The cost of a specific immune response in young guinea pigs
Pilorz V, Jackel M, Knudsen K, Trillmich F (2005)
PHYSIOLOGY & BEHAVIOR 85(2): 205-211.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Pilorz, V;
Jackel, M;
Knudsen, K;
Trillmich, FritzUniBi ![](https://pub.uni-bielefeld.de/images/icon_orcid.png)
![](https://pub.uni-bielefeld.de/images/icon_orcid.png)
Einrichtung
Abstract / Bemerkung
The specific immune system is a protective mechanism that detects infection and fights it by production of antibodies. Newborns are especially susceptible to infections because their immune system is not yet as fully developed as that of adults. This has been well established in altricial mammals. Fighting infection is associated with costs (metabolic rate, protein synthesis) potentially affecting other developmental processes. We investigated the specific immune response in a precocial mammal, by testing the response of 3 and 7 day old young guinea pigs (Cavia aperea f. porcellus) against a non-pathogenic antigen (KLH) and determined the effect of the immune response on growth and metabolic rate. Challenged young produced a substantial specific immune response (IgG). The efficiency of the immune response was almost identical in 3 and 7 day old young, but lower than in adult females. Antibody titres achieved by actively immunised young pups were as high as titres transferred transplacentally by mothers immunised on day 40 and 47 of pregnancy. In comparison to a control group, the immune response did not influence growth and metabolic rate measured on day 4 after each immune challenge and was not reflected by changes in hematocrit value. We discuss whether the weaker immune response of pups is caused by reduced allocation of limited resources in growing young or by the immature immune system of young animals. (c) 2005 Elsevier Inc. All rights reserved.
Stichworte
precociality;
IgG;
newborn;
pups;
porcellus;
metabolic rate;
Cavia aperea f.
Erscheinungsjahr
2005
Zeitschriftentitel
PHYSIOLOGY & BEHAVIOR
Band
85
Ausgabe
2
Seite(n)
205-211
ISSN
0031-9384
Page URI
https://pub.uni-bielefeld.de/record/1603409
Zitieren
Pilorz V, Jackel M, Knudsen K, Trillmich F. The cost of a specific immune response in young guinea pigs. PHYSIOLOGY & BEHAVIOR. 2005;85(2):205-211.
Pilorz, V., Jackel, M., Knudsen, K., & Trillmich, F. (2005). The cost of a specific immune response in young guinea pigs. PHYSIOLOGY & BEHAVIOR, 85(2), 205-211. https://doi.org/10.1016/j.physbeh.2005.04.008
Pilorz, V, Jackel, M, Knudsen, K, and Trillmich, Fritz. 2005. “The cost of a specific immune response in young guinea pigs”. PHYSIOLOGY & BEHAVIOR 85 (2): 205-211.
Pilorz, V., Jackel, M., Knudsen, K., and Trillmich, F. (2005). The cost of a specific immune response in young guinea pigs. PHYSIOLOGY & BEHAVIOR 85, 205-211.
Pilorz, V., et al., 2005. The cost of a specific immune response in young guinea pigs. PHYSIOLOGY & BEHAVIOR, 85(2), p 205-211.
V. Pilorz, et al., “The cost of a specific immune response in young guinea pigs”, PHYSIOLOGY & BEHAVIOR, vol. 85, 2005, pp. 205-211.
Pilorz, V., Jackel, M., Knudsen, K., Trillmich, F.: The cost of a specific immune response in young guinea pigs. PHYSIOLOGY & BEHAVIOR. 85, 205-211 (2005).
Pilorz, V, Jackel, M, Knudsen, K, and Trillmich, Fritz. “The cost of a specific immune response in young guinea pigs”. PHYSIOLOGY & BEHAVIOR 85.2 (2005): 205-211.
7 Zitationen in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
Correlated response in body condition and energy mobilisation in rabbits selected for litter size variability.
García ML, Blasco A, García ME, Argente MJ., Animal 13(4), 2019
PMID: 30152305
García ML, Blasco A, García ME, Argente MJ., Animal 13(4), 2019
PMID: 30152305
Locally elevated cortisol in lymphoid organs of the developing zebra finch but not Japanese quail or chicken.
Taves MD, Losie JA, Rahim T, Schmidt KL, Sandkam BA, Ma C, Silversides FG, Soma KK., Dev Comp Immunol 54(1), 2016
PMID: 26366679
Taves MD, Losie JA, Rahim T, Schmidt KL, Sandkam BA, Ma C, Silversides FG, Soma KK., Dev Comp Immunol 54(1), 2016
PMID: 26366679
Immunocompetence of breeding females is sensitive to cortisol levels but not to communal rearing in the degu (Octodon degus).
Ebensperger LA, León C, Ramírez-Estrada J, Abades S, Hayes LD, Nova E, Salazar F, Bhattacharjee J, Becker MI., Physiol Behav 140(), 2015
PMID: 25497887
Ebensperger LA, León C, Ramírez-Estrada J, Abades S, Hayes LD, Nova E, Salazar F, Bhattacharjee J, Becker MI., Physiol Behav 140(), 2015
PMID: 25497887
Assessing the energetic costs and trade-offs of a PHA-induced inflammation in the subterranean rodent Ctenomys talarum: immune response in growing tuco-tucos.
Cutrera AP, Luna F, Merlo JL, Baldo MB, Zenuto RR., Comp Biochem Physiol A Mol Integr Physiol 174(), 2014
PMID: 24726606
Cutrera AP, Luna F, Merlo JL, Baldo MB, Zenuto RR., Comp Biochem Physiol A Mol Integr Physiol 174(), 2014
PMID: 24726606
Effect of dietary restriction on immune response of laboratory mice divergently selected for basal metabolic rate.
Książek A, Konarzewski M., Physiol Biochem Zool 85(1), 2012
PMID: 22237289
Książek A, Konarzewski M., Physiol Biochem Zool 85(1), 2012
PMID: 22237289
Immuno-modulation and anti-inflammatory benefits of antibiotics: the example of tilmicosin.
Buret AG., Can J Vet Res 74(1), 2010
PMID: 20357951
Buret AG., Can J Vet Res 74(1), 2010
PMID: 20357951
Seasonal changes in vertebrate immune activity: mediation by physiological trade-offs.
Martin LB, Weil ZM, Nelson RJ., Philos Trans R Soc Lond B Biol Sci 363(1490), 2008
PMID: 17638690
Martin LB, Weil ZM, Nelson RJ., Philos Trans R Soc Lond B Biol Sci 363(1490), 2008
PMID: 17638690
Export
Markieren/ Markierung löschen
Markierte Publikationen
Web of Science
Dieser Datensatz im Web of Science®Quellen
PMID: 15885720
PubMed | Europe PMC
Suchen in