Perspectives for microelectrode arrays for biosensing and membrane electroporation

Neumann E, Tönsing K, Siemens P (2000)
Bioelectrochemistry 51(2): 125-132.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Abstract / Bemerkung
Electrochemical microelectrode devices are among the great challenges for bioelectrochemistry, cell biology and recently also for biomedical research and new clinical electrotherapies. Two representative cases in cell biology and medical research for new trends in the technical devices are selected, heading at new diagnostic and therapeutic clinical applications. One example is from the field of biosensing cholinergic neurotransmitter substances by the nicotinic acetylcholine receptor (AcChoR) in solid-supported lipid bilayer membrane and the other one refers to new developments of electrode systems for the electrochemical delivery of drugs and genes to biological cell aggregates and tissue by the powerful method of membrane electroporation. In both cases addressed to, the new developments include the use of electrical feedback control of electrode arrays for biosensing processes as well as for the extent and duration of tissue electroporation. In line with the impressive advances in medical microsurgery, where increasingly smaller organ targets become accessible, microelectrode systems have become a continuous technical challenge for bioanalytical purposes and, as discussed here in some detail, for the new field of the electroporative delivery of effector substances like drugs and genes, using miniaturized electrochemical electrode arrays. (C)2000 Elsevier Science S.A. All rights reserved.
Stichworte
single current event; acetylcholine receptor; needle electrodes; drug; gene DNA transfer; delivery
Erscheinungsjahr
2000
Zeitschriftentitel
Bioelectrochemistry
Band
51
Ausgabe
2
Seite(n)
125-132
ISSN
1567-5394
Page URI
https://pub.uni-bielefeld.de/record/1617914

Zitieren

Neumann E, Tönsing K, Siemens P. Perspectives for microelectrode arrays for biosensing and membrane electroporation. Bioelectrochemistry. 2000;51(2):125-132.
Neumann, E., Tönsing, K., & Siemens, P. (2000). Perspectives for microelectrode arrays for biosensing and membrane electroporation. Bioelectrochemistry, 51(2), 125-132. doi:10.1016/S0302-4598(99)00084-7
Neumann, E., Tönsing, K., and Siemens, P. (2000). Perspectives for microelectrode arrays for biosensing and membrane electroporation. Bioelectrochemistry 51, 125-132.
Neumann, E., Tönsing, K., & Siemens, P., 2000. Perspectives for microelectrode arrays for biosensing and membrane electroporation. Bioelectrochemistry, 51(2), p 125-132.
E. Neumann, K. Tönsing, and P. Siemens, “Perspectives for microelectrode arrays for biosensing and membrane electroporation”, Bioelectrochemistry, vol. 51, 2000, pp. 125-132.
Neumann, E., Tönsing, K., Siemens, P.: Perspectives for microelectrode arrays for biosensing and membrane electroporation. Bioelectrochemistry. 51, 125-132 (2000).
Neumann, Eberhard, Tönsing, Katja, and Siemens, P. “Perspectives for microelectrode arrays for biosensing and membrane electroporation”. Bioelectrochemistry 51.2 (2000): 125-132.

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 10910160
PubMed | Europe PMC

Suchen in

Google Scholar