ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN

Tschesche, Harald; Groeger, C.; Wenzel, Herbert

ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN

Tschesche H, Groeger C, Wenzel H (1991)
In: Emerg Med J. BIOMEDICA BIOCHIMICA ACTA, 50(10-11). AKADEMIE VERLAG GMBH: S175-S180.

Konferenzbeitrag | Veröffentlicht | Englisch

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Autor*in

Tschesche, Harald^UniBi; Groeger, C.; Wenzel, Herbert^UniBi

Einrichtung

Fakultät für Chemie > Biochemie I

Abstract / Bemerkung

An easy and rapid enzymatic method is described which allows replacement of P'-residues in bovine pancreatic trypsin inhibitor. Insertion of Xaa-Arg or Xaa-Lys into a BPTI fragment lacking P1' = Ala16 and P2' = Arg17 was carried out in a "one pot" reaction catalysed by trypsin in the presence of 80% 1,4 butanediol.

Erscheinungsjahr

1991

Titel des Konferenzbandes

Emerg Med J

Serien- oder Zeitschriftentitel

BIOMEDICA BIOCHIMICA ACTA

Band

Ausgabe

10-11

Seite(n)

S175-S180

ISSN

0232-766X

Page URI

https://pub.uni-bielefeld.de/record/1629600

Zitieren

Tschesche H, Groeger C, Wenzel H. ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN. In: Emerg Med J. BIOMEDICA BIOCHIMICA ACTA. Vol 50. AKADEMIE VERLAG GMBH; 1991: S175-S180.

Tschesche, H., Groeger, C., & Wenzel, H. (1991). ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN. Emerg Med J, BIOMEDICA BIOCHIMICA ACTA, 50, S175-S180. AKADEMIE VERLAG GMBH.

Tschesche, Harald, Groeger, C., and Wenzel, Herbert. 1991. “ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN”. In Emerg Med J, 50:S175-S180. BIOMEDICA BIOCHIMICA ACTA. AKADEMIE VERLAG GMBH.

Tschesche, H., Groeger, C., and Wenzel, H. (1991). “ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN” in Emerg Med J BIOMEDICA BIOCHIMICA ACTA, vol. 50, (AKADEMIE VERLAG GMBH), S175-S180.

Tschesche, H., Groeger, C., & Wenzel, H., 1991. ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN. In Emerg Med J. BIOMEDICA BIOCHIMICA ACTA. no.50 AKADEMIE VERLAG GMBH, pp. S175-S180.

H. Tschesche, C. Groeger, and H. Wenzel, “ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN”, Emerg Med J, BIOMEDICA BIOCHIMICA ACTA, vol. 50, AKADEMIE VERLAG GMBH, 1991, pp.S175-S180.

Tschesche, H., Groeger, C., Wenzel, H.: ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN. Emerg Med J. BIOMEDICA BIOCHIMICA ACTA. 50, p. S175-S180. AKADEMIE VERLAG GMBH (1991).

Tschesche, Harald, Groeger, C., and Wenzel, Herbert. “ENZYMATIC FRAGMENT SUBSTITUTION AS A TOOL IN PROTEIN DESIGN”. Emerg Med J. AKADEMIE VERLAG GMBH, 1991.Vol. 50. BIOMEDICA BIOCHIMICA ACTA. S175-S180.