Nuclear and cytoplasmic maturation of mouse oocytes after treatment with synthetic meiosis-activating sterol in vitro
Hegele-Hartung C, Kuhnke J, Lessl M, Grondahl C, Ottesen J, Beier HM, Eisner S, Eichenlaub-Ritter U (1999)
BIOLOGY OF REPRODUCTION 61(5): 1362-1372.
Zeitschriftenaufsatz
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Autor*in
Hegele-Hartung, C;
Kuhnke, J;
Lessl, M;
Grondahl, C;
Ottesen, J;
Beier, HM;
Eisner, S;
Eichenlaub-Ritter, UrsulaUniBi
Abstract / Bemerkung
Synthetically produced meiosis-activating sterol, a sterol originally derived from follicular fluid (FF-MAS), induces meiotic maturation of mouse oocytes in vitro. We therefore compared FF-MAS-induced maturation of naked mouse oocytes arrested in prophase I by either hypoxanthine (Hx) or forskolin (Fo) with spontaneous maturation of naked oocytes. FF-MAS-treated oocytes overcame the meiotic block by Hx or Fo, although germinal vesicle breakdown was delayed by 11 h and 7 h, respectively. We also investigated the influence of FF-MAS on chromosome, microtubule, and ultrastructural dynamics in Hx-cultured oocytes by immunocytochemistry and electron microscopy. Similarly to spontaneously matured oocytes, chromosomes became aligned, a barrel-shaped spindle formed, and overall organelle distribution was normal in FF-MAS-matured oocytes. The number of small cytoplasmic asters was elevated in FF-MAS-treated oocytes. Although the number of cortical granules (CGs) was similar to that in spontaneously matured oocytes, the overall distance between CGs and oolemma was increased in the FF-MAS group. These observations suggest that the initiation of meiotic maturation in FF-MAS-treated oocytes in the presence of high cAMP levels leads to a delayed but otherwise normal nuclear maturation. FF-MAS appears to improve oocyte quality by supporting microtubule assembly and by delaying CG release, which is known to contribute to reduced fertilization.
Erscheinungsjahr
1999
Zeitschriftentitel
BIOLOGY OF REPRODUCTION
Band
61
Ausgabe
5
Seite(n)
1362-1372
ISSN
0006-3363
eISSN
1529-7268
Page URI
https://pub.uni-bielefeld.de/record/1621578
Zitieren
Hegele-Hartung C, Kuhnke J, Lessl M, et al. Nuclear and cytoplasmic maturation of mouse oocytes after treatment with synthetic meiosis-activating sterol in vitro. BIOLOGY OF REPRODUCTION. 1999;61(5):1362-1372.
Hegele-Hartung, C., Kuhnke, J., Lessl, M., Grondahl, C., Ottesen, J., Beier, H. M., Eisner, S., et al. (1999). Nuclear and cytoplasmic maturation of mouse oocytes after treatment with synthetic meiosis-activating sterol in vitro. BIOLOGY OF REPRODUCTION, 61(5), 1362-1372. https://doi.org/10.1095/biolreprod61.5.1362
Hegele-Hartung, C, Kuhnke, J, Lessl, M, Grondahl, C, Ottesen, J, Beier, HM, Eisner, S, and Eichenlaub-Ritter, Ursula. 1999. “Nuclear and cytoplasmic maturation of mouse oocytes after treatment with synthetic meiosis-activating sterol in vitro”. BIOLOGY OF REPRODUCTION 61 (5): 1362-1372.
Hegele-Hartung, C., Kuhnke, J., Lessl, M., Grondahl, C., Ottesen, J., Beier, H. M., Eisner, S., and Eichenlaub-Ritter, U. (1999). Nuclear and cytoplasmic maturation of mouse oocytes after treatment with synthetic meiosis-activating sterol in vitro. BIOLOGY OF REPRODUCTION 61, 1362-1372.
Hegele-Hartung, C., et al., 1999. Nuclear and cytoplasmic maturation of mouse oocytes after treatment with synthetic meiosis-activating sterol in vitro. BIOLOGY OF REPRODUCTION, 61(5), p 1362-1372.
C. Hegele-Hartung, et al., “Nuclear and cytoplasmic maturation of mouse oocytes after treatment with synthetic meiosis-activating sterol in vitro”, BIOLOGY OF REPRODUCTION, vol. 61, 1999, pp. 1362-1372.
