Regulation of sodium channel activity by capping of actin filaments

Shumilina EV, Negulyaev YA, Morachevskaya EA, Hinssen H, Khaitlina SY (2003)
MOLECULAR BIOLOGY OF THE CELL 14(4): 1709-1716.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Autor*in
Shumilina, EV; Negulyaev, YA; Morachevskaya, EA; Hinssen, HorstUniBi; Khaitlina, SY
Abstract / Bemerkung
Ion transport in various tissues can be regulated by the cortical actin cytoskeleton. Specifically, involvement of actin dynamics in the regulation of nonvoltage-gated sodium channels has been shown. Herein, inside-out patch clamp experiments were performed to study the effect of the heterodimeric actin capping protein CapZ on sodium channel regulation in leukemia K562 cells. The channels were activated by cytochalasin-induced disruption of actin filaments and inactivated by G-actin under ionic conditions promoting rapid actin polymerization. CapZ had no direct effect on channel activity. However, being added together with G-actin, CapZ prevented actin-induced channel inactivation, and this effect occurred at CapZ/actin molar ratios from 1:5 to 1:100. When actin was allowed to polymerize at the plasma membrane to induce partial channel inactivation, subsequent addition of CapZ restored the channel activity. These results can be explained by CapZ-induced inhibition of further assembly of actin filaments at the plasma membrane due to the modification of actin dynamics by CapZ. No effect on the channel activity was observed in response to F-actin, confirming that the mechanism of channel inactivation does not involve interaction of the channel with preformed filaments. Our data show that actin-capping protein can participate in the cytoskeleton-associated regulation of sodium transport in nonexcitable cells.
Erscheinungsjahr
2003
Zeitschriftentitel
MOLECULAR BIOLOGY OF THE CELL
Band
14
Ausgabe
4
Seite(n)
1709-1716
ISSN
1059-1524
Page URI
https://pub.uni-bielefeld.de/record/1612063

Zitieren

Shumilina EV, Negulyaev YA, Morachevskaya EA, Hinssen H, Khaitlina SY. Regulation of sodium channel activity by capping of actin filaments. MOLECULAR BIOLOGY OF THE CELL. 2003;14(4):1709-1716.
Shumilina, E. V., Negulyaev, Y. A., Morachevskaya, E. A., Hinssen, H., & Khaitlina, S. Y. (2003). Regulation of sodium channel activity by capping of actin filaments. MOLECULAR BIOLOGY OF THE CELL, 14(4), 1709-1716. doi:10.1091/mbc.E02-09-0622
Shumilina, E. V., Negulyaev, Y. A., Morachevskaya, E. A., Hinssen, H., and Khaitlina, S. Y. (2003). Regulation of sodium channel activity by capping of actin filaments. MOLECULAR BIOLOGY OF THE CELL 14, 1709-1716.
Shumilina, E.V., et al., 2003. Regulation of sodium channel activity by capping of actin filaments. MOLECULAR BIOLOGY OF THE CELL, 14(4), p 1709-1716.
E.V. Shumilina, et al., “Regulation of sodium channel activity by capping of actin filaments”, MOLECULAR BIOLOGY OF THE CELL, vol. 14, 2003, pp. 1709-1716.
Shumilina, E.V., Negulyaev, Y.A., Morachevskaya, E.A., Hinssen, H., Khaitlina, S.Y.: Regulation of sodium channel activity by capping of actin filaments. MOLECULAR BIOLOGY OF THE CELL. 14, 1709-1716 (2003).
Shumilina, EV, Negulyaev, YA, Morachevskaya, EA, Hinssen, Horst, and Khaitlina, SY. “Regulation of sodium channel activity by capping of actin filaments”. MOLECULAR BIOLOGY OF THE CELL 14.4 (2003): 1709-1716.

