Amides from the Stem Bark of Fagara macrophylla
Wansi J, Nwozo SO, Mbaze LM'a, Devkota KP, Moladje SMD, Fornum ZT, Sewald N (2009)
Planta Medica 75(05): 517-521.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
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Autor*in
Wansi, JeanUniBi;
Nwozo, Sarah Onyenibe;
Mbaze, Luc Meva'a;
Devkota, Krishna Prasad;
Moladje, Suzye Mireille Donkwe;
Fornum, Zacharias Tanee;
Sewald, NorbertUniBi 
Einrichtung
Abstract / Bemerkung
Five new amide alkaloids, N-(4-hydroxyphenethyl)octacosanamide (1), N-(4-hydroxyphenethyl)hexacosanamide (2), N-(4-hydroxyphenethyl)decanamide (3), N-vanilloyltyramine (4), and N-[O-docosanoylvanilloyl]tyramine (5), were isolated from Fagara macrophylla, together with 15 known compounds. Their structures were established by using spectroscopic techniques, chemical reactions, and comparison with previously known analogues. A cytotoxicity assay was performed with the isolates, in which compounds 4, 8, and 9 were found to possess moderate to weak activity, with IC50 values of 30.5, 11.5, and 13.5 mu g/mL, respectively.
Stichworte
Fagara macrophylla;
amide alkaloids;
Rutaceae;
cytotoxicity
Erscheinungsjahr
2009
Zeitschriftentitel
Planta Medica
Band
75
Ausgabe
05
Seite(n)
517-521
ISSN
0032-0943
eISSN
1439-0221
Page URI
https://pub.uni-bielefeld.de/record/1634144
Zitieren
Wansi J, Nwozo SO, Mbaze LM'a, et al. Amides from the Stem Bark of Fagara macrophylla. Planta Medica. 2009;75(05):517-521.
Wansi, J., Nwozo, S. O., Mbaze, L. M. 'a, Devkota, K. P., Moladje, S. M. D., Fornum, Z. T., & Sewald, N. (2009). Amides from the Stem Bark of Fagara macrophylla. Planta Medica, 75(05), 517-521. https://doi.org/10.1055/s-0029-1185327
Wansi, Jean, Nwozo, Sarah Onyenibe, Mbaze, Luc Meva'a, Devkota, Krishna Prasad, Moladje, Suzye Mireille Donkwe, Fornum, Zacharias Tanee, and Sewald, Norbert. 2009. “Amides from the Stem Bark of Fagara macrophylla”. Planta Medica 75 (05): 517-521.
Wansi, J., Nwozo, S. O., Mbaze, L. M. 'a, Devkota, K. P., Moladje, S. M. D., Fornum, Z. T., and Sewald, N. (2009). Amides from the Stem Bark of Fagara macrophylla. Planta Medica 75, 517-521.
Wansi, J., et al., 2009. Amides from the Stem Bark of Fagara macrophylla. Planta Medica, 75(05), p 517-521.
J. Wansi, et al., “Amides from the Stem Bark of Fagara macrophylla”, Planta Medica, vol. 75, 2009, pp. 517-521.
Wansi, J., Nwozo, S.O., Mbaze, L.M.'a, Devkota, K.P., Moladje, S.M.D., Fornum, Z.T., Sewald, N.: Amides from the Stem Bark of Fagara macrophylla. Planta Medica. 75, 517-521 (2009).
Wansi, Jean, Nwozo, Sarah Onyenibe, Mbaze, Luc Meva'a, Devkota, Krishna Prasad, Moladje, Suzye Mireille Donkwe, Fornum, Zacharias Tanee, and Sewald, Norbert. “Amides from the Stem Bark of Fagara macrophylla”. Planta Medica 75.05 (2009): 517-521.
3 Zitationen in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
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