Hegele-Hartung, C., Kuhnke, J., Lessl, M., Grondahl, C., Ottesen, J., Beier, H.M., Eisner, S., Eichenlaub-Ritter, U.: Nuclear and cytoplasmic maturation of mouse oocytes after treatment with synthetic meiosis-activating sterol in vitro. BIOLOGY OF REPRODUCTION. 61, 1362-1372 (1999).
Hegele-Hartung, C, Kuhnke, J, Lessl, M, Grondahl, C, Ottesen, J, Beier, HM, Eisner, S, and Eichenlaub-Ritter, Ursula. “Nuclear and cytoplasmic maturation of mouse oocytes after treatment with synthetic meiosis-activating sterol in vitro”. BIOLOGY OF REPRODUCTION 61.5 (1999): 1362-1372.
Daten bereitgestellt von European Bioinformatics Institute (EBI)
35 Zitationen in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
Adenosine Modulates the Oocyte Developmental Competence by Exposing Stages and Synthetic Blocking during In Vitro Maturation.
Cheon YP., Dev Reprod 20(2), 2016
PMID: 27660830
Cheon YP., Dev Reprod 20(2), 2016
PMID: 27660830
Effects of AY9944 A-7 on gonadotropin-induced meiotic resumption of oocytes and development of parthenogenetic embryos in sheep.
Hao R, Zhang C, Lv L, Shi L, Yue W., Theriogenology 83(1), 2015
PMID: 25277529
Hao R, Zhang C, Lv L, Shi L, Yue W., Theriogenology 83(1), 2015
PMID: 25277529
Follicular fluid dehydroepiandrosterone sulfate is a credible marker of oocyte maturity and pregnancy outcome in conventional in vitro fertilization cycles.
Chimote NM, Nath NM, Chimote NN, Chimote BN., J Hum Reprod Sci 8(4), 2015
PMID: 26751787
Chimote NM, Nath NM, Chimote NN, Chimote BN., J Hum Reprod Sci 8(4), 2015
PMID: 26751787
Reduced uterine receptivity for mouse embryos developed from in-vitro matured oocytes.
Lin YH, Tsai CY, Huang LW, Seow KM, Hwang JL, Tzeng CR., J Assist Reprod Genet 31(12), 2014
PMID: 25292155
Lin YH, Tsai CY, Huang LW, Seow KM, Hwang JL, Tzeng CR., J Assist Reprod Genet 31(12), 2014
PMID: 25292155
Folic acid facilitates in vitro maturation of mouse and Xenopus laevis oocytes.
Huang X, Gao S, Xia W, Hou S, Wu K., Br J Nutr 109(8), 2013
PMID: 22932126
Huang X, Gao S, Xia W, Hou S, Wu K., Br J Nutr 109(8), 2013
PMID: 22932126
Gas6 downregulation impaired cytoplasmic maturation and pronuclear formation independent to the MPF activity.
Kim KH, Kim EY, Kim Y, Kim E, Lee HS, Yoon SY, Lee KA., PLoS One 6(8), 2011
PMID: 21850267
Kim KH, Kim EY, Kim Y, Kim E, Lee HS, Yoon SY, Lee KA., PLoS One 6(8), 2011
PMID: 21850267
Effects of lanosterol on in vitro maturation of porcine oocytes.
Marco-Jiménez F, Llobat L, Vicente JS., Anim Reprod Sci 117(3-4), 2010
PMID: 19473792
Marco-Jiménez F, Llobat L, Vicente JS., Anim Reprod Sci 117(3-4), 2010
PMID: 19473792
Reducing CYP51 inhibits follicle-stimulating hormone induced resumption of mouse oocyte meiosis in vitro.
Wang C, Xu B, Zhou B, Zhang C, Yang J, Ouyang H, Ning G, Zhang M, Shen J, Xia G., J Lipid Res 50(11), 2009
PMID: 19433477
Wang C, Xu B, Zhou B, Zhang C, Yang J, Ouyang H, Ning G, Zhang M, Shen J, Xia G., J Lipid Res 50(11), 2009
PMID: 19433477
The signal pathway of gonadotrophins-induced mammalian oocyte meiotic resumption.
Zhang M, Ouyang H, Xia G., Mol Hum Reprod 15(7), 2009
PMID: 19443606
Zhang M, Ouyang H, Xia G., Mol Hum Reprod 15(7), 2009
PMID: 19443606
Involvement of mitogen-activated protein kinase (MAPK) pathway in LH- and meiosis-activating sterol (MAS)-induced maturation in rat and mouse oocytes.
