Weird fingers: Functional analysis of WIP domain proteins

Appelhagen I, Huep G, Lu G-H, Strompen G, Weisshaar B, Sagasser M (2010)
FEBS Letters 584(14): 3116-3122.

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Abstract / Bemerkung
WIP proteins form a plant specific subfamily of C2H2 zinc finger (ZF) proteins. In this study, we functionally characterized the WIP domain, which consists of four ZF motifs, and discuss molecular functions for WIP proteins. Mutations in each of the ZFs lead to loss of function of the TT1/WIP1 protein in Arabiopsis thaliana. SV40 type nuclear localisation signals were detected in two of the ZFs and functionally characterized using GFP fusions as well as new mutant alleles identified by TILLING. Promoter swap experiments showed that selected WIP proteins are partially able to take over TT1 function. Activity of the AtBAN promoter, a potential TT1 target, could be increased by the addition of TT1 to the TT2-TT8-TTG1 regulatory complex. (C) 2010 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
Stichworte
Arabidopsis thaliana; Zinc finger; Nuclear localisation signal; Proanthocyanidins; Transcription factor; Transparent testa
Erscheinungsjahr
2010
Zeitschriftentitel
FEBS Letters
Band
584
Ausgabe
14
Seite(n)
3116-3122
ISSN
0014-5793
Page URI
https://pub.uni-bielefeld.de/record/1795171

Zitieren

Appelhagen I, Huep G, Lu G-H, Strompen G, Weisshaar B, Sagasser M. Weird fingers: Functional analysis of WIP domain proteins. FEBS Letters. 2010;584(14):3116-3122.
Appelhagen, I., Huep, G., Lu, G. - H., Strompen, G., Weisshaar, B., & Sagasser, M. (2010). Weird fingers: Functional analysis of WIP domain proteins. FEBS Letters, 584(14), 3116-3122. https://doi.org/10.1016/j.febslet.2010.06.007
Appelhagen, Ingo, Huep, Gunnar, Lu, Gui-Hua, Strompen, Georg, Weisshaar, Bernd, and Sagasser, Martin. 2010. “Weird fingers: Functional analysis of WIP domain proteins”. FEBS Letters 584 (14): 3116-3122.
Appelhagen, I., Huep, G., Lu, G. - H., Strompen, G., Weisshaar, B., and Sagasser, M. (2010). Weird fingers: Functional analysis of WIP domain proteins. FEBS Letters 584, 3116-3122.
Appelhagen, I., et al., 2010. Weird fingers: Functional analysis of WIP domain proteins. FEBS Letters, 584(14), p 3116-3122.
I. Appelhagen, et al., “Weird fingers: Functional analysis of WIP domain proteins”, FEBS Letters, vol. 584, 2010, pp. 3116-3122.
Appelhagen, I., Huep, G., Lu, G.-H., Strompen, G., Weisshaar, B., Sagasser, M.: Weird fingers: Functional analysis of WIP domain proteins. FEBS Letters. 584, 3116-3122 (2010).
Appelhagen, Ingo, Huep, Gunnar, Lu, Gui-Hua, Strompen, Georg, Weisshaar, Bernd, and Sagasser, Martin. “Weird fingers: Functional analysis of WIP domain proteins”. FEBS Letters 584.14 (2010): 3116-3122.

10 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

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