Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion

Brand K, Page S, Rogler G, Bartsch A, Brandl R, Knuechel R, Page M, Kaltschmidt C, Baeurle PA, Neumeier D (1996)
J. Clin. Invest. 97(7): 1715-1722.

Zeitschriftenaufsatz | Veröffentlicht | Englisch

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DOI

https://doi.org/10.1172/JCI118598

Autor*in

Brand, K.; Page, S.; Rogler, G.; Bartsch, A.; Brandl, R.; Knuechel, R.; Page, M.; Kaltschmidt, Christian^UniBi; Baeurle, P.A.; Neumeier, D.

Einrichtung

Fakultät für Biologie > Zellbiologie der Tiere

Erscheinungsjahr

1996

Zeitschriftentitel

J. Clin. Invest.

Band

97

Ausgabe

7

Seite(n)

1715-1722

ISSN

0021-9738

Page URI

https://pub.uni-bielefeld.de/record/1865400

Zitieren

Brand K, Page S, Rogler G, et al. Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J. Clin. Invest. 1996;97(7):1715-1722.

Brand, K., Page, S., Rogler, G., Bartsch, A., Brandl, R., Knuechel, R., Page, M., et al. (1996). Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J. Clin. Invest., 97(7), 1715-1722. https://doi.org/10.1172/JCI118598

Brand, K., Page, S., Rogler, G., Bartsch, A., Brandl, R., Knuechel, R., Page, M., Kaltschmidt, Christian, Baeurle, P.A., and Neumeier, D. 1996. “Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion”. J. Clin. Invest. 97 (7): 1715-1722.

Brand, K., Page, S., Rogler, G., Bartsch, A., Brandl, R., Knuechel, R., Page, M., Kaltschmidt, C., Baeurle, P. A., and Neumeier, D. (1996). Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J. Clin. Invest. 97, 1715-1722.

Brand, K., et al., 1996. Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J. Clin. Invest., 97(7), p 1715-1722.

K. Brand, et al., “Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion”, J. Clin. Invest., vol. 97, 1996, pp. 1715-1722.

Brand, K., Page, S., Rogler, G., Bartsch, A., Brandl, R., Knuechel, R., Page, M., Kaltschmidt, C., Baeurle, P.A., Neumeier, D.: Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J. Clin. Invest. 97, 1715-1722 (1996).

Brand, K., Page, S., Rogler, G., Bartsch, A., Brandl, R., Knuechel, R., Page, M., Kaltschmidt, Christian, Baeurle, P.A., and Neumeier, D. “Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion”. J. Clin. Invest. 97.7 (1996): 1715-1722.

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Myeloid-specific IκB kinase β deficiency decreases atherosclerosis in low-density lipoprotein receptor-deficient mice.
Park SH, Sui Y, Gizard F, Xu J, Rios-Pilier J, Helsley RN, Han SS, Zhou C., Arterioscler Thromb Vasc Biol 32(12), 2012
PMID: 23023371

Retinol-binding protein 4 induces inflammation in human endothelial cells by an NADPH oxidase- and nuclear factor kappa B-dependent and retinol-independent mechanism.
Farjo KM, Farjo RA, Halsey S, Moiseyev G, Ma JX., Mol Cell Biol 32(24), 2012
PMID: 23071093

Ginseng Berry Extract Prevents Atherogenesis via Anti-Inflammatory Action by Upregulating Phase II Gene Expression.
Kim CK, Cho DH, Lee KS, Lee DK, Park CW, Kim WG, Lee SJ, Ha KS, Goo Taeg O, Kwon YG, Kim YM., Evid Based Complement Alternat Med 2012(), 2012
PMID: 23243449

Docosahexaenoic acid attenuates VCAM-1 expression and NF-κB activation in TNF-α-treated human aortic endothelial cells.
Wang TM, Chen CJ, Lee TS, Chao HY, Wu WH, Hsieh SC, Sheu HH, Chiang AN., J Nutr Biochem 22(2), 2011
PMID: 20573493

NF-κB, inflammation, and metabolic disease.
Baker RG, Hayden MS, Ghosh S., Cell Metab 13(1), 2011
PMID: 21195345

Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives.
Chiu JJ, Chien S., Physiol Rev 91(1), 2011
PMID: 21248169

IKKβ regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways.
Ashida N, Senbanerjee S, Kodama S, Foo SY, Coggins M, Spencer JA, Zamiri P, Shen D, Li L, Sciuto T, Dvorak A, Gerszten RE, Lin CP, Karin M, Rosenzweig A., Nat Commun 2(), 2011
PMID: 21587235

Rho kinase inhibition by fasudil has anti-inflammatory effects in hypercholesterolemic rats.
Ma Z, Zhang J, Du R, Ji E, Chu L., Biol Pharm Bull 34(11), 2011
PMID: 22040880

Histamine deficiency decreases atherosclerosis and inflammatory response in apolipoprotein E knockout mice independently of serum cholesterol level.
Wang KY, Tanimoto A, Guo X, Yamada S, Shimajiri S, Murata Y, Ding Y, Tsutsui M, Kato S, Watanabe T, Ohtsu H, Hirano K, Kohno K, Sasaguri Y., Arterioscler Thromb Vasc Biol 31(4), 2011
PMID: 21273563

Apolipoprotein E induces antiinflammatory phenotype in macrophages.
Baitsch D, Bock HH, Engel T, Telgmann R, Müller-Tidow C, Varga G, Bot M, Herz J, Robenek H, von Eckardstein A, Nofer JR., Arterioscler Thromb Vasc Biol 31(5), 2011
PMID: 21350196

Myeloid IκBα deficiency promotes atherogenesis by enhancing leukocyte recruitment to the plaques.
Goossens P, Vergouwe MN, Gijbels MJ, Curfs DM, van Woezik JH, Hoeksema MA, Xanthoulea S, Leenen PJ, Rupec RA, Hofker MH, de Winther MP., PLoS One 6(7), 2011
PMID: 21814576

Targeting N-acetylglucosamine-bearing polymer-coated liposomes to vascular smooth muscle cells.
Ise M, Ise H, Shiba Y, Kobayashi S, Goto M, Takahashi M, Akaike T, Ikeda U., J Artif Organs 14(4), 2011
PMID: 21809097

The fatty acid oxidation product 15-A3t-isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation.
Brooks JD, Musiek ES, Koestner TR, Stankowski JN, Howard JR, Brunoldi EM, Porta A, Zanoni G, Vidari G, Morrow JD, Milne GL, McLaughlin B., J Neurochem 119(3), 2011
PMID: 21838782

Down-regulation of matrix metalloproteinase-9 by pyrrolidine dithiocarbamate prevented retinal ganglion cell death after transection of optic nerve in rats.
Sun MH, Chen KJ, Tsao YP, Kao LY, Han WH, Lin KK, Pang JH., Curr Eye Res 36(11), 2011
PMID: 21999230

Inhibition of NF-κB prevents high glucose-induced proliferation and plasminogen activator inhibitor-1 expression in vascular smooth muscle cells.
Jeong IK, Oh DH, Park SJ, Kang JH, Kim S, Lee MS, Kim MJ, Hwang YC, Ahn KJ, Chung HY, Chae MK, Yoo HJ., Exp Mol Med 43(12), 2011
PMID: 21975282

Modulation of human T cells signaling transduction by lovastatin.
Cheng SM, Lai JH, Yang SP, Tsao TP, Ho LJ, Liou JT, Cheng CC., Int J Cardiol 140(1), 2010
PMID: 19046782

Innate immune signals in atherosclerosis.
Lundberg AM, Hansson GK., Clin Immunol 134(1), 2010
PMID: 19740706

Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis.
Orr AW, Hastings NE, Blackman BR, Wamhoff BR., J Vasc Res 47(2), 2010
PMID: 19851078

The effect of the long term aspirin administration on the progress of atherosclerosis in apoE-/- LDLR-/- double knockout mouse.
Yamamoto Y, Yamashita T, Kitagawa F, Sakamoto K, Giddings JC, Yamamoto J., Thromb Res 125(3), 2010
PMID: 20005558

Panax notoginseng saponins attenuate atherogenesis accelerated by zymosan in rabbits.
Liu Y, Zhang HG, Jia Y, Li XH., Biol Pharm Bull 33(8), 2010
PMID: 20686226

Preventive effect of a proteasome inhibitor on the formation of accelerated atherosclerosis in rabbits with uremia.
Feng B, Zhang Y, Mu J, Ye Z, Zeng W, Qi W, Luo Z, Guo Y, Yang X, Yuan F., J Cardiovasc Pharmacol 55(2), 2010
PMID: 19935080

Role of nuclear factor kappaB in cardiovascular health and disease.
Van der Heiden K, Cuhlmann S, Luong le A, Zakkar M, Evans PC., Clin Sci (Lond) 118(10), 2010
PMID: 20175746

NF-kappaB activation stimulates osteogenic differentiation of mesenchymal stem cells derived from human adipose tissue by increasing TAZ expression.
Cho HH, Shin KK, Kim YJ, Song JS, Kim JM, Bae YC, Kim CD, Jung JS., J Cell Physiol 223(1), 2010
PMID: 20049872

Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation.
Feaver RE, Gelfand BD, Wang C, Schwartz MA, Blackman BR., Circ Res 106(11), 2010
PMID: 20378855

Mechanisms underlying the cardioprotective effects of omega-3 polyunsaturated fatty acids.
Adkins Y, Kelley DS., J Nutr Biochem 21(9), 2010
PMID: 20382009

Regulation of IkappaBalpha function and NF-kappaB signaling: AEBP1 is a novel proinflammatory mediator in macrophages.
Majdalawieh A, Ro HS., Mediators Inflamm 2010(), 2010
PMID: 20396415

SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis.
Stein S, Lohmann C, Schäfer N, Hofmann J, Rohrer L, Besler C, Rothgiesser KM, Becher B, Hottiger MO, Borén J, McBurney MW, Landmesser U, Lüscher TF, Matter CM., Eur Heart J 31(18), 2010
PMID: 20418343

Glycyrrhetinic acid inhibits ICAM-1 expression via blocking JNK and NF-kappaB pathways in TNF-alpha-activated endothelial cells.
Chang YL, Chen CL, Kuo CL, Chen BC, You JS., Acta Pharmacol Sin 31(5), 2010
PMID: 20418897

Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis.
Huang Q, Pope RM., J Leukoc Biol 88(2), 2010
PMID: 20484668

Osteoarthritis: another component of metabolic syndrome?
Velasquez MT, Katz JD., Metab Syndr Relat Disord 8(4), 2010
PMID: 20367223

Regulation of cell proliferation by the opioid growth factor receptor is dependent on karyopherin beta and Ran for nucleocytoplasmic trafficking.
Cheng F, McLaughlin PJ, Zagon IS., Exp Biol Med (Maywood) 235(9), 2010
PMID: 20705629

The role of monocytes in atherosclerotic coronary artery disease.
Pamukcu B, Lip GY, Devitt A, Griffiths H, Shantsila E., Ann Med 42(6), 2010
PMID: 20568979

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB): a new potential therapeutic target in atherosclerosis?
Dąbek J, Kułach A, Gąsior Z., Pharmacol Rep 62(5), 2010
PMID: 21098861

Immunohistochemical and Stereologic Analysis of NF-κB Activation in Chronic Periodontitis.
Arabaci T, Cicek Y, Canakci V, Canakci CF, Ozgoz M, Albayrak M, Keles ON., Eur J Dent 4(4), 2010
PMID: 20922166