14 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Extracellular protease trypsin activates amiloride-insensitive sodium channels in human leukemia cells.
Sudarikova AV, Vasileva VY, Vassilieva IO, Negulyaev YA, Morachevskaya EA, Chubinskiy-Nadezhdin VI., J Cell Biochem 120(1), 2019
PMID: 30203535
Noonan Syndrome-Associated SHP2 Dephosphorylates GluN2B to Regulate NMDA Receptor Function.
Levy AD, Xiao X, Shaw JE, Sudarsana Devi SP, Katrancha SM, Bennett AM, Greer CA, Howe JR, Machida K, Koleske AJ., Cell Rep 24(6), 2018
PMID: 30089263
Serum- and glucocorticoid-inducible kinase SGK1 regulates reorganization of actin cytoskeleton in mast cells upon degranulation.
Schmid E, Gu S, Yang W, Münzer P, Schaller M, Lang F, Stournaras C, Shumilina E., Am J Physiol Cell Physiol 304(1), 2013
PMID: 23015548
Role of submembranous actin cytoskeleton in regulation of non-voltage-gated sodium channels.
Chubinskiy-Nadezhdin VI, Sudarikova AV, Nikolsky NN, Morachevskaya EA., Dokl Biochem Biophys 450(), 2013
PMID: 23824452
Common mechanisms regulating cell cortex properties during cell division and cell migration.
Roubinet C, Tran PT, Piel M., Cytoskeleton (Hoboken) 69(11), 2012
PMID: 23125194
Cell mechanics: integrating cell responses to mechanical stimuli.
Janmey PA, McCulloch CA., Annu Rev Biomed Eng 9(), 2007
PMID: 17461730
Magnesium permeation through mechanosensitive channels: single-current measurements.
Staruschenko AV, Sudarikova AV, Negulyaev YA, Morachevskaya EA., Cell Res 16(8), 2006
PMID: 16871269
Gelsolin mediates collagen phagocytosis through a rac-dependent step.
Arora PD, Glogauer M, Kapus A, Kwiatkowski DJ, McCulloch CA., Mol Biol Cell 15(2), 2004
PMID: 14617805
Filamentous-actins in human hepatocarcinoma cells with CLSM.
Huo X, Xu XJ, Chen YW, Yang HW, Piao ZX., World J Gastroenterol 10(11), 2004
PMID: 15162547
Developmental evolution of the delayed rectifier current IKs in canine heart appears dependent on the beta subunit minK.
Krishnamurthy G, Patberg KW, Obreztchikova MN, Rybin AV, Rosen MR., Heart Rhythm 1(6), 2004
PMID: 15851242
Non-hydrolyzable analog of GTP induces activity of Na+ channels via disassembly of cortical actin cytoskeleton.
Shumilina EV, Khaitlina SY, Morachevskaya EA, Negulyaev YA., FEBS Lett 547(1-3), 2003
PMID: 12860381

45 References

Daten bereitgestellt von Europe PubMed Central.

