
Kalinowski M, Viehofer K, Hamann C, Barry JJ, Kleb B, Klose KJ, Wagner HJ, Alfke H., Cardiovasc Intervent Radiol 28(3), 2005
PMID: 15886949
Expression of activated transcription factor nuclear factor-kappaB in periodontally diseased tissues.
Ambili R, Santhi WS, Janam P, Nandakumar K, Pillai MR., J Periodontol 76(7), 2005
PMID: 16018758
Tendon xanthomas in familial hypercholesterolemia are associated with a differential inflammatory response of macrophages to oxidized LDL.
Artieda M, Cenarro A, Junquera C, Lasierra P, Martínez-Lorenzo MJ, Pocoví M, Civeira F., FEBS Lett 579(20), 2005
PMID: 16083882
12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB.
Bolick DT, Orr AW, Whetzel A, Srinivasan S, Hatley ME, Schwartz MA, Hedrick CC., Arterioscler Thromb Vasc Biol 25(11), 2005
PMID: 16166569
Nuclear factor kappa B signaling in macrophage function and atherogenesis.
Xanthoulea S, Curfs DM, Hofker MH, de Winther MP., Curr Opin Lipidol 16(5), 2005
PMID: 16148538
Involvement of c-Jun NH2 terminal kinase and p38MAPK in rapamycin-mediated inhibition of neointimal formation in rat carotid arteries.
Omura T, Yoshiyama M, Izumi Y, Kim S, Matsumoto R, Enomoto S, Kusuyama T, Nishiya D, Nakamura Y, Akioka K, Iwao H, Takeuchi K, Yoshikawa J., J Cardiovasc Pharmacol 46(4), 2005
PMID: 16160607
Anti-inflammatory effects of polyunsaturated fatty acids in THP-1 cells.
Zhao G, Etherton TD, Martin KR, Vanden Heuvel JP, Gillies PJ, West SG, Kris-Etherton PM., Biochem Biophys Res Commun 336(3), 2005
PMID: 16169525
Relationship between reduced BCL-2 expression in circulating mononuclear cells and early nephropathy in type 1 diabetes.
Cipollone F, Chiarelli F, Iezzi A, Fazia ML, Cuccurullo C, Pini B, De Cesare D, Torello M, Tumini S, Cuccurullo F, Mezzetti A., Int J Immunopathol Pharmacol 18(4), 2005
PMID: 16388709
Helper T cells and atherosclerosis: the cytokine web.
Baidya SG, Zeng QT., Postgrad Med J 81(962), 2005
PMID: 16344296
Hyperhomocysteinemia activates nuclear factor-kappaB in endothelial cells via oxidative stress.
Au-Yeung KK, Woo CW, Sung FL, Yip JC, Siow YL, O K., Circ Res 94(1), 2004
PMID: 14630727
RORalpha1 and RORalpha4 suppress TNF-alpha-induced VCAM-1 and ICAM-1 expression in human endothelial cells.
Migita H, Satozawa N, Lin JH, Morser J, Kawai K., FEBS Lett 557(1-3), 2004
PMID: 14741380
Reduced beta3-endonexin levels are associated with enhanced urokinase-type plasminogen activator receptor expression in ApoE-/- mice.
Besta F, Müller I, Lorenz M, Massberg S, Bültmann A, Cabeza N, Richter T, Kremmer E, Nothdurfter C, Brand K, Gawaz M., Thromb Res 114(4), 2004
PMID: 15381392
Statins in hypertensive patients: potential explanations for the ASCOT-LLA study results.
Blanco-Colio LM, Osende JI, Martín-Ventura JL, Tuñón J, Egido J., Drugs 64 Suppl 2(), 2004
PMID: 15765891
Angiopoietin 2 induces cell cycle arrest in endothelial cells: a possible mechanism involved in advanced plaque neovascularization.
Calvi C, Dentelli P, Pagano M, Rosso A, Pegoraro M, Giunti S, Garbarino G, Camussi G, Pegoraro L, Brizzi MF., Arterioscler Thromb Vasc Biol 24(3), 2004
PMID: 14726409
NF-kappaB activation and Fas ligand overexpression in blood and plaques of patients with carotid atherosclerosis: potential implication in plaque instability.
Martín-Ventura JL, Blanco-Colio LM, Muñoz-García B, Gómez-Hernández A, Arribas A, Ortega L, Tuñón J, Egido J., Stroke 35(2), 2004
PMID: 14739407
Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta.
Passerini AG, Polacek DC, Shi C, Francesco NM, Manduchi E, Grant GR, Pritchard WF, Powell S, Chang GY, Stoeckert CJ, Davies PF., Proc Natl Acad Sci U S A 101(8), 2004
PMID: 14983035
Rev-erbalpha upregulates NF-kappaB-responsive genes in vascular smooth muscle cells.
Migita H, Morser J, Kawai K., FEBS Lett 561(1-3), 2004
PMID: 15013753
Strategy for Prevention of Restenosis after PTA. Clinical and Basic Approaches.
Yoshimura S, Kaku Y, Kokuzawa J, Hayashi K, Sakai N., Interv Neuroradiol 10 Suppl 1(), 2004
PMID: 20587274
Beyond the endothelium: NF-kappaB regulation of smooth muscle function.
