First synthesis of beta(2)-homoamino acid by enantioselective catalysis

Rimkus A, Sewald N (2003)
Organic Letters 5(1): 79-80.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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DOI
Autor*in
Rimkus, A; Sewald, NorbertUniBi
Einrichtung
Fakultät für Chemie > Organische Chemie III
Abstract / Bemerkung
The enantioselective conjugate addition of diethylzinc to the activated nitroolefin methyl 3-nitropropenoate is efficiently catalyzed by copper(I) complexes with BINOL-based enantiopure phosphoramidite ligands. The nitroolefin moiety acts as the predominant Michael acceptor, giving rise to the unambiguous formation of 2-alkyl-3-nitro-propanoates. Moderate to excellent enantioselectivities and high chemical yields are obtained. The product can easily be transformed into a beta(2)-homoamino acid.
Erscheinungsjahr
2003
Zeitschriftentitel
Organic Letters
Band
5
Ausgabe
1
Seite(n)
79-80
ISSN
1523-7060
eISSN
1523-7052
Page URI
https://pub.uni-bielefeld.de/record/1612756

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Rimkus A, Sewald N. First synthesis of beta(2)-homoamino acid by enantioselective catalysis. Organic Letters. 2003;5(1):79-80.
Rimkus, A., & Sewald, N. (2003). First synthesis of beta(2)-homoamino acid by enantioselective catalysis. Organic Letters, 5(1), 79-80. https://doi.org/10.1021/ol027252k
Rimkus, A, and Sewald, Norbert. 2003. “First synthesis of beta(2)-homoamino acid by enantioselective catalysis”. Organic Letters 5 (1): 79-80.
Rimkus, A., and Sewald, N. (2003). First synthesis of beta(2)-homoamino acid by enantioselective catalysis. Organic Letters 5, 79-80.
Rimkus, A., & Sewald, N., 2003. First synthesis of beta(2)-homoamino acid by enantioselective catalysis. Organic Letters, 5(1), p 79-80.
A. Rimkus and N. Sewald, “First synthesis of beta(2)-homoamino acid by enantioselective catalysis”, Organic Letters, vol. 5, 2003, pp. 79-80.
Rimkus, A., Sewald, N.: First synthesis of beta(2)-homoamino acid by enantioselective catalysis. Organic Letters. 5, 79-80 (2003).
Rimkus, A, and Sewald, Norbert. “First synthesis of beta(2)-homoamino acid by enantioselective catalysis”. Organic Letters 5.1 (2003): 79-80.

16 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

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