The I{kappa}B kinase inhibitor nuclear factor-{kappa}B essential modulator-binding domain peptide for inhibition of injury-induced neointimal formation.
Grassia G, Maddaluno M, Musilli C, De Stefano D, Carnuccio R, Di Lauro MV, Parratt CA, Kennedy S, Di Meglio P, Ianaro A, Maffia P, Parenti A, Ialenti A., Arterioscler Thromb Vasc Biol 30(12), 2010
PMID: 20930169

Treating atherosclerosis: the potential of Toll-like receptors as therapeutic targets.
Cole JE, Mitra AT, Monaco C., Expert Rev Cardiovasc Ther 8(11), 2010
PMID: 21090937

Bio-incompatibility and Th2 polarization during regular dialysis treatment.
Libetta C, Sepe V, Dal Canton A., Int Rev Immunol 29(6), 2010
PMID: 21073329

Molecular inflammation: underpinnings of aging and age-related diseases.
Chung HY, Cesari M, Anton S, Marzetti E, Giovannini S, Seo AY, Carter C, Yu BP, Leeuwenburgh C., Ageing Res Rev 8(1), 2009
PMID: 18692159

Cilostazol inhibits cytokine-induced nuclear factor-kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells.
Hattori Y, Suzuki K, Tomizawa A, Hirama N, Okayasu T, Hattori S, Satoh H, Akimoto K, Kasai K., Cardiovasc Res 81(1), 2009
PMID: 18703532

Activation of transcription factors and gene expression by oxidized low-density lipoprotein.
Mazière C, Mazière JC., Free Radic Biol Med 46(2), 2009
PMID: 18996472

The role of RAGE in aminoguanidine-induced suppression of venous intimal hyperplasia in diabetic rats.
Wang X, Diao Y, Zhang H, Huo X, Zhang Q., Ann Vasc Surg 23(2), 2009
PMID: 19110400

Insulin-like growth factor-1 receptor expression masks the antiinflammatory and glucose uptake capacity of insulin in vascular smooth muscle cells.
Engberding N, San Martín A, Martin-Garrido A, Koga M, Pounkova L, Lyons E, Lassègue B, Griendling KK., Arterioscler Thromb Vasc Biol 29(3), 2009
PMID: 19122171

Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans.
Pierce GL, Lesniewski LA, Lawson BR, Beske SD, Seals DR., Circulation 119(9), 2009
PMID: 19237660

Translational mini-review series on immunology of vascular disease: inflammation, infections and Toll-like receptors in cardiovascular disease.
Ward JR, Wilson HL, Francis SE, Crossman DC, Sabroe I., Clin Exp Immunol 156(3), 2009
PMID: 19309349

Nanoparticle-mediated delivery of nuclear factor kappaB decoy into lungs ameliorates monocrotaline-induced pulmonary arterial hypertension.
Kimura S, Egashira K, Chen L, Nakano K, Iwata E, Miyagawa M, Tsujimoto H, Hara K, Morishita R, Sueishi K, Tominaga R, Sunagawa K., Hypertension 53(5), 2009
PMID: 19307469

The renin-angiotensin system modulates inflammatory processes in atherosclerosis: evidence from basic research and clinical studies.
Montecucco F, Pende A, Mach F., Mediators Inflamm 2009(), 2009
PMID: 19390623

Induction of MIF expression by oxidized LDL via activation of NF-kappaB in vascular smooth muscle cells.
Chen L, Yang G, Zhang X, Wu J, Gu Q, Wei M, Yang J, Zhu Y, Wang N, Guan Y., Atherosclerosis 207(2), 2009
PMID: 19640536

Considering TWEAK as a target for therapy in renal and vascular injury.
Ortiz A, Sanz AB, Muñoz García B, Moreno JA, Sánchez Niño MD, Martín-Ventura JL, Egido J, Blanco-Colio LM., Cytokine Growth Factor Rev 20(3), 2009
PMID: 19482507

Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes.
Newby AC, George SJ, Ismail Y, Johnson JL, Sala-Newby GB, Thomas AC., Thromb Haemost 101(6), 2009
PMID: 19492140

Role of NF-kappa B in the pathogenesis of diabetes and its associated complications.
Patel S, Santani D., Pharmacol Rep 61(4), 2009
PMID: 19815941

Nuclear factor-kappaB regulates estrogen receptor-alpha transcription in the human heart.
Mahmoodzadeh S, Fritschka S, Dworatzek E, Pham TH, Becher E, Kuehne A, Davidson MM, Regitz-Zagrosek V., J Biol Chem 284(37), 2009
PMID: 19584059

RAGE, vascular tone and vascular disease.
Farmer DG, Kennedy S., Pharmacol Ther 124(2), 2009
PMID: 19616578

Primate models in women's health: inflammation and atherogenesis in female cynomolgus macaques (Macaca fascicularis).
Register TC., Am J Primatol 71(9), 2009
PMID: 19530126

Metformin inhibits nuclear factor kappaB activation and decreases serum high-sensitivity C-reactive protein level in experimental atherogenesis of rabbits.
Li SN, Wang X, Zeng QT, Feng YB, Cheng X, Mao XB, Wang TH, Deng HP., Heart Vessels 24(6), 2009
PMID: 20108078

Overexpression of activated nuclear factor-kappa B in aorta of patients with coronary atherosclerosis.
Zhang W, Xing SS, Sun XL, Xing QC., Clin Cardiol 32(12), 2009
PMID: 20014193

Importance of pericytes and mechanisms of pericyte loss during diabetes retinopathy.
Ejaz S, Chekarova I, Ejaz A, Sohail A, Lim CW., Diabetes Obes Metab 10(1), 2008
PMID: 17941874

Homocysteine stimulates monocyte chemoattractant protein-1 expression in the kidney via nuclear factor-kappaB activation.
Hwang SY, Woo CW, Au-Yeung KK, Siow YL, Zhu TY, O K., Am J Physiol Renal Physiol 294(1), 2008
PMID: 17977907

Anti-inflammatory interventions of NF-kappaB signaling: potential applications and risks.
Uwe S., Biochem Pharmacol 75(8), 2008
PMID: 18070616

Bioactive lipids in metabolic syndrome.
Nagao K, Yanagita T., Prog Lipid Res 47(2), 2008
PMID: 18177744

Proinsulin C-peptide: friend or foe in the development of diabetes-associated complications?
Nordquist L, Johansson M., Vasc Health Risk Manag 4(6), 2008
PMID: 19337542

NF-kappaB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK.
Liu GH, Qu J, Shen X., Biochim Biophys Acta 1783(5), 2008
PMID: 18241676

Possible role of NFkappaB in the embryonic vascular remodeling and the endothelial mesenchymal transition process.
Arciniegas E, Carrillo LM, De Sanctis JB, Candelle D., Cell Adh Migr 2(1), 2008
PMID: 19262121

Homocysteine stimulates monocyte chemoattractant protein-1 expression in mesangial cells via NF-kappaB activation.
Cheung GT, Siow YL, O K., Can J Physiol Pharmacol 86(3), 2008
PMID: 18418435

The profile of gene expression and role of nuclear factor kappa B on glomerular injury in rats with Thy-1 nephritis.
Wang H, Jiang XM, Xu JH, Xu J, Tong JX, Wang YW., Clin Exp Immunol 152(3), 2008
PMID: 18422731

The anti-atherosclerotic effect of olive leaf extract is related to suppressed inflammatory response in rabbits with experimental atherosclerosis.
Wang L, Geng C, Jiang L, Gong D, Liu D, Yoshimura H, Zhong L., Eur J Nutr 47(5), 2008
PMID: 18654736

Baicalein attenuates intimal hyperplasia after rat carotid balloon injury through arresting cell-cycle progression and inhibiting ERK, Akt, and NF-kappaB activity in vascular smooth-muscle cells.
Peng CY, Pan SL, Huang YW, Guh JH, Chang YL, Teng CM., Naunyn Schmiedebergs Arch Pharmacol 378(6), 2008
PMID: 18663431

p21-activated kinase signaling regulates oxidant-dependent NF-kappa B activation by flow.
Orr AW, Hahn C, Blackman BR, Schwartz MA., Circ Res 103(6), 2008
PMID: 18669917

Endothelial dysfunction: from molecular mechanisms to measurement, clinical implications, and therapeutic opportunities.
Le Brocq M, Leslie SJ, Milliken P, Megson IL., Antioxid Redox Signal 10(9), 2008
PMID: 18598143

Homocysteine-induced enhanced expression of tissue factor in human vascular smooth muscle cells.
Liu F, Huang R, Yao J, Wei W, Hu Y, Song S, Li J., J Huazhong Univ Sci Technolog Med Sci 28(5), 2008
PMID: 18846330

Increased tissue transglutaminase expression in human atherosclerotic coronary arteries.
Cho BR, Kim MK, Suh DH, Hahn JH, Lee BG, Choi YC, Kwon TJ, Kim SY, Kim DJ., Coron Artery Dis 19(7), 2008
PMID: 18923241

Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis.
Gareus R, Kotsaki E, Xanthoulea S, van der Made I, Gijbels MJ, Kardakaris R, Polykratis A, Kollias G, de Winther MP, Pasparakis M., Cell Metab 8(5), 2008
PMID: 19046569

The role and regulation of the nuclear factor kappa B signalling pathway in human labour.
Lappas M, Rice GE., Placenta 28(5-6), 2007
PMID: 16843526

Reduced oxidative stress promotes NF-kappaB-mediated neuroprotective gene expression after transient focal cerebral ischemia: lymphocytotrophic cytokines and antiapoptotic factors.
Song YS, Lee YS, Narasimhan P, Chan PH., J Cereb Blood Flow Metab 27(4), 2007
PMID: 16868554

IKKalpha and IKKbeta function in TNFalpha-stimulated adhesion molecule expression in human aortic smooth muscle cells.
MacKenzie CJ, Ritchie E, Paul A, Plevin R., Cell Signal 19(1), 2007
PMID: 16872805

Macrophage-specific inhibition of NF-kappaB activation reduces foam-cell formation.
Ferreira V, van Dijk KW, Groen AK, Vos RM, van der Kaa J, Gijbels MJ, Havekes LM, Pannekoek H., Atherosclerosis 192(2), 2007
PMID: 16938301

Ethanol beverages containing polyphenols decrease nuclear factor kappa-B activation in mononuclear cells and circulating MCP-1 concentrations in healthy volunteers during a fat-enriched diet.
Blanco-Colio LM, Muñoz-García B, Martín-Ventura JL, Alvarez-Sala LA, Castilla M, Bustamante A, Lamuela-Raventós RM, Gómez-Gerique J, Fernández-Cruz A, Millán J, Egido J., Atherosclerosis 192(2), 2007
PMID: 16970955

Ozonized low density lipoprotein (ozLDL) inhibits NF-kappaB and IRAK-1-associated signaling.
Cappello C, Saugel B, Huth KC, Zwergal A, Krautkrämer M, Furman C, Rouis M, Wieser B, Schneider HW, Neumeier D, Brand K., Arterioscler Thromb Vasc Biol 27(1), 2007
PMID: 17053167

Mulberry leaf aqueous fractions inhibit TNF-alpha-induced nuclear factor kappaB (NF-kappaB) activation and lectin-like oxidized LDL receptor-1 (LOX-1) expression in vascular endothelial cells.
Shibata Y, Kume N, Arai H, Hayashida K, Inui-Hayashida A, Minami M, Mukai E, Toyohara M, Harauma A, Murayama T, Kita T, Hara S, Kamei K, Yokode M., Atherosclerosis 193(1), 2007
PMID: 17055514

Protective effects of magnolol against oxidized LDL-induced apoptosis in endothelial cells.
Ou HC, Chou FP, Sheu WH, Hsu SL, Lee WJ., Arch Toxicol 81(6), 2007
PMID: 17216433