Motola S, Cao X, Popliker M, Tsafriri A., Mol Reprod Dev 75(10), 2008
PMID: 18324668
Motola S, Cao X, Popliker M, Tsafriri A., Mol Reprod Dev 75(10), 2008
PMID: 18324668
Influence of follicular fluid meiosis-activating sterol on aneuploidy rate and precocious chromatid segregation in aged mouse oocytes.
Cukurcam S, Betzendahl I, Michel G, Vogt E, Hegele-Hartung C, Lindenthal B, Eichenlaub-Ritter U., Hum Reprod 22(3), 2007
PMID: 17114196
Cukurcam S, Betzendahl I, Michel G, Vogt E, Hegele-Hartung C, Lindenthal B, Eichenlaub-Ritter U., Hum Reprod 22(3), 2007
PMID: 17114196
Principal findings from a multicenter trial investigating the safety of follicular-fluid meiosis-activating sterol for in vitro maturation of human cumulus-enclosed oocytes.
Smitz J, Picton HM, Platteau P, Rutherford A, Cortvrindt R, Clyde J, Nogueira D, Devroey P, Lyby K, Gröndahl C., Fertil Steril 87(4), 2007
PMID: 17198705
Smitz J, Picton HM, Platteau P, Rutherford A, Cortvrindt R, Clyde J, Nogueira D, Devroey P, Lyby K, Gröndahl C., Fertil Steril 87(4), 2007
PMID: 17198705
Effect of rescuing donated immature human oocytes derived after FSH/hCG stimulation following in vitro culture with or without Follicular Fluid Meiosis Activating Sterol (FF-MAS)--an embryo chromosomal and morphological analysis.
Lundin K, Ziebe S, Bergh C, Loft A, Selleskog U, Nilsson L, Grøndahl C, Joan-Carles Arce for the CEMAS I Study Group., J Assist Reprod Genet 24(2-3), 2007
PMID: 17216347
Lundin K, Ziebe S, Bergh C, Loft A, Selleskog U, Nilsson L, Grøndahl C, Joan-Carles Arce for the CEMAS I Study Group., J Assist Reprod Genet 24(2-3), 2007
PMID: 17216347
Meiosis activating sterol (MAS) regulate FSH-induced meiotic resumption of cumulus cell-enclosed porcine oocytes via PKC pathway.
Jin S, Zhang M, Lei L, Wang C, Fu M, Ning G, Xia G., Mol Cell Endocrinol 249(1-2), 2006
PMID: 16500744
Jin S, Zhang M, Lei L, Wang C, Fu M, Ning G, Xia G., Mol Cell Endocrinol 249(1-2), 2006
PMID: 16500744
Differential response of cumulus cell-enclosed and denuded mouse oocytes in a meiotic induction model system.
Downs SM, Gilles R, Vanderhoef C, Humpherson PG, Leese HJ., Mol Reprod Dev 73(3), 2006
PMID: 16362973
Downs SM, Gilles R, Vanderhoef C, Humpherson PG, Leese HJ., Mol Reprod Dev 73(3), 2006
PMID: 16362973
Follicular sterol composition in gonadotrophin stimulated women with polycystic ovarian syndrome.
Bokal EV, Tacer KF, Vrbnjak M, Leposa S, Virant Klun I, Verdenik I, Rozman D., Mol Cell Endocrinol 249(1-2), 2006
PMID: 16516374
Bokal EV, Tacer KF, Vrbnjak M, Leposa S, Virant Klun I, Verdenik I, Rozman D., Mol Cell Endocrinol 249(1-2), 2006
PMID: 16516374
Lanosterol 14alpha-demethylase expression in the mouse ovary and its participation in cumulus-enclosed oocyte spontaneous meiotic maturation in vitro.
Wang C, Xie H, Song X, Ning G, Yan J, Chen X, Xu B, Ouyang H, Xia G., Theriogenology 66(5), 2006
PMID: 16650467
Wang C, Xie H, Song X, Ning G, Yan J, Chen X, Xu B, Ouyang H, Xia G., Theriogenology 66(5), 2006
PMID: 16650467
Resumption of oocyte meiosis in mammals: on models, meiosis activating sterols, steroids and EGF-like factors.
Tsafriri A, Cao X, Ashkenazi H, Motola S, Popliker M, Pomerantz SH., Mol Cell Endocrinol 234(1-2), 2005
PMID: 15836951
Tsafriri A, Cao X, Ashkenazi H, Motola S, Popliker M, Pomerantz SH., Mol Cell Endocrinol 234(1-2), 2005
PMID: 15836951
Impact of follicular-fluid meiosis-activating sterol in an albumin-based formulation on the incidence of human pre-embryos with chromosome abnormalities.