Raines EW, Garton KJ, Ferri N., Circ Res 94(6), 2004
PMID: 15059939
Acetylsalicylic acid inhibits monocyte adhesion to endothelial cells by an antioxidative mechanism.
Eisele G, Schwedhelm E, Schieffer B, Tsikas D, Böger RH., J Cardiovasc Pharmacol 43(4), 2004
PMID: 15085062
Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis.
Monaco C, Andreakos E, Kiriakidis S, Mauri C, Bicknell C, Foxwell B, Cheshire N, Paleolog E, Feldmann M., Proc Natl Acad Sci U S A 101(15), 2004
PMID: 15064395
Balance between PGD synthase and PGE synthase is a major determinant of atherosclerotic plaque instability in humans.
Cipollone F, Fazia M, Iezzi A, Ciabattoni G, Pini B, Cuccurullo C, Ucchino S, Spigonardo F, De Luca M, Prontera C, Chiarelli F, Cuccurullo F, Mezzetti A., Arterioscler Thromb Vasc Biol 24(7), 2004
PMID: 15155382
In vitro study of the potential role of guanidines in leukocyte functions related to atherogenesis and infection.
Glorieux GL, Dhondt AW, Jacobs P, Van Langeraert J, Lameire NH, De Deyn PP, Vanholder RC., Kidney Int 65(6), 2004
PMID: 15149331
Cardiovascular effects of milk enriched with omega-3 polyunsaturated fatty acids, oleic acid, folic acid, and vitamins E and B6 in volunteers with mild hyperlipidemia.
Carrero JJ, Baró L, Fonollá J, González-Santiago M, Martínez-Férez A, Castillo R, Jiménez J, Boza JJ, López-Huertas E., Nutrition 20(6), 2004
PMID: 15165614
Dual role of oxidized LDL on the NF-kappaB signaling pathway.
Robbesyn F, Salvayre R, Negre-Salvayre A., Free Radic Res 38(6), 2004
PMID: 15346645
Wine polyphenols and promotion of cardiac health.
Cooper KA, Chopra M, Thurnham DI., Nutrition research reviews. 17(1), 2004
PMID: IND43648761
Nuclear factor-kappaB: its role in health and disease.
Kumar A, Takada Y, Boriek AM, Aggarwal BB., J Mol Med (Berl) 82(7), 2004
PMID: 15175863
Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice.
Zhou J, Werstuck GH, Lhoták S, de Koning AB, Sood SK, Hossain GS, Møller J, Ritskes-Hoitinga M, Falk E, Dayal S, Lentz SR, Austin RC., Circulation 110(2), 2004
PMID: 15210586
More fibrosis and thrombotic complications but similar expression patterns of markers for coagulation and inflammation in symptomatic plaques from DM2 patients.
Sommeijer DW, Beganovic A, Schalkwijk CG, Ploegmakers H, van der Loos CM, van Aken BE, ten Cate H, van der Wal AC., J Histochem Cytochem 52(9), 2004
PMID: 15314081
MAPK-dependent regulation of IL-1- and beta-adrenoreceptor-induced inflammatory cytokine production from mast cells: implications for the stress response.
Chi DS, Fitzgerald SM, Pitts S, Cantor K, King E, Lee SA, Huang SK, Krishnaswamy G., BMC Immunol 5(), 2004
PMID: 15383152
Role of oxidative modifications in atherosclerosis.
Stocker R, Keaney JF., Physiol Rev 84(4), 2004
PMID: 15383655
Interleukin-10 attenuates the response to vascular injury.
Zimmerman MA, Reznikov LL, Raeburn CD, Selzman CH., J Surg Res 121(2), 2004
PMID: 15501460
Butter and walnuts, but not olive oil, elicit postprandial activation of nuclear transcription factor kappaB in peripheral blood mononuclear cells from healthy men.
Bellido C, López-Miranda J, Blanco-Colio LM, Pérez-Martínez P, Muriana FJ, Martín-Ventura JL, Marín C, Gómez P, Fuentes F, Egido J, Pérez-Jiménez F., Am J Clin Nutr 80(6), 2004
PMID: 15585759
Anti-inflammatory and immunomodulatory effects of statins.
Blanco-Colio LM, Tuñón J, Martín-Ventura JL, Egido J., Kidney Int 63(1), 2003
PMID: 12472764
Patterns of oxidized epitopes, but not NF-kappa B expression, change during atherogenesis in WHHL rabbits.
Bräsen JH, Häkkinen T, Malle E, Beisiegel U, Ylä-Herttuala S., Atherosclerosis 166(1), 2003
PMID: 12482546
HMG-CoA reductase inhibitors regulate inflammatory transcription factors in human endothelial and vascular smooth muscle cells.
Dichtl W, Dulak J, Frick M, Alber HF, Schwarzacher SP, Ares MP, Nilsson J, Pachinger O, Weidinger F., Arterioscler Thromb Vasc Biol 23(1), 2003
PMID: 12524225
Effect of the proteasome inhibitor MLN519 on the expression of inflammatory molecules following middle cerebral artery occlusion and reperfusion in the rat.