Nitric oxide in blood. The nitrosative-oxidative disequilibrium hypothesis on the pathogenesis of cardiovascular disease.
Elahi MM, Naseem KM, Matata BM., FEBS J 274(4), 2007
PMID: 17244198

25-Hydroxycholesterol, 7beta-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages.
Erridge C, Webb DJ, Spickett CM., Free Radic Res 41(3), 2007
PMID: 17364953

Influence of stress and nutrition on cattle immunity.
Carroll JA, Forsberg NE., Vet Clin North Am Food Anim Pract 23(1), 2007
PMID: 17382844

Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet.
Mehta JL, Sanada N, Hu CP, Chen J, Dandapat A, Sugawara F, Satoh H, Inoue K, Kawase Y, Jishage K, Suzuki H, Takeya M, Schnackenberg L, Beger R, Hermonat PL, Thomas M, Sawamura T., Circ Res 100(11), 2007
PMID: 17478727

Direct evidence of endothelial oxidative stress with aging in humans: relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-kappaB.
Donato AJ, Eskurza I, Silver AE, Levy AS, Pierce GL, Gates PE, Seals DR., Circ Res 100(11), 2007
PMID: 17478731

Apolipoprotein E interrupts interleukin-1beta signaling in vascular smooth muscle cells.
Kawamura A, Baitsch D, Telgmann R, Feuerborn R, Weissen-Plenz G, Hagedorn C, Saku K, Brand-Herrmann SM, von Eckardstein A, Assmann G, Nofer JR., Arterioscler Thromb Vasc Biol 27(7), 2007
PMID: 17510469

Suppression of complement regulatory protein C1 inhibitor in vascular endothelial activation by inhibiting vascular cell adhesion molecule-1 action.
Zhang H, Qin G, Liang G, Li J, Chiu I, Barrington RA, Liu D., Biochem Biophys Res Commun 358(4), 2007
PMID: 17521609

Homocysteine induces VCAM-1 gene expression through NF-kappaB and NAD(P)H oxidase activation: protective role of Mediterranean diet polyphenolic antioxidants.
Carluccio MA, Ancora MA, Massaro M, Carluccio M, Scoditti E, Distante A, Storelli C, De Caterina R., Am J Physiol Heart Circ Physiol 293(4), 2007
PMID: 17586618

In vivo reduction of the nuclear factor-kappaB activity using synthetic cis-element decoy oligonucleotides suppresses intimal hyperplasia in the injured carotid arteries in rabbits.
Takeuchi K, Itoh H, Yonemitsu Y, Matsumoto T, Kume M, Komori K, Maehara Y., Surg Today 37(7), 2007
PMID: 17593477

Nanoparticles-a thoracic toxicology perspective.
Duffin R, Mills NL, Donaldson K., Yonsei Med J 48(4), 2007
PMID: 17722227

Acetylbritannilactone suppresses lipopolysaccharide-induced vascular smooth muscle cell inflammatory response.
Liu YP, Wen JK, Zheng B, Zhang DQ, Han M., Eur J Pharmacol 577(1-3), 2007
PMID: 17915214

Nitric oxide and mitochondrial signaling: from physiology to pathophysiology.
Erusalimsky JD, Moncada S., Arterioscler Thromb Vasc Biol 27(12), 2007
PMID: 17885213

Increased expression of nuclear NF-kappaB after coronary artery balloon injury can be inhibited by intracoronary beta-irradiation.
Su CH, Hsieh BT, Leung SW, Wu CJ, Chiu SY, Lin CS., Int J Radiat Biol 83(10), 2007
PMID: 17729165

A nuclear factor-kappaB inhibitor pyrrolidine dithiocarbamate ameliorates pulmonary hypertension in rats.
Sawada H, Mitani Y, Maruyama J, Jiang BH, Ikeyama Y, Dida FA, Yamamoto H, Imanaka-Yoshida K, Shimpo H, Mizoguchi A, Maruyama K, Komada Y., Chest 132(4), 2007
PMID: 17934115

Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming.
Hastings NE, Simmers MB, McDonald OG, Wamhoff BR, Blackman BR., Am J Physiol Cell Physiol 293(6), 2007
PMID: 17913848

Vascular oxidant stress and inflammation in hyperhomocysteinemia.
Papatheodorou L, Weiss N., Antioxid Redox Signal 9(11), 2007
PMID: 17822365

Regulation of Src homology 2-containing protein tyrosine phosphatase by advanced glycation end products: the role on atherosclerosis in diabetes.
Seki N, Hashimoto N, Taira M, Yagi S, Yoshida Y, Ishikawa K, Suzuki Y, Sano H, Horiuchi S, Yoshida S, Sakurai K, Yagui K, Makino H, Saito Y., Metabolism 56(11), 2007
PMID: 17950112

High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway.
Ho FM, Lin WW, Chen BC, Chao CM, Yang CR, Lin LY, Lai CC, Liu SH, Liau CS., Cell Signal 18(3), 2006
PMID: 15970429

Trace element status in Saudi patients with established atherosclerosis.
Alissa EM, Bahjri SM, Ahmed WH, Al-Ama N, Ferns GA., J Trace Elem Med Biol 20(2), 2006
PMID: 16785050

Metformin inhibits proinflammatory responses and nuclear factor-kappaB in human vascular wall cells.
Isoda K, Young JL, Zirlik A, MacFarlane LA, Tsuboi N, Gerdes N, Schönbeck U, Libby P., Arterioscler Thromb Vasc Biol 26(3), 2006
PMID: 16385087

Cytokine stimulation of pregnancy-associated plasma protein A expression in human coronary artery smooth muscle cells: inhibition by resveratrol.
Conover CA, Bale LK, Harrington SC, Resch ZT, Overgaard MT, Oxvig C., Am J Physiol Cell Physiol 290(1), 2006
PMID: 16338976

Endothelial cell heterogeneity and atherosclerosis.
Aird WC., Curr Atheroscler Rep 8(1), 2006
PMID: 16455017

Folic acid inhibits homocysteine-induced superoxide anion production and nuclear factor kappa B activation in macrophages.
Au-Yeung KK, Yip JC, Siow YL, O K., Can J Physiol Pharmacol 84(1), 2006
PMID: 16845898

Effects of simvastatin on NF-kappaB-DNA binding activity and monocyte chemoattractant protein-1 expression in a rabbit model of atherosclerosis.
Yang X, Wang L, Zeng H, Dubey L, Zhou N, Pu J., J Huazhong Univ Sci Technolog Med Sci 26(2), 2006
PMID: 16850745

Inhibition of the ubiquitin-proteasome system: a new avenue for atherosclerosis.
Tan C, Li Y, Tan X, Pan H, Huang W., Clin Chem Lab Med 44(10), 2006
PMID: 17032134

Toll-like receptor 4 polymorphism is associated with coronary stenosis but not with the occurrence of acute or old myocardial infarctions.
Hernesniemi J, Lehtimäki T, Rontu R, Islam MS, Eklund C, Mikkelsson J, Ilveskoski E, Kajander O, Goebeler S, Viiri LE, Hurme M, Karhunen PJ., Scand J Clin Lab Invest 66(8), 2006
PMID: 17101559

6A3-5/Osa2 is an early activated gene implicated in the control of vascular smooth muscle cell functions.
Garin G, Zibara K, Aguilar F, Lo M, Hurlstone A, Poston R, Mcgregor JL., J Biomed Biotechnol 2006(5), 2006
PMID: 17489020

Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response.
Tzima E., Circ Res 98(2), 2006
PMID: 16456110

TNFalpha induces ABCA1 through NF-kappaB in macrophages and in phagocytes ingesting apoptotic cells.
Gerbod-Giannone MC, Li Y, Holleboom A, Han S, Hsu LC, Tabas I, Tall AR., Proc Natl Acad Sci U S A 103(9), 2006
PMID: 16492740

The good fat hormone: adiponectin and cardiovascular disease.
Do D, Alvarez J, Chiquette E, Chilton R., Curr Atheroscler Rep 8(2), 2006
PMID: 16510042

Nuclear factor-kappaB p65 and upregulation of interleukin-6 in retinal ischemia/reperfusion injury in rats.
Wang J, Jiang S, Kwong JM, Sanchez RN, Sadun AA, Lam TT., Brain Res 1081(1), 2006
PMID: 16530172

Cytokines in atherosclerosis: pathogenic and regulatory pathways.
Tedgui A, Mallat Z., Physiol Rev 86(2), 2006
PMID: 16601268

[LDL: from metabolic syndrome to instability of the atherosclerotic plaque].
Siqueira AF, Abdalla DS, Ferreira SR., Arq Bras Endocrinol Metabol 50(2), 2006
PMID: 16767300

Hepatocyte growth factor protects human endothelial cells against advanced glycation end products-induced apoptosis.
Zhou YJ, Wang JH, Zhang J., Biochem Biophys Res Commun 344(2), 2006
PMID: 16630544

Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells.
Hattori Y, Suzuki K, Hattori S, Kasai K., Hypertension 47(6), 2006
PMID: 16636195

Transcription factor and kinase-mediated signaling in atherosclerosis and vascular injury.
Adhikari N, Charles N, Lehmann U, Hall JL., Curr Atheroscler Rep 8(3), 2006
PMID: 16640963

Parthenolide modulates the NF-kappaB-mediated inflammatory responses in experimental atherosclerosis.
López-Franco O, Hernández-Vargas P, Ortiz-Muñoz G, Sanjuán G, Suzuki Y, Ortega L, Blanco J, Egido J, Gómez-Guerrero C., Arterioscler Thromb Vasc Biol 26(8), 2006
PMID: 16741149

Inhibitory effects of NFkappaB decoy oligodeoxynucleotides on neointimal hyperplasia in a rabbit vein graft model.
Miyake T, Aoki M, Shiraya S, Tanemoto K, Ogihara T, Kaneda Y, Morishita R., J Mol Cell Cardiol 41(3), 2006
PMID: 16762361

Proteasome inhibition attenuates lung injury induced by intestinal ischemia reperfusion in rats.
Tian XF, Zhang XS, Li YH, Wang ZZ, Zhang F, Wang LM, Yao JH., Life Sci 79(22), 2006
PMID: 16875703

Cytochrome P450 epoxygenase CYP2J2 and the risk of coronary artery disease.
Spiecker M, Liao J., Trends Cardiovasc Med 16(6), 2006
PMID: 16839864

Glucose control with insulin results in reduction of NF-kappaB-binding activity in mononuclear blood cells of patients with recently manifested type 1 diabetes.
Schiekofer S, Galasso G, Andrassy M, Aprahamian T, Schneider J, Rocnik E., Diabetes Obes Metab 8(5), 2006
PMID: 16918581

Ursane triterpenoids inhibit atherosclerosis and xanthoma in LDL receptor knockout mice.
Zhang Q, Chang Z, Wang Q., Cardiovasc Drugs Ther 20(5), 2006
PMID: 17136324

Stent-based local delivery of nuclear factor-kappaB decoy attenuates in-stent restenosis in hypercholesterolemic rabbits.
Ohtani K, Egashira K, Nakano K, Zhao G, Funakoshi K, Ihara Y, Kimura S, Tominaga R, Morishita R, Sunagawa K., Circulation 114(25), 2006
PMID: 17130346

Induction of neutrophil gelatinase-associated lipocalin in vascular injury via activation of nuclear factor-kappaB.
Bu DX, Hemdahl AL, Gabrielsen A, Fuxe J, Zhu C, Eriksson P, Yan ZQ., Am J Pathol 169(6), 2006
PMID: 17148685

A selective NFkappaB inhibitor, DHMEQ, reduced atherosclerosis in ApoE-deficient mice.
Chiba T, Kondo Y, Shinozaki S, Kaneko E, Ishigami A, Maruyama N, Umezawa K, Shimokado K., J Atheroscler Thromb 13(6), 2006
PMID: 17192695