Loft A, Ziebe S, Erb K, Rasmussen PE, Agerholm I, Hauge B, Bungum M, Bungum L, Grøndahl C, Lyby K., Fertil Steril 84 Suppl 2(), 2005
PMID: 16210020
Loft A, Ziebe S, Erb K, Rasmussen PE, Agerholm I, Hauge B, Bungum M, Bungum L, Grøndahl C, Lyby K., Fertil Steril 84 Suppl 2(), 2005
PMID: 16210020
Stops and starts in mammalian oocytes: recent advances in understanding the regulation of meiotic arrest and oocyte maturation.
Mehlmann LM., Reproduction 130(6), 2005
PMID: 16322539
Mehlmann LM., Reproduction 130(6), 2005
PMID: 16322539
Roles of gonadotropins and meiosis-activating sterols in meiotic resumption of cultured follicle-enclosed mouse oocytes.
Xie H, Xia G, Byskov AG, Andersen CY, Bo S, Tao Y., Mol Cell Endocrinol 218(1-2), 2004
PMID: 15130520
Xie H, Xia G, Byskov AG, Andersen CY, Bo S, Tao Y., Mol Cell Endocrinol 218(1-2), 2004
PMID: 15130520
Meiosis-activating sterol synthesis in rat preovulatory follicle: is it involved in resumption of meiosis?
Cao X, Pomerantz SH, Popliker M, Tsafriri A., Biol Reprod 71(6), 2004
PMID: 15269103
Cao X, Pomerantz SH, Popliker M, Tsafriri A., Biol Reprod 71(6), 2004
PMID: 15269103
Effect of prematuration, meiosis activating sterol and enriched maturation medium on the nuclear maturation and competence to development of calf oocytes.
Donnay I, Faerge I, Grøndahl C, Verhaeghe B, Sayoud H, Ponderato N, Galli C, Lazzari G., Theriogenology 62(6), 2004
PMID: 15289049
Donnay I, Faerge I, Grøndahl C, Verhaeghe B, Sayoud H, Ponderato N, Galli C, Lazzari G., Theriogenology 62(6), 2004
PMID: 15289049
Mouse oocyte meiotic resumption and polar body extrusion in vitro are differentially influenced by FSH, epidermal growth factor and meiosis-activating sterol.
Coticchio G, Rossi G, Borini A, Grøndahl C, Macchiarelli G, Flamigni C, Fleming S, Cecconi S., Hum Reprod 19(12), 2004
PMID: 15347598
Coticchio G, Rossi G, Borini A, Grøndahl C, Macchiarelli G, Flamigni C, Fleming S, Cecconi S., Hum Reprod 19(12), 2004
PMID: 15347598
Physiology of meiosis-activating sterol: endogenous formation and mode of action.
Grøndahl C, Breinholt J, Wahl P, Murray A, Hansen TH, Faerge I, Stidsen CE, Raun K, Hegele-Hartung C., Hum Reprod 18(1), 2003
PMID: 12525452
Grøndahl C, Breinholt J, Wahl P, Murray A, Hansen TH, Faerge I, Stidsen CE, Raun K, Hegele-Hartung C., Hum Reprod 18(1), 2003
PMID: 12525452
Role of meiosis activating sterols, MAS, in induced oocyte maturation.
Byskov AG, Andersen CY, Leonardsen L., Mol Cell Endocrinol 187(1-2), 2002
PMID: 11988327
Byskov AG, Andersen CY, Leonardsen L., Mol Cell Endocrinol 187(1-2), 2002
PMID: 11988327
Is meiosis activating sterol (MAS) an obligatory mediator of meiotic resumption in mammals.
Tsafriri A, Cao X, Vaknin KM, Popliker M., Mol Cell Endocrinol 187(1-2), 2002
PMID: 11988328
Tsafriri A, Cao X, Vaknin KM, Popliker M., Mol Cell Endocrinol 187(1-2), 2002
PMID: 11988328
Meiosis-activating sterol and the maturation of isolated mouse oocytes.
Downs SM, Ruan B, Schroepfer GJ., Biol Reprod 64(1), 2001
PMID: 11133661
Downs SM, Ruan B, Schroepfer GJ., Biol Reprod 64(1), 2001
PMID: 11133661
Role of meiosis-activating sterols in rat oocyte maturation: effects of specific inhibitors and changes in the expression of lanosterol 14alpha-demethylase during the preovulatory period.
