Solid phase synthesis of an amphiphilic peptide modified for immobilisation at the C-terminus

Wilking SD, Sewald N (2004)
JOURNAL OF BIOTECHNOLOGY 112(1-2): 109-114.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Abstract / Bemerkung
The solid phase peptide synthesis (SPPS) of the amphiphilic peptide Ac-(Leu-Ala-Arg-Leu)(3)-linker, which is modified at the C-terminus with 1,8-diamino-3,6-dioxaoctane as linker moiety, has been investigated. Two different approaches that allow for the synthesis of C-terminally modified, side-chain protected peptides were examined. The solid phase peptide synthesis using aliphatic safety-catch resin followed by activation and aminolysis with the mono-Boc protected linker was compared with the synthesis on 1,8-diamino-3,6-dioxaoctane loaded 2-chlorotrityl resin. (C) 2004 Elsevier B.V. All rights reserved.
Stichworte
amphiphilic peptides; safety-catch resin; phase peptide synthesis; solid; 2-chlorotrityl resin
Erscheinungsjahr
2004
Zeitschriftentitel
JOURNAL OF BIOTECHNOLOGY
Band
112
Ausgabe
1-2
Seite(n)
109-114
ISSN
0168-1656
Page URI
https://pub.uni-bielefeld.de/record/1606707

Zitieren

Wilking SD, Sewald N. Solid phase synthesis of an amphiphilic peptide modified for immobilisation at the C-terminus. JOURNAL OF BIOTECHNOLOGY. 2004;112(1-2):109-114.
Wilking, S. D., & Sewald, N. (2004). Solid phase synthesis of an amphiphilic peptide modified for immobilisation at the C-terminus. JOURNAL OF BIOTECHNOLOGY, 112(1-2), 109-114. doi:10.1016/j.jbiotec.2004.03.016
Wilking, S. D., and Sewald, N. (2004). Solid phase synthesis of an amphiphilic peptide modified for immobilisation at the C-terminus. JOURNAL OF BIOTECHNOLOGY 112, 109-114.
Wilking, S.D., & Sewald, N., 2004. Solid phase synthesis of an amphiphilic peptide modified for immobilisation at the C-terminus. JOURNAL OF BIOTECHNOLOGY, 112(1-2), p 109-114.
S.D. Wilking and N. Sewald, “Solid phase synthesis of an amphiphilic peptide modified for immobilisation at the C-terminus”, JOURNAL OF BIOTECHNOLOGY, vol. 112, 2004, pp. 109-114.
Wilking, S.D., Sewald, N.: Solid phase synthesis of an amphiphilic peptide modified for immobilisation at the C-terminus. JOURNAL OF BIOTECHNOLOGY. 112, 109-114 (2004).
Wilking, SD, and Sewald, Norbert. “Solid phase synthesis of an amphiphilic peptide modified for immobilisation at the C-terminus”. JOURNAL OF BIOTECHNOLOGY 112.1-2 (2004): 109-114.

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