The maturation of the acetylcholine system in the dentate gyrus of gerbils (Meriones unguiculatus) is affected by epigenetic factors.

Busche A, Bagorda A, Lehmann K, Neddens J, Teuchert-Noodt G (2006)
J Neural Transm 113(2): 113-124.

Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Autor
; ; ; ;
Abstract / Bemerkung
The current study investigated the influence of impoverished rearing (IR) conditions and a single early methamphetamine challenge (MA; 50 mg/kg i.p.) on day 14 on the postnatal maturation of acetylcholinesterase-positive (AChE+) fibres in the hippocampal dentate gyrus (DG) of gerbils (Meriones unguiculatus). The layer-specific densities of histochemically stained AChE+ fibres were quantified in two planes of the left and right DG in young adults (day 90). Compared to enriched reared (ER) animals, the AChE+ fibre densities turned out to be higher in both the septal and the temporal plane of both hemispheres in saline treated IR and MA treated ER gerbils. The temporal plane was slightly more affected than the septal plane. In IR animals, MA treatment selectively diminished the AChE+ fibre densities in the subgranular layer of both left and right temporal DG. In conclusion, the maturation of AChE+ fibres is vulnerable to both rearing conditions and early MA challenge. The results correlate with our previous studies on the dentate cell proliferation rates and the serotonergic innervation, two parameters which are similarly affected by the experimental design. Thus, disturbances of the ACh system may impair the hippocampal plasticity and hippocampus-related cognitive and emotional function.
Erscheinungsjahr
Zeitschriftentitel
J Neural Transm
Band
113
Zeitschriftennummer
2
Seite
113-124
ISSN
eISSN
PUB-ID

Zitieren

Busche A, Bagorda A, Lehmann K, Neddens J, Teuchert-Noodt G. The maturation of the acetylcholine system in the dentate gyrus of gerbils (Meriones unguiculatus) is affected by epigenetic factors. J Neural Transm. 2006;113(2):113-124.
Busche, A., Bagorda, A., Lehmann, K., Neddens, J., & Teuchert-Noodt, G. (2006). The maturation of the acetylcholine system in the dentate gyrus of gerbils (Meriones unguiculatus) is affected by epigenetic factors. J Neural Transm, 113(2), 113-124. doi:10.1007/s00702-005-0317-1
Busche, A., Bagorda, A., Lehmann, K., Neddens, J., and Teuchert-Noodt, G. (2006). The maturation of the acetylcholine system in the dentate gyrus of gerbils (Meriones unguiculatus) is affected by epigenetic factors. J Neural Transm 113, 113-124.
Busche, A., et al., 2006. The maturation of the acetylcholine system in the dentate gyrus of gerbils (Meriones unguiculatus) is affected by epigenetic factors. J Neural Transm, 113(2), p 113-124.
A. Busche, et al., “The maturation of the acetylcholine system in the dentate gyrus of gerbils (Meriones unguiculatus) is affected by epigenetic factors.”, J Neural Transm, vol. 113, 2006, pp. 113-124.
Busche, A., Bagorda, A., Lehmann, K., Neddens, J., Teuchert-Noodt, G.: The maturation of the acetylcholine system in the dentate gyrus of gerbils (Meriones unguiculatus) is affected by epigenetic factors. J Neural Transm. 113, 113-124 (2006).
Busche, A, Bagorda, A, Lehmann, K, Neddens, J, and Teuchert-Noodt, Gertraud. “The maturation of the acetylcholine system in the dentate gyrus of gerbils (Meriones unguiculatus) is affected by epigenetic factors.”. J Neural Transm 113.2 (2006): 113-124.

7 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Developmental neuroplasticity and the origin of neurodegenerative diseases.
Schaefers AT, Teuchert-Noodt G., World J Biol Psychiatry 17(8), 2016
PMID: 23705632
Choline status and neurodevelopmental outcomes at 5 years of age in the Seychelles Child Development Nutrition Study.
Strain JJ, McSorley EM, van Wijngaarden E, Kobrosly RW, Bonham MP, Mulhern MS, McAfee AJ, Davidson PW, Shamlaye CF, Henderson J, Watson GE, Thurston SW, Wallace JM, Ueland PM, Myers GJ., Br J Nutr 110(2), 2013
PMID: 23298754
Activity-dependent structural plasticity.
Butz M, Wörgötter F, van Ooyen A., Brain Res Rev 60(2), 2009
PMID: 19162072

83 References

Daten bereitgestellt von Europe PubMed Central.

