Efficient, racemization-free peptide coupling of N-alkyl amino acids by using amino acid chlorides generated in situ - Total syntheses of the cyclopeptides cyclosporin O and omphalotin A

Sewald N (2002)
Angewandte Chemie International Edition 41(24): 4661-4663.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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DOI
Autor*in
Sewald, NorbertUniBi
Einrichtung
Fakultät für Chemie > Organische Chemie III
Stichworte
coupling reagent; amino acids; bioorganic chemistry; synthesis; triphosgene; total; peptides
Erscheinungsjahr
2002
Zeitschriftentitel
Angewandte Chemie International Edition
Band
41
Ausgabe
24
Seite(n)
4661-4663
ISSN
1433-7851
eISSN
1521-3773
Page URI
https://pub.uni-bielefeld.de/record/1612899

Zitieren

Sewald N. Efficient, racemization-free peptide coupling of N-alkyl amino acids by using amino acid chlorides generated in situ - Total syntheses of the cyclopeptides cyclosporin O and omphalotin A. Angewandte Chemie International Edition. 2002;41(24):4661-4663.
Sewald, N. (2002). Efficient, racemization-free peptide coupling of N-alkyl amino acids by using amino acid chlorides generated in situ - Total syntheses of the cyclopeptides cyclosporin O and omphalotin A. Angewandte Chemie International Edition, 41(24), 4661-4663. https://doi.org/10.1002/anie.200290008
Sewald, Norbert. 2002. “Efficient, racemization-free peptide coupling of N-alkyl amino acids by using amino acid chlorides generated in situ - Total syntheses of the cyclopeptides cyclosporin O and omphalotin A”. Angewandte Chemie International Edition 41 (24): 4661-4663.
Sewald, N. (2002). Efficient, racemization-free peptide coupling of N-alkyl amino acids by using amino acid chlorides generated in situ - Total syntheses of the cyclopeptides cyclosporin O and omphalotin A. Angewandte Chemie International Edition 41, 4661-4663.
Sewald, N., 2002. Efficient, racemization-free peptide coupling of N-alkyl amino acids by using amino acid chlorides generated in situ - Total syntheses of the cyclopeptides cyclosporin O and omphalotin A. Angewandte Chemie International Edition, 41(24), p 4661-4663.
N. Sewald, “Efficient, racemization-free peptide coupling of N-alkyl amino acids by using amino acid chlorides generated in situ - Total syntheses of the cyclopeptides cyclosporin O and omphalotin A”, Angewandte Chemie International Edition, vol. 41, 2002, pp. 4661-4663.
Sewald, N.: Efficient, racemization-free peptide coupling of N-alkyl amino acids by using amino acid chlorides generated in situ - Total syntheses of the cyclopeptides cyclosporin O and omphalotin A. Angewandte Chemie International Edition. 41, 4661-4663 (2002).
Sewald, Norbert. “Efficient, racemization-free peptide coupling of N-alkyl amino acids by using amino acid chlorides generated in situ - Total syntheses of the cyclopeptides cyclosporin O and omphalotin A”. Angewandte Chemie International Edition 41.24 (2002): 4661-4663.

4 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

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Michalak O, Gruza MM, Witkowska A, Bujak I, Cmoch P., Molecules 20(6), 2015
PMID: 26035100
Review backbone N-modified peptides: How to meet the challenge of secondary amine acylation.
Fernández-Llamazares AI, Spengler J, Albericio F., Biopolymers 104(5), 2015
PMID: 26095043
Split-and-pool synthesis and characterization of peptide tertiary amide library.
Gao Y, Kodadek T., J Vis Exp (88), 2014
PMID: 24998250
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Teixidó M, Albericio F, Giralt E., J Pept Res 65(2), 2005
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9 References

Daten bereitgestellt von Europe PubMed Central.


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Thern, Angew. Chem. 114(), 2002
Total synthesis of the nematicidal cyclododecapeptide omphalotin A by using racemization-free triphosgene-mediated couplings in the solid phase.
Thern B, Rudolph J, Jung G., Angew. Chem. Int. Ed. Engl. 41(13), 2002
PMID: 12203574

Sewald, 2002
In situ generation of Fmoc-amino acid chlorides using bis-(trichloromethyl) carbonate and its utilization for difficult couplings in solid-phase peptide synthesis.
Falb E, Yechezkel T, Salitra Y, Gilon C., J. Pept. Res. 53(5), 1999
PMID: 10424345

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Carpino, Tetrahedron 55(), 1999
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