Vaknin KM, Lazar S, Popliker M, Tsafriri A., Biol Reprod 64(1), 2001
PMID: 11133687
Vaknin KM, Lazar S, Popliker M, Tsafriri A., Biol Reprod 64(1), 2001
PMID: 11133687
Activation of meiotic maturation in rat oocytes after treatment with follicular fluid meiosis-activating sterol in vitro and ex vivo.
Hegele-Hartung C, Grützner M, Lessl M, Grøndahl C, Ottesen J, Brännström M., Biol Reprod 64(2), 2001
PMID: 11159342
Hegele-Hartung C, Grützner M, Lessl M, Grøndahl C, Ottesen J, Brännström M., Biol Reprod 64(2), 2001
PMID: 11159342
Autoradiographic localization of specific binding of meiosis-activating sterol to cumulus-oocyte complexes from marmoset, cow, and mouse.
Faerge I, Grøndahl C, Ottesen JL, Hyttel P., Biol Reprod 64(2), 2001
PMID: 11159355
Faerge I, Grøndahl C, Ottesen JL, Hyttel P., Biol Reprod 64(2), 2001
PMID: 11159355
The effects of meiosis activating sterol on in-vitro maturation and fertilization of human oocytes from stimulated and unstimulated ovaries.
Cavilla JL, Kennedy CR, Baltsen M, Klentzeris LD, Byskov AG, Hartshorne GM., Hum Reprod 16(3), 2001
PMID: 11228227
Cavilla JL, Kennedy CR, Baltsen M, Klentzeris LD, Byskov AG, Hartshorne GM., Hum Reprod 16(3), 2001
PMID: 11228227
Content of meiosis activating sterols in equine follicular fluids: correlation to follicular size and dominance.
Baltsen M, Bøgh IB, Byskov AG., Theriogenology 56(1), 2001
PMID: 11467509
Baltsen M, Bøgh IB, Byskov AG., Theriogenology 56(1), 2001
PMID: 11467509
Gonadotropin-induced accumulation of 4,4-dimethylsterols in mouse ovaries and its temporal relation to meiosis.
Baltsen M., Biol Reprod 65(6), 2001
PMID: 11717136
Baltsen M., Biol Reprod 65(6), 2001
PMID: 11717136
Resumption of meiosis induced by meiosis-activating sterol has a different signal transduction pathway than spontaneous resumption of meiosis in denuded mouse oocytes cultured in vitro.
Faerge I, Terry B, Kalous J, Wahl P, Lessl M, Ottesen JL, Hyttel P, Grøndahl C., Biol Reprod 65(6), 2001
PMID: 11717137
Faerge I, Terry B, Kalous J, Wahl P, Lessl M, Ottesen JL, Hyttel P, Grøndahl C., Biol Reprod 65(6), 2001
PMID: 11717137
51 References
Daten bereitgestellt von Europe PubMed Central.
Hypoxanthine is the principal inhibitor of murine oocyte maturation in a low molecular weight fraction of porcine follicular fluid.
Downs SM, Coleman DL, Ward-Bailey PF, Eppig JJ., Proc. Natl. Acad. Sci. U.S.A. 82(2), 1985
PMID: 2982158
Downs SM, Coleman DL, Ward-Bailey PF, Eppig JJ., Proc. Natl. Acad. Sci. U.S.A. 82(2), 1985
PMID: 2982158
Hypoxanthine and adenosine in murine ovarian follicular fluid: concentrations and activity in maintaining oocyte meiotic arrest.
Eppig JJ, Ward-Bailey PF, Coleman DL., Biol. Reprod. 33(5), 1985
PMID: 4074802
Eppig JJ, Ward-Bailey PF, Coleman DL., Biol. Reprod. 33(5), 1985
PMID: 4074802
Effect of cyclic AMP on the isolated human oocyte--cumulus complex.
Tornell J, Hillensjo T., Hum. Reprod. 8(5), 1993
PMID: 8391020
Tornell J, Hillensjo T., Hum. Reprod. 8(5), 1993
PMID: 8391020
Gonadotropin-induced resumption of oocyte meiosis and meiosis-activating sterols.
Andersen CY, Baltsen M, Byskov AG., Curr. Top. Dev. Biol. 41(), 1999
PMID: 9784976
Andersen CY, Baltsen M, Byskov AG., Curr. Top. Dev. Biol. 41(), 1999
PMID: 9784976
Regulation of meiotic metaphase by a cytoplasmic maturation-promoting factor during mouse oocyte maturation.
