How old is the genetic code? Statistical geometry of tRNA provides an answer

Eigen M, Lindemann BF, Tietze M, Winkler-Oswatitsch R, Dress A, von Haeseler A (1989)
Science 244(4905): 673-679.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Eigen, Manfred; Lindemann, Bjorn F. ; Tietze, Manfred ; Winkler-Oswatitsch, Ruthild ; Dress, AndreasUniBi; von Haeseler , Arndt
Abstract / Bemerkung
The age of the molecular organization of life as expressed in the genetic code can be estimated from experimental data. Comparative sequence analysis of transfer RNA by the method of statistical geometry in sequence space suggests that about one-third of the present transfer RNA sequence divergence was present at the urkingdom level about the time when archaebacteria separated from eubacteria. It is concluded that the genetic code is not older than, but almost as old as our planet. While this result may not be unexpected, it was not clear until now that interpretable data exist that permit inferences about such early stages of life as the establishment of the genetic code.
Erscheinungsjahr
1989
Zeitschriftentitel
Science
Band
244
Ausgabe
4905
Seite(n)
673-679
ISSN
0036-8075
eISSN
1095-9203
Page URI
https://pub.uni-bielefeld.de/record/1653048

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Eigen M, Lindemann BF, Tietze M, Winkler-Oswatitsch R, Dress A, von Haeseler A. How old is the genetic code? Statistical geometry of tRNA provides an answer. Science. 1989;244(4905):673-679.
Eigen, M., Lindemann, B. F., Tietze, M., Winkler-Oswatitsch, R., Dress, A., & von Haeseler , A. (1989). How old is the genetic code? Statistical geometry of tRNA provides an answer. Science, 244(4905), 673-679. https://doi.org/10.1126/science.2497522
Eigen, M., Lindemann, B. F., Tietze, M., Winkler-Oswatitsch, R., Dress, A., and von Haeseler , A. (1989). How old is the genetic code? Statistical geometry of tRNA provides an answer. Science 244, 673-679.
Eigen, M., et al., 1989. How old is the genetic code? Statistical geometry of tRNA provides an answer. Science, 244(4905), p 673-679.
M. Eigen, et al., “How old is the genetic code? Statistical geometry of tRNA provides an answer”, Science, vol. 244, 1989, pp. 673-679.
Eigen, M., Lindemann, B.F., Tietze, M., Winkler-Oswatitsch, R., Dress, A., von Haeseler , A.: How old is the genetic code? Statistical geometry of tRNA provides an answer. Science. 244, 673-679 (1989).
Eigen, Manfred, Lindemann, Bjorn F., Tietze, Manfred, Winkler-Oswatitsch, Ruthild, Dress, Andreas, and von Haeseler , Arndt. “How old is the genetic code? Statistical geometry of tRNA provides an answer”. Science 244.4905 (1989): 673-679.

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