Berti R, Williams AJ, Velarde LC, Moffett JR, Elliott PJ, Adams J, Yao C, Dave JR, Tortella FC., Neurotox Res 5(7), 2003
PMID: 14715434
Inhibition of NFkappaB activation using cis-element 'decoy' of NFkappaB binding site reduces neointimal formation in porcine balloon-injured coronary artery model.
Yamasaki K, Asai T, Shimizu M, Aoki M, Hashiya N, Sakonjo H, Makino H, Kaneda Y, Ogihara T, Morishita R., Gene Ther 10(4), 2003
PMID: 12595894
Light-induced photoreceptor degeneration may involve the NF kappa B/caspase-1 pathway in vivo.
Wu T, Chiang SK, Chau FY, Tso MO., Brain Res 967(1-2), 2003
PMID: 12650962
Redox regulation following cardiac ischemia and reperfusion.
Marczin N, Bundy RE, Hoare GS, Yacoub M., Coron Artery Dis 14(2), 2003
PMID: 12655276
Transcriptional inhibition of interleukin-8 expression in tumor necrosis factor-tolerant cells: evidence for involvement of C/EBP beta.
Weber M, Sydlik C, Quirling M, Nothdurfter C, Zwergal A, Heiss P, Bell S, Neumeier D, Ziegler-Heitbrock HW, Brand K., J Biol Chem 278(26), 2003
PMID: 12707271
Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans.
Bruun JM, Lihn AS, Verdich C, Pedersen SB, Toubro S, Astrup A, Richelsen B., Am J Physiol Endocrinol Metab 285(3), 2003
PMID: 12736161
Activated platelets trigger an inflammatory response and enhance migration of aortic smooth muscle cells.
Massberg S, Vogt F, Dickfeld T, Brand K, Page S, Gawaz M., Thromb Res 110(4), 2003
PMID: 14512080
Engineering the response to vascular injury: divergent effects of deregulated E2F1 expression on vascular smooth muscle cells and endothelial cells result in endothelial recovery and inhibition of neointimal growth.
Goukassian DA, Kishore R, Krasinski K, Dolan C, Luedemann C, Yoon YS, Kearney M, Hanley A, Ma H, Asahara T, Isner JM, Losordo DW., Circ Res 93(2), 2003
PMID: 12829616
Garlic (Allium sativum L.) modulates cytokine expression in lipopolysaccharide-activated human blood thereby inhibiting NF-kappaB activity.
Keiss HP, Dirsch VM, Hartung T, Haffner T, Trueman L, Auger J, Kahane R, Vollmar AM., J Nutr 133(7), 2003
PMID: 12840173
Hematein inhibits atherosclerosis by inhibition of reactive oxygen generation and NF-kappaB-dependent inflammatory mediators in hyperlipidemic mice.
Choi JH, Jeong TS, Kim DY, Kim YM, Na HJ, Nam KH, Lee SB, Kim HC, Oh SR, Choi YK, Bok SH, Oh GT., J Cardiovasc Pharmacol 42(2), 2003
PMID: 12883334
The receptor RAGE as a progression factor amplifying arachidonate-dependent inflammatory and proteolytic response in human atherosclerotic plaques: role of glycemic control.
Cipollone F, Iezzi A, Fazia M, Zucchelli M, Pini B, Cuccurullo C, De Cesare D, De Blasis G, Muraro R, Bei R, Chiarelli F, Schmidt AM, Cuccurullo F, Mezzetti A., Circulation 108(9), 2003
PMID: 12912808
Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.
Kanters E, Pasparakis M, Gijbels MJ, Vergouwe MN, Partouns-Hendriks I, Fijneman RJ, Clausen BE, Förster I, Kockx MM, Rajewsky K, Kraal G, Hofker MH, de Winther MP., J Clin Invest 112(8), 2003
PMID: 14561702
[Role of coronary risk factors in blood thrombogenicity and acute coronary syndromes].
Sambola A, Fuster V, Badimon JJ., Rev Esp Cardiol 56(10), 2003
PMID: 14563295
Clinical implications of matrix metalloproteinases.
Mandal M, Mandal A, Das S, Chakraborti T, Sajal C., Mol Cell Biochem 252(1-2), 2003
PMID: 14577606
Celiprolol activates eNOS through the PI3K-Akt pathway and inhibits VCAM-1 Via NF-kappaB induced by oxidative stress.
Kobayashi N, Mita S, Yoshida K, Honda T, Kobayashi T, Hara K, Nakano S, Tsubokou Y, Matsuoka H., Hypertension 42(5), 2003
PMID: 14557279
Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.
Ameziane N, Beillat T, Verpillat P, Chollet-Martin S, Aumont MC, Seknadji P, Lamotte M, Lebret D, Ollivier V, de Prost D., Arterioscler Thromb Vasc Biol 23(12), 2003
PMID: 14563652
Mechanisms involved in the stimulatory effect of advanced glycation end products on growth of rat aortic smooth muscle cells.
Seki N, Hashimoto N, Sano H, Horiuchi S, Yagui K, Makino H, Saito Y., Metabolism 52(12), 2003
PMID: 14669155
C-reactive protein activates the nuclear factor-kappaB signal transduction pathway in saphenous vein endothelial cells: implications for atherosclerosis and restenosis.