Hashimoto N, Kishimoto T., Dev. Biol. 126(2), 1988
PMID: 3350209
Hashimoto N, Kishimoto T., Dev. Biol. 126(2), 1988
PMID: 3350209
AUTHOR UNKNOWN, 1988
Oocyte control of granulosa cell development: how and why.
AUTHOR UNKNOWN, Hum Reprod 12(Natl Suppl, JBFS 2), 1997
AUTHOR UNKNOWN, Hum Reprod 12(Natl Suppl, JBFS 2), 1997
The influence of glucose, cumulus cells, and metabolic coupling on ATP levels and meiotic control in the isolated mouse oocyte.
Downs SM., Dev. Biol. 167(2), 1995
PMID: 7875374
Downs SM., Dev. Biol. 167(2), 1995
PMID: 7875374
AUTHOR UNKNOWN, 1995
AUTHOR UNKNOWN, 1998
Quantitative studies of changes in cortical granule number and distribution in the mouse oocyte during meiotic maturation.
Ducibella T, Anderson E, Albertini DF, Aalberg J, Rangarajan S., Dev. Biol. 130(1), 1988
PMID: 3141231
Ducibella T, Anderson E, Albertini DF, Aalberg J, Rangarajan S., Dev. Biol. 130(1), 1988
PMID: 3141231
Can developmentally significant spatial patterning of the egg be discounted in mammals?
Gardner RL., Hum. Reprod. Update 2(1), 1996
PMID: 9079400
Gardner RL., Hum. Reprod. Update 2(1), 1996
PMID: 9079400
Polyadenylation and deadenylation of maternal mRNAs during oocyte growth and maturation in the mouse.
Paynton BV, Bachvarova R., Mol. Reprod. Dev. 37(2), 1994
PMID: 7910030
Paynton BV, Bachvarova R., Mol. Reprod. Dev. 37(2), 1994
PMID: 7910030
Specific changes in the pattern of protein synthesis during meiotic maturation of mammalian oocytes in vitro.
Schultz RM, Wassarman PM., Proc. Natl. Acad. Sci. U.S.A. 74(2), 1977
PMID: 191814
Schultz RM, Wassarman PM., Proc. Natl. Acad. Sci. U.S.A. 74(2), 1977
PMID: 191814
Patterns of polypeptide synthesis in mouse oocytes during germinal vesicle breakdown and during maintenance of the germinal vesicle stage by dibutyryl cAMP.
AUTHOR UNKNOWN, Dev Biol 83(), 1983
AUTHOR UNKNOWN, Dev Biol 83(), 1983
Hammond Memorial Lecture. Are follicular maturation and oocyte maturation independent processes?
Thibault C., J. Reprod. Fertil. 51(1), 1977
PMID: 335057
Thibault C., J. Reprod. Fertil. 51(1), 1977
PMID: 335057
Chemical structure of sterols that activate oocyte meiosis.
Byskov AG, Andersen CY, Nordholm L, Thogersen H, Xia G, Wassmann O, Andersen JV, Guddal E, Roed T., Nature 374(6522), 1995
PMID: 7700384
Byskov AG, Andersen CY, Nordholm L, Thogersen H, Xia G, Wassmann O, Andersen JV, Guddal E, Roed T., Nature 374(6522), 1995
PMID: 7700384
Cumulus cells of oocyte-cumulus complexes secrete a meiosis-activating substance when stimulated with FSH.
Byskov AG, Yding Andersen C, Hossaini A, Guoliang X., Mol. Reprod. Dev. 46(3), 1997
PMID: 9041132
Byskov AG, Yding Andersen C, Hossaini A, Guoliang X., Mol. Reprod. Dev. 46(3), 1997
PMID: 9041132
Meiosis-activating sterol promotes resumption of meiosis in mouse oocytes cultured in vitro in contrast to related oxysterols.
Grondahl C, Ottesen JL, Lessl M, Faarup P, Murray A, Gronvald FC, Hegele-Hartung C, Ahnfelt-Ronne I., Biol. Reprod. 58(5), 1998
PMID: 9603267
Grondahl C, Ottesen JL, Lessl M, Faarup P, Murray A, Gronvald FC, Hegele-Hartung C, Ahnfelt-Ronne I., Biol. Reprod. 58(5), 1998
PMID: 9603267
Inhibition of denuded mouse oocyte meiotic maturation by forskolin, an activator of adenylate cyclase.