Concurrent treatment with renin-angiotensin system blockers and acetylsalicylic acid reduces nuclear factor kappaB activation and C-reactive protein expression in human carotid artery plaques.
Sattler KJ, Woodrum JE, Galili O, Olson M, Samee S, Meyer FB, Zhu XY, Lerman LO, Lerman A., Stroke 36(1), 2005
PMID: 15576654

Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids.
Spiecker M, Liao JK., Arch Biochem Biophys 433(2), 2005
PMID: 15581597

The proteasome: a central regulator of inflammation and macrophage function.
Qureshi N, Vogel SN, Van Way C, Papasian CJ, Qureshi AA, Morrison DC., Immunol Res 31(3), 2005
PMID: 15888915

Distinct NF-kappaB regulation by shear stress through Ras-dependent IkappaBalpha oscillations: real-time analysis of flow-mediated activation in live cells.
Ganguli A, Persson L, Palmer IR, Evans I, Yang L, Smallwood R, Black R, Qwarnstrom EE., Circ Res 96(6), 2005
PMID: 15731464

Nuclear factor kappaB signaling in atherogenesis.
de Winther MP, Kanters E, Kraal G, Hofker MH., Arterioscler Thromb Vasc Biol 25(5), 2005
PMID: 15731497

Liver X receptor agonists inhibit tissue factor expression in macrophages.
Terasaka N, Hiroshima A, Ariga A, Honzumi S, Koieyama T, Inaba T, Fujiwara T., FEBS J 272(6), 2005
PMID: 15752369

Insulin alters nuclear factor-lambdaB and peroxisome proliferator-activated receptor-gamma protein expression induced by glycated bovine serum albumin in vascular smooth-muscle cells.
De Oliveira C, Colette C, Monnier L, Descomps B, Pares-Herbute N., J Lab Clin Med 145(3), 2005
PMID: 15871306

Roxithromycin is an inhibitor of human coronary artery smooth muscle cells proliferation: a potential ability to prevent coronary heart disease.
Tomita H, Osanai T, Toki T, Maeda N, Murakami R, Chen Z, Yamabe H, Osawa H, Yasujima M, Okumura K., Atherosclerosis 182(1), 2005
PMID: 16115478

The subendothelial extracellular matrix modulates NF-kappaB activation by flow: a potential role in atherosclerosis.
Orr AW, Sanders JM, Bevard M, Coleman E, Sarembock IJ, Schwartz MA., J Cell Biol 169(1), 2005
PMID: 15809308

Regulation of vascular smooth muscle cell proliferation: role of NF-kappaB revisited.
Mehrhof FB, Schmidt-Ullrich R, Dietz R, Scheidereit C., Circ Res 96(9), 2005
PMID: 15831813

Local administration of NF-kappa B decoy oligonucleotides to prevent restenosis after balloon angioplasty: an experimental study in New Zealand white rabbits.
Kalinowski M, Viehofer K, Hamann C, Barry JJ, Kleb B, Klose KJ, Wagner HJ, Alfke H., Cardiovasc Intervent Radiol 28(3), 2005
PMID: 15886949

Expression of activated transcription factor nuclear factor-kappaB in periodontally diseased tissues.
Ambili R, Santhi WS, Janam P, Nandakumar K, Pillai MR., J Periodontol 76(7), 2005
PMID: 16018758

Relevance of oxidative pathways in the pathophysiology of chronic kidney disease.
Himmelfarb J., Cardiol Clin 23(3), 2005
PMID: 16084281

Tendon xanthomas in familial hypercholesterolemia are associated with a differential inflammatory response of macrophages to oxidized LDL.
Artieda M, Cenarro A, Junquera C, Lasierra P, Martínez-Lorenzo MJ, Pocoví M, Civeira F., FEBS Lett 579(20), 2005
PMID: 16083882

12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB.
Bolick DT, Orr AW, Whetzel A, Srinivasan S, Hatley ME, Schwartz MA, Hedrick CC., Arterioscler Thromb Vasc Biol 25(11), 2005
PMID: 16166569

Nuclear factor kappa B signaling in macrophage function and atherogenesis.
Xanthoulea S, Curfs DM, Hofker MH, de Winther MP., Curr Opin Lipidol 16(5), 2005
PMID: 16148538

Suppression of vascular cell adhesion molecule-1 expression by crocetin contributes to attenuation of atherosclerosis in hypercholesterolemic rabbits.
Zheng S, Qian Z, Tang F, Sheng L., Biochem Pharmacol 70(8), 2005
PMID: 16154540

Involvement of c-Jun NH2 terminal kinase and p38MAPK in rapamycin-mediated inhibition of neointimal formation in rat carotid arteries.
Omura T, Yoshiyama M, Izumi Y, Kim S, Matsumoto R, Enomoto S, Kusuyama T, Nishiya D, Nakamura Y, Akioka K, Iwao H, Takeuchi K, Yoshikawa J., J Cardiovasc Pharmacol 46(4), 2005
PMID: 16160607

Anti-inflammatory effects of polyunsaturated fatty acids in THP-1 cells.
Zhao G, Etherton TD, Martin KR, Vanden Heuvel JP, Gillies PJ, West SG, Kris-Etherton PM., Biochem Biophys Res Commun 336(3), 2005
PMID: 16169525

Relationship between reduced BCL-2 expression in circulating mononuclear cells and early nephropathy in type 1 diabetes.
Cipollone F, Chiarelli F, Iezzi A, Fazia ML, Cuccurullo C, Pini B, De Cesare D, Torello M, Tumini S, Cuccurullo F, Mezzetti A., Int J Immunopathol Pharmacol 18(4), 2005
PMID: 16388709

Reactive oxygen species mediates homocysteine-induced mitochondrial biogenesis in human endothelial cells: modulation by antioxidants.
Perez-de-Arce K, Foncea R, Leighton F., Biochem Biophys Res Commun 338(2), 2005
PMID: 16259958

Helper T cells and atherosclerosis: the cytokine web.
Baidya SG, Zeng QT., Postgrad Med J 81(962), 2005
PMID: 16344296

Hyperhomocysteinemia activates nuclear factor-kappaB in endothelial cells via oxidative stress.
Au-Yeung KK, Woo CW, Sung FL, Yip JC, Siow YL, O K., Circ Res 94(1), 2004
PMID: 14630727

Methionine-induced hyperhomocysteinemia promotes superoxide anion generation and NFkappaB activation in peritoneal macrophages of C57BL/6 mice.
Song YS, Rosenfeld ME., J Med Food 7(2), 2004
PMID: 15298772

RORalpha1 and RORalpha4 suppress TNF-alpha-induced VCAM-1 and ICAM-1 expression in human endothelial cells.
Migita H, Satozawa N, Lin JH, Morser J, Kawai K., FEBS Lett 557(1-3), 2004
PMID: 14741380

Reduced beta3-endonexin levels are associated with enhanced urokinase-type plasminogen activator receptor expression in ApoE-/- mice.
Besta F, Müller I, Lorenz M, Massberg S, Bültmann A, Cabeza N, Richter T, Kremmer E, Nothdurfter C, Brand K, Gawaz M., Thromb Res 114(4), 2004
PMID: 15381392

Statins in hypertensive patients: potential explanations for the ASCOT-LLA study results.
Blanco-Colio LM, Osende JI, Martín-Ventura JL, Tuñón J, Egido J., Drugs 64 Suppl 2(), 2004
PMID: 15765891

Angiopoietin 2 induces cell cycle arrest in endothelial cells: a possible mechanism involved in advanced plaque neovascularization.
Calvi C, Dentelli P, Pagano M, Rosso A, Pegoraro M, Giunti S, Garbarino G, Camussi G, Pegoraro L, Brizzi MF., Arterioscler Thromb Vasc Biol 24(3), 2004
PMID: 14726409

NF-kappaB activation and Fas ligand overexpression in blood and plaques of patients with carotid atherosclerosis: potential implication in plaque instability.
Martín-Ventura JL, Blanco-Colio LM, Muñoz-García B, Gómez-Hernández A, Arribas A, Ortega L, Tuñón J, Egido J., Stroke 35(2), 2004
PMID: 14739407

Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta.
Passerini AG, Polacek DC, Shi C, Francesco NM, Manduchi E, Grant GR, Pritchard WF, Powell S, Chang GY, Stoeckert CJ, Davies PF., Proc Natl Acad Sci U S A 101(8), 2004
PMID: 14983035

Rev-erbalpha upregulates NF-kappaB-responsive genes in vascular smooth muscle cells.
Migita H, Morser J, Kawai K., FEBS Lett 561(1-3), 2004
PMID: 15013753

Strategy for Prevention of Restenosis after PTA. Clinical and Basic Approaches.
Yoshimura S, Kaku Y, Kokuzawa J, Hayashi K, Sakai N., Interv Neuroradiol 10 Suppl 1(), 2004
PMID: 20587274

Mild hyperhomocysteinemia induced by feeding rats diets rich in methionine or deficient in folate promotes early atherosclerotic inflammatory processes.
Zhang R, Ma J, Xia M, Zhu H, Ling W., J Nutr 134(4), 2004
PMID: 15051832

Beyond the endothelium: NF-kappaB regulation of smooth muscle function.
Raines EW, Garton KJ, Ferri N., Circ Res 94(6), 2004
PMID: 15059939

Acetylsalicylic acid inhibits monocyte adhesion to endothelial cells by an antioxidative mechanism.
Eisele G, Schwedhelm E, Schieffer B, Tsikas D, Böger RH., J Cardiovasc Pharmacol 43(4), 2004
PMID: 15085062

Hyperhomocysteinemia activates NF-kappaB and inducible nitric oxide synthase in the kidney.
Zhang F, Siow YL, O K., Kidney Int 65(4), 2004
PMID: 15086472

Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis.
Monaco C, Andreakos E, Kiriakidis S, Mauri C, Bicknell C, Foxwell B, Cheshire N, Paleolog E, Feldmann M., Proc Natl Acad Sci U S A 101(15), 2004
PMID: 15064395

Activation of the NF-kappaB pathway in human cytomegalovirus-infected cells is necessary for efficient transactivation of the major immediate-early promoter.
DeMeritt IB, Milford LE, Yurochko AD., J Virol 78(9), 2004
PMID: 15078930

Flavones mitigate tumor necrosis factor-alpha-induced adhesion molecule upregulation in cultured human endothelial cells: role of nuclear factor-kappa B.
Choi JS, Choi YJ, Park SH, Kang JS, Kang YH., J Nutr 134(5), 2004
PMID: 15113938

Balance between PGD synthase and PGE synthase is a major determinant of atherosclerotic plaque instability in humans.
Cipollone F, Fazia M, Iezzi A, Ciabattoni G, Pini B, Cuccurullo C, Ucchino S, Spigonardo F, De Luca M, Prontera C, Chiarelli F, Cuccurullo F, Mezzetti A., Arterioscler Thromb Vasc Biol 24(7), 2004
PMID: 15155382

In vitro study of the potential role of guanidines in leukocyte functions related to atherogenesis and infection.
Glorieux GL, Dhondt AW, Jacobs P, Van Langeraert J, Lameire NH, De Deyn PP, Vanholder RC., Kidney Int 65(6), 2004
PMID: 15149331

Cardiovascular effects of milk enriched with omega-3 polyunsaturated fatty acids, oleic acid, folic acid, and vitamins E and B6 in volunteers with mild hyperlipidemia.
Carrero JJ, Baró L, Fonollá J, González-Santiago M, Martínez-Férez A, Castillo R, Jiménez J, Boza JJ, López-Huertas E., Nutrition 20(6), 2004
PMID: 15165614