Verma S, Badiwala MV, Weisel RD, Li SH, Wang CH, Fedak PW, Li RK, Mickle DA., J Thorac Cardiovasc Surg 126(6), 2003
PMID: 14688701
The role of estrogen in cardiovascular disease.
Baker L, Meldrum KK, Wang M, Sankula R, Vanam R, Raiesdana A, Tsai B, Hile K, Brown JW, Meldrum DR., J Surg Res 115(2), 2003
PMID: 14697301
Unsaturated fatty acids selectively induce an inflammatory environment in human endothelial cells.
Toborek M, Lee YW, Garrido R, Kaiser S, Hennig B., Am J Clin Nutr 75(1), 2002
PMID: 11756069
Nuclear factor-kappaB immunoreactivity is present in human coronary plaque and enhanced in patients with unstable angina pectoris.
Wilson SH, Best PJ, Edwards WD, Holmes DR, Carlson PJ, Celermajer DS, Lerman A., Atherosclerosis 160(1), 2002
PMID: 11755932
Mechanical stress-induced apoptosis in the cardiovascular system.
Wernig F, Xu Q., Prog Biophys Mol Biol 78(2-3), 2002
PMID: 12429110
The role of oxidative stress in mechanisms of metal-induced carcinogenesis.
Galaris D, Evangelou A., Crit Rev Oncol Hematol 42(1), 2002
PMID: 11923071
Phytochemical inhibition of interleukin-4-activated Stat6 and expression of VCAM-1.
Schnyder B, Schnyder-Candrian S, Panski A, Bömmel H, Heim M, Duschl A, Moser R., Biochem Biophys Res Commun 292(4), 2002
PMID: 11944890
Effect of alcohol on lipids and lipoproteins in relation to atherosclerosis.
Hannuksela ML, Liisanantti MK, Savolainen MJ., Crit Rev Clin Lab Sci 39(3), 2002
PMID: 12120782
[Interleukin-10 and coronary disease].
Pérez Fernández R, Kaski JC., Rev Esp Cardiol 55(7), 2002
PMID: 12113702
Lack of TNF-alpha attenuates intimal hyperplasia after mouse carotid artery injury.
Zimmerman MA, Selzman CH, Reznikov LL, Miller SA, Raeburn CD, Emmick J, Meng X, Harken AH., Am J Physiol Regul Integr Comp Physiol 283(2), 2002
PMID: 12121864
Induction of IkappaB: atrial natriuretic peptide as a regulator of the NF-kappaB pathway.
Kiemer AK, Weber NC, Vollmar AM., Biochem Biophys Res Commun 295(5), 2002
PMID: 12135603
Vascular inflammation and the renin-angiotensin system.
Brasier AR, Recinos A, Eledrisi MS., Arterioscler Thromb Vasc Biol 22(8), 2002
PMID: 12171785
Quantitative real-time RT-PCR analysis of inflammatory gene expression associated with ischemia-reperfusion brain injury.
Berti R, Williams AJ, Moffett JR, Hale SL, Velarde LC, Elliott PJ, Yao C, Dave JR, Tortella FC., J Cereb Blood Flow Metab 22(9), 2002
PMID: 12218412
Increased IkappaB kinase activity is associated with activated NF-kappaB in acute myeloid blasts.
Baumgartner B, Weber M, Quirling M, Fischer C, Page S, Adam M, Von Schilling C, Waterhouse C, Schmid C, Neumeier D, Brand K., Leukemia 16(10), 2002
PMID: 12357358
A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation.
Massberg S, Brand K, Grüner S, Page S, Müller E, Müller I, Bergmeier W, Richter T, Lorenz M, Konrad I, Nieswandt B, Gawaz M., J Exp Med 196(7), 2002
PMID: 12370251
Chlamydia pneumoniae activates IKK/I kappa B-mediated signaling, which is inhibited by 4-HNE and following primary exposure.
Donath B, Fischer C, Page S, Prebeck S, Jilg N, Weber M, da Costa C, Neumeier D, Miethke T, Brand K., Atherosclerosis 165(1), 2002
PMID: 12208473
Molecular inflammation hypothesis of aging based on the anti-aging mechanism of calorie restriction.
Chung HY, Kim HJ, Kim KW, Choi JS, Yu BP., Microsc Res Tech 59(4), 2002
PMID: 12424787
Regulation of cell signalling by vitamin E.
Rimbach G, Minihane AM, Majewicz J, Fischer A, Pallauf J, Virgli F, Weinberg PD., Proc Nutr Soc 61(4), 2002
PMID: 12691170
Activation of tubular epithelial cells in diabetic nephropathy.
Morcos M, Sayed AA, Bierhaus A, Yard B, Waldherr R, Merz W, Kloeting I, Schleicher E, Mentz S, Abd el Baki RF, Tritschler H, Kasper M, Schwenger V, Hamann A, Dugi KA, Schmidt AM, Stern D, Ziegler R, Haering HU, Andrassy M, van der Woude F, Nawroth PP., Diabetes 51(12), 2002
PMID: 12453911
Suppression of cyclooxygenase-2 and inducible nitric oxide synthase expression by conjugated linoleic acid in murine macrophages.