The effects of physostigmine and scopolamine on recognition memory in monkeys.
Aigner TG, Mishkin M., Behav. Neural Biol. 45(1), 1986
PMID: 3954717

AUTHOR UNKNOWN, 0
Effects of early isolation on layer II neurons in the entorhinal cortex of the guinea pig.
Bartesaghi R, Raffi M, Severi S., Neuroscience 120(3), 2003
PMID: 12895512
Effects of early environment on pyramidal neuron morphology in field CA1 of the guinea-pig.
Bartesaghi R, Severi S, Guidi S., Neuroscience 116(3), 2003
PMID: 12573714
Immunolesion of the cholinergic basal forebrain: effects on functional properties of hippocampal and septal neurons.
Bassant MH, Jouvenceau A, Apartis E, Poindessous-Jazat F, Dutar P, Billard JM., Int. J. Dev. Neurosci. 16(7-8), 1998
PMID: 10198811

L, Proc Natl Acad Sci USA 100(), 2003
Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus.
Cameron HA, Gould E., Neuroscience 61(2), 1994
PMID: 7969902
Decreased neurogenesis after cholinergic forebrain lesion in the adult rat.
Cooper-Kuhn CM, Winkler J, Kuhn HG., J. Neurosci. Res. 77(2), 2004
PMID: 15211583

RR, J Neural Transm 105(), 1998

RR, J Neural Transm 107(), 2000
Perforant path lesioning induces sprouting of CA3-associated fibre systems in mouse hippocampal formation.
Drojdahl N, Hegelund IV, Poulsen FR, Wree A, Finsen B., Exp Brain Res 144(1), 2002
PMID: 11976761
Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment.
Falkenberg T, Mohammed AK, Henriksson B, Persson H, Winblad B, Lindefors N., Neurosci. Lett. 138(1), 1992
PMID: 1407655
Cholinergic sprouting in the rat fascia dentata after entorhinal lesion is not linked to early changes in neurotrophin messenger RNA expression.
Forster E, Naumann T, Deller T, Straube A, Nitsch R, Frotscher M., Neuroscience 80(3), 1997
PMID: 9276489
Effects of 192 IgG-saporin on acetylcholinesterase histochemistry in male and female rats.
Galani R, Jeltsch H, Lehmann O, Bertrand F, Cassel JC., Brain Res. Bull. 58(2), 2002
PMID: 12127015

E, Dev Brain Res 103(), 1997
Endogenous glutamate levels regulate nerve growth factor mRNA expression in the rat dentate gyrus.
Gwag BJ, Sessler FM, Robine V, Springer JE., Mol. Cells 7(3), 1997
PMID: 9264033

AUTHOR UNKNOWN, 0

K, J Neural Transm 106(), 1999
Structure and function of the brain serotonin system.
Jacobs BL, Azmitia EC., Physiol. Rev. 72(1), 1992
PMID: 1731370
Mitotic neuroblasts in the 9-day-old and 11-month-old rodent hippocampus.
Kaplan MS, Bell DH., J. Neurosci. 4(6), 1984
PMID: 6726341
The cholinergic systems in brain and spinal cord.
Kasa P., Prog. Neurobiol. 26(3), 1986
PMID: 3523620

