Variability of postsynaptic responses depends non-linearly on the number of synaptic inputs
Kretzberg J, Sejnowski T, Warzecha A-K, Egelhaaf M (2003)
Neurocomputing 52-54: 313-320.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
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Abstract / Bemerkung
A conductance-based model for synaptic transmission and postsynaptic integration reveals how postsynaptic responses and their variability depend on the number of synaptic inputs. With increasing number of balanced stochastic excitatory and inhibitory inputs, the postsynaptic responses and their variance first increase and then decrease again. This non-linearity can be attributed to an anti-correlation between the total excitatory and inhibitory currents. The anti-correlation, which occurs even though the conductances of the individual synapses vary independently of each other, is determined by the total synaptic conductance and grows with the number of inputs. As the number of inputs increases, the membrane potential comes increasingly closer to the resting level.
Stichworte
Correlated synaptic currents;
Number of inputs;
Model;
Graded synaptic transmission;
Synaptic conductances
Erscheinungsjahr
2003
Zeitschriftentitel
Neurocomputing
Band
52-54
Seite(n)
313-320
ISSN
0925-2312
Page URI
https://pub.uni-bielefeld.de/record/1773449
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Kretzberg J, Sejnowski T, Warzecha A-K, Egelhaaf M. Variability of postsynaptic responses depends non-linearly on the number of synaptic inputs. Neurocomputing. 2003;52-54:313-320.
Kretzberg, J., Sejnowski, T., Warzecha, A. - K., & Egelhaaf, M. (2003). Variability of postsynaptic responses depends non-linearly on the number of synaptic inputs. Neurocomputing, 52-54, 313-320. https://doi.org/10.1016/S0925-2312(02)00797-X
Kretzberg, Jutta, Sejnowski, Terrence, Warzecha, Anne-Kathrin, and Egelhaaf, Martin. 2003. “Variability of postsynaptic responses depends non-linearly on the number of synaptic inputs”. Neurocomputing 52-54: 313-320.
Kretzberg, J., Sejnowski, T., Warzecha, A. - K., and Egelhaaf, M. (2003). Variability of postsynaptic responses depends non-linearly on the number of synaptic inputs. Neurocomputing 52-54, 313-320.
Kretzberg, J., et al., 2003. Variability of postsynaptic responses depends non-linearly on the number of synaptic inputs. Neurocomputing, 52-54, p 313-320.
J. Kretzberg, et al., “Variability of postsynaptic responses depends non-linearly on the number of synaptic inputs”, Neurocomputing, vol. 52-54, 2003, pp. 313-320.
Kretzberg, J., Sejnowski, T., Warzecha, A.-K., Egelhaaf, M.: Variability of postsynaptic responses depends non-linearly on the number of synaptic inputs. Neurocomputing. 52-54, 313-320 (2003).
Kretzberg, Jutta, Sejnowski, Terrence, Warzecha, Anne-Kathrin, and Egelhaaf, Martin. “Variability of postsynaptic responses depends non-linearly on the number of synaptic inputs”. Neurocomputing 52-54 (2003): 313-320.
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Daten bereitgestellt von European Bioinformatics Institute (EBI)
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Daten bereitgestellt von Europe PubMed Central.
5 References
Daten bereitgestellt von Europe PubMed Central.
The intrinsic electrophysiological characteristics of fly lobula plate tangential cells: I. Passive membrane properties.
Borst A, Haag J., J Comput Neurosci 3(4), 1996
PMID: 9001975
Borst A, Haag J., J Comput Neurosci 3(4), 1996
PMID: 9001975
Gain modulation from background synaptic input.
Chance FS, Abbott LF, Reyes AD., Neuron 35(4), 2002
PMID: 12194875
Chance FS, Abbott LF, Reyes AD., Neuron 35(4), 2002
PMID: 12194875
Membrane potential fluctuations determine the precision of spike timing and synchronous activity: a model study.
Kretzberg J, Egelhaaf M, Warzecha AK., J Comput Neurosci 10(1), 2001
PMID: 11316342
Kretzberg J, Egelhaaf M, Warzecha AK., J Comput Neurosci 10(1), 2001
PMID: 11316342
Roberts, 1981
Reliability of a fly motion-sensitive neuron depends on stimulus parameters.
Warzecha AK, Kretzberg J, Egelhaaf M., J. Neurosci. 20(23), 2000
PMID: 11102498
Warzecha AK, Kretzberg J, Egelhaaf M., J. Neurosci. 20(23), 2000
PMID: 11102498
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