A simian virus 40-encoded protein of M r 74,000 daltons is structurally related to the capsid proteins of the virus

Krippl B, Dreiseikelmann B, Werchau H (1983)
Journal of Cellular Biochemistry 22(4): 197-207.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Abstract / Bemerkung
We have demonstrated the synthesis of a 74,000-dalton protein (74K protein) in African green monkey kidney cells infected with simian virus (SV)40. The 74K protein was detected late during the lytic cycle. Its synthesis was inhibited by arabinosyl cytosine as was the synthesis of the capsid proteins. Monospecific antibodies raised against VP1 and VP3 precipitated the structural proteins and the 74K protein. The 74K protein was not found in purified virions. Tryptic peptide analysis demonstrated that the 74K protein shares methionine- and serine-containing peptides with VP1 and VP3 and thus is structurally related to the capsid proteins.
Stichworte
structural proteins; tryptic peptide analysis; immunoprecipitation; SV40
Erscheinungsjahr
1983
Zeitschriftentitel
Journal of Cellular Biochemistry
Band
22
Ausgabe
4
Seite(n)
197-207
ISSN
0730-2312
eISSN
1097-4644
Page URI
https://pub.uni-bielefeld.de/record/1778569

Zitieren

Krippl B, Dreiseikelmann B, Werchau H. A simian virus 40-encoded protein of M r 74,000 daltons is structurally related to the capsid proteins of the virus. Journal of Cellular Biochemistry. 1983;22(4):197-207.
Krippl, B., Dreiseikelmann, B., & Werchau, H. (1983). A simian virus 40-encoded protein of M r 74,000 daltons is structurally related to the capsid proteins of the virus. Journal of Cellular Biochemistry, 22(4), 197-207. doi:10.1002/jcb.240220402
Krippl, B., Dreiseikelmann, B., and Werchau, H. (1983). A simian virus 40-encoded protein of M r 74,000 daltons is structurally related to the capsid proteins of the virus. Journal of Cellular Biochemistry 22, 197-207.
Krippl, B., Dreiseikelmann, B., & Werchau, H., 1983. A simian virus 40-encoded protein of M r 74,000 daltons is structurally related to the capsid proteins of the virus. Journal of Cellular Biochemistry, 22(4), p 197-207.
B. Krippl, B. Dreiseikelmann, and H. Werchau, “A simian virus 40-encoded protein of M r 74,000 daltons is structurally related to the capsid proteins of the virus”, Journal of Cellular Biochemistry, vol. 22, 1983, pp. 197-207.
Krippl, B., Dreiseikelmann, B., Werchau, H.: A simian virus 40-encoded protein of M r 74,000 daltons is structurally related to the capsid proteins of the virus. Journal of Cellular Biochemistry. 22, 197-207 (1983).
Krippl, Bernd, Dreiseikelmann, Brigitte, and Werchau, Hermann. “A simian virus 40-encoded protein of M r 74,000 daltons is structurally related to the capsid proteins of the virus”. Journal of Cellular Biochemistry 22.4 (1983): 197-207.
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