A, Neurol Psychiat Brain Res 8(), 2000
More hippocampal neurons in adult mice living in an enriched environment.
Kempermann G, Kuhn HG, Gage FH., Nature 386(6624), 1997
PMID: 9087407
Experience-induced neurogenesis in the senescent dentate gyrus.
Kempermann G, Kuhn HG, Gage FH., J. Neurosci. 18(9), 1998
PMID: 9547229
Cellular localization of NGF and NT-3 mRNAs in postnatal rat forebrain.
Lauterborn JC, Isackson PJ, Gall CM., Mol. Cell. Neurosci. 5(1), 1994
PMID: 8087414
Acetylcholine stimulates cortical precursor cell proliferation in vitro via muscarinic receptor activation and MAP kinase phosphorylation.
Ma W, Maric D, Li BS, Hu Q, Andreadis JD, Grant GM, Liu QY, Shaffer KM, Chang YH, Zhang L, Pancrazio JJ, Pant HC, Stenger DA, Barker JL., Eur. J. Neurosci. 12(4), 2000
PMID: 10762352
NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression.
Maisonpierre PC, Belluscio L, Friedman B, Alderson RF, Wiegand SJ, Furth ME, Lindsay RM, Yancopoulos GD., Neuron 5(4), 1990
PMID: 1688327
Arrival of afferents and the differentiation of target neurons: studies of developing cholinergic projections to the dentate gyrus.
Makuch R, Baratta J, Karaelias LD, Lauterborn JC, Gall CM, Yu J, Robertson RT., Neuroscience 104(1), 2001
PMID: 11311533
Activation of nicotinic acetylcholine receptors induces long-term potentiation in vivo in the intact mouse dentate gyrus.
Matsuyama S, Matsumoto A, Enomoto T, Nishizaki T., Eur. J. Neurosci. 12(10), 2000
PMID: 11029644
Environmental influences on the central nervous system and their implications for the aging rat.
Mohammed AH, Henriksson BG, Soderstrom S, Ebendal T, Olsson T, Seckl JR., Behav. Brain Res. 57(2), 1993
PMID: 8117423

AUTHOR UNKNOWN, 0

J, J Neural Transm 109(), 2002

J, Dev Brain Res 146(), 2003
Postnatal maturation of cortical serotonin lateral asymmetry in gerbils is vulnerable to both environmental and pharmacological epigenetic challenges.
Neddens J, Dawirs RR, Bagorda F, Busche A, Horstmann S, Teuchert-Noodt G., Brain Res. 1021(2), 2004
PMID: 15342268
A single dose of methamphetamine in neonatal gerbils affects adult prefrontal gamma-aminobutyric acid innervation.
Nossoll M, Teuchert-Noodt G, Dawirs RR., Eur. J. Pharmacol. 340(2-3), 1997
PMID: 9537803

T, Mol Brain Res 23(), 1994
Effects of environmental enrichment on cognitive function and hippocampal NGF in the non-handled rats.
Pham TM, Soderstrom S, Winblad B, Mohammed AH., Behav. Brain Res. 103(1), 1999
PMID: 10475165
Environmental influences on brain neurotrophins in rats.
Pham TM, Winblad B, Granholm AC, Mohammed AH., Pharmacol. Biochem. Behav. 73(1), 2002
PMID: 12076736
Cerebral changes in rats exposed individually to an enriched environment.
Rosenzweig MR, Bennett EL., J Comp Physiol Psychol 80(2), 1972
PMID: 5047833
Social grouping cannot account for cerebral effects of enriched environments.
Rosenzweig MR, Bennett EL, Hebert M, Morimoto H., Brain Res. 153(3), 1978
PMID: 698794

JE, Mol Brain Res 23(), 1994

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

G, J Neural Transm 107(), 2000
Development of the basal forebrain cholinergic system: phenotype expression prior to target innervation.
Thal LJ, Gilbertson E, Armstrong DM, Gage FH., Neurobiol. Aging 13(1), 1992
PMID: 1542384

H, Nature Rev 1(), 2000
Expression of neurotrophin-3 in the mouse forebrain: insights from a targeted LacZ reporter.
Vigers AJ, Baquet ZC, Jones KR., J. Comp. Neurol. 416(3), 2000
PMID: 10602097
Effects of social isolation rearing on learning in the Morris water maze.
Wongwitdecha N, Marsden CA., Brain Res. 715(1-2), 1996
PMID: 8739630
Effect of isolation rearing on 5-HT agonist-induced responses in the rat.
Wright IK, Ismail H, Upton N, Marsden CA., Psychopharmacology (Berl.) 105(2), 1991
PMID: 1839066

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 15959847
PubMed | Europe PMC

Suchen in

Google Scholar