The serotonin transporter gene and peer-rated neuroticism

Ball D, Hill L, Freeman B, Eley TC, Strelau J, Riemann R, Spinath FM, Angleitner A, Plomin R (1997)
NEUROREPORT 8(5): 1301-1304.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor/in
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Abstract / Bemerkung
POLYMORPHISMS in the serotonin transporter gene (5HTT) have been reported to be associated with neuroticism (emotionality) and with depression. A recent report of an association between 5HTT and neuroticism involved unselected samples and self-report questionnaires.(1) We attempted to extend these findings using a selected extremes design and peer ratings. From a sample of 2085 individuals, each assessed on neuroticism by two independent peers, we selected 52 individuals from the top 5% and 54 individuals from the bottom 5%. No association was found for either a functional 44 bp insertion/deletion polymorphism in 5HTT regulatory sequence (5HTTLPR) or for a non-functional variable number tandem repeat 5HTT polymorphism.
Stichworte
transporter; risk factors; polymorphism; depression; neuroticism; serotonin
Erscheinungsjahr
1997
Zeitschriftentitel
NEUROREPORT
Band
8
Ausgabe
5
Seite(n)
1301-1304
ISSN
0959-4965
Page URI
https://pub.uni-bielefeld.de/record/1637195

Zitieren

Ball D, Hill L, Freeman B, et al. The serotonin transporter gene and peer-rated neuroticism. NEUROREPORT. 1997;8(5):1301-1304.
Ball, D., Hill, L., Freeman, B., Eley, T. C., Strelau, J., Riemann, R., Spinath, F. M., et al. (1997). The serotonin transporter gene and peer-rated neuroticism. NEUROREPORT, 8(5), 1301-1304. doi:10.1097/00001756-199703240-00048
Ball, D., Hill, L., Freeman, B., Eley, T. C., Strelau, J., Riemann, R., Spinath, F. M., Angleitner, A., and Plomin, R. (1997). The serotonin transporter gene and peer-rated neuroticism. NEUROREPORT 8, 1301-1304.
Ball, D., et al., 1997. The serotonin transporter gene and peer-rated neuroticism. NEUROREPORT, 8(5), p 1301-1304.
D. Ball, et al., “The serotonin transporter gene and peer-rated neuroticism”, NEUROREPORT, vol. 8, 1997, pp. 1301-1304.
Ball, D., Hill, L., Freeman, B., Eley, T.C., Strelau, J., Riemann, R., Spinath, F.M., Angleitner, A., Plomin, R.: The serotonin transporter gene and peer-rated neuroticism. NEUROREPORT. 8, 1301-1304 (1997).
Ball, D, Hill, L, Freeman, B, Eley, TC, Strelau, J, Riemann, Rainer, Spinath, FM, Angleitner, Alois, and Plomin, R. “The serotonin transporter gene and peer-rated neuroticism”. NEUROREPORT 8.5 (1997): 1301-1304.

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PMID: 9175133
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