Iwakiri Y, Sampson DA, Allen KG., Prostaglandins Leukot Essent Fatty Acids 67(6), 2002
PMID: 12468265
Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression.
Tzima E, Del Pozo MA, Kiosses WB, Mohamed SA, Li S, Chien S, Schwartz MA., EMBO J 21(24), 2002
PMID: 12486000
The smooth muscle cell membrane during atherogenesis: a potential target for amlodipine in atheroprotection.
Tulenko TN, Sumner AE, Chen M, Huang Y, Laury-Kleintop L, Ferdinand FD., Am Heart J 141(2 suppl), 2001
PMID: 11174352
Homocysteine inhibits TNF-alpha-induced endothelial adhesion molecule expression and monocyte adhesion via nuclear factor-kappaB dependent pathway.
Stangl V, Günther C, Jarrin A, Bramlage P, Moobed M, Staudt A, Baumann G, Stangl K, Felix SB., Biochem Biophys Res Commun 280(4), 2001
PMID: 11162639
NF-kappaB: pivotal mediator or innocent bystander in atherogenesis?
Collins T, Cybulsky MI., J Clin Invest 107(3), 2001
PMID: 11160146
The effect of alpha-tocopherol on monocyte proatherogenic activity.
Jialal I, Devaraj S, Kaul N., J Nutr 131(2), 2001
PMID: 11160567
Transcription factor-kappa B (NF-kappa B) and renal disease.
Guijarro C, Egido J., Kidney Int 59(2), 2001
PMID: 11168923
[Cellular and molecular biology of atherosclerotic lesions]
Martínez-González J, Llorente-Cortés V, Badimon L., Rev Esp Cardiol 54(2), 2001
PMID: 11181311
Peroxisome proliferator-activated receptors in atherosclerosis and inflammation--an update.
Elangbam CS, Tyler RD, Lightfoot RM., Toxicol Pathol 29(2), 2001
PMID: 11421489
Inhibition of cytokine-induced vascular cell adhesion molecule-1 expression; possible mechanism for anti-atherogenic effect of Agastache rugosa.
Hong JJ, Choi JH, Oh SR, Lee HK, Park JH, Lee KY, Kim JJ, Jeong TS, Oh GT., FEBS Lett 495(3), 2001
PMID: 11334881
High-energy diets, fatty acids and endothelial cell function: implications for atherosclerosis.
Hennig B, Toborek M, McClain CJ., J Am Coll Nutr 20(2 suppl), 2001
PMID: 11349944
The role of apoptotic cell death in cardiovascular disease.
McLaughlin R, Kelly CJ, Kay E, Bouchier-Hayes D., Ir J Med Sci 170(2), 2001
PMID: 11491050
Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors.
Ruiz-Ortega M, Ruiz-Ortega M, Lorenzo O, Rupérez M, Blanco J, Egido J., Am J Pathol 158(5), 2001
PMID: 11337372
Oxidized LDL-mediated monocyte adhesion to endothelial cells does not involve NFkappaB.
Dwivedi A, Anggård EE, Carrier MJ., Biochem Biophys Res Commun 284(1), 2001
PMID: 11374896
Cryptosporidium parvum activates nuclear factor kappaB in biliary epithelia preventing epithelial cell apoptosis.
Chen XM, Levine SA, Splinter PL, Tietz PS, Ganong AL, Jobin C, Gores GJ, Paya CV, LaRusso NF., Gastroenterology 120(7), 2001
PMID: 11375958
Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice.
Kislinger T, Tanji N, Wendt T, Qu W, Lu Y, Ferran LJ, Taguchi A, Olson K, Bucciarelli L, Goova M, Hofmann MA, Cataldegirmen G, D'Agati V, Pischetsrieder M, Stern DM, Schmidt AM., Arterioscler Thromb Vasc Biol 21(6), 2001
PMID: 11397695
Therapeutic implications of inflammation in atherosclerotic cardiovascular disease.
Selzman CH, Miller SA, Harken AH., Ann Thorac Surg 71(6), 2001
PMID: 11426810
Effects of conjugated linoleic acids and docosahexaenoic acid on rat liver and reproductive tissue fatty acids, prostaglandins and matrix metalloproteinase production.
Harris MA, Hansen RA, Vidsudhiphan P, Koslo JL, Thomas JB, Watkins BA, Allen KG., Prostaglandins Leukot Essent Fatty Acids 65(1), 2001
PMID: 11487304
Nuclear factor kappa-B and the heart.
Valen G, Yan ZQ, Hansson GK., J Am Coll Cardiol 38(2), 2001
PMID: 11499717
25-hydroxycholesterol induces lipopolysaccharide-tolerance and decreases a lipopolysaccharide-induced TNF-alpha secretion in macrophages.
Englund MC, Karlsson AL, Wiklund O, Bondjers G, Ohlsson BG., Atherosclerosis 158(1), 2001
PMID: 11500175
The effect of endothelin-1 on nuclear factor kappa B in macrophages.