Dual role of oxidized LDL on the NF-kappaB signaling pathway.
Robbesyn F, Salvayre R, Negre-Salvayre A., Free Radic Res 38(6), 2004
PMID: 15346645

Activation of nuclear factor-kappaB and correlation with elevated plasma c-reactive protein in patients with unstable angina.
Li JJ, Fang CH, Chen MZ, Chen X, Lee SW., Heart Lung Circ 13(2), 2004
PMID: 16352190

Wine polyphenols and promotion of cardiac health.
Cooper KA, Chopra M, Thurnham DI., Nutrition research reviews. 17(1), 2004
PMID: IND43648761

Nuclear factor-kappaB: its role in health and disease.
Kumar A, Takada Y, Boriek AM, Aggarwal BB., J Mol Med (Berl) 82(7), 2004
PMID: 15175863

Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice.
Zhou J, Werstuck GH, Lhoták S, de Koning AB, Sood SK, Hossain GS, Møller J, Ritskes-Hoitinga M, Falk E, Dayal S, Lentz SR, Austin RC., Circulation 110(2), 2004
PMID: 15210586

Selenium supplementation decreases nuclear factor-kappa B activity in peripheral blood mononuclear cells from type 2 diabetic patients.
Faure P, Ramon O, Favier A, Halimi S., Eur J Clin Invest 34(7), 2004
PMID: 15255784

Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase expression by a novel compound, mercaptopyrazine, through suppression of nuclear factor-kappaB binding to DNA.
Lim S, Kang KW, Park SY, Kim SI, Choi YS, Kim ND, Lee KU, Lee HK, Pak YK., Biochem Pharmacol 68(4), 2004
PMID: 15276079

Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis.
Shishodia S, Aggarwal BB., J Biol Chem 279(45), 2004
PMID: 15322087

More fibrosis and thrombotic complications but similar expression patterns of markers for coagulation and inflammation in symptomatic plaques from DM2 patients.
Sommeijer DW, Beganovic A, Schalkwijk CG, Ploegmakers H, van der Loos CM, van Aken BE, ten Cate H, van der Wal AC., J Histochem Cytochem 52(9), 2004
PMID: 15314081

MAPK-dependent regulation of IL-1- and beta-adrenoreceptor-induced inflammatory cytokine production from mast cells: implications for the stress response.
Chi DS, Fitzgerald SM, Pitts S, Cantor K, King E, Lee SA, Huang SK, Krishnaswamy G., BMC Immunol 5(), 2004
PMID: 15383152

Role of oxidative modifications in atherosclerosis.
Stocker R, Keaney JF., Physiol Rev 84(4), 2004
PMID: 15383655

Interleukin-10 attenuates the response to vascular injury.
Zimmerman MA, Reznikov LL, Raeburn CD, Selzman CH., J Surg Res 121(2), 2004
PMID: 15501460

Linking oxidative stress and inflammation in kidney disease: which is the chicken and which is the egg?
Himmelfarb J., Semin Dial 17(6), 2004
PMID: 15660575

Butter and walnuts, but not olive oil, elicit postprandial activation of nuclear transcription factor kappaB in peripheral blood mononuclear cells from healthy men.
Bellido C, López-Miranda J, Blanco-Colio LM, Pérez-Martínez P, Muriana FJ, Martín-Ventura JL, Marín C, Gómez P, Fuentes F, Egido J, Pérez-Jiménez F., Am J Clin Nutr 80(6), 2004
PMID: 15585759

Anti-inflammatory and immunomodulatory effects of statins.
Blanco-Colio LM, Tuñón J, Martín-Ventura JL, Egido J., Kidney Int 63(1), 2003
PMID: 12472764

Patterns of oxidized epitopes, but not NF-kappa B expression, change during atherogenesis in WHHL rabbits.
Bräsen JH, Häkkinen T, Malle E, Beisiegel U, Ylä-Herttuala S., Atherosclerosis 166(1), 2003
PMID: 12482546

Delayed treatment with MLN519 reduces infarction and associated neurologic deficit caused by focal ischemic brain injury in rats via antiinflammatory mechanisms involving nuclear factor-kappaB activation, gliosis, and leukocyte infiltration.
Williams AJ, Hale SL, Moffett JR, Dave JR, Elliott PJ, Adams J, Tortella FC., J Cereb Blood Flow Metab 23(1), 2003
PMID: 12500093

Regulation of nuclear translocation of nuclear factor-kappaB relA: evidence for complex dynamics at the single-cell level.
Schooley K, Zhu P, Dower SK, Qwarnström EE., Biochem J 369(pt 2), 2003
PMID: 12350227

HMG-CoA reductase inhibitors regulate inflammatory transcription factors in human endothelial and vascular smooth muscle cells.
Dichtl W, Dulak J, Frick M, Alber HF, Schwarzacher SP, Ares MP, Nilsson J, Pachinger O, Weidinger F., Arterioscler Thromb Vasc Biol 23(1), 2003
PMID: 12524225

Effect of the proteasome inhibitor MLN519 on the expression of inflammatory molecules following middle cerebral artery occlusion and reperfusion in the rat.
Berti R, Williams AJ, Velarde LC, Moffett JR, Elliott PJ, Adams J, Yao C, Dave JR, Tortella FC., Neurotox Res 5(7), 2003
PMID: 14715434

Involvement of transcription factors in plasma HDL protection against TNF-alpha-induced vascular cell adhesion molecule-1 expression.
Park SH, Park JH, Kang JS, Kang YH., Int J Biochem Cell Biol 35(2), 2003
PMID: 12479867

Inhibition of NFkappaB activation using cis-element 'decoy' of NFkappaB binding site reduces neointimal formation in porcine balloon-injured coronary artery model.
Yamasaki K, Asai T, Shimizu M, Aoki M, Hashiya N, Sakonjo H, Makino H, Kaneda Y, Ogihara T, Morishita R., Gene Ther 10(4), 2003
PMID: 12595894

Light-induced photoreceptor degeneration may involve the NF kappa B/caspase-1 pathway in vivo.
Wu T, Chiang SK, Chau FY, Tso MO., Brain Res 967(1-2), 2003
PMID: 12650962

Redox regulation following cardiac ischemia and reperfusion.
Marczin N, Bundy RE, Hoare GS, Yacoub M., Coron Artery Dis 14(2), 2003
PMID: 12655276

Interactions between inflammation, oxidative stress, and endothelial dysfunction in end-stage renal disease.
Stenvinkel P., J Ren Nutr 13(2), 2003
PMID: 12671839

Transcriptional inhibition of interleukin-8 expression in tumor necrosis factor-tolerant cells: evidence for involvement of C/EBP beta.
Weber M, Sydlik C, Quirling M, Nothdurfter C, Zwergal A, Heiss P, Bell S, Neumeier D, Ziegler-Heitbrock HW, Brand K., J Biol Chem 278(26), 2003
PMID: 12707271

Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans.
Bruun JM, Lihn AS, Verdich C, Pedersen SB, Toubro S, Astrup A, Richelsen B., Am J Physiol Endocrinol Metab 285(3), 2003
PMID: 12736161

Activated platelets trigger an inflammatory response and enhance migration of aortic smooth muscle cells.
Massberg S, Vogt F, Dickfeld T, Brand K, Page S, Gawaz M., Thromb Res 110(4), 2003
PMID: 14512080

Engineering the response to vascular injury: divergent effects of deregulated E2F1 expression on vascular smooth muscle cells and endothelial cells result in endothelial recovery and inhibition of neointimal growth.
Goukassian DA, Kishore R, Krasinski K, Dolan C, Luedemann C, Yoon YS, Kearney M, Hanley A, Ma H, Asahara T, Isner JM, Losordo DW., Circ Res 93(2), 2003
PMID: 12829616

Garlic (Allium sativum L.) modulates cytokine expression in lipopolysaccharide-activated human blood thereby inhibiting NF-kappaB activity.
Keiss HP, Dirsch VM, Hartung T, Haffner T, Trueman L, Auger J, Kahane R, Vollmar AM., J Nutr 133(7), 2003
PMID: 12840173

Hematein inhibits atherosclerosis by inhibition of reactive oxygen generation and NF-kappaB-dependent inflammatory mediators in hyperlipidemic mice.
Choi JH, Jeong TS, Kim DY, Kim YM, Na HJ, Nam KH, Lee SB, Kim HC, Oh SR, Choi YK, Bok SH, Oh GT., J Cardiovasc Pharmacol 42(2), 2003
PMID: 12883334

The receptor RAGE as a progression factor amplifying arachidonate-dependent inflammatory and proteolytic response in human atherosclerotic plaques: role of glycemic control.
Cipollone F, Iezzi A, Fazia M, Zucchelli M, Pini B, Cuccurullo C, De Cesare D, De Blasis G, Muraro R, Bei R, Chiarelli F, Schmidt AM, Cuccurullo F, Mezzetti A., Circulation 108(9), 2003
PMID: 12912808

Dietary cholate is required for antiatherogenic effects of ethanol in mouse models.
Deeg MA., Alcohol Clin Exp Res 27(9), 2003
PMID: 14506412

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.
Kanters E, Pasparakis M, Gijbels MJ, Vergouwe MN, Partouns-Hendriks I, Fijneman RJ, Clausen BE, Förster I, Kockx MM, Rajewsky K, Kraal G, Hofker MH, de Winther MP., J Clin Invest 112(8), 2003
PMID: 14561702

[Role of coronary risk factors in blood thrombogenicity and acute coronary syndromes].
Sambola A, Fuster V, Badimon JJ., Rev Esp Cardiol 56(10), 2003
PMID: 14563295

Clinical implications of matrix metalloproteinases.
Mandal M, Mandal A, Das S, Chakraborti T, Sajal C., Mol Cell Biochem 252(1-2), 2003
PMID: 14577606

Celiprolol activates eNOS through the PI3K-Akt pathway and inhibits VCAM-1 Via NF-kappaB induced by oxidative stress.
Kobayashi N, Mita S, Yoshida K, Honda T, Kobayashi T, Hara K, Nakano S, Tsubokou Y, Matsuoka H., Hypertension 42(5), 2003
PMID: 14557279

Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.
Ameziane N, Beillat T, Verpillat P, Chollet-Martin S, Aumont MC, Seknadji P, Lamotte M, Lebret D, Ollivier V, de Prost D., Arterioscler Thromb Vasc Biol 23(12), 2003
PMID: 14563652

Inflammation meets oxidation: NF-kappaB as a mediator of initial lesion development in atherosclerosis.
Kutuk O, Basaga H., Trends Mol Med 9(12), 2003
PMID: 14659470

Mechanisms involved in the stimulatory effect of advanced glycation end products on growth of rat aortic smooth muscle cells.
Seki N, Hashimoto N, Sano H, Horiuchi S, Yagui K, Makino H, Saito Y., Metabolism 52(12), 2003
PMID: 14669155

C-reactive protein activates the nuclear factor-kappaB signal transduction pathway in saphenous vein endothelial cells: implications for atherosclerosis and restenosis.
Verma S, Badiwala MV, Weisel RD, Li SH, Wang CH, Fedak PW, Li RK, Mickle DA., J Thorac Cardiovasc Surg 126(6), 2003
PMID: 14688701

The role of estrogen in cardiovascular disease.
Baker L, Meldrum KK, Wang M, Sankula R, Vanam R, Raiesdana A, Tsai B, Hile K, Brown JW, Meldrum DR., J Surg Res 115(2), 2003
PMID: 14697301

Unsaturated fatty acids selectively induce an inflammatory environment in human endothelial cells.
Toborek M, Lee YW, Garrido R, Kaiser S, Hennig B., Am J Clin Nutr 75(1), 2002
PMID: 11756069

