EXPRESSION OF A BIOLOGICALLY-ACTIVE MURINE TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) IN BACULOVIRUS-INFECTED INSECT CELLS - PURIFICATION AND TISSUE DISTRIBUTION IN THE RAT

KURSCHAT P, GRAEVE L, ERREN A, GATSIOS P, ROSEJOHN S, ROEB E, Tschesche H, KOJ A, HEINRICH PC (1995)
EUROPEAN JOURNAL OF BIOCHEMISTRY 234(2): 485-491.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
KURSCHAT, P; GRAEVE, L; ERREN, A; GATSIOS, P; ROSEJOHN, S; ROEB, E; Tschesche, HaraldUniBi; KOJ, A; HEINRICH, PC
Abstract / Bemerkung
Murine tissue inhibitor of metalloproteinases-1 (mTIMP-1) was expressed in baculovirus-infected insect cells (Sf9). The protein secreted into the culture medium was purified to homogeneity by means of heparin-Sepharose CL-6B and FPLC. The purified protein showed metalloproteinase-inhibitory activity in two independent assays: reverse zymography and inhibition of collagenase activity. Digestion of the recombinant TIMP-1 with peptide-N-glycanaseF revealed that both N-glycosylation sites are used. I-125-mTIMP-1 intraveneously injected into a male Sprague Dawley rat disappeared within 2 min from the circulation. 5 min after injection more than 50% of the I-125-mTIMP-1 were found in the liver and 20% in the kidneys. At later times, trichloroacetic-acid-soluble material accumulated in the intestinal tract.
Stichworte
TISSUE; INHIBITOR OF METALLOPROTEINASE-1; N-GLYCOSYLATION; COLLAGENASE; BACULOVIRUS; METALLOPROTEINASES
Erscheinungsjahr
1995
Zeitschriftentitel
EUROPEAN JOURNAL OF BIOCHEMISTRY
Band
234
Ausgabe
2
Seite(n)
485-491
ISSN
0014-2956
eISSN
1432-1033
Page URI
https://pub.uni-bielefeld.de/record/1629264

Zitieren

KURSCHAT P, GRAEVE L, ERREN A, et al. EXPRESSION OF A BIOLOGICALLY-ACTIVE MURINE TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) IN BACULOVIRUS-INFECTED INSECT CELLS - PURIFICATION AND TISSUE DISTRIBUTION IN THE RAT. EUROPEAN JOURNAL OF BIOCHEMISTRY. 1995;234(2):485-491.
KURSCHAT, P., GRAEVE, L., ERREN, A., GATSIOS, P., ROSEJOHN, S., ROEB, E., Tschesche, H., et al. (1995). EXPRESSION OF A BIOLOGICALLY-ACTIVE MURINE TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) IN BACULOVIRUS-INFECTED INSECT CELLS - PURIFICATION AND TISSUE DISTRIBUTION IN THE RAT. EUROPEAN JOURNAL OF BIOCHEMISTRY, 234(2), 485-491. https://doi.org/10.1111/j.1432-1033.1995.485_b.x
KURSCHAT, P, GRAEVE, L, ERREN, A, GATSIOS, P, ROSEJOHN, S, ROEB, E, Tschesche, Harald, KOJ, A, and HEINRICH, PC. 1995. “EXPRESSION OF A BIOLOGICALLY-ACTIVE MURINE TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) IN BACULOVIRUS-INFECTED INSECT CELLS - PURIFICATION AND TISSUE DISTRIBUTION IN THE RAT”. EUROPEAN JOURNAL OF BIOCHEMISTRY 234 (2): 485-491.
KURSCHAT, P., GRAEVE, L., ERREN, A., GATSIOS, P., ROSEJOHN, S., ROEB, E., Tschesche, H., KOJ, A., and HEINRICH, P. C. (1995). EXPRESSION OF A BIOLOGICALLY-ACTIVE MURINE TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) IN BACULOVIRUS-INFECTED INSECT CELLS - PURIFICATION AND TISSUE DISTRIBUTION IN THE RAT. EUROPEAN JOURNAL OF BIOCHEMISTRY 234, 485-491.
KURSCHAT, P., et al., 1995. EXPRESSION OF A BIOLOGICALLY-ACTIVE MURINE TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) IN BACULOVIRUS-INFECTED INSECT CELLS - PURIFICATION AND TISSUE DISTRIBUTION IN THE RAT. EUROPEAN JOURNAL OF BIOCHEMISTRY, 234(2), p 485-491.
P. KURSCHAT, et al., “EXPRESSION OF A BIOLOGICALLY-ACTIVE MURINE TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) IN BACULOVIRUS-INFECTED INSECT CELLS - PURIFICATION AND TISSUE DISTRIBUTION IN THE RAT”, EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 234, 1995, pp. 485-491.
KURSCHAT, P., GRAEVE, L., ERREN, A., GATSIOS, P., ROSEJOHN, S., ROEB, E., Tschesche, H., KOJ, A., HEINRICH, P.C.: EXPRESSION OF A BIOLOGICALLY-ACTIVE MURINE TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) IN BACULOVIRUS-INFECTED INSECT CELLS - PURIFICATION AND TISSUE DISTRIBUTION IN THE RAT. EUROPEAN JOURNAL OF BIOCHEMISTRY. 234, 485-491 (1995).
KURSCHAT, P, GRAEVE, L, ERREN, A, GATSIOS, P, ROSEJOHN, S, ROEB, E, Tschesche, Harald, KOJ, A, and HEINRICH, PC. “EXPRESSION OF A BIOLOGICALLY-ACTIVE MURINE TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) IN BACULOVIRUS-INFECTED INSECT CELLS - PURIFICATION AND TISSUE DISTRIBUTION IN THE RAT”. EUROPEAN JOURNAL OF BIOCHEMISTRY 234.2 (1995): 485-491.

