Oxidative Burst Inhibitory and Cytotoxic Indoloquinazoline and Furoquinoline Alkaloids from Oricia suaveolens

Wansi J, Mesaik MA, Chiozem DD, Devkota KP, Gaboriaud-Kolar N, Lallemand M-C, Wandji J, Choudhary MI, Sewald N (2008)
Journal of Natural Products 71(11): 1942-1945.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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DOI
Autor*in
Wansi, JeanUniBi; Mesaik, M. Ahmed; Chiozem, David Dako; Devkota, Krishna Prasad; Gaboriaud-Kolar, Nicolas; Lallemand, Marie-Christine; Wandji, Jean; Choudhary, M. Iqbal; Sewald, NorbertUniBi
Einrichtung
Fakultät für Chemie > Organische Chemie III
Centrum für Biotechnologie > Arbeitsgruppe N. Sewald
Centrum für Biotechnologie > Institut für Biochemie und Biotechnik
Abstract / Bemerkung
Two new beta-indoloquinazoline alkaloids, orisuaveoline A (1) and orisuaveoline B (2), two new furoquinoline alkaloids, quinosuaveoline A (5) and quinosuaveoline B (6), and 12 known compounds were isolated from Oricia suaveolens. The structures of the new compounds were deduced by spectroscopic studies. The absolute configuration of nkolbisine (4) was also determined. Compounds 2, 3, 6-8, 10, and 14 were evaluated for oxidative burst inhibitory activity in a chemoluminescence assay and for cytotoxicity against A549 lung carcinoma cells.
Erscheinungsjahr
2008
Zeitschriftentitel
Journal of Natural Products
Band
71
Ausgabe
11
Seite(n)
1942-1945
ISSN
0163-3864
eISSN
1520-6025
Page URI
https://pub.uni-bielefeld.de/record/1636658

Zitieren

Wansi J, Mesaik MA, Chiozem DD, et al. Oxidative Burst Inhibitory and Cytotoxic Indoloquinazoline and Furoquinoline Alkaloids from Oricia suaveolens. Journal of Natural Products. 2008;71(11):1942-1945.
Wansi, J., Mesaik, M. A., Chiozem, D. D., Devkota, K. P., Gaboriaud-Kolar, N., Lallemand, M. - C., Wandji, J., et al. (2008). Oxidative Burst Inhibitory and Cytotoxic Indoloquinazoline and Furoquinoline Alkaloids from Oricia suaveolens. Journal of Natural Products, 71(11), 1942-1945. https://doi.org/10.1021/np800276f
Wansi, Jean, Mesaik, M. Ahmed, Chiozem, David Dako, Devkota, Krishna Prasad, Gaboriaud-Kolar, Nicolas, Lallemand, Marie-Christine, Wandji, Jean, Choudhary, M. Iqbal, and Sewald, Norbert. 2008. “Oxidative Burst Inhibitory and Cytotoxic Indoloquinazoline and Furoquinoline Alkaloids from Oricia suaveolens”. Journal of Natural Products 71 (11): 1942-1945.
Wansi, J., Mesaik, M. A., Chiozem, D. D., Devkota, K. P., Gaboriaud-Kolar, N., Lallemand, M. - C., Wandji, J., Choudhary, M. I., and Sewald, N. (2008). Oxidative Burst Inhibitory and Cytotoxic Indoloquinazoline and Furoquinoline Alkaloids from Oricia suaveolens. Journal of Natural Products 71, 1942-1945.
Wansi, J., et al., 2008. Oxidative Burst Inhibitory and Cytotoxic Indoloquinazoline and Furoquinoline Alkaloids from Oricia suaveolens. Journal of Natural Products, 71(11), p 1942-1945.
J. Wansi, et al., “Oxidative Burst Inhibitory and Cytotoxic Indoloquinazoline and Furoquinoline Alkaloids from Oricia suaveolens”, Journal of Natural Products, vol. 71, 2008, pp. 1942-1945.
Wansi, J., Mesaik, M.A., Chiozem, D.D., Devkota, K.P., Gaboriaud-Kolar, N., Lallemand, M.-C., Wandji, J., Choudhary, M.I., Sewald, N.: Oxidative Burst Inhibitory and Cytotoxic Indoloquinazoline and Furoquinoline Alkaloids from Oricia suaveolens. Journal of Natural Products. 71, 1942-1945 (2008).
Wansi, Jean, Mesaik, M. Ahmed, Chiozem, David Dako, Devkota, Krishna Prasad, Gaboriaud-Kolar, Nicolas, Lallemand, Marie-Christine, Wandji, Jean, Choudhary, M. Iqbal, and Sewald, Norbert. “Oxidative Burst Inhibitory and Cytotoxic Indoloquinazoline and Furoquinoline Alkaloids from Oricia suaveolens”. Journal of Natural Products 71.11 (2008): 1942-1945.

7 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Antimicrobial Furoquinoline Alkaloids from Vepris lecomteana (Pierre) Cheek & T. Heller (Rutaceae).
Kouam ADK, Bissoue AN, Tcho AT, Happi EN, Waffo AFK, Sewald N, Wansi JD., Molecules 23(1), 2017
PMID: 29267257
New furoquinoline alkaloid and flavanone glycoside derivatives from the leaves of Oricia suaveolens and Oricia renieri (Rutaceae).
Nouga AB, Ndom JC, Mpondo EM, Nyobe JC, Njoya A, Meva'a LM, Cranwell PB, Howell JA, Harwood LM, Wansi JD., Nat Prod Res 30(3), 2016
PMID: 26222678
Antiviral Activity of a Novel Compound CW-33 against Japanese Encephalitis Virus through Inhibiting Intracellular Calcium Overload.
Huang SH, Lien JC, Chen CJ, Liu YC, Wang CY, Ping CF, Lin YF, Huang AC, Lin CW., Int J Mol Sci 17(9), 2016
PMID: 27563890
Hexafluoroisopropyl alcohol mediated synthesis of 2,3-dihydro-4H-pyrido[1,2-a]pyrimidin-4-ones.
Alam MA, Alsharif Z, Alkhattabi H, Jones D, Delancey E, Gottsponer A, Yang T., Sci Rep 6(), 2016
PMID: 27805054
Antiviral Potential of a Novel Compound CW-33 against Enterovirus A71 via Inhibition of Viral 2A Protease.
Wang CY, Huang AC, Hour MJ, Huang SH, Kung SH, Chen CH, Chen IC, Chang YS, Lien JC, Lin CW., Viruses 7(6), 2015
PMID: 26090728
Immunosuppressive activity of buxidin and E-buxenone from Buxus hyrcana.
Mesaik MA, Halim SA, Ul-Haq Z, Choudhary MI, Shahnaz S, Ayatollahi SA, Murad S, Ahmad A., Chem Biol Drug Des 75(3), 2010
PMID: 20659112
Simple indole alkaloids and those with a nonrearranged monoterpenoid unit.
Ishikura M, Yamada K, Abe T., Nat Prod Rep 27(11), 2010
PMID: 20838695
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