Nuclear factor-kappaB immunoreactivity is present in human coronary plaque and enhanced in patients with unstable angina pectoris.
Wilson SH, Best PJ, Edwards WD, Holmes DR, Carlson PJ, Celermajer DS, Lerman A., Atherosclerosis 160(1), 2002
PMID: 11755932

An IkappaB-alpha mutant inhibits cytokine gene expression and proliferation in human vascular smooth muscle cells.
Wang Z, Castresana MR, Detmer K, Newman WH., J Surg Res 102(2), 2002
PMID: 11796019

Modulation of inflammatory mediators and PPARgamma and NFkappaB expression by pravastatin in response to lipoproteins in human monocytes in vitro.
Zelvyte I, Dominaitiene R, Crisby M, Janciauskiene S., Pharmacol Res 45(2), 2002
PMID: 11846628

The potential for novel anti-inflammatory therapies for coronary artery disease.
Cascieri MA., Nat Rev Drug Discov 1(2), 2002
PMID: 12120093

Mechanical stress-induced apoptosis in the cardiovascular system.
Wernig F, Xu Q., Prog Biophys Mol Biol 78(2-3), 2002
PMID: 12429110

Modulation of matrix metalloproteinase-1, its tissue inhibitor, and nuclear factor-kappa B by losartan in hypercholesterolemic rabbits.
Chen H, Li D, Mehta JL., J Cardiovasc Pharmacol 39(3), 2002
PMID: 11862111

The role of oxidative stress in mechanisms of metal-induced carcinogenesis.
Galaris D, Evangelou A., Crit Rev Oncol Hematol 42(1), 2002
PMID: 11923071

Phytochemical inhibition of interleukin-4-activated Stat6 and expression of VCAM-1.
Schnyder B, Schnyder-Candrian S, Panski A, Bömmel H, Heim M, Duschl A, Moser R., Biochem Biophys Res Commun 292(4), 2002
PMID: 11944890

Effect of alcohol on lipids and lipoproteins in relation to atherosclerosis.
Hannuksela ML, Liisanantti MK, Savolainen MJ., Crit Rev Clin Lab Sci 39(3), 2002
PMID: 12120782

Activation of nuclear factor-kappaB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes.
Romeo G, Liu WH, Asnaghi V, Kern TS, Lorenzi M., Diabetes 51(7), 2002
PMID: 12086956

[Interleukin-10 and coronary disease].
Pérez Fernández R, Kaski JC., Rev Esp Cardiol 55(7), 2002
PMID: 12113702

Lack of TNF-alpha attenuates intimal hyperplasia after mouse carotid artery injury.
Zimmerman MA, Selzman CH, Reznikov LL, Miller SA, Raeburn CD, Emmick J, Meng X, Harken AH., Am J Physiol Regul Integr Comp Physiol 283(2), 2002
PMID: 12121864

Induction of IkappaB: atrial natriuretic peptide as a regulator of the NF-kappaB pathway.
Kiemer AK, Weber NC, Vollmar AM., Biochem Biophys Res Commun 295(5), 2002
PMID: 12135603

Vascular inflammation and the renin-angiotensin system.
Brasier AR, Recinos A, Eledrisi MS., Arterioscler Thromb Vasc Biol 22(8), 2002
PMID: 12171785

Hepatocyte growth factor is a survival factor for endothelial cells and is expressed in human atherosclerotic plaques.
Ma H, Calderon TM, Fallon JT, Berman JW., Atherosclerosis 164(1), 2002
PMID: 12119196

Effect of low-dose aspirin on vascular inflammation, plaque stability, and atherogenesis in low-density lipoprotein receptor-deficient mice.
Cyrus T, Sung S, Zhao L, Funk CD, Tang S, Praticò D., Circulation 106(10), 2002
PMID: 12208806

Quantitative real-time RT-PCR analysis of inflammatory gene expression associated with ischemia-reperfusion brain injury.
Berti R, Williams AJ, Moffett JR, Hale SL, Velarde LC, Elliott PJ, Yao C, Dave JR, Tortella FC., J Cereb Blood Flow Metab 22(9), 2002
PMID: 12218412

Increased IkappaB kinase activity is associated with activated NF-kappaB in acute myeloid blasts.
Baumgartner B, Weber M, Quirling M, Fischer C, Page S, Adam M, Von Schilling C, Waterhouse C, Schmid C, Neumeier D, Brand K., Leukemia 16(10), 2002
PMID: 12357358

A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation.
Massberg S, Brand K, Grüner S, Page S, Müller E, Müller I, Bergmeier W, Richter T, Lorenz M, Konrad I, Nieswandt B, Gawaz M., J Exp Med 196(7), 2002
PMID: 12370251

Chlamydia pneumoniae activates IKK/I kappa B-mediated signaling, which is inhibited by 4-HNE and following primary exposure.
Donath B, Fischer C, Page S, Prebeck S, Jilg N, Weber M, da Costa C, Neumeier D, Miethke T, Brand K., Atherosclerosis 165(1), 2002
PMID: 12208473

Molecular inflammation hypothesis of aging based on the anti-aging mechanism of calorie restriction.
Chung HY, Kim HJ, Kim KW, Choi JS, Yu BP., Microsc Res Tech 59(4), 2002
PMID: 12424787

Growth factors enhance interleukin-1 beta-induced persistent activation of nuclear factor-kappa B in rat vascular smooth muscle cells.
Jiang B, Xu S, Brecher P, Cohen RA., Arterioscler Thromb Vasc Biol 22(11), 2002
PMID: 12426209

Regulation of cell signalling by vitamin E.
Rimbach G, Minihane AM, Majewicz J, Fischer A, Pallauf J, Virgli F, Weinberg PD., Proc Nutr Soc 61(4), 2002
PMID: 12691170

Activation of tubular epithelial cells in diabetic nephropathy.
Morcos M, Sayed AA, Bierhaus A, Yard B, Waldherr R, Merz W, Kloeting I, Schleicher E, Mentz S, Abd el Baki RF, Tritschler H, Kasper M, Schwenger V, Hamann A, Dugi KA, Schmidt AM, Stern D, Ziegler R, Haering HU, Andrassy M, van der Woude F, Nawroth PP., Diabetes 51(12), 2002
PMID: 12453911

Suppression of cyclooxygenase-2 and inducible nitric oxide synthase expression by conjugated linoleic acid in murine macrophages.
Iwakiri Y, Sampson DA, Allen KG., Prostaglandins Leukot Essent Fatty Acids 67(6), 2002
PMID: 12468265

Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression.
Tzima E, Del Pozo MA, Kiosses WB, Mohamed SA, Li S, Chien S, Schwartz MA., EMBO J 21(24), 2002
PMID: 12486000

Series introduction: the transcription factor NF-kappaB and human disease.
Baldwin AS., J Clin Invest 107(1), 2001
PMID: 11134170

The smooth muscle cell membrane during atherogenesis: a potential target for amlodipine in atheroprotection.
Tulenko TN, Sumner AE, Chen M, Huang Y, Laury-Kleintop L, Ferdinand FD., Am Heart J 141(2 suppl), 2001
PMID: 11174352

Homocysteine inhibits TNF-alpha-induced endothelial adhesion molecule expression and monocyte adhesion via nuclear factor-kappaB dependent pathway.
Stangl V, Günther C, Jarrin A, Bramlage P, Moobed M, Staudt A, Baumann G, Stangl K, Felix SB., Biochem Biophys Res Commun 280(4), 2001
PMID: 11162639

NF-kappaB: pivotal mediator or innocent bystander in atherogenesis?
Collins T, Cybulsky MI., J Clin Invest 107(3), 2001
PMID: 11160146

The effect of alpha-tocopherol on monocyte proatherogenic activity.
Jialal I, Devaraj S, Kaul N., J Nutr 131(2), 2001
PMID: 11160567

Activation of the transcription factors nuclear factor-kappaB and activator protein-1 in bladder smooth muscle exposed to outlet obstruction and mechanical stretching.
Persson K, Dean-Mckinney T, Steers WD, Tuttle JB., J Urol 165(2), 2001
PMID: 11176450

Transcription factor-kappa B (NF-kappa B) and renal disease.
Guijarro C, Egido J., Kidney Int 59(2), 2001
PMID: 11168923

[Cellular and molecular biology of atherosclerotic lesions]
Martínez-González J, Llorente-Cortés V, Badimon L., Rev Esp Cardiol 54(2), 2001
PMID: 11181311

Bacterial lipopolysaccharide and tumor necrosis factor alpha synergistically increase expression of human endothelial adhesion molecules through activation of NF-kappaB and p38 mitogen-activated protein kinase signaling pathways.
Jersmann HP, Hii CS, Ferrante JV, Ferrante A., Infect Immun 69(3), 2001
PMID: 11179288

Therapeutic potential of dietary phase 2 enzyme inducers in ameliorating diseases that have an underlying inflammatory component.
Juurlink BH., Can J Physiol Pharmacol 79(3), 2001
PMID: 11294604

Peroxisome proliferator-activated receptors in atherosclerosis and inflammation--an update.
Elangbam CS, Tyler RD, Lightfoot RM., Toxicol Pathol 29(2), 2001
PMID: 11421489

Inhibition of cytokine-induced vascular cell adhesion molecule-1 expression; possible mechanism for anti-atherogenic effect of Agastache rugosa.
Hong JJ, Choi JH, Oh SR, Lee HK, Park JH, Lee KY, Kim JJ, Jeong TS, Oh GT., FEBS Lett 495(3), 2001
PMID: 11334881

High-energy diets, fatty acids and endothelial cell function: implications for atherosclerosis.
Hennig B, Toborek M, McClain CJ., J Am Coll Nutr 20(2 suppl), 2001
PMID: 11349944

The role of apoptotic cell death in cardiovascular disease.
McLaughlin R, Kelly CJ, Kay E, Bouchier-Hayes D., Ir J Med Sci 170(2), 2001
PMID: 11491050

Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors.
Ruiz-Ortega M, Ruiz-Ortega M, Lorenzo O, Rupérez M, Blanco J, Egido J., Am J Pathol 158(5), 2001
PMID: 11337372

Homocysteine induces monocyte chemoattractant protein-1 expression by activating NF-kappaB in THP-1 macrophages.
Wang G, Siow YL, O K., Am J Physiol Heart Circ Physiol 280(6), 2001
PMID: 11356643

Oxidized LDL-mediated monocyte adhesion to endothelial cells does not involve NFkappaB.
Dwivedi A, Anggård EE, Carrier MJ., Biochem Biophys Res Commun 284(1), 2001
PMID: 11374896

Cryptosporidium parvum activates nuclear factor kappaB in biliary epithelia preventing epithelial cell apoptosis.
Chen XM, Levine SA, Splinter PL, Tietz PS, Ganong AL, Jobin C, Gores GJ, Paya CV, LaRusso NF., Gastroenterology 120(7), 2001
PMID: 11375958

Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice.
Kislinger T, Tanji N, Wendt T, Qu W, Lu Y, Ferran LJ, Taguchi A, Olson K, Bucciarelli L, Goova M, Hofmann MA, Cataldegirmen G, D'Agati V, Pischetsrieder M, Stern DM, Schmidt AM., Arterioscler Thromb Vasc Biol 21(6), 2001
PMID: 11397695

Therapeutic implications of inflammation in atherosclerotic cardiovascular disease.
Selzman CH, Miller SA, Harken AH., Ann Thorac Surg 71(6), 2001
PMID: 11426810