Urner F, Herrmann WL, Baulieu EE, Schorderet-Slatkine S., Endocrinology 113(3), 1983
PMID: 6191969
Urner F, Herrmann WL, Baulieu EE, Schorderet-Slatkine S., Endocrinology 113(3), 1983
PMID: 6191969
Synthesis of zymosterol, fucosterol, and related biosynthetic sterol intermediates.
AUTHOR UNKNOWN, J Am Chem Soc 111(), 1989
AUTHOR UNKNOWN, J Am Chem Soc 111(), 1989
The CBA mouse as a model for age-related aneuploidy in man: studies of oocyte maturation, spindle formation and chromosome alignment during meiosis.
Eichenlaub-Ritter U, Chandley AC, Gosden RG., Chromosoma 96(3), 1988
PMID: 3359879
Eichenlaub-Ritter U, Chandley AC, Gosden RG., Chromosoma 96(3), 1988
PMID: 3359879
AUTHOR UNKNOWN, 1994
Chloral hydrate induced spindle aberrations, metaphase I arrest and aneuploidy in mouse oocytes.
Eichenlaub-Ritter U, Betzendahl I., Mutagenesis 10(6), 1995
PMID: 8596466
Eichenlaub-Ritter U, Betzendahl I., Mutagenesis 10(6), 1995
PMID: 8596466
Development of preimplantation rabbit embryos after in-vitro culture and embryo transfer: an electron microscopic study.
Hegele-Hartung C, Fischer B, Beier HM., Anat. Rec. 220(1), 1988
PMID: 3348485
Hegele-Hartung C, Fischer B, Beier HM., Anat. Rec. 220(1), 1988
PMID: 3348485
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha.
Janowski BA, Willy PJ, Devi TR, Falck JR, Mangelsdorf DJ., Nature 383(6602), 1996
PMID: 8878485
Janowski BA, Willy PJ, Devi TR, Falck JR, Mangelsdorf DJ., Nature 383(6602), 1996
PMID: 8878485
Protein phosphatases control MAP kinase activation and microtubule organization during rat oocyte maturation.
Zernicka-Goetz M, Verlhac MH, Geraud G, Kubiak JZ., Eur. J. Cell Biol. 72(1), 1997
PMID: 9013723
Zernicka-Goetz M, Verlhac MH, Geraud G, Kubiak JZ., Eur. J. Cell Biol. 72(1), 1997
PMID: 9013723
Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs.
Colledge WH, Carlton MB, Udy GB, Evans MJ., Nature 370(6484), 1994
PMID: 8015609
Colledge WH, Carlton MB, Udy GB, Evans MJ., Nature 370(6484), 1994
PMID: 8015609
Meiotic competence acquisition is associated with the appearance of M-phase characteristics in growing mouse oocytes.
Wickramasinghe D, Ebert KM, Albertini DF., Dev. Biol. 143(1), 1991
PMID: 1985016
Wickramasinghe D, Ebert KM, Albertini DF., Dev. Biol. 143(1), 1991
PMID: 1985016
Immunofluorescent anti-tubulin staining of spindles during meiotic maturation of mouse oocytes in vitro.
Wassarman PM, Fujiwara K., J. Cell. Sci. 29(), 1978
PMID: 75210
Wassarman PM, Fujiwara K., J. Cell. Sci. 29(), 1978
PMID: 75210
Alterations to the microtubular cytoskeleton and increased disorder of chromosome alignment in spontaneously ovulated mouse oocytes aged in vivo: an immunofluorescence study.
Eichenlaub-Ritter U, Chandley AC, Gosden RG., Chromosoma 94(5), 1986
PMID: 3549193
Eichenlaub-Ritter U, Chandley AC, Gosden RG., Chromosoma 94(5), 1986
PMID: 3549193
Non-spindle microtubule organizing centers in metaphase II-arrested mouse oocytes.
Maro B, Howlett SK, Webb M., J. Cell Biol. 101(5 Pt 1), 1985
PMID: 2865266
Maro B, Howlett SK, Webb M., J. Cell Biol. 101(5 Pt 1), 1985
PMID: 2865266
Centrosome and microtubule dynamics during meiotic progression in the mouse oocyte.
AUTHOR UNKNOWN, J Cell Sci 100(), 1991
AUTHOR UNKNOWN, J Cell Sci 100(), 1991
Animal cell cycles and their control.
Norbury C, Nurse P., Annu. Rev. Biochem. 61(), 1992
PMID: 1497317
Norbury C, Nurse P., Annu. Rev. Biochem. 61(), 1992
PMID: 1497317
Mos is required for MAP kinase activation and is involved in microtubule organization during meiotic maturation in the mouse.