Wilson SH, Simari RD, Lerman A., Biochem Biophys Res Commun 286(5), 2001
PMID: 11527395
Serum neopterin and activity of coronary artery disease.
Auer J, Berent R, Labetanig E, Eber B., Heart Dis 3(5), 2001
PMID: 11975809
Reciprocal antagonism between estrogen receptor and NF-kappaB activity in vivo.
Evans MJ, Eckert A, Lai K, Adelman SJ, Harnish DC., Circ Res 89(9), 2001
PMID: 11679413
Molecular aspects of lipoic acid in the prevention of diabetes complications.
Packer L, Kraemer K, Rimbach G., Nutrition 17(10), 2001
PMID: 11684397
Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB.
Bierhaus A, Schiekofer S, Schwaninger M, Andrassy M, Humpert PM, Chen J, Hong M, Luther T, Henle T, Klöting I, Morcos M, Hofmann M, Tritschler H, Weigle B, Kasper M, Smith M, Perry G, Schmidt AM, Stern DM, Häring HU, Schleicher E, Nawroth PP., Diabetes 50(12), 2001
PMID: 11723063
Cholesterol enrichment upregulates intercellular adhesion molecule-1 in human vascular endothelial cells.
Yuan Y, Verna LK, Wang NP, Liao HL, Ma KS, Wang Y, Zhu Y, Stemerman MB., Biochim Biophys Acta 1534(2-3), 2001
PMID: 11786300
Role of nuclear factor-kappa B (NF-kappa B) in inflammation, periodontitis, and atherogenesis.
Nichols TC, Fischer TH, Deliargyris EN, Baldwin AS., Ann Periodontol 6(1), 2001
PMID: 11887466
Activated nuclear factor-kappaB is present in the coronary vasculature in experimental hypercholesterolemia.
Wilson SH, Caplice NM, Simari RD, Holmes DR, Carlson PJ, Lerman A., Atherosclerosis 148(1), 2000
PMID: 10580167
Platelets induce alterations of chemotactic and adhesive properties of endothelial cells mediated through an interleukin-1-dependent mechanism. Implications for atherogenesis.
Gawaz M, Brand K, Dickfeld T, Pogatsa-Murray G, Page S, Bogner C, Koch W, Schömig A, Neumann F., Atherosclerosis 148(1), 2000
PMID: 10580173
NF-kappaB inhibition ameliorates angiotensin II-induced inflammatory damage in rats.
Muller DN, Dechend R, Mervaala EM, Park JK, Schmidt F, Fiebeler A, Theuer J, Breu V, Ganten D, Haller H, Luft FC., Hypertension 35(1 pt 2), 2000
PMID: 10642297
Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes.
Mervaala E, Müller DN, Park JK, Dechend R, Schmidt F, Fiebeler A, Bieringer M, Breu V, Ganten D, Haller H, Luft FC., Hypertension 35(1 pt 2), 2000
PMID: 10642325
The endothelium in atherogenesis.
Hunt BJ., Lupus 9(3), 2000
PMID: 10805486
Angiotensin-converting enzyme inhibitors downregulate tissue factor synthesis in monocytes.
Napoleone E, Di Santo A, Camera M, Tremoli E, Lorenzet R., Circ Res 86(2), 2000
PMID: 10666408
Adhesion of monocyte very late antigen-4 to endothelial vascular cell adhesion molecule-1 induces interleukin-1beta-dependent expression of interleukin-6 in endothelial cells.
Zohlnhöfer D, Brand K, Schipek K, Pogatsa-Murray G, Schömig A, Neumann FJ., Arterioscler Thromb Vasc Biol 20(2), 2000
PMID: 10669630
Increased serum neopterin: a marker of coronary artery disease activity in women.
Garcia-Moll X, Cole D, Zouridakis E, Kaski JC., Heart 83(3), 2000
PMID: 10677418
Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress.
Pueyo ME, Gonzalez W, Nicoletti A, Savoie F, Arnal JF, Michel JB., Arterioscler Thromb Vasc Biol 20(3), 2000
PMID: 10712386
Nuclear factor-kappa B activity and intestinal inflammation in dextran sulphate sodium (DSS)-induced colitis in mice is suppressed by gliotoxin.
Herfarth H, Brand K, Rath HC, Rogler G, Schölmerich J, Falk W., Clin Exp Immunol 120(1), 2000
PMID: 10759764
Induction of signal transduction pathways in rat gastric epithelial cells stimulated with interleukin-1beta.
Tominaga K, Higuchi K, Tsuno M, Watanabe T, Fujiwara Y, Kim S, Arakawa T, Iwao H, Kuroki T., Aliment Pharmacol Ther 14 Suppl 1(), 2000
PMID: 10807411
Macrophages stimulated with IFN-gamma activate NF-kappa B and induce MCP-1 gene expression in primary human endothelial cells.
Rimbach G, Valacchi G, Canali R, Virgili F., Mol Cell Biol Res Commun 3(4), 2000
PMID: 10891398
Essential roles of IkappaB kinases alpha and beta in serum- and IL-1-induced human VSMC proliferation.
Sasu S, Beasley D., Am J Physiol Heart Circ Physiol 278(6), 2000
PMID: 10843878
Pathogenesis of liver fibrosis: role of oxidative stress.