4-hydroxynonenal prevents NO production in vascular smooth muscle cells by inhibiting nuclear factor-kappaB-dependent transcriptional activation of inducible NO synthase.
Hattori Y, Hattori S, Kasai K., Arterioscler Thromb Vasc Biol 21(7), 2001
PMID: 11451748

Effects of conjugated linoleic acids and docosahexaenoic acid on rat liver and reproductive tissue fatty acids, prostaglandins and matrix metalloproteinase production.
Harris MA, Hansen RA, Vidsudhiphan P, Koslo JL, Thomas JB, Watkins BA, Allen KG., Prostaglandins Leukot Essent Fatty Acids 65(1), 2001
PMID: 11487304

Nuclear factor kappa-B and the heart.
Valen G, Yan ZQ, Hansson GK., J Am Coll Cardiol 38(2), 2001
PMID: 11499717

Different effects of antisense RelA p65 and NF-kappaB1 p50 oligonucleotides on the nuclear factor-kappaB mediated expression of ICAM-1 in human coronary endothelial and smooth muscle cells.
Voisard R, Huber N, Baur R, Susa M, Ickrath O, Both A, Koenig W, Hombach V., BMC Mol Biol 2(), 2001
PMID: 11532196

25-hydroxycholesterol induces lipopolysaccharide-tolerance and decreases a lipopolysaccharide-induced TNF-alpha secretion in macrophages.
Englund MC, Karlsson AL, Wiklund O, Bondjers G, Ohlsson BG., Atherosclerosis 158(1), 2001
PMID: 11500175

The effect of endothelin-1 on nuclear factor kappa B in macrophages.
Wilson SH, Simari RD, Lerman A., Biochem Biophys Res Commun 286(5), 2001
PMID: 11527395

Serum neopterin and activity of coronary artery disease.
Auer J, Berent R, Labetanig E, Eber B., Heart Dis 3(5), 2001
PMID: 11975809

Reciprocal antagonism between estrogen receptor and NF-kappaB activity in vivo.
Evans MJ, Eckert A, Lai K, Adelman SJ, Harnish DC., Circ Res 89(9), 2001
PMID: 11679413

Molecular aspects of lipoic acid in the prevention of diabetes complications.
Packer L, Kraemer K, Rimbach G., Nutrition 17(10), 2001
PMID: 11684397

Selected contribution: estrogen receptor-alpha gene transfer inhibits proliferation and NF-kappaB activation in VSM cells from female rats.
Sharma RV, Gurjar MV, Bhalla RC., J Appl Physiol (1985) 91(5), 2001
PMID: 11641387

Inhibition of intimal hyperplasia after balloon injury in rat carotid artery model using cis-element 'decoy' of nuclear factor-kappaB binding site as a novel molecular strategy.
Yoshimura S, Morishita R, Hayashi K, Yamamoto K, Nakagami H, Kaneda Y, Sakai N, Ogihara T., Gene Ther 8(21), 2001
PMID: 11895002

Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB.
Bierhaus A, Schiekofer S, Schwaninger M, Andrassy M, Humpert PM, Chen J, Hong M, Luther T, Henle T, Klöting I, Morcos M, Hofmann M, Tritschler H, Weigle B, Kasper M, Smith M, Perry G, Schmidt AM, Stern DM, Häring HU, Schleicher E, Nawroth PP., Diabetes 50(12), 2001
PMID: 11723063

Persistent activation of nuclear factor-kappaB by interleukin-1beta and subsequent inducible NO synthase expression requires extracellular signal-regulated kinase.
Jiang B, Brecher P, Cohen RA., Arterioscler Thromb Vasc Biol 21(12), 2001
PMID: 11742864

Cholesterol enrichment upregulates intercellular adhesion molecule-1 in human vascular endothelial cells.
Yuan Y, Verna LK, Wang NP, Liao HL, Ma KS, Wang Y, Zhu Y, Stemerman MB., Biochim Biophys Acta 1534(2-3), 2001
PMID: 11786300

Role of nuclear factor-kappa B (NF-kappa B) in inflammation, periodontitis, and atherogenesis.
Nichols TC, Fischer TH, Deliargyris EN, Baldwin AS., Ann Periodontol 6(1), 2001
PMID: 11887466

Activated nuclear factor-kappaB is present in the coronary vasculature in experimental hypercholesterolemia.
Wilson SH, Caplice NM, Simari RD, Holmes DR, Carlson PJ, Lerman A., Atherosclerosis 148(1), 2000
PMID: 10580167

Platelets induce alterations of chemotactic and adhesive properties of endothelial cells mediated through an interleukin-1-dependent mechanism. Implications for atherogenesis.
Gawaz M, Brand K, Dickfeld T, Pogatsa-Murray G, Page S, Bogner C, Koch W, Schömig A, Neumann F., Atherosclerosis 148(1), 2000
PMID: 10580173

NF-kappaB inhibition ameliorates angiotensin II-induced inflammatory damage in rats.
Muller DN, Dechend R, Mervaala EM, Park JK, Schmidt F, Fiebeler A, Theuer J, Breu V, Ganten D, Haller H, Luft FC., Hypertension 35(1 pt 2), 2000
PMID: 10642297

Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes.
Mervaala E, Müller DN, Park JK, Dechend R, Schmidt F, Fiebeler A, Bieringer M, Breu V, Ganten D, Haller H, Luft FC., Hypertension 35(1 pt 2), 2000
PMID: 10642325

The endothelium in atherogenesis.
Hunt BJ., Lupus 9(3), 2000
PMID: 10805486

Angiotensin-converting enzyme inhibitors downregulate tissue factor synthesis in monocytes.
Napoleone E, Di Santo A, Camera M, Tremoli E, Lorenzet R., Circ Res 86(2), 2000
PMID: 10666408

Adhesion of monocyte very late antigen-4 to endothelial vascular cell adhesion molecule-1 induces interleukin-1beta-dependent expression of interleukin-6 in endothelial cells.
Zohlnhöfer D, Brand K, Schipek K, Pogatsa-Murray G, Schömig A, Neumann FJ., Arterioscler Thromb Vasc Biol 20(2), 2000
PMID: 10669630

Alpha-phenyl-tert-butylnitrone (PBN) inhibits NFkappaB activation offering protection against chemically induced diabetes.
Ho E, Chen G, Bray TM., Free Radic Biol Med 28(4), 2000
PMID: 10719242

Increased serum neopterin: a marker of coronary artery disease activity in women.
Garcia-Moll X, Cole D, Zouridakis E, Kaski JC., Heart 83(3), 2000
PMID: 10677418

Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress.
Pueyo ME, Gonzalez W, Nicoletti A, Savoie F, Arnal JF, Michel JB., Arterioscler Thromb Vasc Biol 20(3), 2000
PMID: 10712386

Nuclear factor-kappa B activity and intestinal inflammation in dextran sulphate sodium (DSS)-induced colitis in mice is suppressed by gliotoxin.
Herfarth H, Brand K, Rath HC, Rogler G, Schölmerich J, Falk W., Clin Exp Immunol 120(1), 2000
PMID: 10759764

Induction of signal transduction pathways in rat gastric epithelial cells stimulated with interleukin-1beta.
Tominaga K, Higuchi K, Tsuno M, Watanabe T, Fujiwara Y, Kim S, Arakawa T, Iwao H, Kuroki T., Aliment Pharmacol Ther 14 Suppl 1(), 2000
PMID: 10807411

Macrophages stimulated with IFN-gamma activate NF-kappa B and induce MCP-1 gene expression in primary human endothelial cells.
Rimbach G, Valacchi G, Canali R, Virgili F., Mol Cell Biol Res Commun 3(4), 2000
PMID: 10891398

Chlamydia pneumoniae activates nuclear factor kappaB and activator protein 1 in human vascular smooth muscle and induces cellular proliferation.
Miller SA, Selzman CH, Shames BD, Barton HA, Johnson SM, Harken AH., J Surg Res 90(1), 2000
PMID: 10781378

Activation of nuclear factor-kB in the spinal cord of experimental allergic encephalomyelitis.
Pahan K, Schmid M., Neurosci Lett 287(1), 2000
PMID: 10841980

Essential roles of IkappaB kinases alpha and beta in serum- and IL-1-induced human VSMC proliferation.
Sasu S, Beasley D., Am J Physiol Heart Circ Physiol 278(6), 2000
PMID: 10843878

Pathogenesis of liver fibrosis: role of oxidative stress.
Poli G., Mol Aspects Med 21(3), 2000
PMID: 10978499

Antiphospholipid antibodies and the endothelium.
Hunt BJ, Khamashta MA., Curr Rheumatol Rep 2(3), 2000
PMID: 11123067

The carboxyl-terminal fragment of alpha1-antitrypsin is present in atherosclerotic plaques and regulates inflammatory transcription factors in primary human monocytes.
Dichtl W, Moraga F, Ares MP, Crisby M, Nilsson J, Lindgren S, Janciauskiene S., Mol Cell Biol Res Commun 4(1), 2000
PMID: 11152628

The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation.
Hajra L, Evans AI, Chen M, Hyduk SJ, Collins T, Cybulsky MI., Proc Natl Acad Sci U S A 97(16), 2000
PMID: 10922059

Red wine intake prevents nuclear factor-kappaB activation in peripheral blood mononuclear cells of healthy volunteers during postprandial lipemia.
Blanco-Colio LM, Valderrama M, Alvarez-Sala LA, Bustos C, Ortego M, Hernández-Presa MA, Cancelas P, Gómez-Gerique J, Millán J, Egido J., Circulation 102(9), 2000
PMID: 10961967

Effects of alpha-tocopherol on ox-LDL-mediated degradation of IkappaB and apoptosis in cultured human coronary artery endothelial cells.
Li D, Saldeen T, Mehta JL., J Cardiovasc Pharmacol 36(3), 2000
PMID: 10975585

Role of endocytosis in the transactivation of nuclear factor-kappaB by oxidized low-density lipoprotein.
Han CY, Park SY, Pak YK., Biochem J 350 Pt 3(), 2000
PMID: 10970799

Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway.
Ouchi N, Kihara S, Arita Y, Okamoto Y, Maeda K, Kuriyama H, Hotta K, Nishida M, Takahashi M, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Funahashi T, Matsuzawa Y., Circulation 102(11), 2000
PMID: 10982546

Angiotensin II induces gene transcription through cell-type-dependent effects on the nuclear factor-kappaB (NF-kappaB) transcription factor.
Brasier AR, Jamaluddin M, Han Y, Patterson C, Runge MS., Mol Cell Biochem 212(1-2), 2000
PMID: 11108147

Overexpression of truncated IkappaBalpha induces TNF-alpha-dependent apoptosis in human vascular smooth muscle cells.
Obara H, Takayanagi A, Hirahashi J, Tanaka K, Wakabayashi G, Matsumoto K, Shimazu M, Shimizu N, Kitajima M., Arterioscler Thromb Vasc Biol 20(10), 2000
PMID: 11031204

Inhibition of vascular smooth muscle cell proliferation by sodium salicylate mediated by upregulation of p21(Waf1) and p27(Kip1).
Marra DE, Simoncini T, Liao JK., Circulation 102(17), 2000
PMID: 11044431

Implication of NF-kappaB in Helicobacter pylori-associated gastritis.
Isomoto H, Mizuta Y, Miyazaki M, Takeshima F, Omagari K, Murase K, Nishiyama T, Inoue K, Murata I, Kohno S., Am J Gastroenterol 95(10), 2000
PMID: 11051346

Hyperinsulinemia and vascular dysfunction: the role of nuclear factor-kappaB, yet again.
Schmidt AM, Stern DM., Circ Res 87(9), 2000
PMID: 11055972

Serotonin increases interleukin-6 synthesis in human vascular smooth muscle cells.
Ito T, Ikeda U, Shimpo M, Yamamoto K, Shimada K., Circulation 102(20), 2000
PMID: 11076827