Verlhac MH, Kubiak JZ, Weber M, Geraud G, Colledge WH, Evans MJ, Maro B., Development 122(3), 1996
PMID: 8631259
Verlhac MH, Kubiak JZ, Weber M, Geraud G, Colledge WH, Evans MJ, Maro B., Development 122(3), 1996
PMID: 8631259
Oocyte maturation can be induced by a synthetic meiosis activating sterol (MAS) leading to an improvement of IVF rate in mice.
AUTHOR UNKNOWN, Hum Reprod 13(), 1998
AUTHOR UNKNOWN, Hum Reprod 13(), 1998
Chloral hydrate induced spindle aberrations, metaphase I arrest and aneuploidy in mouse oocytes.
Eichenlaub-Ritter U, Betzendahl I., Mutagenesis 10(6), 1995
PMID: 8596466
Eichenlaub-Ritter U, Betzendahl I., Mutagenesis 10(6), 1995
PMID: 8596466
Trichlorfon exposure, spindle aberrations and nondisjunction in mammalian oocytes.
Yin H, Cukurcam S, Betzendahl I, Adler ID, Eichenlaub-Ritter U., Chromosoma 107(6-7), 1998
PMID: 9914385
Yin H, Cukurcam S, Betzendahl I, Adler ID, Eichenlaub-Ritter U., Chromosoma 107(6-7), 1998
PMID: 9914385
AUTHOR UNKNOWN, 1974
Changes in the distribution of mouse oocyte cortical granules and ability to undergo the cortical reaction during gonadotropin-stimulated meiotic maturation and aging in vivo.
Ducibella T, Duffy P, Reindollar R, Su B., Biol. Reprod. 43(5), 1990
PMID: 2291919
Ducibella T, Duffy P, Reindollar R, Su B., Biol. Reprod. 43(5), 1990
PMID: 2291919
AUTHOR UNKNOWN, 1985
Involvement of the cytoskeleton in the movement of cortical granules during oocyte maturation, and cortical granule anchoring in mouse eggs.
AUTHOR UNKNOWN, Dev Biol 200(), 1988
AUTHOR UNKNOWN, Dev Biol 200(), 1988
Spontaneous cortical granule release and alteration of zona pellucida properties during and after meiotic maturation of mouse oocytes.
Okada A, Inomata K, Nagae T., Anat. Rec. 237(4), 1993
PMID: 8311265
Okada A, Inomata K, Nagae T., Anat. Rec. 237(4), 1993
PMID: 8311265
Spontaneous hardening of the zona pellucida of mouse oocytes during in vitro culture.
AUTHOR UNKNOWN, Gamete Res 6(), 1982
AUTHOR UNKNOWN, Gamete Res 6(), 1982
Precocious loss of cortical granules during mouse oocyte meiotic maturation and correlation with an egg-induced modification of the zona pellucida.
Ducibella T, Kurasawa S, Rangarajan S, Kopf GS, Schultz RM., Dev. Biol. 137(1), 1990
PMID: 2104813
Ducibella T, Kurasawa S, Rangarajan S, Kopf GS, Schultz RM., Dev. Biol. 137(1), 1990
PMID: 2104813
Sperm penetration in vitro of mouse oocytes at various times during maturation.
Iwamatsu T, Chang MC., J. Reprod. Fertil. 31(2), 1972
PMID: 4118050
Iwamatsu T, Chang MC., J. Reprod. Fertil. 31(2), 1972
PMID: 4118050
Microtubules and the endoplasmic reticulum are highly interdependent structures.
Terasaki M, Chen LB, Fujiwara K., J. Cell Biol. 103(4), 1986
PMID: 3533956
Terasaki M, Chen LB, Fujiwara K., J. Cell Biol. 103(4), 1986
PMID: 3533956
Microtubule mediation of cytoplasmic and nuclear maturation during the early stages of resumed meiosis in cultured mouse oocytes.
Van Blerkom J., Proc. Natl. Acad. Sci. U.S.A. 88(11), 1991
PMID: 2052585
Van Blerkom J., Proc. Natl. Acad. Sci. U.S.A. 88(11), 1991
PMID: 2052585
Effects of ketoconazole on ovulatory changes in the rat: implications on the role of a meiosis-activating sterol.
Tsafriri A, Popliker M, Nahum R, Beyth Y., Mol. Hum. Reprod. 4(5), 1998
PMID: 9665635
Tsafriri A, Popliker M, Nahum R, Beyth Y., Mol. Hum. Reprod. 4(5), 1998
PMID: 9665635
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