6 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

PEGylation extends circulation half-life while preserving in vitro and in vivo activity of tissue inhibitor of metalloproteinases-1 (TIMP-1).
Batra J, Robinson J, Mehner C, Hockla A, Miller E, Radisky DC, Radisky ES., PLoS One 7(11), 2012
PMID: 23185522
Brain distribution and elimination of recombinant human TIMP-1 after cerebral ischemia and reperfusion in rats.
Sa Y, Hao J, Samineni D, Clark J, Pyne-Geithman G, Broderick J, Lu A., Neurol Res 33(4), 2011
PMID: 21535944
TIMP-1 inhibits apoptosis in breast carcinoma cells via a pathway involving pertussis toxin-sensitive G protein and c-Src.
Lee SJ, Yoo HJ, Bae YS, Kim HJ, Lee ST., Biochem Biophys Res Commun 312(4), 2003
PMID: 14652000
TIMP-1/MMP-9 imbalance in an EBV-immortalized B lymphocyte cellular model: evidence for TIMP-1 multifunctional properties.
Gaudin P, Trocmé C, Berthier S, Kieffer S, Boutonnat J, Lamy C, Surla A, Garin J, Morel F., Biochim Biophys Acta 1499(1-2), 2000
PMID: 11118636
Oncostatin M differentially regulates tissue inhibitors of metalloproteinases TIMP-1 and TIMP-3 gene expression in human synovial lining cells.
Gatsios P, Haubeck HD, Van de Leur E, Frisch W, Apte SS, Greiling H, Heinrich PC, Graeve L., Eur J Biochem 241(1), 1996
PMID: 8898888

50 References

Daten bereitgestellt von Europe PubMed Central.


AUTHOR UNKNOWN, 0
Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity.
Docherty AJ, Lyons A, Smith BJ, Wright EM, Stephens PE, Harris TJ, Murphy G, Reynolds JJ., Nature 318(6041), 1985
PMID: 3903517
cDNA cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinases.
Boone TC, Johnson MJ, De Clerck YA, Langley KE., Proc. Natl. Acad. Sci. U.S.A. 87(7), 1990
PMID: 2157214
Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues.
Stetler-Stevenson WG, Brown PD, Onisto M, Levy AT, Liotta LA., J. Biol. Chem. 265(23), 1990
PMID: 2380196
The matrix metalloproteinases and their natural inhibitors: prospects for treating degenerative tissue diseases.
Docherty AJ, O'Connell J, Crabbe T, Angal S, Murphy G., Trends Biotechnol. 10(6), 1992
PMID: 1368394
Matrix regulation of cell shape and gene expression.
McDonald JA., Curr. Opin. Cell Biol. 1(5), 1989
PMID: 2697301

Poole, Rheumatology 10(), 1986
Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation.
Liotta LA, Steeg PS, Stetler-Stevenson WG., Cell 64(2), 1991
PMID: 1703045

Bissel, 1992
Role of cytokines and inflammatory mediators in tissue destruction.
Birkedal-Hansen H., J. Periodont. Res. 28(6 Pt 2), 1993
PMID: 8263720
Synthesis of tissue inhibitor of metalloproteinase-1 (TIMP-1) in human hepatoma cells (HepG2). Up-regulation by interleukin-6 and transforming growth factor beta 1.
Kordula T, Guttgemann I, Rose-John S, Roeb E, Osthues A, Tschesche H, Koj A, Heinrich PC, Graeve L., FEBS Lett. 313(2), 1992
PMID: 1330702
Regulation of tissue inhibitor of metalloproteinases-1 gene expression by cytokines and dexamethasone in rat hepatocyte primary cultures.
Roeb E, Graeve L, Hoffmann R, Decker K, Edwards DR, Heinrich PC., Hepatology 18(6), 1993
PMID: 8244270
TIMP-1 protein expression is stimulated by IL-1 beta and IL-6 in primary rat hepatocytes.
Roeb E, Graeve L, Mullberg J, Matern S, Rose-John S., FEBS Lett. 349(1), 1994
PMID: 8045300
Expression and purification of mouse TIMP-1 from E. coli.
Cocuzzi ET, Walther SE, Rajan S, Denhardt DT., FEBS Lett. 307(3), 1992
PMID: 1322839
Synthetic substrates for vertebrate collagenase.
Masui Y, Takemoto T, Sakakibara S, Hori H, Nagai Y., Biochem Med 17(2), 1977
PMID: 193489
The establishment of two cell lines from the insect Spodoptera frugiperda (Lepidoptera; Noctuidae).
Vaughn JL, Goodwin RH, Tompkins GJ, McCawley P., In Vitro 13(4), 1977
PMID: 68913
Baculovirus expression vectors: the requirements for high level expression of proteins, including glycoproteins.
Matsuura Y, Possee RD, Overton HA, Bishop DH., J. Gen. Virol. 68 ( Pt 5)(), 1987
PMID: 3553425
DNA sequencing with chain-terminating inhibitors.
Sanger F, Nicklen S, Coulson AR., Proc. Natl. Acad. Sci. U.S.A. 74(12), 1977
PMID: 271968