Effects of CapZ, an actin capping protein of muscle, on the polymerization of actin.
Caldwell JE, Heiss SG, Mermall V, Cooper JA., Biochemistry 28(21), 1989
PMID: 2557904
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.
Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ., Pflugers Arch. 391(2), 1981
PMID: 6270629
Amiloride-sensitive sodium channel is linked to the cytoskeleton in renal epithelial cells.
Smith PR, Saccomani G, Joe EH, Angelides KJ, Benos DJ., Proc. Natl. Acad. Sci. U.S.A. 88(16), 1991
PMID: 1651488
Actin filaments regulate epithelial Na+ channel activity.
Cantiello HF, Stow JL, Prat AG, Ausiello DA., Am. J. Physiol. 261(5 Pt 1), 1991
PMID: 1659214
Calcium-induced actin depolymerization reduces NMDA channel activity.
Rosenmund C, Westbrook GL., Neuron 10(5), 1993
PMID: 7684233
Cytoskeletal regulation of ion channel distribution in the tip-growing organism Saprolegnia ferax.
Levina NN, Lew RR, Heath IB., J. Cell. Sci. 107 ( Pt 1)(), 1994
PMID: 7513711
Ankyrin and spectrin associate with voltage-dependent sodium channels in brain.
Srinivasan Y, Elmer L, Davis J, Bennett V, Angelides K., Nature 333(6169), 1988
PMID: 2452986
Control of actin assembly at filament ends.
Schafer DA, Cooper JA., Annu. Rev. Cell Dev. Biol. 11(), 1995
PMID: 8689567
Regulation of epithelial sodium channels by short actin filaments.
Berdiev BK, Prat AG, Cantiello HF, Ausiello DA, Fuller CM, Jovov B, Benos DJ, Ismailov II., J. Biol. Chem. 271(30), 1996
PMID: 8663510
Coordinated regulation of platelet actin filament barbed ends by gelsolin and capping protein.
Barkalow K, Witke W, Kwiatkowski DJ, Hartwig JH., J. Cell Biol. 134(2), 1996
PMID: 8707824
[Aldosterone increases the activity level of Na+-conducting channels in chronic myeloid leukemia K562 cells].
Neguliaev IuA, Vedernikova EA, Maksimov AV., Dokl. Akad. Nauk. 349(5), 1996
PMID: 8963242
Ca-dependent regulation of Na+-selective channels via actin cytoskeleton modification in leukemia cells.
Maximov AV, Vedernikova EA, Hinssen H, Khaitlina SY, Negulyaev YA., FEBS Lett. 412(1), 1997
PMID: 9257697
Characterization of a sodium-response transcriptional mechanism.
Ruiz-Opazo N, Cloix JF, Melis MG, Xiang XH, Herrera VL., Hypertension 30(2 Pt 1), 1997
PMID: 9260979
Functional significance of cell volume regulatory mechanisms.
Lang F, Busch GL, Ritter M, Volkl H, Waldegger S, Gulbins E, Haussinger D., Physiol. Rev. 78(1), 1998
PMID: 9457175
Visualization and molecular analysis of actin assembly in living cells.
Schafer DA, Welch MD, Machesky LM, Bridgman PC, Meyer SM, Cooper JA., J. Cell Biol. 143(7), 1998
PMID: 9864364
Cdc42-induced actin filaments are protected from capping protein.
Huang M, Yang C, Schafer DA, Cooper JA, Higgs HN, Zigmond SH., Curr. Biol. 9(17), 1999
PMID: 10508585
Na+-dependent release of intracellular Ca2+ induced by purinoceptors in parotid acinar cells of the rat.
Fukushi Y, Ozawa T, Kanno T, Wakui M., Eur. J. Pharmacol. 336(1), 1997
PMID: 9384258
Sodium current-induced calcium signals in isolated guinea-pig ventricular myocytes.
Lipp P, Niggli E., J. Physiol. (Lond.) 474(3), 1994
PMID: 8014905
Involvement of actin cytoskeleton in modulation of apical K channel activity in rat collecting duct.
Wang WH, Cassola A, Giebisch G., Am. J. Physiol. 267(4 Pt 2), 1994
PMID: 7943357
Effects of sodium on PKC translocation; relationship to neurotransmitter release.
Basudev H, Romano-Silva MA, Brammer MJ, Campbell IC., Neuroreport 6(5), 1995
PMID: 7541658
Effects of vasopressin and aldosterone on the lateral mobility of epithelial Na+ channels in A6 renal epithelial cells.
Smith PR, Stoner LC, Viggiano SC, Angelides KJ, Benos DJ., J. Membr. Biol. 147(2), 1995
PMID: 8568855
Modulation of a volume-regulated chloride current by F-actin.
Levitan I, Almonte C, Mollard P, Garber SS., J. Membr. Biol. 147(3), 1995
PMID: 8558594
Biochemical characterization of ezrin-actin interaction.
Yao X, Cheng L, Forte JG., J. Biol. Chem. 271(12), 1996
PMID: 8636161
Role of gelsolin in the actin filament regulation of cardiac L-type calcium channels.
Lader AS, Kwiatkowski DJ, Cantiello HF., Am. J. Physiol. 277(6), 1999
PMID: 10600780
In vitro refolding of heterodimeric CapZ expressed in E. coli as inclusion body protein.
Remmert K, Vullhorst D, Hinssen H., Protein Expr. Purif. 18(1), 2000
PMID: 10648164
Control of actin assembly and disassembly at filament ends.
Cooper JA, Schafer DA., Curr. Opin. Cell Biol. 12(1), 2000
PMID: 10679358
Actin machinery: pushing the envelope.
Borisy GG, Svitkina TM., Curr. Opin. Cell Biol. 12(1), 2000
PMID: 10679366
Molecular mechanisms controlling actin filament dynamics in nonmuscle cells.
Pollard TD, Blanchoin L, Mullins RD., Annu Rev Biophys Biomol Struct 29(), 2000
PMID: 10940259
Sodium channel activity in leukemia cells is directly controlled by actin polymerization.
Negulyaev YA, Khaitlina SY, Hinssen H, Shumilina EV, Vedernikova EA., J. Biol. Chem. 275(52), 2000
PMID: 11016945
Cell volume-sensitive sodium channels upregulated by glucocorticoids in U937 macrophages.
Gamper N, Huber SM, Badawi K, Lang F., Pflugers Arch. 441(2-3), 2000
PMID: 11211114
P-glycoprotein-actin association through ERM family proteins: a role in P-glycoprotein function in human cells of lymphoid origin.
Luciani F, Molinari A, Lozupone F, Calcabrini A, Lugini L, Stringaro A, Puddu P, Arancia G, Cianfriglia M, Fais S., Blood 99(2), 2002
PMID: 11781249
Ion transport proteins anchor and regulate the cytoskeleton.
Denker SP, Barber DL., Curr. Opin. Cell Biol. 14(2), 2002
PMID: 11891121

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 12686620
PubMed | Europe PMC

Suchen in

Google Scholar