Poli G., Mol Aspects Med 21(3), 2000
PMID: 10978499
Antiphospholipid antibodies and the endothelium.
Hunt BJ, Khamashta MA., Curr Rheumatol Rep 2(3), 2000
PMID: 11123067
The carboxyl-terminal fragment of alpha1-antitrypsin is present in atherosclerotic plaques and regulates inflammatory transcription factors in primary human monocytes.
Dichtl W, Moraga F, Ares MP, Crisby M, Nilsson J, Lindgren S, Janciauskiene S., Mol Cell Biol Res Commun 4(1), 2000
PMID: 11152628
The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation.
Hajra L, Evans AI, Chen M, Hyduk SJ, Collins T, Cybulsky MI., Proc Natl Acad Sci U S A 97(16), 2000
PMID: 10922059
Red wine intake prevents nuclear factor-kappaB activation in peripheral blood mononuclear cells of healthy volunteers during postprandial lipemia.
Blanco-Colio LM, Valderrama M, Alvarez-Sala LA, Bustos C, Ortego M, Hernández-Presa MA, Cancelas P, Gómez-Gerique J, Millán J, Egido J., Circulation 102(9), 2000
PMID: 10961967
Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway.
Ouchi N, Kihara S, Arita Y, Okamoto Y, Maeda K, Kuriyama H, Hotta K, Nishida M, Takahashi M, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Funahashi T, Matsuzawa Y., Circulation 102(11), 2000
PMID: 10982546
Overexpression of truncated IkappaBalpha induces TNF-alpha-dependent apoptosis in human vascular smooth muscle cells.
Obara H, Takayanagi A, Hirahashi J, Tanaka K, Wakabayashi G, Matsumoto K, Shimazu M, Shimizu N, Kitajima M., Arterioscler Thromb Vasc Biol 20(10), 2000
PMID: 11031204
Implication of NF-kappaB in Helicobacter pylori-associated gastritis.
Isomoto H, Mizuta Y, Miyazaki M, Takeshima F, Omagari K, Murase K, Nishiyama T, Inoue K, Murata I, Kohno S., Am J Gastroenterol 95(10), 2000
PMID: 11051346
Serotonin increases interleukin-6 synthesis in human vascular smooth muscle cells.
Ito T, Ikeda U, Shimpo M, Yamamoto K, Shimada K., Circulation 102(20), 2000
PMID: 11076827
NF-kappaB activation in response to toxical and therapeutical agents: role in inflammation and cancer treatment.
Bours V, Bonizzi G, Bentires-Alj M, Bureau F, Piette J, Lekeux P, Merville M., Toxicology 153(1-3), 2000
PMID: 11090945
Pravastatin down-regulates inflammatory mediators in human monocytes in vitro.
Grip O, Janciauskiene S, Lindgren S., Eur J Pharmacol 410(1), 2000
PMID: 11134659
A role for reduced coenzyme Q in atherosclerosis?
Thomas SR, Witting PK, Stocker R., Biofactors 9(2-4), 1999
PMID: 10416033
Adenovirus-mediated gene transfer is augmented in basilar and carotid arteries of heritable hyperlipidemic rabbits.
Lund DD, Faraci FM, Ooboshi H, Davidson BL, Heistad DD., Stroke 30(1), 1999
PMID: 9880399
Mildly oxidized low-density lipoproteins decrease early production of interleukin 2 and nuclear factor kappaB binding to DNA in activated T-lymphocytes.
Caspar-Bauguil S, Tkaczuk J, Haure MJ, Durand M, Alcouffe J, Thomsen M, Salvayre R, Benoist H., Biochem J 337 ( Pt 2)(), 1999
PMID: 9882624
Serial analysis of gene expression to assess the endothelial cell response to an atherogenic stimulus.
de Waard V, van den Berg BM, Veken J, Schultz-Heienbrok R, Pannekoek H, van Zonneveld AJ., Gene 226(1), 1999
PMID: 9889296
A novel function for A20 in smooth muscle cells: inhibition of activation and proliferation.
Arvelo MB, Badrichani AZ, Stroka DM, Grey ST, Bach FH, Ferran C., Transplant Proc 31(1-2), 1999
PMID: 10083374
Very low-density lipoprotein activates nuclear factor-kappaB in endothelial cells.
Dichtl W, Nilsson L, Goncalves I, Ares MP, Banfi C, Calara F, Hamsten A, Eriksson P, Nilsson J., Circ Res 84(9), 1999
PMID: 10325246
The NFkappaB inhibitory peptide, IkappaBalpha, prevents human vascular smooth muscle proliferation.
Selzman CH, Shames BD, McIntyre RC, Banerjee A, Harken AH., Ann Thorac Surg 67(5), 1999
PMID: 10355388
Gallates inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of leukocyte adhesion molecules in vascular endothelial cells.
Murase T, Kume N, Hase T, Shibuya Y, Nishizawa Y, Tokimitsu I, Kita T., Arterioscler Thromb Vasc Biol 19(6), 1999
PMID: 10364071
Involvement of nuclear factor-kappaB in a murine model for the acute form of autoimmune-like toxic oil syndrome.