Summers, 1987
The recombinant catalytic domain of human neutrophil collagenase lacks type I collagen substrate specificity.
Schnierer S, Kleine T, Gote T, Hillemann A, Knauper V, Tschesche H., Biochem. Biophys. Res. Commun. 191(2), 1993
PMID: 8460992
Deglycosylation of asparagine-linked glycans by peptide:N-glycosidase F.
Tarentino AL, Gomez CM, Plummer TH Jr., Biochemistry 24(17), 1985
PMID: 4063349
Expression of human interferon omega 1 in Sf9 cells. No evidence for complex-type N-linked glycosylation or sialylation.
Voss T, Ergulen E, Ahorn H, Kubelka V, Sugiyama K, Maurer-Fogy I, Glossl J., Eur. J. Biochem. 217(3), 1993
PMID: 8223648
Disulphide bond assignment in human tissue inhibitor of metalloproteinases (TIMP).
Williamson RA, Marston FA, Angal S, Koklitis P, Panico M, Morris HR, Carne AF, Smith BJ, Harris TJ, Freedman RB., Biochem. J. 268(2), 1990
PMID: 2163605
Functional expression and purification of a homomeric human alpha 1 glycine receptor in baculovirus-infected insect cells.
Cascio M, Schoppa NE, Grodzicki RL, Sigworth FJ, Fox RO., J. Biol. Chem. 268(29), 1993
PMID: 8408073
Human serotonin1B receptor expression in Sf9 cells: phosphorylation, palmitoylation, and adenylyl cyclase inhibition.
Ng GY, George SR, Zastawny RL, Caron M, Bouvier M, Dennis M, O'Dowd BF., Biochemistry 32(43), 1993
PMID: 8218242
Expression and secretion of active mouse TIMP-1 using a baculovirus expression vector.
Cocuzzi ET, Walther SE, Denhardt DT., Inflammation 18(1), 1994
PMID: 8206645
Expression and characterization of human tissue inhibitor of metalloproteinases-1 in a baculovirus-insect cell system.
Gomez DE, Lindsay CK, Cottam DW, Nason AM, Thorgeirsson UP., Biochem. Biophys. Res. Commun. 203(1), 1994
PMID: 8074661
Characterization and expression of a murine gene homologous to human EPA/TIMP: a virus-induced gene in the mouse.
Gewert DR, Coulombe B, Castelino M, Skup D, Williams BR., EMBO J. 6(3), 1987
PMID: 3034603
Carbohydrate-specific receptors of the liver.
Ashwell G, Harford J., Annu. Rev. Biochem. 51(), 1982
PMID: 6287920

AUTHOR UNKNOWN, 0
Fate of interleukin-6 in the rat. Involvement of skin in its catabolism.
Castell J, Klapproth J, Gross V, Walter E, Andus T, Snyers L, Content J, Heinrich PC., Eur. J. Biochem. 189(1), 1990
PMID: 2331992
Mannose receptor.
Pontow SE, Kery V, Stahl PD., Int. Rev. Cytol. 137B(), 1992
PMID: 1478821
Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2).
Hayakawa T, Yamashita K, Ohuchi E, Shinagawa A., J. Cell. Sci. 107 ( Pt 9)(), 1994
PMID: 7844157
A matrix metalloproteinase expressed on the surface of invasive tumour cells.
Sato H, Takino T, Okada Y, Cao J, Shinagawa A, Yamamoto E, Seiki M., Nature 370(6484), 1994
PMID: 8015608
Characterization of metalloproteinases and tissue inhibitors of metalloproteinases in human plasma.
Moutsiakis D, Mancuso P, Krutzsch H, Stetler-Stevenson W, Zucker S., Connect. Tissue Res. 28(3), 1992
PMID: 1468208
Serum tissue inhibitor of metalloproteinases in patients with chronic liver disease and with hepatocellular carcinoma.
Murawaki Y, Yamamoto H, Kawasaki H, Shima H., Clin. Chim. Acta 218(1), 1993
PMID: 8299219
Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®
Quellen

PMID: 8536693
PubMed | Europe PMC

Suchen in

Google Scholar