NF-kappaB activation in response to toxical and therapeutical agents: role in inflammation and cancer treatment.
Bours V, Bonizzi G, Bentires-Alj M, Bureau F, Piette J, Lekeux P, Merville M., Toxicology 153(1-3), 2000
PMID: 11090945

Homocysteine stimulates nuclear factor kappaB activity and monocyte chemoattractant protein-1 expression in vascular smooth-muscle cells: a possible role for protein kinase C.
Wang G, Siow YL, O K., Biochem J 352 Pt 3(), 2000
PMID: 11104691

Pravastatin down-regulates inflammatory mediators in human monocytes in vitro.
Grip O, Janciauskiene S, Lindgren S., Eur J Pharmacol 410(1), 2000
PMID: 11134659

Nuclear factor-kappaB transcription factor decoy treatment inhibits graft coronary artery disease after cardiac transplantation in rodents.
Feeley BT, Miniati DN, Park AK, Hoyt EG, Robbins RC., Transplantation 70(11), 2000
PMID: 11152216

A role for reduced coenzyme Q in atherosclerosis?
Thomas SR, Witting PK, Stocker R., Biofactors 9(2-4), 1999
PMID: 10416033

High expression of human 15-lipoxygenase induces NF-kappaB-mediated expression of vascular cell adhesion molecule 1, intercellular adhesion molecule 1, and T-cell adhesion on human endothelial cells.
Viita H, Sen CK, Roy S, Siljamäki T, Nikkari T, Ylä-Herttuala S., Antioxid Redox Signal 1(1), 1999
PMID: 11225735

Adenovirus-mediated gene transfer is augmented in basilar and carotid arteries of heritable hyperlipidemic rabbits.
Lund DD, Faraci FM, Ooboshi H, Davidson BL, Heistad DD., Stroke 30(1), 1999
PMID: 9880399

Mildly oxidized low-density lipoproteins decrease early production of interleukin 2 and nuclear factor kappaB binding to DNA in activated T-lymphocytes.
Caspar-Bauguil S, Tkaczuk J, Haure MJ, Durand M, Alcouffe J, Thomsen M, Salvayre R, Benoist H., Biochem J 337 ( Pt 2)(), 1999
PMID: 9882624

Serial analysis of gene expression to assess the endothelial cell response to an atherogenic stimulus.
de Waard V, van den Berg BM, Veken J, Schultz-Heienbrok R, Pannekoek H, van Zonneveld AJ., Gene 226(1), 1999
PMID: 9889296

A novel function for A20 in smooth muscle cells: inhibition of activation and proliferation.
Arvelo MB, Badrichani AZ, Stroka DM, Grey ST, Bach FH, Ferran C., Transplant Proc 31(1-2), 1999
PMID: 10083374

Nuclear factor-kappa B regulates induction of apoptosis and inhibitor of apoptosis protein-1 expression in vascular smooth muscle cells.
Erl W, Hansson GK, de Martin R, Draude G, Weber KS, Weber C., Circ Res 84(6), 1999
PMID: 10189354

Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-kappa B transcription factors.
Han Y, Runge MS, Brasier AR., Circ Res 84(6), 1999
PMID: 10189357

Very low-density lipoprotein activates nuclear factor-kappaB in endothelial cells.
Dichtl W, Nilsson L, Goncalves I, Ares MP, Banfi C, Calara F, Hamsten A, Eriksson P, Nilsson J., Circ Res 84(9), 1999
PMID: 10325246

gamma-tocopherol decreases ox-LDL-mediated activation of nuclear factor-kappaB and apoptosis in human coronary artery endothelial cells.
Li D, Saldeen T, Mehta JL., Biochem Biophys Res Commun 259(1), 1999
PMID: 10334932

The NFkappaB inhibitory peptide, IkappaBalpha, prevents human vascular smooth muscle proliferation.
Selzman CH, Shames BD, McIntyre RC, Banerjee A, Harken AH., Ann Thorac Surg 67(5), 1999
PMID: 10355388

Gallates inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of leukocyte adhesion molecules in vascular endothelial cells.
Murase T, Kume N, Hase T, Shibuya Y, Nishizawa Y, Tokimitsu I, Kita T., Arterioscler Thromb Vasc Biol 19(6), 1999
PMID: 10364071

Involvement of nuclear factor-kappaB in a murine model for the acute form of autoimmune-like toxic oil syndrome.
Bell SA, Page S, Baumgartner B, Berking C, Haas M, Eisele T, Neumeier D, Brand K., Toxicol Appl Pharmacol 157(3), 1999
PMID: 10373405

Angiotensin induces inflammatory activation of human vascular smooth muscle cells.
Kranzhöfer R, Schmidt J, Pfeiffer CA, Hagl S, Libby P, Kübler W., Arterioscler Thromb Vasc Biol 19(7), 1999
PMID: 10397679

Triglyceride-rich lipoproteins: are links with atherosclerosis mediated by a procoagulant and proinflammatory phenotype?
Byrne CD., Atherosclerosis 145(1), 1999
PMID: 10428291

Adenovirus-mediated overexpression of c-Jun and c-Fos induces intercellular adhesion molecule-1 and monocyte chemoattractant protein-1 in human endothelial cells.
Wang N, Verna L, Hardy S, Forsayeth J, Zhu Y, Stemerman MB., Arterioscler Thromb Vasc Biol 19(9), 1999
PMID: 10479648

Dietary lipid lowering reduces tissue factor expression in rabbit atheroma.
Aikawa M, Voglic SJ, Sugiyama S, Rabkin E, Taubman MB, Fallon JT, Libby P., Circulation 100(11), 1999
PMID: 10484543

Chlamydia pneumoniae infection of vascular smooth muscle and endothelial cells activates NF-kappaB and induces tissue factor and PAI-1 expression: a potential link to accelerated arteriosclerosis.
Dechend R, Maass M, Gieffers J, Dietz R, Scheidereit C, Leutz A, Gulba DC., Circulation 100(13), 1999
PMID: 10500035

Supplementation of N-acetylcysteine inhibits NFkappaB activation and protects against alloxan-induced diabetes in CD-1 mice.
Ho E, Chen G, Bray TM., FASEB J 13(13), 1999
PMID: 10506589

Oxidative stress as a regulator of gene expression in the vasculature.
Kunsch C, Medford RM., Circ Res 85(8), 1999
PMID: 10521248

Intimal deposition of functional von Willebrand factor in atherogenesis.
De Meyer GR, Hoylaerts MF, Kockx MM, Yamamoto H, Herman AG, Bult H., Arterioscler Thromb Vasc Biol 19(10), 1999
PMID: 10521383

Nuclear factor kappaB activity is essential for matrix metalloproteinase-1 and -3 upregulation in rabbit dermal fibroblasts.
Bond M, Baker AH, Newby AC., Biochem Biophys Res Commun 264(2), 1999
PMID: 10529402

Complement activation by oxidatively modified low-density lipoproteins.
Demacker PN., Eur J Clin Invest 29(10), 1999
PMID: 10583420

Ginkgo biloba inhibits hydrogen peroxide-induced activation of nuclear factor kappa B in vascular endothelial cells.
Wei Z, Peng Q, Lau BH, Shah V., Gen Pharmacol 33(5), 1999
PMID: 10553877

Possible role of proinflammatory cytokines in heart allograft coronary artery disease.
Gullestad L, Simonsen S, Ueland T, Holm T, Aass H, Andreassen AK, Madsen S, Geiran O, Frøland SS, Aukrust P., Am J Cardiol 84(9), 1999
PMID: 10569653

Prolonged activation of NF-kappaB following traumatic brain injury in rats.
Nonaka M, Chen XH, Pierce JE, Leoni MJ, McIntosh TK, Wolf JA, Smith DH., J Neurotrauma 16(11), 1999
PMID: 10595819

Management of oxidative stress in the CNS: the many roles of glutathione.
Juurlink BH., Neurotox Res 1(2), 1999
PMID: 12835108

Elevated circulating levels of C-C chemokines in patients with congestive heart failure.
Aukrust P, Ueland T, Müller F, Andreassen AK, Nordøy I, Aas H, Kjekshus J, Simonsen S, Frøland SS, Gullestad L., Circulation 97(12), 1998
PMID: 9537339

Biphasic regulation of transcription factor nuclear factor-kappaB activity in human endothelial cells by lysophosphatidylcholine through protein kinase C-mediated pathway.
Sugiyama S, Kugiyama K, Ogata N, Doi H, Ota Y, Ohgushi M, Matsumura T, Oka H, Yasue H., Arterioscler Thromb Vasc Biol 18(4), 1998
PMID: 9555862

Effect of linoleic acid on endothelial cell inflammatory mediators.
Young VM, Toborek M, Yang F, McClain CJ, Hennig B., Metabolism 47(5), 1998
PMID: 9591748

NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival.
Scatena M, Almeida M, Chaisson ML, Fausto N, Nicosia RF, Giachelli CM., J Cell Biol 141(4), 1998
PMID: 9585425

Application of transcription factor "decoy" strategy as means of gene therapy and study of gene expression in cardiovascular disease.
Morishita R, Higaki J, Tomita N, Ogihara T., Circ Res 82(10), 1998
PMID: 9622154

Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators.
Staels B, Koenig W, Habib A, Merval R, Lebret M, Torra IP, Delerive P, Fadel A, Chinetti G, Fruchart JC, Najib J, Maclouf J, Tedgui A., Nature 393(6687), 1998
PMID: 9655393

Redox signals and NF-kappaB activation in T cells.
Ginn-Pease ME, Whisler RL., Free Radic Biol Med 25(3), 1998
PMID: 9680181

Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa.
Rogler G, Brand K, Vogl D, Page S, Hofmeister R, Andus T, Knuechel R, Baeuerle PA, Schölmerich J, Gross V., Gastroenterology 115(2), 1998
PMID: 9679041

More cellular signals for atherogenesis?
Edgington T., Circulation 98(12), 1998
PMID: 9743503

Activated platelets induce monocyte chemotactic protein-1 secretion and surface expression of intercellular adhesion molecule-1 on endothelial cells.
Gawaz M, Neumann FJ, Dickfeld T, Koch W, Laugwitz KL, Adelsberger H, Langenbrink K, Page S, Neumeier D, Schömig A, Brand K., Circulation 98(12), 1998
PMID: 9743506

Nuclear factor-kappaB is selectively and markedly activated in humans with unstable angina pectoris.
Ritchie ME., Circulation 98(17), 1998
PMID: 9788823

The nuclear factor-kappa B/inhibitor of kappa B autoregulatory system and atherosclerosis.
Thurberg BL, Collins T., Curr Opin Lipidol 9(5), 1998
PMID: 9812192

Role of oxygen derived radicals for vascular dysfunction in the diabetic heart: prevention by alpha-tocopherol?
Rösen P, Du X, Tschöpe D., Mol Cell Biochem 188(1-2), 1998
PMID: 9823016

Nuclear factor kappa B: important transcription factor and therapeutic target.
Lee JI, Burckart GJ., J Clin Pharmacol 38(11), 1998
PMID: 9824778

alpha-Tocopherol enrichment of monocytes decreases agonist-induced adhesion to human endothelial cells.
Islam KN, Devaraj S, Jialal I., Circulation 98(21), 1998
PMID: 9826311

ACE inhibitor quinapril reduces the arterial expression of NF-kappaB-dependent proinflammatory factors but not of collagen I in a rabbit model of atherosclerosis.
Hernández-Presa MA, Bustos C, Ortego M, Tuñón J, Ortega L, Egido J., Am J Pathol 153(6), 1998
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Gene therapy for cerebral vascular disease.
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