Bell SA, Page S, Baumgartner B, Berking C, Haas M, Eisele T, Neumeier D, Brand K., Toxicol Appl Pharmacol 157(3), 1999
PMID: 10373405
Angiotensin induces inflammatory activation of human vascular smooth muscle cells.
Kranzhöfer R, Schmidt J, Pfeiffer CA, Hagl S, Libby P, Kübler W., Arterioscler Thromb Vasc Biol 19(7), 1999
PMID: 10397679
Dietary lipid lowering reduces tissue factor expression in rabbit atheroma.
Aikawa M, Voglic SJ, Sugiyama S, Rabkin E, Taubman MB, Fallon JT, Libby P., Circulation 100(11), 1999
PMID: 10484543
Oxidative stress as a regulator of gene expression in the vasculature.
Kunsch C, Medford RM., Circ Res 85(8), 1999
PMID: 10521248
Intimal deposition of functional von Willebrand factor in atherogenesis.
De Meyer GR, Hoylaerts MF, Kockx MM, Yamamoto H, Herman AG, Bult H., Arterioscler Thromb Vasc Biol 19(10), 1999
PMID: 10521383
Complement activation by oxidatively modified low-density lipoproteins.
Demacker PN., Eur J Clin Invest 29(10), 1999
PMID: 10583420
Possible role of proinflammatory cytokines in heart allograft coronary artery disease.
Gullestad L, Simonsen S, Ueland T, Holm T, Aass H, Andreassen AK, Madsen S, Geiran O, Frøland SS, Aukrust P., Am J Cardiol 84(9), 1999
PMID: 10569653
Prolonged activation of NF-kappaB following traumatic brain injury in rats.
Nonaka M, Chen XH, Pierce JE, Leoni MJ, McIntosh TK, Wolf JA, Smith DH., J Neurotrauma 16(11), 1999
PMID: 10595819
Elevated circulating levels of C-C chemokines in patients with congestive heart failure.
Aukrust P, Ueland T, Müller F, Andreassen AK, Nordøy I, Aas H, Kjekshus J, Simonsen S, Frøland SS, Gullestad L., Circulation 97(12), 1998
PMID: 9537339
Biphasic regulation of transcription factor nuclear factor-kappaB activity in human endothelial cells by lysophosphatidylcholine through protein kinase C-mediated pathway.
Sugiyama S, Kugiyama K, Ogata N, Doi H, Ota Y, Ohgushi M, Matsumura T, Oka H, Yasue H., Arterioscler Thromb Vasc Biol 18(4), 1998
PMID: 9555862
Effect of linoleic acid on endothelial cell inflammatory mediators.
Young VM, Toborek M, Yang F, McClain CJ, Hennig B., Metabolism 47(5), 1998
PMID: 9591748
NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival.
Scatena M, Almeida M, Chaisson ML, Fausto N, Nicosia RF, Giachelli CM., J Cell Biol 141(4), 1998
PMID: 9585425
Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators.
Staels B, Koenig W, Habib A, Merval R, Lebret M, Torra IP, Delerive P, Fadel A, Chinetti G, Fruchart JC, Najib J, Maclouf J, Tedgui A., Nature 393(6687), 1998
PMID: 9655393
Redox signals and NF-kappaB activation in T cells.
Ginn-Pease ME, Whisler RL., Free Radic Biol Med 25(3), 1998
PMID: 9680181
Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa.
Rogler G, Brand K, Vogl D, Page S, Hofmeister R, Andus T, Knuechel R, Baeuerle PA, Schölmerich J, Gross V., Gastroenterology 115(2), 1998
PMID: 9679041
More cellular signals for atherogenesis?
Edgington T., Circulation 98(12), 1998
PMID: 9743503
Activated platelets induce monocyte chemotactic protein-1 secretion and surface expression of intercellular adhesion molecule-1 on endothelial cells.
Gawaz M, Neumann FJ, Dickfeld T, Koch W, Laugwitz KL, Adelsberger H, Langenbrink K, Page S, Neumeier D, Schömig A, Brand K., Circulation 98(12), 1998
PMID: 9743506
Nuclear factor kappa B: important transcription factor and therapeutic target.
Lee JI, Burckart GJ., J Clin Pharmacol 38(11), 1998
PMID: 9824778
Release of tumor necrosis factor-alpha from coronary smooth muscle: activation of NF-kappaB and inhibition by elevated cyclic AMP.
Newman WH, Zhang LM, Lee DH, Dalton ML, Warejcka DJ, Castresana MR, Leeper-Woodford SK., J Surg Res 80(2), 1998
PMID: 9878303
Early activation signals in endothelial cells. Stimulation by cytokines.
Introna M, Mantovani A., Arterioscler Thromb Vasc Biol 17(3), 1997
PMID: 9102159
Augmented adenovirus-mediated gene transfer to atherosclerotic vessels.
Ooboshi H, Rios CD, Chu Y, Christenson SD, Faraci FM, Davidson BL, Heistad DD., Arterioscler Thromb Vasc Biol 17(9), 1997
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Dysregulation of monocytic nuclear factor-kappa B by oxidized low-density lipoprotein.
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