Oxal hydroxamic acid derivatives with inhibitory activity against matrix metalloproteinases

Krumme, D; Tschesche, Harald

Oxal hydroxamic acid derivatives with inhibitory activity against matrix metalloproteinases

Krumme D, Tschesche H (2002)
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12(6): 933-936.

Zeitschriftenaufsatz | Veröffentlicht | Englisch

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DOI

https://doi.org/10.1016/S0960-894X(02)00052-5

Autor*in

Krumme, D; Tschesche, Harald^UniBi

Einrichtung

Fakultät für Chemie > Biochemie I

Abstract / Bemerkung

Several amines, amino acid derivatives and low molecular weight peptides containing an amide-bound oxal hydroxamic acid moiety have been synthesized and tested for their inhibitory effects towards native human gelatinase B (MMP-9) and the catalytic domains of the membrane type MT1-MMP (MMP-14) and of neutrophil collagenase (MMP-8). A number of these compounds exhibited considerable inhibitory activity against the tested metalloproteinases. (C) 2002 Elsevier Science Ltd. All rights reserved.

Erscheinungsjahr

2002

Zeitschriftentitel

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Band

Ausgabe

Seite(n)

933-936

ISSN

0960-894X

Page URI

https://pub.uni-bielefeld.de/record/1614644

Zitieren

Krumme D, Tschesche H. Oxal hydroxamic acid derivatives with inhibitory activity against matrix metalloproteinases. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2002;12(6):933-936.

Krumme, D., & Tschesche, H. (2002). Oxal hydroxamic acid derivatives with inhibitory activity against matrix metalloproteinases. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 12(6), 933-936. https://doi.org/10.1016/S0960-894X(02)00052-5

Krumme, D, and Tschesche, Harald. 2002. “Oxal hydroxamic acid derivatives with inhibitory activity against matrix metalloproteinases”. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12 (6): 933-936.

Krumme, D., and Tschesche, H. (2002). Oxal hydroxamic acid derivatives with inhibitory activity against matrix metalloproteinases. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12, 933-936.

Krumme, D., & Tschesche, H., 2002. Oxal hydroxamic acid derivatives with inhibitory activity against matrix metalloproteinases. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 12(6), p 933-936.

D. Krumme and H. Tschesche, “Oxal hydroxamic acid derivatives with inhibitory activity against matrix metalloproteinases”, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 12, 2002, pp. 933-936.

Krumme, D., Tschesche, H.: Oxal hydroxamic acid derivatives with inhibitory activity against matrix metalloproteinases. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 12, 933-936 (2002).

Krumme, D, and Tschesche, Harald. “Oxal hydroxamic acid derivatives with inhibitory activity against matrix metalloproteinases”. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12.6 (2002): 933-936.

Daten bereitgestellt von European Bioinformatics Institute (EBI)

CHEMBL

44 Einträge gefunden, die diesen Artikel zitieren von denen 10 angezeigt werden

N-Hydroxy-N'-{(S)-1-((S)-1-phenyl-ethylcarbamoyl)-2-[4-(3-phenyl-ureido)-phenyl]-ethyl}-oxalamide (CHEMBL: CHEMBL170103)
Type of entity: CHEM

N-Hydroxy-N'-((S)-1-naphthalen-2-yl-ethyl)-oxalamide (CHEMBL: CHEMBL170346)
Type of entity: CHEM

N-Hydroxy-N'-[(S)-1-hydroxycarbamoyl-2-(4-phenoxymethyl-phenyl)-ethyl]-oxalamide (CHEMBL: CHEMBL170625)
Type of entity: CHEM

N-Hydroxy-N'-[(S)-2-naphthalen-1-yl-1-((S)-1-phenyl-ethylcarbamoyl)-ethyl]-oxalamide (CHEMBL: CHEMBL171466)
Type of entity: CHEM

N-Hydroxy-N'-[2-(1H-indol-3-yl)-ethyl]-oxalamide (CHEMBL: CHEMBL171949)
Type of entity: CHEM

N-Hydroxy-N'-[(S)-2-naphthalen-2-yl-1-((S)-1-phenyl-ethylcarbamoyl)-ethyl]-oxalamide (CHEMBL: CHEMBL172180)
Type of entity: CHEM

N-Hydroxy-N'-[(S)-1-(1-naphthalen-1-yl-ethylcarbamoyl)-2-phenyl-ethyl]-oxalamide (CHEMBL: CHEMBL172251)
Type of entity: CHEM

N-[3-(2-Ethyl-hexyloxy)-propyl]-N'-hydroxy-oxalamide (CHEMBL: CHEMBL172874)
Type of entity: CHEM

N-Hydroxy-N'-[(S)-3-methyl-1-((R)-1-phenyl-ethylcarbamoyl)-butyl]-oxalamide (CHEMBL: CHEMBL173284)
Type of entity: CHEM

N-[2-(5-Chloro-1H-indol-3-yl)-ethyl]-N'-hydroxy-oxalamide (CHEMBL: CHEMBL173382)
Type of entity: CHEM

4 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Antiglycation, radical scavenging, and semicarbazide-sensitive amine oxidase inhibitory activities of acetohydroxamic acid in vitro.
Liu YH, Lu YL, Liu DZ, Hou WC., Drug Des Devel Ther 11(), 2017
PMID: 28761331

Antioxidant and nitric oxide production inhibitory activities of galacturonyl hydroxamic acid [Erratum: 2008 Aug. 15, v. 109, issue 4, p. 813-814.]
Liu Yuh-Hwa, Lin Shyr-Yi, Lee Chi-Ching, Hou Wen-Chi., Food Chem 109(1), 2008
PMID: IND44030309

Sweet potato (Ipomoea batatas [L.] Lam 'Tainong 57') storage root mucilage with antioxidant activities in vitro
Huang DJ, Chen HJ, Hou WC, Lin CD, Lin YH., Food Chem 98(4), 2006
PMID: IND43871786

Facile solid-phase synthesis of C-terminal peptide aldehydes and hydroxamates from a common Backbone Amide-Linked (BAL) intermediate.
Gazal S, Masterson LR, Barany G., J Pept Res 66(6), 2005
PMID: 16316448

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